Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	extracellular matrix structural constituent	LAMA3 FBN1 VWF SSPOP LTBP4	2.39e-05	188	37	5	GO:0005201
GeneOntologyCellularComponent	microfibril	FBN1 LTBP4	2.22e-04	13	36	2	GO:0001527
GeneOntologyCellularComponent	collagen-containing extracellular matrix	LAMA3 FBN1 VWF SSPOP LTBP4 HPX	2.63e-04	530	36	6	GO:0062023
GeneOntologyCellularComponent	extracellular matrix	LAMA3 FBN1 VWF SSPOP LTBP4 HPX	8.14e-04	656	36	6	GO:0031012
GeneOntologyCellularComponent	external encapsulating structure	LAMA3 FBN1 VWF SSPOP LTBP4 HPX	8.27e-04	658	36	6	GO:0030312
Domain	Growth_fac_rcpt_	LAMA3 ATRN SCUBE1 FBN1 LTBP4 NOTCH1 INSRR STAB1	4.91e-10	156	36	8	IPR009030
Domain	EGF_1	LAMA3 ATRN SCUBE1 FBN1 SSPOP LTBP4 NOTCH1 STAB1	2.35e-08	255	36	8	PS00022
Domain	EGF_2	LAMA3 ATRN SCUBE1 FBN1 SSPOP LTBP4 NOTCH1 STAB1	3.17e-08	265	36	8	PS01186
Domain	EGF_3	ATRN SCUBE1 FBN1 SSPOP LTBP4 NOTCH1 STAB1	2.79e-07	235	36	7	PS50026
Domain	EGF	LAMA3 ATRN SCUBE1 FBN1 LTBP4 NOTCH1 STAB1	2.79e-07	235	36	7	SM00181
Domain	EGF-like_dom	LAMA3 ATRN SCUBE1 FBN1 LTBP4 NOTCH1 STAB1	4.13e-07	249	36	7	IPR000742
Domain	EGF-like_CS	LAMA3 ATRN SCUBE1 FBN1 LTBP4 NOTCH1 STAB1	5.67e-07	261	36	7	IPR013032
Domain	EGF_CA	SCUBE1 FBN1 LTBP4 NOTCH1 STAB1	3.51e-06	122	36	5	SM00179
Domain	EGF-like_Ca-bd_dom	SCUBE1 FBN1 LTBP4 NOTCH1 STAB1	3.80e-06	124	36	5	IPR001881
Domain	EGF_CA	SCUBE1 FBN1 LTBP4 NOTCH1	2.21e-05	86	36	4	PF07645
Domain	EGF_LAM_2	LAMA3 ATRN STAB1	2.58e-05	30	36	3	PS50027
Domain	EGF_LAM_1	LAMA3 ATRN STAB1	2.58e-05	30	36	3	PS01248
Domain	EGF_Ca-bd_CS	SCUBE1 FBN1 LTBP4 NOTCH1	3.54e-05	97	36	4	IPR018097
Domain	EGF_CA	SCUBE1 FBN1 LTBP4 NOTCH1	3.84e-05	99	36	4	PS01187
Domain	ASX_HYDROXYL	SCUBE1 FBN1 LTBP4 NOTCH1	4.00e-05	100	36	4	PS00010
Domain	Laminin_EGF	LAMA3 ATRN STAB1	4.13e-05	35	36	3	PF00053
Domain	EGF_Lam	LAMA3 ATRN STAB1	4.13e-05	35	36	3	SM00180
Domain	EGF-type_Asp/Asn_hydroxyl_site	SCUBE1 FBN1 LTBP4 NOTCH1	5.02e-05	106	36	4	IPR000152
Domain	Laminin_EGF	LAMA3 ATRN STAB1	5.30e-05	38	36	3	IPR002049
Domain	ARM	ODAD2 INSC KPNA3	6.19e-05	40	36	3	SM00185
Domain	TB	FBN1 LTBP4	7.54e-05	7	36	2	PF00683
Domain	-	FBN1 LTBP4	1.00e-04	8	36	2	3.90.290.10
Domain	Armadillo	ODAD2 INSC KPNA3	1.01e-04	47	36	3	IPR000225
Domain	TB	FBN1 LTBP4	1.29e-04	9	36	2	PS51364
Domain	TB_dom	FBN1 LTBP4	1.29e-04	9	36	2	IPR017878
Domain	EGF_extracell	ATRN NOTCH1 STAB1	2.09e-04	60	36	3	IPR013111
Domain	EGF_2	ATRN NOTCH1 STAB1	2.09e-04	60	36	3	PF07974
Domain	EGF_3	SCUBE1 STAB1	2.36e-04	12	36	2	PF12947
Domain	TIL	VWF SSPOP	2.36e-04	12	36	2	PF01826
Domain	EGF_dom	SCUBE1 STAB1	2.36e-04	12	36	2	IPR024731
Domain	C8	VWF SSPOP	2.36e-04	12	36	2	PF08742
Domain	Unchr_dom_Cys-rich	VWF SSPOP	2.78e-04	13	36	2	IPR014853
Domain	C8	VWF SSPOP	2.78e-04	13	36	2	SM00832
Domain	TIL_dom	VWF SSPOP	3.24e-04	14	36	2	IPR002919
Domain	VWD	VWF SSPOP	4.26e-04	16	36	2	SM00216
Domain	VWF_type-D	VWF SSPOP	4.26e-04	16	36	2	IPR001846
Domain	VWFD	VWF SSPOP	4.26e-04	16	36	2	PS51233
Domain	VWD	VWF SSPOP	4.26e-04	16	36	2	PF00094
Domain	CTCK_1	VWF SSPOP	5.42e-04	18	36	2	PS01185
Domain	VWC_out	VWF SSPOP	6.05e-04	19	36	2	SM00215
Domain	Cys_knot_C	VWF SSPOP	1.05e-03	25	36	2	IPR006207
Domain	CTCK_2	VWF SSPOP	1.05e-03	25	36	2	PS01225
Domain	cEGF	SCUBE1 FBN1	1.14e-03	26	36	2	IPR026823
Domain	cEGF	SCUBE1 FBN1	1.14e-03	26	36	2	PF12662
Domain	Arm	ODAD2 KPNA3	1.62e-03	31	36	2	PF00514
Domain	EGF	ATRN NOTCH1 STAB1	1.82e-03	126	36	3	PF00008
Domain	VWFC_1	VWF SSPOP	2.18e-03	36	36	2	PS01208
Domain	VWC	VWF SSPOP	2.43e-03	38	36	2	SM00214
Domain	VWFC_2	VWF SSPOP	2.43e-03	38	36	2	PS50184
Domain	ARM_REPEAT	ODAD2 KPNA3	2.69e-03	40	36	2	PS50176
Domain	VWF_dom	VWF SSPOP	2.96e-03	42	36	2	IPR001007
Domain	CUB	ATRN SCUBE1	4.01e-03	49	36	2	PF00431
Domain	CUB	ATRN SCUBE1	4.18e-03	50	36	2	SM00042
Domain	-	ATRN SCUBE1	4.51e-03	52	36	2	2.60.120.290
Domain	CUB	ATRN SCUBE1	4.68e-03	53	36	2	PS01180
Domain	CUB_dom	ATRN SCUBE1	5.39e-03	57	36	2	IPR000859
Pathway	KEGG_MEDICUS_REFERENCE_PLASMIN_MEDIATED_ACTIVATION_OF_LATENT_TGF_BETA	FBN1 LTBP4	1.22e-04	8	30	2	M47850
Pathway	WP_GENE_REGULATORY_NETWORK_MODELLING_SOMITOGENESIS	NOTCH1 WNT3A	1.95e-04	10	30	2	MM15839
Pathway	WP_GENE_REGULATORY_NETWORK_MODELING_SOMITOGENESIS	NOTCH1 WNT3A	2.38e-04	11	30	2	M39647
Pathway	REACTOME_EXTRACELLULAR_MATRIX_ORGANIZATION	LAMA3 SCUBE1 FBN1 VWF LTBP4	3.89e-04	300	30	5	M610
Pathway	REACTOME_DISEASES_ASSOCIATED_WITH_O_GLYCOSYLATION_OF_PROTEINS	SSPOP NOTCH1 LARGE1	3.97e-04	68	30	3	M27303
Pathway	REACTOME_SIGNALING_BY_TGF_BETA_RECEPTOR_COMPLEX	FBN1 SKIL LTBP4	5.72e-04	77	30	3	MM14670
Pathway	PID_BETA_CATENIN_DEG_PATHWAY	SSPOP WNT3A	6.56e-04	18	30	2	M31
Pubmed	Overexpression of CDC14B causes mitotic arrest and inhibits zygotic genome activation in mouse preimplantation embryos.	CDC14C CDC14B	1.10e-06	2	37	2	19923902
Pubmed	The Cdc14B phosphatase displays oncogenic activity mediated by the Ras-Mek signaling pathway.	CDC14C CDC14B	1.10e-06	2	37	2	21502810
Pubmed	Wnt and Notch pathways have interrelated opposing roles on prostate progenitor cell proliferation and differentiation.	NOTCH1 WNT3A	1.10e-06	2	37	2	21308863
Pubmed	Birth and rapid subcellular adaptation of a hominoid-specific CDC14 protein.	CDC14C CDC14B	1.10e-06	2	37	2	18547142
Pubmed	Quantitative proteomic profiling of the extracellular matrix of pancreatic islets during the angiogenic switch and insulinoma progression.	LAMA3 FBN1 VWF SSPOP LTBP4	1.17e-06	175	37	5	28071719
Pubmed	Early-onset aging and defective DNA damage response in Cdc14b-deficient mice.	CDC14C CDC14B	3.30e-06	3	37	2	21262768
Pubmed	Cdc14b regulates mammalian RNA polymerase II and represses cell cycle transcription.	CDC14C CDC14B	3.30e-06	3	37	2	22355704
Pubmed	CDC14B acts through FZR1 (CDH1) to prevent meiotic maturation of mouse oocytes.	CDC14C CDC14B	3.30e-06	3	37	2	19129509
Pubmed	Cdc14A and Cdc14B Redundantly Regulate DNA Double-Strand Break Repair.	CDC14C CDC14B	3.30e-06	3	37	2	26283732
Pubmed	Novel roles for Notch, Wnt and Hedgehog in hematopoesis derived from human pluripotent stem cells.	NOTCH1 WNT3A	3.30e-06	3	37	2	20336604
Pubmed	TBX1 is required for normal stria vascularis and semicircular canal development.	ATRN FBN1 STAB1	4.88e-06	31	37	3	31550482
Pubmed	GSK3β negatively regulates oligodendrocyte differentiation and myelination in vivo.	NOTCH1 WNT3A	6.60e-06	4	37	2	21319221
Pubmed	Latent transforming growth factor beta-binding protein 1 interacts with fibrillin and is a microfibril-associated protein.	FBN1 LTBP4	6.60e-06	4	37	2	12429738
Pubmed	CDC14A phosphatase is essential for hearing and male fertility in mouse and human.	CDC14C CDC14B	6.60e-06	4	37	2	29293958
Pubmed	Mis12 controls cyclin B1 stabilization via Cdc14B-mediated APC/CCdh1 regulation during meiotic G2/M transition in mouse oocytes.	CDC14C CDC14B	6.60e-06	4	37	2	32341029
Pubmed	Comparison of an expanded ataxia interactome with patient medical records reveals a relationship between macular degeneration and ataxia.	FBN1 VWF LTBP4 NOTCH1	7.63e-06	118	37	4	21078624
Pubmed	A role for Wnt signalling in self-renewal of haematopoietic stem cells.	NOTCH1 WNT3A	1.10e-05	5	37	2	12717450
Pubmed	Rescue of a Wnt mutation by an activated form of LEF-1: regulation of maintenance but not initiation of Brachyury expression.	NOTCH1 WNT3A	1.10e-05	5	37	2	11447280
Pubmed	Characterization of the Extracellular Matrix of Normal and Diseased Tissues Using Proteomics.	FBN1 VWF LTBP4 HPX	1.30e-05	135	37	4	28675934
Pubmed	Latent transforming growth factor beta-binding proteins and fibulins compete for fibrillin-1 and exhibit exquisite specificities in binding sites.	FBN1 LTBP4	1.65e-05	6	37	2	19349279
Pubmed	Screening for N-glycosylated proteins by liquid chromatography mass spectrometry.	ATRN VWF HPX	1.74e-05	47	37	3	14760718
Pubmed	Extracellular matrix remodelling in response to venous hypertension: proteomics of human varicose veins.	LAMA3 FBN1 VWF LTBP4	1.77e-05	146	37	4	27068509
Pubmed	Notch1 haploinsufficiency causes ascending aortic aneurysms in mice.	FBN1 NOTCH1	2.30e-05	7	37	2	29093270
Pubmed	Protein interactome reveals converging molecular pathways among autism disorders.	FBN1 VWF MPND LTBP4 NOTCH1 STAB1	2.58e-05	560	37	6	21653829
Pubmed	The matrisome: in silico definition and in vivo characterization by proteomics of normal and tumor extracellular matrices.	LAMA3 FBN1 VWF LTBP4	2.99e-05	167	37	4	22159717
Pubmed	Wnt3a plays a major role in the segmentation clock controlling somitogenesis.	NOTCH1 WNT3A	3.07e-05	8	37	2	12636920
Pubmed	Endothelial expression of the Notch ligand Jagged1 is required for vascular smooth muscle development.	VWF NOTCH1	3.07e-05	8	37	2	18245384
Pubmed	Microfibril-associated glycoprotein-2 interacts with fibrillin-1 and fibrillin-2 suggesting a role for MAGP-2 in elastic fiber assembly.	FBN1 VWF	3.95e-05	9	37	2	12122015
Pubmed	Oscillations of the snail genes in the presomitic mesoderm coordinate segmental patterning and morphogenesis in vertebrate somitogenesis.	NOTCH1 WNT3A	4.93e-05	10	37	2	16516838
Pubmed	Suppression of Notch signalling by the COUP-TFII transcription factor regulates vein identity.	VWF NOTCH1	6.02e-05	11	37	2	15875024
Pubmed	YAP regulates the expression of Hoxa1 and Hoxc13 in mouse and human oral and skin epithelial tissues.	NOTCH1 WNT3A	7.22e-05	12	37	2	25691658
Pubmed	The role of presenilin 1 during somite segmentation.	NOTCH1 WNT3A	8.53e-05	13	37	2	11262239
Pubmed	Inhibition of notch1-dependent cardiomyogenesis leads to a dilated myopathy in the neonatal heart.	VWF NOTCH1	8.53e-05	13	37	2	20558824
Pubmed	A mechanism for gene-environment interaction in the etiology of congenital scoliosis.	NOTCH1 WNT3A	9.94e-05	14	37	2	22484060
Pubmed	Molecular regionalization of the neocortex is disrupted in Fgf8 hypomorphic mutants.	NR2F1 WNT3A	9.94e-05	14	37	2	12642494
Pubmed	Platelet storage pool deficiency associated with inherited abnormalities of the inner ear in the mouse pigment mutants muted and mocha.	ATRN FBN1	9.94e-05	14	37	2	1912584
Pubmed	Wnt3a-/--like phenotype and limb deficiency in Lef1(-/-)Tcf1(-/-) mice.	NOTCH1 WNT3A	9.94e-05	14	37	2	10090727
Pubmed	LEF1-mediated regulation of Delta-like1 links Wnt and Notch signaling in somitogenesis.	NOTCH1 WNT3A	9.94e-05	14	37	2	15545629
Pubmed	Dynamic CREB family activity drives segmentation and posterior polarity specification in mammalian somitogenesis.	NOTCH1 WNT3A	1.15e-04	15	37	2	23671110
Pubmed	Role for Lhx2 in corticogenesis through regulation of progenitor differentiation.	NOTCH1 WNT3A	1.15e-04	15	37	2	23454273
Pubmed	Role of LTBP4 in alveolarization, angiogenesis, and fibrosis in lungs.	VWF LTBP4	1.15e-04	15	37	2	28684544
Pubmed	Mesodermal defects and cranial neural crest apoptosis in alpha5 integrin-null embryos.	NOTCH1 WNT3A	1.15e-04	15	37	2	9334279
Pubmed	Notch pathway targets proangiogenic regulator Sox17 to restrict angiogenesis.	VWF NOTCH1	1.15e-04	15	37	2	24755984
Pubmed	COUP-TFI controls Notch regulation of hair cell and support cell differentiation.	NR2F1 NOTCH1	1.15e-04	15	37	2	16914494
Pubmed	A primary expression map of the chromosome 15q15 region containing the recessive form of limb-girdle muscular dystrophy (LGMD2A) gene.	UBR1 FBN1	1.31e-04	16	37	2	7633422
Pubmed	Fbxw7α- and GSK3-mediated degradation of p100 is a pro-survival mechanism in multiple myeloma.	FBXW4 NOTCH1	1.31e-04	16	37	2	22388891
Pubmed	Zic2 and Zic3 synergistically control neurulation and segmentation of paraxial mesoderm in mouse embryo.	NOTCH1 WNT3A	1.67e-04	18	37	2	17490632
Pubmed	Signaling by FGF4 and FGF8 is required for axial elongation of the mouse embryo.	NOTCH1 WNT3A	1.86e-04	19	37	2	22954964
Pubmed	Fbw7 controls neural stem cell differentiation and progenitor apoptosis via Notch and c-Jun.	FBXW4 NOTCH1	1.86e-04	19	37	2	20935640
Pubmed	Migration Speed of Cajal-Retzius Cells Modulated by Vesicular Trafficking Controls the Size of Higher-Order Cortical Areas.	NR2F1 WNT3A	1.86e-04	19	37	2	26387718
Pubmed	α5β1 integrin-mediated adhesion to fibronectin is required for axis elongation and somitogenesis in mice.	NOTCH1 WNT3A	1.86e-04	19	37	2	21799763
Pubmed	Prediction of the coding sequences of unidentified human genes. IX. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro.	ATRN SSPOP LARGE1	1.93e-04	105	37	3	9628581
Pubmed	The Wnt3a/β-catenin target gene Mesogenin1 controls the segmentation clock by activating a Notch signalling program.	NOTCH1 WNT3A	2.07e-04	20	37	2	21750544
Pubmed	Increased expression of Wnt2 and SFRP4 in Tsk mouse skin: role of Wnt signaling in altered dermal fibrillin deposition and systemic sclerosis.	FBN1 WNT3A	2.28e-04	21	37	2	17943183
Pubmed	NotI flanking sequences: a tool for gene discovery and verification of the human genome.	LAMA3 ZBTB46	2.28e-04	21	37	2	12136098
Pubmed	FGF signaling expands embryonic cortical surface area by regulating Notch-dependent neurogenesis.	NR2F1 NOTCH1	2.51e-04	22	37	2	22031906
Pubmed	Netrin 1 directs vascular patterning and maturity in the developing kidney.	LTBP4 NOTCH1	2.75e-04	23	37	2	37818607
Pubmed	Prox1 is required for granule cell maturation and intermediate progenitor maintenance during brain neurogenesis.	NOTCH1 WNT3A	2.99e-04	24	37	2	20808958
Pubmed	Sfrp1 Modulates Cell-signaling Events Underlying Telencephalic Patterning, Growth and Differentiation.	NOTCH1 WNT3A	2.99e-04	24	37	2	30084950
Pubmed	Foxg1 confines Cajal-Retzius neuronogenesis and hippocampal morphogenesis to the dorsomedial pallium.	NR2F1 WNT3A	2.99e-04	24	37	2	15858069
Pubmed	The Transcription Factor Foxg1 Promotes Optic Fissure Closure in the Mouse by Suppressing Wnt8b in the Nasal Optic Stalk.	NR2F1 WNT3A	2.99e-04	24	37	2	28729440
Pubmed	Sall4 regulates posterior trunk mesoderm development by promoting mesodermal gene expression and repressing neural genes in the mesoderm.	NOTCH1 WNT3A	3.25e-04	25	37	2	38345319
Pubmed	Single Cell and Open Chromatin Analysis Reveals Molecular Origin of Epidermal Cells of the Skin.	NOTCH1 WNT3A	3.25e-04	25	37	2	30220568
Pubmed	Dissecting Wnt/beta-catenin signaling during gastrulation using RNA interference in mouse embryos.	NOTCH1 WNT3A	3.25e-04	25	37	2	15857914
Pubmed	Type 1 fibroblast growth factor receptor in cranial neural crest cell-derived mesenchyme is required for palatogenesis.	NOTCH1 WNT3A	3.52e-04	26	37	2	23754280
Pubmed	Adamts18 modulates the development of the aortic arch and common carotid artery.	LAMA3 FBN1	3.52e-04	26	37	2	34189436
Pubmed	Modulation of the notch signaling by Mash1 and Dlx1/2 regulates sequential specification and differentiation of progenitor cell types in the subcortical telencephalon.	NR2F1 NOTCH1	3.52e-04	26	37	2	12397111
Pubmed	Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.	FBXW4 ATRN FBN1 VWF SKIL STAB1 KPNA3	3.60e-04	1285	37	7	35914814
Pubmed	Genetic loci influencing natural variations in femoral bone morphometry in mice.	FBXW4 FBN1	3.80e-04	27	37	2	11518254
Pubmed	Non-canonical Wnt Signaling through Ryk Regulates the Generation of Somatostatin- and Parvalbumin-Expressing Cortical Interneurons.	NR2F1 WNT3A	3.80e-04	27	37	2	31257105
Pubmed	Lateral Thalamic Eminence: A Novel Origin for mGluR1/Lot Cells.	NR2F1 WNT3A	4.09e-04	28	37	2	27178193
Pubmed	A novel role for Dbx1-derived Cajal-Retzius cells in early regionalization of the cerebral cortical neuroepithelium.	NR2F1 WNT3A	4.09e-04	28	37	2	20668538
Pubmed	SMRT-mediated repression of an H3K27 demethylase in progression from neural stem cell to neuron.	NR2F1 NOTCH1	4.39e-04	29	37	2	17928865
Pubmed	A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration.	ELP5 SSPOP LTBP4 NOTCH1 KPNA3	4.41e-04	608	37	5	16713569
Pubmed	iRhom2 mutation leads to aberrant hair follicle differentiation in mice.	KRT85 NOTCH1	4.70e-04	30	37	2	25546423
Pubmed	p63 regulates multiple signalling pathways required for ectodermal organogenesis and differentiation.	NOTCH1 WNT3A	4.70e-04	30	37	2	16524929
Pubmed	Heritable Thoracic Aortic Disease Overview	FBN1 NOTCH1	4.70e-04	30	37	2	20301299
Pubmed	L-type voltage-dependent calcium channel alpha subunit 1C is a novel candidate gene associated with secondary hyperparathyroidism: an application of haplotype-based analysis for multiple linked single nucleotide polymorphisms.	VWF STC2 LTBP4	4.77e-04	143	37	3	20424473
Pubmed	NFIA controls telencephalic progenitor cell differentiation through repression of the Notch effector Hes1.	NOTCH1 WNT3A	5.35e-04	32	37	2	20610746
Pubmed	Ndrg2 regulates vertebral specification in differentiating somites.	NOTCH1 WNT3A	5.35e-04	32	37	2	22819676
Pubmed	NOTCH maintains developmental cardiac gene network through WNT5A.	NOTCH1 WNT3A	5.35e-04	32	37	2	30347193
Pubmed	Extracellular matrix signatures of human primary metastatic colon cancers and their metastases to liver.	FBN1 VWF LTBP4	5.81e-04	153	37	3	25037231
Pubmed	Fgf15-mediated control of neurogenic and proneural gene expression regulates dorsal midbrain neurogenesis.	VWF WNT3A	6.05e-04	34	37	2	21172336
Pubmed	Wnt5a and Wnt11 regulate mammalian anterior-posterior axis elongation.	NOTCH1 WNT3A	6.41e-04	35	37	2	25813538
Pubmed	Loss of Usp9x disrupts cell adhesion, and components of the Wnt and Notch signaling pathways in neural progenitors.	NOTCH1 WNT3A	6.41e-04	35	37	2	28808228
Pubmed	Six3 inactivation causes progressive caudalization and aberrant patterning of the mammalian diencephalon.	SSPOP WNT3A	6.78e-04	36	37	2	18094027
Pubmed	Human colostrum: identification of minor proteins in the aqueous phase by proteomics.	ATRN STC2 HPX	6.86e-04	162	37	3	16502470
Pubmed	MTG8 interacts with LHX6 to specify cortical interneuron subtype identity.	NR2F1 NOTCH1	7.96e-04	39	37	2	36064547
Pubmed	New candidate genes identified for controlling mouse gonadal sex determination and the early stages of granulosa and Sertoli cell differentiation.	VWF SLITRK1	8.37e-04	40	37	2	19864314
Pubmed	Pbx Regulates Patterning of the Cerebral Cortex in Progenitors and Postmitotic Neurons.	NR2F1 WNT3A	8.37e-04	40	37	2	26671461
Pubmed	Identification and characterization of proteins interacting with SIRT1 and SIRT3: implications in the anti-aging and metabolic effects of sirtuins.	LAMA3 KPNA3	8.80e-04	41	37	2	19343720
Pubmed	Hepatitis C virus infection protein network.	VWF LTBP4	9.23e-04	42	37	2	18985028
Pubmed	Six3 and Six6 Are Jointly Required for the Maintenance of Multipotent Retinal Progenitors through Both Positive and Negative Regulation.	NOTCH1 WNT3A	9.23e-04	42	37	2	30485816
Pubmed	A genome-wide search for quantitative trait loci affecting the cortical surface area and thickness of Heschl's gyrus.	ACAA2 SLITRK1	9.67e-04	43	37	2	25130324
Interaction	NTN5 interactions	FBN1 LTBP4 NOTCH1	1.12e-05	24	37	3	int:NTN5
Interaction	ST14 interactions	LAMA3 ATRN FBN1 STC2 WNT3A	3.63e-05	207	37	5	int:ST14
GeneFamily	Armadillo repeat containing\|Protein phosphatase 1 regulatory subunits	ODAD2 KPNA3	1.60e-03	43	25	2	409
Coexpression	NABA_ECM_GLYCOPROTEINS	LAMA3 FBN1 VWF SSPOP LTBP4	7.03e-06	191	37	5	MM17059
Coexpression	NABA_ECM_GLYCOPROTEINS	LAMA3 FBN1 VWF SSPOP LTBP4	7.97e-06	196	37	5	M3008
Coexpression	HATADA_METHYLATED_IN_LUNG_CANCER_DN	LAMA3 SCUBE1 SOHLH2	1.79e-05	36	37	3	M11680
Coexpression	NABA_CORE_MATRISOME	LAMA3 FBN1 VWF SSPOP LTBP4	3.72e-05	270	37	5	MM17057
Coexpression	NABA_CORE_MATRISOME	LAMA3 FBN1 VWF SSPOP LTBP4	4.06e-05	275	37	5	M5884
Coexpression	BENPORATH_SOX2_TARGETS	UBR1 MPND SKIL CDC14B NOTCH1 KPNA3 LARGE1	6.50e-05	734	37	7	M3835
Coexpression	NABA_MATRISOME	LAMA3 SCUBE1 FBN1 VWF SSPOP LTBP4 WNT3A HPX	6.65e-05	1008	37	8	MM17056
Coexpression	NABA_MATRISOME	LAMA3 SCUBE1 FBN1 VWF SSPOP LTBP4 WNT3A HPX	7.53e-05	1026	37	8	M5889
Coexpression	GSE23505_IL6_IL1_IL23_VS_IL6_IL1_TGFB_TREATED_CD4_TCELL_DN	ACAA2 MPND CDC14B KPNA3	1.75e-04	199	37	4	M7865
Coexpression	GSE23321_CD8_STEM_CELL_MEMORY_VS_CENTRAL_MEMORY_CD8_TCELL_UP	ARHGAP36 INSRR HPX LARGE1	1.78e-04	200	37	4	M8436
Coexpression	GSE43955_TGFB_IL6_VS_TGFB_IL6_IL23_TH17_ACT_CD4_TCELL_60H_UP	ACAA2 VWF STAB1 KPNA3	1.78e-04	200	37	4	M9671
Coexpression	GSE5589_IL6_KO_VS_IL10_KO_LPS_AND_IL10_STIM_MACROPHAGE_180MIN_UP	FBXW4 LAMA3 SKIL KPNA3	1.78e-04	200	37	4	M6668
CoexpressionAtlas	dev gonad_e12.5_M_InterstitLeydig_MafB_top-relative-expression-ranked_500	ACAA2 SCUBE1 FBN1 STC2 LTBP4 CDC14B	2.60e-05	364	35	6	gudmap_dev gonad_e12.5_M_InterstitLeydig_MafB_500
ToppCell	droplet-Lung-21m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell-pulmonary_artery_endothelial_cell_l27\|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	LAMA3 FBN1 VWF STC2 LTBP4	4.48e-07	186	37	5	c116cc9f41971622264434ebe29d18e719b0ae19
ToppCell	Tracheal-10x5prime-Stromal-Peri/Epineurial_-NAF_endoneurial\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	ZBTB46 FBN1 LTBP4 NR2F1 HPX	6.10e-07	198	37	5	7a0c4dbc8c99968d42af00a718f4fedc544599ec
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Neural-neural_cell-Schwann_Cell_/_Neural\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	LAMA3 ABLIM3 INSC HPX	9.28e-06	160	37	4	14dfa519e68bab4bce890ddb66fa7763f18d9f19
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Neural\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	LAMA3 ABLIM3 INSC HPX	9.28e-06	160	37	4	5b7789d4668ed7732babedc32d812233b430e0bd
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Neural-neural_cell-Schwann_Cell_/_Neural-\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	LAMA3 ABLIM3 INSC HPX	9.28e-06	160	37	4	bba1486faaad5299e10f4fe17c6d149c28dc2560
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Neural-neural_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	LAMA3 ABLIM3 INSC HPX	9.28e-06	160	37	4	839bbdfd4e4c7b48260c8bfb7670378634405e1d
ToppCell	facs-Mammary_Gland-Mammary_Gland-18m-Epithelial-luminal_epithelial_cell_of_mammary_gland\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SOHLH2 VWF STC2 INSRR	1.32e-05	175	37	4	0992de1c7bffcb6890584357a7a0a8955927da6c
ToppCell	facs-Lung-18m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell-pulmonary_artery_endothelial_cell_l25\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	LAMA3 VWF LTBP4 STAB1	1.48e-05	180	37	4	67c5068b660cd5e727a665cefe3bd5f8ae887221
ToppCell	facs-Diaphragm-Limb_Muscle-24m-Endothelial\|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	VWF ABLIM3 NOTCH1 STAB1	1.48e-05	180	37	4	f9b7d5eb7b6ea72253c89bdc351ad2b4a53f7d8e
ToppCell	facs-Lung-24m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell-pulmonary_artery_endothelial_cell_l25\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	LAMA3 VWF LTBP4 STAB1	1.48e-05	180	37	4	baa5825e6ce23a98d9c21d024a4b0ab8ba353d0c
ToppCell	facs-Diaphragm-Limb_Muscle-24m-Endothelial-endothelial_cell\|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	VWF ABLIM3 NOTCH1 STAB1	1.48e-05	180	37	4	53db6032eda0e590ae7e01c9c3b472785ea6782f
ToppCell	facs-Lung-24m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	LAMA3 VWF LTBP4 STAB1	1.48e-05	180	37	4	2d608b9394d28d19cfc85c6ac94003d5177c8a92
ToppCell	facs-Diaphragm-Limb_Muscle-24m-Endothelial-nan\|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	VWF ABLIM3 NOTCH1 STAB1	1.48e-05	180	37	4	28bc10b9d0e4430b952260014d8a6ff337860ac6
ToppCell	facs-Lung-24m-Endothelial-arterial_endothelial\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	LAMA3 VWF LTBP4 STAB1	1.48e-05	180	37	4	0f9b27054358c4737eed06c8ea01987cccc3cb55
ToppCell	facs-Lung-18m-Endothelial-arterial_endothelial\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	LAMA3 VWF LTBP4 STAB1	1.54e-05	182	37	4	ebc812ed3f25839ea25f76b952c463d79a8325b1
ToppCell	droplet-Lung-21m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell\|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	LAMA3 FBN1 VWF LTBP4	1.54e-05	182	37	4	c7f2d24697affa530b748ab32b1d40bdc1bdc20a
ToppCell	droplet-Lung-21m-Endothelial-arterial_endothelial\|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	LAMA3 FBN1 VWF LTBP4	1.54e-05	182	37	4	d95635b74e8cd8bc00bfe40340806b59fb9bee43
ToppCell	facs-Lung-18m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	LAMA3 VWF LTBP4 STAB1	1.54e-05	182	37	4	47ff6b4002a4167412c79210651316d1342503f9
ToppCell	5'-Adult-LymphNode-Endothelial-blood_vessel_EC-Mature_venous_EC\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	VWF ABLIM3 STC2 STAB1	1.57e-05	183	37	4	a644258ba90acc62d571623e429d72ffc4b69203
ToppCell	facs-Brain_Myeloid-Cortex\|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	VWF LTBP4 STAB1 HPX	1.61e-05	184	37	4	17f63dd671f9ff3dd2860d8de41b05c35c095950
ToppCell	PND10-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-AEC-AEC_prolif\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	VWF LTBP4 NOTCH1 STAB1	1.64e-05	185	37	4	87151ab95530e70d61328b336518df58db584acb
ToppCell	droplet-Heart-nan-18m-Endothelial\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	VWF ABLIM3 NOTCH1 STAB1	1.64e-05	185	37	4	a32d5cb596ebac80eb1ac301055e65d420879ec8
ToppCell	droplet-Liver-Hepatocytes-18m-Endothelial-endothelial_cell_of_hepatic_sinusoid\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ZBTB46 LTBP4 NOTCH1 STAB1	1.68e-05	186	37	4	60830822d3de3147816693404fd03392e04c2b8e
ToppCell	facs-Mammary_Gland-Mammary_Gland-21m-Epithelial-luminal_epithelial_cell_of_mammary_gland\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	VWF ODAD2 STC2 KRT85	1.68e-05	186	37	4	02fbb02c495e7d64c4ab50e42e5197782f2c0816
ToppCell	droplet-Liver-Hepatocytes-18m-Endothelial\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ZBTB46 LTBP4 NOTCH1 STAB1	1.68e-05	186	37	4	37860daeecd6d412bd3797f30496a56da667fbd1
ToppCell	droplet-Liver-Hepatocytes-18m-Endothelial-endothelial_cell_of_hepatic_sinusoid\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ZBTB46 LTBP4 NOTCH1 STAB1	1.68e-05	186	37	4	baebeffdd426ce767190ddefc857cc78e6a58d36
ToppCell	PCW_13-14-Mesenchymal-Mesenchymal_fibroblastic-mes_immature_COL13A1^pos_fibro2_(5)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	RPL10A FBN1 LTBP4 NR2F1	1.71e-05	187	37	4	13731298bc562ec29582f5da1b4c97261284f6f1
ToppCell	5'-Adult-Distal_Rectal-Endothelial-lymphatic_endothelial-LEC6_(ADAMTS4+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ABLIM3 SSPOP NR2F1 NOTCH1	1.75e-05	188	37	4	524a12f433c7b6f33fad36c0716afa06cd3235e9
ToppCell	5'-Adult-Distal_Rectal-Endothelial-lymphatic_endothelial\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ABLIM3 SSPOP NR2F1 NOTCH1	1.75e-05	188	37	4	d2610b81b3c7f22977b5e2137b1f61410fc4ef16
ToppCell	facs-Trachea-18m-Endothelial-endothelial_cell_of_trachea\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	VWF ABLIM3 NOTCH1 STAB1	1.79e-05	189	37	4	e830fa0ddc3dccfaf9e88e8c416ed6aab12e3e3f
ToppCell	facs-Trachea-nan-18m-Endothelial\|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	VWF ABLIM3 NOTCH1 STAB1	1.79e-05	189	37	4	5ced78f4b5c276b1bab24df807c00cf5ac8ed3d4
ToppCell	facs-Trachea-18m-Endothelial-endothelial_cell_of_trachea-tracheal_endothelial_cell\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	VWF ABLIM3 NOTCH1 STAB1	1.79e-05	189	37	4	ecbe079606406f47d4fc97fe1670790dda8e10de
ToppCell	facs-Trachea-18m-Endothelial\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	VWF ABLIM3 NOTCH1 STAB1	1.79e-05	189	37	4	f635f3f13bced3bcf796cf55723a2df851f973fe
ToppCell	facs-Trachea-nan-18m-Endothelial-nan\|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	VWF ABLIM3 NOTCH1 STAB1	1.79e-05	189	37	4	2105d8b011b93a460237e00bc029efd7762dc8d5
ToppCell	facs-Trachea-nan-18m-Endothelial-endothelial_cell\|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	VWF ABLIM3 NOTCH1 STAB1	1.79e-05	189	37	4	100eda87ac9c38dddcfa58408b057867a1738acb
ToppCell	(4)_Endothelial_cells-(40)_EC-arterial\|(4)_Endothelial_cells / Cell class and subclass of bone marrow stroma cells in homeostatis	FBN1 VWF ABLIM3 LTBP4	1.82e-05	190	37	4	ff774faf3f12759d11e50ed7d189288bb79e22e1
ToppCell	facs-Limb_Muscle-ForelimbandHindlimb-3m-Endothelial\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	VWF ABLIM3 NOTCH1 STAB1	1.82e-05	190	37	4	bb1476b44dd49e1dd52a636a91c4600b6d4fbe2e
ToppCell	facs-Limb_Muscle-ForelimbandHindlimb-3m-Endothelial-nan\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	VWF ABLIM3 NOTCH1 STAB1	1.82e-05	190	37	4	d180205c70b5ca9bc5a01a2e6cb42fcebc7f630d
ToppCell	facs-Limb_Muscle-ForelimbandHindlimb-3m-Endothelial-endothelial_cell\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	VWF ABLIM3 NOTCH1 STAB1	1.82e-05	190	37	4	38a815abf0ac5cac6071737cadc54a514f62d37d
ToppCell	10x3'2.3-week_14-16-Endothelial-stroma-immature_EC\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	VWF NR2F1 STAB1 LARGE1	1.90e-05	192	37	4	5af3b2b38495e925497c48f605d618bbf970965d
ToppCell	LPS-IL1RA+antiTNF-Stromal_mesenchymal-Matrix_Fibroblast-MatrixFB\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	FBN1 ABLIM3 LTBP4 NR2F1	1.94e-05	193	37	4	fb28717fadd06c3840636d25409ce80c9254bd34
ToppCell	kidney_cells-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Ascending_Vasa_Recta_Endothelial_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	SCUBE1 VWF NOTCH1 STAB1	1.94e-05	193	37	4	daefbfd3a3dd1351fbe94b9abfd807db44d56c24
ToppCell	facs-Liver-Liver_non-hepato/SCs-18m-Endothelial-nan\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SCUBE1 ODAD2 LTBP4 STAB1	1.94e-05	193	37	4	2483bb7f398e4fa0ef09c8bd584ed25703853f03
ToppCell	facs-Heart-LA-3m-Endothelial\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	VWF ABLIM3 NOTCH1 STAB1	1.98e-05	194	37	4	33cc4f1d716cb71d54cdedbe9bbdc0d7b17c4777
ToppCell	COVID-19-kidney-PLVAP+EC\|kidney / Disease (COVID-19 only), tissue and cell type	SCUBE1 VWF STC2 STAB1	2.02e-05	195	37	4	a436483fec137584611f86b7a498a4dc2aa19cd3
ToppCell	10x_3'_v2v3-Non-neoplastic-Vascular-Mural_cell-SMC_COL-D\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	FBN1 ABLIM3 STC2 NR2F1	2.02e-05	195	37	4	78cfde21dde4b877fc76c8b0d5ddaabe44b912d7
ToppCell	facs-Heart-RA-18m-Endothelial\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	VWF ABLIM3 NOTCH1 STAB1	2.02e-05	195	37	4	30c75761079fa1e1a3b84d23c88a222f459d5ce5
ToppCell	PCW_07-8.5-Mesenchymal\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	RPL10A FBN1 LTBP4 NR2F1	2.06e-05	196	37	4	8e10802f52e5e1853ea4ad34bf9a32a34e6112b5
ToppCell	Tracheal-10x5prime-Stromal-Peri/Epineurial_\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	SCUBE1 FBN1 LTBP4 NR2F1	2.10e-05	197	37	4	2cb1f557ce1400398975de94638126b4522567f3
ToppCell	10x5'v1-week_12-13-Endothelial\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	VWF ABLIM3 STC2 NR2F1	2.14e-05	198	37	4	307dd09e6bc820a148f3000f18dae7aedba4be0b
ToppCell	LPS_IL1RA_TNF-Mesenchymal_fibroblastic-Fibroblasts-Diff_MatrixFB\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	FBN1 ABLIM3 LTBP4 NR2F1	2.14e-05	198	37	4	0a4b19c3d5e65ecd24fc2ce80ac5276c813282c7
ToppCell	Bronchial-NucSeq-Endothelial-Endothelia_lymphatic-Endothelia_Lymphatic\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	ZBTB46 VWF ABLIM3 NR2F1	2.14e-05	198	37	4	b3a020522e064bb61949d38e442f24026e339364
ToppCell	Bronchial-NucSeq-Endothelial-Endothelia_lymphatic\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	ZBTB46 VWF ABLIM3 NR2F1	2.14e-05	198	37	4	fc4b7c3ad52bc5c8b40fa04a156bfbb58afa2872
ToppCell	10x5'v1-week_12-13-Endothelial-stroma\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	VWF ABLIM3 STC2 NR2F1	2.14e-05	198	37	4	122215d9288533ad03562cf777e846504863df9a
ToppCell	Tracheal-NucSeq-Stromal-Peri/Epineurial_-NAF_epineurial\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	SCUBE1 FBN1 LTBP4 NR2F1	2.19e-05	199	37	4	9c2db0bb94cba71a3cc1827844da090e213e0258
ToppCell	Mesenchymal\|World / Lineage, Cell type, age group and donor	FBN1 ABLIM3 LTBP4 NR2F1	2.19e-05	199	37	4	4bac110c2b3609f6ee5d0e3275da0824a6240270
ToppCell	Control_saline-Mesenchymal_fibroblastic-Fibroblasts-Diff_MatrixFB\|Control_saline / Treatment groups by lineage, cell group, cell type	FBN1 ABLIM3 LTBP4 NR2F1	2.19e-05	199	37	4	c2c42ecf20d1924edc2f899c01dfa5fcf3c210b9
ToppCell	Tracheal-NucSeq-Stromal-Peri/Epineurial_\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	SCUBE1 FBN1 LTBP4 NR2F1	2.19e-05	199	37	4	3835452e4848d7f7dd8651c17b746b271ef39688
ToppCell	Control_saline-Mesenchymal_fibroblastic\|Control_saline / Treatment groups by lineage, cell group, cell type	FBN1 ABLIM3 LTBP4 NR2F1	2.23e-05	200	37	4	64ae5cf6cb4fc94cf1052abd82648f6b8e6445fe
ToppCell	LPS_anti-TNF-Mesenchymal_fibroblastic-Fibroblasts\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	FBN1 ABLIM3 LTBP4 NR2F1	2.23e-05	200	37	4	b79628fd1386aa9a3b0e9fa81def0bc100c3c073
ToppCell	LPS_anti-TNF-Mesenchymal_fibroblastic\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	FBN1 ABLIM3 LTBP4 NR2F1	2.23e-05	200	37	4	50ca6550998e461ef26dd670351060bd940765a8
ToppCell	Control_saline-Mesenchymal_fibroblastic-Fibroblasts\|Control_saline / Treatment groups by lineage, cell group, cell type	FBN1 ABLIM3 LTBP4 NR2F1	2.23e-05	200	37	4	a1fc74c1b27e104895910bc7cdce7ba33d30df7e
ToppCell	Control_saline-Endothelial-Endothelial-Vein\|Control_saline / Treatment groups by lineage, cell group, cell type	FBN1 VWF SKIL STAB1	2.23e-05	200	37	4	e5f876910bc8cb390d9b46a48d9b6d4d57235551
ToppCell	LPS_anti-TNF-Mesenchymal_fibroblastic-Fibroblasts-Diff_MatrixFB\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	FBN1 ABLIM3 LTBP4 NR2F1	2.23e-05	200	37	4	3bdba9612cd7c612b76aa9abecc4a6529aabfc1c
ToppCell	Control_saline-Mesenchymal_fibroblastic-Fibroblasts-MatrixFB\|Control_saline / Treatment groups by lineage, cell group, cell type	FBN1 ABLIM3 LTBP4 NR2F1	2.23e-05	200	37	4	bd8cf33502adea320e91ca2af14e1911d88ad374
ToppCell	Control_saline-Endothelial-Endothelial-Artery\|Control_saline / Treatment groups by lineage, cell group, cell type	FBN1 VWF SKIL LTBP4	2.23e-05	200	37	4	65b71f1e8da5c3750fcd0a2e66d9ef3125a3f78a
ToppCell	Tracheal-10x5prime-Endothelial\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	VWF ABLIM3 STC2 STAB1	2.23e-05	200	37	4	71ba0e48ca4ded077f2b96a0cf4f2331f2e25d15
ToppCell	PBMC-Mild-Myeloid-Neutrophil-Neutrophil-Neu_0\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	INSC INSRR HPX	1.78e-04	132	37	3	82f312a561d9fdd2ebc2c25926dfc2b333ff0a4f
ToppCell	PBMC-Mild-Myeloid-Neutrophil-Neutrophil-Neu_0\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	INSC INSRR HPX	1.78e-04	132	37	3	fe87cb22e13e17df29ad43327f1aa71361907582
ToppCell	droplet-Bladder-BLADDER-1m-Epithelial-nan\|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SCUBE1 LTBP4 INSRR	2.12e-04	140	37	3	e442c46979d725ec82f525a001c46d971fcade4d
ToppCell	Smart-seq2-lymph_node_(Smart-seq2)-myeloid-myeloid_monocytic\|lymph_node_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	ABLIM3 STC2 STAB1	2.70e-04	152	37	3	072daae0deb6cb92f126e4566f1d264cda9ed157
ToppCell	Transplant_Alveoli_and_parenchyma-Epithelial-Ciliated_2\|Epithelial / Tissue, Lineage and Cell class of Lung Cells from 10X	ODAD2 NR2F1 HPX	3.14e-04	160	37	3	6de505bfe1fbbe984718740a9cf43d0e02ff452e
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-Degenerative_Endothelial_Cell-Degenerative_Peritubular_Capilary_Endothelial_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	ZBTB46 VWF NOTCH1	3.31e-04	163	37	3	73c03e29a6d7a6863c5e9aa5e8b963ef691f1ddb
ToppCell	facs-Pancreas-Exocrine-18m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	UBR1 CDC14B KPNA3	3.31e-04	163	37	3	132aece9c79499b4bb3c2bde68d3d7202e1d8772
ToppCell	Endothelial-B-Donor_01\|World / lung cells shred on cell class, cell subclass, sample id	FBN1 ABLIM3 NR2F1	3.43e-04	165	37	3	b6893882472aeb0d18e26f47eaec9d53688afcde
ToppCell	PND03-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-AEC-AEC_prolif\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	UBR1 VWF LTBP4	3.43e-04	165	37	3	62457b7b74c6eae42d91d65e7dc6df6bf8e061f7
ToppCell	PND14-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-AEC\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	VWF LTBP4 NOTCH1	3.49e-04	166	37	3	7a45785a40b7425f97be67bab1c5ceb69b2bd85a
ToppCell	PND14-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-AEC-AEC_mature\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	VWF LTBP4 NOTCH1	3.49e-04	166	37	3	bbd382812f8a84a5d99888de2d7cca3a8b5e4695
ToppCell	Adult-Endothelial-alveolar_capillary_endothelial_cell_(Cap2;_aerocyte)-D231\|Adult / Lineage, Cell type, age group and donor	ZBTB46 VWF STC2	3.56e-04	167	37	3	5af9127bae05768a5164d5708a4ad37edca99324
ToppCell	facs-Heart-RA-18m-Endothelial-endothelial_cell_of_endocardium\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	VWF NOTCH1 STAB1	3.62e-04	168	37	3	06dc5b2d356d3a9454b10bba6f3b9ead2a0a7d46
ToppCell	facs-Heart-RA-18m-Endothelial-endocardial_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	VWF NOTCH1 STAB1	3.62e-04	168	37	3	1002f058a340763e3d8de0bd1f0547a903526ec6
ToppCell	RA-01._Fibroblast_I\|RA / Chamber and Cluster_Paper	FBN1 LTBP4 INSRR	3.68e-04	169	37	3	6373562ab3b1765060212a6a53d6543e7e942e80
ToppCell	5'-Adult-LargeIntestine-Mesenchymal-fibroblastic-Stromal_1_(ADAMDEC1+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	FBN1 LTBP4 NR2F1	3.68e-04	169	37	3	c0824a93674e2bff0f09b2d2fab5bab016a2e379
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell_of_renal_medulla-lymphatic_endothelial_cell_of_renal_medulla\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	FBN1 ABLIM3 LTBP4	3.75e-04	170	37	3	dcc64b73134e89ae37990d4878813b86ce91dae9
ToppCell	E17.5-Mesenchymal-developing_mesenchymal_cell-mesenchymal_immature_unknown_1\|E17.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	FBN1 VWF ABLIM3	3.75e-04	170	37	3	7fa022471e14ac8a3bc147c793368a4d56a8e591
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Endothelial-lymphatic_endothelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	FBN1 ABLIM3 LTBP4	3.75e-04	170	37	3	6035c92cd39c5ac54e7ec57d94888ee19f574639
ToppCell	facs-Brain_Myeloid-Striatum-24m-Myeloid-nan\|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LAMA3 CD164L2 STC2	3.75e-04	170	37	3	ca88dc0b7a6960facb7c4d3c0f4795431a0a43d2
ToppCell	3'-GW_trimst-1.5-LargeIntestine-Mesenchymal-fibroblastic-Stromal_1_(ADAMDEC1+)\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	RPL10A SCUBE1 LTBP4	3.75e-04	170	37	3	b5b47fe42617a4c2ebb49c8ed55db3926213a75a
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell_of_renal_medulla\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	FBN1 ABLIM3 LTBP4	3.75e-04	170	37	3	c8c42eda44b61440c96b202e7f54650046eb95d3
ToppCell	facs-Brain_Myeloid-Striatum-24m-Myeloid\|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LAMA3 CD164L2 STC2	3.75e-04	170	37	3	b6882665a27c78a63f3b4a2a8806c8438a98e407
ToppCell	facs-Brain_Myeloid-Striatum-24m-Myeloid-microglial_cell\|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LAMA3 CD164L2 STC2	3.75e-04	170	37	3	626c12b9a51218f72ee32afb5fd5d4b075025d75
ToppCell	facs-Brain_Myeloid-Striatum-24m\|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LAMA3 CD164L2 STC2	3.75e-04	170	37	3	31daac8696ae8c021c0302d3b30dd8194054b3e7
ToppCell	TCGA-Liver-Primary_Tumor-Hepatocellular_Carcinoma-Hepatocellular_Carcinoma-8\|TCGA-Liver / Sample_Type by Project: Shred V9	SCUBE1 VWF HPX	3.81e-04	171	37	3	c4a919fe3d56ae6df2fcab6686abacc10befc053
ToppCell	390C-Lymphocytic-ILC\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	UBAP2 MPND KRT85	3.81e-04	171	37	3	70963f79711fe6088d6d01b29206b17ab89e5e73
ToppCell	E16.5-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-VEC-VEC_prolif\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	UBAP2 VWF SKIL	3.88e-04	172	37	3	8a6a2b4c6654bc976e60a02d0e7303a9071ed55f
ToppCell	Children_(3_yrs)-Mesenchymal-myofibroblast_cell-D046\|Children_(3_yrs) / Lineage, Cell type, age group and donor	SCUBE1 FBN1 NR2F1	3.94e-04	173	37	3	1f16d47f5548e257e4b17f8070c5619780a9c5fd
ToppCell	Adult-Mesenchymal-pericyte_cell-D175\|Adult / Lineage, Cell type, age group and donor	ZBTB46 INSC NR2F1	3.94e-04	173	37	3	fd6653d6be9ca6ac36798590694efe03cb758c67
ToppCell	PND01-03-samps-Endothelial-Postnatal_endothelial-endothelial_cells_D\|PND01-03-samps / Age Group, Lineage, Cell class and subclass	INSC NOTCH1 STAB1	4.01e-04	174	37	3	b4f3f5334803e5903bc496decf923f2e44f7fa3c
ToppCell	facs-Heart-RA-24m-Endothelial-endothelial_cell_of_endocardium\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	VWF NOTCH1 STAB1	4.01e-04	174	37	3	42dfb6f42b72e40e203b3ef341117bccf3553d54
ToppCell	facs-Heart-RA-24m-Endothelial-endocardial_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	VWF NOTCH1 STAB1	4.01e-04	174	37	3	f04edf2ca6788875c9918611e416fb739924382e
Disease	mesangial proliferative glomerulonephritis (biomarker_via_orthology)	FBN1 VWF	4.26e-05	8	37	2	DOID:4783 (biomarker_via_orthology)
Disease	Glioblastoma Multiforme	LTBP4 NOTCH1 INSRR	3.67e-04	111	37	3	C1621958
Disease	peripheral neuropathy, response to antimicrotubule agent	SCUBE1 SLITRK1	3.81e-04	23	37	2	EFO_0003100, EFO_0005260
Disease	response to peginterferon alfa-2a	VWF CDC14B	4.51e-04	25	37	2	EFO_0010103
Disease	prostate carcinoma	ZBTB46 ACAA2 UBAP2 ODAD2 SKIL INSC	7.78e-04	891	37	6	EFO_0001663

Protein segments in the cluster

Peptide	Gene	Start	Entry
CGDTCKGEVVRVHNN	ABLIM3	26	O94929
DICENAEGAIAVHCK	CDC14B	301	O60729
DICENAEGAIAVHCK	CDC14C	271	A4D256
CIIEKGEEHCGHLIE	COX17	36	Q14061
PQVVEACCQFIEKHG	ARHGAP36	236	Q6ZRI8
QQHIECVVCGDKSSG	NR2F1	81	P10589
CGGLEKIEVLQQHEN	KPNA3	456	O00505
CGQQPVVEKCETIHV	LARGE1	126	O95461
RGTQGVHCEINVDDC	NOTCH1	1211	P46531
GVCQCREHVVGKVCQ	LAMA3	701	Q16787
EHRLCEGVGSVNVCV	KRT85	431	P78386
GVKGDECQLCEVENR	ATRN	1131	O75882
LCHVLEQVCGVLKQG	MPND	456	Q8N594
TDINECEIGAHNCGK	FBN1	1321	P35555
HEQEVNCVDCKGGII	FBXW4	201	P57775
GRHCVDVNECETLQG	LTBP4	1086	Q8N2S1
HIVGNKLGEECADVC	INSRR	166	P14616
ASICCVEEGVHQLEK	INSC	306	Q1MX18
QLEVCEHCVEGDGAR	CD164L2	56	Q6UWJ8
GHCVAQSEVVKEGCS	CD164L2	86	Q6UWJ8
LCGEQVHILGCEVSE	ELP5	51	Q8TE02
KDINECLVNNGGCDH	SCUBE1	281	Q8IWY4
AVECHRGECQAEGVL	HPX	146	P02790
EGIVCQDDQVCQKGC	SSPOP	4086	A2VEC9
AFEVEHECLGKCQGL	SKIL	261	P12757
GNVQQVVHLCLECEK	TDRD12	646	Q587J7
EVLVNVVGALGECCQ	ODAD2	771	Q5T2S8
NGCQEICVKEAEVVL	ACAA2	101	P42765
KNQDECIVALHDCNG	UBAP2	66	Q5T6F2
EEACTQCIGEDGVQH	VWF	2251	P04275
EKICSCNEIEGDLHV	SLITRK1	26	Q96PX8
AEIQHCLVNAGDVGC	STC2	51	O76061
CQEIVNGEEVGACIF	UBR1	1641	Q8IWV7
EEQHKIVAGSCVDCQ	STAB1	656	Q9NY15
CVLGDQQHCDEAKAV	RPL10A	66	P62906
VAEGIKIGIQECQHQ	WNT3A	66	P56704
ICQEHCQISGQAKID	SOHLH2	6	Q9NX45
QHGVLCDVCVVVEGK	ZBTB46	26	Q86UZ6