Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	histone H3K4 monomethyltransferase activity	SETD1A KMT2C SETD1B	1.91e-06	8	66	3	GO:0140945
GeneOntologyMolecularFunction	histone H3K4 trimethyltransferase activity	SETD1A KMT2C SETD1B	4.07e-06	10	66	3	GO:0140999
GeneOntologyMolecularFunction	protein kinase activity	TRIO GUCY2F CDK13 TBCK OBSCN MAST1 FGFR1 WNK1 PTK2 MAP3K2	2.58e-05	600	66	10	GO:0004672
GeneOntologyMolecularFunction	histone H3K4 methyltransferase activity	SETD1A KMT2C SETD1B	3.78e-05	20	66	3	GO:0042800
GeneOntologyMolecularFunction	phosphotransferase activity, alcohol group as acceptor	TRIO GUCY2F CDK13 TBCK OBSCN MAST1 FGFR1 WNK1 PTK2 MAP3K2	1.05e-04	709	66	10	GO:0016773
GeneOntologyMolecularFunction	kinase activity	TRIO GUCY2F CDK13 TBCK OBSCN MAST1 FGFR1 WNK1 PTK2 MAP3K2	1.92e-04	764	66	10	GO:0016301
GeneOntologyMolecularFunction	histone H3 methyltransferase activity	SETD1A KMT2C SETD1B	4.15e-04	44	66	3	GO:0140938
GeneOntologyMolecularFunction	phosphatidylinositol-3,4,5-trisphosphate binding	FCHSD2 OBSCN ARAP2	5.70e-04	49	66	3	GO:0005547
GeneOntologyMolecularFunction	cytoskeletal protein binding	FAM161A PPP1R9A OBSCN DIAPH1 MAST1 KIF14 TOGARAM1 CEP295 EMD SHROOM2 PTK2	8.83e-04	1099	66	11	GO:0008092
GeneOntologyMolecularFunction	transferase activity, transferring phosphorus-containing groups	TRIO GUCY2F CDK13 TBCK OBSCN MAST1 FGFR1 WNK1 PTK2 MAP3K2	9.63e-04	938	66	10	GO:0016772
GeneOntologyMolecularFunction	protein serine kinase activity	TRIO CDK13 OBSCN MAST1 WNK1 MAP3K2	1.26e-03	363	66	6	GO:0106310
GeneOntologyMolecularFunction	protein-lysine N-methyltransferase activity	SETD1A KMT2C SETD1B	1.48e-03	68	66	3	GO:0016279
GeneOntologyMolecularFunction	lysine N-methyltransferase activity	SETD1A KMT2C SETD1B	1.55e-03	69	66	3	GO:0016278
GeneOntologyMolecularFunction	histone methyltransferase activity	SETD1A KMT2C SETD1B	1.68e-03	71	66	3	GO:0042054
GeneOntologyMolecularFunction	protein kinase binding	CDK13 PPP1R9A KIF14 ZFYVE26 LRRC7 WNK1 PTK2 FAM83A MAP3K2	2.21e-03	873	66	9	GO:0019901
GeneOntologyMolecularFunction	S-adenosylmethionine-dependent methyltransferase activity	SETD1A KMT2C SETD1B MEPCE	2.53e-03	172	66	4	GO:0008757
GeneOntologyMolecularFunction	tubulin binding	FAM161A MAST1 KIF14 TOGARAM1 CEP295 EMD	2.88e-03	428	66	6	GO:0015631
GeneOntologyMolecularFunction	microtubule binding	FAM161A MAST1 KIF14 TOGARAM1 CEP295	3.50e-03	308	66	5	GO:0008017
GeneOntologyMolecularFunction	protein serine/threonine kinase activity	TRIO CDK13 OBSCN MAST1 WNK1 MAP3K2	3.52e-03	446	66	6	GO:0004674
GeneOntologyMolecularFunction	phosphatidylinositol phosphate binding	FCHSD2 OBSCN ZFYVE26 ARAP2	4.26e-03	199	66	4	GO:1901981
GeneOntologyMolecularFunction	kinase binding	CDK13 PPP1R9A KIF14 ZFYVE26 LRRC7 WNK1 PTK2 FAM83A MAP3K2	4.43e-03	969	66	9	GO:0019900
GeneOntologyMolecularFunction	protein methyltransferase activity	SETD1A KMT2C SETD1B	4.82e-03	103	66	3	GO:0008276
GeneOntologyMolecularFunction	N-methyltransferase activity	SETD1A KMT2C SETD1B	5.09e-03	105	66	3	GO:0008170
GeneOntologyMolecularFunction	methyltransferase activity	SETD1A KMT2C SETD1B MEPCE	5.41e-03	213	66	4	GO:0008168
GeneOntologyMolecularFunction	phosphatidylinositol-3,4-bisphosphate binding	FCHSD2 OBSCN	5.97e-03	35	66	2	GO:0043325
GeneOntologyBiologicalProcess	cerebral cortex GABAergic interneuron fate commitment	DLX1 DLX2	9.78e-06	2	65	2	GO:0021893
GeneOntologyCellularComponent	Set1C/COMPASS complex	SETD1A SETD1B HCFC2	1.71e-05	16	67	3	GO:0048188
GeneOntologyCellularComponent	histone methyltransferase complex	SETD1A KMT2C SETD1B HCFC2	9.87e-05	75	67	4	GO:0035097
GeneOntologyCellularComponent	methyltransferase complex	SETD1A KMT2C SETD1B HCFC2	4.02e-04	108	67	4	GO:0034708
GeneOntologyCellularComponent	mitotic spindle	FAM161A TBCK DIAPH1 CEP295 WNK1	4.66e-04	201	67	5	GO:0072686
GeneOntologyCellularComponent	spindle	FAM161A TBCK DIAPH1 KIF14 CEP295 EMD WNK1	7.64e-04	471	67	7	GO:0005819
MousePheno	small stapes	DLX1 DLX2 FGFR1	8.67e-07	5	63	3	MP:0030127
MousePheno	small middle ear ossicles	DLX1 DLX2 FGFR1	5.67e-05	17	63	3	MP:0030123
MousePheno	absent stapes obturator foramen	DLX1 DLX2	5.98e-05	3	63	2	MP:0030406
Domain	Prot_kinase_dom	TRIO GUCY2F CDK13 TBCK OBSCN MAST1 FGFR1 WNK1 PTK2 MAP3K2	7.83e-06	489	66	10	IPR000719
Domain	PROTEIN_KINASE_DOM	TRIO GUCY2F CDK13 TBCK OBSCN MAST1 FGFR1 WNK1 PTK2 MAP3K2	8.41e-06	493	66	10	PS50011
Domain	N-SET	SETD1A SETD1B	1.23e-05	2	66	2	PF11764
Domain	COMPASS_Set1_N-SET	SETD1A SETD1B	1.23e-05	2	66	2	IPR024657
Domain	N-SET	SETD1A SETD1B	1.23e-05	2	66	2	SM01291
Domain	Kinase-like_dom	TRIO GUCY2F CDK13 TBCK OBSCN MAST1 FGFR1 WNK1 PTK2 MAP3K2	1.91e-05	542	66	10	IPR011009
Domain	Post-SET_dom	SETD1A KMT2C SETD1B	2.28e-05	16	66	3	IPR003616
Domain	PostSET	SETD1A KMT2C SETD1B	2.28e-05	16	66	3	SM00508
Domain	POST_SET	SETD1A KMT2C SETD1B	2.28e-05	16	66	3	PS50868
Domain	Pkinase	TRIO GUCY2F CDK13 TBCK OBSCN MAST1 WNK1 MAP3K2	5.70e-05	381	66	8	PF00069
Domain	PROTEIN_KINASE_ATP	TRIO CDK13 OBSCN MAST1 FGFR1 WNK1 PTK2 MAP3K2	2.06e-04	459	66	8	PS00107
Domain	SET	SETD1A KMT2C SETD1B	4.08e-04	41	66	3	PF00856
Domain	SET	SETD1A KMT2C SETD1B	5.74e-04	46	66	3	SM00317
Domain	SET_dom	SETD1A KMT2C SETD1B	7.34e-04	50	66	3	IPR001214
Domain	SET	SETD1A KMT2C SETD1B	7.34e-04	50	66	3	PS50280
Domain	DH_1	TRIO OBSCN PLEKHG5	1.44e-03	63	66	3	PS00741
Domain	PDZ	PPP1R9A MAST1 LRRC7 SHROOM2	1.56e-03	141	66	4	PF00595
Domain	Ser/Thr_kinase_AS	TRIO CDK13 OBSCN MAST1 WNK1 MAP3K2	1.62e-03	357	66	6	IPR008271
Domain	S_TKc	TRIO CDK13 OBSCN MAST1 WNK1 MAP3K2	1.67e-03	359	66	6	SM00220
Domain	PROTEIN_KINASE_ST	TRIO CDK13 OBSCN MAST1 WNK1 MAP3K2	1.74e-03	362	66	6	PS00108
Domain	RhoGEF	TRIO OBSCN PLEKHG5	1.79e-03	68	66	3	SM00325
Domain	PDZ	PPP1R9A MAST1 LRRC7 SHROOM2	1.86e-03	148	66	4	SM00228
Domain	RhoGEF	TRIO OBSCN PLEKHG5	1.95e-03	70	66	3	PF00621
Domain	DH_2	TRIO OBSCN PLEKHG5	1.95e-03	70	66	3	PS50010
Domain	-	PPP1R9A MAST1 LRRC7 SHROOM2	1.96e-03	150	66	4	2.30.42.10
Domain	PDZ	PPP1R9A MAST1 LRRC7 SHROOM2	2.01e-03	151	66	4	PS50106
Domain	DH-domain	TRIO OBSCN PLEKHG5	2.03e-03	71	66	3	IPR000219
Domain	-	TRIO OBSCN PLEKHG5	2.03e-03	71	66	3	1.20.900.10
Domain	PDZ	PPP1R9A MAST1 LRRC7 SHROOM2	2.05e-03	152	66	4	IPR001478
Domain	SAM	PPP1R9A SEC23IP ARAP2	3.73e-03	88	66	3	SM00454
Domain	Ig_I-set	NEO1 TRIO OBSCN FGFR1	4.58e-03	190	66	4	IPR013098
Domain	I-set	NEO1 TRIO OBSCN FGFR1	4.58e-03	190	66	4	PF07679
Domain	SAM_DOMAIN	PPP1R9A SEC23IP ARAP2	4.63e-03	95	66	3	PS50105
Domain	PROTEIN_KINASE_TYR	OBSCN FGFR1 PTK2	4.90e-03	97	66	3	PS00109
Domain	SAM	PPP1R9A SEC23IP ARAP2	4.90e-03	97	66	3	IPR001660
Domain	Tyr_kinase_AS	OBSCN FGFR1 PTK2	4.90e-03	97	66	3	IPR008266
Domain	-	PPP1R9A SEC23IP ARAP2	6.27e-03	106	66	3	1.10.150.50
Domain	SAM/pointed	PPP1R9A SEC23IP ARAP2	8.23e-03	117	66	3	IPR013761
Domain	GDS_CDC24_CS	TRIO OBSCN	8.38e-03	39	66	2	IPR001331
Domain	IGc2	NEO1 TRIO OBSCN FGFR1	9.58e-03	235	66	4	SM00408
Domain	Ig_sub2	NEO1 TRIO OBSCN FGFR1	9.58e-03	235	66	4	IPR003598
Pathway	REACTOME_FORMATION_OF_WDR5_CONTAINING_HISTONE_MODIFYING_COMPLEXES	SETD1A KMT2C SETD1B HCFC2	1.31e-05	42	49	4	M48018
Pathway	REACTOME_RHOA_GTPASE_CYCLE	TRIO OBSCN DIAPH1 PLEKHG5 ARAP2	1.29e-04	142	49	5	MM15576
Pathway	REACTOME_RHOA_GTPASE_CYCLE	TRIO OBSCN DIAPH1 PLEKHG5 ARAP2	1.62e-04	149	49	5	M41805
Pathway	REACTOME_FORMATION_OF_WDR5_CONTAINING_HISTONE_MODIFYING_COMPLEXES	SETD1A SETD1B HCFC2	3.06e-04	38	49	3	MM17073
Pathway	REACTOME_DCC_MEDIATED_ATTRACTIVE_SIGNALING	TRIO PTK2	4.20e-04	9	49	2	MM15059
Pathway	REACTOME_NETRIN_1_SIGNALING	NEO1 TRIO PTK2	4.73e-04	44	49	3	M875
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	FCHSD2 SETD1B ZBED4 PRRC2C PPP1R9A MAST1 LRRC7 CAMTA2 SRRM2 FAIM2 ARAP2	3.52e-10	407	67	11	12693553
Pubmed	Structural basis for activity regulation of MLL family methyltransferases.	SETD1A KMT2C SETD1B HCFC2	8.96e-08	22	67	4	26886794
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	SETD1A KMT2C SETD1B ZBED4 TRIO CDK13 OBSCN ZFYVE26 DLX2 FGFR1 WNK1 PLEKHG5 MYRF	1.62e-07	1105	67	13	35748872
Pubmed	Skirting the pitfalls: a clear-cut nomenclature for H3K4 methyltransferases.	SETD1A KMT2C SETD1B	3.80e-07	8	67	3	23130995
Pubmed	The plasticity of WDR5 peptide-binding cleft enables the binding of the SET1 family of histone methyltransferases.	SETD1A KMT2C SETD1B	3.80e-07	8	67	3	22266653
Pubmed	Structural basis for WDR5 interaction (Win) motif recognition in human SET1 family histone methyltransferases.	SETD1A KMT2C SETD1B	5.69e-07	9	67	3	22665483
Pubmed	Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.	KMT2C FAM120A ZNF608 TRIO CDK13 PPP1R9A TBCK OBSCN AUTS2 MAST1 LRRC7 SHROOM2 SSPOP PTK2	7.61e-07	1489	67	14	28611215
Pubmed	An antibody-based proximity labeling map reveals mechanisms of SARS-CoV-2 inhibition of antiviral immunity.	NEO1 FAM120A TRIO YLPM1 SEC23IP DIAPH1 KIF14 CEP295 WNK1 LYSMD3	1.37e-06	733	67	10	34672954
Pubmed	Targeted Disruption of the Interaction between WD-40 Repeat Protein 5 (WDR5) and Mixed Lineage Leukemia (MLL)/SET1 Family Proteins Specifically Inhibits MLL1 and SETd1A Methyltransferase Complexes.	SETD1A KMT2C SETD1B	1.48e-06	12	67	3	27563068
Pubmed	Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.	FAM120A TRIO PRRC2C PPP1R9A YLPM1 SEC23IP ZBTB22 DIAPH1 LRRC7 PTK2 BEGAIN	2.16e-06	963	67	11	28671696
Pubmed	CNTF/LIF/gp130 receptor complex signaling maintains a VZ precursor differentiation gradient in the developing ventral forebrain.	DLX1 DLX2 FGFR1	2.45e-06	14	67	3	15634701
Pubmed	Epigenetic-focused CRISPR/Cas9 screen identifies (absent, small, or homeotic)2-like protein (ASH2L) as a regulator of glioblastoma cell survival.	SETD1A KMT2C SETD1B HCFC2	2.71e-06	50	67	4	37974198
Pubmed	In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.	GPALPP1 KHDRBS3 ZBED4 ZNF608 CDK13 FAM161A PRRC2C PPP1R9A YLPM1 SEC23IP CEP295 FGFR1 FBXO15	3.19e-06	1442	67	13	35575683
Pubmed	Sequence, organization, and transcription of the Dlx-1 and Dlx-2 locus.	DLX1 DLX2	3.66e-06	2	67	2	8812481
Pubmed	The DLX1and DLX2 genes and susceptibility to autism spectrum disorders.	DLX1 DLX2	3.66e-06	2	67	2	18728693
Pubmed	The Rho guanine nucleotide exchange factor Syx regulates the balance of dia and ROCK activities to promote polarized-cancer-cell migration.	DIAPH1 PLEKHG5	3.66e-06	2	67	2	24126053
Pubmed	The H3K4 methyltransferase Setd1a is first required at the epiblast stage, whereas Setd1b becomes essential after gastrulation.	SETD1A SETD1B	3.66e-06	2	67	2	24550110
Pubmed	In Vivo and In Vitro Characterization of the RNA Binding Capacity of SETD1A (KMT2F).	SETD1A SETD1B	3.66e-06	2	67	2	38003223
Pubmed	Distinct cis-regulatory elements from the Dlx1/Dlx2 locus mark different progenitor cell populations in the ganglionic eminences and different subtypes of adult cortical interneurons.	DLX1 DLX2	3.66e-06	2	67	2	17494687
Pubmed	Signaling between focal adhesion kinase and trio.	TRIO PTK2	3.66e-06	2	67	2	12551902
Pubmed	Dlx-1 and Dlx-2 expression in the adult mouse brain: relationship to dopaminergic phenotypic regulation.	DLX1 DLX2	3.66e-06	2	67	2	12722102
Pubmed	Interneuron migration from basal forebrain to neocortex: dependence on Dlx genes.	DLX1 DLX2	3.66e-06	2	67	2	9334308
Pubmed	SET1 and p300 act synergistically, through coupled histone modifications, in transcriptional activation by p53.	SETD1A KMT2C SETD1B	3.76e-06	16	67	3	23870121
Pubmed	H3K4 mono- and di-methyltransferase MLL4 is required for enhancer activation during cell differentiation.	SETD1A KMT2C SETD1B	3.76e-06	16	67	3	24368734
Pubmed	Dlx-dependent and -independent regulation of olfactory bulb interneuron differentiation.	SP9 DLX1 DLX2	4.56e-06	17	67	3	17376983
Pubmed	SMYD3 Impedes Small Cell Lung Cancer Sensitivity to Alkylation Damage through RNF113A Methylation-Phosphorylation Cross-talk.	FAM120A CDK13 PRRC2C YLPM1 MEPCE DIAPH1 EMD SRRM2 MAP3K2	4.56e-06	655	67	9	35819319
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	VPS13D TRIO PRRC2C MEPCE KIF14 CRTC1 SRRM2 WNK1 ARAP2 MAP3K2	5.69e-06	861	67	10	36931259
Pubmed	A lentiviral functional proteomics approach identifies chromatin remodeling complexes important for the induction of pluripotency.	SETD1A KMT2C SETD1B HCFC2	6.04e-06	61	67	4	20305087
Pubmed	SR protein kinases promote splicing of nonconsensus introns.	ABCA13 CDK13 PRRC2C KIF14 TOGARAM1 CRTC1 SRRM2	6.24e-06	361	67	7	26167880
Pubmed	Resetting the epigenetic balance of Polycomb and COMPASS function at enhancers for cancer therapy.	SETD1A KMT2C SETD1B	7.61e-06	20	67	3	29785026
Pubmed	SETD1A Methyltransferase Is Physically and Functionally Linked to the DNA Damage Repair Protein RAD18.	SETD1A KMT2C SETD1B FAM120A PRRC2C HCFC2	9.19e-06	251	67	6	31076518
Pubmed	Long-term potentiation modulates synaptic phosphorylation networks and reshapes the structure of the postsynaptic interactome.	TRIO PPP1R9A DIAPH1 LRRC7 PTK2 BEGAIN	9.19e-06	251	67	6	27507650
Pubmed	Fgfr1 regulates patterning of the pharyngeal region.	DLX1 DLX2 FGFR1	1.03e-05	22	67	3	12514106
Pubmed	WDR82, a key epigenetics-related factor, plays a crucial role in normal early embryonic development in mice.	SETD1A SETD1B	1.10e-05	3	67	2	21123813
Pubmed	Identification of a direct Dlx homeodomain target in the developing mouse forebrain and retina by optimization of chromatin immunoprecipitation.	DLX1 DLX2	1.10e-05	3	67	2	14769946
Pubmed	Molecular insight into the SETD1A/B N-terminal region and its interaction with WDR82.	SETD1A SETD1B	1.10e-05	3	67	2	37030068
Pubmed	Generation of Cre-transgenic mice using Dlx1/Dlx2 enhancers and their characterization in GABAergic interneurons.	DLX1 DLX2	1.10e-05	3	67	2	19026749
Pubmed	Integrative analysis of the cancer genome atlas and cancer cell lines encyclopedia large-scale genomic databases: MUC4/MUC16/MUC20 signature is associated with poor survival in human carcinomas.	MUC16 MUC20	1.10e-05	3	67	2	30236127
Pubmed	WNK1 activates ERK5 by an MEKK2/3-dependent mechanism.	WNK1 MAP3K2	1.10e-05	3	67	2	14681216
Pubmed	The proneural determinant MASH1 regulates forebrain Dlx1/2 expression through the I12b intergenic enhancer.	DLX1 DLX2	1.10e-05	3	67	2	17409112
Pubmed	Distal-less homeobox transcription factors regulate development and maturation of natural killer cells.	DLX1 DLX2	1.10e-05	3	67	2	18664585
Pubmed	Differential Expression of MUC12, MUC16, and MUC20 in Patients with Active and Remission Ulcerative Colitis.	MUC16 MUC20	1.10e-05	3	67	2	26770020
Pubmed	The organization of the transcriptional network in specific neuronal classes.	DLX1 DLX2	1.10e-05	3	67	2	19638972
Pubmed	Polymorphisms in genes involved in enamel development are associated with dental fluorosis.	DLX1 DLX2	1.10e-05	3	67	2	28131910
Pubmed	Origins of cortical interneuron subtypes.	DLX1 DLX2	1.10e-05	3	67	2	15028753
Pubmed	Up-regulation of homeodomain genes, DLX1 and DLX2, by FLT3 signaling.	DLX1 DLX2	1.10e-05	3	67	2	21357706
Pubmed	The glucocorticoid receptor recruits the COMPASS complex to regulate inflammatory transcription at macrophage enhancers.	SETD1A SETD1B	1.10e-05	3	67	2	33567280
Pubmed	Serotonin 3A receptor subtype as an early and protracted marker of cortical interneuron subpopulations.	DLX1 DLX2	1.10e-05	3	67	2	20083553
Pubmed	Arx is a direct target of Dlx2 and thereby contributes to the tangential migration of GABAergic interneurons.	DLX1 DLX2	1.10e-05	3	67	2	18923043
Pubmed	Loss of Gsx1 and Gsx2 function rescues distinct phenotypes in Dlx1/2 mutants.	SP9 DLX1 DLX2	1.52e-05	25	67	3	23042297
Pubmed	Differential expression of paralog RNA binding proteins establishes a dynamic splicing program required for normal cerebral cortex development.	KHDRBS3 LRRC7 WNK1	2.16e-05	28	67	3	38324473
Pubmed	Dlx1/2 are Central and Essential Components in the Transcriptional Code for Generating Olfactory Bulb Interneurons.	SP9 DLX1 DLX2	2.16e-05	28	67	3	30796806
Pubmed	SP8 and SP9 coordinately promote D2-type medium spiny neuron production by activating Six3 expression.	SP9 DLX1 DLX2	2.16e-05	28	67	3	29967281
Pubmed	Focal adhesion kinase in netrin-1 signaling.	NEO1 PTK2	2.19e-05	4	67	2	15494733
Pubmed	Cloning and characterization of two members of the vertebrate Dlx gene family.	DLX1 DLX2	2.19e-05	4	67	2	7907794
Pubmed	GABAergic Interneuron Differentiation in the Basal Forebrain Is Mediated through Direct Regulation of Glutamic Acid Decarboxylase Isoforms by Dlx Homeobox Transcription Factors.	DLX1 DLX2	2.19e-05	4	67	2	28821666
Pubmed	A highly conserved enhancer in the Dlx5/Dlx6 intergenic region is the site of cross-regulatory interactions between Dlx genes in the embryonic forebrain.	DLX1 DLX2	2.19e-05	4	67	2	10632600
Pubmed	Dlx genes encode DNA-binding proteins that are expressed in an overlapping and sequential pattern during basal ganglia differentiation.	DLX1 DLX2	2.19e-05	4	67	2	9415433
Pubmed	DLX-1, DLX-2, and DLX-5 expression define distinct stages of basal forebrain differentiation.	DLX1 DLX2	2.19e-05	4	67	2	10516593
Pubmed	Dlx1 and Dlx2 Promote Interneuron GABA Synthesis, Synaptogenesis, and Dendritogenesis.	DLX1 DLX2	2.19e-05	4	67	2	29028947
Pubmed	Zfhx3 is required for the differentiation of late born D1-type medium spiny neurons.	SP9 DLX1 DLX2	2.41e-05	29	67	3	31491374
Pubmed	Comparative Application of BioID and TurboID for Protein-Proximity Biotinylation.	KMT2C PRRC2C YLPM1 SEC23IP GLIS3 AUTS2 EMD	2.85e-05	457	67	7	32344865
Pubmed	Identification and characterization of a novel human PP1 phosphatase complex.	SETD1A KMT2C SETD1B	2.96e-05	31	67	3	20516061
Pubmed	Dlx1/2-dependent expression of Meis2 promotes neuronal fate determination in the mammalian striatum.	SP9 DLX1 DLX2	3.26e-05	32	67	3	35156680
Pubmed	Spatially restricted expression of Dlx-1, Dlx-2 (Tes-1), Gbx-2, and Wnt-3 in the embryonic day 12.5 mouse forebrain defines potential transverse and longitudinal segmental boundaries.	DLX1 DLX2	3.64e-05	5	67	2	7687285
Pubmed	Biochemical reconstitution and phylogenetic comparison of human SET1 family core complexes involved in histone methylation.	SETD1A SETD1B	3.64e-05	5	67	2	25561738
Pubmed	RhoD activated by fibroblast growth factor induces cytoneme-like cellular protrusions through mDia3C.	DIAPH1 FGFR1	3.64e-05	5	67	2	23034183
Pubmed	Order of six loci at 2q24-q31 and orientation of the HOXD locus.	DLX1 DLX2	3.64e-05	5	67	2	7896287
Pubmed	Expression of the Rap1 guanine nucleotide exchange factor, MR-GEF, is altered in individuals with bipolar disorder.	DLX1 DLX2	3.64e-05	5	67	2	20436929
Pubmed	The evolution of the vertebrate Dlx gene family.	DLX1 DLX2	3.64e-05	5	67	2	8855272
Pubmed	Actin-capping protein promotes microtubule stability by antagonizing the actin activity of mDia1.	DIAPH1 PTK2	3.64e-05	5	67	2	22918941
Pubmed	FGFs and BMP4 induce both Msx1-independent and Msx1-dependent signaling pathways in early tooth development.	DLX1 DLX2	3.64e-05	5	67	2	9753686
Pubmed	The vertebrate ortholog of Aristaless is regulated by Dlx genes in the developing forebrain.	DLX1 DLX2	3.64e-05	5	67	2	15682394
Pubmed	Ectopic expression of the Dlx genes induces glutamic acid decarboxylase and Dlx expression.	DLX1 DLX2	3.64e-05	5	67	2	11782417
Pubmed	Role of the Dlx homeobox genes in proximodistal patterning of the branchial arches: mutations of Dlx-1, Dlx-2, and Dlx-1 and -2 alter morphogenesis of proximal skeletal and soft tissue structures derived from the first and second arches.	DLX1 DLX2	3.64e-05	5	67	2	9187081
Pubmed	Rewiring of RSK-PDZ Interactome by Linear Motif Phosphorylation.	PPP1R9A MAST1 SHROOM2	3.92e-05	34	67	3	30726710
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	GPALPP1 VPS13D FAM120A CDK13 TOGARAM1 MON1B WNK1	4.60e-05	493	67	7	15368895
Pubmed	Prediction of the coding sequences of unidentified human genes. VII. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro.	SETD1A ZFYVE26 SRRM2 WNK1	5.00e-05	104	67	4	9205841
Pubmed	Expression of Dlx genes during the development of the murine dentition.	DLX1 DLX2	5.46e-05	6	67	2	11180832
Pubmed	Brn-3b inhibits generation of amacrine cells by binding to and negatively regulating DLX1/2 in developing retina.	DLX1 DLX2	5.46e-05	6	67	2	21875655
Pubmed	Differential expression of orthologous Dlx genes in zebrafish and mice: implications for the evolution of the Dlx homeobox gene family.	DLX1 DLX2	5.46e-05	6	67	2	11069141
Pubmed	Variation of tooth number in mammalian dentition: connecting genetics, development, and evolution.	DLX1 DLX2	5.46e-05	6	67	2	12752768
Pubmed	Dlx homeobox genes promote cortical interneuron migration from the basal forebrain by direct repression of the semaphorin receptor neuropilin-2.	DLX1 DLX2	5.46e-05	6	67	2	17259176
Pubmed	Differential modulation of BMP signaling promotes the elaboration of cerebral cortical GABAergic neurons or oligodendrocytes from a common sonic hedgehog-responsive ventral forebrain progenitor species.	DLX1 DLX2	5.46e-05	6	67	2	12461181
Pubmed	Identification and characterization of a novel transcript down-regulated in Dlx1/Dlx2 and up-regulated in Pax6 mutant telencephalon.	DLX1 DLX2	5.46e-05	6	67	2	15376329
Pubmed	Evf2 (Dlx6as) lncRNA regulates ultraconserved enhancer methylation and the differential transcriptional control of adjacent genes.	DLX1 DLX2	5.46e-05	6	67	2	24089468
Pubmed	Developmental regulation of gonadotropin-releasing hormone gene expression by the MSX and DLX homeodomain protein families.	DLX1 DLX2	5.46e-05	6	67	2	15743757
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	SETD1A KMT2C ZNF608 AUTS2 CRTC1 FAIM2 PLEKHG5	7.16e-05	529	67	7	14621295
Pubmed	Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.	KMT2C ZNF608 AUTS2 TOGARAM1 WNK1	7.55e-05	225	67	5	12168954
Pubmed	CXXC finger protein 1 contains redundant functional domains that support embryonic stem cell cytosine methylation, histone methylation, and differentiation.	SETD1A SETD1B	7.63e-05	7	67	2	19433449
Pubmed	Homeobox gene Dlx3 is regulated by p63 during ectoderm development: relevance in the pathogenesis of ectodermal dysplasias.	DLX1 DLX2	7.63e-05	7	67	2	17164413
Pubmed	Sorting of striatal and cortical interneurons regulated by semaphorin-neuropilin interactions.	DLX1 DLX2	7.63e-05	7	67	2	11486090
Pubmed	Winged helix transcription factor BF-1 is essential for the development of the cerebral hemispheres.	DLX1 DLX2	7.63e-05	7	67	2	7605629
Pubmed	Null mutation of Dlx-2 results in abnormal morphogenesis of proximal first and second branchial arch derivatives and abnormal differentiation in the forebrain.	DLX1 DLX2	7.63e-05	7	67	2	7590232
Pubmed	Human transcription factor protein interaction networks.	SETD1A KMT2C FAM120A ZNF608 PRRC2C YLPM1 AUTS2 SP9 EMD HCFC2 SRRM2	8.40e-05	1429	67	11	35140242
Pubmed	E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins.	KMT2C ZBED4 OBSCN CEP295 LRRC7 EMD SSPOP CHRNB4	8.40e-05	736	67	8	29676528
Pubmed	Quantitative dissection and stoichiometry determination of the human SET1/MLL histone methyltransferase complexes.	SETD1A KMT2C SETD1B HCFC2	8.45e-05	119	67	4	23508102
Pubmed	Identification of motif-based interactions between SARS-CoV-2 protein domains and human peptide ligands pinpoint antiviral targets.	KMT2C MAST1 CEP295 SRRM2 SHROOM2	8.90e-05	233	67	5	37704626
Pubmed	Generation of regionally specified neurons in expanded glial cultures derived from the mouse and human lateral ganglionic eminence.	DLX1 DLX2	1.02e-04	8	67	2	11358480
Pubmed	Roles for Msx and Dlx homeoproteins in vertebrate development.	DLX1 DLX2	1.02e-04	8	67	2	10773441
Interaction	PHF20 interactions	SETD1A KMT2C SETD1B ZNF608 HCFC2	8.85e-07	53	67	5	int:PHF20
Interaction	ATN1 interactions	SETD1A KMT2C SETD1B ZNF608 AUTS2 HCFC2 SSPOP	2.88e-06	187	67	7	int:ATN1
Interaction	PHF20L1 interactions	SETD1A KMT2C SETD1B ZNF608 HCFC2	5.03e-06	75	67	5	int:PHF20L1
Interaction	SETD1B interactions	SETD1A KMT2C SETD1B ZNF608 HCFC2	5.03e-06	75	67	5	int:SETD1B
Interaction	KANSL3 interactions	SETD1A KMT2C SETD1B ZNF608 HCFC2	9.87e-06	86	67	5	int:KANSL3
Interaction	HCFC2 interactions	SETD1A KMT2C SETD1B ZNF608 HCFC2	1.37e-05	92	67	5	int:HCFC2
Interaction	RERE interactions	SETD1A SETD1B ZNF608 AUTS2 HCFC2	1.45e-05	93	67	5	int:RERE
Interaction	ZNF608 interactions	SETD1A SETD1B ZNF608 AUTS2 HCFC2	1.45e-05	93	67	5	int:ZNF608
Interaction	TOP3B interactions	SETD1A KMT2C SETD1B FAM120A ZBED4 TRIO CDK13 PPP1R9A OBSCN KIF14 ZFYVE26 DLX2 FGFR1 WNK1 PLEKHG5 MYRF	1.89e-05	1470	67	16	int:TOP3B
Interaction	EPB41L2 interactions	SETD1A TBCK MEPCE KIF14 SRRM2 WNK1 MAP3K2	5.99e-05	299	67	7	int:EPB41L2
Interaction	SP7 interactions	KMT2C ZNF608 YLPM1 SP9 DLX1 DLX2 EMD	6.65e-05	304	67	7	int:SP7
Interaction	KMT2B interactions	SETD1A KMT2C SETD1B ZNF608 HCFC2	7.25e-05	130	67	5	int:KMT2B
Interaction	WDR82 interactions	SETD1A KMT2C SETD1B OBSCN MEPCE HCFC2	7.58e-05	213	67	6	int:WDR82
Interaction	CXXC1 interactions	SETD1A KMT2C SETD1B ZNF608 HCFC2	7.79e-05	132	67	5	int:CXXC1
Interaction	KANSL2 interactions	SETD1A SETD1B ZNF608 HCFC2	8.67e-05	70	67	4	int:KANSL2
Interaction	YWHAB interactions	VPS13D MEPCE MAST1 KIF14 CRTC1 FGFR1 EMD SRRM2 WNK1 PLEKHG5 ARAP2 MAP3K2	1.14e-04	1014	67	12	int:YWHAB
Interaction	RBMX interactions	VPS13D FAM120A KHDRBS3 YLPM1 SEC23IP MEPCE KIF14 SRRM2	1.41e-04	461	67	8	int:RBMX
Interaction	ADA2 interactions	TRIO SRRM2	1.62e-04	6	67	2	int:ADA2
Interaction	PAXIP1 interactions	SETD1A KMT2C SETD1B MAST1 EMD HCFC2 SRRM2	1.86e-04	359	67	7	int:PAXIP1
Cytoband	2q32	DLX1 DLX2	1.89e-04	14	67	2	2q32
Cytoband	1p36.31	GPR153 PLEKHG5	1.89e-04	14	67	2	1p36.31
GeneFamily	Zinc fingers C2H2-type\|Lysine methyltransferases\|PR/SET domain family	SETD1A KMT2C SETD1B	7.63e-05	34	44	3	487
GeneFamily	PDZ domain containing	PPP1R9A MAST1 LRRC7 SHROOM2	5.02e-04	152	44	4	1220
GeneFamily	Blood group antigens\|CD molecules\|I-set domain containing\|Immunoglobulin like domain containing	NEO1 TRIO OBSCN FGFR1	6.23e-04	161	44	4	593
GeneFamily	Armadillo repeat containing\|Protein phosphatase 1 regulatory subunits	PPP1R9A YLPM1 WNK1 PTK2	9.65e-04	181	44	4	694
GeneFamily	CD molecules\|Mucins	MUC16 MUC20	1.18e-03	21	44	2	648
GeneFamily	Sterile alpha motif domain containing	PPP1R9A SEC23IP ARAP2	1.28e-03	88	44	3	760
GeneFamily	Pleckstrin homology domain containing\|Rho guanine nucleotide exchange factors\|C2 domain containing	TRIO OBSCN	1.12e-02	66	44	2	722
GeneFamily	NKL subclass homeoboxes and pseudogenes	DLX1 DLX2	1.16e-02	67	44	2	519
Coexpression	GSE27241_WT_VS_RORGT_KO_TH17_POLARIZED_CD4_TCELL_TREATED_WITH_DIGOXIN_UP	KMT2C FCHSD2 FAM120A PRRC2C TBCK KIF14 WNK1 ARAP2	1.95e-08	180	67	8	M8239
Coexpression	GSE12845_NAIVE_VS_DARKZONE_GC_TONSIL_BCELL_UP	VPS13D TRIO GPR153 PPP1R9A MEPCE MAP3K2	1.17e-05	198	67	6	M3200
ToppCell	droplet-Spleen-nan-18m\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ZNF608 PRRC2C FOSB DIAPH1 SRRM2 ARAP2	3.28e-07	182	67	6	eeb5dfa4539e9ca5220f26bc2b65717ddcf13b6c
ToppCell	droplet-Spleen-nan-18m-Lymphocytic\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ZNF608 PRRC2C FOSB DIAPH1 SRRM2 ARAP2	3.39e-07	183	67	6	28cbf909424f3be4491d49832f0aca0386560814
ToppCell	droplet-Spleen-nan-18m-Lymphocytic-nan\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ZNF608 PRRC2C FOSB DIAPH1 SRRM2 ARAP2	3.39e-07	183	67	6	3fa608aa6b119869ec3280dc388dfee57160e63a
ToppCell	human_hepatoblastoma\|World / Sample and Cell Type and Tumor Cluster (all cells)	PRRC2C PPP1R9A TBCK SRRM2 WNK1 PTK2	4.63e-07	193	67	6	e6a688bc834f845ff64dae1be64f073eec5091a1
ToppCell	(10)_Ciliated-(2)_GFP_FOXI1\|(10)_Ciliated / shred by cell type by condition	VPS13D FAM120A PRRC2C GLIS3 TOGARAM1 LYSMD3	5.54e-07	199	67	6	61b1ed2db71b96157b92b7535d1955a4033098da
ToppCell	Tracheal-NucSeq\|Tracheal / Cell types per location group and 10X technology with lineage, and cell group designations	KMT2C FCHSD2 TRIO PPP1R9A AUTS2 PTK2	5.54e-07	199	67	6	94b94b17ca18b8dc27b91da1f2ccf89e03cc7035
ToppCell	Entopeduncular-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Pvalb\|Entopeduncular / BrainAtlas - Mouse McCarroll V32	SKOR1 SP9 DLX1 DLX2	4.28e-06	72	67	4	7877184d5c9dd6d96476d71e7504e58c0b4d0f26
ToppCell	10x5'-Liver-Lymphocytic_Invariant-Inducer-like-ILC3\|Liver / Manually curated celltypes from each tissue	NEO1 ZNF608 PPP1R9A SHROOM2 BEGAIN	4.73e-06	163	67	5	7f61483eeb1fde21843c6391468e13cb0cc2a89f
ToppCell	TCGA-Ovary-Primary_Tumor-Ovarian_Carcinoma-Serous_Cystadenocarcinoma-5\|TCGA-Ovary / Sample_Type by Project: Shred V9	SETD1B ZNF608 PPP1R9A OBSCN MEPCE	5.17e-06	166	67	5	32d2eaf8a5d03881bf74d680825af2d5110b082d
ToppCell	cellseq2-Epithelial-Epithelial_Glandular-Goblet-Goblet\|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	ABCA13 MUC16 MYRF FAM83A MUC20	5.97e-06	171	67	5	25c1979e972c959e1ce4c57804f976f53a247ad7
ToppCell	cellseq2-Epithelial-Epithelial_Glandular-Goblet\|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	ABCA13 MUC16 MYRF FAM83A MUC20	5.97e-06	171	67	5	fe27bf581c75ef33c2848878e51ed16b275a4c8e
ToppCell	Brain_organoid-organoid_Kanton_Nature\|Brain_organoid / Sample Type, Dataset, Time_group, and Cell type.	PRRC2C SP9 MARCHF7 CEP295 SRRM2	8.75e-06	185	67	5	857c7ca8493e91ef1d0078ddafd6082020f9b169
ToppCell	droplet-Bladder-nan\|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PRRC2C FOSB DIAPH1 MARCHF7 SRRM2	9.21e-06	187	67	5	663991a8afe652e92363b64bcbd68c14d0307f0e
ToppCell	COVID-19-Epithelial_cells-Airway_goblet\|COVID-19 / group, cell type (main and fine annotations)	ABCA13 PPP1R9A GLIS3 MUC16 FAM83A	9.95e-06	190	67	5	51ca9ef4df3220487152fcf684147730637c7cc1
ToppCell	human_hepatoblastoma-Tumor_cells\|World / Sample and Cell Type and Tumor Cluster (all cells)	PPP1R9A TBCK SRRM2 WNK1 PTK2	1.05e-05	192	67	5	916fbec1c7ab7969bda711886ac88e877e30c280
ToppCell	Brain_organoid-organoid_Paulsen_bioRxiv-6_mon-Neuronal-INs\|6_mon / Sample Type, Dataset, Time_group, and Cell type.	GPR153 SP9 DLX1 DLX2 BEGAIN	1.16e-05	196	67	5	556e18eae05bf19259fe02848bcc9120aa2a9d29
ToppCell	wk_08-11-Epithelial-PNS\|wk_08-11 / Celltypes from embryonic and fetal-stage human lung	KHDRBS3 DLX1 DLX2 FAIM2 CHRNB4	1.19e-05	197	67	5	ce3f9feb6935f0e9daf13673b0a0d6e92817e187
ToppCell	Brain_organoid-organoid_Paulsen_bioRxiv-6_mon\|organoid_Paulsen_bioRxiv / Sample Type, Dataset, Time_group, and Cell type.	FOSB GLIS3 SP9 DLX1 DLX2	1.19e-05	197	67	5	58b957efd006f43c2fe55071d5c6d06c2e367e72
ToppCell	Parenchymal-NucSeq-Epithelial-Epi_airway_basal-Suprabasal\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	ABCA13 MUC16 FAM83A TPBG MUC20	1.21e-05	198	67	5	28ada093cec552262731194a04a4b9ff93186c3b
ToppCell	Parenchymal-NucSeq\|Parenchymal / Cell types per location group and 10X technology with lineage, and cell group designations	TRIO PPP1R9A GLIS3 AUTS2 PTK2	1.21e-05	198	67	5	1996373bdccc55aac347d349bd22f6aad6d0c668
ToppCell	proximal-3-Epithelial-Goblet\|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	ABCA13 MUC16 FAIM2 FAM83A MUC20	1.21e-05	198	67	5	3477202c4f702d8f75231b13d4b5216f56d981d7
ToppCell	Brain_organoid-organoid_Paulsen_bioRxiv-6_mon-Neuronal\|6_mon / Sample Type, Dataset, Time_group, and Cell type.	AUTS2 SP9 DLX1 LRRC7 DLX2	1.21e-05	198	67	5	076c862f2a723f0361749377561cae902068b1a0
ToppCell	proximal-Epithelial-Goblet-3\|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	ABCA13 MUC16 FAIM2 FAM83A MUC20	1.21e-05	198	67	5	da7b40eb00bb5e454e1cfcd1219dc0d84712592a
ToppCell	proximal-Epithelial-Goblet\|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	ABCA13 MUC16 FAIM2 FAM83A MUC20	1.21e-05	198	67	5	e7e1c430486a81280abc4a7e7f5bc3713dd20737
ToppCell	Tracheal-10x5prime-Epithelial-Epi_airway_secretory\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	ABCA13 MUC16 MYRF FAM83A MUC20	1.24e-05	199	67	5	7223f853335492ca617dbec3e4b6872a8a463a45
ToppCell	Tracheal-10x5prime-Epithelial-Epi_airway_secretory-Secretory_Goblet\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	ABCA13 MUC16 MYRF FAM83A MUC20	1.24e-05	199	67	5	e03bdc7cb825e287f41b834ec6061d23c1c03b04
ToppCell	LPS_IL1RA-Endothelial-Endothelial-Gen_Cap\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	KMT2C ZNF608 TRIO PPP1R9A PLEKHG5	1.27e-05	200	67	5	dccec522ab0d7fff62ad6273b02aa9022dbbb8eb
ToppCell	Brain_organoid-organoid_Tanaka_cellReport-3m-Neuronal-Interneuron\|3m / Sample Type, Dataset, Time_group, and Cell type.	ZNF608 SP9 DLX1 DLX2 SHROOM2	1.27e-05	200	67	5	a313b9a8bde1ea80a6eae183b76fba46b86558b4
ToppCell	COVID-19\|World / Disease, condition lineage and cell class	KMT2C CDK13 PRRC2C DIAPH1 SRRM2	1.27e-05	200	67	5	7dec470c379cd89f05a0f37c8628b21f136e52f0
ToppCell	Sigmoid-(1)_T_cell-(18)_cycling_gd_T\|Sigmoid / shred on region, Cell_type, and subtype	KIF14 CRTC1 ZFYVE26 PTK2 ARAP2	1.27e-05	200	67	5	6e367abd1a4b87e20eb9095b8337723163e8bbae
ToppCell	Fetal_brain-fetalBrain_Zhong_nature-GW23-Neuronal-GABAergic_neurons\|GW23 / Sample Type, Dataset, Time_group, and Cell type.	ZNF608 GPR153 OBSCN DLX1 DLX2	1.27e-05	200	67	5	c6bbd33bca86ac7a76a7ba704b3e141237d04549
ToppCell	mild\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	KMT2C CDK13 PRRC2C SRRM2 ARAP2	1.27e-05	200	67	5	12f1685ce8f218433068e090c9d839cd5a1910bf
ToppCell	Sigmoid-T_cell-cycling_gd_T\|Sigmoid / Region, Cell class and subclass	KIF14 CRTC1 ZFYVE26 PTK2 ARAP2	1.27e-05	200	67	5	9769185abae084ffac36420c749625e679b70ca8
ToppCell	Parenchymal-10x5prime-Epithelial-Epi_submucosal-gland\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	KHDRBS3 ABCA13 MUC16 MUC20	2.14e-05	108	67	4	75d635fc5bb004418db2e1328c24d96b718f10b1
ToppCell	Parenchymal-10x5prime-Epithelial-Epi_submucosal-gland-SMG_Duct\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	KHDRBS3 ABCA13 MUC16 MUC20	2.14e-05	108	67	4	9c7f3e25facfb54ef0be45044999bc36438bbea0
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW12-Neuronal-Interneuron\|GW12 / Sample Type, Dataset, Time_group, and Cell type.	DLX1 DLX2 HCFC2 MUC20	3.80e-05	125	67	4	eafc39072467e209c9fe3a4fa41cb09507a42e82
ToppCell	Posterior_cortex-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)\|Posterior_cortex / BrainAtlas - Mouse McCarroll V32	SP9 DLX1 DLX2 FAM83A	3.92e-05	126	67	4	84dce108561d4b745d19250c2ac0667d9e4ea17d
ToppCell	E16.5-samps-Mesenchymal-Matrix_fibroblast-_fetal-matrix_-_immature_3\|E16.5-samps / Age Group, Lineage, Cell class and subclass	NEO1 PRRC2C GLIS3 FAM83A	7.53e-05	149	67	4	651494e84be03dc7b061ebdfa91756a1c507b9b4
ToppCell	Posterior_cortex-Neuronal-Inhibitory-iN2(Gad1Gad2)\|Posterior_cortex / BrainAtlas - Mouse McCarroll V32	ZNF608 SP9 DLX1 DLX2	8.77e-05	155	67	4	105d59d8a1bb8cb37eef2c1767d737b2108ac7c5
ToppCell	Hippocampus-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)\|Hippocampus / BrainAtlas - Mouse McCarroll V32	PRRC2C SP9 DLX1 DLX2	1.02e-04	161	67	4	b81b346309f3facbfbebd91cae4c5b33c7bd24ef
ToppCell	wk_20-22-Hematologic_Lymphocytic-T_&_ILC-T_entry\|wk_20-22 / Celltypes from embryonic and fetal-stage human lung	KIF14 DLX2 CHRNB4 ARAP2	1.04e-04	162	67	4	a27750117e7f16a0bd07cc5f58a56becb39e800b
ToppCell	356C-Myeloid-Macrophage-FABP4+_Macrophage_4\|356C / Donor, Lineage, Cell class and subclass (all cells)	FCHSD2 KHDRBS3 KIF14 CRTC1	1.04e-04	162	67	4	7d43d59531cbefe3ac94953b7faf7156b2a31441
ToppCell	Children_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)-D046\|Children_(3_yrs) / Lineage, Cell type, age group and donor	ZNF608 FOSB PPP1R9A PTK2	1.14e-04	166	67	4	c20479fe7a4306320d7f26e78bf956225f00f35a
ToppCell	PCW_07-8.5-Neuronal-Neuronal_SCP-neuro_proliferating_SCP3_(1)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	KHDRBS3 DLX1 DLX2 ARAP2	1.17e-04	167	67	4	49b19159c62d33d65ed1e59a148c11ae902fd41c
ToppCell	Posterior_cortex-Neuronal-Inhibitory\|Posterior_cortex / BrainAtlas - Mouse McCarroll V32	PRRC2C SP9 DLX1 DLX2	1.17e-04	167	67	4	9a84f45345c75f2c8ff38a04245aadee2a26a240
ToppCell	PCW_05-06-Neuronal-Neuronal_SCP-neuro_proliferating_SCP3_(1)\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	KHDRBS3 DLX1 DLX2 ARAP2	1.22e-04	169	67	4	d9c3b22f62b882b8a2ea6fd9cf7afbe6d1775745
ToppCell	Frontal_cortex-Neuronal-Inhibitory\|Frontal_cortex / BrainAtlas - Mouse McCarroll V32	PRRC2C SP9 DLX1 DLX2	1.22e-04	169	67	4	78eb70dd916724e476eabccf18fb7fcec4210308
ToppCell	Hippocampus-Neuronal-Inhibitory-iN2(Gad1Gad2)\|Hippocampus / BrainAtlas - Mouse McCarroll V32	PRRC2C SP9 DLX1 DLX2	1.22e-04	169	67	4	c135d7ae0490d0024e0f4bd8c4ad42f6674a61da
ToppCell	Brain_organoid-organoid_Kanton_Nature-Organoid-1M-Proliferating-cycling_ventral_progenitors\|Organoid-1M / Sample Type, Dataset, Time_group, and Cell type.	ZBED4 SP9 DLX1 DLX2	1.25e-04	170	67	4	73601c873b177d5d134618d8e228c51381119f7d
ToppCell	facs-Brain_Non-Myeloid-Striatum_-18m-Epithelial-neuronal_stem_cell\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KIF14 SP9 DLX1 DLX2	1.31e-04	172	67	4	35c20de4db47dbf31c857d23c7a25cd7f95c085c
ToppCell	wk_15-18-Epithelial-PNS-Schwann_precursor\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	AUTS2 DLX1 DLX2 FAM83A	1.46e-04	177	67	4	5357359e6c2161a37f39a6b3b78449f5cbc327d1
ToppCell	Adult-Epithelial-club_cell-D175\|Adult / Lineage, Cell type, age group and donor	NEO1 KHDRBS3 GLIS3 FAM83A	1.46e-04	177	67	4	d652b7d84fe6aa38319d8d5adc72c70441bd0088
ToppCell	facs-Kidney-nan-24m-Epithelial-kidney_collecting_duct_epithelial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GLIS3 AUTS2 MSH4 MYRF	1.46e-04	177	67	4	2bf639e9e801e5144462ffc957f5739e0dfcd500
ToppCell	facs-Kidney-nan-24m-Epithelial-kidney_collecting_duct_epithelial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GLIS3 AUTS2 MSH4 MYRF	1.46e-04	177	67	4	9c7c6824b9011363851f084a500d665f025b026e
ToppCell	PCW_05-06-Neuronal-Neuronal_SCP-neuro_pre_proliferating_SCP_(4)\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	KHDRBS3 DLX1 DLX2 ARAP2	1.46e-04	177	67	4	59726bfd98f656fdcedf448a7e2e76a9bfad8285
ToppCell	droplet-Limb_Muscle-MUSCLE-30m\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PRRC2C DIAPH1 SRRM2 ARAP2	1.49e-04	178	67	4	01dafd19de04eff459253eaa9a35debf8f3deedf
ToppCell	droplet-Heart-nan-3m-Neuronal-cardiac_neuron\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PPP1R9A TBCK DLX1 DLX2	1.56e-04	180	67	4	da723df348d7b8449bb1124f23fe6fa706412adb
ToppCell	droplet-Heart-nan-3m-Neuronal\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PPP1R9A TBCK DLX1 DLX2	1.56e-04	180	67	4	5b146a94708b3c3610542a4d0925f3f7a2b19185
ToppCell	droplet-Heart-nan-3m-Neuronal-cardiac_neuron\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PPP1R9A TBCK DLX1 DLX2	1.56e-04	180	67	4	50758b1e7be2e43f83c10ab106900c067e61f5f7
ToppCell	E16.5-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT1-AT1_prolif\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	FCHSD2 EMD PLEKHG5 MYRF	1.59e-04	181	67	4	f6629fa71bb94405f523f63a9264cacf6d15c5f4
ToppCell	PCW_07-8.5-Neuronal-Neuronal_SCP-neuro_SCP_(0)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	KHDRBS3 DLX1 DLX2 ARAP2	1.59e-04	181	67	4	fad7ba168f541ac9d04edebc206f191e48bb7e99
ToppCell	droplet-Marrow-nan-3m-Hematologic\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PRRC2C FOSB DIAPH1 ARAP2	1.63e-04	182	67	4	1710eab3037a87609d21838be2d2d29c3bc36651
ToppCell	PCW_07-8.5-Neuronal-Neuronal_SCP-neuro_pre_proliferating_SCP_(4)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	KHDRBS3 DLX1 DLX2 ARAP2	1.63e-04	182	67	4	bfb725fff3d20066d8ac0a6ba2f88498fcbd876e
ToppCell	PCW_05-06-Neuronal-Neuronal_SCP-neuro_proliferating_SCP2_(1)\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	KHDRBS3 DLX1 DLX2 ARAP2	1.63e-04	182	67	4	f7f9be9c7ef8da9864d6aefe20043b26e1bb8697
ToppCell	PCW_05-06-Neuronal-Neuronal_SCP\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	KHDRBS3 DLX1 DLX2 ARAP2	1.63e-04	182	67	4	b4fc5e4f5d8440a3c9ee0a6fd0da87b43cabc8c6
ToppCell	E16.5-samps-Endothelial-Immature_fetal_endothelial-Intermediate_Endothelial\|E16.5-samps / Age Group, Lineage, Cell class and subclass	ZNF608 SHROOM2 PLEKHG5 ARAP2	1.63e-04	182	67	4	fec1caf867b1dc87b24504d895ee1a27df78062e
ToppCell	Children_(3_yrs)-Epithelial-lung_goblet_cell\|Children_(3_yrs) / Lineage, Cell type, age group and donor	ZNF608 GLIS3 MUC16 FAM83A	1.63e-04	182	67	4	3f1a666fe27dd7529c114539ed5f6b8ca585c875
ToppCell	droplet-Kidney-nan-3m-Epithelial-kidney_collecting_duct_epithelial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KHDRBS3 ABCA13 FGFR1 WNK1	1.63e-04	182	67	4	ccfee33de0faebbe69099d4ff3c3971f6a708b99
ToppCell	Hippocampus-Neuronal-Inhibitory\|Hippocampus / BrainAtlas - Mouse McCarroll V32	PRRC2C SP9 DLX1 DLX2	1.63e-04	182	67	4	b54ae650c04dfd0759c5f5e752b9bf684dd36516
ToppCell	droplet-Marrow-nan-3m-Myeloid-nan\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ZNF608 PRRC2C FOSB DIAPH1	1.63e-04	182	67	4	f8c73baaaca145e2efc48f10f636feb79c8fc779
ToppCell	droplet-Marrow-nan-3m-Hematologic-nan\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PRRC2C FOSB DIAPH1 ARAP2	1.63e-04	182	67	4	e78ba2c5cae480c16a596ce7c3bf2d480becacf4
ToppCell	PCW_05-06-Neuronal-Neuronal_SCP-neuro_SCP_(0)\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	KHDRBS3 DLX1 DLX2 ARAP2	1.66e-04	183	67	4	f517215ff45dec914af52dfdbc4579c19654c3aa
ToppCell	PCW_07-8.5-Neuronal-Neuronal_SCP-neuro_proliferating_SCP2_(1)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	KHDRBS3 DLX1 DLX2 ARAP2	1.66e-04	183	67	4	e0854864d377e158a4793088d1cb6b3dbf2c805d
ToppCell	wk_15-18-Epithelial-PNS-intermediate_Schwann\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	KHDRBS3 DLX1 DLX2 BEGAIN	1.66e-04	183	67	4	d874aa9a856f79626c8a8371f6196a77b7d662ee
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GUCY2F ABCA13 OBSCN SSPOP	1.70e-04	184	67	4	ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCell	Somatosensory_Cortex_(S1)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_C_(IT_L4_RORB)\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	KHDRBS3 GLIS3 ARAP2 TPBG	1.70e-04	184	67	4	6475a43201b136dcc9b113d2ca4cfa154ed9d65d
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GUCY2F ABCA13 OBSCN SSPOP	1.70e-04	184	67	4	2cbed6462fea2622871bb7e49b0df3d984239281
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GUCY2F ABCA13 OBSCN SSPOP	1.70e-04	184	67	4	2b19a8c5f823e00812908b23e66bb4e563278aff
ToppCell	droplet-Marrow-nan-3m\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ZNF608 PRRC2C FOSB DIAPH1	1.70e-04	184	67	4	1154a5ad7b8512272b7476f949ddac350910bfb7
ToppCell	droplet-Marrow-nan-3m-Myeloid\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ZNF608 PRRC2C FOSB DIAPH1	1.73e-04	185	67	4	7adfa929930cfa795cbfbd9f1a0b439e08aa765d
ToppCell	Children_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)\|Children_(3_yrs) / Lineage, Cell type, age group and donor	ZNF608 PPP1R9A AUTS2 PTK2	1.73e-04	185	67	4	98b8ee42b89d97e4c9db01740e0c193503c68f2c
ToppCell	PCW_07-8.5-Neuronal-Neuronal_SCP\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	KHDRBS3 DLX1 DLX2 ARAP2	1.73e-04	185	67	4	56c7a0dbf141728ac76b8c90af197719942ca67c
ToppCell	PCW_05-06-Neuronal-Neuronal_SCP-neuro_proliferating_SCP1_(1)\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	KHDRBS3 DLX1 DLX2 ARAP2	1.73e-04	185	67	4	a8946379fc066903fe8f4bc9cbf693b7b424a0cd
ToppCell	COVID-19-Epithelial_cells-Airway_club\|COVID-19 / group, cell type (main and fine annotations)	ZNF608 PPP1R9A GLIS3 PTK2	1.73e-04	185	67	4	cfe6fd73d817e173fe803bc1683c291d9bcb8608
ToppCell	primary_visual_cortex-Neuronal-GABAergic_neuron\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	ZNF608 SP9 DLX1 DLX2	1.73e-04	185	67	4	739260f8abebaf10a5cc49d91726278579e26170
ToppCell	PCW_07-8.5-Neuronal-Neuronal_postreplicative\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	DLX1 DLX2 FAIM2 CHRNB4	1.77e-04	186	67	4	2fdd0a80ad31cf017aafcf5dcf760ebd786b98c1
ToppCell	5'-GW_trimst-2-SmallIntestine-Neuronal-neuron_precursor-cycling_neuroblast\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	DLX1 DLX2 FBXO15 CHRNB4	1.77e-04	186	67	4	4fe8e0bf74c7dbf73634cafdacad89020d2634d0
ToppCell	Control-Epithelial-Club\|World / Disease state, Lineage and Cell class	ZNF608 PPP1R9A GLIS3 PTK2	1.77e-04	186	67	4	9798428691408e17ff2af2fe2d1b345f074d67e4
ToppCell	PCW_07-8.5-Neuronal-Neuronal_SCP-neuro_proliferating_SCP1_(1)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	KHDRBS3 DLX1 DLX2 ARAP2	1.77e-04	186	67	4	3113c85d0ac5fc46532c19b1bb71f34b985e1276
ToppCell	PCW_07-8.5-Neuronal\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	KHDRBS3 DLX1 DLX2 ARAP2	1.77e-04	186	67	4	7a4bb42f3f6a27b463e48eafc587d9ab3386f2fb
ToppCell	Control-Lymphoid-B\|Lymphoid / Disease state, Lineage and Cell class	FCHSD2 ZNF608 TRIO PTK2	1.81e-04	187	67	4	4e64be635f445276e71f2937f33f041c3a4204ab
ToppCell	PCW_05-06-Neuronal\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	KHDRBS3 DLX1 DLX2 ARAP2	1.81e-04	187	67	4	03a2ed85b171c887d4f3b0f4fe2e1cb4a853e658
ToppCell	Adult-Epithelial-alveolar_epithelial_cell_type_2-D175\|Adult / Lineage, Cell type, age group and donor	ABCA13 PPP1R9A GLIS3 AUTS2	1.84e-04	188	67	4	ec38def1fdbb34ed9b30244806975bd5a4370164
ToppCell	5'-GW_trimst-2-LargeIntestine-Neuronal-neuron_precursor-Neuroblast\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	MAST1 DLX1 DLX2 CHRNB4	1.84e-04	188	67	4	459e3fd4335a6f25f982d011b38702f4fcfed1cd
ToppCell	wk_08-11-Epithelial-PNS-MFNG+_DBH+_neuron\|wk_08-11 / Celltypes from embryonic and fetal-stage human lung	KHDRBS3 DLX1 DLX2 CHRNB4	1.84e-04	188	67	4	d3d7d21d4fa39ac4106a164652673de1bef8662d
ToppCell	droplet-Tongue-nan\|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PRRC2C DIAPH1 SRRM2 LYSMD3	1.84e-04	188	67	4	d62cc37e86b7b186e53aeb7f421c4e5ee28f23bd
ToppCell	5'-GW_trimst-2-LargeIntestine-Neuronal-neuron_precursor\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	MAST1 DLX1 DLX2 CHRNB4	1.84e-04	188	67	4	9fd262bbf6cdebfd945e39428a6059726fb55b3a
ToppCell	10x_3'_v2v3-Neoplastic-Stem-like-NPC-like-NPC-like_neural-B\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	GPR153 MAST1 DLX1 DLX2	1.88e-04	189	67	4	8e6b6025f5554672e26a5d19fe365acb4333789c
ToppCell	wk_15-18-Epithelial-PNS-PCP4+_neuron\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	DLX1 DLX2 FAIM2 CHRNB4	1.88e-04	189	67	4	22c927d2691b867fbdee1fbee042a6d3f7eadd7d
ToppCell	COVID-19-lung-Secretory\|lung / Disease (COVID-19 only), tissue and cell type	ZNF608 PPP1R9A GLIS3 FAM83A	1.88e-04	189	67	4	84d48e3ed25bebb8bb8074b3a2c5e2e88cff7f25
Drug	Bupivacaine hydrochloride [18010-40-7]; Down 200; 12.4uM; MCF7; HT_HG-U133A	VPS13D GPR153 YLPM1 FAM131A FGFR1 SRRM2	2.10e-05	191	67	6	7435_DN
Drug	Rapamycin; Down 200; 0.1uM; MCF7; HT_HG-U133A	TRIO GPR153 ZFYVE26 FGFR1 HCFC2 SRRM2	2.23e-05	193	67	6	6981_DN
Drug	Thioguanosine [85-31-4]; Down 200; 12.6uM; HL60; HT_HG-U133A	GPALPP1 VPS13D CDK13 PRRC2C YLPM1 FGFR1	2.30e-05	194	67	6	1264_DN
Drug	Esculin Hydrate [531-75-9]; Down 200; 11.8uM; MCF7; HT_HG-U133A	SETD1A ZBED4 CDK13 SEC23IP CRTC1 FGFR1	2.43e-05	196	67	6	5411_DN
Drug	Hymecromone [90-33-5]; Down 200; 22.8uM; MCF7; HT_HG-U133A	GPR153 AUTS2 CRTC1 FAM131A FGFR1 CAMTA2	2.43e-05	196	67	6	3383_DN
Drug	prochlorperazine dimaleate salt; Down 200; 10uM; MCF7; HT_HG-U133A	SETD1A VPS13D GPR153 CAMTA2 SRRM2 WNK1	2.50e-05	197	67	6	1640_DN
Drug	Pindolol [13523-86-9]; Up 200; 16.2uM; PC3; HT_HG-U133A	ZBED4 CRTC1 FAM131A FGFR1 MYRF MAP3K2	2.50e-05	197	67	6	2075_UP
Drug	Bucladesine sodium salt [16980-89-5]; Down 200; 7.8uM; PC3; HT_HG-U133A	FCHSD2 VPS13D ZBED4 FGFR1 SRRM2 MAP3K2	2.50e-05	197	67	6	5886_DN
Drug	Pepstatin A [26305-03-3]; Down 200; 5.8uM; MCF7; HT_HG-U133A	VPS13D TRIO PPP1R9A AUTS2 CRTC1 FAM131A	2.57e-05	198	67	6	3264_DN
Drug	Homosalate [118-56-9]; Up 200; 15.2uM; MCF7; HT_HG-U133A	SETD1B ZBED4 TRIO CRTC1 FGFR1 FAIM2	2.57e-05	198	67	6	3879_UP
Drug	Oxybutynin chloride [1508-65-2]; Down 200; 10.2uM; PC3; HT_HG-U133A	GPALPP1 SETD1B SEC23IP DIAPH1 MARCHF7 FGFR1	2.65e-05	199	67	6	7126_DN
Drug	Nifenazone [2139-47-1]; Up 200; 13uM; HL60; HG-U133A	VPS13D YLPM1 SEC23IP CRTC1 WNK1 PTK2	2.65e-05	199	67	6	1439_UP
Drug	Oleandomycin phosphate [7060-74-4]; Down 200; 5uM; PC3; HG-U133A	VPS13D SEC23IP DIAPH1 FGFR1 EMD ARAP2	2.65e-05	199	67	6	1935_DN
Drug	Pantothenic acid calcium salt monohydrate [63409-48-3]; Up 200; 8uM; MCF7; HT_HG-U133A	GPR153 PPP1R9A FAM131A MSH4 WNK1 BEGAIN	2.65e-05	199	67	6	4775_UP
Drug	Apramycin [37321-09-8]; Down 200; 7.4uM; MCF7; HT_HG-U133A	SETD1A VPS13D TRIO CDK13 YLPM1 WNK1	2.72e-05	200	67	6	4959_DN
Drug	IDN5109	CDK13 EMD TPBG	4.72e-05	24	67	3	CID006918412
Drug	Trichostatin A, from Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A	SETD1B CDK13 MEPCE SRRM2 PTK2	1.71e-04	176	67	5	2639_DN
Drug	Rapamycin; Up 200; 0.1uM; MCF7; HT_HG-U133A_EA	TRIO CDK13 GPR153 PPP1R9A ZFYVE26	2.16e-04	185	67	5	1022_UP
Drug	ICI 182,780; Down 200; 1uM; MCF7; HT_HG-U133A	VPS13D TRIO GPR153 CAMTA2 ARAP2	2.16e-04	185	67	5	6965_DN
Drug	colchicine; Up 200; 1uM; SKMEL5; HG-U133A	SETD1B PRRC2C FAM131A DLX2 FGFR1	2.44e-04	190	67	5	630_UP
Drug	Trifluridine [70-00-8]; Down 200; 13.6uM; MCF7; HT_HG-U133A	TRIO PRRC2C KIF14 FGFR1 SHROOM2	2.56e-04	192	67	5	7176_DN
Drug	Bisacodyl [603-50-9]; Down 200; 11uM; PC3; HT_HG-U133A	VPS13D YLPM1 SRRM2 SHROOM2 MYRF	2.62e-04	193	67	5	4616_DN
Drug	Menadione [58-27-5]; Down 200; 23.2uM; PC3; HT_HG-U133A	TRIO CDK13 FAM131A FGFR1 SHROOM2	2.68e-04	194	67	5	4662_DN
Drug	LY-171,883; Down 200; 1uM; MCF7; HG-U133A	FCHSD2 VPS13D PRRC2C FGFR1 MYRF	2.68e-04	194	67	5	222_DN
Drug	Methoxy-6-harmalan [3589-73-9]; Down 200; 18.6uM; MCF7; HT_HG-U133A	SETD1A VPS13D ZBED4 FGFR1 WNK1	2.75e-04	195	67	5	5455_DN
Drug	Erythromycin [114-07-8]; Up 200; 5.4uM; MCF7; HT_HG-U133A	VPS13D TRIO CDK13 FGFR1 MAP3K2	2.75e-04	195	67	5	5329_UP
Drug	Nefopam hydrochloride [23327-57-3]; Down 200; 13.8uM; MCF7; HT_HG-U133A	VPS13D CDK13 GPR153 CRTC1 CAMTA2	2.75e-04	195	67	5	2317_DN
Drug	Felodipine [72509-76-3]; Up 200; 10.4uM; PC3; HT_HG-U133A	SETD1A CDK13 CRTC1 DLX2 FGFR1	2.75e-04	195	67	5	6695_UP
Drug	radicicol, diheterospora chlamydosporia; Down 200; 0.1uM; MCF7; HT_HG-U133A	NEO1 DIAPH1 ZFYVE26 DLX2 CAMTA2	2.75e-04	195	67	5	6979_DN
Drug	Thioguanosine [85-31-4]; Down 200; 12.6uM; PC3; HT_HG-U133A	GPALPP1 SEC23IP HCFC2 WNK1 PTK2	2.75e-04	195	67	5	6643_DN
Drug	Furazolidone [67-45-8]; Down 200; 17.8uM; MCF7; HT_HG-U133A	VPS13D YLPM1 HCFC2 SRRM2 WNK1	2.75e-04	195	67	5	3358_DN
Drug	Cephalexin monohydrate [23325-78-2]; Down 200; 11uM; MCF7; HT_HG-U133A	FCHSD2 YLPM1 MARCHF7 FAM131A FGFR1	2.81e-04	196	67	5	5615_DN
Drug	Eucatropine hydrochloride [536-93-6]; Down 200; 12.2uM; MCF7; HT_HG-U133A	FCHSD2 VPS13D ZBED4 MARCHF7 ZFYVE26	2.81e-04	196	67	5	3416_DN
Drug	rosiglitazone; Down 200; 10uM; MCF7; HT_HG-U133A	SETD1A PPP1R9A CRTC1 ZFYVE26 WNK1	2.81e-04	196	67	5	5593_DN
Drug	GSK-3 Inhibitor IX; Up 200; 0.5uM; PC3; HT_HG-U133A	SETD1A CDK13 PRRC2C SRRM2 WNK1	2.81e-04	196	67	5	6559_UP
Drug	Nystatine [1400-61-9]; Up 200; 4.4uM; MCF7; HT_HG-U133A	KHDRBS3 TRIO GPR153 PPP1R9A BEGAIN	2.81e-04	196	67	5	4807_UP
Drug	Sulfamethoxypyridazine [80-35-3]; Up 200; 14.2uM; MCF7; HT_HG-U133A	SETD1A VPS13D TRIO DIAPH1 CRTC1	2.81e-04	196	67	5	3409_UP
Drug	Nitrarine dihydrochloride [20069-05-0]; Down 200; 10.6uM; PC3; HT_HG-U133A	FCHSD2 SETD1B GPR153 MARCHF7 SRRM2	2.81e-04	196	67	5	7382_DN
Drug	Nimesulide [51803-78-2]; Down 200; 13uM; PC3; HT_HG-U133A	PPP1R9A DIAPH1 FAM131A WNK1 MYRF	2.81e-04	196	67	5	2112_DN
Drug	Roxarsone [121-19-7]; Down 200; 15.2uM; HL60; HT_HG-U133A	VPS13D FGFR1 HCFC2 ARAP2 MAP3K2	2.81e-04	196	67	5	2950_DN
Drug	sodium 4-phenylbutyrate; Up 200; 1000uM; MCF7; HG-U133A	TRIO PRRC2C CRTC1 ZFYVE26 FGFR1	2.88e-04	197	67	5	407_UP
Drug	Piromidic acid [19562-30-2]; Down 200; 13.8uM; PC3; HT_HG-U133A	CRTC1 FAM131A FGFR1 WNK1 MAP3K2	2.88e-04	197	67	5	4575_DN
Drug	Lomefloxacin hydrochloride [98079-52-8]; Down 200; 10.4uM; PC3; HT_HG-U133A	SETD1A TRIO CDK13 MYRF MAP3K2	2.88e-04	197	67	5	3723_DN
Drug	Sotalol hydrochloride [959-24-0]; Down 200; 13uM; MCF7; HT_HG-U133A	SETD1A VPS13D KHDRBS3 ZBED4 GPR153	2.88e-04	197	67	5	4160_DN
Drug	SC 19220; Down 200; 10uM; MCF7; HT_HG-U133A	FCHSD2 VPS13D TRIO CDK13 MARCHF7	2.88e-04	197	67	5	7060_DN
Drug	Triflusal [322-79-2]; Down 200; 16.2uM; HL60; HG-U133A	VPS13D SEC23IP DIAPH1 CAMTA2 PTK2	2.88e-04	197	67	5	1717_DN
Drug	17-AAG; Down 200; 1uM; MCF7; HT_HG-U133A	GPALPP1 VPS13D TRIO CDK13 ARAP2	2.88e-04	197	67	5	6937_DN
Drug	prochlorperazine dimaleate salt; Down 200; 10uM; PC3; HT_HG-U133A	GPALPP1 ZBED4 YLPM1 SEC23IP SHROOM2	2.88e-04	197	67	5	1215_DN
Drug	Ketanserin tartrate hydrate [83846-83-7]; Up 200; 7uM; MCF7; HT_HG-U133A	SETD1B CDK13 AUTS2 WNK1 MYRF	2.88e-04	197	67	5	3209_UP
Drug	Alprostadil [745-65-3]; Down 200; 11.2uM; MCF7; HT_HG-U133A	SETD1A VPS13D CDK13 GPR153 MAP3K2	2.88e-04	197	67	5	7358_DN
Drug	Budesonide [51333-22-3]; Down 200; 9.2uM; MCF7; HT_HG-U133A	SETD1A ZBED4 YLPM1 SEC23IP FGFR1	2.95e-04	198	67	5	5431_DN
Drug	Azathioprine [446-86-6]; Up 200; 14.4uM; PC3; HT_HG-U133A	SETD1A CDK13 DIAPH1 FGFR1 SRRM2	2.95e-04	198	67	5	4667_UP
Drug	Levocabastine hydrochloride [79547-78-7]; Up 200; 8.8uM; MCF7; HT_HG-U133A	SETD1A CRTC1 FAM131A FGFR1 MYRF	2.95e-04	198	67	5	3509_UP
Drug	benserazide hydrochloride; Up 200; 10uM; SKMEL5; HG-U133A	FCHSD2 PRRC2C DLX2 FGFR1 CAMTA2	2.95e-04	198	67	5	631_UP
Drug	Sulfasalazine [599-79-1]; Down 200; 10uM; PC3; HT_HG-U133A	ZBED4 YLPM1 SRRM2 SHROOM2 MAP3K2	2.95e-04	198	67	5	6346_DN
Drug	troglitazone; Down 200; 10uM; MCF7; HT_HG-U133A	VPS13D SETD1B GPR153 YLPM1 ARAP2	2.95e-04	198	67	5	6991_DN
Drug	novobiocin sodium, USP; Up 200; 100uM; SKMEL5; HG-U133A	SETD1B YLPM1 FGFR1 CAMTA2 BEGAIN	2.95e-04	198	67	5	632_UP
Drug	cobalt(II) chloride hexahydrate; Down 200; 100uM; MCF7; HG-U133A	SEC23IP FGFR1 WNK1 PTK2 ARAP2	2.95e-04	198	67	5	383_DN
Drug	Proparacaine hydrochloride [5875-06-9]; Down 200; 12uM; PC3; HT_HG-U133A	TRIO PPP1R9A YLPM1 FAM131A SHROOM2	2.95e-04	198	67	5	6332_DN
Drug	Isoxsuprine hydrochloride [579-56-6]; Up 200; 11.8uM; MCF7; HT_HG-U133A	VPS13D CDK13 GPR153 CRTC1 WNK1	2.95e-04	198	67	5	4789_UP
Drug	GSK-3 Inhibitor IX; Down 200; 0.5uM; PC3; HT_HG-U133A	ZBED4 YLPM1 DLX2 SHROOM2 PTK2	2.95e-04	198	67	5	6559_DN
Drug	Piracetam [7491-74-9]; Up 200; 28.2uM; HL60; HG-U133A	GPALPP1 YLPM1 SEC23IP ZFYVE26 FGFR1	2.95e-04	198	67	5	1710_UP
Drug	arachidonic acid sodium salt; Up 200; 10uM; MCF7; HG-U133A	FCHSD2 ZBED4 GPR153 YLPM1 ZFYVE26	2.95e-04	198	67	5	441_UP
Drug	Imipenem [74431-23-5]; Up 200; 13.4uM; PC3; HT_HG-U133A	TRIO CDK13 CRTC1 MYRF MAP3K2	2.95e-04	198	67	5	7294_UP
Drug	Alverine citrate salt [5560-59-8]; Up 200; 8.4uM; PC3; HT_HG-U133A	SETD1A TRIO CRTC1 FGFR1 WNK1	2.95e-04	198	67	5	6345_UP
Drug	Acemetacin [53164-05-9]; Down 200; 9.6uM; MCF7; HT_HG-U133A	SETD1B DIAPH1 ZFYVE26 FAM131A FGFR1	2.95e-04	198	67	5	7442_DN
Drug	Streptomycin sulfate [3810-74-0]; Down 200; 2.8uM; PC3; HT_HG-U133A	VPS13D TRIO DLX2 CAMTA2 MAP3K2	2.95e-04	198	67	5	5837_DN
Drug	Indoprofen [31842-01-0]; Down 200; 14.2uM; MCF7; HT_HG-U133A	SETD1A GPR153 CRTC1 FGFR1 SRRM2	3.02e-04	199	67	5	3345_DN
Drug	Diltiazem hydrochloride [33286-22-5]; Down 200; 8.8uM; MCF7; HT_HG-U133A	FCHSD2 TRIO DLX2 FGFR1 PTK2	3.02e-04	199	67	5	5309_DN
Drug	Eucatropine hydrochloride [536-93-6]; Down 200; 12.2uM; PC3; HT_HG-U133A	SETD1A NEO1 DIAPH1 CRTC1 WNK1	3.02e-04	199	67	5	3759_DN
Drug	haloperidol; Down 200; 10uM; MCF7; HG-U133A	FCHSD2 VPS13D TRIO ZFYVE26 DLX2	3.02e-04	199	67	5	418_DN
Drug	rapamycin; Up 200; 0.1uM; HL60; HG-U133A	VPS13D NEO1 YLPM1 SEC23IP CRTC1	3.02e-04	199	67	5	362_UP
Drug	Pyrimethamine [58-14-0]; Up 200; 16uM; MCF7; HT_HG-U133A	SETD1A VPS13D ZBED4 CRTC1 FGFR1	3.09e-04	200	67	5	1474_UP
Drug	Hydroxyzine dihydrochloride [2192-20-3]; Up 200; 9uM; MCF7; HT_HG-U133A	TRIO GPR153 CRTC1 FGFR1 WNK1	3.09e-04	200	67	5	1524_UP
Disease	neurodevelopmental disorder with speech impairment and dysmorphic facies (implicated_via_orthology)	SETD1A SETD1B	5.08e-06	2	67	2	DOID:0070417 (implicated_via_orthology)
Disease	Metastatic melanoma	TRIO MAST1 PTK2	2.55e-04	54	67	3	C0278883
Disease	gait measurement	ZBTB22 AUTS2 KIF14 CRTC1	3.83e-04	150	67	4	EFO_0007680
Disease	Congenital Hypothyroidism	TPO GLIS3	3.90e-04	13	67	2	C0010308
Disease	prostate cancer (is_marker_for)	KMT2C CDK13 FGFR1 PTK2	4.45e-04	156	67	4	DOID:10283 (is_marker_for)
Disease	lung small cell carcinoma (is_marker_for)	PTK2 CHRNB4	5.97e-04	16	67	2	DOID:5409 (is_marker_for)
Disease	autosomal dominant intellectual developmental disorder (is_implicated_in)	TRIO SRRM2	6.76e-04	17	67	2	DOID:0060307 (is_implicated_in)
Disease	physical activity	SETD1B LRRC7 ARAP2	1.07e-03	88	67	3	EFO_0003940
Disease	multisite chronic pain	FAM120A MON1B PTK2	1.33e-03	95	67	3	EFO_0010100
Disease	Inhalant adrenergic use measurement	TRIO GLIS3 MUC16	1.37e-03	96	67	3	EFO_0009941
Disease	neurotic disorder	FAM120A YLPM1 GLIS3	1.59e-03	101	67	3	EFO_0004257
Disease	Epilepsy	SETD1A FOSB AUTS2	1.98e-03	109	67	3	C0014544
Disease	17-hydroxyprogesterone measurement	FAM161A FBXO15	1.98e-03	29	67	2	EFO_0010220

Protein segments in the cluster

Peptide	Gene	Start	Entry
EATATSTSPSNFYGN	CHRNB4	371	P30926
AGSLPTSSSYSSFSA	BEGAIN	291	Q9BUH8
SDGTFSVTSAYSSAP	CAMTA2	846	O94983
ERSNTPDSSYGSSFF	ABCA13	141	Q86UQ4
YPLSSTSGNADSSAV	ARAP2	451	Q8WZ64
SQPDGAYSSASSFSR	DLX1	51	P56177
SSASYGDDPTAQSLQ	DIAPH1	71	O60610
GSSPSSAASAFLGNY	DLX2	266	Q07687
SSSFSSAPYVSNDGL	CDK13	1341	Q14004
AASFSNASSASAPAY	MON1B	386	Q7L1V2
TSATEELYSSSPGFS	MUC16	9526	Q8WXI7
SSTIYSNSAESFLPG	KIF14	1226	Q15058
SQSSGTARSNTDPYS	KMT2C	2146	Q8NEZ4
STDLPYQAASSDSSA	HCFC2	391	Q9Y5Z7
AYVDPSSSSSYDNGF	FAIM2	66	Q9BWQ8
PANDSLAYSDSAGSF	LYSMD3	146	Q7Z3D4
QFSSYLTSPDVGFSS	MEPCE	646	Q7L2J0
FAGSSASSYSPSEAA	MUC20	566	Q8N307
TYSDYSPSQASSGSS	LRRC7	686	Q96NW7
SFGSFPYTPSADSNS	KIAA1109	1361	Q2LD37
LTSNNSSDSPTGSGY	KIAA1109	1931	Q2LD37
TSFLDASTVYGSSPA	TPO	321	P07202
SFLSSPSESSGYATL	GPR153	586	Q6NV75
SSGSSIFTPEYDDSR	MAP3K2	311	Q9Y2U5
LSDSSAPSSLGTGYF	AUTS2	206	Q8WXX7
DSSSLQSGTYFPVAS	FAM83A	96	Q86UY5
AYFPGSSTSSSSDND	FAM120A	451	Q9NZB2
DSAYLGASSQSSSPA	MAST1	1146	Q9Y2H9
AESQYLSSVDSFGSP	FOSB	21	P53539
AADATESSSYFSAQG	OBSCN	5226	Q5VST9
SSSSLYSPGSTLNYS	CRTC1	516	Q6UUV9
SPSNSSILSGSLDYS	COLCA2	36	A8K830
PSGSDTTYFSVNVSD	FGFR1	106	P11362
ATPSDSSSFLGQTYN	FBXO15	451	Q8NCQ5
PIFSSNYSSRSGTAA	GLIS3	556	Q8NEA6
VYDLPSSSSSLFGES	GLIS3	731	Q8NEA6
LSFSSGSLTPATYEN	GUCY2F	546	P51841
PPNYKSSSSDSSDSD	GPALPP1	36	Q8IXQ4
PSDSPAALESAFSSY	FAM131A	141	Q6UXB0
SESSRSNTQPGFSYS	MARCHF7	231	Q9H992
SNTQPGFSYSSSRDE	MARCHF7	236	Q9H992
SYDNSYSTPAQSGAD	KHDRBS3	286	O75525
PSSSAASSYSFSDLN	EMD	51	P50402
FDDSSSSPSGTLRNY	FCHSD2	456	O94868
TSFSEPDLGQSSSLY	FAM161A	156	Q3B820
SSSSSGISPDNRDFY	CEP295	2091	Q9C0D2
PDFLSEGSSSYNSAS	SKOR1	636	P84550
DSSSYPTVDSNSLLG	SRRM2	1141	Q9UQ35
PETGSSNAYASSFSL	SSPOP	2141	A2VEC9
GSLASLSSPADSYNE	PTK2	886	Q05397
DPEGATSSSYLASSQ	NEO1	1326	Q92859
VSSSASGPSTANYNS	PRRC2C	2281	Q9Y520
SGPSTANYNSFSSAS	PRRC2C	2286	Q9Y520
RDSAYGSFSTSSSTP	SHROOM2	206	Q13796
NSGGTPFSQDTAYSS	SETD1B	246	Q9UPS6
TFGASSSSARDTNYP	MSH4	101	O15457
SYFSQVSSSSDPFGN	SEC23IP	81	Q9Y6Y8
RGSTPYSQDSAYSSS	SETD1A	276	O15047
PTSSAFSSDYGGLFS	SP9	96	P0CG40
DSAYGTLSPTSLQDF	PLEKHG5	816	O94827
SDYLARDGPSSNSSF	nan	26	Q6ZSR9
SDSSGGRSSAPYFSA	TBCK	721	Q8TEA7
YSSFSSDQGLGESSA	YLPM1	711	P49750
GAESSAAKTSSPAYS	ZNF608	926	Q9ULD9
DLSPFAFSGSNASVS	TPBG	156	Q13641
SLSSSPNINSYSESG	TOGARAM1	1011	Q9Y4F4
SDNLYSAFTSDGAIS	WNK1	2191	Q9H4A3
DSLSSPGAANLFSTY	ZFYVE26	541	Q68DK2
SNYFSPRESTDFSSS	ZBTB22	206	O15209
LTPGSSDSLTASANY	TRIO	516	O75962
ANSPYATLASAESSS	ZBED4	521	O75132
YAAPDKNSSSSTIGS	VPS13D	2996	Q5THJ4
SDSLSGSYLDPNYQS	MYRF	336	Q9Y2G1
FTFNDDFSPSSTSSA	PPP1R9A	921	Q9ULJ8