Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionstructural constituent of eye lens

CRYBA1 CRYBB1

3.15e-0424222GO:0005212
GeneOntologyMolecularFunctionsymporter activity

SLC6A5 SLC16A4 SLC6A4

5.76e-04150223GO:0015293
GeneOntologyMolecularFunctionantigen binding

IGHV4-61 IGHV4-59 IGHV4-28

1.14e-03190223GO:0003823
GeneOntologyMolecularFunctionsolute:sodium symporter activity

SLC6A5 SLC6A4

3.56e-0381222GO:0015370
GeneOntologyMolecularFunctionsecondary active transmembrane transporter activity

SLC6A5 SLC16A4 SLC6A4

4.03e-03296223GO:0015291
DomainBeta/gamma_crystallin

CRYBA1 CRYBB1

1.02e-0415192IPR001064
DomainCrystall

CRYBA1 CRYBB1

1.02e-0415192PF00030
DomainXTALbg

CRYBA1 CRYBB1

1.02e-0415192SM00247
DomainCRYSTALLIN_BETA_GAMMA

CRYBA1 CRYBB1

1.02e-0415192PS50915
DomainG_crystallin-rel

CRYBA1 CRYBB1

1.49e-0418192IPR011024
DomainNA_NEUROTRAN_SYMP_2

SLC6A5 SLC6A4

1.49e-0418192PS00754
DomainSNF

SLC6A5 SLC6A4

1.66e-0419192PF00209
DomainNA_NEUROTRAN_SYMP_3

SLC6A5 SLC6A4

1.66e-0419192PS50267
DomainNa/ntran_symport

SLC6A5 SLC6A4

1.66e-0419192IPR000175
DomainNA_NEUROTRAN_SYMP_1

SLC6A5 SLC6A4

1.66e-0419192PS00610
DomainGlycoside_hydrolase_SF

HYAL4 MANEA

1.31e-0353192IPR017853
DomainEGF

HYAL4 NTNG1

2.34e-02235192SM00181
DomainEGF_1

HYAL4 NTNG1

2.73e-02255192PS00022
PathwayREACTOME_CD22_MEDIATED_BCR_REGULATION

IGHV4-61 IGHV4-59 IGHV4-28

7.68e-0635163MM17219
PathwayREACTOME_CLASSICAL_ANTIBODY_MEDIATED_COMPLEMENT_ACTIVATION

IGHV4-61 IGHV4-59 IGHV4-28

1.07e-0539163MM17212
PathwayREACTOME_IMMUNOREGULATORY_INTERACTIONS_BETWEEN_A_LYMPHOID_AND_A_NON_LYMPHOID_CELL

IGHV4-61 IGHV4-59 IGHV4-28 SIGLEC6

1.34e-05135164MM14781
PathwayREACTOME_ROLE_OF_LAT2_NTAL_LAB_ON_CALCIUM_MOBILIZATION

IGHV4-61 IGHV4-59 IGHV4-28

1.65e-0545163MM14912
PathwayREACTOME_FCGR_ACTIVATION

IGHV4-61 IGHV4-59 IGHV4-28

2.01e-0548163MM17214
PathwayREACTOME_ANTIGEN_ACTIVATES_B_CELL_RECEPTOR_BCR_LEADING_TO_GENERATION_OF_SECOND_MESSENGERS

IGHV4-61 IGHV4-59 IGHV4-28

2.71e-0553163MM15716
PathwayREACTOME_INITIAL_TRIGGERING_OF_COMPLEMENT

IGHV4-61 IGHV4-59 IGHV4-28

2.87e-0554163MM14655
PathwayREACTOME_ROLE_OF_PHOSPHOLIPIDS_IN_PHAGOCYTOSIS

IGHV4-61 IGHV4-59 IGHV4-28

3.21e-0556163MM14815
PathwayREACTOME_FCERI_MEDIATED_CA_2_MOBILIZATION

IGHV4-61 IGHV4-59 IGHV4-28

3.56e-0558163MM14914
PathwayREACTOME_BINDING_AND_UPTAKE_OF_LIGANDS_BY_SCAVENGER_RECEPTORS

IGHV4-61 IGHV4-59 IGHV4-28

3.95e-0560163MM14872
PathwayREACTOME_FCERI_MEDIATED_MAPK_ACTIVATION

IGHV4-61 IGHV4-59 IGHV4-28

3.95e-0560163MM14913
PathwayREACTOME_COMPLEMENT_CASCADE

IGHV4-61 IGHV4-59 IGHV4-28

1.08e-0484163MM14653
PathwayREACTOME_FCERI_MEDIATED_NF_KB_ACTIVATION

IGHV4-61 IGHV4-59 IGHV4-28

2.22e-04107163MM14915
PathwayREACTOME_FCGAMMA_RECEPTOR_FCGR_DEPENDENT_PHAGOCYTOSIS

IGHV4-61 IGHV4-59 IGHV4-28

2.67e-04114163MM14814
PathwayREACTOME_SIGNALING_BY_THE_B_CELL_RECEPTOR_BCR

IGHV4-61 IGHV4-59 IGHV4-28

4.02e-04131163MM15717
PathwayREACTOME_FC_EPSILON_RECEPTOR_FCERI_SIGNALING

IGHV4-61 IGHV4-59 IGHV4-28

5.97e-04150163MM14889
PathwayREACTOME_CELL_SURFACE_INTERACTIONS_AT_THE_VASCULAR_WALL

IGHV4-61 IGHV4-59 IGHV4-28

6.95e-04158163MM14812
PathwayREACTOME_POST_TRANSLATIONAL_MODIFICATION_SYNTHESIS_OF_GPI_ANCHORED_PROTEINS

NTNG1 CPM

4.87e-0393162M26985
PathwayREACTOME_VESICLE_MEDIATED_TRANSPORT

IGHV4-61 IGHV4-59 IGHV4-28 DNASE2

5.09e-03645164MM15232
Pubmed

Cloning, sequencing and expression of the rearranged MOPC 315 VH gene segment.

IGHV4-61 IGHV4-59 IGHV4-28

7.68e-0972232497341
Pubmed

The idiotypic network and the internal image: possible regulation of a germ-line network by paucigene encoded Ab2 (anti-idiotypic) antibodies in the GAT system.

IGHV4-61 IGHV4-59 IGHV4-28

7.68e-0972233937730
Pubmed

Model-building studies of antigen-binding sites: the hapten-binding site of mopc-315.

IGHV4-61 IGHV4-59 IGHV4-28

7.68e-097223268248
Pubmed

The structure of the expressible VH gene from a hybridoma producing monoclonal antibodies against porcine transferrin.

IGHV4-61 IGHV4-59 IGHV4-28

7.68e-0972232587273
Pubmed

Amino acid sequence of the precursor region of MOPC-315 mouse immunoglobulin heavy chain.

IGHV4-61 IGHV4-59 IGHV4-28

7.68e-097223414225
Pubmed

A new germline VH36-60 gene is used in the neonatal primary and adult memory response to (T,G)-A--L.

IGHV4-61 IGHV4-59 IGHV4-28

7.68e-0972231683681
Pubmed

Amino-acid sequence of the variable region of the heavy (alpha) chain of a mouse myeloma protein with anti-hapten activity.

IGHV4-61 IGHV4-59 IGHV4-28

7.68e-0972234524622
Pubmed

Structure and function of immunoglobulin genes and precursors.

IGHV4-61 IGHV4-59 IGHV4-28

2.63e-0810223428562
Pubmed

Early onset of somatic mutation in immunoglobulin VH genes during the primary immune response.

IGHV4-61 IGHV4-59 IGHV4-28

3.36e-07222232499654
Pubmed

Truncated human betaB1-crystallin shows altered structural properties and interaction with human betaA3-crystallin.

CRYBA1 CRYBB1

3.82e-07222219548648
Pubmed

Association properties of betaB1- and betaA3-crystallins: ability to form heterotetramers.

CRYBA1 CRYBB1

3.82e-07222218823128
Pubmed

The benefits of being β-crystallin heteromers: βB1-crystallin protects βA3-crystallin against aggregation during co-refolding.

CRYBA1 CRYBB1

3.82e-07222222032798
Pubmed

Influence of 5-HTTLPR polymorphism on resting state perfusion in patients with major depression.

SLC6A5 SLC6A4

3.82e-07222220934189
Pubmed

Deamidation alters interactions of beta-crystallins in hetero-oligomers.

CRYBA1 CRYBB1

1.15e-06322219190732
Pubmed

Impact of Maternal Serotonin Transporter Genotype on Placental Serotonin, Fetal Forebrain Serotonin, and Neurodevelopment.

SLC6A4 NTNG1

1.15e-06322227550733
Pubmed

Linkage and association analyses of intragenic SNPs in the canine beta-crystallin genes CRYBB1, CRYBB2, CRYBB3, CRYBA1 and CRYBA4 with primary cataracts in wire-haired Dachshunds.

CRYBA1 CRYBB1

2.29e-06422218162101
Pubmed

Overlapping effects of different members of the FGF family on lens fiber differentiation in transgenic mice.

CRYBA1 CRYBB1

5.72e-0662229693140
Pubmed

Assignment of the beta B1 crystallin gene (CRYBB1) to human chromosome 22 and mouse chromosome 5.

CRYBA1 CRYBB1

8.01e-0672228575764
Pubmed

A transient placental source of serotonin for the fetal forebrain.

SLC6A4 NTNG1

8.01e-06722221512572
Pubmed

IMGT/GENE-DB: a comprehensive database for human and mouse immunoglobulin and T cell receptor genes.

IGHV4-61 IGHV4-59 IGHV4-28

1.56e-057722315608191
Pubmed

Lens-specific conditional knockout of Msx2 in mice leads to ocular anterior segment dysgenesis via activation of a calcium signaling pathway.

CRYBA1 CRYBB1

1.71e-051022230683901
Pubmed

The upstream ectoderm enhancer in Pax6 has an important role in lens induction.

CRYBA1 CRYBB1

2.09e-051122211714668
Pubmed

Shotgun identification of protein modifications from protein complexes and lens tissue.

CRYBA1 CRYBB1

2.09e-051122212060738
Pubmed

The complete nucleotide sequence of the human immunoglobulin heavy chain variable region locus.

IGHV4-61 IGHV4-59 IGHV4-28

2.57e-05912239841928
Pubmed

Plasticity of thalamocortical axons is regulated by serotonin levels modulated by preterm birth.

SLC6A4 NTNG1

2.97e-051322237549297
Pubmed

The orchestration of mammalian tissue morphogenesis through a series of coherent feed-forward loops.

CRYBA1 CRYBB1

3.46e-051422221998302
Pubmed

Prox1 function is crucial for mouse lens-fibre elongation.

CRYBA1 CRYBB1

3.99e-051522210080188
Pubmed

Unique contribution of heat shock transcription factor 4 in ocular lens development and fiber cell differentiation.

CRYBA1 CRYBB1

4.56e-051622215593327
Pubmed

Regulation of mouse lens fiber cell development and differentiation by the Maf gene.

CRYBA1 CRYBB1

5.16e-051722210603348
Pubmed

Barhl2 Determines the Early Patterning of the Diencephalon by Regulating Shh.

SLC6A4 NTNG1

7.21e-052022227349434
Pubmed

The repertoire of solute carriers of family 6: identification of new human and rodent genes.

SLC6A5 SLC6A4

7.96e-052122216125675
Pubmed

Draxin from neocortical neurons controls the guidance of thalamocortical projections into the neocortex.

SLC6A4 NTNG1

9.59e-052322226659141
Pubmed

Sox2 Acts in Thalamic Neurons to Control the Development of Retina-Thalamus-Cortex Connectivity.

SLC6A4 NTNG1

9.59e-052322231082736
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

NTNG1 BIRC6 SUN2 SSH2

2.38e-0449322415368895
Cytoband17q11.2

CRYBA1 SLC6A4 SSH2

1.99e-0511022317q11.2
CytobandEnsembl 112 genes in cytogenetic band chr17q11

CRYBA1 SLC6A4 SSH2

7.42e-05171223chr17q11
Cytoband14q32.33

IGHV4-61 IGHV4-59 IGHV4-28

1.74e-0422822314q32.33
Cytoband1p13.3

SLC16A4 NTNG1

5.04e-04692221p13.3
CytobandEnsembl 112 genes in cytogenetic band chr14q32

IGHV4-61 IGHV4-59 IGHV4-28

2.41e-03566223chr14q32
CytobandEnsembl 112 genes in cytogenetic band chr1p13

SLC16A4 NTNG1

4.57e-03211222chr1p13
CytobandEnsembl 112 genes in cytogenetic band chr22q13

PKDREJ SUN2

1.08e-02330222chr22q13
GeneFamilyBeta-gamma crystallins

CRYBA1 CRYBB1

5.81e-05151421359
GeneFamilyImmunoglobulin heavy locus at 14q32.33

IGHV4-61 IGHV4-59 IGHV4-28

3.64e-04187143349
GeneFamilySolute carriers

SLC6A5 SLC16A4 SLC6A4

3.15e-03395143752
ToppCellControl-Control-Lymphocyte-B-Plasmablast|Control / Disease, condition lineage and cell class

CRYBB1 IGHV4-61 IGHV4-59 MANEA IGHV4-28

3.99e-08199225c11aa8bca3723a886e7082ae48bb922dd8396be4
ToppCellhealthy_donor-Lymphocytic-Plasma_cell-IgM_Plasmablast|healthy_donor / Disease condition, Lineage, Cell class and subclass

IGHV4-61 IGHV4-59 MANEA IGHV4-28

1.24e-061662242b7b580bec8d9467b0deaf97098065f72dbf2a4f
ToppCellmetastatic_Brain-B_lymphocytes-Plasma_cells|metastatic_Brain / Location, Cell class and cell subclass

IGHV4-61 IGHV4-59 MANEA IGHV4-28

1.36e-0617022453634da9e9c72f6400639954c286c6e38ea5a188
ToppCell5'-Parenchyma_lung-Immune_Lymphocytic-Lymphocytic_B-plasma_cell-Plasma_cells-Plasma_cells_L.1.7.0.1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

IGHV4-61 IGHV4-59 CERCAM IGHV4-28

1.75e-06181224e47664a264a2c37390d1668ce04eef2e0172f4cb
ToppCellBAL-Mild-Lymphocyte-B|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)

IGHV4-61 IGHV4-59 IGHV4-28 SIGLEC6

1.75e-06181224700adfb41e4e377530f0dd31be89e12f109f3469
ToppCell10x5'-Lung-Lymphocytic_B|Lung / Manually curated celltypes from each tissue

NTNG1 IGHV4-61 IGHV4-59 IGHV4-28

1.79e-06182224310f94437d197eaaaf6e30e68063b33e94befe77
ToppCellMild-Lymphoid-B|Mild / Condition, Lineage, Cell class and cell subclass

IGHV4-61 IGHV4-59 IGHV4-28 SIGLEC6

1.83e-061832249b64d2d143525e6f48a191facfd101462ff36324
ToppCell368C-Lymphocytic-Plasma_cell-|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

IGHV4-61 IGHV4-59 CERCAM MANEA

1.83e-06183224d91441cbf94f5c3b7c36f2ca3a46895870bd730f
ToppCellMild_COVID-19-B_cell|Mild_COVID-19 / Disease group,lineage and cell class （2021.01.30）

IGHV4-61 IGHV4-59 IGHV4-28 SIGLEC6

1.83e-06183224dea119e2988e954475f557f0bbe12556a83e81a4
ToppCell368C-Lymphocytic-Plasma_cell|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

IGHV4-61 IGHV4-59 CERCAM MANEA

1.83e-061832247733cf919eda146efe41c93990658ce92db73aa8
ToppCellMild-Lymphoid-B-|Mild / Condition, Lineage, Cell class and cell subclass

IGHV4-61 IGHV4-59 IGHV4-28 SIGLEC6

1.83e-06183224b5740f05a4dcdbbf24f7bf7a3f57ac01a5e75f60
ToppCellBAL-Mild-Lymphocyte-B-B_cell-B_cell|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

IGHV4-61 IGHV4-59 IGHV4-28 SIGLEC6

1.87e-061842243f8a359e40bebe58545f708682e5e5d1b70cf5cb
ToppCell10x5'-Liver-Lymphocytic_B_plasma-Plasma_cells|Liver / Manually curated celltypes from each tissue

IGHV4-61 IGHV4-59 MANEA IGHV4-28

1.87e-061842246f70d8f8ab8362d51f8a58735d42223e06566397
ToppCellBAL-Mild-Lymphocyte-B-B_cell-B_cell-|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

IGHV4-61 IGHV4-59 IGHV4-28 SIGLEC6

1.87e-0618422464bede8db709fd32f40c03265b96f0b12155bb8a
ToppCellBAL-Mild-Lymphocyte-B-B_cell|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)

IGHV4-61 IGHV4-59 IGHV4-28 SIGLEC6

1.91e-06185224609080adb2cfb105bb7b8efb617553833299f371
ToppCellMild_COVID-19-B_cell-B_cell|Mild_COVID-19 / Disease group,lineage and cell class （2021.01.30）

IGHV4-61 IGHV4-59 IGHV4-28 SIGLEC6

1.95e-06186224855a5a00ba2aa1b5c63b8db56d026ddecc546050
ToppCellSmart-seq2-tissue-resident_(Smart-seq2)-lymphocytic-B_lymphocytic-plasma_cell|tissue-resident_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

IGHV4-61 IGHV4-59 CERCAM IGHV4-28

1.99e-06187224c80e03d5aa498b4eecbc46565fabf9b5be10c71c
ToppCellhealthy_donor-Lymphocytic-Plasma_cell|healthy_donor / Disease condition, Lineage, Cell class and subclass

IGHV4-61 IGHV4-59 MANEA IGHV4-28

2.04e-06188224bd53b0371154cff680226897b61c9809a239d1b6
ToppCellPBMC-Mild-Lymphocyte-B-Plasmablast-Plasmablast|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

CRYBB1 IGHV4-59 MANEA IGHV4-28

2.08e-0618922473ee4cfb1057832f700be59b6917dedde3e89880
ToppCellPBMC-Mild-Lymphocyte-B-Plasmablast|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

CRYBB1 IGHV4-59 MANEA IGHV4-28

2.08e-06189224f2daf4889ef98bbefe3e44832618ac102a75b4d9
ToppCell5'-Adult-LargeIntestine-Hematopoietic-Plasma_cells|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

IGHV4-61 IGHV4-59 MANEA IGHV4-28

2.12e-0619022479ee6d10dfbb775da149a1104da5823cf63bbb46
ToppCell5'-Adult-LargeIntestine-Hematopoietic-Plasma_cells-IgA_plasma_cell|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

IGHV4-61 IGHV4-59 MANEA IGHV4-28

2.12e-0619022418762ce78ed0b206ade19e1c8ff76a2647489f68
ToppCellCOVID_non-vent-Lymphocytic-Plasma_cell-IgM_Plasmablast|COVID_non-vent / Disease condition, Lineage, Cell class and subclass

IGHV4-61 IGHV4-59 MANEA IGHV4-28

2.26e-061932247b4b0271e4fbece703876acb053ae236afb7cdba
ToppCellBiopsy_Other_PF-Immune-Plasma_cells|Biopsy_Other_PF / Sample group, Lineage and Cell type

IGHV4-61 IGHV4-59 MANEA IGHV4-28

2.35e-06195224d0305c6a68c9e361507b04db94f86873085d49b3
ToppCellCOVID_vent-Lymphocytic-Plasma_cell-IgM_Plasmablast|COVID_vent / Disease condition, Lineage, Cell class and subclass

IGHV4-61 IGHV4-59 MANEA IGHV4-28

2.40e-06196224026a06d8d2089806823e6f6453d3ede84ae93bc6
ToppCellCOVID_non-vent-Lymphocytic-Plasma_cell-IgA_Plasmablast|COVID_non-vent / Disease condition, Lineage, Cell class and subclass

IGHV4-61 IGHV4-59 MANEA IGHV4-28

2.45e-06197224fdbf4eb9fa5aefb4ffb307494fe4774bf5e0aaeb
ToppCellCOVID_non-vent-Lymphocytic-Plasma_cell|COVID_non-vent / Disease condition, Lineage, Cell class and subclass

IGHV4-61 IGHV4-59 MANEA IGHV4-28

2.45e-061972241e63879633f20646e44873ae6b662f6faf4806fd
ToppCellCOVID_non-vent-Lymphocytic-Plasma_cell-IgG_Plasmablast|COVID_non-vent / Disease condition, Lineage, Cell class and subclass

IGHV4-61 IGHV4-59 MANEA IGHV4-28

2.45e-06197224b754fad4f3caae6de95df901fd96ea8697fe41b1
ToppCellLPS-antiTNF-Myeloid-Dendritic_cells-Monocytes-Macrophages|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CRYBB1 DNASE2 CPM

3.33e-05128223cfc73cb803ba50a4a8709e19e70e1e399118c849
ToppCell390C-Lymphocytic-Plasma_cell|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

NTNG1 CRYBB1 IGHV4-59

7.21e-051662234ba3711a02d3695b27f7cefd7c60e3be009f5bef
ToppCell390C-Lymphocytic-Plasma_cell-|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

NTNG1 CRYBB1 IGHV4-59

7.21e-0516622335f6ae2664935dda0d883b32a050ced843204f2d
ToppCell10x5'-GI_large-bowel|World / Manually curated celltypes from each tissue

IGHV4-61 IGHV4-59 IGHV4-28

7.48e-051682231290c909655bc37f6b8bf216d18127a21b99e9c0
ToppCellBAL-Mild-Lymphocyte-B|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

IGHV4-61 IGHV4-59 SIGLEC6

7.61e-05169223307571e57c3bfdf15f0fe1a8b36585e8e4f8a207
ToppCellBAL-Mild-Lymphocyte-B-B_cell-B_cell-B_activate-7|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

IGHV4-61 IGHV4-59 SIGLEC6

7.74e-05170223ee2ee67d90ae4596de8ccd620e37c82cf51651d4
ToppCellBAL-Mild-Lymphocyte-B-B_cell-B_cell|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

IGHV4-61 IGHV4-59 SIGLEC6

7.74e-05170223d7ca0c6ce5d2b7de99346f87e07aa7fe728fa08a
ToppCellBAL-Mild-Lymphocyte-B-B_cell|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

IGHV4-61 IGHV4-59 SIGLEC6

7.74e-0517022352787f6d529c285d9f0c04cc022710ead5b89b3f
ToppCellPND03-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF1-AF1_prolif|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

DPT PRIM1 CPM

7.74e-05170223e20568c8f3f17d94de78229617eb2f7e4c5af2bc
ToppCellsystemic_lupus_erythematosus-flare-Lymphocytic_NK-natural_killer_cell-male|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

SLC6A4 CERCAM SUN2

8.01e-0517222368fd03f2c8ee01fe46194400f74ede3830e00f34
ToppCell10x5'-Lung-Lymphocytic_B-Memory_B_cells|Lung / Manually curated celltypes from each tissue

NTNG1 IGHV4-59 IGHV4-28

8.01e-051722232cb2dc7cfd6db5a98a393b1a84c23abf3d692a53
ToppCell5'-Parenchyma_lung-Immune_Lymphocytic-Lymphocytic_B-plasma_cell-Plasma_cells-Plasma_cells_L.1.7.0.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

IGHV4-61 IGHV4-59 IGHV4-28

8.15e-051732237e6bfe85f60834f317941b70d6e0dc3bd527d293
ToppCellE16.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-Chondrocyte|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SLC16A4 BIRC6 CERCAM

8.44e-051752238b498eea1ec1c1f27b171025c3d08adf3687bafc
ToppCellwk_15-18-Hematologic_Lymphocytic-B-CD5+_CCL22+_mature_B|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

IGHV4-61 IGHV4-59 IGHV4-28

8.44e-05175223fa53ea81ad943a2cd266114829135cbcbcf2f634
ToppCellE16.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-Chondrocyte-Chondrocyte_mature|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SLC16A4 BIRC6 CERCAM

8.44e-05175223a5db428b078938627e61b7e944c1e0c1d61ac2da
ToppCell3'_v3-bone_marrow-Lymphocytic_B_plasma-Plasma_cells|bone_marrow / Manually curated celltypes from each tissue

IGHV4-59 CERCAM IGHV4-28

8.44e-0517522351301f3f44d3e88397f367cedd1e2abaa2be4c6f
ToppCellmetastatic_Brain-B_lymphocytes-MALT_B_cells|metastatic_Brain / Location, Cell class and cell subclass

IGHV4-61 IGHV4-59 IGHV4-28

8.58e-0517622350e207403d48ce1b55a78897adb5519a2430a626
ToppCellControl-Lymphoid_P|Control / Disease group, lineage and cell class

IGHV4-61 IGHV4-59 MANEA

8.58e-05176223d895a6b295cd649273ff80ad7785a3e0ae4c728a
ToppCellPND07-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF1-AF1_prolif|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

DPT PRIM1 CPM

8.58e-05176223cb8fd56a4f935cdda19d7ab43382cdda7c307667
ToppCellControl-Lymphoid_P-Plasmablast|Control / Disease group, lineage and cell class

IGHV4-61 IGHV4-59 MANEA

8.58e-051762234b4416f342b732d2cc60133838728880326257d8
ToppCellPBMC-Control-Lymphocyte-B-Plasmablast-Plasmablast-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

IGHV4-61 IGHV4-59 MANEA

8.72e-051772234c434a7b7cc54cf4dac996bbc3f5124d9ef9a9cd
ToppCellPBMC-Control-Lymphocyte-B-Plasmablast|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

IGHV4-61 IGHV4-59 MANEA

8.72e-05177223fc40918825b7e1eb6861df59dfca944778a64b98
ToppCellfacs-Thymus-Epithelium-3m-Myeloid|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MANEA DNASE2 CPM

8.72e-051772230e9e44119653abfd270e602e5e477a15e774638f
ToppCellHealthy-Plasmablast|Healthy / disease group, cell group and cell class

IGHV4-61 IGHV4-59 MANEA

8.72e-051772234ff75c609ac9edf7a94bda42eb7124c559e8b6aa
ToppCellfacs-Thymus-Epithelium-3m-Myeloid-macrophage|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MANEA DNASE2 CPM

8.72e-05177223c2b8a3a149d70f77612759dea34df9e43953c566
ToppCellfacs-Thymus-Epithelium-3m-Myeloid-macrophage|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MANEA DNASE2 CPM

8.72e-05177223384f841aa7b2d05815af7885e481f5affc55d897
ToppCellPBMC-Control-Lymphocyte-B-Plasmablast-Plasmablast|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

IGHV4-61 IGHV4-59 MANEA

8.72e-05177223d746122bf8d208c3aa4d156e8c12d0a0e555c6e5
ToppCell5'-Parenchyma_lung-Immune_Lymphocytic-Lymphocytic_B|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

IGHV4-61 IGHV4-59 IGHV4-28

8.87e-05178223107dae8b00c4257697a63700e72bb434cdb8406f
ToppCellPBMC-Control-Lymphocyte-B-Plasmablast|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

IGHV4-61 IGHV4-59 MANEA

9.02e-05179223837ed81f18257f444eaeadc4fac89deedd4e3061
ToppCellPBMC-Control-Lymphocyte-B-Plasmablast-Plasmablast-Plasmablast|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

IGHV4-61 IGHV4-59 MANEA

9.02e-05179223494febe77c6d4e6a2c6f0928bbf4c84b0301f188
ToppCellPBMC-Control-Lymphocyte-B-Plasmablast-Plasmablast|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

IGHV4-61 IGHV4-59 MANEA

9.02e-05179223b6ee4f41d8fb5f047b7bdd8489dda0a89fc6d43f
ToppCell5'-Parenchyma_lung-Immune_Lymphocytic-Lymphocytic_B-plasma_cell-Plasma_cells-Plasma_cells_L.1.7.1.1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

IGHV4-61 IGHV4-59 MANEA

9.17e-05180223e3877f6ef5f54ff689058b4c996ab1851822f871
ToppCellfacs-Spleen-nan-3m|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DPT SUN2 SSH2

9.17e-05180223c0c3144011856d005aebd5cdc79f89fee32083a8
ToppCellBAL-Severe-Lymphocyte-B-Plasmablast-Plasmablast-Plasmablast|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

IGHV4-61 IGHV4-59 IGHV4-28

9.17e-051802236a777a308fa3160d31eda468db930e71862020b2
ToppCell3'-Child09-12-SmallIntestine-Hematopoietic-Plasma_cells-IgG_plasma_cell|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

IGHV4-61 MANEA IGHV4-28

9.17e-05180223588461d603dafa74e274a1dea021fd568e7f7875
ToppCellfacs-Spleen-nan-3m-Lymphocytic|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DPT SUN2 SSH2

9.17e-0518022387fb1fdbc49c808bb5f6fe9fb747057b45fa78d0
ToppCell10x5'-GI_small-bowel-Lymphocytic_B_plasma|GI_small-bowel / Manually curated celltypes from each tissue

CERCAM MANEA IGHV4-28

9.32e-051812239b33f531c8ac776706ec7e2d47e95ba30b6ce13c
ToppCell10x5'-GI_small-bowel-Lymphocytic_B_plasma-Plasma_cells|GI_small-bowel / Manually curated celltypes from each tissue

CERCAM MANEA IGHV4-28

9.32e-05181223a0549a8c2b5b30e91fae3052f398e48baa45d7ff
ToppCell10x_3'_v3-tissue-resident_(10x_3'_v3)-lymphocytic-B_lymphocytic-plasma_cell|tissue-resident_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

IGHV4-61 IGHV4-59 IGHV4-28

9.32e-05181223f7b08f662eb77ee7a777c6525ddc3195046aaf65
ToppCell10x5'-lymph-node_spleen-Lymphocytic_B_plasma-Plasma_cells|lymph-node_spleen / Manually curated celltypes from each tissue

IGHV4-59 CERCAM MANEA

9.63e-05183223a6866951866373a1029e04818f4a4a31278c409d
ToppCellcellseq-Immune-Lymphocytic_B-Lymphocytic_B-Plasma|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

IGHV4-61 IGHV4-59 IGHV4-28

9.63e-051832235ab4aa0304b832f98fff89b6c24ad5b7dd014c11
ToppCell10x5'-GI_large-bowel-Lymphocytic_B_plasma-Plasma_cells|GI_large-bowel / Manually curated celltypes from each tissue

IGHV4-59 CERCAM IGHV4-28

9.94e-051852232cad994207c4afc9d70f4c2d243ffbbcdbba693e
ToppCell5'-Parenchyma_lung-Immune_Lymphocytic-Lymphocytic_B-plasma_cell-Plasma_cells|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

IGHV4-61 IGHV4-59 IGHV4-28

9.94e-0518522308bc817908076734d66f2805cb954141f2cc5a18
ToppCell10x5'-GI_large-bowel-Lymphocytic_B_plasma|GI_large-bowel / Manually curated celltypes from each tissue

IGHV4-59 CERCAM IGHV4-28

9.94e-05185223989583c487d8c121e3731faf68f863ba43a582e6
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Immune-Lymphocytic_B-Plasma_Cell-|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

IGHV4-61 IGHV4-59 IGHV4-28

9.94e-051852230fff2608f507e019ebb69c27e58fd5be3b049bef
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Immune-Lymphocytic_B-Plasma_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

IGHV4-61 IGHV4-59 IGHV4-28

9.94e-0518522379edc1eeb7b5b9123961ac3ecf398ee68d9dddb9
ToppCell5'-Parenchyma_lung-Immune_Lymphocytic-Lymphocytic_B-plasma_cell|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

IGHV4-61 IGHV4-59 IGHV4-28

9.94e-051852231704a12153a9b107bf03ecccd1a036cf61334d7a
ToppCell10x5'-Liver-Lymphocytic_B_plasma|Liver / Manually curated celltypes from each tissue

IGHV4-61 IGHV4-59 IGHV4-28

1.01e-04186223a2c7430781f432c9c90ac4d620f4518ff767a223
ToppCellhealthy_donor-Lymphocytic-Plasma_cell-IgA_Plasmablast|healthy_donor / Disease condition, Lineage, Cell class and subclass

IGHV4-61 IGHV4-59 MANEA

1.01e-04186223e2c050ba02e1f84f0b7258dc92e7ff6ab349ff67
ToppCell3'_v3-lymph-node_spleen-Lymphocytic_B_plasma-Plasma_cells|lymph-node_spleen / Manually curated celltypes from each tissue

IGHV4-59 CERCAM MANEA

1.04e-04188223c7b1807c96f87fbcd37739a159cf00f9a1ff5d71
ToppCellCOVID-19_Mild-Lymphoid_P|COVID-19_Mild / Disease group, lineage and cell class

CRYBB1 IGHV4-59 MANEA

1.06e-041892230b3d3bd697e79decae7e21c513fab9da3b2a47c5
ToppCellPBMC-Mild-Lymphocyte-B-Plasmablast-Plasmablast-|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

CRYBB1 IGHV4-59 MANEA

1.06e-04189223c296660061b46e3abae1e7cf29df20274e5a8add
ToppCellCOVID-19_Mild-Lymphoid_P-Plasmablast|COVID-19_Mild / Disease group, lineage and cell class

CRYBB1 IGHV4-59 MANEA

1.06e-04189223254f058850b41a5974a380f3710db7c01a51fb6b
ToppCellPBMC-Mild-Lymphocyte-B-Plasmablast-Plasmablast-Plasmablast|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

IGHV4-59 MANEA IGHV4-28

1.06e-04189223a1bda6ed5c52a5d33d229018cb5982cae6305533
ToppCellPBMC-Mild-Lymphocyte-B-Plasmablast-Plasmablast|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

CRYBB1 IGHV4-59 MANEA

1.06e-0418922331594cc59eb1c5b01407dfd72b1487ecca8bf5ec
ToppCellPBMC-Mild-Lymphocyte-B-Plasmablast|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)

CRYBB1 IGHV4-59 MANEA

1.06e-041892239de17ade3cc3e9cd1394338bd048fb1ce64ac50f
ToppCellSmart-seq2-lymph_node_(Smart-seq2)-lymphocytic-B_lymphocytic-plasma_cell|lymph_node_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

IGHV4-61 IGHV4-59 IGHV4-28

1.08e-0419022376b747bafff09bf8375a5717c9f213cbfb405bac
ToppCell5'-Adult-LargeIntestine-Hematopoietic|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

IGHV4-61 IGHV4-59 IGHV4-28

1.09e-04191223d1d30279ed4612b4f62c225d9eabf0b8a7a09d11
ToppCellfacs-Aorta-Heart-3m-Mesenchymal-fibroblast|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC6A4 CERCAM DPT

1.09e-041912239214655dca96d766737c9f30b624d7fe7050342e
ToppCellTracheal-10x5prime-Immune_Lymphocytic-B-B_plasma|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

IGHV4-61 IGHV4-59 IGHV4-28

1.13e-04193223282b47dae6043eabb1e13d41d91c07b5ec21cd65
ToppCellParenchymal-10x5prime-Immune_Lymphocytic-B-B_plasma|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

IGHV4-61 IGHV4-59 IGHV4-28

1.14e-041942236ef4aeb8d8e35e4df58ff2a8256caa2113291de9
ToppCelldroplet-Lung-21m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l49|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

PKDREJ CERCAM DPT

1.14e-041942237826fe5eb254ac032de0d978f39585a40e0b3ee4
ToppCellTracheal-10x5prime-Immune_Lymphocytic-B-B_plasma-B_plasma_IgG|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

IGHV4-61 IGHV4-59 IGHV4-28

1.14e-04194223a4a70369541876e1192df8828b63e3d1746ae3d9
ToppCellBronchial-10x5prime-Immune_Lymphocytic-B-B_plasma-B_plasma_IgA|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

IGHV4-61 IGHV4-59 IGHV4-28

1.16e-0419522313f4ee21568fd747608412d33559d10561dbb3c8
ToppCellParenchymal-10x5prime-Immune_Lymphocytic-B-B_plasma-B_plasma_IgG|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

IGHV4-61 IGHV4-59 IGHV4-28

1.16e-04195223f3f7f1a77a1edd2b50a8211c76fe289738eb04cf
ToppCellTracheal-10x5prime-Immune_Lymphocytic-B-B_plasma-B_plasma_IgA|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

IGHV4-61 IGHV4-59 IGHV4-28

1.16e-04195223df009b18898c10686f75cf72b4ec0eff18f5bb50
ToppCellBronchial-10x5prime-Immune_Lymphocytic-B-B_plasma|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

IGHV4-61 IGHV4-59 IGHV4-28

1.18e-04196223c38e7f533c619afe008de0e99042f7180c2da918
ToppCellBiopsy_IPF-Immune-Plasma_cells|Biopsy_IPF / Sample group, Lineage and Cell type

IGHV4-61 IGHV4-59 IGHV4-28

1.18e-04196223a1b6a8000b86efcb07843998aa3a49bb1f54bcda
ToppCellBronchial-10x5prime-Immune_Lymphocytic-B-B_plasma-B_plasma_IgG|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

IGHV4-61 IGHV4-59 IGHV4-28

1.18e-04196223fec21383435779bf4c632decd3d29c6ca7baebfb
ToppCellBronchial-10x5prime-Immune_Lymphocytic-B|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

IGHV4-61 IGHV4-59 IGHV4-28

1.20e-0419722388b29d205237f07a9a26cc15a1cf4ed4816a4c4b
ToppCellTracheal-10x5prime-Immune_Lymphocytic-B|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

IGHV4-61 IGHV4-59 IGHV4-28

1.20e-041972232662138671262b30508c5759038bcdcfe6551696
ToppCellParenchymal-10x5prime-Immune_Lymphocytic-B-B_cell|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

IGHV4-61 IGHV4-59 IGHV4-28

1.20e-0419722376465bb2408c7c75f694e8f7cf1a606b796afc3a
ComputationalPeptide and AA transporters.

SLC16A4 SLC6A4

9.47e-051892MODULE_368
ComputationalGenes in the cancer module 162.

SLC16A4 SLC6A4

1.06e-041992MODULE_162
ComputationalGenes in the cancer module 218.

SLC16A4 SLC6A4

1.17e-042092MODULE_218
DrugDBTC

HYAL4 CRYBA1 CRYBB1

2.95e-0573193CID000101938
Drug5-MeO-DIPT

SLC6A4 DPT

5.97e-0514192CID000151182
DrugCH3SOH

CRYBA1 CRYBB1

6.88e-0515192CID000123554
DrugMBDB

SLC6A4 DPT

8.91e-0517192CID000124844
DrugHY-1

CRYBA1 CRYBB1

1.00e-0418192CID000192888
Drugheptamolybdate

CRYBA1 SLC6A4 CRYBB1

1.06e-04112193CID005288823
Drugviridine

CRYBA1 CRYBB1

2.46e-0428192CID000060995
Drugbutylphenyl

SLC6A4 PRIM1

3.02e-0431192CID000143181
DrugHis-pro-dkp

SLC6A5 SLC6A4

3.02e-0431192CID000065137
Drugkhellin

CRYBA1 CRYBB1 DPT

3.69e-04171193CID000003828
Drugatomoxetine

SLC6A4 DNASE2

4.09e-0436192CID000054840
Drugsipatrigine

SLC6A5 SLC6A4

4.32e-0437192CID000060803
Drugerythrose

CRYBA1 CRYBB1

5.05e-0440192CID000094176
Drugdoxepin

SLC6A5 SLC6A4

5.05e-0440192CID000003158
DrugCiguatoxins

SLC16A4 SUN2 DNASE2 PRIM1 CPM

5.24e-04845195ctd:D002922
Drugdesvenlafaxine

SLC6A5 SLC6A4

5.31e-0441192CID000125017
DrugTrimipramine maleate salt [521-78-8]; Up 200; 9.8uM; PC3; HT_HG-U133A

NTNG1 DPT SIGLEC6

5.34e-041941934083_UP
DrugFurazolidone [67-45-8]; Up 200; 17.8uM; PC3; HT_HG-U133A

SLC16A4 NTNG1 DPT

5.42e-041951934098_UP
DrugClemizole hydrochloride [1163-36-6]; Up 200; 11uM; HL60; HT_HG-U133A

DNASE2 SIGLEC6 CPM

5.50e-041961932339_UP
DrugAmikacin hydrate [37517-28-5]; Up 200; 6.6uM; PC3; HT_HG-U133A

NTNG1 SIGLEC6 CPM

5.50e-041961936715_UP
DrugRoxithromycin [80214-83-1]; Down 200; 4.8uM; HL60; HT_HG-U133A

SLC16A4 SIGLEC6 CPM

5.58e-041971932992_DN
DrugRaloxifene hydrochloride [82640-04-8]; Down 200; 7.8uM; HL60; HT_HG-U133A

DNASE2 SIGLEC6 CPM

5.58e-041971932738_DN
DrugHecogenin [467-55-0]; Up 200; 9.2uM; HL60; HT_HG-U133A

HYAL4 SLC6A4 DNASE2

5.66e-041981932716_UP
DrugDimaprit dihydrochloride [23256-33-9]; Up 200; 17uM; MCF7; HT_HG-U133A

HYAL4 DPT SIGLEC6

5.66e-041981936520_UP
DrugTolmetin sodium salt dihydrate [64490-92-2]; Up 200; 12.6uM; HL60; HT_HG-U133A

SLC16A4 CRYBB1 DPT

5.66e-041981933009_UP
DrugScopolamine hydrochloride [55-16-3]; Up 200; 11.8uM; PC3; HT_HG-U133A

SLC16A4 CRYBB1 DPT

5.75e-041991934219_UP
Drughaloperidol; Up 200; 10uM; HL60; HT_HG-U133A

SLC16A4 NTNG1 DNASE2

5.75e-041991931185_UP
DrugLuteolin [491-70-3]; Up 200; 14uM; PC3; HT_HG-U133A

SLC16A4 NTNG1 SIGLEC6

5.75e-041991936658_UP
Drugalpha-estradiol; Down 200; 0.01uM; HL60; HT_HG-U133A

SLC16A4 DNASE2 SIGLEC6

5.83e-042001932670_DN
Drugamoxapine

SLC6A5 SLC6A4

6.68e-0446192CID000002170
Drugnomifensine

SLC6A5 SLC6A4

6.68e-0446192CID000004528
Drug2-(2-naphthyloxy)propanoic acid

SLC6A5 DPT

6.97e-0447192CID000092236
DrugV ms

SLC6A4 BIRC6

7.58e-0449192CID005289556
DrugT1 p

CRYBA1 CRYBB1

8.21e-0451192CID000657023
Drugmepivacaine

HYAL4 SLC6A4

8.21e-0451192CID000004062
DrugMtT-S

CRYBA1 CRYBB1

8.21e-0451192CID000131613
DrugN-nitrosomorpholine

DPT DNASE2

8.53e-0452192CID000006046
DrugNSC190421

DPT DNASE2

8.86e-0453192CID000002545
DiseaseNuclear cataract

CRYBA1 CRYBB1

5.97e-0518192C0392557
DiseaseNuclear non-senile cataract

CRYBA1 CRYBB1

5.97e-0518192C1112705
Diseasecataract (is_implicated_in)

CRYBA1 CRYBB1

1.26e-0426192DOID:83 (is_implicated_in)
Diseaseunipolar depression

CRYBA1 SLC6A4 DPT MANEA CPM

8.14e-041206195EFO_0003761
DiseaseLupus Erythematosus, Systemic

DNASE2 SIGLEC6

9.51e-0471192C0024141
DiseaseManic Disorder

SLC6A4 NTNG1

9.51e-0471192C0024713
DiseaseManic

SLC6A4 NTNG1

1.15e-0378192C0338831
DiseaseDepression, Bipolar

SLC6A4 NTNG1

1.18e-0379192C0005587
Diseaseaspartate aminotransferase measurement, serum alanine aminotransferase measurement, low density lipoprotein triglyceride measurement, body fat percentage, high density lipoprotein cholesterol measurement, sex hormone-binding globulin measurement

SLC6A4 NTNG1 SSH2

1.56e-03364193EFO_0004612, EFO_0004696, EFO_0004735, EFO_0004736, EFO_0007800, EFO_0009946
Diseasewhite matter microstructure measurement

JPH1 SUN2 SSH2

1.90e-03390193EFO_0005674
DiseaseCocaine-Related Disorders

SLC6A4 MANEA

2.55e-03117192C0236736
DiseaseCocaine Abuse

SLC6A4 MANEA

3.00e-03127192C0009171
DiseaseCocaine Dependence

SLC6A4 MANEA

3.57e-03139192C0600427
Diseasebody fat percentage

SLC6A4 NTNG1 SSH2

3.58e-03488193EFO_0007800

Protein segments in the cluster

PeptideGeneStartEntry
YDYWGADYGTYNYNP

BIRC6

2521

Q9NR09
GTWVGYQYPGYRGYQ

CRYBB1

191

P53674
AWGQYGDYGYPYQQY

DPT

16

Q07507
GYTWPSGNTYQGYWA

JPH1

51

Q9HDC5
LEWIGYIYYSGSTNY

IGHV4-61

66

A0A0C4DH41
EWIGYIYYSGSTYYN

IGHV4-28

66

A0A0C4DH34
WIGYIYYSGSTNYNP

IGHV4-59

66

P01825
NYLHVFYYSWYGNPQ

MANEA

101

Q5SRI9
FPYSQYYRWLNYGGV

PRIM1

21

P49642
GKQLTYTYPWVYNYQ

DNASE2

171

O00115
YSWYPLQGGMQDYNY

CPM

256

P14384
GAWVCYQYPGYRGYQ

CRYBA1

166

P05813
YVNRLGYYPWYTSQG

HYAL4

91

Q2M3T9
YYSNFWCGITPQGYY

CERCAM

176

Q5T4B2
LDYGRTWQPYQYYAT

NTNG1

166

Q9Y2I2
SFYQWEPMTYGSYRY

SLC6A5

696

Q9Y345
FTYKPQGTQWLYYSY

PKDREJ

1856

Q9NTG1
TLPASYYGYGYWFLE

SIGLEC6

56

O43699
GWLYDYTQTYNGSFY

SLC16A4

446

O15374
LTYGAWYFYPYGLQT

SUN2

226

Q9UH99
YYPGSLFLTWVSYYE

SSH2

196

Q76I76
FQYNYPYWSIILGYC

SLC6A4

566

P31645