Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
Domain	WD40_repeat_dom	KNTC1 TULP4 WDR7 ARHGEF10 TLE2 TLE4 UBR4 WDR90 LRRK1 RMC1 WDR53	2.71e-08	297	75	11	IPR017986
Domain	-	TULP4 WDR7 ARHGEF10 TLE2 TLE4 WDR90 RMC1 WDR53	5.61e-05	333	75	8	2.130.10.10
Domain	WD40/YVTN_repeat-like_dom	TULP4 WDR7 ARHGEF10 TLE2 TLE4 WDR90 RMC1 WDR53	5.85e-05	335	75	8	IPR015943
Domain	Groucho_enhance	TLE2 TLE4	1.58e-04	5	75	2	IPR009146
Domain	TLE_N	TLE2 TLE4	1.58e-04	5	75	2	PF03920
Domain	Groucho/TLE_N	TLE2 TLE4	1.58e-04	5	75	2	IPR005617
Domain	EGF	RELN TNC FAT3 LAMA3 LRP4 TECTA	3.63e-04	235	75	6	SM00181
Domain	EGF-like_dom	RELN TNC FAT3 LAMA3 LRP4 TECTA	4.94e-04	249	75	6	IPR000742
Domain	WD40_repeat_CS	WDR7 TLE2 TLE4 WDR90 WDR53	5.16e-04	164	75	5	IPR019775
Domain	WD40	TULP4 WDR7 TLE2 TLE4 WDR90 WDR53	6.07e-04	259	75	6	PF00400
Domain	WD40	TULP4 WDR7 TLE2 TLE4 WDR90 WDR53	7.26e-04	268	75	6	SM00320
Domain	WD40_repeat	TULP4 WDR7 TLE2 TLE4 WDR90 WDR53	7.84e-04	272	75	6	IPR001680
Domain	WD_REPEATS_1	TULP4 WDR7 TLE2 TLE4 WDR90 WDR53	8.78e-04	278	75	6	PS00678
Domain	WD_REPEATS_2	TULP4 WDR7 TLE2 TLE4 WDR90 WDR53	8.95e-04	279	75	6	PS50082
Domain	WD_REPEATS_REGION	TULP4 WDR7 TLE2 TLE4 WDR90 WDR53	8.95e-04	279	75	6	PS50294
Domain	USP_CS	USP50 USP8 USP4	2.37e-03	66	75	3	IPR018200
Domain	USP_1	USP50 USP8 USP4	2.81e-03	70	75	3	PS00972
Domain	UCH	USP50 USP8 USP4	2.92e-03	71	75	3	PF00443
Domain	USP_2	USP50 USP8 USP4	2.92e-03	71	75	3	PS00973
Domain	USP_3	USP50 USP8 USP4	3.04e-03	72	75	3	PS50235
Domain	USP_dom	USP50 USP8 USP4	3.04e-03	72	75	3	IPR028889
Domain	Peptidase_C19_UCH	USP50 USP8 USP4	3.04e-03	72	75	3	IPR001394
Domain	EGF_1	RELN TNC FAT3 LAMA3 LRP4	3.62e-03	255	75	5	PS00022
Domain	EGF-like_CS	RELN TNC FAT3 LAMA3 LRP4	4.00e-03	261	75	5	IPR013032
Domain	EGF_2	RELN TNC FAT3 LAMA3 LRP4	4.26e-03	265	75	5	PS01186
Pubmed	RNF43 germline and somatic mutation in serrated neoplasia pathway and its association with BRAF mutation.	BRAF RNF43	5.23e-06	2	80	2	27329244
Pubmed	Exome sequencing revealed comparable frequencies of RNF43 and BRAF mutations in Middle Eastern colorectal cancer.	BRAF RNF43	5.23e-06	2	80	2	35907983
Pubmed	RNF43 mutation is associated with aggressive tumor biology along with BRAF V600E mutation in right-sided colorectal cancer.	BRAF RNF43	5.23e-06	2	80	2	32236609
Pubmed	UBE2S interacting with TRIM21 mediates the K11-linked ubiquitination of LPP to promote the lymphatic metastasis of bladder cancer.	UBR4 RNF213 TRIP13	1.51e-05	21	80	3	37422473
Pubmed	Obstructed migration of Purkinje cells in the developing cerebellum of the reeler mutant mouse.	RELN TNC	1.57e-05	3	80	2	7506500
Pubmed	USP8, USP48, and BRAF mutations differ in their genotype-phenotype correlation in Asian Indian patients with Cushing's disease.	USP8 BRAF	1.57e-05	3	80	2	34664215
Pubmed	Structural and functional analyses of the mammalian TIN2-TPP1-TRF2 telomeric complex.	TINF2 TPP1	1.57e-05	3	80	2	29160297
Pubmed	Exome sequencing reveals pathogenic mutations in 91 strains of mice with Mendelian disorders.	KNTC1 TPP1 LRP4 LRRK1	2.37e-05	72	80	4	25917818
Pubmed	TLE expression correlates with mouse embryonic segmentation, neurogenesis, and epithelial determination.	TLE2 TLE4	3.13e-05	4	80	2	8645603
Pubmed	Binding of TPP1 protein to TIN2 protein is required for POT1a,b protein-mediated telomere protection.	TINF2 TPP1	3.13e-05	4	80	2	25056954
Pubmed	Usp39 is essential for mitotic spindle checkpoint integrity and controls mRNA-levels of aurora B.	USP8 USP4	3.13e-05	4	80	2	18728397
Pubmed	TIN2 Functions with TPP1/POT1 To Stimulate Telomerase Processivity.	TINF2 TPP1	3.13e-05	4	80	2	31383750
Pubmed	TIN2-tethered TPP1 recruits human telomerase to telomeres in vivo.	TINF2 TPP1	3.13e-05	4	80	2	20404094
Pubmed	Loss of mitochondrial ClpP, Lonp1, and Tfam triggers transcriptional induction of Rnf213, a susceptibility factor for moyamoya disease.	RNF213 TFAM	3.13e-05	4	80	2	32342250
Pubmed	High-density SNP association study and copy number variation analysis of the AUTS1 and AUTS5 loci implicate the IMMP2L-DOCK4 gene region in autism susceptibility.	RELN SLC13A1 CCDC148	4.55e-05	30	80	3	19401682
Pubmed	An antibody-based proximity labeling map reveals mechanisms of SARS-CoV-2 inhibition of antiviral immunity.	KNTC1 USP8 ARHGEF10 EIF3L RNF213 PRR14L RREB1 ITPRIPL1 ADCY9	4.77e-05	733	80	9	34672954
Pubmed	Human homologs of a Drosophila Enhancer of split gene product define a novel family of nuclear proteins.	TLE2 TLE4	5.20e-05	5	80	2	1303260
Pubmed	Human Telomere Repeat Binding Factor TRF1 Replaces TRF2 Bound to Shelterin Core Hub TIN2 when TPP1 Is Absent.	TINF2 TPP1	5.20e-05	5	80	2	31158366
Pubmed	Decrease in neuronal nicotinic acetylcholine receptor subunit and PSD-93 transcript levels in the male mouse MPG after cavernous nerve injury or explant culture.	DLG2 CHRNA3	5.20e-05	5	80	2	24049141
Pubmed	Molecular cloning and expression of mouse and human cDNA encoding AES and ESG proteins with strong similarity to Drosophila enhancer of split groucho protein.	TLE2 TLE4	5.20e-05	5	80	2	8365415
Pubmed	Rectification of muscle and nerve deficits in paralyzed ryanodine receptor type 1 mutant embryos.	LRP4 RYR3	7.79e-05	6	80	2	26025922
Pubmed	Protein characterization and targeted disruption of Grg, a mouse gene related to the groucho transcript of the Drosophila Enhancer of split complex.	TLE2 TLE4	7.79e-05	6	80	2	8573724
Pubmed	The timing of cortical neurogenesis is encoded within lineages of individual progenitor cells.	RELN TLE4	7.79e-05	6	80	2	16680166
Pubmed	Personal receptor repertoires: olfaction as a model.	OR5AR1 OR51J1 OR5D13	9.33e-05	38	80	3	22908908
Pubmed	Genome-wide association analysis of susceptibility and clinical phenotype in multiple sclerosis.	AXDND1 RELN WDR7	1.01e-04	39	80	3	19010793
Pubmed	Telomere protection by TPP1/POT1 requires tethering to TIN2.	TINF2 TPP1	1.09e-04	7	80	2	22099311
Pubmed	A Gro/TLE-NuRD corepressor complex facilitates Tbx20-dependent transcriptional repression.	TLE2 TLE4	1.09e-04	7	80	2	24024827
Pubmed	Deubiquitylation and stabilization of PTEN by USP13.	USP8 USP4	1.09e-04	7	80	2	24270891
Pubmed	Comparative sequence analysis of a single-gene conserved segment in mouse and human.	AP4E1 ITPRIPL1	1.09e-04	7	80	2	14694903
Pubmed	Poly (ADP-Ribose) Polymerase 1 Regulates Cajal-Retzius Cell Development and Neural Precursor Cell Adhesion.	RELN TNC	1.09e-04	7	80	2	34708032
Pubmed	Localization of extracellular matrix receptors in ICGN mice, a strain of mice with hereditary nephrotic syndrome.	TNC RP1	1.09e-04	7	80	2	11767049
Pubmed	Circular RNAs regulate neuron size and migration of midbrain dopamine neurons during development.	TULP4 FAT3	1.45e-04	8	80	2	39117691
Pubmed	The Groucho-related gene family regulates the gonadotropin-releasing hormone gene through interaction with the homeodomain proteins MSX1 and OCT1.	TLE2 TLE4	1.45e-04	8	80	2	16002402
Pubmed	The shelterin component TPP1 is a binding partner and substrate for the deubiquitinating enzyme USP7.	TINF2 TPP1	1.45e-04	8	80	2	25172512
Pubmed	Nolz1 promotes striatal neurogenesis through the regulation of retinoic acid signaling.	TLE2 TLE4	1.45e-04	8	80	2	20735826
Pubmed	Defects During Mecp2 Null Embryonic Cortex Development Precede the Onset of Overt Neurological Symptoms.	RELN GRM5 ADCY9	1.55e-04	45	80	3	25979088
Pubmed	Pharmacogenetics of antipsychotic response in the CATIE trial: a candidate gene analysis.	RELN GRM5 CHRNA3 ADCY9	1.63e-04	118	80	4	19156168
Pubmed	BRCA1 binds TERRA RNA and suppresses R-Loop-based telomeric DNA damage.	TINF2 TPP1	1.86e-04	9	80	2	34112789
Pubmed	Multiple genetic loci influence serum urate levels and their relationship with gout and cardiovascular disease risk factors.	SLC22A11 RREB1	1.86e-04	9	80	2	20884846
Pubmed	Neural bHLH genes control the neuronal versus glial fate decision in cortical progenitors.	RELN TNC	1.86e-04	9	80	2	11239431
Pubmed	The differential modulation of USP activity by internal regulatory domains, interactors and eight ubiquitin chain types.	USP8 USP4	1.86e-04	9	80	2	22195557
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	PHF12 LRP4 DIDO1 DEPDC5 WDR90 LRRK1 ADCY9	2.21e-04	529	80	7	14621295
Pubmed	Cortical migration defects in mice expressing A-RAF from the B-RAF locus.	RELN BRAF	2.32e-04	10	80	2	16980614
Pubmed	Spatial distribution of the full-length members of the Grg family during embryonic neurogenesis reveals a "Grg-mediated repression map" in the mouse telencephalon.	TLE2 TLE4	2.32e-04	10	80	2	30571765
Pubmed	Comprehensive analysis of the expression patterns of the adenylate cyclase gene family in the developing and adult mouse brain.	RELN ADCY9	2.32e-04	10	80	2	16615126
Pubmed	Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.	ZFHX4 PHF12 FAT3 LRP4 RNF213 RREB1 TRIP13 TFAM RNF43 ADCY9	2.39e-04	1116	80	10	31753913
Pubmed	Coexpression of Cux-1 and Notch signaling pathway components during kidney development.	TLE2 TLE4	2.84e-04	11	80	2	15499562
Pubmed	Pax6-dependent regulation of adhesive patterning, R-cadherin expression and boundary formation in developing forebrain.	RELN TNC	2.84e-04	11	80	2	9367432
Pubmed	Inflammation-dependent overexpression of c-Myc enhances CRL4DCAF4 E3 ligase activity and promotes ubiquitination of ST7 in colitis-associated cancer.	KNTC1 TLE2 PRR14L UBASH3B TECTA	3.24e-04	257	80	5	30945288
Pubmed	All Tcf HMG box transcription factors interact with Groucho-related co-repressors.	TLE2 TLE4	3.40e-04	12	80	2	11266540
Pubmed	Discovery and Characterization of ZUFSP/ZUP1, a Distinct Deubiquitinase Class Important for Genome Stability.	USP8 USP4 DEPDC5 TFAM	3.78e-04	147	80	4	29576527
Pubmed	Evidence for complex multigenic inheritance of radiation AML susceptibility in mice revealed using a surrogate phenotypic assay.	LAMA3 RMC1	4.01e-04	13	80	2	16093251
Pubmed	SOX5 postmitotically regulates migration, postmigratory differentiation, and projections of subplate and deep-layer neocortical neurons.	RELN TLE4	4.01e-04	13	80	2	18840685
Pubmed	Cytosolic Iron-Sulfur Assembly Is Evolutionarily Tuned by a Cancer-Amplified Ubiquitin Ligase.	TPP1 TFAM	4.01e-04	13	80	2	29225034
Pubmed	Neurog2 simultaneously activates and represses alternative gene expression programs in the developing neocortex.	TLE2 TLE4	4.01e-04	13	80	2	22735158
Pubmed	In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.	KNTC1 USP8 SNX25 UBR4 SKIDA1 DLG2 IRAK3 OR5AR1 TRIP13 TFAM CCDC148	4.54e-04	1442	80	11	35575683
Pubmed	Comparison of the Spatiotemporal Expression Patterns of Three Cre Lines, Emx1IRES-Cre, D6-Cre and hGFAP-Cre, Commonly Used in Neocortical Development Research.	RELN TLE4	4.67e-04	14	80	2	34550336
Pubmed	Continuing role for mouse Numb and Numbl in maintaining progenitor cells during cortical neurogenesis.	RELN TLE4	4.67e-04	14	80	2	15273690
Pubmed	Nkx2.2-repressor activity is sufficient to specify alpha-cells and a small number of beta-cells in the pancreatic islet.	TLE2 TLE4	4.67e-04	14	80	2	17202186
Pubmed	Deubiquitinating enzymes: a new class of biological regulators.	USP8 USP4	5.38e-04	15	80	2	9827704
Pubmed	Epithelial-Macrophage Crosstalk Initiates Sterile Inflammation in Embryonic Skin.	TNC LAMA3	5.38e-04	15	80	2	34721382
Pubmed	Developmental restriction of Mash-2 expression in trophoblast correlates with potential activation of the notch-2 pathway.	TLE2 TLE4	5.38e-04	15	80	2	9291577
Pubmed	SOX5 controls the sequential generation of distinct corticofugal neuron subtypes.	RELN TLE4	5.38e-04	15	80	2	18215621
Pubmed	Efficient transposition of the piggyBac (PB) transposon in mammalian cells and mice.	ZFHX4 WDR7	6.14e-04	16	80	2	16096065
Pubmed	SLX4IP promotes RAP1 SUMOylation by PIAS1 to coordinate telomere maintenance through NF-κB and Notch signaling.	TINF2 SLX4IP	6.14e-04	16	80	2	34187905
Pubmed	Specific glial populations regulate hippocampal morphogenesis.	RELN TNC	6.14e-04	16	80	2	19020026
Pubmed	Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.	USP8 RELN SETMAR ARHGEF10 TPP1 UBR4 LRP4 DLG2 INTS8 RYR3	7.21e-04	1285	80	10	35914814
Pubmed	Disruptions in asymmetric centrosome inheritance and WDR62-Aurora kinase B interactions in primary microcephaly.	RELN TLE4	7.81e-04	18	80	2	28272472
Pubmed	NFIX regulates neural progenitor cell differentiation during hippocampal morphogenesis.	RELN TNC	7.81e-04	18	80	2	23042739
Pubmed	Divergent roles of ApoER2 and Vldlr in the migration of cortical neurons.	RELN TLE4	7.81e-04	18	80	2	17913789
Pubmed	Genome-wide association analysis demonstrates the highly polygenic character of age-related hearing impairment.	DEPDC5 PRR14L	7.81e-04	18	80	2	24939585
Pubmed	Groucho co-repressor proteins regulate β cell development and proliferation by repressing Foxa1 in the developing mouse pancreas.	TLE2 TLE4	7.81e-04	18	80	2	33658226
Pubmed	Temporal regulation of a paired-like homeodomain repressor/TLE corepressor complex and a related activator is required for pituitary organogenesis.	TLE2 TLE4	7.81e-04	18	80	2	11731482
Pubmed	Human and mouse proteases: a comparative genomic approach.	USP50 USP8 USP4	8.79e-04	81	80	3	12838346
Pubmed	Transcriptional regulation of cortical neuron migration by POU domain factors.	RELN TLE4	9.66e-04	20	80	2	11859196
Pubmed	Neuronal production and precursor proliferation defects in the neocortex of mice with loss of function in the canonical Wnt signaling pathway.	RELN TLE4	9.66e-04	20	80	2	16920270
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	TULP4 PHF12 UBR4 LRP4 DEPDC5 WDR90 LRRK1 RNF43 ADCY9	9.82e-04	1105	80	9	35748872
Pubmed	Identification of SUMO Binding Proteins Enriched after Covalent Photo-Cross-Linking.	UBR4 RNF213 DIDO1 RREB1 TRIP13	1.03e-03	332	80	5	32786267
Pubmed	Genome-wide association study of intelligence: additive effects of novel brain expressed genes.	DEPDC5 CSMD2	1.07e-03	21	80	2	22449649
Pubmed	Analysis of FGF20-regulated genes in organ of Corti progenitors by translating ribosome affinity purification.	FAT3 TECTA	1.07e-03	21	80	2	32492250
Pubmed	A unified nomenclature for vertebrate olfactory receptors.	OR1N1 OR5AR1 OR51J1 OR13J1 OR5D13	1.19e-03	343	80	5	32295537
Pubmed	Odorant receptor expressed sequence tags demonstrate olfactory expression of over 400 genes, extensive alternate splicing and unequal expression levels.	OR1N1 OR5AR1 OR51J1 OR13J1 OR5D13	1.24e-03	346	80	5	14611657
Pubmed	Qualitative and quantitative analyses of protein phosphorylation in naive and stimulated mouse synaptosomal preparations.	PITPNM1 WDR7 TNC DLG2 ADCY9	1.25e-03	347	80	5	17114649
Pubmed	Functional synergy between cholecystokinin receptors CCKAR and CCKBR in mammalian brain development.	RELN TLE4	1.28e-03	23	80	2	25875176
Pubmed	Lhx2 regulates the timing of β-catenin-dependent cortical neurogenesis.	RELN TNC	1.28e-03	23	80	2	26371318
Pubmed	Interaction network of human early embryonic transcription factors.	ZFHX4 PHF12 TLE4 RREB1 TFAM	1.32e-03	351	80	5	38297188
Pubmed	Expression of Groucho/TLE proteins during pancreas development.	TLE2 TLE4	1.40e-03	24	80	2	18778483
Pubmed	Ccm3, a gene associated with cerebral cavernous malformations, is required for neuronal migration.	RELN TLE4	1.51e-03	25	80	2	24595293
Pubmed	Developmental abnormalities in cortical GABAergic system in mice lacking mGlu3 metabotropic glutamate receptors.	RELN GRM5	1.51e-03	25	80	2	31665922
Pubmed	Suppressor of Fused Is Critical for Maintenance of Neuronal Progenitor Identity during Corticogenesis.	RELN TLE4	1.64e-03	26	80	2	26387942
Pubmed	Activity-based chemical proteomics accelerates inhibitor development for deubiquitylating enzymes.	USP8 USP4	1.90e-03	28	80	2	22118674
Pubmed	CUL4-DDB1 ubiquitin ligase interacts with multiple WD40-repeat proteins and regulates histone methylation.	TLE2 WDR53	1.90e-03	28	80	2	17041588
Pubmed	Developmental gene expression profiling along the tonotopic axis of the mouse cochlea.	TNC TECTA	1.90e-03	28	80	2	22808246
Pubmed	EBF2 determines and maintains brown adipocyte identity.	RELN TFAM	2.04e-03	29	80	2	23499423
Pubmed	Large-scale characterization of HeLa cell nuclear phosphoproteins.	PITPNM1 BRAF PHF12 TLE4 DIDO1 RREB1 CXADR	2.05e-03	774	80	7	15302935
Pubmed	Systematic Analysis of Human Protein Phosphatase Interactions and Dynamics.	CNNM2 UBR4 EIF3L PRR14L INTS8 TFAM	2.09e-03	573	80	6	28330616
Pubmed	Identification and functional characterization of transcriptional activators in human cells.	KNTC1 BRAF ZFHX4 RREB1 TFAM	2.28e-03	398	80	5	35016035
GeneFamily	WD repeat domain containing	TULP4 WDR7 TLE2 TLE4 WDR90 WDR53	1.55e-04	262	56	6	362
GeneFamily	Ubiquitin specific peptidases	USP50 USP8 USP4	6.95e-04	56	56	3	366
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	TNC UBASH3B CSMD2 GRM5 RYR3	1.73e-05	178	80	5	a0ab20c588e7d43d0320d4779d9ab95c1c86e297
ToppCell	COVID-19-kidney-Epi_(Mes)\|kidney / Disease (COVID-19 only), tissue and cell type	RELN TNC TLE4 LAMA3 GRM5	1.78e-05	179	80	5	e7c9dc63f03d3f3746b51a7e3c8393089e2ceb7d
ToppCell	primary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_2-Inh_L1-3_VIP_ZNF322P1\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	FNDC1 RELN LAMA3 UBASH3B RYR3	1.93e-05	182	80	5	d3a037268f026eb2f84428b1821022503cef7756
ToppCell	Control-Stromal_mesenchymal-Lung_smooth_muscle-MatrixFB_->_Myofibroblast\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	FNDC1 TNC FAT3 LRP4 UBASH3B	1.98e-05	183	80	5	7eae9b3b4d1c9b135fa7cff348393d4adec474b4
ToppCell	LPS-IL1RA+antiTNF-Stromal_mesenchymal-Lung_smooth_muscle-MatrixFB_->_Myofibroblast\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	FNDC1 ZFHX4 TNC LRP4 UBASH3B	2.09e-05	185	80	5	3b2dfc8f4c87be516265dbecfc251276034d0efd
ToppCell	LA-13._Vascular_Smooth_Muscle\|LA / Chamber and Cluster_Paper	CNNM2 TNC FAT3 LAMA3 RYR3	2.25e-05	188	80	5	34e1b074a3995aa46ab194eb45115d76d1a5514d
ToppCell	Fetal_29-31_weeks-Mesenchymal-airway_smooth_muscle_cell\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	LINC00473 FNDC1 TNC UBASH3B RYR3	2.25e-05	188	80	5	4d1e5f85342ae550086609d7680e32730b78b5d2
ToppCell	LA-13._Vascular_Smooth_Muscle\|World / Chamber and Cluster_Paper	CNNM2 TNC FAT3 LAMA3 RYR3	2.31e-05	189	80	5	6b3e88751b95fc2173f2c3d5061ed632d0c5f01c
ToppCell	Brain_organoid-organoid_Kanton_Nature-Organoid-4M-Neuronal-ventral_progenitors_and_neurons_1\|Organoid-4M / Sample Type, Dataset, Time_group, and Cell type.	ZFHX4 TLE4 FAT3 GRM5 CXADR	2.37e-05	190	80	5	6e92c78799f34b31d098854503c796edb0dc7f80
ToppCell	Children_(3_yrs)-Epithelial\|Children_(3_yrs) / Lineage, Cell type, age group and donor	SNX25 LAMA3 DLG2 RP1 CXADR	2.43e-05	191	80	5	e432c6e1ae82dddf84314ce73d2b7a991630d905
ToppCell	10x3'2.3-week_17-19-Mesenchymal_osteo-stroma-osteoblast_precursor\|week_17-19 / cell types per 3 fetal stages;per 3',per 5'	FNDC1 ZFHX4 TNC FAT3 LRP4	2.68e-05	195	80	5	ec12cfb2fce44cc2de4e198ef5af075e626f0329
ToppCell	Smart-seq2-spleen_(Smart-seq2)-myeloid-myeloid_granulocytic-neutrophil\|spleen_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	FAT3 LRP4 IRAK3 CSMD2 RYR3	2.68e-05	195	80	5	d3755929ebbbf5e3afde44281e9056ddb614a291
ToppCell	Smart-seq2-spleen_(Smart-seq2)-myeloid-myeloid_granulocytic\|spleen_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	FAT3 LRP4 IRAK3 CSMD2 RYR3	2.68e-05	195	80	5	19853c654ac64b3ae3bc99841c6cb29c8aaba85c
ToppCell	Bronchial-NucSeq\|Bronchial / Cell types per location group and 10X technology with lineage, and cell group designations	BRAF SNX25 LRP4 DLG2 ADCY9	2.75e-05	196	80	5	ab53c742866945545a92e2e61850d63c80d9a2a6
ToppCell	10x3'2.3-week_14-16-Mesenchymal_osteo-stroma-osteoblast_precursor\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	FNDC1 ZFHX4 TNC FAT3 LRP4	2.89e-05	198	80	5	9d61483b0decac2fe90045b3474843360b2c49b3
ToppCell	10x5'v1-week_14-16-Mesenchymal_osteo-stroma-osteoblast_precursor\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	FNDC1 ZFHX4 TNC FAT3 LRP4	2.89e-05	198	80	5	bc9c9f2c87282b5ef8514773e065d2a6b5dde338
ToppCell	Neuronal-Inhibitory-iA-iA_1(SST_PAX6)-NMBR\|Neuronal / cells hierarchy compared to all cells using T-Statistic	RELN ZFHX4 TLE2 LAMA3 IRAK3	3.03e-05	200	80	5	862db57d043bdf3cb059fbfc8b29bc1eafdf64ec
ToppCell	Neuronal-Inhibitory-iA\|Neuronal / cells hierarchy compared to all cells using T-Statistic	RELN TLE2 LAMA3 IRAK3 UBASH3B	3.03e-05	200	80	5	5ef4a3dc18a44292184a59ced916183c0699b01e
ToppCell	Neuronal-Inhibitory-iA-iA_1(SST_PAX6)-NMBR--L1\|Neuronal / cells hierarchy compared to all cells using T-Statistic	RELN ZFHX4 TLE2 LAMA3 IRAK3	3.03e-05	200	80	5	a91345f268f13170c27309333603eb82400c9947
ToppCell	Neuronal-Inhibitory-iA-iA_1(SST_PAX6)-NMBR-\|Neuronal / cells hierarchy compared to all cells using T-Statistic	RELN ZFHX4 TLE2 LAMA3 IRAK3	3.03e-05	200	80	5	d416a7be1a4e6232fb58a9687774da24821f1fdd
ToppCell	frontal_cortex-Neuronal-GABAergic_neuron-Sncg-Sncg_Gpr50\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	KNTC1 SLC13A1 TNC CHRNA3	3.32e-05	101	80	4	6523c314166dcf66c3ed13c02ca4b886b068e5b8
ToppCell	primary_visual_cortex-Neuronal-GABAergic_neuron-Sncg-Sncg_Gpr50\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	KNTC1 SLC13A1 TNC CHRNA3	3.58e-05	103	80	4	d8965b338b90ddc0686ea0d94e9a330128566c39
ToppCell	COVID-19_Mild-Neu_4\|World / 5 Neutrophil clusters in COVID-19 patients	FAT3 CSMD2 ADCY9 CXADR	7.39e-05	124	80	4	5ef9eb806fb2c8ee5aae0a75503d244b08ee10d4
ToppCell	COVID-19-kidney-Technical/muscle_(Mes)\|COVID-19 / Disease (COVID-19 only), tissue and cell type	RELN KCNU1 CSMD2 GRM5	1.46e-04	148	80	4	d6ac5972267254651dfbe16bb4e9a62228093cc7
ToppCell	droplet-Liver-Hepatocytes-24m-Myeloid\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PITPNM1 SNX25 ARHGAP30 LRRK1	1.84e-04	157	80	4	ec433d2fe827abdb647be4176c231b7052482b6f
ToppCell	wk_15-18-Mesenchymal-Myofibro_&_SMC-Myofibro_2\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	TLE2 FAT3 LRP4 RNF43	1.84e-04	157	80	4	b9d04ee417c0d8ea0801d10f1c54e138587009fd
ToppCell	COVID-19-kidney-Technical/muscle_(Mes)\|kidney / Disease (COVID-19 only), tissue and cell type	RELN FAT3 CSMD2 GRM5	1.93e-04	159	80	4	5335cbcdeaf2bbd0268bbfe0e45c8c0d288e640d
ToppCell	TCGA-Liver-Primary_Tumor-Hepatocellular_Carcinoma-Hepatocellular_Carcinoma-7\|TCGA-Liver / Sample_Type by Project: Shred V9	KCNU1 SLC22A11 LAMA3 RNF43	1.93e-04	159	80	4	70288df54adab167c0f50675128619299077db11
ToppCell	facs-Marrow-B-cells-24m-Lymphocytic-precursor_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ZFHX4 FAT3 TECTA RYR3	1.97e-04	160	80	4	c381ec6be8cf887861cc18f831a20db42f953fe1
ToppCell	RV-13._Vascular_Smooth_Muscle\|World / Chamber and Cluster_Paper	IGHA1 TNC FAT3 LAMA3	1.97e-04	160	80	4	29c9b4770d0e73d59cffc7937b179484c76b6dcc
ToppCell	facs-Marrow-B-cells-24m-Lymphocytic-pre_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ZFHX4 FAT3 TECTA RYR3	1.97e-04	160	80	4	25c8f3d2a6d14ff0ca0b965fce89d3ff22f40585
ToppCell	343B-Epithelial_cells-Epithelial-H_(AT1)-\|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)	RELN LRP4 UBASH3B ITPRIPL1	2.02e-04	161	80	4	da9eecf919866a9c579d7a707a996cf335213134
ToppCell	343B-Epithelial_cells-Epithelial-H_(AT1)\|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)	RELN LRP4 UBASH3B ITPRIPL1	2.02e-04	161	80	4	d431625c32f59a6b552191f3adc5198bd16ad5cf
ToppCell	PND10-Endothelial-Endothelial_blood-vessel-Microvascular_EC-EPC-EPC_mature\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	KNTC1 TMEM150A PRIM2 TRIP13	2.12e-04	163	80	4	3efbbdc9cb2613bb76d8c2f07cd4ec1a2c51a622
ToppCell	normal_Lung-Fibroblasts-Myofibroblasts\|Fibroblasts / Location, Cell class and cell subclass	AXDND1 FNDC1 TNC DIRC1	2.17e-04	164	80	4	9b4a6007abae992db871d9f6f731d5af724de30d
ToppCell	facs-Lung-nan-3m-Epithelial-type_I_pneumocyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SKIDA1 LAMA3 RNF43 CXADR	2.27e-04	166	80	4	11b0ae82b3068ef91715dbdd49fe8e9791b4a480
ToppCell	facs-Lung-nan-3m-Epithelial-Alveolar_Epithelial_Type_1\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SKIDA1 LAMA3 RNF43 CXADR	2.27e-04	166	80	4	fcc1aec31ebd39432d4cb284dc8fadf34e3c566a
ToppCell	facs-Lung-3m-Epithelial-alveolar_epithelial-type_I_pneumocyte\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	LAMA3 RNF43 ADCY9 CXADR	2.32e-04	167	80	4	bebc2493a2ee41920b21c2b774a1c5a9619315c4
ToppCell	facs-Lung-3m-Epithelial-alveolar_epithelial-type_I_pneumocyte-type_1_alveolar_epithelial_cell\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	LAMA3 RNF43 ADCY9 CXADR	2.32e-04	167	80	4	9f2661729a2d58e17a9203a563d538c08a3dbbbc
ToppCell	tumor_Lymph_Node_/_Brain-Myeloid_cells-Pleural_Mac\|Myeloid_cells / Location, Cell class and cell subclass	SETMAR SNX25 DEPDC5 PRR14L	2.38e-04	168	80	4	8697b40b2ec2cce68ef3beb4792eb3eff29be053
ToppCell	droplet-Heart-HEART_(LV+RV_ONLY)-30m-Hematologic-fibroblast\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ZFHX4 ZNF575 ARHGAP30 WDR90	2.43e-04	169	80	4	15a9183c838cc6384d7f5dfeae3d30602964c9b3
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_S-high\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	KNTC1 LAMA3 TRIP13 CHRNA3	2.43e-04	169	80	4	121768fc51fc3441ec725346a1bbe29e21d05971
ToppCell	facs-Lung-24m-Hematologic-lymphocytic-CD8-positive,_alpha-beta_T_cell-CD8-positive,_alpha-beta_T_cell_l5\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	SLX4IP DLG2 TFAM RYR3	2.43e-04	169	80	4	a388e53deac861a185c31e9cceddae7bcb344700
ToppCell	facs-Brain_Non-Myeloid-Striatum_-18m-Epithelial-neuronal_stem_cell\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KNTC1 PRIM2 WDR90 TRIP13	2.60e-04	172	80	4	35c20de4db47dbf31c857d23c7a25cd7f95c085c
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Immune-Lymphocytic_B\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	IGHA1 ARHGAP30 LRRK1 ITPRIPL1	2.66e-04	173	80	4	62ba49c1c16760a8c6cde0cc44e068f94386946a
ToppCell	PND10-Immune-Immune_Myeloid-Monocytic-Macrophage-iMON-iMON_G2M\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	PITPNM1 SLX4IP ARHGAP30 WDR90	2.84e-04	176	80	4	90f8bb11f339f67f08692a0c33dd420f5cda2861
ToppCell	368C-Epithelial_cells-Epithelial-B_(AT2)-\|368C / Donor, Lineage, Cell class and subclass (all cells)	SNX25 LAMA3 WDR90 RNF43	2.90e-04	177	80	4	ac8f774596068e66c0a9ea8a318be0ce5f5df834
ToppCell	368C-Epithelial_cells-Epithelial-B_(AT2)\|368C / Donor, Lineage, Cell class and subclass (all cells)	SNX25 LAMA3 WDR90 RNF43	2.90e-04	177	80	4	d9c4a93b0e04a13bf39992dd1c1ec8df2c5f89fe
ToppCell	Primary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_2-Inh_L1-3_VIP_ZNF322P1\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	FNDC1 RELN LAMA3 RYR3	2.96e-04	178	80	4	2a36475c260088f69f3b8c282d910e5eaa5c5c2d
ToppCell	TCGA-Liver-Primary_Tumor-Hepatocellular_Carcinoma-Hepatocellular_Carcinoma-1\|TCGA-Liver / Sample_Type by Project: Shred V9	ARHGEF10 LRRK1 UBASH3B CCDC148	2.96e-04	178	80	4	51c59dabf2d7aef1b1964f6f766d5ec07ef90f5a
ToppCell	facs-Brain_Non-Myeloid-Hippocampus-3m-Neuronal-neuron\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RELN FAT3 BARHL2 CCDC148	3.03e-04	179	80	4	479116ac65488c60104a053530830763ec1f95b2
ToppCell	facs-Brain_Non-Myeloid-Hippocampus-3m-Neuronal-nan\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RELN FAT3 BARHL2 CCDC148	3.03e-04	179	80	4	1dfc0cb8b369aef35c59f3d4c52603dc9f3728c1
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_S-high\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	KNTC1 PRIM2 LAMA3 TRIP13	3.03e-04	179	80	4	88d44b04eb5c079531db663ed98ddb20b60feb9a
ToppCell	facs-Brain_Non-Myeloid-Hippocampus-3m-Neuronal\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RELN FAT3 BARHL2 CCDC148	3.03e-04	179	80	4	69a1b3b05c921de6343ffe6ad998aa2b804312a7
ToppCell	LPS-IL1RA-Stromal_mesenchymal-Lung_smooth_muscle-MatrixFB_->_Myofibroblast\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	FNDC1 ZFHX4 TNC LRP4	3.03e-04	179	80	4	02c90d8306016365ed811f0c63cfb3ac7b85464c
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_2\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	FAT3 DLG2 UBASH3B GRM5	3.16e-04	181	80	4	6956ecd6264f7469a25e555673bce4eb97d28f7a
ToppCell	5'-Adult-LargeIntestine-Mesenchymal-fibroblastic-Stromal_3_(C7+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	FNDC1 ZFHX4 TNC DLG2	3.22e-04	182	80	4	3dfa9187e9d2bab1d199079d29209c4648220ada
ToppCell	3'-GW_trimst-1.5-SmallIntestine-Neuronal-neuron_precursor-cycling_neuroblast\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	DLG2 DEPDC5 CSMD2 CHRNA3	3.22e-04	182	80	4	e6968e0bd9cef92052d04ac54e2dd746b37623f6
ToppCell	Children_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2-D046\|Children_(3_yrs) / Lineage, Cell type, age group and donor	SNX25 LAMA3 DLG2 RNF43	3.29e-04	183	80	4	6847c1252d6bb105524f812658112517fd351eab
ToppCell	LPS_only-Stromal_mesenchymal-Lung_smooth_muscle-MatrixFB_->_Myofibroblast\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	FNDC1 ZFHX4 TNC LRP4	3.29e-04	183	80	4	12daaea821e49bc94a01e2496331e92a80d27339
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RELN ZFHX4 FAT3 RYR3	3.36e-04	184	80	4	2cbed6462fea2622871bb7e49b0df3d984239281
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RELN ZFHX4 FAT3 RYR3	3.36e-04	184	80	4	ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RELN ZFHX4 FAT3 RYR3	3.36e-04	184	80	4	2b19a8c5f823e00812908b23e66bb4e563278aff
ToppCell	LPS-antiTNF-Stromal_mesenchymal-Lung_smooth_muscle-MatrixFB_->_Myofibroblast\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	FNDC1 ZFHX4 TNC LRP4	3.43e-04	185	80	4	6712512100ccef456d2e2bd201d0987986c92ac9
ToppCell	Primary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic-i_Gaba_2\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	RELN LAMA3 IRAK3 UBASH3B	3.43e-04	185	80	4	cefd81adb480c027545a5c78dcd05669783717f4
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_2-Inh_L1-3_VIP_ZNF322P1\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	FNDC1 LAMA3 LRP4 RYR3	3.43e-04	185	80	4	0b5a0df58ae2ad8261f40f152775747af4f3937a
ToppCell	Fetal_29-31_weeks-Mesenchymal-airway_smooth_muscle_cell-D088\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	LINC00473 TNC UBASH3B RYR3	3.43e-04	185	80	4	e58a009aaf342be019a909747b1895d5987d4daf
ToppCell	Mesenchymal_cells-Osteo-CAR\|World / Lineage and Cell class	ZFHX4 TNC TLE2 LRP4	3.43e-04	185	80	4	16f1588893d09c864e0cb4f837a1b972a1a57baa
ToppCell	Primary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5-Inh_L1_LAMP5_NDNF\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	FNDC1 RELN LAMA3 IRAK3	3.50e-04	186	80	4	310d16f4e5cffee3ea6d7635508c513a3b92131e
ToppCell	primary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_2\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	RELN LAMA3 IRAK3 UBASH3B	3.57e-04	187	80	4	ae2ee6f8e5c37cb88a67f3e742cf86e57657bfaf
ToppCell	COPD-Epithelial-ATII\|Epithelial / Disease state, Lineage and Cell class	TNC SNX25 DLG2 RMC1	3.57e-04	187	80	4	030af361f8bdcd0aff4ec1922702833325cf74d8
ToppCell	5'-Airway_Nasal-Epithelial-Epithelial_transtional-secretory-club_cell-Club_(nasal)-Club_(nasal)_L.0.2.3.1\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	TNC RNF213 PRR14L LRRK1	3.57e-04	187	80	4	a6a112689d1c9049f57935ad9d2f4955538427de
ToppCell	10x3'2.3-week_14-16-Mesenchymal_myocytic-stroma-muscle_stem_cell\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	FNDC1 ZFHX4 TNC FAT3	3.64e-04	188	80	4	de6f4889e0c5f39fbbaefd85526f645c6afa09d5
ToppCell	cellseq2-Endothelial-Endothelial_Vascular-Endothelial_large_blood_vessel-VEC\|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	BRAF SNX25 LRRK1 WDR53	3.72e-04	189	80	4	bccb3481ffed597c845fe860da658505316105b5
ToppCell	(1)_Osterolineage_cells-(10)_OLC-1\|World / Cell class and subclass of bone marrow stroma cells in homeostatis	ZFHX4 TNC FAT3 LRP4	3.72e-04	189	80	4	46c5b975fb9d33017f2d9b7770d45a8bdf95baa2
ToppCell	Control-Stromal_mesenchymal-Lung_smooth_muscle\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	FNDC1 TNC FAT3 LRP4	3.72e-04	189	80	4	45e588b2a4ad9e3ff74e22d9d627ed3571f3b8b8
ToppCell	wk_15-18-Mesenchymal-Myofibro_&_SMC-Myofibro_1\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	TLE2 FAT3 LRP4 RNF43	3.79e-04	190	80	4	d24af6af3271e34afab744352afd28be8a7cc5c3
ToppCell	Mesenchymal-airway_smooth_muscle_cell\|World / Lineage, Cell type, age group and donor	LINC00473 FNDC1 TNC RYR3	3.79e-04	190	80	4	645e56b02edc3702c7db917b8ecd5eed0decaf71
ToppCell	Control-Stromal_mesenchymal\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	FNDC1 TNC FAT3 LRP4	3.87e-04	191	80	4	14057205ddb9b4bbc582d1358d13cf36d979a61b
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5-Inh_L1_LAMP5_NDNF\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	RELN TLE2 LAMA3 IRAK3	3.87e-04	191	80	4	7b386512284dfaa0e95358b28ee82632ee965e64
ToppCell	10x3'2.3-week_12-13-Mesenchymal_osteo-stroma-osteoblast_precursor\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	FNDC1 ZFHX4 TNC FAT3	3.87e-04	191	80	4	98b907f8fa024cf32e462323b782c5a371327bbd
ToppCell	(1)_Osterolineage_cells-(10)_OLC-1\|(1)_Osterolineage_cells / Cell class and subclass of bone marrow stroma cells in homeostatis	TNC TLE2 FAT3 LRP4	3.87e-04	191	80	4	78ad7c555409ce1391bce406bc0f3ef575329ece
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5-Inh_L1_LAMP5_NDNF\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	RELN TLE2 LAMA3 UBASH3B	3.87e-04	191	80	4	fa50a3c7ff86e1ee07100da1ace0b0fa1b0ab26b
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_2\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	RELN LAMA3 IRAK3 UBASH3B	3.95e-04	192	80	4	3abee376c37c3646da33ac381aa63d50a01607a6
ToppCell	Adult-Immune-alveolar_macrophage_(MARCO_positive)-D175\|Adult / Lineage, Cell type, age group and donor	IRAK3 ARHGAP30 UBASH3B RREB1	3.95e-04	192	80	4	733491e932350e3c216a626cc49c3cd3fe970a82
ToppCell	(1)_Osterolineage_cells\|World / Cell class and subclass of bone marrow stroma cells in homeostatis	ZFHX4 TNC FAT3 LRP4	4.02e-04	193	80	4	035eeea9f77c4bf9cd85f07fa791b6c857be76b5
ToppCell	Children_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2-D032\|Children_(3_yrs) / Lineage, Cell type, age group and donor	SNX25 LAMA3 DLG2 ADCY9	4.10e-04	194	80	4	97534c8bba895a7913665e03ae4e5c4a6ad71daf
ToppCell	10x5'v1-week_14-16-Mesenchymal_myocytic-stroma-myofibroblast\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	ZFHX4 TNC FAT3 LRP4	4.18e-04	195	80	4	30ed961151b8b1f6ce37f06c9a061519f01c2864
ToppCell	facs-Brain_Myeloid-Hippocampus\|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	USP8 SLC39A10 UBASH3B ITPRIPL1	4.18e-04	195	80	4	a1478021a3ed0e779716393124ca2a7770c433b7
ToppCell	human_hepatoblastoma-Inflammatory_Monocytes\|human_hepatoblastoma / Sample and Cell Type and Tumor Cluster (all cells)	IRAK3 ARHGAP30 LRRK1 UBASH3B	4.18e-04	195	80	4	ba7f85e5307d96ac5ad7c952f8d094db9ca1790c
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	ZFHX4 FAT3 CXADR CCDC148	4.27e-04	196	80	4	c7136b1c83bcf907eec3b02b151fa061298b6672
ToppCell	10x5'v1-week_17-19-Mesenchymal_osteo-stroma-osteoblast_precursor\|week_17-19 / cell types per 3 fetal stages;per 3',per 5'	FNDC1 ZFHX4 TNC LRP4	4.27e-04	196	80	4	57df2a57b35be9851ac0b1e5731baa53052511f0
ToppCell	distal-3-Epithelial-Ionocyte\|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	ZNF575 DLG2 RNF43 CHRNA3	4.27e-04	196	80	4	6ed146481dd04fb271eadc47d68eb3ae38986db6
ToppCell	COVID-19-lung-Macrophage_LDB2hi_OSMRhi_YAP1hi\|COVID-19 / Disease (COVID-19 only), tissue and cell type	RNF213 IRAK3 ARHGAP30 UBASH3B	4.35e-04	197	80	4	e42910a653a1b5bd90c090e9665a84871ed2873f
ToppCell	10x5'v1-week_12-13-Mesenchymal_osteo-stroma-early_osteoblast\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	ZFHX4 TNC FAT3 LRP4	4.35e-04	197	80	4	2ca5ebb708935a90b12b8e98a22ae2d664ed002e
ToppCell	distal-Epithelial-Ionocyte\|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	ZNF575 DLG2 RNF43 CHRNA3	4.35e-04	197	80	4	11a5d2db2561d045756980ead61e1211c7dda100
ToppCell	distal-Epithelial-Ionocyte-3\|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	ZNF575 DLG2 RNF43 CHRNA3	4.35e-04	197	80	4	7a2cd970fe0866057999e40d15367b2b3324ae59
ToppCell	Fetal_brain-fetalBrain_Zhong_nature-GW19-Macroglial-Astrocyte\|GW19 / Sample Type, Dataset, Time_group, and Cell type.	ARHGEF10 TNC LRP4 RNF213	4.43e-04	198	80	4	bfad1c51cf884ff7ce89f8278820800582541dc7
ToppCell	distal-3-mesenchymal-Fibromyocyte\|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	LINC00473 FNDC1 TNC CSMD2	4.43e-04	198	80	4	dc93886439a378a0c71e99acb8081bfb6b6d467b
ToppCell	10x3'2.3-week_17-19-Mesenchymal_osteo-stroma\|week_17-19 / cell types per 3 fetal stages;per 3',per 5'	FNDC1 ZFHX4 TNC FAT3	4.43e-04	198	80	4	1f956e369e00d37835095a001db4b62a79014532
Disease	Nail Diseases	TINF2 LAMA3	6.55e-06	2	76	2	C0027339
Disease	Autosomal Dominant Lateral Temporal Lobe Epilepsy	RELN DEPDC5	1.96e-05	3	76	2	C1838062
Disease	colorectal adenoma	FAT3 DLG2 CSMD2	8.47e-05	33	76	3	EFO_0005406
Disease	rhegmatogenous retinal detachment	FAT3 GFUS	9.75e-05	6	76	2	EFO_0005240
Disease	retinal detachment, retinal break	AXDND1 FAT3 GRM5	1.01e-04	35	76	3	EFO_0005773, EFO_0010698
Disease	retinal detachment	FAT3 GRM5	1.36e-04	7	76	2	EFO_0005773
Disease	immunoglobulin isotype switching measurement	IGHA1 UBR4 LAMA3	2.02e-04	44	76	3	EFO_0010128
Disease	pulse pressure measurement	USP50 FNDC1 CNNM2 ZFHX4 WDR7 FAT3 SLX4IP RNF213 SLC39A10 RREB1 INTS8 DIRC1	2.19e-04	1392	76	12	EFO_0005763
Disease	schizophrenia, anorexia nervosa	CNNM2 DLG2 CHRNA3	2.61e-04	48	76	3	MONDO_0005090, MONDO_0005351
Disease	osteoarthritis	USP50 USP8 RELN DLG2 RP1	2.76e-04	222	76	5	MONDO_0005178
Disease	age at onset, multiple sclerosis	AXDND1 RELN	2.91e-04	10	76	2	EFO_0004847, MONDO_0005301
Disease	fish consumption measurement	DLG2 DEPDC5 GRM5	6.11e-04	64	76	3	EFO_0010139
Disease	glycerate measurement	SLC23A1 RYR3	6.73e-04	15	76	2	EFO_0021029
Disease	schizophrenia (implicated_via_orthology)	RELN CNNM2 GRM5	7.30e-04	68	76	3	DOID:5419 (implicated_via_orthology)
Disease	serum alanine aminotransferase measurement, response to combination chemotherapy	RNF213 DEPDC5 CSMD2	8.27e-04	71	76	3	EFO_0004735, EFO_0007965
Disease	uric acid measurement	CNNM2 FAT3 SLC22A11 UBASH3B RREB1 TFAM ADCY9	9.94e-04	610	76	7	EFO_0004761
Disease	insomnia measurement	CNNM2 DLG2 WDR90 RREB1 GRM5 CCDC148	9.98e-04	443	76	6	EFO_0007876
Disease	Pancreatic carcinoma	BRAF RNF43	1.09e-03	19	76	2	C0235974
Disease	household income	AXDND1 TLE4 BARHL2 USP4 DIRC1	1.14e-03	304	76	5	EFO_0009695
Disease	hypertension	USP8 CNNM2 RNF213 GRM5 RNF43	1.19e-03	307	76	5	EFO_0000537
Disease	cholangiocarcinoma (is_implicated_in)	BRAF RNF43	1.46e-03	22	76	2	DOID:4947 (is_implicated_in)
Disease	Cholangiocarcinoma	BRAF RNF43	2.04e-03	26	76	2	C0206698
Disease	mean corpuscular hemoglobin concentration	KNTC1 CNNM2 RREB1 GFUS TRIP13 INTS8 SLC23A1 RNF43 ADCY9	2.11e-03	1105	76	9	EFO_0004528
Disease	Acute Confusional Senile Dementia	RELN TPP1 TFAM	2.16e-03	99	76	3	C0546126
Disease	Alzheimer's Disease, Focal Onset	RELN TPP1 TFAM	2.16e-03	99	76	3	C0750900
Disease	Alzheimer Disease, Early Onset	RELN TPP1 TFAM	2.16e-03	99	76	3	C0750901
Disease	Presenile dementia	RELN TPP1 TFAM	2.16e-03	99	76	3	C0011265
Disease	Alzheimer Disease, Late Onset	RELN TPP1 TFAM	2.16e-03	99	76	3	C0494463
Disease	Familial Alzheimer Disease (FAD)	RELN TPP1 TFAM	2.22e-03	100	76	3	C0276496
Disease	Alzheimer's Disease	RELN TPP1 TFAM	2.28e-03	101	76	3	C0002395
Disease	susceptibility to rheumatic fever measurement	RELN RYR3	2.37e-03	28	76	2	EFO_0008416
Disease	lung small cell carcinoma (is_implicated_in)	LAMA3 CHRNA3	2.37e-03	28	76	2	DOID:5409 (is_implicated_in)
Disease	Neoplasm of uncertain or unknown behavior of ovary	BRAF RNF43	2.54e-03	29	76	2	C0496920

Protein segments in the cluster

Peptide	Gene	Start	Entry
EDFSLYACASPKTPI	BRAF	741	P15056
LLPAYSSPVIICATS	ARHGEF10	166	O15013
SLECPYPDLKSSILS	CCDC148	216	Q8NFR7
IFAIAFSAYPLTKCP	CSMD2	2281	Q7Z408
PPAIFKSSCKIDVTY	CHRNA3	151	P32297
LCPEKESTSALPAYT	ADGRG4	1376	Q8IZF6
LSTYELPSCYPTKDL	C7orf31	406	Q8N865
LPSCYPTKDLTSIYD	C7orf31	411	Q8N865
LPLVEKFSYCSLSTP	AP4E1	861	Q9UPM8
CIKPVTSFYDIPASA	INTS8	491	Q75QN2
SLTTPACLPLTTDYF	DEPDC5	746	O75140
ESALCIPSSPKYDTL	GRM5	1186	P41594
KPLYTPSSSFGVSSC	LAMA3	3136	Q16787
CSYILLDSPDPSKHL	LRRK1	221	Q38SD2
ELFSYSCPKFLSPVV	EIF3L	411	Q9Y262
CPLTFLLSAPQSYLS	OR51J1	176	Q9H342
SKRYPLESTSLPYCS	KNTC1	1226	P50748
SCLSTCIFPDKTTYP	GFUS	111	Q13630
PPSLELETIFKCYLA	KCNU1	371	A8MYU2
YFAEDPPTSLKSFRC	IRAK3	451	Q9Y616
LSTLDICYTPTFVPL	OR13J1	66	Q8NGT2
FVYLELPAAAKTPCT	RELN	1181	P78509
PPSAAAIFKIYLSCL	TRIP13	321	Q15645
DYTPFSCLKIILSNP	PRIM2	361	P49643
KYDFKLSLPPSTTSC	ITPRIPL1	336	Q6GPH6
LASSCPRLYAPLISF	LINC00473	126	A8K010
TYLNKDPSAPCSLTD	FNDC1	1616	Q4ZHG4
YSKILPSLISSLDFC	AXDND1	601	Q5T1B0
TAYLPCKFTLSPEDQ	CXADR	36	P78310
DCSPAFIPSSYSVKV	FAT3	931	Q8TDW7
TFTCTAAYPESKTPL	IGHA1	201	P01876
PSKYPLCSADAAVST	DIDO1	1241	Q9BTC0
YVSLCPDSSVLTSPL	ADCY9	936	O60503
SKPLAACAPYSTSVS	BARHL2	151	Q9NY43
PVECDKSFLLSAPYS	DLG2	366	Q15700
LEPSIISDTCFYKPI	DIRC1	56	Q969H9
TCLTIYKAELFPTPV	SLC22A11	446	Q9NSA0
NPLYILIPSTLCTSF	SLC13A1	511	Q9BZW2
ANSPISTDLFTYLCP	SLC39A10	351	Q9ULF5
PASIADKVFCSLPYS	PRR14L	1866	Q5THK1
TILFLYCVPNPKTSS	OR5D13	256	Q8NGL4
SSLCKAYFRELPDPL	ARHGAP30	91	Q7Z6I6
RLATPPSLDFCYDSK	RP1	1531	P56715
DTTYACTFLPLPIVS	MOXD2P	206	A6NHM9
GTLFSAYLCPPSIAS	OR1N1	251	Q8NGS0
SLALSRPSAPSLCYF	TMEM179B	51	Q7Z7N9
ISKCGSYPPESCLFS	TMEM150A	66	Q86TG1
LCQSEALYAFLSPSP	SNX25	611	Q9H3E2
NVLYSCDFSEKTPPT	PHF12	866	Q96QT6
AFPSDPAYFRSLLCS	SKIDA1	206	Q1XH10
LSSDFDPLVYCSPKG	RNF43	501	Q68DV7
AFLPFDSSLYCPVEK	SETMAR	296	Q53H47
LASCPKKPVSSYLRF	TFAM	46	Q00059
IPPLLALSCSDTYIS	OR5AR1	181	Q8NGP9
YFAECAESSLPPSAK	SLX4IP	146	Q5VYV7
TFPASYPVSKLLDCV	CNNM2	386	Q9H8M5
FPSEFSYTLLKTCPE	TECTA	731	O75443
SLYCPEALTAFPTVT	PITPNM1	841	O00562
PEEALSPSYLTVCLK	RNF213	836	Q63HN8
SKLTLPPRLCSYLST	TULP4	396	Q9NRJ4
LSPYISDPALKLFQC	ZFHX4	866	Q86UP3
APRTTYLASCKAFTP	WDR90	1071	Q96KV7
KVSVTFDPFCYLTLP	USP4	466	Q13107
YIPICPVFKGFSSSS	SLC23A1	561	Q9UHI7
NISFLSPSSLVPYDC	RREB1	916	Q92766
KPLACLLLSLESFYP	RMC1	531	Q96DM3
SAPACYALAISPDSK	TLE4	576	Q04727
FTSHCLYFLSSPLKP	RYR3	2871	Q15413
TKFDTLIPTLCEYLP	TINF2	416	Q9BSI4
PDCDKAFSYPSKLAT	ZNF575	66	Q86XF7
FTTIGLLYPFPKDCS	TNC	1971	P24821
VFSLPIPSKYECSLR	USP50	211	Q70EL3
YASSALSPCLTAPKS	SYNGR4	211	O95473
SVLFSPSCPTKLYAS	WDR53	56	Q7Z5U6
CKFSAPLPLELYTSS	UBASH3B	156	Q8TF42
CSLLTYPSEDFDLPK	TOGARAM1	496	Q9Y4F4
DALSPTFYFLLPSSK	UBR4	2031	Q5T4S7
SAPACYALAVSPDAK	TLE2	546	Q04725
YIYKLPASCLPASDS	WDR7	281	Q9Y4E6
PTCYPKAEISRLSAS	USP8	746	P40818
FALILSGKCSYSPEP	TPP1	11	O14773
KTCDPSPETYLLFSS	LRP4	1346	O75096