Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
HumanPheno	Abnormal penis morphology	FRAS1 EVC2 PEX1 ZMYM2 REST ECE1 ZFPM2 USF3 NKX2-1 GLI2 GLI3 RAB3GAP2 TONSL PLAG1 PRKDC HERC1 MBD5 IL17RD TBL2 NOTCH2 TBCE	1.05e-06	712	50	21	HP:0000036
HumanPheno	Abnormality of the outer ear	FRAS1 EVC2 INTS1 TRMT1 PEX1 ZMYM2 RECQL ECE1 PREPL BRWD3 ZFPM2 TGM1 DST CLCN3 TENM3 GLI2 GLI3 RAB3GAP2 NUP133 PLAG1 ASXL2 PRKDC HERC1 MBD5 TBL2 NOTCH2 TBCE	2.58e-05	1337	50	27	HP:0000356
HumanPheno	Abnormal pinna morphology	FRAS1 EVC2 INTS1 TRMT1 PEX1 ZMYM2 RECQL ECE1 PREPL BRWD3 TGM1 DST CLCN3 TENM3 GLI2 GLI3 RAB3GAP2 NUP133 PLAG1 ASXL2 PRKDC HERC1 MBD5 TBL2 NOTCH2 TBCE	5.01e-05	1299	50	26	HP:0000377
HumanPheno	Micropenis	FRAS1 ECE1 ZFPM2 GLI2 GLI3 RAB3GAP2 PRKDC HERC1 MBD5 IL17RD TBCE	5.81e-05	278	50	11	HP:0000054
HumanPheno	Short stature	FLII EVC2 CARMIL2 L1CAM INTS1 PEX1 ZMYM2 RECQL ECE1 PREPL TGM1 USF3 NKX2-1 NFE2L2 GLI2 GLI3 RAB3GAP2 TONSL NUP133 SOHLH1 PLAG1 SNAPC4 MBD5 TBL2 NOTCH2 TBCE KNL1	6.90e-05	1407	50	27	HP:0004322
HumanPheno	Abnormal hand morphology	FLII FRAS1 EVC2 L1CAM PEX1 ZMYM2 RECQL ZFPM2 TGM1 DST CLCN3 GLI2 GLI3 RAB3GAP2 TONSL PLAG1 ASXL2 PRKDC HERC1 MBD5 TBL2 NOTCH2 TBCE	7.45e-05	1082	50	23	HP:0005922
HumanPheno	Hypoplasia of penis	FRAS1 ECE1 ZFPM2 GLI2 GLI3 RAB3GAP2 PLAG1 PRKDC HERC1 MBD5 IL17RD TBL2 TBCE	1.05e-04	408	50	13	HP:0008736
HumanPheno	External genital hypoplasia	FRAS1 PEX1 ECE1 ZFPM2 GLI2 GLI3 RAB3GAP2 SOHLH1 PLAG1 PRKDC HERC1 MBD5 IL17RD TBL2 TBCE	1.42e-04	544	50	15	HP:0003241
MousePheno	abnormal right lung accessory lobe morphology	ZFPM2 GLI2 GLI3	6.73e-06	5	124	3	MP:0009571
Domain	Leu-rich_rpt	LRRC8E PODNL1 FLII CARMIL2 LRTM1 CPN2 LGR5 ADGRA2 IGSF10 OPTC LINGO1 TONSL NLRC5 CD180 TBCE GP1BA GP5	1.22e-10	271	156	17	IPR001611
Domain	-	LRRC8E PODNL1 FLII CARMIL2 LRTM1 CPN2 LGR5 ADGRA2 IGSF10 OPTC LINGO1 TONSL NLRC5 CD180 LRRC73 TBCE GP1BA GP5	2.11e-10	321	156	18	3.80.10.10
Domain	L_dom-like	LRRC8E PODNL1 FLII CARMIL2 LRTM1 CPN2 LGR5 ADGRA2 IGSF10 OPTC LINGO1 TONSL NLRC5 CD180 LRRC73 TBCE GP1BA GP5	2.99e-10	328	156	18	IPR032675
Domain	LRR_8	LRRC8E PODNL1 FLII LRTM1 CPN2 LGR5 ADGRA2 IGSF10 OPTC LINGO1 CD180 GP1BA GP5	2.01e-09	171	156	13	PF13855
Domain	LRR_TYP	LRRC8E PODNL1 FLII LRTM1 CPN2 LGR5 ADGRA2 IGSF10 OPTC LINGO1 CD180 GP1BA GP5	3.07e-09	177	156	13	SM00369
Domain	Leu-rich_rpt_typical-subtyp	LRRC8E PODNL1 FLII LRTM1 CPN2 LGR5 ADGRA2 IGSF10 OPTC LINGO1 CD180 GP1BA GP5	3.07e-09	177	156	13	IPR003591
Domain	LRR	LRRC8E PODNL1 FLII LRTM1 CPN2 LGR5 ADGRA2 OPTC LINGO1 NLRC5 CD180 GP1BA GP5	1.43e-08	201	156	13	PS51450
Domain	LRRNT	PODNL1 LRTM1 CPN2 LGR5 IGSF10 OPTC LINGO1 GP1BA GP5	1.31e-07	98	156	9	IPR000372
Domain	LRRNT	PODNL1 LRTM1 CPN2 LGR5 IGSF10 OPTC LINGO1 GP1BA GP5	1.31e-07	98	156	9	SM00013
Domain	LRR_1	LRRC8E PODNL1 FLII LRTM1 CPN2 LGR5 ADGRA2 OPTC LINGO1 NLRC5 CD180 GP5	3.19e-07	219	156	12	PF00560
Domain	Cys-rich_flank_reg_C	LRTM1 CPN2 ADGRA2 IGSF10 LINGO1 CD180 GP1BA GP5	8.59e-07	90	156	8	IPR000483
Domain	LRRCT	LRTM1 CPN2 ADGRA2 IGSF10 LINGO1 CD180 GP1BA GP5	8.59e-07	90	156	8	SM00082
Domain	Leu-rich_rpt_4	PODNL1 FLII NLRC5	6.57e-05	10	156	3	IPR025875
Domain	LRR_4	PODNL1 FLII NLRC5	6.57e-05	10	156	3	PF12799
Domain	Oxysterol-bd_CS	OSBPL3 OSBPL7 OSBPL11	1.19e-04	12	156	3	IPR018494
Domain	Oxysterol_BP	OSBPL3 OSBPL7 OSBPL11	1.19e-04	12	156	3	PF01237
Domain	Oxysterol-bd	OSBPL3 OSBPL7 OSBPL11	1.19e-04	12	156	3	IPR000648
Domain	OSBP	OSBPL3 OSBPL7 OSBPL11	1.19e-04	12	156	3	PS01013
Domain	Ank_2	ANKRD31 ANKFY1 TRPC5 ANKMY1 NUDT12 ASB13 TONSL NOTCH2	4.57e-04	215	156	8	PF12796
Domain	Ank	ANKRD31 ANKFY1 TRPC5 ANKMY1 NUDT12 ASB13 TONSL NOTCH2	6.73e-04	228	156	8	PF00023
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	LRRC8E FLII FRAS1 MYO10 UBR4 L1CAM INTS1 TRMT1 ECE1 ADGRA2 CNTROB NHSL1 DST ADAMTSL5 IFRD2 NLRC5 PRKDC HERC1 SNAPC4 MBD5 IL17RD NOTCH2	1.08e-08	1105	162	22	35748872
Pubmed	The SOX2-interactome in brain cancer cells identifies the requirement of MSI2 and USP9X for the growth of brain tumor cells.	UBR4 INTS1 USP24 ZMYM2 CHD9 CLOCK INTS2 GLI3 OSBPL11 QSER1 KNL1	9.92e-08	282	162	11	23667531
Pubmed	Gli3 is a negative regulator of Tas1r3-expressing taste cells.	LGR5 GLI3 POU2F3	3.95e-07	4	162	3	29415007
Pubmed	Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.	ANKFY1 KIAA0232 ADGRA2 PASK DST NRXN2 RAB3GAP2 ERC2 DOP1B	1.21e-06	225	162	9	12168954
Pubmed	A systems-wide screen identifies substrates of the SCFβTrCP ubiquitin ligase.	FLII MTERF3 PEX1 REST DENND4C NFE2L2 GLI3 USP54 KNL1	1.56e-06	232	162	9	25515538
Pubmed	Molecular embryology of the lung: then, now, and in the future.	NKX2-1 GLI2 GLI3	1.96e-06	6	162	3	10330024
Pubmed	The human and murine protocadherin-beta one-exon gene families show high evolutionary conservation, despite the difference in gene number.	PCDHB6 PCDHB4 PCDHB2 PCDHB18P	2.07e-06	20	162	4	11322959
Pubmed	H4K20me0 recognition by BRCA1-BARD1 directs homologous recombination to sister chromatids.	EEF1E1 INTS1 ZMYM2 REST SIX4 CLOCK MSL2 INTS6 NOP9 DST INTS2 NFE2L2 OSBPL3 TONSL NUP133 ASXL2 PRKDC QSER1 TBL2 GNL3	2.78e-06	1294	162	20	30804502
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	FRAS1 ANKFY1 MYO10 KIAA0232 HEATR5A CSMD3 TENM3 RAB3GAP2 ERC2 ASXL2 DOP1B	3.63e-06	407	162	11	12693553
Pubmed	A census of human transcription factors: function, expression and evolution.	ADNP2 HSFY1 REST SIX4 CLOCK ZFPM2 USF3 NKX2-1 NFE2L2 GLI2 GLI3 TOX3 SOHLH1 PLAG1 SNAPC4 POU2F3	5.88e-06	908	162	16	19274049
Pubmed	Resolution of cell fate decisions revealed by single-cell gene expression analysis from zygote to blastocyst.	ANKFY1 MTERF3 ZMYM2 REST SIX4 CLOCK NKX2-1 NFE2L2 GLI3 TOX3 PLAG1 SNAPC4 ABLIM2 POU2F3 DOP1B	6.29e-06	808	162	15	20412781
Pubmed	Clustered gamma-protocadherins regulate cortical interneuron programmed cell death.	PCDHB6 PCDHB4 PCDHB2 PCDHB18P NKX2-1	7.10e-06	57	162	5	32633719
Pubmed	CTCF Governs the Identity and Migration of MGE-Derived Cortical Interneurons.	PCDHB6 PCDHB4 PCDHB2 PCDHB18P NKX2-1	7.74e-06	58	162	5	30377227
Pubmed	Mouse Gli1 mutants are viable but have defects in SHH signaling in combination with a Gli2 mutation.	NKX2-1 GLI2 GLI3	8.16e-06	9	162	3	10725236
Pubmed	Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein.	FRAS1 CEP85 PEX1 COX15 ECE1 NOP9 DST CLCN3 OSBPL3 TONSL MARF1 OSBPL11 QSER1	1.23e-05	650	162	13	38777146
Pubmed	Linx mediates interaxonal interactions and formation of the internal capsule.	L1CAM ZFPM2 NKX2-1	1.59e-05	11	162	3	24930700
Pubmed	The OSBP-related protein family in humans.	OSBPL3 OSBPL7 OSBPL11	1.59e-05	11	162	3	11483621
Pubmed	CPLANE protein INTU regulates growth and patterning of the mouse lungs through cilia-dependent Hh signaling.	NKX2-1 GLI2 GLI3	1.59e-05	11	162	3	39029571
Pubmed	A human MAP kinase interactome.	CCDC186 KIAA0232 ADNP2 ZMYM2 MSL2 USF3 DST CDC42EP2 PRKDC ABLIM2 MBD5	1.91e-05	486	162	11	20936779
Pubmed	Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.	FBF1 ADNP2 PEX1 CHD9 FASTKD5 BRWD3 ARG2 PASK INTS6 MTUS1 OSBPL3 GLI3 USP54 CSMD1 GNL3 NOTCH2 KNL1	1.96e-05	1116	162	17	31753913
Pubmed	A family of 12 human genes containing oxysterol-binding domains.	OSBPL3 OSBPL7 OSBPL11	2.12e-05	12	162	3	11735225
Pubmed	Congenital diaphragmatic hernia: comparison of animal models and relevance to the human situation.	ZFPM2 GLI2 GLI3	2.12e-05	12	162	3	19325248
Pubmed	An oxysterol-binding protein family identified in the mouse.	OSBPL3 OSBPL7 OSBPL11	2.12e-05	12	162	3	12215260
Pubmed	Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.	KIAA0232 PPFIA2 CHD9 ANKMY1 BRWD3 OPRL1 INTS6 USF3 INTS2 GLI2 TOX3 RASGEF1C NLRC5 QSER1 CSMD1 ABLIM2 MBD5 ZRANB1 GNL3 NOTCH2	2.16e-05	1489	162	20	28611215
Pubmed	A novel protein-processing domain in Gli2 and Gli3 differentially blocks complete protein degradation by the proteasome.	GLI2 GLI3	2.16e-05	2	162	2	17283082
Pubmed	New mouse models of congenital anorectal malformations.	GLI2 GLI3	2.16e-05	2	162	2	10693670
Pubmed	CD150 and CD180 are involved in regulation of transcription factors expression in chronic lymphocytic leukemia cells.	SLAMF1 CD180	2.16e-05	2	162	2	29284783
Pubmed	Neurodegenerative changes are prevented by Erythropoietin in the pmn model of motoneuron degeneration.	GLI3 TBCE	2.16e-05	2	162	2	24769002
Pubmed	Differential effects of GLI2 and GLI3 in regulating cervical cancer malignancy in vitro and in vivo.	GLI2 GLI3	2.16e-05	2	162	2	29967343
Pubmed	Kinetics of hedgehog-dependent full-length Gli3 accumulation in primary cilia and subsequent degradation.	GLI2 GLI3	2.16e-05	2	162	2	20154143
Pubmed	Migration of myeloid cells during inflammation is differentially regulated by the cell surface receptors Slamf1 and Slamf8.	SLAMF8 SLAMF1	2.16e-05	2	162	2	25799045
Pubmed	The mouse mutation progressive motor neuronopathy (pmn) maps to chromosome 13.	GLI3 TBCE	2.16e-05	2	162	2	8530062
Pubmed	Normal exon copy number of the GLI2 and GLI3 genes in patients with esophageal atresia.	GLI2 GLI3	2.16e-05	2	162	2	23442119
Pubmed	Adult Gli2+/-;Gli3Δ699/+ Male and Female Mice Display a Spectrum of Genital Malformation.	GLI2 GLI3	2.16e-05	2	162	2	27814383
Pubmed	CD150 and CD180 are negative regulators of IL-10 expression and secretion in chronic lymphocytic leukemia B cells.	SLAMF1 CD180	2.16e-05	2	162	2	33904315
Pubmed	The interplay of CD150 and CD180 receptor pathways contribute to the pathobiology of chronic lymphocytic leukemia B cells by selective inhibition of Akt and MAPK signaling.	SLAMF1 CD180	2.16e-05	2	162	2	28982149
Pubmed	A study on etiology of incontinence in double knockout mouse model.	GLI2 GLI3	2.16e-05	2	162	2	36272934
Pubmed	Functional proteomics mapping of a human signaling pathway.	EVC2 UBR4 ZMYM2 FAM161B MAN1A2 DST TENM3 PLAG1 ASXL2 HERC1 NOTCH2 KNL1	2.31e-05	591	162	12	15231748
Pubmed	Protocadherins.	PCDHB6 PCDHB4 PCDHB2	2.74e-05	13	162	3	12231349
Pubmed	Ptch2/Gas1 and Ptch1/Boc differentially regulate Hedgehog signalling in murine primordial germ cell migration.	GLI2 GLI3 FUT4	2.74e-05	13	162	3	32332736
Pubmed	Morphogenesis of the trachea and esophagus: current players and new roles for noggin and Bmps.	NKX2-1 GLI2 GLI3	2.74e-05	13	162	3	16916379
Pubmed	Elucidation of N-glycosylation sites on human platelet proteins: a glycoproteomic approach.	ECE1 F5 GP1BA GP5	2.96e-05	38	162	4	16263699
Pubmed	Defining the membrane proteome of NK cells.	MAN2A1 CARMIL2 UBR4 INTS1 RECQL ECE1 F5 MAN1A2 ATP8A1 CLCN3 INTS2 OSBPL3 MARF1 NUP133 PRKDC GNL3 NOTCH2	3.47e-05	1168	162	17	19946888
Pubmed	The Human Integrator Complex Facilitates Transcriptional Elongation by Endonucleolytic Cleavage of Nascent Transcripts.	INTS1 INTS6 INTS2	3.48e-05	14	162	3	32697989
Pubmed	Structure of the catalytic core of the Integrator complex.	INTS1 INTS6 INTS2	3.48e-05	14	162	3	33548203
Pubmed	Sonic hedgehog regulates branching morphogenesis in the mammalian lung.	NKX2-1 GLI2 GLI3	3.48e-05	14	162	3	9768363
Pubmed	INTS10-INTS13-INTS14 form a functional module of Integrator that binds nucleic acids and the cleavage module.	INTS1 INTS6 INTS2	3.48e-05	14	162	3	32647223
Pubmed	The protein network surrounding the human telomere repeat binding factors TRF1, TRF2, and POT1.	MYO10 TRPC5 F5 DST MARF1 RASGEF1C OSBPL11	4.09e-05	197	162	7	20811636
Pubmed	Characterization of an exchangeable gene trap using pU-17 carrying a stop codon-beta geo cassette.	CEP85 MYO10 L1CAM REST INTS6 TENM3 OSBPL3 GLI2 OSBPL11 MBD5 NOTCH2	4.64e-05	536	162	11	15840001
Pubmed	Exchangeable gene trap using the Cre/mutated lox system.	CEP85 MYO10 L1CAM REST INTS6 TENM3 OSBPL3 GLI2 OSBPL11 MBD5 NOTCH2	4.80e-05	538	162	11	10512203
Pubmed	Protein interaction network of the mammalian Hippo pathway reveals mechanisms of kinase-phosphatase interactions.	CEP85 FBF1 CNTROB DENND4C NEK4 DST CCSER2 PRKDC USP54 NOTCH2	4.97e-05	446	162	10	24255178
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	CARMIL2 KIAA0232 PABIR2 DENND4C NEK4 NHSL1 DST MTUS1 OSBPL3 RAB3GAP2 CCSER2 USP54 NOTCH2 DOP1B	5.50e-05	861	162	14	36931259
Pubmed	Proper ciliary assembly is critical for restricting Hedgehog signaling during early eye development in mice.	NKX2-1 GLI2 GLI3	6.43e-05	17	162	3	28778798
Pubmed	Signaling and regulation of the platelet glycoprotein Ib-IX-V complex.	F5 GP1BA	6.45e-05	3	162	2	17414217
Pubmed	Murine models of VACTERL syndrome: Role of sonic hedgehog signaling pathway.	GLI2 GLI3	6.45e-05	3	162	2	11172440
Pubmed	Identification of two new members of the CSMD gene family.	CSMD3 CSMD1	6.45e-05	3	162	2	12906867
Pubmed	Fuzzy modeling reveals a dynamic self-sustaining network of the GLI transcription factors controlling important metabolic regulators in adult mouse hepatocytes.	GLI2 GLI3	6.45e-05	3	162	2	26010061
Pubmed	Pharmacogenomic association of nonsynonymous SNPs in SIGLEC12, A1BG, and the selectin region and cardiovascular outcomes.	SIGLEC12 F5	6.45e-05	3	162	2	23690342
Pubmed	Liprin-α3 controls vesicle docking and exocytosis at the active zone of hippocampal synapses.	PPFIA2 ERC2	6.45e-05	3	162	2	29439199
Pubmed	Genome-wide analysis of repressor element 1 silencing transcription factor/neuron-restrictive silencing factor (REST/NRSF) target genes.	L1CAM REST	6.45e-05	3	162	2	15240883
Pubmed	Genome-wide association meta-analysis of circulating odd-numbered chain saturated fatty acids: Results from the CHARGE Consortium.	MYO10 DLEU1	6.45e-05	3	162	2	29738550
Pubmed	Gli family members are differentially expressed during the mitotic phase of spermatogenesis.	GLI2 GLI3	6.45e-05	3	162	2	9178901
Pubmed	Crystal structure of a five-finger GLI-DNA complex: new perspectives on zinc fingers.	GLI2 GLI3	6.45e-05	3	162	2	8378770
Pubmed	Inhibition of fatty acid amide hydrolase activates Nrf2 signalling and induces heme oxygenase 1 transcription in breast cancer cells.	FAAH NFE2L2	6.45e-05	3	162	2	23347118
Pubmed	Human platelet glycoprotein V: characterization of the polypeptide and the related Ib-V-IX receptor system of adhesive, leucine-rich glycoproteins.	GP1BA GP5	6.45e-05	3	162	2	7690959
Pubmed	Ursodeoxycholic acid stimulates Nrf2-mediated hepatocellular transport, detoxification, and antioxidative stress systems in mice.	NFE2L2 PRKDC	6.45e-05	3	162	2	18687751
Pubmed	A mouse model of greig cephalopolysyndactyly syndrome: the extra-toesJ mutation contains an intragenic deletion of the Gli3 gene.	GLI2 GLI3	6.45e-05	3	162	2	8387379
Pubmed	Positive regulation of Hedgehog signaling via phosphorylation of GLI2/GLI3 by DYRK2 kinase.	GLI2 GLI3	6.45e-05	3	162	2	38968120
Pubmed	Unique and complimentary activities of the Gli transcription factors in Hedgehog signaling.	GLI2 GLI3	6.45e-05	3	162	2	16571352
Pubmed	Axo-axonic Innervation of Neocortical Pyramidal Neurons by GABAergic Chandelier Cells Requires AnkyrinG-Associated L1CAM.	L1CAM NKX2-1	6.45e-05	3	162	2	30846310
Pubmed	Different expression patterns of Gli1-3 in mouse embryonic maxillofacial development.	GLI2 GLI3	6.45e-05	3	162	2	22178118
Pubmed	Genetic variation in the epidermal transglutaminase genes is not associated with atopic dermatitis.	TGM5 TGM1	6.45e-05	3	162	2	23189155
Pubmed	Subfamily III of mammalian oxysterol-binding protein (OSBP) homologues: the expression and intracellular localization of ORP3, ORP6, and ORP7.	OSBPL3 OSBPL7	6.45e-05	3	162	2	14593528
Pubmed	Multiple Ser/Thr-rich degrons mediate the degradation of Ci/Gli by the Cul3-HIB/SPOP E3 ubiquitin ligase.	GLI2 GLI3	6.45e-05	3	162	2	19955409
Pubmed	Interaction of calmodulin with the cytoplasmic domain of the platelet membrane glycoprotein Ib-IX-V complex.	GP1BA GP5	6.45e-05	3	162	2	11468167
Pubmed	Isolation of a mouse Golgi mannosidase cDNA, a member of a gene family conserved from yeast to mammals.	MAN2A1 MAN1A2	6.45e-05	3	162	2	8144579
Pubmed	Internal ribosome entry site-based attenuation of a flavivirus candidate vaccine and evaluation of the effect of beta interferon coexpression on vaccine properties.	PRKDC MX1	6.45e-05	3	162	2	24307589
Pubmed	NRF2 regulates core and stabilizing circadian clock loops, coupling redox and timekeeping in Mus musculus.	CLOCK NFE2L2	6.45e-05	3	162	2	29481323
Pubmed	Sonic hedgehog through Gli2 and Gli3 is required for the proper development of placental labyrinth.	GLI2 GLI3	6.45e-05	3	162	2	25695606
Pubmed	Protein interactome reveals converging molecular pathways among autism disorders.	DBF4B KIAA0232 PPFIA2 FBF1 CNTROB ZFPM2 LINGO1 NUP133 LRRC73 NOTCH2 MX1	6.86e-05	560	162	11	21653829
Pubmed	A High-Density Human Mitochondrial Proximity Interaction Network.	FLII CEP85 UBR4 MTERF3 TRMT1 PEX1 COX15 FASTKD5 PREPL ARG2 DST OSBPL3 RAB3GAP2 TOX3 NUP133 OSBPL11 HERC1 TBL2 GNL3	7.40e-05	1496	162	19	32877691
Pubmed	Coordination of canonical and noncanonical Hedgehog signalling pathways mediated by WDR11 during primordial germ cell development.	GLI2 GLI3 FUT4	9.10e-05	19	162	3	37516749
Pubmed	Pathfinding of corticothalamic axons relies on a rendezvous with thalamic projections.	L1CAM ZFPM2 NKX2-1	9.10e-05	19	162	3	23395374
Pubmed	Wnt2/2b and beta-catenin signaling are necessary and sufficient to specify lung progenitors in the foregut.	NKX2-1 GLI2 GLI3	9.10e-05	19	162	3	19686689
Pubmed	Specific requirement of Gli transcription factors in Hedgehog-mediated intestinal development.	LGR5 GLI2 GLI3	9.10e-05	19	162	3	23645682
Pubmed	Cell cycle-related kinase regulates mammalian eye development through positive and negative regulation of the Hedgehog pathway.	NKX2-1 GLI2 GLI3	9.10e-05	19	162	3	29166577
Pubmed	The ciliary G-protein-coupled receptor Gpr161 negatively regulates the Sonic hedgehog pathway via cAMP signaling.	NKX2-1 GLI2 GLI3	9.10e-05	19	162	3	23332756
Pubmed	Pro-prion, as a membrane adaptor protein for E3 ligase c-Cbl, facilitates the ubiquitination of IGF-1R, promoting melanoma metastasis.	PODNL1 NBEAL1 CCDC186 UBR4 MTERF3 INTS1 ADNP2 NHSL1 OSBPL3 RAB3GAP2 ASXL2 MBD5	1.00e-04	689	162	12	36543142
Pubmed	Myh10 deficiency leads to defective extracellular matrix remodeling and pulmonary disease.	MYO10 NKX2-1 GLI2 GLI3	1.03e-04	52	162	4	30389913
Pubmed	Patterning of ventral telencephalon requires positive function of Gli transcription factors.	NKX2-1 GLI2 GLI3	1.07e-04	20	162	3	19632216
Pubmed	Pinin modulates expression of an intestinal homeobox gene, Cdx2, and plays an essential role for small intestinal morphogenesis.	LCT GLI2 GLI3	1.07e-04	20	162	3	20637749
Pubmed	Mammalian APE1 controls miRNA processing and its interactome is linked to cancer RNA metabolism.	FLII DBF4B TRMT1 CHD9 REST CNTROB PABIR2 INSYN2A NUDT12 TGM1 CLCN3 OSBPL7 TBCE GP1BA	1.17e-04	925	162	14	28986522
Pubmed	Sonic hedgehog regulates growth and morphogenesis of the tooth.	L1CAM GLI2 GLI3	1.24e-04	21	162	3	11044393
Pubmed	Single cell transcriptomics identifies a signaling network coordinating endoderm and mesoderm diversification during foregut organogenesis.	NKX2-1 GLI2 GLI3	1.24e-04	21	162	3	32855417
Pubmed	Cloning and sequencing of the mouse Gli2 gene: localization to the Dominant hemimelia critical region.	GLI2 GLI3	1.29e-04	4	162	2	9027508
Pubmed	Comparative genomics identification of a novel set of temporally regulated hedgehog target genes in the retina.	GLI2 GLI3	1.29e-04	4	162	2	22281533
Pubmed	Human kininogens regulate thrombin binding to platelets through the glycoprotein Ib-IX-V complex.	GP1BA GP5	1.29e-04	4	162	2	9269768
Pubmed	Aspirin induces platelet receptor shedding via ADAM17 (TACE).	GP1BA GP5	1.29e-04	4	162	2	16179345
Pubmed	Bernard-Soulier syndrome: an update.	GP1BA GP5	1.29e-04	4	162	2	23929303
Pubmed	Hedgehog pathway dysregulation contributes to the pathogenesis of human gastrointestinal stromal tumors via GLI-mediated activation of KIT expression.	GLI2 GLI3	1.29e-04	4	162	2	27793025
Interaction	NUP43 interactions	ZMYM2 CHD9 CCDC168 CSMD3 MSL2 DST ATP8A1 NKX2-1 RAB3GAP2 TOX3 TONSL CCSER2 MARF1 NUP133 ASXL2 ZRANB1 GNL3 KNL1	2.51e-06	625	160	18	int:NUP43
Cytoband	3p14.3	LRTM1 ERC2 IL17RD	1.63e-04	30	162	3	3p14.3
GeneFamily	Oxysterol binding proteins\|Pleckstrin homology domain containing	OSBPL3 OSBPL7 OSBPL11	3.38e-05	12	99	3	670
GeneFamily	Integrator complex	INTS1 INTS6 INTS2	6.91e-05	15	99	3	1366
GeneFamily	Blood group antigens\|CD molecules\|I-set domain containing\|Immunoglobulin like domain containing	SIGLEC12 L1CAM IGDCC3 IGSF10 LINGO1 SIGLEC6	2.57e-04	161	99	6	593
GeneFamily	Ankyrin repeat domain containing	ANKRD31 ANKFY1 ANKMY1 NUDT12 ASB13 TONSL NOTCH2	3.69e-04	242	99	7	403
GeneFamily	Clustered protocadherins	PCDHB6 PCDHB4 PCDHB2 PCDHB18P	4.18e-04	64	99	4	20
GeneFamily	Transglutaminases	TGM5 TGM1	1.04e-03	9	99	2	773
GeneFamily	ADAM metallopeptidase domain containing\|CD molecules	SLAMF8 L1CAM SLAMF1 SIGLEC6 FUT4 CD180 GP1BA GP5	1.44e-03	394	99	8	471
Coexpression	MANNO_MIDBRAIN_NEUROTYPES_HGABA	CCDC186 PPFIA2 L1CAM PCDHB4 PEX1 GPRIN3 LGR5 CSMD3 PREPL INSYN2A ZFPM2 ATP8A1 LINGO1 NRXN2 MTUS1 TOX3 ERC2 HERC1 CSMD1 DOP1B	1.72e-05	1106	162	20	M39071
Coexpression	GSE22886_CD8_VS_CD4_NAIVE_TCELL_DN	PODNL1 INTS1 FASTKD5 ECE1 F5 SIGLEC6 OAZ3 GP1BA	3.13e-05	196	162	8	M4404
Coexpression	GSE25088_WT_VS_STAT6_KO_MACROPHAGE_IL4_STIM_UP	CEP85 DBF4B INTS1 FASTKD5 ECE1 SLAMF1 PLAG1 QSER1	3.49e-05	199	162	8	M8028
Coexpression	GSE14350_TREG_VS_TEFF_UP	CCDC186 MTERF3 CLOCK SLAMF1 MSL2 ASXL2 PRKDC MBD5	3.49e-05	199	162	8	M3417
Coexpression	GSE16385_IFNG_TNF_VS_UNSTIM_MACROPHAGE_ROSIGLITAZONE_TREATED_DN	KIAA0232 SLAMF1 PASK INTS6 ATP8A1 MTUS1 RAB3GAP2 PLAG1	3.62e-05	200	162	8	M8032
Coexpression	GSE28237_FOLLICULAR_VS_EARLY_GC_BCELL_UP	SLAMF8 ANKFY1 MTERF3 TRMT1 NFE2L2 OSBPL7 MARF1 MBD5	3.62e-05	200	162	8	M4884
ToppCell	TCGA-Pancreas-Primary_Tumor-Pancreatic_Adenocarcinoma-Ductal_Adenocarcinoma-1\|TCGA-Pancreas / Sample_Type by Project: Shred V9	NBEAL1 ZNF184 HEATR5A LGR5 BRWD3 CCSER2 MARF1 OSBPL11 ASXL2 GP5	1.72e-09	186	162	10	03db813598b67b1e08f759758a1c2023396921fa
ToppCell	COVID-19_Mild-Neu_3\|World / 5 Neutrophil clusters in COVID-19 patients	CARMIL2 LRTM1 TOGARAM2 CCDC168 CSMD3 GLI3 CSMD1	3.26e-07	122	162	7	2aa9cfadab70312882ae679e3788fc7ab996c0f3
ToppCell	droplet-Heart-HEART_(ALL_MINUS_AORTA)-30m-Neuronal-nan\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	L1CAM SLAMF1 F5 ATP8A1 RASGEF1C CSMD1 GP1BA GP5	3.88e-07	184	162	8	e33bb572af9dfd11127105f1ac99bc958a7cafbb
ToppCell	TCGA-Prostate-Primary_Tumor-Prostate_Adenocarcinoma-Acinar_Adenocarcinoma-6\|TCGA-Prostate / Sample_Type by Project: Shred V9	MAN2A1 NBEAL1 HEATR5A CLOCK DENND4C USF3 ASXL2 PRKDC	5.57e-07	193	162	8	abd71b2cf667ef2b1c4d88acd0c1dd19a12ff659
ToppCell	droplet-Pancreas-Exocrine-18m-Hematologic-leukocyte\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLAMF8 SLC7A13 CDHR3 TGM1 ADAMTSL5 NLRC5 CD180	9.11e-07	142	162	7	bf4a9633d128805a0d7e426d6fe6c29db1ff8c81
ToppCell	droplet-Pancreas-Exocrine-18m-Hematologic\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLAMF8 SLC7A13 CDHR3 TGM1 ADAMTSL5 NLRC5 CD180	1.15e-06	147	162	7	684e2d8d2f0516cf8b0dc53efa7efc3050bbf0d1
ToppCell	droplet-Pancreas-Exocrine-18m-Hematologic-leukocyte\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLAMF8 SLC7A13 CDHR3 TGM1 ADAMTSL5 NLRC5 CD180	1.15e-06	147	162	7	c031fad0a4e192019775809968e46da54a111d27
ToppCell	droplet-Lung-18m-Hematologic-lymphocytic-CD8-positive,_alpha-beta_T_cell-CD8-positive,_alpha-beta_T_cell_l21\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	PODNL1 CARMIL2 SIDT1 ZMYM2 SLAMF1 FAAH KNL1	1.26e-06	149	162	7	65778f19599b4955c0a16f0121237656449431fb
ToppCell	COVID-19_Moderate-multiplets\|World / disease group, cell group and cell class	SLAMF8 TOGARAM2 GPRIN3 ATP8A1 ADAMTSL5 OSBPL3 NLRC5	1.71e-06	156	162	7	afdc025fa75e7926b1cc182c4a33654a2186abb1
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	PCDHB2 CCDC168 F5 ZFPM2 NOP9 TENM3 ADAMTSL5	1.86e-06	158	162	7	e7db0ee4740e3c7a4d97d7cd7462e2c2ab458a4b
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell-Parietal_Epithelial_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	PCDHB2 CCDC168 F5 ZFPM2 NOP9 TENM3 ADAMTSL5	1.86e-06	158	162	7	d39e020c3e77eb9d3de600a171d22f94357061d4
ToppCell	facs-Lung-nan-3m-Epithelial-type_I_pneumocyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LRRC8E SLC7A13 NUDT12 NKX2-1 SORCS2 ERC2 PRKDC	2.59e-06	166	162	7	11b0ae82b3068ef91715dbdd49fe8e9791b4a480
ToppCell	droplet-Lung-3m-Hematologic-myeloid-classical_monocyte-classical_monocyte_l2-17-52\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	SLAMF8 FASTKD5 SIX4 F5 NOP9 FUT4 MX1	2.59e-06	166	162	7	de319c960b0cd90b294f677d1ea1b013a2ce2d53
ToppCell	facs-Lung-nan-3m-Epithelial-Alveolar_Epithelial_Type_1\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LRRC8E SLC7A13 NUDT12 NKX2-1 SORCS2 ERC2 PRKDC	2.59e-06	166	162	7	fcc1aec31ebd39432d4cb284dc8fadf34e3c566a
ToppCell	facs-Lung-18m-Hematologic-lymphocytic-CD8-positive,_alpha-beta_T_cell-CD8-positive,_alpha-beta_T_cell_l21\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	PODNL1 CARMIL2 SIDT1 IGFLR1 SLAMF1 OSBPL3 TONSL	2.80e-06	168	162	7	6c758eb120faf06ff72d157b495e399191c79ec9
ToppCell	Adult-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)-D231\|Adult / Lineage, Cell type, age group and donor	FRAS1 SIX4 ATP8A1 MTUS1 NKX2-1 TOX3 SORCS2	3.03e-06	170	162	7	269dee5abca9f6aa079f116f0d8f1d198604d9d4
ToppCell	facs-Lung-ENDOMUCIN-18m-Lymphocytic-CD8-positive,_alpha-beta_T_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PODNL1 CARMIL2 SIDT1 IGFLR1 SLAMF1 MIP TONSL	3.67e-06	175	162	7	a72c6ceca5ddbd34f652e7302defefa2d105e17e
ToppCell	facs-Lung-ENDOMUCIN-18m-Lymphocytic-CD8+_T\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PODNL1 CARMIL2 SIDT1 IGFLR1 SLAMF1 MIP TONSL	3.67e-06	175	162	7	9a462e9e6f7bbb64abb09ad6c080df3576073540
ToppCell	droplet-Heart-HEART_(LV+RV_ONLY)-30m-Neuronal-cardiac_neuron\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	L1CAM SIDT1 SLAMF1 F5 TONSL RASGEF1C GP5	4.92e-06	183	162	7	876b4f128c2168fdae7488201ff44f19c06c8415
ToppCell	droplet-Heart-HEART_(LV+RV_ONLY)-30m-Neuronal\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	L1CAM SIDT1 SLAMF1 F5 TONSL RASGEF1C GP5	4.92e-06	183	162	7	b190b650e61b1b20baf5e42d04acac82d3fd1400
ToppCell	-Unknown-Endothelial-Myofibroblast\| / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	USP24 ZMYM2 CLOCK PREPL ZFPM2 MTUS1 NOTCH2	5.87e-06	188	162	7	6468fa95ad0395395301115286f2d8c0df5d3882
ToppCell	-Unknown-Endothelial\| / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	USP24 ZMYM2 CLOCK PREPL ZFPM2 MTUS1 NOTCH2	5.87e-06	188	162	7	7a81ac5c79c3eb26639b52d2b9fd5e7ef9798fd6
ToppCell	-Unknown\| / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	USP24 ZMYM2 CLOCK PREPL ZFPM2 MTUS1 NOTCH2	5.87e-06	188	162	7	9cb718bfe1358c6fd842f096e228eb0abb9aefc6
ToppCell	356C-Lymphocytic-CD4_T-cell-Treg_cell_3\|CD4_T-cell / Donor, Lineage, Cell class and subclass (all cells)	CLOCK F5 ARG2 USF3 NKX2-1 IFRD2 ABLIM2	6.08e-06	189	162	7	99b01893da9f9f7c9528afaffad178285211738b
ToppCell	droplet-Pancreas-Endocrine-21m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KIAA0232 UBR4 ECE1 DENND4C DST ATP8A1 FAM151A	6.97e-06	193	162	7	fe451b3295d77b2bd1ac25cf29310c85835a45fe
ToppCell	LPS-IL1RA+antiTNF-Epithelial_alveolar-AT_2-Differentiating_AT1\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	GPRIN3 ATP8A1 MTUS1 NKX2-1 OSBPL3 USP54	8.19e-06	130	162	6	6434d9106ccb38786dad36fab80163dfc07b6eb7
ToppCell	Neuronal\|World / cells hierarchy compared to all cells using T-Statistic	CSMD3 PREPL MAN1A2 ERC2 HERC1 CSMD1 ABLIM2	8.79e-06	200	162	7	48d801219bc771d6c7e151dc88ca4c179988de85
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Cortical_Collecting_Duct_Principal_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	L1CAM HSFY1 MTUS1 TOX3 SORCS2 GP5	1.65e-05	147	162	6	64fa0753a3a79f492ef8acc6942bf90d379a983f
ToppCell	COVID-19_Moderate-multiplets\|COVID-19_Moderate / disease group, cell group and cell class	SLAMF8 TOGARAM2 GPRIN3 TGM5 ADAMTSL5 ERC2	1.65e-05	147	162	6	baf15c773d7751bc6f64d4974a22738626f2b3ff
ToppCell	COVID-19_Mild\|World / 5 Neutrophil clusters in COVID-19 patients	CCDC168 SIX4 USF3 OSBPL3 MARF1 CSMD1	2.00e-05	152	162	6	2ff0980dfd8d430cca14649151d856edef115720
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen-high_Fibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	L1CAM TOGARAM2 LGR5 ZFPM2 GLI2 GLI3	2.57e-05	159	162	6	330ecbba97d47bc818a5e8d1d84b05d056bd831e
ToppCell	BAL-Mild-Myeloid-cDC-cDC-cDC_0\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	SIGLEC12 MYO10 TGM1 CDC42EP2 ERC2 LRRC73	2.57e-05	159	162	6	2f6c60ddff2208a68146f9786143d9aefd528840
ToppCell	BAL-Mild-Myeloid-cDC-cDC-cDC_0\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	SIGLEC12 MYO10 TGM1 CDC42EP2 ERC2 LRRC73	2.57e-05	159	162	6	ded4e3626a62fb6334403b7213b467fb7e8131c3
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen-high_Fibroblast-\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	L1CAM TOGARAM2 LGR5 ZFPM2 GLI2 GLI3	2.57e-05	159	162	6	cbb331eb689d8cea9e1146ba85e0a05d23301c47
ToppCell	367C-Lymphocytic-NK_cells-NK_cell_B1\|367C / Donor, Lineage, Cell class and subclass (all cells)	ANKFY1 FASTKD5 NLRC5 ASXL2 USP54 OAZ3	2.76e-05	161	162	6	f470b662566131dfe69a2fd01186ac8491196396
ToppCell	BAL-Mild-cDC_0\|Mild / Compartment, Disease Groups and Clusters	SIGLEC12 MYO10 ARG2 CDC42EP2 ERC2 LRRC73	2.96e-05	163	162	6	7047d3ba847930f42a6d5f71e18d49f3071c6409
ToppCell	PBMC_fresh-frozen-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c07-AHNAK\|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)	FAM161B SLAMF1 TGM5 ASXL2 ZRANB1 GP5	3.87e-05	171	162	6	7b0783d25055e5ea5b2fc44ebcb16bfd0adbcf81
ToppCell	facs-Heart-RV-18m\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLAMF1 CNTROB FAAH ARG2 PASK TGM1	4.00e-05	172	162	6	a26a73c41e5a05c9dd47a99f3320295f684c5e54
ToppCell	droplet-Lung-LUNG-30m-Lymphocytic-regulatory_T_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PODNL1 CARMIL2 GPRIN3 IGFLR1 SLAMF1 FAAH	4.00e-05	172	162	6	4d04df9776394ea156ed5822f92ae74fdefbaa3d
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	TOGARAM2 F5 ZFPM2 DST TENM3 ABLIM2	4.00e-05	172	162	6	6c17a1e586a72d1bd80c20c06370429c61dc9f85
ToppCell	droplet-Lung-LUNG-30m-Lymphocytic-Regulatory_T\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PODNL1 CARMIL2 GPRIN3 IGFLR1 SLAMF1 FAAH	4.00e-05	172	162	6	3acf35b774ebc0f9e96299d0bd3e9d03bbf6b90c
ToppCell	COVID-19_Mild-PLT_2\|COVID-19_Mild / Disease Group and Platelet Clusters	SLAMF8 CDHR3 FAM161B F5 NOP9 ASXL2	4.13e-05	173	162	6	d11705e56b6b21eec963ea224717f27680c781ed
ToppCell	facs-Pancreas-Exocrine-3m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FRAS1 DENND4C FAM151A HERC1 OAZ3 TBL2	4.26e-05	174	162	6	f1fe1f4216748a9562dd03bd48c70b23c7ff4d1d
ToppCell	ASK428-Immune-B_cell\|Immune / Donor, Lineage and Cell class of Lung cells from Dropseq	DBF4B NUDT12 CLCN3 CDC42EP2 USP54 CSMD1	4.40e-05	175	162	6	e0979e5795a49b4e5c9b88e7fe6b7bda7a413a6c
ToppCell	Adult-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)-D122\|Adult / Lineage, Cell type, age group and donor	ATP8A1 MTUS1 NKX2-1 TOX3 SORCS2 USP54	4.54e-05	176	162	6	3fee8a367bb9755aca1b7fcc968b08e51b6e9436
ToppCell	facs-Marrow-T_cells-18m-Lymphocytic-BM_CD8_+_CD4_T_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PODNL1 SIDT1 GPRIN3 IGFLR1 NLRC5 DOP1B	4.69e-05	177	162	6	6d86b2f97426b552dff5ce6ddf0ead1285ed618e
ToppCell	facs-Marrow-T_cells-18m-Lymphocytic-mature_alpha-beta_T_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PODNL1 SIDT1 GPRIN3 IGFLR1 NLRC5 DOP1B	4.69e-05	177	162	6	d8b1bbc224d062a57a6ad40b4b2af5d6e0fe63b3
ToppCell	TCGA-Brain-Primary_Tumor-Low_Grade_Glioma\|TCGA-Brain / Sample_Type by Project: Shred V9	CSMD3 DST CCSER2 MARF1 USP54 HERC1	4.69e-05	177	162	6	e8ab340b20cd41554c3841fe980e078e878af35f
ToppCell	droplet-Limb_Muscle-nan-24m-Endothelial-unknown\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CSMD3 SLAMF1 F5 NEK4 RASGEF1C GP5	4.84e-05	178	162	6	f2002a5c4758d0af6c1880ca12f0af0d5e8888e4
ToppCell	356C-Lymphocytic-CD4_T-cell-Treg_cell_2\|356C / Donor, Lineage, Cell class and subclass (all cells)	FBF1 ZNF184 SLAMF1 F5 INTS2 TONSL	4.84e-05	178	162	6	8b939659f713eea50a1a6e28b571f680ca0b4c12
ToppCell	facs-Pancreas-Exocrine-3m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FRAS1 PREPL DENND4C DST FAM151A HERC1	4.84e-05	178	162	6	fcbbcc44271515de1969b4732b6441c012693d5f
ToppCell	facs\|World / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLC39A1 ECE1 LGR5 TGM5 NHSL1 MARF1	4.99e-05	179	162	6	8001db3044e8657980e24422377c4fdb0d7b323e
ToppCell	356C-Lymphocytic-CD4_T-cell-Treg_cell_3\|356C / Donor, Lineage, Cell class and subclass (all cells)	SLAMF1 F5 ARG2 USF3 IFRD2 ABLIM2	4.99e-05	179	162	6	f378307eb20f002450c748b7be2289d6db2fcbcb
ToppCell	droplet-Heart-HEART_(ALL_MINUS_AORTA)-30m-Neuronal-cardiac_neuron\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	L1CAM SLAMF1 SORCS2 RASGEF1C CSMD1 GP1BA	5.15e-05	180	162	6	d9c9399df3e2d9f23dbbfffb6cbe8404bf01e2b7
ToppCell	droplet-Heart-HEART_(ALL_MINUS_AORTA)-30m-Neuronal\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	L1CAM SLAMF1 SORCS2 RASGEF1C CSMD1 GP1BA	5.15e-05	180	162	6	dad458398683ff80a6e207bdc08e257d1bb757d6
ToppCell	droplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_D_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PPFIA2 LRTM1 CSMD3 F5 LINGO1 SORCS2	5.15e-05	180	162	6	8bf6e8b6b45ce42f8c5f23e7cd1752ec8b3fa2d2
ToppCell	facs-Pancreas-Endocrine-24m-Epithelial-pancreatic_D_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SIDT1 PCDHB2 ECE1 F5 LINGO1 NRXN2	5.15e-05	180	162	6	0677bf4a5177d9cbc6716195bd966eeae8de2f31
ToppCell	TCGA-Colorectal-Primary_Tumor-Colorectal_Adenocarcinoma-Colon_Adenocarcinoma-5\|TCGA-Colorectal / Sample_Type by Project: Shred V9	SIDT1 ADNP2 ATP8A1 CLCN3 FUT4 DOP1B	5.31e-05	181	162	6	8fcc9e77fee7c248df26b6c59b10e672242e2084
ToppCell	356C-Lymphocytic-CD4_T-cell-Treg_cell_2\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	ZNF184 SLAMF1 F5 INTS2 NKX2-1 TONSL	5.64e-05	183	162	6	f142b320023eef00b48d4820c46214c9794d37e7
ToppCell	Primary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L2-4_PVALB_C8orf4\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	TRPC5 TOGARAM2 ASB13 TENM3 MTUS1 TOX3	5.64e-05	183	162	6	04d3cc76038b8192c915f1c08c3e26f2ad3b3779
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_2\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	FRAS1 USP24 NFE2L2 OSBPL3 TOX3 GP1BA	5.64e-05	183	162	6	2e831a4d99c6f983793df71c0994124c943c6da9
ToppCell	Adult-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)\|Adult / Lineage, Cell type, age group and donor	ATP8A1 MTUS1 NKX2-1 TOX3 SORCS2 USP54	5.99e-05	185	162	6	673f0c688ae6984bc8027df2da335787924f4137
ToppCell	Children_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)\|Children_(3_yrs) / Lineage, Cell type, age group and donor	ATP8A1 MTUS1 NKX2-1 TOX3 SORCS2 USP54	5.99e-05	185	162	6	98b8ee42b89d97e4c9db01740e0c193503c68f2c
ToppCell	wk_15-18-Epithelial-Distal_epithelial_progenitor-epi-tip_intermediate\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	FRAS1 LGR5 NHSL1 NOP9 MTUS1 IL17RD	5.99e-05	185	162	6	636505a3d96f75d951ab42bcf8af6ae07abc732d
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	TOGARAM2 F5 ZFPM2 DST TENM3 ABLIM2	5.99e-05	185	162	6	b848b63aff4d9dbb9e66a85876d4c7c6dacd0579
ToppCell	356C-Lymphocytic-CD4_T-cell-Treg_cell_3\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	CLOCK F5 ARG2 NKX2-1 IFRD2 ABLIM2	6.36e-05	187	162	6	c8278525b3e1d3f3f4defcaf109cce22dd2e157a
ToppCell	Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)\|World / Lineage, Cell type, age group and donor	ATP8A1 MTUS1 NKX2-1 TOX3 SORCS2 USP54	6.36e-05	187	162	6	81cc8435b2704a9a8287b3f54acaae0f11dd4ac7
ToppCell	LPS-antiTNF-Epithelial_alveolar-AT_1-Differentiating_AT2\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	FRAS1 ATP8A1 MTUS1 OSBPL3 SORCS2 USP54	6.36e-05	187	162	6	58d48128547ee3513d0bf7f78e61b76b1c472ca9
ToppCell	TCGA-Breast-Primary_Tumor-Breast_Carcinoma-Infiltrating_Lobular_Carcinoma-6\|TCGA-Breast / Sample_Type by Project: Shred V9	ADGRA2 NRXN2 GLI2 SIGLEC6 TNN SORCS2	6.55e-05	188	162	6	c90669b51e1902fe7726555290c91c92a911df83
ToppCell	3'-Adult-LargeIntestine-Hematopoietic-Myeloid-cDC2\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SLAMF8 SIGLEC12 TGM5 SIGLEC6 ERC2 CD180	6.74e-05	189	162	6	8419d62e6991851bdc6ad861f5c9086ff808b222
ToppCell	Fetal_29-31_weeks-Mesenchymal-matrix_fibroblast_1_cell-D150\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	FRAS1 MYO10 CSMD3 IGSF10 DST GLI3	6.74e-05	189	162	6	203c80030df08ae112f9ae4043709f455d87ce89
ToppCell	10x_3'_v2v3-Neoplastic-Stem-like-NPC-like-NPC-like_neural-B\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	L1CAM PCDHB4 LINGO1 NRXN2 NKX2-1 TOX3	6.74e-05	189	162	6	8e6b6025f5554672e26a5d19fe365acb4333789c
ToppCell	droplet-Heart-nan-18m-Neuronal-cardiac_neuron\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	EVC2 L1CAM FAM161B FAAH SORCS2 CSMD1	6.74e-05	189	162	6	0493f7b79127c207fd7ade778ef4810500495d7e
ToppCell	renal_medulla_nuclei-Adult_normal_reference\|renal_medulla_nuclei / Celltypes from Cells and Nuclei per compartment and clinical group	MYO10 ARG2 MTUS1 OSBPL3 SORCS2 MBD5	6.94e-05	190	162	6	f1363f7806cfc4f14fbc1b0e8dac2de813a88eee
ToppCell	Somatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	TRPC5 TOGARAM2 TENM3 MTUS1 OSBPL3 TOX3	6.94e-05	190	162	6	3f22c118d552345f731d4d49f0bcb5765d93de3b
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	TRPC5 TOGARAM2 TENM3 MTUS1 OSBPL3 TOX3	6.94e-05	190	162	6	305fbef734c350cfbf786ca7ff6e07093aab56ea
ToppCell	facs-Pancreas-Endocrine-3m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PREPL DENND4C DST TENM3 FAM151A ERC2	7.35e-05	192	162	6	5b7093d5af5ae7b0e6d3a464cc56272440ecedad
ToppCell	343B-Lymphocytic-ILC-ILC-1\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	HEATR5A PABIR2 USF3 MTUS1 RAB3GAP2 ASXL2	7.35e-05	192	162	6	445985fe1bcd33e4f0a1704b27988fbfc9334538
ToppCell	primary_visual_cortex-Neuronal-GABAergic_neuron-Pvalb-Pvalb_Vipr2\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	FRAS1 ADAMTSL5 NKX2-1 TOX3 SOHLH1	7.46e-05	119	162	5	6425425b2e622c97b6c74c530ccbfe394d3b202d
ToppCell	facs-Brain_Myeloid-Hippocampus-3m-Myeloid\|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLC39A1 USP24 CHD9 MAN1A2 DST OSBPL11	7.57e-05	193	162	6	06b65110db974f4ef90d3511ff34428976a52c9c
ToppCell	facs-Brain_Non-Myeloid-Cortex-24m-Neuronal\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	L1CAM SIDT1 LINGO1 NRXN2 ERC2 CSMD1	7.57e-05	193	162	6	be28070c049e7cb68bcd54f582226eb2f5e4bc1c
ToppCell	facs-Brain_Myeloid-Hippocampus-3m-Myeloid-microglial_cell\|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLC39A1 USP24 CHD9 MAN1A2 DST OSBPL11	7.57e-05	193	162	6	9c16032bc03df8760ae199e8f19fdafa4c3f1827
ToppCell	droplet-Pancreas-Endocrine-21m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KIAA0232 UBR4 DENND4C DST ATP8A1 FAM151A	7.57e-05	193	162	6	471e65f02937bc18d7c5facdacdf1df58cf0f839
ToppCell	facs-Brain_Myeloid-Hippocampus-3m\|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLC39A1 USP24 CHD9 MAN1A2 DST OSBPL11	7.57e-05	193	162	6	a4f91bca5eaa985982d33a528f7566ffde154d47
ToppCell	facs-Brain_Non-Myeloid-Cortex-24m-Neuronal-nan\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	L1CAM SIDT1 LINGO1 NRXN2 ERC2 CSMD1	7.57e-05	193	162	6	0c652ebe22ce5d2927599dd97ef1920547858395
ToppCell	facs-Brain_Non-Myeloid-Cortex-24m-Neuronal-neuron\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	L1CAM SIDT1 LINGO1 NRXN2 ERC2 CSMD1	7.57e-05	193	162	6	8689a70a33a7c3823dc647d41ac0160e7c3ae396
ToppCell	facs-Brain_Myeloid-Hippocampus-3m-Myeloid-nan\|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLC39A1 USP24 CHD9 MAN1A2 DST OSBPL11	7.57e-05	193	162	6	b39d7feaac4ff8f7409cd3d15e8f3c6391367275
ToppCell	frontal_cortex-Neuronal-GABAergic_neuron-Lamp5-Lamp5_Lhx6\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	TRPC5 TOGARAM2 TENM3 NKX2-1 TOX3	7.77e-05	120	162	5	a4e3f9a83bc52ccc75bcd64b1be4e2c5441f6d1a
ToppCell	Fetal_29-31_weeks-Mesenchymal-matrix_fibroblast_1_cell-D062\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	FRAS1 MYO10 ZFPM2 DST GLI2 GLI3	7.79e-05	194	162	6	35f132cc38ac133be01834ed0946188aa0757eb4
ToppCell	droplet-Pancreas-Endocrine-21m-Epithelial\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	UBR4 ECE1 DENND4C DST ATP8A1 FAM151A	7.79e-05	194	162	6	0b023de48ed8a550d169bbe954881eb04bf4f981
ToppCell	facs-Skin-Telogen-3m-Epithelial-bulge_keratinocyte\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LGR5 TGM5 IGSF10 DST MTUS1 USP54	8.24e-05	196	162	6	90edf61116ffcb4f8b6be3d0a05732d59b0a87d5
ToppCell	facs-Skin-Telogen-3m-Epithelial-outer_bulge\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LGR5 TGM5 IGSF10 DST MTUS1 USP54	8.24e-05	196	162	6	c936014125b2ed5f796221b74acb77b8f8359875
ToppCell	343B-Myeloid-Macrophage-FABP4+_Macrophage\|Macrophage / Donor, Lineage, Cell class and subclass (all cells)	CARMIL2 MYO10 LRTM1 F5 PREPL	8.40e-05	122	162	5	a2f343962069253a08faa80fd70723b8488a99ec
ToppCell	Bronchial-NucSeq-Stromal-Schwann-Schwann_nonmyelinating\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	L1CAM PCDHB4 BPIFA1 LGR5 TENM3 RASGEF1C	8.47e-05	197	162	6	4a7ff67bb0754e034e6f2a1bd34cde86ee3ef899
ToppCell	PCW_13-14-Mesenchymal-Mesenchymal_fibroblastic-mes_immature1_(0)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	FRAS1 MYO10 CSMD3 IGSF10 DST GLI3	8.47e-05	197	162	6	0034bae02ee7fcfea520d453ca3c842ab6963b12
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Neuronal\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	PPFIA2 CSMD3 PREPL ERC2 HERC1 CSMD1	8.71e-05	198	162	6	0ff30edfd3c133a42e8cb96e1631a1143215f808
ToppCell	Bronchial-NucSeq-Immune_Lymphocytic-T-T_CD4-T_reg\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	CDHR3 SIDT1 GPRIN3 SLAMF1 F5 NLRC5	8.71e-05	198	162	6	7608f67959e1cda7b10e57fd3af2f96216ebe7e9
ToppCell	Sigmoid-T_cell-Tfh\|Sigmoid / Region, Cell class and subclass	SLC39A1 GPRIN3 PASK CCSER2 NLRC5 ZNF121	8.96e-05	199	162	6	fa9404a021a015d1d571c324780b6eef2da47c4c
ToppCell	Sigmoid-(1)_T_cell-(16)_Tfh\|Sigmoid / shred on region, Cell_type, and subtype	SLC39A1 GPRIN3 PASK CCSER2 NLRC5 ZNF121	8.96e-05	199	162	6	a61bf52d2d359746433623ee00337124f1f84f61
ToppCell	LPS_IL1RA_TNF-Epithelial_alveolar-AT_1-Differentiating_AT2\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	LRTM1 FAAH MAN1A2 ATP8A1 MTUS1 USP54	8.96e-05	199	162	6	121de4e02585de3a3010398387c523bacf8ce546
Drug	Norgestrel-(-)-D [797-63-7]; Up 200; 12.8uM; PC3; HT_HG-U133A	UBR4 ADGRA2 F5 GLI2 RAB3GAP2 ERC2 FUT4 POU2F3 TBL2	1.04e-05	193	162	9	3708_UP
Drug	Thioguanosine [85-31-4]; Down 200; 12.6uM; HL60; HT_HG-U133A	PEX1 ASB13 MAN1A2 CLCN3 OSBPL3 RAB3GAP2 OSGIN2 TBCE DOP1B	1.08e-05	194	162	9	1264_DN
Drug	(d,l)-Tetrahydroberberine [522-97-4]; Down 200; 11.8uM; HL60; HT_HG-U133A	CCDC186 F5 MAN1A2 MTUS1 GLI3 CCSER2 TBL2 MX1 DOP1B	1.13e-05	195	162	9	2163_DN
Drug	N-Acetyl-DL-homocysteine Thiolactone [1195-16-0]; Down 200; 25.2uM; PC3; HT_HG-U133A	ANKFY1 SLC39A1 CCDC186 ZMYM2 REST PASK MTUS1 SNAPC4 FUT4	1.13e-05	195	162	9	3755_DN
Disease	non-arteritic anterior ischemic optic neuropathy (is_implicated_in)	F5 GP1BA	2.64e-04	5	153	2	DOID:0050864 (is_implicated_in)
Disease	MASA syndrome (implicated_via_orthology)	L1CAM TRPM1	5.51e-04	7	153	2	DOID:0060246 (implicated_via_orthology)
Disease	severe acute respiratory syndrome, COVID-19	HAUS7 LRTM1 ZFPM2 GLI2 TOX3 SORCS2 OSBPL11 TRPM1 CSMD1	5.66e-04	447	153	9	EFO_0000694, MONDO_0100096
Disease	blood urea nitrogen measurement	PPFIA2 DLEU1 TRMT1 CHD9 GPRIN3 MIP ASXL2 MBD5 ZRANB1	6.13e-04	452	153	9	EFO_0004741
Disease	sialic acid-binding Ig-like lectin 6 measurement	SIGLEC12 SIGLEC6	7.33e-04	8	153	2	EFO_0008285
Disease	primary bacterial infectious disease (implicated_via_orthology)	GLI2 GLI3	9.39e-04	9	153	2	DOID:0050338 (implicated_via_orthology)
Disease	S-6-hydroxywarfarin to S-warfarin ratio measurement	MAN2A1 CSMD3 ZFPM2 ABLIM2	1.16e-03	88	153	4	EFO_0803332
Disease	cognitive function measurement	ANKFY1 MAN2A1 DBF4B EEF1E1 PPFIA2 ZNF184 FAM161B BPIFA1 CSMD3 ADGRA2 ZFPM2 LINGO1 GLI3 ERC2 ASXL2 ABLIM2 TBCE	1.28e-03	1434	153	17	EFO_0008354
Disease	Thrombus	F5 FUT4 GP1BA	1.76e-03	46	153	3	C0087086
Disease	disease progression measurement, Crohn's disease	CDHR3 SORCS2 CSMD1	1.88e-03	47	153	3	EFO_0000384, EFO_0008336
Disease	neurotic disorder	ZNF184 LINGO1 TENM3 CSMD1	1.92e-03	101	153	4	EFO_0004257
Disease	Thrombosis	F5 FUT4 GP1BA	2.11e-03	49	153	3	C0040053
Disease	neuroticism measurement	NBEAL1 PPFIA2 ZNF184 ECE1 MSL2 LINGO1 TENM3 TOX3 SORCS2 HERC1 CSMD1 MBD5	2.85e-03	909	153	12	EFO_0007660
Disease	interferon gamma measurement, platelet-derived growth factor BB measurement, interleukin 4 measurement, interleukin 10 measurement, stromal cell-derived factor 1 alpha measurement, interleukin-6 measurement, interleukin 12 measurement, interleukin 17 measurement, vascular endothelial growth factor measurement, fibroblast growth factor basic measurement, granulocyte colony-stimulating factor measurement	F5 ZFPM2	3.06e-03	16	153	2	EFO_0004750, EFO_0004753, EFO_0004762, EFO_0004810, EFO_0008130, EFO_0008142, EFO_0008165, EFO_0008174, EFO_0008184, EFO_0008264, EFO_0008293
Disease	response to triptolide, cytotoxicity measurement	ADGRA2 CSMD1	3.06e-03	16	153	2	EFO_0006952, EFO_0007662
Disease	Polydactyly	FRAS1 EVC2 GLI2 GLI3	3.27e-03	117	153	4	C0152427
Disease	triacylglycerol 48:1 measurement	ERC2 CSMD1	3.45e-03	17	153	2	EFO_0010404
Disease	Fetal Alcohol Syndrome	REST BPIFA1	3.45e-03	17	153	2	C0015923
Disease	ferritin measurement	TOGARAM2 F5 TENM3 GNL3	3.48e-03	119	153	4	EFO_0004459
Disease	prostate carcinoma, type 2 diabetes mellitus	SIDT1 OSBPL7 KNL1	3.59e-03	59	153	3	EFO_0001663, MONDO_0005148
Disease	Malignant neoplasm of skin	NFE2L2 GLI2 NOTCH2	3.59e-03	59	153	3	C0007114
Disease	Skin Neoplasms	NFE2L2 GLI2 NOTCH2	3.59e-03	59	153	3	C0037286
Disease	Febrile seizure (within the age range of 3 months to 6 years)	ERC2 HERC1	3.87e-03	18	153	2	HP_0002373
Disease	acute kidney failure (biomarker_via_orthology)	ECE1 ARG2 NFE2L2	3.95e-03	61	153	3	DOID:3021 (biomarker_via_orthology)
Disease	triacylglycerol 46:1 measurement	ERC2 CSMD1	4.77e-03	20	153	2	EFO_0010401
Disease	sphingomyelin 22:0 measurement	DLEU1 CSMD1	4.77e-03	20	153	2	EFO_0010395
Disease	venous thromboembolism, fibrinogen measurement	CHD9 F5 ZFPM2	5.14e-03	67	153	3	EFO_0004286, EFO_0004623

Protein segments in the cluster

Peptide	Gene	Start	Entry
TSHPADNGLTLELSL	CCDC186	836	Q7Z3E2
NAITHLPLSIFASLG	CPN2	251	P22792
ADINTPLTTSSGNLH	ARG2	146	P78540
HQINSSGVLSLPELS	CENPQ	201	Q7L2Z9
SSGQSPLLVVLSGNH	CSMD1	2381	Q96PZ7
GTTIPHLLNSTSNNL	CSMD3	2011	Q7Z407
STLLPISHENLTGSA	CCDC62	651	Q6P9F0
PSALHAQALGSLQEA	ADGRA2	221	Q96PE1
STLTHLDLSGNPGAL	CARMIL2	336	Q6F5E8
DSITPLHAASLQGQA	ASB13	51	Q8WXK3
IQGINHLLSLDFASP	BRWD3	1151	Q6RI45
LPVSVGSSAHLSQGL	ABLIM2	136	Q6H8Q1
SHLQTLNLSHNEPLG	CD180	396	Q99467
FLDTSNQHLLAGLPV	CD180	456	Q99467
NGEHLPADLISLSSS	ATP8A1	161	Q9Y2Q0
SSALNTHELSSILPI	ASXL2	466	Q76L83
AQPGFIHNSELLLVS	ADNP2	951	Q6IQ32
LALNTLHPAVSVGQA	MIP	116	P30301
SPAALQGQVSSLSHL	NKX2-1	336	P43699
SNPSHLSLDLSGIDS	NBEAL1	1366	Q6ZS30
LLNSSGPLIEHSSGS	RAD21L1	176	Q9H4I0
NTTSNGILSHHDPLL	QSER1	86	Q2KHR3
TTSGVQDELHLPLNS	INTS6	136	Q9UL03
ATHLNGLQAPSETAL	INSYN2A	291	Q6ZSG2
PLASLVSINADNGHL	PCDHB2	501	Q9Y5E7
PLTSLVSINADNGHL	PCDHB18P	446	Q96TA0
LTSLENLEHPQSGSL	ANKRD31	1461	Q8N7Z5
NAATLGAQETPLHLV	ANKFY1	316	Q9P2R3
GSTQPLLSHVALAVA	RAB3GAP2	321	Q9H2M9
EAPGFSNTSLIILHQ	NUP133	586	Q8WUM0
AHGASTVLPSVSQLL	NOTCH2	2211	Q04721
LPGLAANINESTHIS	REST	906	Q13127
SLAQSPAGSHVLDAI	NOP9	516	Q86U38
LSQLSLAGALDVPHA	PASK	666	Q96RG2
ELDLSSNNISHLPTS	LRTM1	126	Q9HBL6
SAGNLTVLATDPLLH	OAZ3	101	Q9UMX2
NNLTTLHGELSSLPS	FLII	66	Q13045
SDTPHLAINQGLQLS	FRAS1	2076	Q86XX4
GALSPSIIQNLSHSS	GLI3	1521	P10071
HAFQVLSQGSLLESP	HSFY1	46	Q96LI6
ALDGSAALQPLLHTV	IL17RD	636	Q8NFM7
ELPESTHSTLLANGS	IGDCC3	81	Q8IVU1
QGAGSHLLPSQLSLS	MAN2A1	96	Q16706
LQALATLLSSPHGGA	INTS1	1406	Q8N201
LGTQNHTSELILSSP	MTUS1	386	Q9ULD2
LNSGFAQTLHPSLTS	DST	506	Q03001
SHSPGLRSLASNLFN	FUT4	301	P22083
LNPLTAHLGVQLTAA	DOP1B	1676	Q9Y3R5
SPNGNLFSSHLATLQ	ZFPM2	926	Q8WW38
LLGTSSSENSQPAHL	HERC1	971	Q15751
LPFSSALQGLSHLSL	DLEU1	21	O43261
ALQGLSHLSLGTTLP	DLEU1	26	O43261
ATLQHSLQLSLPGKS	NHSL1	706	Q5SYE7
PILDSTVLNSHLLAG	KIAA0232	616	Q92628
TTAGLLLSSQPNHGL	OPTC	111	Q9UBM4
LAHSNLRLLGSSDSP	NEK4	471	P51957
SPATLSHSLSELLNG	NFE2L2	301	Q16236
TSNLSANITGFLPIH	INTS2	541	Q9H0H0
SPLFSHILNSLQGLS	ABCC11	996	Q96J66
PAHLTLNSEVGSLLF	NRXN2	251	Q9P2S2
VLLAPSVQDSGSLHN	MYO10	1051	Q9HD67
TASDLLGNHSLGLPL	PDZD3	21	Q86UT5
LKNLTSSGHLSPQVE	EVC2	411	Q86UK5
TAGPLTNDLLHNLSG	LCT	31	P09848
SGLASLSANTLPVHI	FAM161B	441	Q96MY7
DLTFNHTLQILPATG	KNL1	346	Q8NG31
TNSSSHLVALQGQPL	L1CAM	246	P32004
HSVGNLETLILDSNP	LINGO1	356	Q96FE5
SGALSPSLLHSLSQN	GLI2	1526	P10070
TLLLGDNQLSQLSPH	LRRC8E	726	Q6NSJ5
SPNIASAGLSHTDVL	ERC2	101	O15083
GPFLQLSSQSLSHNV	MSL2	301	Q9HCI7
PGHLQSVSQFLLSQT	POU2F3	101	Q9UKI9
LQAAGPTSHDLLLQV	ADAMTSL5	281	Q6ZMM2
PISGLLDLSHNSISQ	NLRC5	1271	Q86WI3
APLIHGLSDLSQVFQ	PABIR2	26	Q7Z309
HLPLASLVSINADNG	PCDHB4	496	Q9Y5E5
LDLSHNQLTTVPAGL	PODNL1	271	Q6PEZ8
LSAAVVLIGSHPNLS	OSGIN2	406	Q9Y236
GSGSLHDIQLSLPSS	CCSER2	691	Q9H7U1
GLNLHIPTLSQSNTF	CHD9	2811	Q3L8U1
SQPLTSTQGLEHAAA	FBF1	461	Q8TES7
EQHPVLLGSTSFALL	FASTKD5	176	Q7L8L6
TNQHSSTVFPLLLGA	IGSF10	886	Q6WRI0
IHNLGTTAAPLLQDS	HEATR5A	426	Q86XA9
THSPGSLQISLLDGL	BPIFA1	181	Q9NP55
NASSLLSLHVDLGPS	CDC42EP2	176	O14613
FTQSHLVTSLALLPG	DBF4B	451	Q8NFT6
HTPSGNILTLESCLQ	FAM151A	386	Q8WW52
HLILLPATGNVAENS	CDHR3	21	Q6ZTQ4
AHLSPSTGVLLSNLV	GGT6	376	Q6P531
NLSLLLGIHSAQHPE	CEP85	701	Q6P2H3
PSASLGQLGTHLAQL	IGFLR1	321	Q9H665
HILGENISPNTSISG	DENND4C	1406	Q5VZ89
NEALLGELFSSPHLQ	HAUS7	161	Q99871
HSPLSLSIASGNELV	ANKMY1	696	Q9P2S6
GTLDLSHNQLQSLPL	GP1BA	96	P07359
TSSLIHPGALLDSQS	MARF1	126	Q9Y4F3
VPASLHGLLSAALQA	IFRD2	291	Q12894
GDPLNLSSAVSAVIH	MBD5	1131	Q9P267
VLHLANTTLSGNPAV	MAN1A2	626	O60476
PHLANSILFQSSGLT	GNL3	446	Q9BVP2
LQVLALHSNGLTALP	GP5	341	P40197
SNIPHALETLSTGGL	FAAH	366	O00519
AEHSLPTLGLTNNQL	ECE1	691	P42892
PAVALGSFNNHLLTL	CCDC168	1051	Q8NDH2
TPLAATHQSGSLALL	COX15	381	Q7KZN9
GSHTLELSDSTLAPQ	GPRIN3	366	Q6ZVF9
TSQSQQSLHPLLVSA	PEX1	711	O43933
DLSLLLGPSFQSQHS	CNTROB	636	Q8N137
DLLSPSGHSDAQTLA	PPFIA2	636	O75334
SNLLSSFPITGLHGL	LGR5	431	O75473
LHSSNPNLSTLDFGE	OSBPL3	301	Q9H4L5
GLPSSAEQQHLLSVL	OR1C1	16	Q15619
LPTSGHLSSLDQDLL	OSBPL11	241	Q9BXB4
PQLSQTSILSLADSH	OSBPL7	386	Q9BZF2
NNGPSLTGLTTIAAH	EEF1E1	36	O43324
TLLHGFSAQPQISSD	MTERF3	36	Q96E29
LPLSSLVSINADNGH	PCDHB6	496	Q9Y5E3
IGNANALPHTLLTAS	OR1A1	151	Q9P1Q5
SHLQGNLSLLSPNHS	OPRL1	16	P41146
ENSLLSCTLHTGTPN	RHNO1	176	Q9BSD3
ALGPSQEQHAILASS	SOHLH1	106	Q5JUK2
LSSTIHCNTPSLLQL	TRMT1	451	Q9NXH9
HASANSLPAVLTLGS	TOGARAM2	451	Q6ZUX3
HTTLSLDLSQTNLSP	F5	1246	P12259
PSHTTLSLDLSQTNL	F5	1361	P12259
GHSLQPLLSLDNSVT	SORCS2	911	Q96PQ0
SHLLSLTLGPQHADN	SLAMF1	191	Q13291
GSGLHPLASSLVNVS	SIX4	601	Q9UIU6
AQHPLGSLQISLSLF	SIGLEC6	321	O43699
ILSHSPSLLNETSEN	NUDT12	31	Q9BQG2
PLGSQHISLSLSLQN	SIGLEC12	451	Q96PQ1
TLGPQAHSLALQSVD	SSBP3-AS1	81	Q7Z2R9
LLHGNPSTQLILSAA	CLOCK	791	O15516
NGGSINSSTHLLDLL	CLCN3	61	P51790
PANTIGLGSLHSLSA	PLAG1	466	Q6DJT9
PNASLIGLTATATNH	RECQL	246	P46063
SPQHLLATTDLAVLG	TNN	341	Q9UQP3
QLILSDTGISSLHFP	TBCE	281	Q15813
AESAGPLHQLAQSVL	SLC39A1	261	Q9NY26
QSLPAGTLLHLELSS	TONSL	1211	Q96HA7
GAPSSASLETLIQHL	RASGEF1C	36	Q8N431
AHPLGVLSAFNNILS	SIDT1	486	Q9NXL6
GNVTSVLELSSNPAH	TENM3	1201	Q9P273
TLHGQGFSQPSLTTL	PREPL	541	Q4J6C6
QSLLAPHLSDQVIGS	USF3	1821	Q68DE3
GQLPLLFNTLNSHSS	SLC7A13	321	Q8TCU3
LLLNTPLSQHGTVSA	TOX3	356	O15405
QLHSNLSLELGPLES	SLAMF8	81	Q9P0V8
PHSLFTDGQVLSISL	SLAMF8	176	Q9P0V8
VNLSAQSLLHDGSPL	TGM5	541	O43548
AGLLHNILPSQSTDL	PRKDC	1461	P78527
LVPECQNSLHLSLGT	TRPM1	1316	Q7Z4N2
QLGSHSPVALLNTLF	ZMYM2	1206	Q9UBW7
LHNSAPAGETLSVLN	ZNF121	51	P58317
IILNSHSPAGSAAIS	USP24	1606	Q9UPU5
LLQASSSAQSTPGHL	SNAPC4	831	Q5SXM2
LIASLDSPQLSQVHG	TGM1	766	P22735
LFTANSHLGPLQISL	TRPC5	496	Q9UL62
QAAHLGTLCSQSLPL	UBR4	1266	Q5T4S7
PNAQVLALASGSSIH	TBL2	341	Q9Y4P3
LSLASQPGASLEQTH	ZRANB1	511	Q9UGI0
SPDSTLLQGGHNLLS	ZNF184	6	Q99676
ESTEHSSLALNSGLP	USP54	1201	Q70EL1
SIQSLFLHGSPLTDA	LRRC73	86	Q5JTD7
ASHPLLLNGDATVAQ	MX1	16	P20591