Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionmetalloendopeptidase activity

MMP25 PAPPA2 MBTPS1 MMP17

6.30e-05120364GO:0004222
GeneOntologyMolecularFunctionmetallopeptidase activity

MMP25 PAPPA2 MBTPS1 MMP17

4.48e-04200364GO:0008237
DomainDS_RBD

DICER1 SON STAU1

7.83e-0621353PS50137
Domain-

DICER1 SON STAU1

1.71e-05273533.30.160.20
DomaindsRBD_dom

DICER1 SON STAU1

1.91e-0528353IPR014720
DomainMetalloPept_cat_dom

MMP25 PAPPA2 MMP17

4.65e-0481353IPR024079
Domain-

MMP25 PAPPA2 MMP17

4.65e-04813533.40.390.10
DomainPept_M10A_stromelysin-type

MMP25 MMP17

5.12e-0418352IPR016293
DomainDSRM

DICER1 STAU1

5.72e-0419352SM00358
Domaindsrm

DICER1 STAU1

6.35e-0420352PF00035
DomainPG_binding_1

MMP25 MMP17

6.35e-0420352PF01471
DomainPeptidoglycan-bd-like

MMP25 MMP17

6.35e-0420352IPR002477
DomainZINC_PROTEASE

MMP25 PAPPA2 MMP17

8.12e-0498353PS00142
DomainHemopexin-like_dom

MMP25 MMP17

8.42e-0423352IPR000585
DomainHemopexin

MMP25 MMP17

8.42e-0423352PF00045
DomainHEMOPEXIN

MMP25 MMP17

8.42e-0423352PS00024
Domain-

MMP25 MMP17

8.42e-04233522.110.10.10
DomainHEMOPEXIN_2

MMP25 MMP17

8.42e-0423352PS51642
DomainHemopexin-like_repeat

MMP25 MMP17

8.42e-0423352IPR018487
DomainHX

MMP25 MMP17

8.42e-0423352SM00120
Domainzf-CCHC

ZCCHC2 RBBP6

8.42e-0423352PF00098
DomainPept_M10A

MMP25 MMP17

8.42e-0423352IPR021190
DomainM10A_MMP

MMP25 MMP17

8.42e-0423352IPR033739
DomainPeptidase_M10

MMP25 MMP17

9.18e-0424352PF00413
Domain-

ZCCHC2 RBBP6

1.08e-03263524.10.60.10
DomainZnMc

MMP25 MMP17

1.34e-0329352SM00235
DomainPeptidase_Metallo

MMP25 MMP17

1.34e-0329352IPR006026
DomainZF_CCHC

ZCCHC2 RBBP6

1.95e-0335352PS50158
DomainCYSTEINE_SWITCH

MMP25 MMP17

2.67e-0341352PS00546
DomainPept_M10_metallopeptidase

MMP25 MMP17

2.94e-0343352IPR001818
DomainZnF_C2HC

ZCCHC2 RBBP6

4.76e-0355352SM00343
DomainZnf_CCHC

ZCCHC2 RBBP6

4.76e-0355352IPR001878
Pubmed

Activation of the Hippo pathway by CTLA-4 regulates the expression of Blimp-1 in the CD8+ T cell.

CTLA4 PRDM1

1.04e-06236222745171
Pubmed

Elevated Plasma Levels of MT4-MMP and MT6-MMP; A New Observation in Patients with Thyroid Nodules.

MMP25 MMP17

1.04e-06236238310435
Pubmed

The HOX complex neighbored by the EVX gene, as well as two other homeobox-containing genes, the GBX-class and the EN-class, are located on the same chromosomes 2 and 7 in humans.

GBX1 GBX2

3.12e-0633627903253
Pubmed

The role of Dicer protein partners in the processing of microRNA precursors.

RBBP6 DICER1

6.24e-06436222163034
Pubmed

Reduced transcript expression of genes affected by inherited and de novo CNVs in autism.

ARID1B PRODH

6.24e-06436221448237
Pubmed

High resolution mapping of chromosomal regions controlling resistance to gastrointestinal nematode infections in an advanced intercross line of mice.

PARD3B CTLA4

1.04e-05536216783640
Pubmed

Spatially restricted expression of Dlx-1, Dlx-2 (Tes-1), Gbx-2, and Wnt-3 in the embryonic day 12.5 mouse forebrain defines potential transverse and longitudinal segmental boundaries.

GBX1 GBX2

1.04e-0553627687285
Pubmed

Cloning and embryonic expression analysis of the mouse Gbx1 gene.

GBX1 GBX2

1.04e-05536212799077
Pubmed

Isolation and expression of the homeobox gene Gbx1 during mouse development.

GBX1 GBX2

1.04e-05536214745958
Pubmed

Fine mapping, gene content, comparative sequencing, and expression analyses support Ctla4 and Nramp1 as candidates for Idd5.1 and Idd5.2 in the nonobese diabetic mouse.

PARD3B CTLA4

1.04e-05536215210771
Pubmed

Comprehensive comparative homeobox gene annotation in human and mouse.

GBX1 GBX2

1.04e-05536226412852
Pubmed

Gbx1 and Gbx2 Are Essential for Normal Patterning and Development of Interneurons and Motor Neurons in the Embryonic Spinal Cord.

GBX1 GBX2

1.04e-05536232244588
Pubmed

Developmental specification of forebrain cholinergic neurons.

GBX1 GBX2

1.56e-05636227847324
Pubmed

Membrane-type matrix metalloproteinases: Their functions and regulations.

MMP25 MMP17

2.18e-05736225794647
Pubmed

Elongation factor 1 alpha1 and genes associated with Usher syndromes are downstream targets of GBX2.

GBX1 GBX2

3.73e-05936223144817
Pubmed

Detection of homeobox genes in development and evolution.

GBX1 GBX2

3.73e-0593621720547
Pubmed

The LIM-homeobox gene Lhx8 is required for the development of many cholinergic neurons in the mouse forebrain.

GBX1 GBX2

4.66e-051036212855770
Pubmed

Maf family transcription factors are required for nutrient uptake in the mouse neonatal gut.

TREH PRDM1

8.07e-051336236504079
Pubmed

Blimp1 regulates the transition of neonatal to adult intestinal epithelium.

TREH PRDM1

8.07e-051336221878906
Pubmed

The mouse homeobox gene Gbx2 is required for the development of cholinergic interneurons in the striatum.

GBX1 GBX2

9.41e-051436221048141
Pubmed

Expression of the Ladybird-like homeobox 2 transcription factor in the developing mouse testis and epididymis.

GBX1 GBX2

1.08e-041536218304314
Pubmed

Tooth morphogenesis and ameloblast differentiation are regulated by micro-RNAs.

DICER1 STAU1

1.24e-041636220102707
Pubmed

The transcriptional repressor Blimp1/Prdm1 regulates postnatal reprogramming of intestinal enterocytes.

TREH PRDM1

2.16e-042136221670299
Pubmed

Ldb1 is essential for development of Nkx2.1 lineage derived GABAergic and cholinergic neurons in the telencephalon.

GBX1 GBX2

2.16e-042136224157949
Pubmed

Matrix metalloproteinases.

MMP25 MMP17

2.38e-042236210419448
Pubmed

Functional interactions between matrix metalloproteinases and glycosaminoglycans.

MMP25 MMP17

2.38e-042236223421805
Pubmed

Transcription Factor VAX1 Regulates the Regional Specification of the Subpallium Through Repressing Gsx2.

GBX1 GBX2

2.38e-042236233821423
Pubmed

Functional proteomics mapping of a human signaling pathway.

PAPPA2 ARID1B RBBP6 SON STAU1

3.40e-0459136515231748
Pubmed

A unilateral negative feedback loop between miR-200 microRNAs and Sox2/E2F3 controls neural progenitor cell-cycle exit and differentiation.

GBX2 DICER1

3.60e-042736222993445
Pubmed

Wnt1-cre-mediated conditional loss of Dicer results in malformation of the midbrain and cerebellum and failure of neural crest and dopaminergic differentiation in mice.

GBX2 DICER1

4.75e-043136220457670
Pubmed

MEGF10 and MEGF11 mediate homotypic interactions required for mosaic spacing of retinal neurons.

PAPPA2 MMP17

6.07e-043536222407321
Pubmed

Interferon gamma receptor 2 gene variants are associated with liver fibrosis in patients with chronic hepatitis C infection.

MMP25 MMP17

6.42e-043636220587546
Pubmed

Transcriptional Networks Controlled by NKX2-1 in the Development of Forebrain GABAergic Neurons.

GBX1 GBX2

7.93e-044036227657450
Pubmed

Proteome analysis of the HIV-1 Gag interactome.

DICER1 STAU1

9.59e-044436225010285
GeneFamilyEndogenous ligands|Matrix metallopeptidases

MMP25 MMP17

4.97e-0424252891
GeneFamilyHOXL subclass homeoboxes

GBX1 GBX2

2.33e-0352252518
CoexpressionAtlasdev gonad_e11.5_F_PrimGermCell_Oct_k-means-cluster#1_top-relative-expression-ranked_100

ENPP3 PRDM1

2.49e-062342gudmap_dev gonad_e11.5_F_PrimGermCell_Oct_k1_100
CoexpressionAtlasdev gonad_e12.5_M_GermCellTestis_Oct_k-means-cluster#1_top-relative-expression-ranked_100

ENPP3 PRDM1

2.49e-062342gudmap_dev gonad_e12.5_M_GermCellTestis_Oct_k1_100
CoexpressionAtlasdev gonad_e12.5_F_GermCellOvary_Oct_k-means-cluster#3_top-relative-expression-ranked_100

ENPP3 PRDM1

7.46e-063342gudmap_dev gonad_e12.5_F_GermCellOvary_Oct_k3_100
CoexpressionAtlasdev gonad_e13.5_F_DevVascOvary_Flk_k-means-cluster#4_top-relative-expression-ranked_200

ENPP3 PRDM1

7.46e-063342gudmap_dev gonad_e13.5_F_gudmap_devVascOvary_Flk_k4_200
CoexpressionAtlasdev gonad_e13.5_M_DevVasTestis_Flk_k-means-cluster#2_top-relative-expression-ranked_100

ENPP3 PRDM1

7.46e-063342gudmap_dev gonad_e13.5_M_gudmap_devVasTestis_Flk_k2_100
CoexpressionAtlasdev gonad_e12.5_F_DevVasOvary_Flk_k-means-cluster#2_top-relative-expression-ranked_200

ENPP3 PRDM1

7.46e-063342gudmap_dev gonad_e12.5_F_gudmap_devVasOvary_Flk_k2_200
CoexpressionAtlasdev gonad_e11.5_M_PrimGermCell_Oct_k-means-cluster#3_top-relative-expression-ranked_100

ENPP3 PRDM1

7.46e-063342gudmap_dev gonad_e11.5_M_PrimGermCell_Oct_k3_100
CoexpressionAtlasdev gonad_e12.5_F_DevVasOvary_Flk_k-means-cluster#2_top-relative-expression-ranked_100

ENPP3 PRDM1

7.46e-063342gudmap_dev gonad_e12.5_F_gudmap_devVasOvary_Flk_k2_100
CoexpressionAtlasdev gonad_e11.5_F_PrimGermCell_Oct_k-means-cluster#2_top-relative-expression-ranked_200

ENPP3 PRDM1

7.46e-063342gudmap_dev gonad_e11.5_F_PrimGermCell_Oct_k2_200
CoexpressionAtlasdev gonad_e11.5_M_PrimGermCell_Oct_k-means-cluster#1_top-relative-expression-ranked_200

ENPP3 PRDM1

7.46e-063342gudmap_dev gonad_e11.5_M_PrimGermCell_Oct_k1_200
CoexpressionAtlasdev gonad_e13.5_F_DevVascOvary_Flk_k-means-cluster#1_top-relative-expression-ranked_100

ENPP3 PRDM1

7.46e-063342gudmap_dev gonad_e13.5_F_gudmap_devVascOvary_Flk_k1_100
CoexpressionAtlasdev gonad_e12.5_M_DevVasTestis_Flk_k-means-cluster#4_top-relative-expression-ranked_100

ENPP3 PRDM1

1.49e-054342gudmap_dev gonad_e12.5_M_gudmap_devVasTestis_Flk_k4_100
CoexpressionAtlasdev gonad_e11.5_F_PrimGermCell_Oct_k-means-cluster#4_top-relative-expression-ranked_500

ENPP3 PRDM1

3.72e-056342gudmap_dev gonad_e11.5_F_PrimGermCell_Oct_k4_500
CoexpressionAtlasdev gonad_e11.5_F_ReproVasc_Flk_k-means-cluster#1_top-relative-expression-ranked_200

ENPP3 PRDM1

1.36e-0411342gudmap_dev gonad_e11.5_F_ReproVasc_Flk_k1_200
CoexpressionAtlasalpha beta T cells, T.4.Sp.B16, 4+ 8- TCR+ 45+, B16 Melanoma Spleen, avg-2

CTLA4 INPP4B PRDM1

1.91e-0470343GSM605761_100
CoexpressionAtlasalpha beta T cells, T.8.TI.B16, 4- 8+ TCR+ 45+, B16 Melanoma Tumor, avg-2

CTLA4 INPP4B PRDM1

2.34e-0475343GSM605773_100
CoexpressionAtlasdev gonad_e12.5_M_GermCellTestis_Oct_k-means-cluster#3_top-relative-expression-ranked_200

ENPP3 PRDM1

2.58e-0415342gudmap_dev gonad_e12.5_M_GermCellTestis_Oct_k3_200
CoexpressionAtlasdev gonad_e11.5_F_PrimGermCell_Oct_k-means-cluster#4_top-relative-expression-ranked_1000

ENPP3 PRDM1

4.18e-0419342gudmap_dev gonad_e11.5_F_PrimGermCell_Oct_k4_1000
CoexpressionAtlasdev gonad_e11.5_F_ReproVasc_Flk_k-means-cluster#2_top-relative-expression-ranked_500

ENPP3 PRDM1

5.13e-0421342gudmap_dev gonad_e11.5_F_ReproVasc_Flk_k2_500
CoexpressionAtlasdev gonad_e11.5_M_ReproVasc_Flk_k-means-cluster#1_top-relative-expression-ranked_500

ENPP3 PRDM1

6.72e-0424342gudmap_dev gonad_e11.5_M_ReproVasc_Flk_k1_500
ToppCellCV-Severe-6|CV / Virus stimulation, Condition and Cluster

CTLA4 DTX3L RBBP6 STAU1 PRDM1

4.91e-0719536569095c6ce2a7e763afa543c10d5710e0c3dda769
ToppCellfacs-Marrow-T_cells-18m-Lymphocytic-Klrb1a/b/c(-)_NK_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MMP25 CTLA4 INPP4B PRDM1

9.37e-06165364eeb58d4db64ad37dc6b441eab22b05c24862e1a9
ToppCelldroplet-Kidney-nan-21m-Lymphocytic-nan|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CTLA4 ST6GALNAC6 INPP4B PRDM1

1.21e-05176364feafc757e7aa4f17128ff34886beb2fd3461c9ea
ToppCellAdult-Immune-T_lymphocyte-D122|Adult / Lineage, Cell type, age group and donor

MMP25 CTLA4 INPP4B PRDM1

1.32e-0518036406c371d0f0c5a7b234dd143e98800e19af95a8b5
ToppCellControl-Control-Lymphocyte-T/NK-CD4+_T_activated|Control / Disease, condition lineage and cell class

PARD3B DTX3L ZCCHC2 INPP4B

1.92e-05198364ee71543559836fd59adc0da877b2ca538cba60cb
ToppCellCOVID-19|World / Disease, condition lineage and cell class

ARID1B ZCCHC2 RBBP6 SON

2.00e-052003647dec470c379cd89f05a0f37c8628b21f136e52f0
ToppCellmild|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

ARID1B DTX3L ZCCHC2 SON

2.00e-0520036412f1685ce8f218433068e090c9d839cd5a1910bf
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW19-Neuronal-Intermediate|GW19 / Sample Type, Dataset, Time_group, and Cell type.

PAPPA2 RADX ANKEF1

1.24e-04120363eb5b88c47dd4a6f9b55ace24f19d4e81d4ed31e1
ToppCellLPS-IL1RA-Hematopoietic_Mast-Mast_cells|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

MMP25 ENPP3 INPP4B

2.04e-041423632a9a070e7c53ac593d46c6c5f6983f07d4413501
ToppCellLPS-IL1RA-Hematopoietic_Mast|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

MMP25 ENPP3 INPP4B

2.04e-04142363f7d0d5ca9fc3dd929d4fdd59b71bfa623007e992
ToppCellLPS-IL1RA+antiTNF-Hematopoietic_Mast-Mast_cells|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

MMP25 ENPP3 INPP4B

2.21e-04146363a5c84ad44d6ffb25028a4fd5454fd5de81b16a5e
ToppCellLPS-IL1RA+antiTNF-Hematopoietic_Mast|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

MMP25 ENPP3 INPP4B

2.21e-041463638133037881c15e75637fc616091a7055488dd5fc
ToppCell367C-Lymphocytic-CD4_T-cell-Treg_cell_1|367C / Donor, Lineage, Cell class and subclass (all cells)

CTLA4 AJM1 INPP4B

2.25e-0414736347544227faf9b0f107bcf6be92b5f423b50c8e92
ToppCellLPS-antiTNF-Hematopoietic_Mast-Mast_cells|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

MMP25 ENPP3 INPP4B

2.35e-0414936359aa1f2a5cbeba64c4529fb05f544db17fd8b188
ToppCellLPS-antiTNF-Hematopoietic_Mast|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

MMP25 ENPP3 INPP4B

2.35e-041493631527cdd98a2734cbf8ce4c6170557280b71c55cb
ToppCellsevere_influenza-Treg|World / disease group, cell group and cell class (v2)

CTLA4 ENPP3 PRDM1

2.35e-041493632a3a00cdf604c8f3f3863df0ddb06938549bf86d
ToppCellLPS_only-Hematopoietic_Mast-Mast_cells|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

MMP25 ENPP3 INPP4B

2.39e-041503637290e9a812b1b2f919e67ccde0acf52687ab138f
ToppCellLPS_only-Hematopoietic_Mast|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

MMP25 ENPP3 INPP4B

2.39e-041503632c5078a1f769ba8153dee756b53d28eb7b434a96
ToppCell3'_v3-Lung-Lymphocytic_T_CD4-T_CD4/CD8|Lung / Manually curated celltypes from each tissue

PAPPA2 INPP4B PRDM1

2.44e-04151363999c11d19b61d6b130ad5e623afa83cbdfe13cdd
ToppCellPBMC-Control-Lymphocyte-T/NK-CD4+_T-Treg-Treg_4|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

PARD3B CTLA4 TMEM68

2.68e-0415636384f01419d8c116714e8c8c857c4d153a755b7867
ToppCellVE-Treg-naive_CD4|VE / Condition, Cell_class and T cell subcluster

CTLA4 NIPSNAP1 STAU1

2.68e-041563636501baf73616e702946de9fb13d267e30a68888b
ToppCellPBMC-Control-Lymphocyte-T/NK-CD4+_T-Treg-Treg_4|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

PARD3B CTLA4 TMEM68

2.68e-041563632285be9746d0d0f62a488b9c64fa67a834758dd7
ToppCell367C-Lymphocytic-CD4_T-cell-Treg_cell_2|367C / Donor, Lineage, Cell class and subclass (all cells)

CTLA4 RADX PRDM1

2.73e-04157363f1c6c313836352271033d23efd31b0f0a8a09e02
ToppCellHealthy/Control-Treg|Healthy/Control / Disease group and Cell class

PARD3B CTLA4 PRDM1

2.84e-0415936316a322760c99f3e2c3b73cbb399f77868951d3cb
ToppCellURO-Lymphocyte-T_NK-CD4_TEM|URO / Disease, Lineage and Cell Type

INPP4B PRODH PRDM1

2.89e-04160363e406f77b1c1a01d74f39ba65f99d5f8c7d75faf1
ToppCellHealthy_Control-Myeloid-Macrophages-|Healthy_Control / Condition, Lineage, Cell class and cell subclass

CTLA4 INPP4B PRDM1

2.94e-04161363d0482666479530cd2fd0d229cbb59a1d79839477
ToppCellHealthy/Control-Treg|World / Disease group and Cell class

PARD3B CTLA4 PRDM1

2.94e-04161363457297cda5c9cee3bcc069fdecbbe24def027e5f
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c04-ANXA2|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

CTLA4 INPP4B PRDM1

3.11e-041643638f3255d7f67890389a768453492243ea982eb38a
ToppCellfacs-Lung-EPCAM-24m-Lymphocytic-Ly6g5b+_T|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MMP25 CTLA4 MSLNL

3.11e-041643634e1861382c9e93856da19303474c8975c19706d2
ToppCellfacs-Lung-EPCAM-24m-Lymphocytic-T_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MMP25 CTLA4 MSLNL

3.11e-04164363467ad12884b70d243988174ae960ee2b7b6cfb0c
ToppCellPBMC-Severe-Lymphocyte-T/NK-CD4+_T-Treg-Treg_4|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

CTLA4 INPP4B PRDM1

3.16e-041653634edc9714185a7519a7044487a3d6ea845131b851
ToppCell10x5'-bone_marrow-Lymphocytic_T_CD4-Tregs|bone_marrow / Manually curated celltypes from each tissue

CTLA4 INPP4B PRDM1

3.16e-041653631ae1ad4e1fe19b6eefff0f9a03d58a384f169759
ToppCellPBMC-Severe-Lymphocyte-T/NK-CD4+_T-Treg-Treg_4|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

CTLA4 INPP4B PRDM1

3.16e-04165363fd1d38b97564c1f64f5c7246dcec96d60364b7b2
ToppCellfacs-Lung-24m-Hematologic-lymphocytic-immature_innate_lymphoid_cell|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

MMP25 CTLA4 MSLNL

3.28e-041673635d1919bea8e5a52ac6fc953caff15509b7142923
ToppCellfacs-Lung-24m-Hematologic-lymphocytic-immature_innate_lymphoid_cell-Ly6g5b+_T|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

MMP25 CTLA4 MSLNL

3.28e-04167363d8f497860d48342a3aaaad328f88e4d55ab4faeb
ToppCell10x_3'_v2v3-Non-neoplastic-Lymphoid-CD4/CD8-Reg_T-E|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

KLHL11 CTLA4 PRDM1

3.34e-04168363187b98664843a304406f086ea696adbf32283d07
ToppCellsystemic_lupus_erythematosus-flare-Lymphocytic_T-CD4-positive,_alpha-beta_T_cell-male|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

INPP4B ANKEF1 PRODH

3.34e-041683635e721268f0baa51d3f640f7f4c41db769ebef210
ToppCell356C-Lymphocytic-CD4_T-cell-CD4+_Effector_T_cell-2|356C / Donor, Lineage, Cell class and subclass (all cells)

CTLA4 INPP4B PRDM1

3.34e-041683639d6ca10c272aea28082c09d469940f7232f6461c
ToppCell10x_3'_v3-tissue-resident_(10x_3'_v3)-lymphocytic-T_lymphocytic-effector_CD4-positive,_alpha-beta_T_cell|tissue-resident_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

CTLA4 INPP4B PRDM1

3.34e-0416836307be11b6f0f37106e219692db5795c6dd32807c9
ToppCellnormal-na-Lymphocytic_T-T4_em-male|normal / PBMC cell types (v2) per disease, treatment status, and sex

CTLA4 INPP4B PRDM1

3.51e-0417136361318a7aaf3bd8bdd28f8a8614ab4fdf2964b3a3
ToppCell356C-Lymphocytic-CD4_T-cell-CD4+_Effector_T_cell-2|CD4_T-cell / Donor, Lineage, Cell class and subclass (all cells)

MMP25 CTLA4 PRDM1

3.51e-04171363bdd30100b74e012eec3090799c22635aa57fa91d
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-Degenerative_Endothelial_Cell-Degenerative_endothelial_cell_-_unspecif|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

KLHL11 AJM1 PRDM1

3.70e-041743634d8c4a7d8f4972da68cebe0a79eb1a14ec546121
ToppCellHealthy_donor-Treg|World / disease group, cell group and cell class (v2)

CTLA4 INPP4B PRDM1

3.70e-04174363dc3b06420b0ad9c7060571e7bf5714e028d598bf
ToppCellHealthy_donor-Treg|Healthy_donor / disease group, cell group and cell class (v2)

CTLA4 INPP4B PRDM1

3.70e-041743631d76921c8404b5be5fbe9f3157d53578033f2ad2
ToppCellfacs-Marrow-T_cells-18m|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CTLA4 INPP4B PRDM1

3.76e-04175363d3d574962c0a4a0d64db120320f0d04e11d2c9d8
ToppCellfacs-Marrow-T_cells|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CTLA4 INPP4B PRDM1

3.76e-041753634d77fade9ab87b79ac206d074b0e2ef8930c044e
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Lymphoid-CD4/CD8-CD4_rest|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

CTLA4 INPP4B PRDM1

3.76e-041753638269721389a3ce98681460e6393f2cff816eaa25
ToppCelldroplet-Lung-18m-Hematologic-lymphocytic-CD4-positive,_alpha-beta_T_cell-CD4-positive,_alpha-beta_T_cell_l21|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

KLHL11 CTLA4 INPP4B

3.76e-04175363e7b0eda141b638f1aad9938aaa76b1ce80171be9
ToppCell(1)_T_regulatory|World / Lung cell shreds - cell class (v4) and cell subclass (v4)

CTLA4 INPP4B PRDM1

3.88e-041773635cda56b10df1ee8971ce8470d52062e01b703a4e
ToppCellfacs-SCAT-Fat-18m-Lymphocytic-NK_cell|SCAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MMP25 CTLA4 INPP4B

3.88e-04177363be35bb178fbc149f8a12984c012d98b486325ba9
ToppCellfacs-SCAT-Fat-3m-Lymphocytic-NK_cell|SCAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MMP25 CTLA4 INPP4B

4.01e-041793636f657c7a227f860934d0dfec9b97d35fd2cedfd2
ToppCellfacs-Thymus-Thymus_Flowthrough-18m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CTLA4 DTX3L INPP4B

4.08e-04180363de87503d9caac3ebc80ab8090c1a9ee5a925b2a0
ToppCellCOPD-Lymphoid-T_Regulatory|World / Disease state, Lineage and Cell class

CTLA4 INPP4B PRDM1

4.08e-0418036351a12fbad5fa7bb12e6d616a02ff9b5141e2b063
ToppCellControl-Lymphoid-T_Regulatory|World / Disease state, Lineage and Cell class

CTLA4 INPP4B PRDM1

4.08e-0418036347036eee4c128fbb443d1fc767b4de5cced93f0e
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c03-ITGA4|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

CTLA4 INPP4B PRDM1

4.08e-04180363d9dae9db8e17f6990032ee6cfa8393fae4768ca5
ToppCell10x5'-Liver-Lymphocytic_T_CD4-T_CD4/CD8|Liver / Manually curated celltypes from each tissue

ARID1B RADX INPP4B

4.15e-04181363f2315414e714ac86211546a935660c4be6e85f1b
ToppCellfacs-Liver-Hepatocytes-24m-Epithelial|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ST6GALNAC6 ENPP3 PRODH

4.21e-04182363770ce9f3f4538d0181a0181543841bc964c68274
ToppCellControl-Lymphoid-T_Regulatory|Control / Disease state, Lineage and Cell class

CTLA4 INPP4B PRDM1

4.21e-0418236331bb838cc2900f3c9da9f835d79d557a08abb928
ToppCellfacs-GAT-Fat-3m-Lymphocytic-T_cell|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MMP25 RADX INPP4B

4.21e-04182363751bd3e3b49de961523e98197688a05c998c121a
ToppCellfacs-Liver-Hepatocytes-24m-Epithelial-nan|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ST6GALNAC6 ENPP3 PRODH

4.21e-0418236377ab860e2add49dad0c1ffbfc64278ad499dfbd5
ToppCellfacs-Liver-Hepatocytes-24m-Epithelial-hepatocyte|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ST6GALNAC6 ENPP3 PRODH

4.21e-041823634921c7d5687cc79f896b39753bb621d7e3d2972f
ToppCellCalu_3-infected|Calu_3 / Cell line, Condition and Strain

DTX3L ZCCHC2 RBBP6

4.28e-041833638f7f5000645f24f20a8d7700c4df1f8953a1780b
ToppCelldroplet-Kidney-KIDNEY-1m-Epithelial-Pecam____kidney_capillary_endothelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GBX1 ST6GALNAC6 MSLNL

4.35e-041843631c857126c0ea0671f0d60b048efca288d348d653
ToppCellSmart-seq2-lymph_node_(Smart-seq2)-lymphocytic-T_lymphocytic|lymph_node_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

CTLA4 INPP4B PRDM1

4.42e-04185363115a74d0b9be580005d45d22d6e228801b2705e2
ToppCellIPF-Lymphoid-T_Regulatory|IPF / Disease state, Lineage and Cell class

CTLA4 INPP4B PRDM1

4.42e-04185363221cbd09d94cc0947d0e3c1aa14716d17cb2068d
ToppCellIPF-Lymphoid-T_Regulatory|World / Disease state, Lineage and Cell class

CTLA4 INPP4B PRDM1

4.42e-0418536377fbecdab10bacc005b1c7e22ca414cfecef13c1
ToppCellCOPD-Lymphoid-T_Regulatory|COPD / Disease state, Lineage and Cell class

CTLA4 INPP4B PRDM1

4.42e-04185363846403edd4c8f646201d519055198fc38b7ffff9
ToppCellpdx-Tumor_cells-T0|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)

PARD3B ANKEF1 NIPSNAP1

4.42e-041853631d874608aa2062024323512f68889219471b2f00
ToppCellNK-T_cells|World / lung cells shred on cell class, cell subclass, sample id

CTLA4 INPP4B PRDM1

4.49e-04186363279ab91ebca37a39b8907409e07f8b533df67542
ToppCellFrontal_cortex-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Sst-Inhibitory_Neuron.Gad1Gad2.Sst-Pdyn_(MGE-derived_cortical_interneurons--Martinotti_cells)-|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

PLA2G12B PRDM1

4.53e-043936266fe368f1dfe665c661cf9baf854d12eb28c25b8
ToppCellFrontal_cortex-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Sst-Inhibitory_Neuron.Gad1Gad2.Sst-Pdyn_(MGE-derived_cortical_interneurons--Martinotti_cells)|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

PLA2G12B PRDM1

4.53e-0439362d5b0bcdfb27c881049178079c48deb587a0b2fda
ToppCell3'_v3-bone_marrow-Lymphocytic_T_CD4-Tregs|bone_marrow / Manually curated celltypes from each tissue

CTLA4 INPP4B PRDM1

4.56e-04187363bda716a64262325e6e68b281caf131f1840fd298
ToppCellPBMC_fresh-frozen-Mild-Moderate_convalescent_d36-51-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c07-AHNAK|Mild-Moderate_convalescent_d36-51 / Compartment, severity and other cell annotations on 10x 3' data (130k)

RADX INPP4B PRDM1

4.63e-041883633e3055dacc05a932f2beb114babf1dc76994e1af
ToppCellCF-Lymphoid-T_cell_&_NK_cell|Lymphoid / Disease state, Lineage and Cell class

CTLA4 INPP4B PRDM1

4.63e-0418836315057036b46c9df621ec4955aa94ca3036245d45
ToppCellChildren_(3_yrs)-Immune-T_lymphocyte-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

CTLA4 INPP4B PRDM1

4.70e-04189363df30478b288084a1bd48f660409dcc784040897c
ToppCell(1)_T_CD4|World / Lung cell shreds - cell class (v4) and cell subclass (v4)

CTLA4 INPP4B PRDM1

4.70e-041893632298a96c53c5bd767e17554c50379b2d1ad8b5b0
ToppCell(1)_T_cells|World / Lung cell shreds - cell class (v4) and cell subclass (v4)

CTLA4 INPP4B PRDM1

4.70e-04189363fa6b85676b2b61483ae27720d0715dbfcbcfbdf9
ToppCellSevere-B_activate-7|Severe / disease group and sub_cluster of B and Plasma cells(res = 0.5)

DTX3L ZCCHC2 MMP17

4.78e-0419036367e6c8a5a8724bdf2861fd76a711319dfc71d47a
ToppCellnormal-na-Lymphocytic_T-T4_reg|normal / PBMC cell types (v2) per disease, treatment status, and sex

CTLA4 INPP4B PRDM1

4.78e-04190363b8897c3e0fe8bb7efaf6a3787104d454d81a4c92
ToppCellIPF-Lymphoid-T|IPF / Disease state, Lineage and Cell class

CTLA4 INPP4B PRDM1

4.78e-04190363d57df208aaf7a5554899bb9107c80b443fd0cf93
ToppCellnormal-na-Lymphocytic_T-T4_reg-female|normal / PBMC cell types (v2) per disease, treatment status, and sex

CTLA4 INPP4B PRDM1

4.78e-04190363d8c1998eb02d5105598608d4733b63978ffa3eb2
ToppCellCTRL-Lymphoid-T_cell_&_NK_cell|Lymphoid / Disease state, Lineage and Cell class

CTLA4 INPP4B PRDM1

4.85e-0419136332381d353e40bce77a5b63c7bdbe360d27327d86
ToppCellCalu_3-infected-SARSCoV2|infected / Cell line, Condition and Strain

DTX3L ZCCHC2 RBBP6

4.85e-041913632da876d26f37a00dbdf1ee79d724306e8b20f304
ToppCellPBMC_fresh-frozen-Mild-Moderate_convalescent_d36-51-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c09-GZMK-FOS_l|Mild-Moderate_convalescent_d36-51 / Compartment, severity and other cell annotations on 10x 3' data (130k)

CTLA4 INPP4B PRDM1

4.85e-041913634a29b7d5cd10e9077699d3aa76e3db6c4d5a0cf6
ToppCellPBMC_fresh-frozen-Severe-critical_convalescent_d42-56-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c09-GZMK-FOS_l|Severe-critical_convalescent_d42-56 / Compartment, severity and other cell annotations on 10x 3' data (130k)

CTLA4 INPP4B PRDM1

4.85e-04191363b9ef6d82b86271b7e0875a399bb9aae84ef5bad3
ToppCell3'_v3-Lung-Lymphocytic_T_CD4|Lung / Manually curated celltypes from each tissue

CTLA4 INPP4B PRDM1

4.92e-04192363fd19cd0b5330448bef8debd753285adbc8b958a2
ToppCellControl-Lymphoid-T|World / Disease state, Lineage and Cell class

CTLA4 INPP4B PRDM1

4.92e-04192363253cf4d2cf88ad8c45b73779336180840bef054b
ToppCellHealthy_Control-Lymphoid-T-CCR7+_T|Healthy_Control / Condition, Lineage, Cell class and cell subclass

CTLA4 INPP4B PRDM1

4.92e-041923635b197f65a87c315e4f50c77a7fdec3b342a863ad
ToppCelldistal-1-Hematologic-CD4+_Memory/Effector_T|1 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

CTLA4 INPP4B PRDM1

4.92e-04192363e2611de161d629d901765ca0e4db75bb65096a25
ToppCellCOPD-Lymphoid-T|World / Disease state, Lineage and Cell class

CTLA4 INPP4B PRDM1

4.92e-04192363eb4909574fb5fc91399463523e2737095773200a
ToppCellHealthy-Treg|Healthy / disease group, cell group and cell class

CTLA4 INPP4B PRDM1

4.92e-041923639d3795a64bf0c62f460d80730c5615869fc46933
ToppCellIPF-Lymphoid-T|World / Disease state, Lineage and Cell class

CTLA4 INPP4B PRDM1

4.92e-04192363b25ba1f3bc842c22602b2aeed3b1b5082863e4fa
ToppCellASK428-Immune-T_cell|ASK428 / Donor, Lineage and Cell class of Lung cells from Dropseq

CTLA4 INPP4B PRDM1

4.92e-04192363121cb8c61002f20e1d287b8a7e67a30bb163e74a
ToppCell367C-Lymphocytic-CD4_T-cell|367C / Donor, Lineage, Cell class and subclass (all cells)

CTLA4 INPP4B PRDM1

4.92e-041923637181174ea95abbeb6628d992b4fbae2f2af5edc6
ToppCellCV-Healthy-1|Healthy / Virus stimulation, Condition and Cluster

DTX3L INPP4B PRDM1

4.92e-041923632a2052b44e8f679ef484f03ba4fb37b0ec841b88
ToppCellASK454-Immune-T_cell|ASK454 / Donor, Lineage and Cell class of Lung cells from Dropseq

CTLA4 INPP4B PRDM1

5.00e-0419336327c38a364bcdb4c0967155f18aa81d37e17c920b
ToppCellHealthy-Treg|World / disease group, cell group and cell class

CTLA4 INPP4B PRDM1

5.00e-04193363e22bfcd170ba23e313512f0f07c658fcf6ae1b97
ToppCellASK428-Immune-T_cell|Immune / Donor, Lineage and Cell class of Lung cells from Dropseq

CTLA4 INPP4B PRDM1

5.00e-04193363bca9bf941193feea8ed56735041513185c165135
ToppCellControl-Lymphoid-T|Control / Disease state, Lineage and Cell class

CTLA4 INPP4B PRDM1

5.00e-04193363af928046ccd1ca874be1534aef6ca7f27d90bc46
ToppCellInfluenza_Severe-CD8+_Tem|World / Disease group and Cell class

AJM1 INPP4B PRDM1

5.00e-04193363fce6138712353fba14eb046e10d54e112372658e
Diseasediffuse large B-cell lymphoma (is_marker_for)

DICER1 PRDM1

3.38e-058332DOID:0050745 (is_marker_for)
Diseasecolorectal cancer (is_marker_for)

LATS2 DICER1 PRDM1

7.17e-04157333DOID:9256 (is_marker_for)
DiseaseBreast adenocarcinoma

ARID1B INPP4B

9.68e-0441332C0858252
DiseaseNeoplasm of uncertain or unknown behavior of breast

ARID1B INPP4B

9.68e-0441332C0496956
Diseasehepatocellular carcinoma (is_implicated_in)

CTLA4 DICER1 PRDM1

1.08e-03181333DOID:684 (is_implicated_in)
DiseaseLibman-Sacks Disease

CTLA4 PRDM1

1.93e-0358332C0242380
DiseaseLupus Erythematosus, Systemic

CTLA4 PRDM1

2.87e-0371332C0024141
Diseasetonsillectomy risk measurement

PARD3B CTLA4 NIPSNAP1

3.03e-03260333EFO_0007924
Diseasecancer (implicated_via_orthology)

ARID1B LATS2 RBBP6

3.30e-03268333DOID:162 (implicated_via_orthology)

Protein segments in the cluster

PeptideGeneStartEntry
GEAPRAYGLPYGPRY

AJM1

346

C9J069
YAFPRRQDGGPPYYM

ANKEF1

441

Q9NU02
GQYPYPYSRERMQGP

ARID1B

1491

Q8NFD5
YPRPDQPCYLYVIGM

DICER1

761

Q9UPY3
MVIGGYYPYPPVPET

RADX

501

Q6NSI4
TYGGVLYKPPPQRMF

ABCD1

526

P33897
MRPFYQGPVGDPDKY

MMP25

251

Q9NPA2
PRGLYKERELPYYPG

PARD3B

1101

Q8TEW8
LRYPPGYFPRDNLRM

MBTPS1

631

Q14703
EMPRPYVDYLFPGVG

LATS2

206

Q9NRM7
MAFPKYYRPPEGTYG

INPP4B

906

O15327
YYGPLIFMYLRPASP

OR5H2

256

Q8NGV7
RPQYQRFMRDNYPPG

FUCA1

86

P04066
AYYRLMRPYLGGSPG

MSLNL

491

Q96KJ4
YRCRYGKAPMPRPGY

PLA2G12B

66

Q9BX93
EVPPPYDMKAYYGRS

RBBP6

801

Q7Z6E9
YPSRAGNYLRPYPVG

PAPPA2

71

Q9BXP8
YTGYPMFMPYRPVVL

GBX2

41

P52951
LLYTGYPMFMPYRPL

GBX1

41

Q14549
IPYRYLHGTQRYPMP

KLHL11

661

Q9NVR0
PEMYGYPDPSYLKRV

DTX3L

716

Q8TDB6
PRINFFYMYEGPAPR

ENPP3

391

O14638
VELMYPPPYYLGIGN

CTLA4

131

P16410
PQPRMGPNIYELRTY

NIPSNAP1

176

Q9BPW8
LRYKGPGFEYFSPMP

RPUSD2

521

Q8IZ73
MRPYYQGPVGDPLRY

MMP17

266

Q9ULZ9
AGYPVYKYVPYGPVM

PRODH

541

O43272
LQRMPYHYYEPKGPD

ST6GALNAC6

276

Q969X2
RGSPEMPFYPRVVYP

PRDM1

286

O75626
SYYYPNPMPGPMYRV

ZCCHC2

1031

Q9C0B9
YPFAPMYGGFPVKLR

TMEM68

261

Q96MH6
NMRGGAYPPRYFYPF

STAU1

106

O95793
YVVRGPEMTPYEGGY

UBE2J2

46

Q8N2K1
NRYYVPYGGPRPESY

TREH

276

O43280
YRLTPDPYRMSPRPY

SON

956

P18583
KYSPENFPYRRGPGM

TBCEL

16

Q5QJ74