Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyBiologicalProcesscilium assembly

FLNA B3GLCT OFD1 CEP162 SYNE1 CILK1 DNAI3 CFAP65 TBC1D8 ALMS1 CC2D2A CPLANE1 HYDIN

9.96e-0644413913GO:0060271
GeneOntologyBiologicalProcessSertoli cell development

SOX9 FLNA FER IL1A

1.89e-05241394GO:0060009
GeneOntologyBiologicalProcesscilium organization

FLNA B3GLCT OFD1 CEP162 SYNE1 CILK1 DNAI3 CFAP65 TBC1D8 ALMS1 CC2D2A CPLANE1 HYDIN

2.08e-0547613913GO:0044782
GeneOntologyBiologicalProcessorganelle assembly

FLNA B3GLCT NRAP OFD1 CEP162 SYNE1 CILK1 SPG11 DNAI3 DICER1 CFAP65 TBC1D8 MDN1 ALMS1 BRCA1 PRRC2C CC2D2A NLGN2 WDR1 CPLANE1 HYDIN

2.49e-05113813921GO:0070925
GeneOntologyBiologicalProcessheart development

PCSK5 SOX9 FLNA FAT4 NRAP SYNE1 BCOR ECE1 DICER1 TENM4 LRP1 CC2D2A ROBO2 LTBP1 IL1A CPLANE1

5.23e-0575713916GO:0007507
GeneOntologyBiologicalProcessSertoli cell differentiation

SOX9 FLNA FER IL1A

6.94e-05331394GO:0060008
GeneOntologyBiologicalProcesscell-cell adhesion

SOX9 RAG1 FLNA DCHS2 FAT4 METTL3 DSG1 PCDHB12 PCDHB11 NFASC FAT2 TENM4 FER DLG2 ROBO2 ASTN1 NLGN2 IL1A CD200

1.14e-04107713919GO:0098609
GeneOntologyCellularComponentdimeric IgA immunoglobulin complex

IGHA1 IGHA2

1.43e-0431452GO:0071750
GeneOntologyCellularComponentsecretory dimeric IgA immunoglobulin complex

IGHA1 IGHA2

1.43e-0431452GO:0071752
HumanPhenoWide anterior fontanel

SOX9 FLNA FAT4 B3GLCT POR DICER1 SETBP1 LTBP1

1.01e-0599568HP:0000260
HumanPhenoAbnormal anterior fontanelle morphology

SOX9 FLNA FAT4 B3GLCT POR NFASC DICER1 SETBP1 LTBP1

1.38e-05136569HP:0000236
HumanPhenoAbnormal thumb morphology

SOX9 FLNA NPR3 B3GLCT OFD1 SYNE1 CILK1 BCOR ECE1 BRCA1 SETBP1 CC2D2A CPLANE1 KAT6B ALG13

2.11e-054085615HP:0001172
HumanPhenoShort toe

SOX9 RAG1 FLNA B3GLCT OFD1 TBL1XR1 ALMS1 ASCC3

3.24e-05116568HP:0001831
HumanPhenoAbnormal external nose morphology

SOX9 MARS2 FLNA B3GLCT OFD1 POR MPDZ CILK1 BCOR ECE1 TBL1XR1 DICER1 BRCA1 SETBP1 CC2D2A LTBP1 TAF4 ASCC3 CPLANE1 KAT6B DISP1 FOXG1 ALG13

4.21e-059165623HP:0010938
HumanPhenoAbnormal intestine morphology

MARS2 RAG1 FLNA FAT4 B3GLCT OFD1 DSG1 VPS13C SYNE1 POR SPG11 BCOR ECE1 DICER1 ALMS1 BRCA1 SETBP1 CC2D2A C1R LTBP1 TAF4 WDR1 ASCC3 CPLANE1 KAT6B HYDIN DISP1 FOXG1 DNMT1 TBL1X

7.13e-0514595630HP:0002242
HumanPhenoTibial bowing

SOX9 FLNA CILK1 SETBP1 CPLANE1

7.42e-0541565HP:0002982
HumanPhenoAnteriorly placed anus

FAT4 B3GLCT POR SETBP1 KAT6B DISP1

8.70e-0568566HP:0001545
HumanPhenoAbnormal nasal bridge morphology

SOX9 MARS2 FLNA FAT4 B3GLCT OFD1 SYNE1 POR CILK1 NFASC MDH1 BCOR ECE1 DICER1 BRCA1 SETBP1 CC2D2A LTBP1 TAF4 ASCC3 CPLANE1 KAT6B DISP1 FOXG1

8.99e-0510295624HP:0000422
HumanPhenoChoanal atresia or stenosis

SOX9 FAT4 OFD1 POR PTPN14 BRCA1 SETBP1 DISP1

9.12e-05134568HP:0000416
HumanPhenoAbnormal choanae morphology

SOX9 FAT4 OFD1 POR PTPN14 BRCA1 SETBP1 DISP1

9.12e-05134568HP:0000415
HumanPhenoAbnormal toe morphology

SOX9 RAG1 FLNA FAT4 NPR3 B3GLCT OFD1 MAT2A POR CILK1 BCOR ECE1 TBL1XR1 ALMS1 BRCA1 SETBP1 CC2D2A C1R TAF4 ASCC3 CPLANE1 KAT6B

9.20e-058935622HP:0001780
HumanPhenoAbnormal oral frenulum morphology

FLNA B3GLCT OFD1 SETBP1 TAF4 CPLANE1

1.02e-0470566HP:0000190
HumanPhenoAbnormal midface morphology

SOX9 FLNA FAT4 NPR3 B3GLCT SETD1B OFD1 POR CILK1 BCOR TBL1XR1 DICER1 SETBP1 LRP1 CC2D2A LTBP1 KAT6B ZBTB11 FOXG1

1.03e-047045619HP:0000309
HumanPhenoAplasia/Hypoplasia of toe

SOX9 RAG1 FLNA B3GLCT OFD1 TBL1XR1 ALMS1 ASCC3

1.24e-04140568HP:0001991
HumanPhenoAbnormal tibia morphology

SOX9 FLNA POR CILK1 SETBP1 TAF4 CPLANE1

1.47e-04107567HP:0002992
HumanPhenoAbnormal curvature of the vertebral column

SOX9 MARS2 FLNA FAT4 B3GLCT OFD1 MAT2A SYNE1 POR SPG11 BCOR TBL1XR1 DICER1 ALMS1 BRCA1 SETBP1 CC2D2A C1R LTBP1 TAF4 ASCC3 CPLANE1 KAT6B DISP1 FOXG1 ALG13

1.80e-0412195626HP:0010674
HumanPhenoHypoplasia of olfactory tract

SOX9 OFD1 CPLANE1

1.95e-0411563HP:0007036
HumanPhenoAbnormal cheek morphology

FLNA FAT4 B3GLCT SETD1B BCOR TBL1XR1 DICER1 LRP1 CC2D2A LTBP1 KAT6B

1.96e-042825611HP:0004426
HumanPhenoAbnormal nasal tip morphology

FLNA OFD1 POR MPDZ CILK1 BCOR ECE1 TBL1XR1 SETBP1 LTBP1 CPLANE1 KAT6B FOXG1

2.07e-043865613HP:0000436
HumanPhenoShort palpebral fissure

SOX9 FAT4 B3GLCT BRCA1 SETBP1 TAF4 KAT6B

3.33e-04122567HP:0012745
HumanPhenoAbnormal cerebral ventricle morphology

SOX9 MARS2 FLNA FAT4 B3GLCT OFD1 POR MPDZ CILK1 SPG11 BCOR TBL1XR1 BRCA1 ATXN1 SETBP1 CC2D2A CPLANE1 KAT6B ZBTB11 HYDIN DISP1 DNMT1 ALG13

3.49e-0410465623HP:0002118
HumanPhenoChoanal atresia

SOX9 FAT4 OFD1 POR PTPN14 BRCA1 DISP1

3.50e-04123567HP:0000453
HumanPhenoScoliosis

SOX9 MARS2 FLNA FAT4 B3GLCT OFD1 MAT2A SYNE1 POR SPG11 BCOR TBL1XR1 ALMS1 BRCA1 SETBP1 CC2D2A C1R LTBP1 TAF4 CPLANE1 KAT6B DISP1 FOXG1 ALG13

3.67e-0411225624HP:0002650
HumanPhenoAbnormal upper lip morphology

SOX9 MARS2 FLNA FAT4 B3GLCT OFD1 SYNE1 POR CILK1 BCOR TBL1XR1 BRCA1 SETBP1 CC2D2A LTBP1 TAF4 ASCC3 CPLANE1 KAT6B DISP1 FOXG1 ALG13

3.75e-049805622HP:0000177
MousePhenopersistent truncus arteriosus

PCSK5 FLNA ECE1 CC2D2A LTBP1 CPLANE1

1.07e-05671056MP:0002633
MousePhenoabnormal aorticopulmonary septum morphology

PCSK5 FLNA ECE1 CC2D2A LTBP1 CPLANE1

1.17e-05681056MP:0010650
MousePhenoaorticopulmonary septal defect

PCSK5 FLNA ECE1 CC2D2A LTBP1 CPLANE1

1.17e-05681056MP:0010651
MousePhenoabnormal truncus arteriosus septation

PCSK5 FLNA ECE1 CC2D2A LTBP1 CPLANE1

3.93e-05841056MP:0010454
MousePhenoabnormal cardiac outflow tract development

PCSK5 FLNA POR ECE1 CC2D2A LTBP1 CPLANE1

6.63e-051341057MP:0006126
MousePhenohearing/vestibular/ear phenotype

NCOA2 SOX9 RAG1 FAT4 NPR3 MPDZ ZMAT4 ECE1 TBL1XR1 ALMS1 PRRC2C ATAD2B TMPRSS3 PTPRQ FER CC2D2A WDR1 KAT6B

1.28e-0490510518MP:0005377
MousePhenoabnormal interatrial septum morphology

PCSK5 FLNA FAT4 CC2D2A LTBP1 CPLANE1

1.52e-041071056MP:0000282
DomainEGF

PCSK5 FAT4 ADAM23 FAT2 OIT3 TENM4 LRP1 C1R ASTN1 LTBP1

1.45e-0523514410SM00181
DomainEGF-like_dom

PCSK5 FAT4 ADAM23 FAT2 OIT3 TENM4 LRP1 C1R ASTN1 LTBP1

2.38e-0524914410IPR000742
DomainLisH

OFD1 TBL1XR1 TBL1X

3.64e-0591443PF08513
DomainZnf_C2H2-like

RAG1 OVOL3 ZMAT4 ZNF581 GPATCH8 ZNF229 ZNF19 ZNF605 ZNF37A ZFR ZNF84 ZNF841 ZNF606 ZBTB11 ZNF160 ZNF844 ZNF512 ZMAT1

4.19e-0579614418IPR015880
DomainZnF_C2H2

RAG1 OVOL3 ZMAT4 ZNF581 GPATCH8 ZNF229 ZNF19 ZNF605 ZNF37A ZFR ZNF84 ZNF841 ZNF606 ZBTB11 ZNF160 ZNF844 ZNF512 ZMAT1

5.08e-0580814418SM00355
DomainEGF_3

FAT4 ADAM23 FAT2 OIT3 TENM4 LRP1 C1R ASTN1 LTBP1

8.85e-052351449PS50026
DomainZnf_C2H2

OVOL3 ZMAT4 ZNF581 GPATCH8 ZNF229 ZNF19 ZNF605 ZNF37A ZFR ZNF84 ZNF841 ZNF606 ZBTB11 ZNF160 ZNF844 ZNF512 ZMAT1

1.59e-0480514417IPR007087
DomainEGF_1

FAT4 ADAM23 FAT2 OIT3 TENM4 LRP1 C1R ASTN1 LTBP1

1.64e-042551449PS00022
DomainAXH

HBP1 ATXN1

1.76e-0431442SM00536
DomainAXH

HBP1 ATXN1

1.76e-0431442PF08517
DomainAtaxin_AXH_dom

HBP1 ATXN1

1.76e-0431442IPR003652
DomainAXH

HBP1 ATXN1

1.76e-0431442PS51148
DomainCadherin_CS

DCHS2 FAT4 DSG1 PCDHB12 PCDHB11 FAT2

2.00e-041091446IPR020894
DomainEGF_2

FAT4 ADAM23 FAT2 OIT3 TENM4 LRP1 C1R ASTN1 LTBP1

2.19e-042651449PS01186
DomainCADHERIN_1

DCHS2 FAT4 DSG1 PCDHB12 PCDHB11 FAT2

2.43e-041131446PS00232
DomainCadherin

DCHS2 FAT4 DSG1 PCDHB12 PCDHB11 FAT2

2.43e-041131446PF00028
DomainCADHERIN_2

DCHS2 FAT4 DSG1 PCDHB12 PCDHB11 FAT2

2.55e-041141446PS50268
Domain-

DCHS2 FAT4 DSG1 PCDHB12 PCDHB11 FAT2

2.55e-0411414462.60.40.60
DomainCA

DCHS2 FAT4 DSG1 PCDHB12 PCDHB11 FAT2

2.67e-041151446SM00112
DomainCadherin-like

DCHS2 FAT4 DSG1 PCDHB12 PCDHB11 FAT2

2.80e-041161446IPR015919
DomainPropept_inh

CPA4 PCSK5 TPP1

2.82e-04171443IPR009020
DomainCadherin

DCHS2 FAT4 DSG1 PCDHB12 PCDHB11 FAT2

3.07e-041181446IPR002126
DomainEGF_CA

FAT4 FAT2 OIT3 LRP1 C1R LTBP1

3.67e-041221446SM00179
DomainEGF-like_Ca-bd_dom

FAT4 FAT2 OIT3 LRP1 C1R LTBP1

4.01e-041241446IPR001881
DomainSortilin_C

SORCS1 SORT1

5.81e-0451442PF15901
DomainSortilin-Vps10

SORCS1 SORT1

5.81e-0451442PF15902
DomainVPS10

SORCS1 SORT1

5.81e-0451442IPR006581
DomainSortilin_N

SORCS1 SORT1

5.81e-0451442IPR031778
DomainSortilin_C

SORCS1 SORT1

5.81e-0451442IPR031777
DomainVPS10

SORCS1 SORT1

5.81e-0451442SM00602
DomainZnf_C2H2_jaz

ZMAT4 GPATCH8 ZFR

6.21e-04221443IPR022755
Domainzf-C2H2_jaz

ZMAT4 GPATCH8 ZFR

6.21e-04221443PF12171
DomainEGF_Ca-bd_CS

FAT4 OIT3 LRP1 C1R LTBP1

9.27e-04971445IPR018097
DomainEGF-like_CS

FAT4 ADAM23 FAT2 TENM4 LRP1 C1R ASTN1 LTBP1

9.59e-042611448IPR013032
DomainZINC_FINGER_C2H2_1

OVOL3 ZNF581 GPATCH8 ZNF229 ZNF19 ZNF605 ZNF37A ZFR ZNF84 ZNF841 ZNF606 ZBTB11 ZNF160 ZNF844 ZNF512

9.87e-0477714415PS00028
DomainEGF_CA

FAT4 OIT3 LRP1 C1R LTBP1

1.02e-03991445PS01187
DomainASX_HYDROXYL

FAT4 OIT3 LRP1 C1R LTBP1

1.06e-031001445PS00010
DomainLisH

OFD1 TBL1XR1 TBL1X

1.28e-03281443IPR006594
DomainLisH

OFD1 TBL1XR1 TBL1X

1.28e-03281443SM00667
DomainLISH

OFD1 TBL1XR1 TBL1X

1.28e-03281443PS50896
DomainEGF-type_Asp/Asn_hydroxyl_site

FAT4 OIT3 LRP1 C1R LTBP1

1.38e-031061445IPR000152
DomainZnf_U1

ZMAT4 ZFR ZMAT1

1.42e-03291443IPR003604
DomainZnF_U1

ZMAT4 ZFR ZMAT1

1.42e-03291443SM00451
DomainPapD-like

CFAP65 HYDIN

2.05e-0391442IPR008962
Pubmed

Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.

NCOA2 KIF21B LSG1 SYNE1 MPDZ NFASC NOL9 BCOR TBL1XR1 FAM171A1 FRY MDN1 PRRC2C LRP1 DLG2 ZFR NLGN2 TAF4 WDR1 FOXG1 DNMT1 TBL1X

1.96e-109631502228671696
Pubmed

Hdac4 Interactions in Huntington's Disease Viewed Through the Prism of Multiomics.

CABLES2 SETD1B DSG1 LSG1 MPDZ DHX57 MDH1 TBL1XR1 FRY TENM4 PRRC2C FER ZFR DNMT1

2.15e-084751501431040226
Pubmed

Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.

NCOA2 SOX9 DCHS2 ADAM23 MAT2A SYNE1 TFIP11 MDH1 DGLUCY FRY ZNF605 TPP1 OSBPL1A LRP1 DLG2 ASTN1 ZNF84 ZNF841 ZNF606 ZBTB11 DNMT1

1.70e-0712851502135914814
Pubmed

In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.

CYLC1 FLNA ADAP1 LSG1 SYNE1 U2SURP DHX57 SPG11 ECE1 TNRC18 SF3B3 MDN1 BRCA1 PRRC2C CC2D2A DLG2 ZFR ISG20L2 ZNF84 TAF4 ZBTB11 DOP1A

2.72e-0714421502235575683
Pubmed

Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.

NCOA2 CABLES2 VPS13C CILK1 NFASC BCAR1 TBL1XR1 DNAH14 TNRC18 ATXN1 RALGPS1 SETBP1 LRP1 NLGN2 ZNF84 TAF4 ZSWIM4 KAT6B ZNF512 ZMAT1 DOP1A TBL1X

4.66e-0714891502228611215
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

KIF21B CEP162 VPS13C NFASC SPG11 BCOR DICER1 SF3B3 RALGPS1 SETBP1 ROBO2 AKAP11 KAT6B

5.55e-075291501314621295
Pubmed

Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.

FLNA U2SURP DHX57 NOL9 DICER1 MDN1 PRRC2C ATAD2B NOC4L ZFR ASCC3 ZBTB11 ZNF512 DNMT1

1.01e-066531501422586326
Pubmed

The STUbL RNF4 regulates protein group SUMOylation by targeting the SUMO conjugation machinery.

FLNA DSG1 LSG1 POR NFASC TFIP11 ZNF581 GPATCH8 CENPI LRP1 NOC4L CD151 WDR1 ZNF160 ZNF512 CENPVL1 PRAME HSDL1 FOXG1

1.15e-0612031501929180619
Pubmed

The ubiquitin-specific protease USP36 SUMOylates EXOSC10 and promotes the nucleolar RNA exosome function in rRNA processing.

FLNA MAT2A NOL12 U2SURP DHX57 NOL9 PRRC2C NOC4L ZFR ISG20L2 ZNF512 ALG13

1.37e-064831501236912080
Pubmed

Targeting TRIM37-driven centrosome dysfunction in 17q23-amplified breast cancer.

OFD1 DSG1 U2SURP BCOR SF3B3 ALMS1 ATXN1 LRP1

1.46e-06184150832908313
Pubmed

Improving GENCODE reference gene annotation using a high-stringency proteogenomics workflow.

CENPVL2 CENPVL3 CENPVL1

1.56e-066150327250503
Pubmed

Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.

CPA4 FLNA SETD1B DSG1 LSG1 MAT2A U2SURP DHX57 TFIP11 NOL9 PTPN14 SF3B3 MDN1 TPP1 ZFR PRPF38A WDR1 ASCC3 ZNF512 DNMT1

1.62e-0613531502029467282
Pubmed

The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.

METTL3 LSG1 SYNE1 MPDZ DHX57 TFIP11 NOL9 GPATCH8 RSRC2 BCOR TBL1XR1 DICER1 MDN1 BRCA1 TPP1 NOC4L ISG20L2 PRPF38A TAF4 ASCC3 ZBTB11

1.99e-0614971502131527615
Pubmed

Expression of mouse dchs1, fjx1, and fat-j suggests conservation of the planar cell polarity pathway identified in Drosophila.

DCHS2 FAT4 FAT2

2.72e-067150316059920
Pubmed

Interactomes of Glycogen Synthase Kinase-3 Isoforms.

OFD1 LSG1 MPDZ DICER1 TBC1D8 ALMS1 AKAP11 ASCC3

3.77e-06209150836779422
Pubmed

Global genetic analysis in mice unveils central role for cilia in congenital heart disease.

PCSK5 CXCL16 LRP1 CC2D2A LTBP1 CPLANE1

4.97e-06100150625807483
Pubmed

SRCAP complex promotes lung cancer progression by reprograming the oncogenic transcription of Hippo-YAP/TAZ signaling pathway.

NCOA2 FLNA MPDZ TFIP11 BCOR PTPN14 ALMS1 PRRC2C ZFR TAF4 ASCC3 DNMT1

5.10e-065491501238280479
Pubmed

Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein.

PCSK5 LSG1 MPDZ DHX57 TFIP11 NOL9 ECE1 DICER1 PRRC2C TPP1 ZBTB11 HSDL1 DNMT1

5.32e-066501501338777146
Pubmed

Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.

SYNE1 NFASC DICER1 TENM4 ALMS1 SETBP1 AKAP11 KAT6B

6.48e-06225150812168954
Pubmed

Prediction of the coding sequences of unidentified human genes. XX. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.

SPG11 TNRC18 ZNF606 ZNF512 ZMAT1 HYDIN

7.35e-06107150611347906
Pubmed

FBXO22 promotes leukemogenesis by targeting BACH1 in MLL-rearranged acute myeloid leukemia.

KIF21B DCHS2 U2SURP DHX57 TFIP11 SPG11 MDN1 ZFR TAF4 ASCC3 HYDIN

1.14e-054971501136774506
Pubmed

USP7 Regulates Cytokinesis through FBXO38 and KIF20B.

GPATCH8 BCOR BRCA1 NOC4L TAF4 DNMT1

1.17e-05116150630804394
Pubmed

Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.

MARS2 FLNA DSG1 LSG1 VPS13C MAT2A SYNE1 U2SURP POR NOL9 MDH1 DICER1 SF3B3 MDN1 CC2D2A NOC4L ZFR ZNF512 DNMT1

1.30e-0514251501930948266
Pubmed

A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration.

PCSK5 FAT4 HBP1 GPATCH8 RSRC2 BCOR BRCA1 ATXN1 ROBO2 LTBP1 KAT6B ALG13

1.41e-056081501216713569
Pubmed

Molecular characterization of DICER1-mutated pituitary blastoma.

DICER1 PRAME

1.85e-052150233644822
Pubmed

The AXH module: an independently folded domain common to ataxin-1 and HBP1.

HBP1 ATXN1

1.85e-052150212965213
Pubmed

TBL1X: At the crossroads of transcriptional and posttranscriptional regulation.

TBL1XR1 TBL1X

1.85e-052150236206873
Pubmed

Oncogenic fusion transcript analysis identified ADAP1-NOC4L, potentially associated with metastatic colorectal cancer.

ADAP1 NOC4L

1.85e-052150235702822
Pubmed

Dnmt1 deficiency promotes CAG repeat expansion in the mouse germline.

ATXN1 DNMT1

1.85e-052150218252747
Pubmed

Gout inheritance in an extended Chinese family analyzed by whole-exome sequencing: A case-report.

OIT3 LRP1

1.85e-052150232569156
Pubmed

The structure and function of human IgA.

IGHA1 IGHA2

1.85e-05215022241915
Pubmed

BRCA1 affects global DNA methylation through regulation of DNMT1.

BRCA1 DNMT1

1.85e-052150220820192
Pubmed

Andrographolide Induces Cell Cycle Arrest and Apoptosis of Chondrosarcoma by Targeting TCF-1/SOX9 Axis.

SOX9 HNF1A

1.85e-052150228485543
Pubmed

Clinically approved immunomodulators ameliorate behavioral changes in a mouse model of hereditary spastic paraplegia type 11.

RAG1 SPG11

1.85e-052150238435059
Pubmed

Identification of new human cadherin genes using a combination of protein motif search and gene finding methods.

DCHS2 FAT4

1.85e-052150215003449
Pubmed

BRCA1 deficiency in mature CD8+ T lymphocytes impairs antitumor immunity.

RAG1 BRCA1

1.85e-052150236731891
Pubmed

SUMOylation of TBL1 and TBLR1 promotes androgen-independent prostate cancer cell growth.

TBL1XR1 TBL1X

1.85e-052150227129164
Pubmed

Human sorCS1 binds sortilin and hampers its cellular functions.

SORCS1 SORT1

1.85e-052150224128306
Pubmed

Requirement for dicer in survival of proliferating thymocytes experiencing DNA double-strand breaks.

RAG1 DICER1

1.85e-052150223427252
Pubmed

ZNF606 interacts with Sox9 to regulate chondrocyte differentiation.

SOX9 ZNF606

1.85e-052150227634221
Pubmed

HBP1-mediated transcriptional regulation of DNA methyltransferase 1 and its impact on cell senescence.

HBP1 DNMT1

1.85e-052150223249948
Pubmed

Interaction network of human early embryonic transcription factors.

NCOA2 BCOR TBL1XR1 SORT1 TNRC18 ALMS1 ATXN1 TAF4 TBL1X

2.34e-05351150938297188
Pubmed

A central chaperone-like role for 14-3-3 proteins in human cells.

OFD1 LSG1 CEP162 MPDZ BCAR1 FAM171A1 PTPN14 MDN1 ALMS1 ATXN1 PRRC2C AKAP11 DOP1A DNMT1

2.34e-058611501436931259
Pubmed

Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.

OFD1 LSG1 SYNE1 POR MPDZ TFIP11 SPG11 NOL9 DICER1 TBC1D8 FAM171A1 PTPN14 SF3B3 MDN1 NOC4L AKAP11 ASCC3 ZNF512 DNMT1

2.34e-0514871501933957083
Pubmed

Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.

LSG1 NOL12 RSRC2 BCOR DICER1 PTPN14 SF3B3 ALMS1 BRCA1 ATXN1 LRP1 TAF4 ASCC3 KAT6B AGBL1 ALG13

2.79e-0511161501631753913
Pubmed

Human transcription factor protein interaction networks.

NCOA2 SOX9 HNF1A OFD1 TFIP11 GPATCH8 BCOR TBL1XR1 ALMS1 BRCA1 ATXN1 PRRC2C NOC4L ZFR TAF4 WDR1 ZNF512 TBL1X

4.70e-0514291501835140242
Pubmed

Loss of zinc-finger protein 212 leads to Purkinje cell death and locomotive abnormalities with phospholipase D3 downregulation.

ADAP1 FAT2 ATXN1 DNMT1

4.71e-0546150434815492
Pubmed

Interaction of LATS1 with SMAC links the MST2/Hippo pathway with apoptosis in an IAP-dependent manner.

DSG1 U2SURP NOL9 ALMS1 PTPRQ TAF4 ASCC3

5.34e-05222150735941108
Pubmed

A SOX9-B7x axis safeguards dedifferentiated tumor cells from immune surveillance to drive breast cancer progression.

SOX9 RAG1

5.53e-053150237963469
Pubmed

Normal DNA methylation dynamics in DICER1-deficient mouse embryonic stem cells.

DICER1 DNMT1

5.53e-053150222969435
Pubmed

An activated lck transgene promotes thymocyte development in RAG-1 mutant mice.

RAG1 CILK1

5.53e-05315027889413
Pubmed

EGFR Mutation Promotes Glioblastoma through Epigenome and Transcription Factor Network Remodeling.

SOX9 FOXG1

5.53e-053150226455392
Pubmed

Transient expression of SOX9 protein during follicular development in the adult mouse ovary.

SOX9 POR

5.53e-053150216488195
Pubmed

Combined immune checkpoint blockade as a therapeutic strategy for BRCA1-mutated breast cancer.

RAG1 BRCA1

5.53e-053150228592566
Pubmed

MicroRNA-155 drives TH17 immune response and tissue injury in experimental crescentic GN.

RAG1 DICER1

5.53e-053150223949802
Pubmed

Filamin-A fragment localizes to the nucleus to regulate androgen receptor and coactivator functions.

NCOA2 FLNA

5.53e-053150212682292
Pubmed

Establishment of tumor-associated immunity requires interaction of heat shock proteins with CD91.

RAG1 LRP1

5.53e-053150224778318
Pubmed

TRIM44 promotes BRCA1 functions in HR repair to induce Cisplatin Chemoresistance in Lung Adenocarcinoma by Deubiquitinating FLNA.

FLNA BRCA1

5.53e-053150235541909
Pubmed

Interaction with BRCA2 suggests a role for filamin-1 (hsFLNa) in DNA damage response.

FLNA BRCA1

5.53e-053150211602572
Pubmed

Breast cancer susceptibility gene 1 (BRCAI) is a coactivator of the androgen receptor.

NCOA2 BRCA1

5.53e-053150211085509
Pubmed

Germline mutations of DICER1 in Chinese women with BRCA1/BRCA2-negative familial breast cancer.

DICER1 BRCA1

5.53e-053150225526195
Pubmed

MicroRNAs tune cerebral cortical neurogenesis.

DICER1 FOXG1

5.53e-053150222858543
Pubmed

MicroRNA-deficient NK cells exhibit decreased survival but enhanced function.

RAG1 DICER1

5.53e-053150222379033
Pubmed

Requirement of FAT and DCHS protocadherins during hypothalamic-pituitary development.

DCHS2 FAT4 FAT2

6.12e-0518150333108146
Pubmed

CHD3 and CHD4 form distinct NuRD complexes with different yet overlapping functionality.

DSG1 U2SURP TFIP11 NOL9 SF3B3 MDN1 PRRC2C NOC4L ZFR ASCC3 ZNF512

6.79e-056051501128977666
Pubmed

The in vivo Interaction Landscape of Histones H3.1 and H3.3.

SOX9 GPATCH8 BCOR TBL1XR1 BRCA1 ATAD2B TAF4 ZBTB11 ZNF512 DNMT1 ILKAP

7.10e-056081501136089195
Pubmed

USP7 targets XIAP for cancer progression: Establishment of a p53-independent therapeutic avenue for glioma.

FLNA SYNE1 TEX15 BCOR FAT2 SF3B3 MDN1

7.43e-05234150736243803
Pubmed

A Degradation Motif in STAU1 Defines a Novel Family of Proteins Involved in Inflammation.

FLNA DSG1 LSG1 DHX57 DICER1 SF3B3 BRCA1 PRRC2C FER ZFR ASCC3 ZNF512

7.64e-057241501236232890
Pubmed

FOXK2 Elicits Massive Transcription Repression and Suppresses the Hypoxic Response and Breast Cancer Carcinogenesis.

SETD1B TBL1XR1 TBL1X

8.49e-0520150327773593
Pubmed

Prediction of the coding sequences of unidentified human genes. VII. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro.

U2SURP MDN1 ALMS1 RALGPS1 KAT6B

9.10e-0510415059205841
Pubmed

MYC multimers shield stalled replication forks from RNA polymerase.

FLNA DSG1 LSG1 U2SURP TFIP11 NOL9 GPATCH8 SF3B3 MDN1 NOC4L ZFR ISG20L2 ZBTB11 DNMT1

1.03e-049891501436424410
Pubmed

Disruption of BMP4 signaling is associated with laryngeal birth defects in a mouse model.

SOX9 FOXG1

1.10e-044150237230380
Pubmed

Characterization, quantification, and assessment of immune protection potential of secretory immunoglobulin A in colostrum samples from Saudi women.

IGHA1 IGHA2

1.10e-044150224145934
Pubmed

The genes for the human VPS10 domain-containing receptors are large and contain many small exons.

SORCS1 SORT1

1.10e-044150211499680
Pubmed

UHRF1 is associated with epigenetic silencing of BRCA1 in sporadic breast cancer.

BRCA1 DNMT1

1.10e-044150219943104
Pubmed

Mutation of l7Rn3 shows that Odz4 is required for mouse gastrulation.

TENM4 DLG2

1.10e-044150215489520
Pubmed

SRC2 controls CD4+ T cell activation via stimulating c-Myc-mediated upregulation of amino acid transporter Slc7a5.

NCOA2 RAG1

1.10e-044150237094160
Pubmed

Defective immunoglobulin A (IgA) glycosylation and IgA deposits in patients with IgA nephropathy.

IGHA1 IGHA2

1.10e-044150223398317
Pubmed

Steroid nuclear receptor coactivator 2 controls immune tolerance by promoting induced Treg differentiation via up-regulating Nr4a2.

NCOA2 RAG1

1.10e-044150235704583
Pubmed

GWAS of five gynecologic diseases and cross-trait analysis in Japanese.

SOX9 BRCA1

1.10e-044150231488892
Pubmed

The P2Y2 receptor mediates uptake of matrix-retained and aggregated low density lipoprotein in primary vascular smooth muscle cells.

FLNA LRP1

1.10e-044150227522265
Pubmed

SOXE group transcription factors regulates the expression of FoxG1 during inner ear development.

SOX9 FOXG1

1.10e-044150235878429
Pubmed

Correlations of SOX9 expression with serum IGF1 and inflammatory cytokines IL-1α and IL-6 in skin lesions of patients with acne.

SOX9 IL1A

1.10e-044150229771405
Pubmed

METTL3 and N6-Methyladenosine Promote Homologous Recombination-Mediated Repair of DSBs by Modulating DNA-RNA Hybrid Accumulation.

METTL3 BRCA1

1.10e-044150232615088
Pubmed

TBL1-TBLR1 and beta-catenin recruit each other to Wnt target-gene promoter for transcription activation and oncogenesis.

TBL1XR1 TBL1X

1.10e-044150218193033
Pubmed

TBL1 and TBLR1 phosphorylation on regulated gene promoters overcomes dual CtBP and NCoR/SMRT transcriptional repression checkpoints.

TBL1XR1 TBL1X

1.10e-044150218374649
Pubmed

Characterization of sorCS1, an alternatively spliced receptor with completely different cytoplasmic domains that mediate different trafficking in cells.

SORCS1 SORT1

1.10e-044150212482870
Pubmed

miR-185 suppresses tumor proliferation by directly targeting E2F6 and DNMT1 and indirectly upregulating BRCA1 in triple-negative breast cancer.

BRCA1 DNMT1

1.10e-044150225319390
Pubmed

VprBP (DCAF1) Regulates RAG1 Expression Independently of Dicer by Mediating RAG1 Degradation.

RAG1 DICER1

1.10e-044150229925675
Pubmed

Identification of Filamin A as a BRCA1-interacting protein required for efficient DNA repair.

FLNA BRCA1

1.10e-044150220305393
Pubmed

The pro-neurotrophin receptor sortilin is a major neuronal apolipoprotein E receptor for catabolism of amyloid-β peptide in the brain.

SORT1 LRP1

1.10e-044150223283348
Pubmed

DNA methyltransferase 1/3a overexpression in sporadic breast cancer is associated with reduced expression of estrogen receptor-alpha/breast cancer susceptibility gene 1 and poor prognosis.

BRCA1 DNMT1

1.10e-044150224464625
Pubmed

Knockdown of Foxg1 in Sox9+ supporting cells increases the trans-differentiation of supporting cells into hair cells in the neonatal mouse utricle.

SOX9 FOXG1

1.10e-044150233099273
Pubmed

Human Antiviral Protein IFIX Suppresses Viral Gene Expression during Herpes Simplex Virus 1 (HSV-1) Infection and Is Counteracted by Virus-induced Proteasomal Degradation.

LSG1 U2SURP TFIP11 NOL9 DICER1 MDN1 PRPF38A

1.15e-04251150728077445
Pubmed

Acetylation-Mimic Mutation of TRIM28-Lys304 to Gln Attenuates the Interaction with KRAB-Zinc-Finger Proteins and Affects Gene Expression in Leukemic K562 Cells.

ZNF229 ZNF84 ZNF841 ZBTB11 ZNF160 ZNF512

1.41e-04181150637372979
Pubmed

Analysis of the Histone H3.1 Interactome: A Suitable Chaperone for the Right Event.

FLNA MAT2A U2SURP SF3B3 TAF4 DNMT1

1.45e-04182150626527279
Pubmed

Arginine methylation and ubiquitylation crosstalk controls DNA end-resection and homologous recombination repair.

FLNA DSG1 U2SURP MDH1 SF3B3 PRRC2C ZFR TAF4 WDR1 ALG13

1.48e-045511501034728620
Pubmed

Quantitative study of the interactome of PKCζ involved in the EGF-induced tumor cell chemotaxis.

FLNA TEX15 DICER1 PTPN14 OSBPL1A AKAP11

1.54e-04184150623402259
Pubmed

Proximity-dependent Mapping of the Androgen Receptor Identifies Kruppel-like Factor 4 as a Functional Partner.

NCOA2 U2SURP BCOR TBL1XR1 TNRC18 ATXN1 TBL1X

1.72e-04268150733640491
Pubmed

Association of the 3' UTR transcription factor LBP-1c/CP2/LSF polymorphism with late-onset Alzheimer's disease.

LRP1 C1R

1.83e-045150212555245
InteractionSDCBP2 interactions

ADAP1 NFASC ZNF581 ATXN1 PRPF38A THAP6

1.32e-05721456int:SDCBP2
InteractionGUSBP5 interactions

OFD1 BCOR TBL1XR1 TNRC18 ALMS1 TBL1X

1.67e-05751456int:GUSBP5
InteractionHDAC4 interactions

CABLES2 SETD1B LSG1 MPDZ DHX57 TFIP11 BCOR TBL1XR1 FRY PTPN14 TENM4 ATXN1 PRRC2C FER ZFR DNMT1 TBL1X

2.61e-0574414517int:HDAC4
InteractionGBA1LP interactions

BCOR TBL1XR1 SORT1 TBL1X

2.89e-05251454int:GBA1LP
InteractionGSK3A interactions

OFD1 LSG1 U2SURP MPDZ BCAR1 DICER1 TBC1D8 TNRC18 SF3B3 MDN1 ALMS1 AKAP11 ASCC3

3.17e-0546414513int:GSK3A
GeneFamilyCadherin related

DCHS2 FAT4 FAT2

1.09e-0417101324
GeneFamilyZinc fingers CCCH-type|Zinc fingers matrin-type

ZMAT4 ZMAT1

3.06e-045101284
GeneFamilyZinc fingers C2H2-type|ZF class homeoboxes and pseudogenes

ZNF581 ZNF229 ZNF19 ZNF605 ZNF37A ZNF84 ZNF841 ZNF606 ZBTB11 ZNF160 ZNF844 ZNF512

6.58e-047181011228
GeneFamilyX-linked mental retardation|RNA helicases

DICER1 ASCC3

1.64e-031110121168
GeneFamilyFibronectin type III domain containing

NFASC PTPRQ FNDC9 ROBO2 ASTN1

2.04e-031601015555
GeneFamilyArmadillo repeat containing|Protein phosphatase 1 regulatory subunits

BRCA1 FER DLG2 AKAP11 HYDIN

3.47e-031811015694
GeneFamilyZinc fingers C2HC-type|PHD finger proteins|Lysine acetyltransferases

NANOS2 KAT6B

3.52e-0316101266
GeneFamilyZinc fingers ZZ-type|Lysine acetyltransferases

NCOA2 KAT6B

3.98e-03171012486
CoexpressionDACOSTA_UV_RESPONSE_VIA_ERCC3_DN

NCOA2 SOX9 U2SURP SPG11 GPATCH8 DICER1 FAM171A1 MDN1 BRCA1 ATXN1 PRRC2C ATAD2B AKAP11 TAF4 ASCC3 KAT6B ZBTB11 TBL1X

1.56e-0685614718M4500
CoexpressionLAKE_ADULT_KIDNEY_C5_PROXIMAL_TUBULE_EPITHELIAL_CELLS_STRESS_INFLAM

PCSK5 POR BCOR SORCS1 TENM4 MDN1 PRRC2C OSBPL1A DLG2 ROBO2 KAT6B ZMAT1

4.36e-0641714712M39224
CoexpressionGSE13306_RA_VS_UNTREATED_TCONV_UP

LSG1 NOL9 PTPN14 ALMS1 RALGPS1 ISG20L2 ZNF512 TBL1X

1.80e-052001478M3234
CoexpressionGSE21380_TFH_VS_GERMINAL_CENTER_TFH_CD4_TCELL_UP

PIK3AP1 MPDZ ECE1 TBC1D8 TENM4 LRP1 C1R IL1A

1.80e-052001478M7506
CoexpressionBUSSLINGER_GASTRIC_IMMUNE_CELLS

KIF21B FLNA KLHL28 OFD1 VPS13C SYNE1 U2SURP SPG11 GPATCH8 RSRC2 TBL1XR1 DICER1 SF3B3 ATXN1 TPP1 ZFR AKAP11 WDR1 ASCC3 KAT6B DNMT1 PSD4

3.07e-05149214722M40023
CoexpressionNAKAYA_PBMC_FLUARIX_FLUVIRIN_AGE_18_50YO_3DY_DN

SETD1B OFD1 LSG1 U2SURP HBP1 RSRC2 MDH1 MDN1 KAT6B ZBTB11 ILKAP

3.41e-0543214711M41149
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ Genital tubercle M_emap-6706_top-relative-expression-ranked_1000

NPR3 KLHL28 DSG1 ADAM23 U2SURP PCDHB12 PCDHB11 CILK1 ZMAT4 TBL1XR1 SORCS1 OSBPL1A ASTN1 ZFR LTBP1 ZNF841 ZNF606 KAT6B

1.64e-0583614518gudmap_developingLowerUrinaryTract_e14.5_ Genital tubercle M_1000
CoexpressionAtlasFacebaseRNAseq_e10.5_Neural Epithelium Overlying Lateral Eminence_top-relative-expression-ranked_2500_k-means-cluster#5

NCOA2 FAT4 ADAM23 VPS13C POR RSRC2 ALMS1 BRCA1 ATXN1 SETBP1 ASTN1 ACSBG2 KAT6B CD200 DOP1A

4.28e-0565414515Facebase_RNAseq_e10.5_Neural Epithelium Overlying Lateral Eminence_2500_K5
CoexpressionAtlaskidney_P3_CapMes_Crym_top-relative-expression-ranked_1000

B3GLCT ADAM23 MAT2A MROH2A PCDHB11 ZNF229 TBL1XR1 SORT1 PTPN14 TENM4 ALMS1 BRCA1 SETBP1 ROBO2 LTBP1 DISP1

5.49e-0574914516gudmap_kidney_P3_CapMes_Crym_1000
ToppCellCOVID-19-lung-Artery_EC|lung / Disease (COVID-19 only), tissue and cell type

FAT4 NPR3 ECE1 FAM171A1 TMTC1 PTPN14 SETBP1 LTBP1

2.54e-071881508eecd7482b3c97d7f49993cb17edfab30c61232fc
ToppCellLPS-IL1RA-Hematopoietic_Meg-Ery-Mes-Epi-like|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SOX9 LSG1 ZMAT4 BCOR OSBPL1A HSDL1 ZMAT1

1.07e-061571507bd45590da540a557dc8096980a45220fccb99505
ToppCellLPS-IL1RA-Hematopoietic_Meg-Ery-Mes-Epi-like-Erythroid|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SOX9 LSG1 ZMAT4 BCOR OSBPL1A HSDL1 ZMAT1

1.07e-06157150700c9a58b033b8b95b0d838f233dd077b62d8b02a
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_2|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PIK3AP1 NPR3 PTPN14 DLG2 HYDIN CD200 TBL1X

2.75e-0618115076956ecd6264f7469a25e555673bce4eb97d28f7a
ToppCellSmart-seq2-blood_(Smart-seq2)-myeloid-myeloid_monocytic-classical_monocyte|blood_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

VPS13C MUC16 TENM4 PRRC2C LRP1 ASTN1 TBL1X

3.29e-06186150723b8d51d20b05795a73892d3e20e0f9b6a207820
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

FLNA NFASC SORT1 TMTC1 FRY ASTN1 LTBP1

4.06e-061921507bfab13793e54de2550ee171397f7ece0625cdb4a
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

FLNA NFASC SORT1 TMTC1 FRY ASTN1 LTBP1

4.06e-061921507b54b0d5b88139905521c8d5d58332e89c08d589c
ToppCellkidney_cells-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

DCHS2 NPR3 SYNE1 NFASC PTPRQ C1R CD200

4.65e-061961507545d2e4469924d333e3f655f559c899fa1260196
ToppCellControl-Myeloid-TRAM1|Control / Condition, Lineage and Cell class

FLNA POR CXCL16 MDH1 SORT1 LRP1 CD151

5.14e-0619915078785ea74b006df8d115885eaad429289c41e8d5b
ToppCellTracheal-NucSeq-Stromal|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

FAT4 SYNE1 TMTC1 LRP1 C1R DLG2 LTBP1

5.31e-062001507c318d14bd6fd6f42c597eb55ac9e2f48008aeb9b
ToppCellPosterior_cortex-Neuronal-Excitatory-eN1(Slc17a7)-eN1_1-Bcl6|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

PCSK5 DCHS2 NPR3 CFAP65 SORT1 HYDIN

9.48e-06144150608005be9e3367f78ef27e125d9cce5ca53f4bd2d
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-3m-Epithelial-neuronal_stem_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

B3GLCT LSG1 DHX57 BRCA1 ISG20L2 ALG13

2.05e-0516515061703d3eb644b3c743ad3c5532b1d29ea010c79c8
ToppCellASK440-Immune-B_cell|Immune / Donor, Lineage and Cell class of Lung cells from Dropseq

ECE1 CFAP65 IGHA1 IGHA2 NLGN2 CD200

2.27e-051681506127559d1a083c68cda9fce143afcc3eec168df17
ToppCellEndothelial-A-IPF_03|World / lung cells shred on cell class, cell subclass, sample id

FAT4 NPR3 ADAM23 FAM171A1 TMTC1 CD200

2.59e-051721506a3201773a25832e92dd113fad165f1ecd37f5e91
ToppCellfacs-Marrow-KLS-18m-Lymphocytic-early_pro_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PCSK5 RAG1 HNF1A MROH2A BCAR1 DLG2

2.95e-0517615067292e014b8f697f0c2e9f47c48333de95cb44a69
ToppCellfacs-Marrow-KLS-18m-Lymphocytic-early_pro-B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PCSK5 RAG1 HNF1A MROH2A BCAR1 DLG2

2.95e-05176150688ca2f83d8301633232735f39b0683efe49d0b86
ToppCelldroplet-Liver-hepatocytes-3m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FAT4 ADAM23 PCDHB11 FAM171A1 OIT3 ALMS1

3.05e-0517715068ef41ee5d63737b810ad7371b0437625e7e1badf
ToppCelldroplet-Liver-hepatocytes-3m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FAT4 ADAM23 PCDHB11 FAM171A1 OIT3 ALMS1

3.45e-0518115064df7972f88117108698efd06b124b232f8588981
ToppCelldroplet-Liver-hepatocytes-3m-Endothelial|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FAT4 ADAM23 PCDHB11 FAM171A1 OIT3 ALMS1

3.45e-051811506cbb530566893281289026bfd93adf721decd4ca3
ToppCellControl-Stromal_mesenchymal-Lung_smooth_muscle-MatrixFB_->_Myofibroblast|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PCSK5 SORCS1 TENM4 LRP1 ROBO2 LTBP1

3.67e-0518315067eae9b3b4d1c9b135fa7cff348393d4adec474b4
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FAT4 MROH2A SORCS1 TENM4 PTPRQ HYDIN

3.79e-0518415062cbed6462fea2622871bb7e49b0df3d984239281
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FAT4 MROH2A SORCS1 TENM4 PTPRQ HYDIN

3.79e-051841506ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FAT4 MROH2A SORCS1 TENM4 PTPRQ HYDIN

3.79e-0518415062b19a8c5f823e00812908b23e66bb4e563278aff
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Renal_corpuscle_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

NFASC SORT1 FRY PTPN14 PTPRQ DLG2

3.79e-0518415067294b379ce4cb8fa75e432559082f93cd106aaf5
ToppCelldroplet-Heart-nan-18m-Endothelial|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NPR3 ECE1 TBC1D8 FRY PTPN14 CD200

3.90e-051851506a32d5cb596ebac80eb1ac301055e65d420879ec8
ToppCellAnterior_Cingulate_gyrus_(CgG)|World / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

PCSK5 DCHS2 DNAH14 ROBO2 CD151 PSD4

4.02e-05186150632af3f211f9ad5d5c6b86b83325cfbf2f8466b56
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SYNE1 DNAH14 PTPN14 HYDIN CD200 TBL1X

4.27e-05188150663a4b25a0a6e05f80f1a6dd91b817f3cf49e6b68
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

FLNA NFASC TMTC1 FRY ASTN1 LTBP1

4.40e-0518915067fbe855bfdb47d35e040b04a80fe4b729a3764e8
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell-|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

FLNA NFASC TMTC1 FRY ASTN1 LTBP1

4.40e-05189150606b35abecd29f902cf251fcc1f6ad33db7ab08a2
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

PIK3AP1 DNAH14 PTPN14 HYDIN CD200 TBL1X

4.40e-051891506904b8337e2cabac2f0bf5dad5598fc429581ed81
ToppCellrenal_medulla_nuclei|World / Celltypes from Cells and Nuclei per compartment and clinical group

NCOA2 SYNE1 FAM171A1 FRY PTPN14 SETBP1

4.40e-051891506830d9cd0dd706bce22eb2416f07b2c31c870a05a
ToppCellCOVID-19-lung-Vein_EC|COVID-19 / Disease (COVID-19 only), tissue and cell type

FAT4 NPR3 ADAM23 ECE1 FAM171A1 TMTC1

4.53e-0519015061caeaef78326734c1e31a0c4739190d5c5a77b9e
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Degenerative_Podocyte|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

NPR3 NFASC FRY PTPRQ C1R CD151

4.53e-05190150692710caaff05123cf8e909319d7ac441d9b31a66
ToppCellChildren_(3_yrs)-Endothelial-endothelial_cell_of_artery|Children_(3_yrs) / Lineage, Cell type, age group and donor

FAT4 NPR3 FAM171A1 TMTC1 PTPN14 SETBP1

4.53e-051901506f6c38d197fd9d69a4f97cb2e72cd4747984c1a86
ToppCellEndothelial-A-Myositis-ILD_01|World / lung cells shred on cell class, cell subclass, sample id

FAT4 ADAM23 ECE1 FAM171A1 TMTC1 LTBP1

4.66e-051911506f702dfe88a9b04091dae87df61b2b4f43525f86a
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

DCHS2 NFASC TMTC1 LRP1 C1R LTBP1

4.66e-051911506a58c75e9580139fb370b498d95660f10f3a2a27b
ToppCell5'-GW_trimst-2-SmallIntestine-Mesenchymal-mesothelial_cell|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CPA4 MUC16 PTPRQ CD151 DISP1 CD200

4.66e-0519115065343a527de6b0f852f45020a91f5b4869e78f13a
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

FAT4 NFASC DNAI3 SETBP1 LRP1 LTBP1

4.66e-051911506c54c420a94dc749ebc67fc64c5614663f4b9798d
ToppCell5'-GW_trimst-2-SmallIntestine-Mesenchymal-mesothelial_cell-Mesothelium|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CPA4 MUC16 PTPRQ CD151 DISP1 CD200

4.66e-051911506a25a5f9a380031fdaf57677a079f97a90f0550c0
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

FAT4 NFASC DNAI3 SETBP1 LRP1 LTBP1

4.66e-051911506cb0aee740b08f7d5fdd2717ecf7429043b277ae7
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Myocytic_interstitial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

FLNA NFASC ECE1 TMTC1 SETBP1 LTBP1

4.66e-05191150604c4d454b57e29a8d1dcdeb4678ce71bdc29b77b
ToppCellfacs-Heart-LA-3m-Endothelial-endothelial_cell_of_endocardium|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NPR3 ECE1 TBC1D8 TMTC1 FRY PTPN14

4.80e-05192150614a816ef116aa992f86edab411f043cf7d07fe04
ToppCellFetal_29-31_weeks-Mesenchymal-myofibroblast_cell-D150|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

FAT4 TENM4 ROBO2 LTBP1 DISP1 CD200

4.80e-05192150672881b280a415e65f87a80ca1369cbb0b722a0c4
ToppCellPCW_07-8.5-Epithelial-Epithelial_neuroendo-epi_NE_progenitor_(7)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

ZMAT4 TBC1D8 FRY RALGPS1 TMPRSS3 ZMAT1

4.80e-051921506b99f8236ef4ccdc75c02abea381cae6453205f6f
ToppCellfacs-Heart-LA-3m-Endothelial-endocardial_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NPR3 ECE1 TBC1D8 TMTC1 FRY PTPN14

4.80e-051921506847822514d747a21d5eb40e04ba9a023fd32bd65
ToppCellwk_20-22-Mesenchymal-Myofibro_&_SMC-Myofibro_2|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

PCSK5 FLNA ROBO2 LTBP1 DISP1 CD200

4.94e-0519315062f203f6f0c2135acb046c9351a633c3b5b254a46
ToppCellCOVID-19-Fibroblasts-Other_FB|COVID-19 / group, cell type (main and fine annotations)

FAT4 TENM4 SETBP1 DLG2 ROBO2 LTBP1

4.94e-051931506e6b75be08e33c1de079fb5c02f0b4468128b369c
ToppCellfacs-Liver-Non-hepatocytes-24m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FAT4 ADAM23 ECE1 FAM171A1 OIT3 IL1A

5.08e-051941506c8b9551b93a5aed62154b487db90130604a6125c
ToppCell10x_3'_v2v3-Non-neoplastic-Glial-Neuronal-Oligodendrocyte-Oligodendrocyte-E|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

ADAP1 CILK1 SORT1 FAM171A1 OSBPL1A DLG2

5.08e-051941506cb0422e7607dbd77204428b7e2c70dfe14a6ca11
ToppCellkidney_cells-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

NPR3 NFASC FRY PTPRQ C1R CD151

5.08e-05194150643eb677a76634bb9a48a40e0d607c4936ae64bcc
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Renal_corpuscle_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

NPR3 SYNE1 NFASC PTPRQ C1R CD200

5.08e-0519415061374600957c7d7f0b05fd2c1186f521b9096d4ef
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

FLNA NFASC TMTC1 LRP1 C1R LTBP1

5.23e-051951506edd4cd8402af81737b2074f9dce71cc6ab09be7e
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

NFASC TMTC1 SETBP1 LRP1 C1R LTBP1

5.23e-0519515063c3703f092b6fc1b7333426fb5e2823bfb74bb57
ToppCellBronchial-NucSeq-Stromal-Fibroblastic-Fibro_myofibroblast|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

FAT4 ZNF605 TENM4 ROBO2 LTBP1 ZNF844

5.23e-051951506f5e91ce20a7ce528dc4c1a968c7bf096bf45c528
ToppCell5'-Parenchyma_lung-Endothelial-Blood_vessel_EC-pulmonary_artery_endothelial_cell-EC_arterial-EC_arterial_L.2.4.1.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

PCSK5 NPR3 ECE1 TMTC1 PTPN14 LTBP1

5.38e-051961506cf7f384c1771274e766bab03ecc3dfbd13f2df60
ToppCellfacs-Limb_Muscle-ForelimbandHindlimb-3m-Mesenchymal-skeletal_muscle_satellite_cell|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HBP1 TENM4 PRRC2C LTBP1 ZSWIM4 CD200

5.53e-0519715065bc11aff92da2a0aca8473f997fe7a99f3cae75d
ToppCellTracheal-NucSeq-Stromal-Fibroblastic-Fibro_myofibroblast|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

PCSK5 FAT4 SYNE1 LRP1 C1R LTBP1

5.53e-0519715060dd71e399f253787fa546a7e90c5373180b89ffd
ToppCellBAL-Severe-Myeloid-TRAM-TRAM2|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)

POR CXCL16 MDH1 SORT1 LRP1 CD151

5.53e-051971506d8ef5cb88dd66e112cb94217b9ad5cd70164f1d0
ToppCellCOVID-19-Fibroblasts-Intermediate_pathological_FB|COVID-19 / group, cell type (main and fine annotations)

TENM4 SETBP1 C1R DLG2 ROBO2 LTBP1

5.53e-051971506f1c8936986123a3151140c374fcd62d6705c530b
ToppCell3'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SYNE1 MPDZ DNAI3 CFAP65 CPLANE1 HYDIN

5.53e-05197150674a2c6cb8fcfe53dd9a2b36492a16c58f38e51c9
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

NFASC TMTC1 SETBP1 LRP1 C1R LTBP1

5.53e-051971506ae0435f4b4a9cdedb1c201fc56921048390097bf
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

NFASC TMTC1 SETBP1 LRP1 C1R LTBP1

5.53e-05197150637f6b6f2809b952382eaebb642b0aad6371f4251
ToppCellBAL-Severe-Myeloid-TRAM-TRAM2|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

POR CXCL16 MDH1 SORT1 LRP1 CD151

5.53e-05197150633f2fe101ae5744eea3915add37e60aa398bb97f
ToppCellBAL-Severe-Myeloid-TRAM-TRAM2-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

POR CXCL16 MDH1 SORT1 LRP1 CD151

5.53e-0519715065e9a3932ae5147a3d73dc70f1545926a692930ed
ToppCellParenchymal-NucSeq-Stromal-Fibroblastic-Fibro_peribronchial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

DCHS2 FAT4 TENM4 SETBP1 ROBO2 LTBP1

5.53e-05197150644673c38384453207871d3fd8e8ba9093cc06bc5
ToppCellSevere_COVID-19-Myeloid-TRAM2|Severe_COVID-19 / Disease group,lineage and cell class (2021.01.30)

POR CXCL16 MDH1 SORT1 LRP1 CD151

5.53e-0519715068a126cfe1529f3d75a806aa492743314a8a43ef9
ToppCellBAL-Severe-Myeloid-TRAM-TRAM2-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

POR CXCL16 MDH1 SORT1 LRP1 CD151

5.53e-0519715069262785807faeb32417fad7ef202405053e453e2
ToppCellIPF-Stromal-Myofibroblast|Stromal / Disease state, Lineage and Cell class

FAT4 DNAH14 TENM4 DLG2 ROBO2 LTBP1

5.53e-051971506f304d42fc4936fe20996e07c8dccc698a6e5e5ef
ToppCellTCGA-Skin-Metastatic-Melanoma|TCGA-Skin / Sample_Type by Project: Shred V9

PIK3AP1 KIF21B VPS13C ALMS1 ZFR KAT6B

5.69e-051981506af4fb9eb2295c7b90624b38ba25619aa15254efa
ToppCellBiopsy_Other_PF-Mesenchymal-Mesothelial_cells|Biopsy_Other_PF / Sample group, Lineage and Cell type

CPA4 MUC16 PTPRQ C1R ASTN1 CD200

5.69e-05198150686736f01e61bf4961f060b24ee1f1f48340737dd
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ADAM23 SYNE1 ZMAT4 FRY TENM4 SETBP1

5.69e-0519815068ab40fae14fe02e39bc8c8da187a5cd60c787643
ToppCellTCGA-Skin-Metastatic|TCGA-Skin / Sample_Type by Project: Shred V9

PIK3AP1 KIF21B VPS13C ALMS1 ZFR KAT6B

5.69e-051981506ad39cce004867f083f8da1954e0cf5a263815184
ToppCellTCGA-Skin-Metastatic-Melanoma-Skin_Cutaneous_Melanoma|TCGA-Skin / Sample_Type by Project: Shred V9

PIK3AP1 KIF21B VPS13C ALMS1 ZFR KAT6B

5.69e-05198150662cbf4b29e8af4983fb47a17f96da62682a5137e
ToppCelldistal-1-mesenchymal-Mesothelial|1 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

CPA4 MUC16 PTPRQ C1R ASTN1 CD200

5.85e-0519915068dd5b411d2f1626830b77a1616cc3fb67dc59338
ToppCellkidney_cells-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

DCHS2 NPR3 SYNE1 C1R CD151 CD200

5.85e-051991506b9338b739162cd8e5661c9a4dcb41a31219b5723
ToppCellControl-Myeloid-TRAM1|Myeloid / Condition, Lineage and Cell class

POR CXCL16 MDH1 SORT1 LRP1 CD151

5.85e-051991506664f5cab3fe5ab599d1944deed04857ae14a06d5
ToppCellLPS_anti-TNF-Mesenchymal_myocytic-Myofibroblastic-MatrixFB_->_Myofibroblast|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

PCSK5 FLNA FAT4 SORCS1 LRP1 ROBO2

5.85e-05199150638cfd367ee8c074c11ba54edeb7a001e375e2687
ToppCellkidney_cells-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

FLNA VPS13C GPATCH8 PRRC2C C1R CD151

5.85e-051991506174f6013af6eafa577f84205a62927f2b367fda3
ToppCellkidney_cells-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell-Parietal_Epithelial_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

DCHS2 NPR3 SYNE1 C1R CD151 CD200

5.85e-051991506c972d3036151403f26fa9d6271520639c281ab84
ToppCelldistal-2-Endothelial-Artery|2 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

PCSK5 NPR3 ECE1 TMTC1 PTPN14 LTBP1

5.85e-051991506fa8aaf7a90699e41a7a4cee5614f8c9248110327
ToppCellBrain_organoid-organoid_Paulsen_bioRxiv-1_mon-Proliferating-Cycling_Progenitors|1_mon / Sample Type, Dataset, Time_group, and Cell type.

SOX9 FAT4 MAT2A MPDZ TPP1 LTBP1

5.85e-051991506358c4b3037f59378db8916a2fbe9ed4830cf1449
ToppCellBronchial-NucSeq-Stromal-Fibroblastic-Fibro_perichondrial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

FAT4 TMTC1 TENM4 LRP1 C1R LTBP1

5.85e-051991506abd6117f8a3d7e798d8471c16d97b34aaf50fc9c
ToppCellParenchymal-10x5prime-Endothelial-Endothelia_vascular-VE_pulmonary_arterial|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

FAT4 NPR3 ECE1 FAM171A1 TMTC1 LTBP1

6.02e-052001506ac6b8bc9998d303f788511b8f111e682ea9f3df8
ToppCellParenchyma_COVID-19-Endothelial-TX-Artery|Parenchyma_COVID-19 / Sample group, Lineage and Cell type

PCSK5 NPR3 ECE1 TMTC1 PTPN14 LTBP1

6.02e-05200150634b279804475ea58fbb052b96f44128c082627a9
ToppCell10x5'-Lung-Myeloid_Mac-Alveolar_macrophages|Lung / Manually curated celltypes from each tissue

POR CXCL16 MDH1 SORT1 LRP1 CD151

6.02e-0520015063b236900df407bf5a8c44e76d003a7a37d251db6
ToppCellLung_Parenchyma-Severe-Endothelial-Endothelial-Artery|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)

PCSK5 NPR3 ECE1 TMTC1 PTPN14 LTBP1

6.02e-0520015068552cc7a439449b30b59760c3e8667217b9852b5
ToppCellTracheal-NucSeq-Stromal-Fibroblastic-Fibro_perichondrial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

FAT4 SYNE1 NFASC TMTC1 LRP1 C1R

6.02e-052001506a4ec0e80f5422b91b85264a9bb74568dd577e285
ToppCellControl_saline-Mesenchymal_myocytic-Myofibroblastic|Control_saline / Treatment groups by lineage, cell group, cell type

PCSK5 FLNA SYNE1 LRP1 ROBO2 LTBP1

6.02e-0520015069d5b3c2dcfa55d50acc2ce2c319d51aa525d4cd1
ToppCellControl_saline-Mesenchymal_myocytic-Myofibroblastic-MatrixFB_->_Myofibroblast|Control_saline / Treatment groups by lineage, cell group, cell type

PCSK5 FAT4 SORCS1 LRP1 ROBO2 LTBP1

6.02e-052001506a799fc7bb83ad0524362cb5010df949741fb7bf3
ToppCellLPS_IL1RA_TNF-Mesenchymal_myocytic-Myofibroblastic-MatrixFB_->_Myofibroblast|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

PCSK5 FLNA SORCS1 LRP1 ROBO2 LTBP1

6.02e-05200150609537dc25f8b8b4654a7c183827ee1522a41a4e0
ToppCellBronchial-NucSeq-Stromal-Fibroblastic|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

FAT4 SETBP1 LRP1 C1R ROBO2 LTBP1

6.02e-052001506cae972324d1dfea6efeaf6013f265c7c6bb48db4
ToppCellTracheal-NucSeq-Stromal-Fibroblastic-Fibro_alveolar|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

FAT4 SYNE1 LRP1 C1R ROBO2 LTBP1

6.02e-0520015063dd022e974fec7013ba18f333da63f58fbf2dd7c
ToppCellLPS_IL1RA_TNF-Mesenchymal_myocytic-Myofibroblastic-Myofibroblast|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

PCSK5 FLNA SYNE1 ROBO2 LTBP1 CPLANE1

6.02e-052001506dcdaec3ca3a3024dc1b8788c417003f84c2bffdc
ToppCellParenchymal-NucSeq-Stromal-Fibroblastic|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

NFASC SETBP1 LRP1 C1R ROBO2 LTBP1

6.02e-052001506311fab076f2ceb258e3970eb21e39344b894042a
ToppCellmLN-Dendritic_cell-Lymphoid_DC|Dendritic_cell / Region, Cell class and subclass

SETD1B CXCL16 TBC1D8 ATXN1 CD200 TBL1X

6.02e-0520015063813fa1ee1462ba83fd8b6253070f46f0b063084
ToppCellLung_Parenchyma-Severe-Endothelial-Endothelial-Artery-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

PCSK5 NPR3 ECE1 TMTC1 PTPN14 LTBP1

6.02e-05200150645c08f1befe78553bbadcc2fcffb6138306638f3
ToppCellTracheal-NucSeq-Stromal-Fibroblastic-Fibro_peribronchial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

FAT4 SYNE1 LRP1 C1R ROBO2 LTBP1

6.02e-05200150658b38f9a484ee94191091a0659ed62ebed2d4a14
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d03-09-Myeloid-Macrophage-macrophage,_alveolar-Macro_c1-C1QC|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)

PRLHR TEX15 SORT1 FRY TENM4

7.89e-05130150592913960e4367261ba08a405b61a421bc5e18169
ToppCellfacs-Heart-Unknown-3m-Endothelial-endothelial_cell_of_coronary_artery|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CPA4 MROH2A TEX15 SORCS1 PTPRQ

1.16e-0414115054aa4b3476dc5abefbd348353cfe711cd5fe3d52f
ToppCellfacs-Heart-Unknown-3m-Endothelial-coronary_vascular_endothelial_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CPA4 MROH2A TEX15 SORCS1 PTPRQ

1.16e-041411505e40c6f1b7fbaa46b3eaa55f1b37ef360b04370a8
DrugPrimaquine diphosphate [63-45-6]; Down 200; 8.8uM; MCF7; HT_HG-U133A

MPDZ DICER1 ALMS1 BRCA1 RALGPS1 ZFR KAT6B ZNF160 TBL1X

3.49e-0618614793279_DN
DrugPhenformin hydrochloride [834-28-6]; Down 200; 16.6uM; PC3; HT_HG-U133A

NPR3 DICER1 ALMS1 PRRC2C ZFR LTBP1 KAT6B ZNF160 TBL1X

4.33e-0619114794283_DN
DiseaseIntellectual Disability

SOX9 SYNE1 FRY BRCA1 TPP1 SETBP1 ASTN1 ASCC3 ZBTB11 FOXG1 ALG13

1.40e-0544714511C3714756
DiseaseOto-Palato-digital syndrome type 1

FLNA OFD1

2.40e-0521452C0265251
Diseasesensory system disease (implicated_via_orthology)

TBL1XR1 TBL1X

7.17e-0531452DOID:0050155 (implicated_via_orthology)
DiseaseDisorder of eye

B3GLCT OFD1 BCOR ALMS1 TPP1 CC2D2A CPLANE1

8.94e-052121457C0015397
DiseaseFamilial aplasia of the vermis

OFD1 CC2D2A CPLANE1

1.25e-04201453cv:C0431399
Diseaseprogranulin measurement

NCOA2 LSG1 GPATCH8

1.67e-04221453EFO_0004625
DiseasePolydactyly

OFD1 CILK1 ALMS1 CC2D2A CPLANE1

2.88e-041171455C0152427
Diseasecomplement C1r subcomponent measurement

IGHA1 C1R

4.96e-0471452EFO_0008090
Diseasecleft lip

CPA4 SYNE1 MUC16 FRY BRCA1 ATXN1 KAT6B

5.30e-042841457EFO_0003959
Diseasemajor depressive episode, major depressive disorder

SETD1B TENM4 TAF4

6.78e-04351453EFO_0007634, MONDO_0002009
Diseasevisceral heterotaxy (implicated_via_orthology)

PCSK5 OSBPL1A CC2D2A

7.99e-04371453DOID:0050545 (implicated_via_orthology)
DiseaseProstatic Neoplasms

NCOA2 RAG1 NPR3 BCAR1 TBL1XR1 BRCA1 TPP1 ROBO2 ZNF160 DNMT1

9.71e-0461614510C0033578
DiseaseMalignant neoplasm of prostate

NCOA2 RAG1 NPR3 BCAR1 TBL1XR1 BRCA1 TPP1 ROBO2 ZNF160 DNMT1

9.71e-0461614510C0376358
Diseaseunipolar depression, bipolar disorder

FAT4 SYNE1 TENM4 SETBP1 ASCC3

1.06e-031561455EFO_0003761, MONDO_0004985
DiseaseIschemic stroke

NCOA2 DCHS2 B3GLCT MPDZ SETBP1 OSBPL1A AGBL1

1.14e-033241457HP_0002140
DiseaseNeurodevelopmental Disorders

TBL1XR1 SETBP1 FOXG1 ALG13

1.16e-03931454C1535926
Diseasecreatinine measurement

KIF21B HNF1A POR TBC1D8 FRY PTPN14 ALMS1 PRRC2C SETBP1 TAF4 WDR1 ASCC3 PSD4

1.29e-0399514513EFO_0004518
DiseaseGastrointestinal Stromal Sarcoma

CC2D2A ZBTB11 DISP1

1.61e-03471453C3179349
DiseaseGastrointestinal Stromal Tumors

CC2D2A ZBTB11 DISP1

1.92e-03501453C0238198
DiseaseEpilepsy

FLNA ASTN1 FOXG1 ALG13

2.09e-031091454C0014544
Diseasesulfate measurement

HNF1A DNAI3

2.10e-03141452EFO_0007864
Diseasetriiodothyronine measurement

DLG2 AGBL1

2.75e-03161452EFO_0008392
Diseasemigraine without aura, susceptibility to, 4

LRP1 DLG2

2.75e-03161452MONDO_0011847
Diseasehypertension (is_implicated_in)

PRLHR NPR3 ECE1 BRCA1

3.05e-031211454DOID:10763 (is_implicated_in)
Diseasecolorectal cancer (is_implicated_in)

HNF1A BCOR DICER1 BRCA1

3.05e-031211454DOID:9256 (is_implicated_in)
Disease1-Methylhistidine measurement

NCOA2 ALMS1

3.11e-03171452EFO_0021543
Diseaseparental longevity

PIK3AP1 PCSK5 POR SORCS1 TMTC1 SETBP1 ROBO2 PSD4

3.16e-034941458EFO_0007796
Diseasebirth weight

CPA4 HNF1A PTPN14 TENM4 ATAD2B IL1A DNMT1

3.68e-033991457EFO_0004344
Diseasefish consumption measurement

TENM4 ATXN1 DLG2

3.89e-03641453EFO_0010139
Diseaseobesity (implicated_via_orthology)

DCHS2 FAT4 PRLHR ALMS1 HSDL1

4.28e-032151455DOID:9970 (implicated_via_orthology)
Diseaseunipolar depression, bipolar disorder, schizophrenia

PCSK5 DCHS2

4.30e-03201452EFO_0003761, MONDO_0004985, MONDO_0005090
Diseasevenous thromboembolism, fibrinogen measurement

DCHS2 HNF1A ZNF160

4.42e-03671453EFO_0004286, EFO_0004623
Diseasehaptoglobin measurement

ZNF19 HYDIN

4.74e-03211452EFO_0004640

Protein segments in the cluster

PeptideGeneStartEntry
TDKHETVVSYLPLSH

ACSBG2

261

Q5FVE4
TKTRAPGHYEFTQVH

C2orf16

1246

Q68DN1
SGYLHKQALVTATHP

ALG13

166

Q9NP73
ESPYHVLDTKARHQQ

ADAM23

126

O75077
ATIIHHYAFSENPTV

B3GLCT

166

Q6Y288
NTHKSTPASYHADIN

DNMT1

1026

P26358
PSAVYEHNHVSLRAA

BTBD16

431

Q32M84
NHHAVYDVPPSVSKD

BCAR1

301

P56945
SSIAPSDADIIQHYK

FAT4

4626

Q6V0I7
STSYSQHREKPSIFH

ALMS1

1141

Q8TCU4
PYHISSTACQAKAHL

AKAP11

791

Q9UKA4
YSGIVAHQKHLLPTS

CXCL16

106

Q9H2A7
SHYPTHVKVTAQDLI

DOP1A

1466

Q5JWR5
HPHGLQVTYLKDNST

ADAP1

191

O75689
IVTYRSNTHPALHSF

CENPVL1

186

A0A0U1RR11
YALSPHTVIQTTHSA

ATXN1

426

P54253
YCKHSTIVPENAAHQ

DICER1

1121

Q9UPY3
HLKEYQSFTDLHSPT

DNAI3

321

Q8IWG1
SVANKHGHYPNTIAE

PIK3AP1

366

Q6ZUJ8
EFHKHYARISTSPSV

BCOR

356

Q6W2J9
AHTLYPKEHEAQSNA

C1R

501

P00736
GQSKTHTINAYHLDP

DISP1

1166

Q96F81
KSASAEAANEIHYIP

ASTN1

191

O14525
KTQYANHHHIPAAAS

AGBL1

376

Q96MI9
HKDSEYSHLTRVAPA

NPR3

166

P17342
TNYFHKTLAHVPEII

RAG1

936

P15918
AKTESVQYDHPNHTV

NOL12

91

Q9UGY1
SCSYDHLTTLPHVQK

RALGPS1

246

Q5JS13
HVDAAAAAVPLSYQH

OFD1

851

O75665
TLIDHSLPYSHSAAV

KAT6B

1826

Q8WYB5
TYKDTAHTEAVHPST

MUC16

7756

Q8WXI7
SQTFATCHSKVYHLP

MUC6

1066

Q6W4X9
HSDVAPTHILYAVNA

NOL9

561

Q5SY16
ETHGTKNYFTSVAHP

IL1A

226

P01583
LIVTASKHAYVPNSA

FAM171A1

86

Q5VUB5
PEKLHHDSRTYLVNS

KATNBL1

111

Q9H079
APHHTYSKIDHIVGS

nan

196

O00370
HHYVTSIAKAPAVQD

MDN1

3331

Q9NU22
ATPGHTKHFQTLYVE

LSG1

416

Q9H089
LFHYSRTQEATHPVK

NMS

71

Q5H8A3
YSIASSSKVHPNSVH

POR

456

P16435
AQHLATDVGYKTAEH

NRAP

886

Q86VF7
SELISESKYRQHPHS

NRAP

1196

Q86VF7
YSFHHEEKVPRTISS

FNDC9

46

Q8TBE3
SHASDVVLYHQHKQP

LRP1

4131

Q07954
HPLSISIFHYGTSQK

MAT2A

326

P31153
QSSSAAIHKPYLHFT

ATAD2B

741

Q9ULI0
KPEQKYVHFTSTTHQ

CFAP65

1291

Q6ZU64
NHSSTQYPDVNHAKV

MDH1

186

P40925
HRLHQKSPSQYSEEE

GPATCH8

826

Q9UKJ3
EIPYATHHLTAAALA

FOXG1

371

P55316
KSVSFNPQHVHIYSA

PCSK5

256

Q92824
SVRVHVTEQSHYAPS

FAT2

3516

Q9NYQ8
LPVQKTQTIHSTYSH

LTBP1

526

Q14766
YTSRDHLAKHFQVPV

OIT3

466

Q8WWZ8
EQTPFRHLYTSKTHL

CYLC1

96

P35663
SQHDLVVTGSKDHYV

KIF21B

1466

O75037
LQYFHPKSLTRDTSH

ISG20L2

271

Q9H9L3
ALYSHKPEVAQYTHT

HNF1A

501

P20823
HHASLVMSQDPYKVT

GNA15

111

P30679
HTYLIHKASSLSDPV

OSBPL1A

586

Q9BXW6
YTTSDTLKPSVHVHD

DSG1

841

Q02413
ESRHVYSSHQLKTPD

NANOS2

71

P60321
HPTLVTYADHSKLSA

METTL3

141

Q86U44
AVKSYTINPNSHFHV

PCDHB12

166

Q9Y5F1
LHSLATFIYNSHPDK

PTPRQ

526

Q9UMZ3
VQPIVSLHYKFSEDH

CD200

141

P41217
SSLSYHTHVKESTPL

DCHS2

2666

Q6V1P9
AVKSYTISPNSHFHI

PCDHB11

166

Q9Y5F2
EAHLAKVHGQPASYA

OVOL3

166

O00110
HDHSKYPGSVNSAVL

NFASC

676

O94856
RHPEKYQGSSVSNLH

BRCA1

256

P38398
IINTSHFPVSFHADK

HYDIN

1616

Q4G0P3
IHAHKVVLASVSPYF

KLHL28

46

Q9NXS3
KYVHSSQHVIRSGDP

CC2D2A

386

Q9P2K1
IVTYRSNTHPALHSF

CENPVL2

186

P0DPI3
QSDHLAVPSSAELHY

CPLANE1

2621

Q9H799
FSNIPQLIDHHYTTK

FER

521

P16591
IDHHDNTYTVKYTPV

FLNA

926

P21333
TKNDGYVHIHPSSVN

DHX57

1256

Q6P158
VYHGPHANSEVEVKS

CPA4

276

Q9UI42
IVTYRSNTHPALHSF

CENPVL3

186

A0A0U1RRI6
HAALSLSKEHNPTQY

ILKAP

251

Q9H0C8
KSVTCHVKHYTNPSQ

IGHA1

81

P01876
SKLYQPHTFTDSHVS

CEP162

1156

Q5TB80
NPYDLQVVSAHTAKH

DNAH14

316

Q0VDD8
PVHIIATSKSLHSYA

HBP1

136

O60381
HGYVLQSHISPLKAS

DLG2

56

Q15700
HVKHYTNSSQDVTVP

IGHA2

86

P01877
YHKVTAAELQTLAPA

ECE1

331

P42892
AVLVNSHYDVKSPSH

FRY

826

Q5TBA9
SPKVYAHHAVSTLGI

HSDL1

271

Q3SXM5
HISQDPLHYSIASVS

DGLUCY

276

Q7Z3D6
YKNSLNVVHHPSFLS

CENPI

676

Q92674
TKRYHQPGHEAVTSA

CD151

131

P48509
LQRHYHPEVSKAASV

NOC4L

441

Q9BVI4
VAPAVATAKLHADYQ

NLGN2

461

Q8NFZ4
LYPTNALVTHKSDSH

CABLES2

246

Q9BTV7
SPITAKIIHHYVSSC

MROH2A

801

A6NES4
ITELHPDVVSYVSHA

TAF4

891

O00268
QSEVSVSPRASKHHY

RSRC2

26

Q7L4I2
HIHASYSISQKLNVP

SORT1

461

Q99523
LSAVLALPAAVHTYH

PRLHR

186

P49683
LLSHIHASSYISPEK

PRAME

266

P78395
AQFLKHYPDIHNAST

SYNE1

276

Q8NF91
VHAHLQGTKDSYSAI

SYNE1

4006

Q8NF91
GVHHSLATPATHYTK

PSD4

841

Q8NDX1
ATSTPDLASHRHKYV

PTPN14

576

Q15678
AYSVEHNQLEAHPKA

PRRC2C

846

Q9Y520
EHHYVHNSPAVTAVA

SETD1B

326

Q9UPS6
VLHAYLQTLSSPASH

DIP2C-AS1

206

Q8N8Z3
EHAHQVVVAKYAPSG

WDR1

56

O75083
HIKTEQLSPSHYSEQ

SOX9

396

P48436
KTVPATNYNHHLVGA

THAP6

111

Q8TBB0
YKSTVNIPLSHGVVH

OR5T2

6

Q8NGG2
HTLTKHQEPVYSVAF

TBL1XR1

436

Q9BZK7
TQSSKSEEHHLYSNP

U2SURP

806

O15042
IRNHHVASLSFYTPE

ASCC3

2136

Q8N3C0
YKAEVSRTDHPSHLQ

CILK1

351

Q9UPZ9
NKSVYSILHVGDHTE

NCOA2

156

Q15596
TLTQHQRTHTGEKPY

ZNF37A

341

P17032
IHSQLHNYHPAEVKS

SPG11

1376

Q96JI7
VCTHTLTKHQEPVYS

TBL1X

496

O60907
LPDDKVTALHHSVYV

TMPRSS3

176

P57727
DKLLYAGHVQTVHSP

TNRC18

2171

O15417
HASPQHTQTEKDYPL

UHRF1BP1L

421

A0JNW5
SHVKSHSVTEPYRCN

ZBTB11

811

O95625
SLAIHQTIHTGEKPY

ZNF160

411

Q9HCG1
VAHYQQAIKLSPSHH

TMTC1

636

Q8IUR5
LSQHQRIHTGEKPYS

ZNF19

316

P17023
TSATSNIEYAHVPHL

MPDZ

66

O75970
LKQVHANHPVHYDTS

TBC1D8

391

O95759
DLTNPTKVTHLYNHS

TENM4

2316

Q6N022
ESTHNLTLPKQYVAH

VPS13C

516

Q709C8
VKDAHSIHGTNPQYL

PRPF38A

6

Q8NAV1
PYATTQILHSNSIHE

ROBO2

996

Q9HCK4
SAVATLPKQVADHYD

MARS2

451

Q96GW9
SPLEAHKANTLVYHV

SF3B3

156

Q15393
LSSHQKTHTGERPYQ

ZNF229

476

Q9UJW7
HIRADTAHKPSEYQE

ZNF844

121

Q08AG5
SLTNHQRIHTGEKPY

ZNF84

501

P51523
SLATHQTVHTGDKPY

ZNF841

271

Q6ZN19
VASYTVHQAPVAAHT

ZFR

61

Q96KR1
VHQAPVAAHTVTAAY

ZFR

66

Q96KR1
YLQRHSITHSEVKPF

ZNF581

101

Q9P0T4
SLSQKHPQHSVEYEG

TEX15

336

Q9BXT5
HLHLKVSENPYTSGI

SORCS1

526

Q8WY21
QKHSTLHYDTGLPQD

SETBP1

186

Q9Y6X0
SESGVKYHINSVHAE

ZNF512

451

Q96ME7
HQITHTIEKPYSCSE

ZNF605

271

Q86T29
SAVVADSHYQGKIHA

ZMAT4

86

Q9H898
SYSQISHKHNVPDDG

TFIP11

281

Q9UBB9
VSQIEHFYKPDTHAQ

ZNF606

231

Q8WXB4
SSPLIAQSHYVGKVH

ZMAT1

131

Q5H9K5
YLISAHHTEVLPTAQ

ZSWIM4

206

Q9H7M6
LSNESALPHVHTVSY

TPP1

311

O14773