Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyBiologicalProcess	nuclear-transcribed mRNA poly(A) tail shortening	TNRC6B TNKS1BP1 SAMD4A TNRC6A	2.15e-07	33	33	4	GO:0000289
GeneOntologyBiologicalProcess	nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay	TNRC6B TNKS1BP1 SAMD4A TNRC6A	3.43e-06	65	33	4	GO:0000288
GeneOntologyBiologicalProcess	nuclear-transcribed mRNA catabolic process	TNRC6B TNKS1BP1 SAMD4A TNRC6A	5.68e-05	132	33	4	GO:0000956
GeneOntologyBiologicalProcess	mRNA metabolic process	RBM6 TNRC6B MFAP1 SCAF11 TNKS1BP1 RBM19 SAMD4A TNRC6A	7.62e-05	917	33	8	GO:0016071
GeneOntologyBiologicalProcess	positive regulation of nuclear-transcribed mRNA poly(A) tail shortening	TNRC6B TNRC6A	2.23e-04	14	33	2	GO:0060213
GeneOntologyBiologicalProcess	regulation of nuclear-transcribed mRNA poly(A) tail shortening	TNRC6B TNRC6A	2.94e-04	16	33	2	GO:0060211
GeneOntologyBiologicalProcess	mRNA destabilization	TNRC6B TNKS1BP1 SAMD4A TNRC6A	3.15e-04	206	33	4	GO:0061157
GeneOntologyBiologicalProcess	RNA destabilization	TNRC6B TNKS1BP1 SAMD4A TNRC6A	3.45e-04	211	33	4	GO:0050779
GeneOntologyBiologicalProcess	positive regulation of mRNA catabolic process	TNRC6B TNKS1BP1 SAMD4A TNRC6A	3.45e-04	211	33	4	GO:0061014
GeneOntologyBiologicalProcess	negative regulation of translation	TNRC6B SAMD4A CPEB4 TNRC6A	4.78e-04	230	33	4	GO:0017148
GeneOntologyBiologicalProcess	RNA catabolic process	TNRC6B TNKS1BP1 DEDD2 SAMD4A TNRC6A	5.76e-04	432	33	5	GO:0006401
GeneOntologyBiologicalProcess	positive regulation of mRNA metabolic process	TNRC6B TNKS1BP1 SAMD4A TNRC6A	7.46e-04	259	33	4	GO:1903313
GeneOntologyBiologicalProcess	nucleic acid catabolic process	TNRC6B TNKS1BP1 DEDD2 SAMD4A TNRC6A	7.95e-04	464	33	5	GO:0141188
GeneOntologyCellularComponent	P-body	TNRC6B SAMD4A TNRC6A	5.05e-04	102	32	3	GO:0000932
GeneOntologyCellularComponent	cytoplasmic ribonucleoprotein granule	TNRC6B MOV10L1 SAMD4A TNRC6A	7.26e-04	269	32	4	GO:0036464
GeneOntologyCellularComponent	ribonucleoprotein granule	TNRC6B MOV10L1 SAMD4A TNRC6A	9.24e-04	287	32	4	GO:0035770
MousePheno	impaired contractility of urinary bladder detrusor smooth muscle	CHRM3 SLC3A1	1.55e-05	4	23	2	MP:0000741
Domain	RRM	RBM6 TNRC6B RBM19 RBMS1 CPEB4 TNRC6A	2.27e-06	230	32	6	PS50102
Domain	-	RBM6 TNRC6B RBM19 RBMS1 CPEB4 TNRC6A	3.19e-06	244	32	6	3.30.70.330
Domain	Nucleotide-bd_a/b_plait	RBM6 TNRC6B RBM19 RBMS1 CPEB4 TNRC6A	4.39e-06	258	32	6	IPR012677
Domain	Ago_hook	TNRC6B TNRC6A	8.52e-06	3	32	2	PF10427
Domain	TNRC6-PABC_bdg	TNRC6B TNRC6A	8.52e-06	3	32	2	PF16608
Domain	TNRC6_PABC-bd	TNRC6B TNRC6A	8.52e-06	3	32	2	IPR032226
Domain	Argonaute_hook_dom	TNRC6B TNRC6A	8.52e-06	3	32	2	IPR019486
Domain	RRM	RBM6 RBM19 RBMS1 CPEB4 TNRC6A	3.15e-05	217	32	5	SM00360
Domain	RRM_dom	RBM6 RBM19 RBMS1 CPEB4 TNRC6A	3.91e-05	227	32	5	IPR000504
Domain	RRM_1	RBM19 RBMS1 CPEB4	5.32e-03	208	32	3	PF00076
Domain	UBA-like	TNRC6B TNRC6A	5.37e-03	64	32	2	IPR009060
Domain	SAM_1	ARAP2 SAMD4A	6.04e-03	68	32	2	PF00536
Domain	SAM	ARAP2 SAMD4A	9.93e-03	88	32	2	SM00454
Domain	SAM_DOMAIN	ARAP2 SAMD4A	1.15e-02	95	32	2	PS50105
Domain	SAM	ARAP2 SAMD4A	1.20e-02	97	32	2	IPR001660
Domain	-	ARAP2 SAMD4A	1.42e-02	106	32	2	1.10.150.50
Pathway	REACTOME_POST_TRANSCRIPTIONAL_SILENCING_BY_SMALL_RNAS	TNRC6B TNRC6A	3.80e-05	6	23	2	MM15083
Pathway	REACTOME_POST_TRANSCRIPTIONAL_SILENCING_BY_SMALL_RNAS	TNRC6B TNRC6A	5.32e-05	7	23	2	M46421
Pathway	REACTOME_REGULATION_OF_PTEN_MRNA_TRANSLATION	TNRC6B TNRC6A	9.10e-05	9	23	2	M27810
Pathway	REACTOME_REGULATION_OF_NPAS4_MRNA_TRANSLATION	TNRC6B TNRC6A	9.10e-05	9	23	2	M46436
Pathway	REACTOME_REGULATION_OF_CDH11_MRNA_TRANSLATION_BY_MICRORNAS	TNRC6B TNRC6A	1.14e-04	10	23	2	M48013
Pathway	REACTOME_REGULATION_OF_NPAS4_GENE_EXPRESSION	TNRC6B TNRC6A	1.96e-04	13	23	2	M46434
Pathway	REACTOME_REGULATION_OF_RUNX1_EXPRESSION_AND_ACTIVITY	TNRC6B TNRC6A	3.41e-04	17	23	2	M27788
Pathway	REACTOME_REGULATION_OF_MITF_M_DEPENDENT_GENES_INVOLVED_IN_APOPTOSIS	TNRC6B TNRC6A	4.28e-04	19	23	2	M48238
Pathway	REACTOME_TGFBR3_EXPRESSION	TNRC6B TNRC6A	9.38e-04	28	23	2	M48253
Pathway	REACTOME_REGULATION_OF_HOMOTYPIC_CELL_CELL_ADHESION	TNRC6B TNRC6A	1.23e-03	32	23	2	M48012
Pathway	REACTOME_REGULATION_OF_MECP2_EXPRESSION_AND_ACTIVITY	TNRC6B TNRC6A	1.23e-03	32	23	2	M27900
Pathway	REACTOME_TRANSCRIPTIONAL_REGULATION_BY_NPAS4	TNRC6B TNRC6A	1.38e-03	34	23	2	M46422
Pathway	REACTOME_GENE_SILENCING_BY_RNA	TNRC6B MOV10L1 TNRC6A	1.44e-03	139	23	3	M715
Pathway	REACTOME_ONCOGENE_INDUCED_SENESCENCE	TNRC6B TNRC6A	1.47e-03	35	23	2	M27190
Pathway	REACTOME_NR1H3_NR1H2_REGULATE_GENE_EXPRESSION_LINKED_TO_CHOLESTEROL_TRANSPORT_AND_EFFLUX	TNRC6B TNRC6A	1.64e-03	37	23	2	M29790
Pathway	REACTOME_TRANSCRIPTIONAL_REGULATION_BY_VENTX	TNRC6B TNRC6A	2.01e-03	41	23	2	M29748
Pathway	REACTOME_NR1H2_AND_NR1H3_MEDIATED_SIGNALING	TNRC6B TNRC6A	2.63e-03	47	23	2	M29777
Pathway	REACTOME_GENE_SILENCING_BY_RNA	TNRC6B TNRC6A	2.86e-03	49	23	2	MM14837
Pathway	REACTOME_SIGNALING_BY_TGFBR3	TNRC6B TNRC6A	2.86e-03	49	23	2	M48250
Pathway	REACTOME_ADHERENS_JUNCTIONS_INTERACTIONS	TNRC6B TNRC6A	3.98e-03	58	23	2	M11980
Pathway	REACTOME_CA2_PATHWAY	TNRC6B TNRC6A	4.54e-03	62	23	2	M27321
Pathway	REACTOME_G_ALPHA_Q_SIGNALLING_EVENTS	BRS3 GRP CHRM3	4.63e-03	210	23	3	MM15043
Pathway	REACTOME_TRANSCRIPTIONAL_REGULATION_BY_MECP2	TNRC6B TNRC6A	4.68e-03	63	23	2	M27862
Pathway	REACTOME_G_ALPHA_Q_SIGNALLING_EVENTS	BRS3 GRP CHRM3	5.08e-03	217	23	3	M18437
Pathway	WP_MRNA_PROCESSING	RBM6 RBM19 RBMS1 CPEB4	5.65e-03	451	23	4	MM15946
Pubmed	Role of GW182 protein in the cell.	TNRC6B TNRC6A	9.28e-07	2	34	2	29791863
Pubmed	Gawky is a component of cytoplasmic mRNA processing bodies required for early Drosophila development.	TNRC6B TNRC6A	2.78e-06	3	34	2	16880270
Pubmed	Impact of scaffolding protein TNRC6 paralogs on gene expression and splicing.	TNRC6B TNRC6A	2.78e-06	3	34	2	34108231
Pubmed	Expression of TNRC6 (GW182) Proteins Is Not Necessary for Gene Silencing by Fully Complementary RNA Duplexes.	TNRC6B TNRC6A	2.78e-06	3	34	2	31670606
Pubmed	Bombesin-like peptide receptor gene expression, regulation, and function in fetal murine lung.	BRS3 GRP	5.56e-06	4	34	2	12959933
Pubmed	Two PABPC1-binding sites in GW182 proteins promote miRNA-mediated gene silencing.	TNRC6B TNRC6A	5.56e-06	4	34	2	21063388
Pubmed	The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts.	RBM6 MFAP1 SCAF11 RBM19 RBMS1 CPEB4 TNRC6A	1.10e-05	807	34	7	22681889
Pubmed	Novel genetic loci identified for the pathophysiology of childhood obesity in the Hispanic population.	CHRM3 TCFL5 SNX29 MOV10L1 ARAP2 SAMD4A CPEB4	1.16e-05	814	34	7	23251661
Pubmed	The C-terminal domains of human TNRC6A, TNRC6B, and TNRC6C silence bound transcripts independently of Argonaute proteins.	TNRC6B TNRC6A	1.94e-05	7	34	2	19383768
Pubmed	Functional dissection of the human TNRC6 (GW182-related) family of proteins.	TNRC6B TNRC6A	1.94e-05	7	34	2	19470757
Pubmed	A genome-wide in situ hybridization map of RNA-binding proteins reveals anatomically restricted expression in the developing mouse brain.	RBM6 RBM19 RBMS1 CPEB4 TNRC6A	2.11e-05	347	34	5	16033648
Pubmed	Prostate cancer risk associated loci in African Americans.	LMTK2 TNRC6B	5.07e-05	11	34	2	19549807
Pubmed	Interactomes of Glycogen Synthase Kinase-3 Isoforms.	TNRC6B TNKS1BP1 SNX29 TNRC6A	5.10e-05	209	34	4	36779422
Pubmed	A Global Analysis of the Receptor Tyrosine Kinase-Protein Phosphatase Interactome.	LMTK2 USP34 MFAP1 SNX29 SLC3A1	5.23e-05	420	34	5	28065597
Pubmed	TRIM24 is an insulin-responsive regulator of P-bodies.	TNRC6B TNKS1BP1 TNRC6A	6.66e-05	80	34	3	35803934
Pubmed	Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.	USP34 TNRC6B TNKS1BP1 ALPK1	6.79e-05	225	34	4	12168954
Pubmed	An antibody-based proximity labeling map reveals mechanisms of SARS-CoV-2 inhibition of antiviral immunity.	USP34 TNRC6B MFAP1 ZNF106 RAB29 TNRC6A	6.98e-05	733	34	6	34672954
Pubmed	Mammalian miRNA RISC recruits CAF1 and PABP to affect PABP-dependent deadenylation.	TNRC6B TNRC6A	8.38e-05	14	34	2	19716330
Pubmed	RBM19 is essential for preimplantation development in the mouse.	RBM19 TNRC6A	9.66e-05	15	34	2	19087264
Pubmed	GW182 proteins directly recruit cytoplasmic deadenylase complexes to miRNA targets.	TNRC6B TNRC6A	9.66e-05	15	34	2	21981923
Pubmed	The RNA-binding protein Snd1/Tudor-SN regulates hypoxia-responsive gene expression.	TNRC6B RBMS1 TNRC6A	1.18e-04	97	34	3	37151849
Pubmed	Autism-like phenotype and risk gene mRNA deadenylation by CPEB4 mis-splicing.	TNRC6B CPEB4	1.41e-04	18	34	2	30111840
Pubmed	Prediction of the coding sequences of unidentified human genes. XIV. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.	LMTK2 TNRC6B SAMD4A	1.45e-04	104	34	3	10470851
Pubmed	Prediction of the coding sequences of unidentified human genes. IX. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro.	USP34 ATRNL1 ARAP2	1.49e-04	105	34	3	9628581
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	LMTK2 USP34 SCAF11 TNKS1BP1 TNRC6A	1.54e-04	529	34	5	14621295
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	LMTK2 ZNF106 TNKS1BP1 ALPK1 ARAP2 SAMD4A	1.68e-04	861	34	6	36931259
Pubmed	EEF1D Promotes Glioma Proliferation, Migration, and Invasion through EMT and PI3K/Akt Pathway.	TNRC6B TNKS1BP1	1.93e-04	21	34	2	33029523
Pubmed	Trinucleotide repeat containing 6a (Tnrc6a)-mediated microRNA function is required for development of yolk sac endoderm.	TNRC6B TNRC6A	2.12e-04	22	34	2	22187428
Pubmed	Trinucleotide repeat containing 6c (TNRC6c) is essential for microvascular maturation during distal airspace sacculation in the developing lung.	TNRC6B TNRC6A	2.32e-04	23	34	2	28811219
Pubmed	ATPase-Modulated Stress Granules Contain a Diverse Proteome and Substructure.	TNRC6B MFAP1 TNKS1BP1 RBMS1	2.47e-04	315	34	4	26777405
Pubmed	HDLBP Promotes Hepatocellular Carcinoma Proliferation and Sorafenib Resistance by Suppressing Trim71-dependent RAF1 Degradation.	TNRC6B MFAP1 SCAF11 RBM19 RBMS1 CPEB4 TNRC6A	3.08e-04	1371	34	7	36244648
Pubmed	Human transcription factor protein interaction networks.	RBM6 TNRC6B MFAP1 SCAF11 RBMS1 TNRC6A SENP5	3.95e-04	1429	34	7	35140242
Pubmed	TRIM65 regulates microRNA activity by ubiquitination of TNRC6.	TNRC6B TNKS1BP1 TNRC6A SENP5	4.27e-04	364	34	4	24778252
Pubmed	Proximity interactions of the ubiquitin ligase Mind bomb 1 reveal a role in regulation of epithelial polarity complex proteins.	TNRC6B MFAP1 TNRC6A	6.04e-04	169	34	3	31462741
Pubmed	A Degradation Motif in STAU1 Defines a Novel Family of Proteins Involved in Inflammation.	TNRC6B RBM19 RBMS1 CPEB4 TNRC6A	6.51e-04	724	34	5	36232890
Pubmed	Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.	USP34 TNRC6B MFAP1 ARAP2 CPEB4 TNRC6A	6.71e-04	1116	34	6	31753913
Pubmed	Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.	USP34 TNRC6B TNKS1BP1 TNRC6A	7.17e-04	418	34	4	34709266
Pubmed	An inducible CRISPR/Cas9 screen identifies DTX2 as a transcriptional regulator of human telomerase.	RBM6 USP34 TNRC6A	7.25e-04	180	34	3	35198878
Pubmed	Large-scale characterization of HeLa cell nuclear phosphoproteins.	RBM6 MFAP1 ZNF106 SCAF11 TNKS1BP1	8.78e-04	774	34	5	15302935
Pubmed	Defining the proximal interaction networks of Arf GTPases reveals a mechanism for the regulation of PLD1 and PI4KB.	USP34 TNRC6B RBM19 ARAP2 TNRC6A	8.93e-04	777	34	5	35844135
Pubmed	Identification of proximal SUMO-dependent interactors using SUMO-ID.	TNRC6B ZNF106 TNKS1BP1 SENP5	8.97e-04	444	34	4	34795231
Pubmed	Protein interaction network of the mammalian Hippo pathway reveals mechanisms of kinase-phosphatase interactions.	TNRC6B SAMD4A CPEB4 TNRC6A	9.12e-04	446	34	4	24255178
Interaction	CNOT6L interactions	TNRC6B TNKS1BP1 RAB29 CPEB4 TNRC6A	2.90e-07	93	31	5	int:CNOT6L
Interaction	CNOT7 interactions	TNRC6B TNKS1BP1 RBMS1 CPEB4 TNRC6A	2.21e-06	140	31	5	int:CNOT7
Interaction	CNOT4 interactions	TNRC6B TNKS1BP1 CPEB4 TNRC6A	2.90e-06	65	31	4	int:CNOT4
Interaction	PAN3 interactions	TNRC6B RBMS1 CPEB4 TNRC6A	2.90e-06	65	31	4	int:PAN3
Interaction	GARRE1 interactions	TNRC6B TNKS1BP1 SAMD4A CPEB4 TNRC6A	5.25e-06	167	31	5	int:GARRE1
Interaction	CEP85 interactions	TNRC6B TNKS1BP1 RBMS1 CPEB4 TNRC6A	5.57e-06	169	31	5	int:CEP85
Interaction	CNOT2 interactions	TNRC6B TNKS1BP1 RBMS1 CPEB4 TNRC6A	7.17e-06	178	31	5	int:CNOT2
Interaction	ZFP36 interactions	TNRC6B TNKS1BP1 RBMS1 CPEB4 TNRC6A	7.77e-06	181	31	5	int:ZFP36
Interaction	SMG7 interactions	RBM6 TNRC6B ZNF106 RBMS1 CPEB4 TNRC6A	7.91e-06	319	31	6	int:SMG7
Interaction	SMG5 interactions	TNRC6B RBMS1 CPEB4 TNRC6A	8.11e-06	84	31	4	int:SMG5
Interaction	ALG13 interactions	RBM6 TNRC6B RBMS1 CPEB4 TNRC6A	8.20e-06	183	31	5	int:ALG13
Interaction	GPBP1L1 interactions	TNRC6B TNKS1BP1 CPEB4 TNRC6A	8.91e-06	86	31	4	int:GPBP1L1
Interaction	CNOT3 interactions	TNRC6B TNKS1BP1 RBMS1 CPEB4 TNRC6A	1.49e-05	207	31	5	int:CNOT3
Interaction	DCAF4 interactions	USP34 TNRC6B RBMS1 SAMD4A CPEB4 TNRC6A	2.07e-05	378	31	6	int:DCAF4
Interaction	MEX3B interactions	TNRC6B TNKS1BP1 RBMS1 CPEB4 TNRC6A	2.09e-05	222	31	5	int:MEX3B
Interaction	ANKRD17 interactions	TNRC6B TNKS1BP1 RBMS1 CPEB4 TNRC6A	2.27e-05	226	31	5	int:ANKRD17
Interaction	CNOT9 interactions	TNRC6B TNKS1BP1 RBMS1 CPEB4 TNRC6A	2.52e-05	231	31	5	int:CNOT9
Interaction	CNOT11 interactions	TNRC6B TNKS1BP1 CPEB4 TNRC6A	2.53e-05	112	31	4	int:CNOT11
Interaction	UNK interactions	USP34 TNRC6B TNKS1BP1 RBMS1 CPEB4 TNRC6A	3.18e-05	408	31	6	int:UNK
Interaction	R3HDM2 interactions	TNRC6B RBMS1 CPEB4 TNRC6A	4.41e-05	129	31	4	int:R3HDM2
Interaction	CNOT10 interactions	TNRC6B TNKS1BP1 CPEB4 TNRC6A	6.24e-05	141	31	4	int:CNOT10
Interaction	TNRC6A interactions	TNRC6B TNKS1BP1 RBMS1 CPEB4 TNRC6A	6.31e-05	280	31	5	int:TNRC6A
Interaction	TNRC6B interactions	TNRC6B TNKS1BP1 RBMS1 CPEB4 TNRC6A	6.53e-05	282	31	5	int:TNRC6B
Interaction	DAZL interactions	TNRC6B RBMS1 CPEB4 TNRC6A	6.95e-05	145	31	4	int:DAZL
Interaction	CELF1 interactions	RBM6 TNRC6B RBMS1 CPEB4 TNRC6A	7.21e-05	288	31	5	int:CELF1
Interaction	FUBP3 interactions	RBM6 TNRC6B RBMS1 CPEB4 TNRC6A	8.34e-05	297	31	5	int:FUBP3
Interaction	AGO3 interactions	TNRC6B RBMS1 CPEB4 TNRC6A	8.57e-05	153	31	4	int:AGO3
Interaction	CNOT6 interactions	TNRC6B TNKS1BP1 TNRC6A	8.64e-05	56	31	3	int:CNOT6
Interaction	CPEB4 interactions	TNRC6B RBMS1 CPEB4 TNRC6A	9.24e-05	156	31	4	int:CPEB4
Interaction	CNOT1 interactions	TNRC6B TNKS1BP1 RBMS1 CPEB4 TNRC6A	9.45e-05	305	31	5	int:CNOT1
Interaction	NME7 interactions	TNRC6B SCAF11 CPEB4 TNRC6A	1.02e-04	160	31	4	int:NME7
Interaction	YTHDF2 interactions	TNRC6B TNKS1BP1 RBMS1 CPEB4 TNRC6A	1.05e-04	312	31	5	int:YTHDF2
Interaction	PATL1 interactions	TNRC6B RBMS1 CPEB4 TNRC6A	1.50e-04	177	31	4	int:PATL1
Interaction	AGO1 interactions	TNRC6B RBMS1 CPEB4 TNRC6A	1.71e-04	183	31	4	int:AGO1
Interaction	FAM193A interactions	TNRC6B CPEB4 TNRC6A	1.75e-04	71	31	3	int:FAM193A
Interaction	CNOT8 interactions	TNRC6B CPEB4 TNRC6A	1.98e-04	74	31	3	int:CNOT8
Interaction	FAM120C interactions	TNRC6B RBMS1 CPEB4 TNRC6A	2.01e-04	191	31	4	int:FAM120C
Interaction	GPBP1 interactions	TNRC6B CPEB4 TNRC6A	2.06e-04	75	31	3	int:GPBP1
Interaction	RBM47 interactions	TNRC6B RBM19 RBMS1 CPEB4	2.59e-04	204	31	4	int:RBM47
Interaction	RBMS1 interactions	TNRC6B RBMS1 CPEB4 TNRC6A	2.74e-04	207	31	4	int:RBMS1
Interaction	ZC3H7A interactions	TNRC6B RBMS1 CPEB4 TNRC6A	3.16e-04	215	31	4	int:ZC3H7A
Interaction	OTUD4 interactions	TNRC6B RBMS1 CPEB4 TNRC6A	4.50e-04	236	31	4	int:OTUD4
Interaction	RC3H2 interactions	TNRC6B TNKS1BP1 RBM19 RBMS1 CPEB4 TNRC6A	4.66e-04	667	31	6	int:RC3H2
Interaction	RC3H1 interactions	TNRC6B TNKS1BP1 RBM19 RBMS1 CPEB4 TNRC6A	5.05e-04	677	31	6	int:RC3H1
Interaction	YTHDF3 interactions	TNRC6B RBMS1 CPEB4 TNRC6A	5.26e-04	246	31	4	int:YTHDF3
Interaction	DCP1B interactions	TNRC6B CPEB4 TNRC6A	5.40e-04	104	31	3	int:DCP1B
Interaction	HELZ interactions	TNRC6B RBMS1 CPEB4 TNRC6A	6.20e-04	257	31	4	int:HELZ
Interaction	PRRC2B interactions	TNRC6B RBMS1 CPEB4 TNRC6A	6.95e-04	265	31	4	int:PRRC2B
Interaction	AGO4 interactions	USP34 TNRC6B TNRC6A	7.80e-04	118	31	3	int:AGO4
Interaction	KIZ interactions	TNRC6B TNRC6A	7.85e-04	27	31	2	int:KIZ
Interaction	SAMD4B interactions	TNRC6B SAMD4A CPEB4	8.60e-04	122	31	3	int:SAMD4B
Interaction	PUM1 interactions	TNRC6B RBMS1 CPEB4 TNRC6A	9.36e-04	287	31	4	int:PUM1
Interaction	MARF1 interactions	TNRC6B CPEB4 TNRC6A	9.88e-04	128	31	3	int:MARF1
Interaction	TCHP interactions	TNRC6B CPEB4 TNRC6A	1.06e-03	131	31	3	int:TCHP
Interaction	UBAP2L interactions	TNRC6B RBMS1 CPEB4 TNRC6A	1.08e-03	298	31	4	int:UBAP2L
Interaction	EIF4ENIF1 interactions	TNRC6B RBMS1 CPEB4 TNRC6A	1.10e-03	300	31	4	int:EIF4ENIF1
Interaction	YTHDF1 interactions	TNRC6B RBMS1 CPEB4 TNRC6A	1.13e-03	302	31	4	int:YTHDF1
Interaction	TNRC6C interactions	TNRC6B CPEB4 TNRC6A	1.23e-03	138	31	3	int:TNRC6C
Interaction	OBI1 interactions	TNRC6B TNKS1BP1 TNRC6A	1.25e-03	139	31	3	int:OBI1
Interaction	PUM2 interactions	TNRC6B RBMS1 CPEB4	1.39e-03	144	31	3	int:PUM2
Interaction	CPEB1 interactions	TNRC6B RBMS1 TNRC6A	1.44e-03	146	31	3	int:CPEB1
Interaction	SAV1 interactions	TNRC6B CPEB4 TNRC6A	1.59e-03	151	31	3	int:SAV1
GeneFamily	RNA binding motif containing	RBM6 RBM19 RBMS1 CPEB4	1.95e-04	213	25	4	725
GeneFamily	Ataxins\|Trinucleotide repeat containing	TNRC6B TNRC6A	5.40e-04	25	25	2	775
GeneFamily	Sterile alpha motif domain containing	ARAP2 SAMD4A	6.53e-03	88	25	2	760
Coexpression	IVANOVA_HEMATOPOIESIS_MATURE_CELL	LMTK2 TNRC6B DEDD2 RBMS1 CPEB4	3.36e-05	298	33	5	M11205
Coexpression	IVANOVA_HEMATOPOIESIS_MATURE_CELL	LMTK2 TNRC6B DEDD2 RBMS1 CPEB4	4.51e-05	317	33	5	MM1163
Coexpression	GSE10147_IL3_VS_IL3_AND_HIVP17_STIM_PDC_UP	ZNF106 ALPK1 ATRNL1 TNRC6A	5.50e-05	166	33	4	M344
Coexpression	GSE29164_UNTREATED_VS_CD8_TCELL_AND_IL12_TREATED_MELANOMA_DAY3_DN	TNRC6B MFAP1 ZNF106 RAB29	1.13e-04	200	33	4	M8485
Coexpression	GSE17721_4_VS_24H_CPG_BMDC_UP	EMP3 RBMS1 NRK SAMD4A	1.13e-04	200	33	4	M4130
Coexpression	LAKE_ADULT_KIDNEY_C14_DISTAL_CONVOLUTED_TUBULE	TNRC6B SNX29 CPEB4 TNRC6A	1.32e-04	208	33	4	M39233
Coexpression	MURARO_PANCREAS_BETA_CELL	USP34 DPP6 ZNF106 RAB29 SNX29 ATRNL1 CPEB4	1.46e-04	946	33	7	M39169
Coexpression	LAKE_ADULT_KIDNEY_C5_PROXIMAL_TUBULE_EPITHELIAL_CELLS_STRESS_INFLAM	RBM6 TNRC6B CHRM3 SNX29 TNRC6A	1.64e-04	417	33	5	M39224
Coexpression	LAKE_ADULT_KIDNEY_C3_PROXIMAL_TUBULE_EPITHELIAL_CELLS_S1_S2	RBM6 TNRC6B SNX29 TNRC6A	1.66e-04	221	33	4	M39222
Coexpression	MARTINEZ_RB1_TARGETS_UP	RBM6 LMTK2 USP34 ZNF106 SCAF11 RBMS1	1.97e-04	690	33	6	M12224
ToppCell	Tracheal-NucSeq\|Tracheal / Cell types per location group and 10X technology with lineage, and cell group designations	RBM6 USP34 TNRC6B CHRM3 TNRC6A	3.45e-07	199	33	5	94b94b17ca18b8dc27b91da1f2ccf89e03cc7035
ToppCell	renal_cortex_nuclei\|World / Celltypes from Cells and Nuclei per compartment and clinical group	RBM6 TNRC6B SNX29 TNRC6A	1.19e-05	192	33	4	e8cc4d08fcfceeab75a02558817e4ccd7dbafe3a
ToppCell	human_hepatoblastoma\|World / Sample and Cell Type and Tumor Cluster (all cells)	TNRC6B SCAF11 RBMS1 TNRC6A	1.22e-05	193	33	4	e6a688bc834f845ff64dae1be64f073eec5091a1
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	DPP6 SNX29 SLC3A1 CPEB4	1.22e-05	193	33	4	82e8a4c40299ffcdfd5a0da711bb9de6fb8a2eaa
ToppCell	Brain_organoid-organoid_Tanaka_cellReport-6m\|organoid_Tanaka_cellReport / Sample Type, Dataset, Time_group, and Cell type.	ZNF106 SCAF11 EMP3 RBMS1	1.40e-05	200	33	4	5ba4ed490c64b3bb738e7729669f893fa73aa56f
Drug	Amprolium hydrochloride [137-88-2]; Up 200; 12.6uM; MCF7; HT_HG-U133A	USP34 ALPK1 CHRM3 RBM19 ATRNL1 SLC3A1	3.44e-07	196	33	6	1479_UP
Drug	Melatonin [73-31-4]; Down 200; 17.2uM; MCF7; HT_HG-U133A	USP34 ALPK1 SLC3A1 SAMD4A SENP5	8.13e-06	193	33	5	3293_DN
Drug	Homosalate [118-56-9]; Down 200; 15.2uM; PC3; HT_HG-U133A	USP34 TNRC6B ALPK1 RBM19 SENP5	8.55e-06	195	33	5	4533_DN
Drug	1,4-bis(diphenylphosphino)butane	DPP6 GRP	1.22e-05	4	33	2	CID000082124
Drug	Rc 3120	BRS3 GRP	2.03e-05	5	33	2	CID005492660
Drug	L-365,260	BRS3 GRP MOV10L1	2.08e-05	37	33	3	CID000104929
Drug	AC1NUK9U	BRS3 GRP	4.26e-05	7	33	2	CID005481220
Drug	Rc 3100	BRS3 GRP	5.67e-05	8	33	2	CID005487260
Drug	kuwanon	BRS3 GRP	7.29e-05	9	33	2	CID005281667
Drug	2-aminoacetophenone	TCFL5 SLC3A1	1.33e-04	12	33	2	CID000011952
Drug	Ici 216140	BRS3 GRP	1.33e-04	12	33	2	CID005487263
Drug	Methazolamide [554-57-4]; Up 200; 17uM; MCF7; HT_HG-U133A	ALPK1 CHRM3 RBM19 SAMD4A	1.69e-04	193	33	4	3474_UP
Drug	Pentoxifylline [6493-05-6]; Down 200; 14.4uM; MCF7; HT_HG-U133A	USP34 ALPK1 CHRM3 SERGEF	1.72e-04	194	33	4	6021_DN
Drug	2-propylpentanoic acid; Down 200; 500uM; MCF7; HT_HG-U133A	USP34 RBM19 SAMD4A SENP5	1.76e-04	195	33	4	1665_DN
Drug	Propoxycaine hydrochloride [550-83-4]; Down 200; 12uM; MCF7; HT_HG-U133A	RAB29 RBM19 SLC3A1 SAMD4A	1.76e-04	195	33	4	3583_DN
Drug	Spectinomycin dihydrochloride [21736-83-4]; Down 200; 9.8uM; MCF7; HT_HG-U133A	TNRC6B CHRM3 RBM19 SENP5	1.79e-04	196	33	4	3327_DN
Drug	Phenylpropanolamine hydrochloride [154-41-6]; Up 200; 21.4uM; MCF7; HT_HG-U133A	CHRM3 SLC3A1 SERGEF SENP5	1.79e-04	196	33	4	5298_UP
Drug	Naloxone hydrochloride [357-08-4]; Down 200; 11uM; MCF7; HT_HG-U133A	ALPK1 ATRNL1 SLC3A1 SENP5	1.83e-04	197	33	4	5606_DN
Drug	alpha-estradiol; Up 200; 0.01uM; MCF7; HT_HG-U133A_EA	RBM6 ALPK1 ARAP2 SENP5	1.83e-04	197	33	4	1048_UP
Drug	Meprylcaine hydrochloride [956-03-6]; Down 200; 14.8uM; MCF7; HT_HG-U133A	USP34 ALPK1 CHRM3 SENP5	1.83e-04	197	33	4	3544_DN
Drug	Phyllolitorin	BRS3 GRP	1.83e-04	14	33	2	CID005748287
Drug	Nefopam hydrochloride [23327-57-3]; Down 200; 13.8uM; PC3; HT_HG-U133A	LMTK2 CHRM3 SLC3A1 SAMD4A	1.86e-04	198	33	4	3730_DN
Drug	Naringenine [480-41-1]; Up 200; 14.6uM; MCF7; HT_HG-U133A	EMP3 BRS3 SLC3A1 SAMD4A	1.86e-04	198	33	4	4422_UP
Drug	Benzamil hydrochloride [2898-76-2]; Down 200; 11.2uM; PC3; HT_HG-U133A	LMTK2 SLC3A1 SERGEF SAMD4A	1.86e-04	198	33	4	3738_DN
Drug	(-)-MK 801 hydrogen maleate [77086-19-2]; Down 200; 11.8uM; HL60; HT_HG-U133A	TNRC6B RBM19 SLC3A1 SENP5	1.86e-04	198	33	4	3081_DN
Drug	Ranitidine hydrochloride [66357-59-3]; Down 200; 11.4uM; MCF7; HT_HG-U133A	USP34 ALPK1 CHRM3 RBM19	1.86e-04	198	33	4	2251_DN
Drug	Tropine [120-29-6]; Down 200; 28.4uM; MCF7; HT_HG-U133A	CHRM3 SLC3A1 SERGEF SENP5	1.86e-04	198	33	4	3569_DN
Drug	Baclofen (R,S) [1134-47-0]; Down 200; 18.8uM; MCF7; HT_HG-U133A	TNRC6B ALPK1 RBM19 SLC3A1	1.90e-04	199	33	4	1536_DN
Disease	alcohol consumption measurement	MFAP1 DPP6 SCAF11 ALPK1 RAB29 SERGEF ARAP2 TNRC6A	4.11e-05	1242	32	8	EFO_0007878
Disease	smoking status measurement	LMTK2 DPP6 SNX29 RBMS1 ARAP2 CPEB4 TNRC6A	2.02e-04	1160	32	7	EFO_0006527
Disease	FEV/FEC ratio	USP34 ZNF106 GRP CHRM3 RBMS1 ARAP2 CPEB4	2.87e-04	1228	32	7	EFO_0004713
Disease	bitter alcoholic beverage consumption measurement	TNRC6B DPP6 TNRC6A	4.04e-04	133	32	3	EFO_0010092
Disease	smoking cessation	DPP6 RBMS1 ARAP2 TNRC6A	4.07e-04	325	32	4	EFO_0004319
Disease	gestational age	DPP6 MOV10L1 SENP5	4.49e-04	138	32	3	EFO_0005112
Disease	uric acid measurement	LMTK2 USP34 RAB29 RBMS1 CPEB4	4.71e-04	610	32	5	EFO_0004761
Disease	risk-taking behaviour	DPP6 RBM19 ATRNL1 CPEB4 TNRC6A	1.29e-03	764	32	5	EFO_0008579
Disease	metabolic syndrome	RBM6 ARAP2 TNRC6A	1.32e-03	200	32	3	EFO_0000195
Disease	corpus callosum posterior volume measurement	RBM6 TNRC6B	1.46e-03	52	32	2	EFO_0010298
Disease	prostate carcinoma, type 2 diabetes mellitus	LMTK2 TNRC6B	1.88e-03	59	32	2	EFO_0001663, MONDO_0005148
Disease	ceramide measurement	ZNF106 SNX29 SAMD4A	2.09e-03	235	32	3	EFO_0010222
Disease	body weight	TNRC6B RAB29 RBM19 RBMS1 CPEB4 TNRC6A	2.10e-03	1261	32	6	EFO_0004338
Disease	chronotype measurement	RBM6 USP34 TNRC6B DEDD2 RBM19	2.43e-03	882	32	5	EFO_0008328
Disease	thyroxine measurement	SNX29 NRK	3.67e-03	83	32	2	EFO_0005130
Disease	age at menarche	RBM6 USP34 ATRNL1 TNRC6A	3.74e-03	594	32	4	EFO_0004703
Disease	cognitive function measurement	RBM6 USP34 SNX29 RBMS1 CPEB4 TNRC6A	3.98e-03	1434	32	6	EFO_0008354
Disease	S-6-hydroxywarfarin to S-warfarin ratio measurement	ATRNL1 SERGEF	4.12e-03	88	32	2	EFO_0803332
Disease	urate measurement, bone density	RBM6 CHRM3 SNX29 MOV10L1	4.33e-03	619	32	4	EFO_0003923, EFO_0004531
Disease	social interaction measurement	TNRC6B DPP6	4.68e-03	94	32	2	EFO_0009592
Disease	alcohol use disorder measurement, alcohol consumption measurement	DPP6 TNRC6A	4.97e-03	97	32	2	EFO_0007878, EFO_0009458
Disease	reticulocyte measurement	RBM6 USP34 TNRC6B RBMS1 CPEB4	5.18e-03	1053	32	5	EFO_0010700
Disease	chronic obstructive pulmonary disease	CHRM3 RBMS1 ARAP2 CPEB4	6.27e-03	688	32	4	EFO_0000341
Disease	neuritic plaque measurement	DPP6 ALPK1 CHRM3	6.31e-03	349	32	3	EFO_0006798
Disease	grip strength measurement	TNRC6B SAMD4A TNRC6A	6.36e-03	350	32	3	EFO_0006941
Disease	cortical thickness	TNRC6B ZNF106 RAB29 CPEB4 TNRC6A	6.53e-03	1113	32	5	EFO_0004840
Disease	atrial fibrillation	USP34 ALPK1 CPEB4	7.46e-03	371	32	3	EFO_0000275

Protein segments in the cluster

Peptide	Gene	Start	Entry
NDGQKNSTRLWNSQS	ERVK-9	501	Q9UKH3
SWNNNDAAASLENSA	CHRM3	336	P20309
KSVAWQNSNEENSSS	ARAP2	316	Q8WZ64
SSSSANSQQGQWETG	DEDD2	136	Q8WXF8
NKSLSGSQTSSAWSN	ALPK1	571	Q96QP1
EAQDKANSASSHNWN	RBM19	501	Q9Y4C8
NNSSSSSNSGWDQLS	RBMS1	46	P29558
TNATTFSNSQRWKQD	RAB29	91	O14966
SFDSAWGQESAQNTK	MFAP1	401	P55081
TGNWNHAQDTKSSGQ	MOV10L1	671	Q9BXT6
SGSGNKKSSNWNNNQ	IHO1	16	Q8IYA8
NQQPSWDSEDSSNFK	GRP	106	P07492
WNALKPNTNSRDSSN	LMTK2	426	Q8IWU2
NKNHCESWESGNTNN	ATRNL1	636	Q5VV63
NNNTAANGSSAGSAW	CPEB4	46	Q17RY0
NNDTKTWACSNVSEN	EMP3	46	P54852
NSSNDNIQSITSGDW	DPP6	471	P42658
RNENSGNSWNKNFGS	SCAF11	1051	Q99590
SSQNRQNWLAASESS	NRK	826	Q7Z2Y5
NSNGSQSSNSWKIDS	SNX29P2	161	Q8IUI4
NSDWSSDTNRQGQQS	RBM6	771	P78332
NWKERQSETSTQSQS	SERGEF	436	Q9UGK8
NGSQSSNSWKIDSLS	SNX29	316	Q8TEQ0
ASGRKSSWQGENQSQ	PRDM7	401	Q9NQW5
WDNSSNAGFSEASNT	SLC3A1	511	Q07837
VVSNDNTNKGWSGDN	BRS3	26	P32247
DQQNGSATNAWDQSS	SENP5	346	Q96HI0
SDNKACTGDSWTQNT	SOGA1	721	O94964
GQRDQSSWQNSDASQ	TNKS1BP1	1041	Q9C0C2
DSSEDQVENSKNSWS	USP34	1471	Q70CQ2
ATQGAWQSSESSQAN	TCFL5	371	Q9UL49
WQSSESSQANLGEQA	TCFL5	376	Q9UL49
SNGNWKSSVRSTNNW	ZNF106	221	Q9H2Y7
QNSDDKLNGWQNSRD	SAMD4A	181	Q9UPU9
NINPNNSSGWDESSK	TNRC6A	901	Q8NDV7
SNSTTENNNGLGNWR	TNRC6B	271	Q9UPQ9
SVQKSTGSKNDSWDN	TNRC6B	461	Q9UPQ9
TGSKNDSWDNNNRST	TNRC6B	466	Q9UPQ9