Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionryanodine-sensitive calcium-release channel activity

RYR1 RYR2 RYR3

9.08e-0741233GO:0005219
GeneOntologyMolecularFunctioncalcium-induced calcium release activity

RYR1 RYR2 RYR3

4.50e-0661233GO:0048763
GeneOntologyMolecularFunctiontransporter activity

TMC1 TMC2 ABCA12 SLC19A2 XKR8 FLVCR2 MAGT1 KCNB2 AQP6 SLC2A4 RYR1 RYR2 RYR3 SLC7A3 KCNB1 SLC35A4 SLC2A6 DISP2 KCNK6 SLC38A3 PLTP

3.79e-05128912321GO:0005215
GeneOntologyMolecularFunctiontransmembrane transporter activity

TMC1 TMC2 ABCA12 SLC19A2 FLVCR2 MAGT1 KCNB2 AQP6 SLC2A4 RYR1 RYR2 RYR3 SLC7A3 KCNB1 SLC35A4 SLC2A6 DISP2 KCNK6 SLC38A3

1.08e-04118012319GO:0022857
GeneOntologyMolecularFunctionganglioside GM1 binding

PSAP RTN4R

1.12e-0431232GO:1905573
GeneOntologyMolecularFunctionganglioside GT1b binding

PSAP RTN4R

1.12e-0431232GO:1905576
GeneOntologyMolecularFunctionPyrin domain binding

NLRP7 NLRP2

1.12e-0431232GO:0032090
GeneOntologyMolecularFunctionintracellularly gated calcium channel activity

RYR1 RYR2 RYR3

1.74e-04181233GO:0015278
GeneOntologyMolecularFunctionceramide binding

PSAP RTN4R PLTP

2.41e-04201233GO:0097001
GeneOntologyMolecularFunctionG protein-coupled receptor activity

OR4N2 GPR31 OR4N4 OR5L1 ADGRB3 SSTR2 OR2L13 OR1L3 EDNRB ADRA1B OR14A2 OR1Q1 MRGPRX1 OR5L2 OR7A10

3.54e-0488412315GO:0004930
GeneOntologyMolecularFunctionvoltage-gated monoatomic cation channel activity

TMC1 TMC2 KCNB2 RYR1 KCNB1 KCNK6

3.60e-041521236GO:0022843
GeneOntologyMolecularFunctionganglioside binding

PSAP RTN4R

3.72e-0451232GO:0035594
GeneOntologyMolecularFunctionmetal ion transmembrane transporter activity

TMC1 TMC2 MAGT1 KCNB2 RYR1 RYR2 RYR3 KCNB1 KCNK6 SLC38A3

6.13e-0446512310GO:0046873
GeneOntologyMolecularFunctionligand-gated calcium channel activity

RYR1 RYR2 RYR3

9.04e-04311233GO:0099604
GeneOntologyMolecularFunctionvoltage-gated monoatomic ion channel activity

TMC1 TMC2 KCNB2 RYR1 KCNB1 KCNK6

9.30e-041821236GO:0005244
GeneOntologyMolecularFunctionvoltage-gated channel activity

TMC1 TMC2 KCNB2 RYR1 KCNB1 KCNK6

9.84e-041841236GO:0022832
GeneOntologyMolecularFunctionintracellularly ligand-gated monoatomic ion channel activity

RYR1 RYR2 RYR3

1.09e-03331233GO:0005217
GeneOntologyMolecularFunctiongated channel activity

TMC1 TMC2 KCNB2 RYR1 RYR2 RYR3 KCNB1 KCNK6

1.10e-033341238GO:0022836
GeneOntologyMolecularFunctionsphingolipid binding

PSAP RTN4R PLTP

1.19e-03341233GO:0046625
GeneOntologyMolecularFunctioncalcium channel activity

TMC1 TMC2 RYR1 RYR2 RYR3

1.22e-031291235GO:0005262
GeneOntologyMolecularFunctionmonoatomic cation channel activity

TMC1 TMC2 KCNB2 RYR1 RYR2 RYR3 KCNB1 KCNK6

1.30e-033431238GO:0005261
GeneOntologyMolecularFunctionaspartic-type endopeptidase inhibitor activity

NLRP7 NLRP2

1.32e-0391232GO:0019828
GeneOntologyMolecularFunctionolfactory receptor activity

OR4N2 OR4N4 OR5L1 OR2L13 OR1L3 OR14A2 OR1Q1 OR5L2 OR7A10

1.41e-034311239GO:0004984
GeneOntologyMolecularFunctiontransmembrane signaling receptor activity

OR4N2 GPR31 OR4N4 OR5L1 RTN4R ADGRB3 SSTR2 OR2L13 OR1L3 EDNRB ADRA1B OR14A2 TIE1 OR1Q1 MRGPRX1 MERTK OR5L2 OR7A10

1.58e-03135312318GO:0004888
GeneOntologyMolecularFunctioninorganic cation transmembrane transporter activity

TMC1 TMC2 MAGT1 KCNB2 SLC2A4 RYR1 RYR2 RYR3 KCNB1 KCNK6 SLC38A3

1.72e-0362712311GO:0022890
GeneOntologyMolecularFunctioninterleukin-1 binding

NLRP7 NLRP2

2.39e-03121232GO:0019966
GeneOntologyMolecularFunctioncalcium ion transmembrane transporter activity

TMC1 TMC2 RYR1 RYR2 RYR3

2.45e-031511235GO:0015085
GeneOntologyMolecularFunctioninorganic molecular entity transmembrane transporter activity

TMC1 TMC2 MAGT1 KCNB2 AQP6 SLC2A4 RYR1 RYR2 RYR3 KCNB1 KCNK6 SLC38A3

2.51e-0375812312GO:0015318
GeneOntologyMolecularFunctionmonoatomic cation transmembrane transporter activity

TMC1 TMC2 MAGT1 KCNB2 SLC2A4 RYR1 RYR2 RYR3 KCNB1 KCNK6 SLC38A3

2.69e-0366412311GO:0008324
GeneOntologyMolecularFunctionprofilin binding

CYFIP1 FMNL1

2.81e-03131232GO:0005522
GeneOntologyMolecularFunctionglycosphingolipid binding

PSAP RTN4R

2.81e-03131232GO:0043208
GeneOntologyMolecularFunctionvoltage-gated calcium channel activity

TMC1 TMC2 RYR1

2.85e-03461233GO:0005245
GeneOntologyMolecularFunctionazole transmembrane transporter activity

SLC19A2 SLC38A3

3.26e-03141232GO:1901474
GeneOntologyCellularComponentsarcolemma

LAMA2 SLC2A4 RYR1 RYR2 RYR3 ADRA1B KCNB1

1.27e-041901227GO:0042383
GeneOntologyCellularComponentstereocilium tip

TMC1 TMC2 ESPNL

2.75e-04221223GO:0032426
DomainRyanodine_rcpt

RYR1 RYR2 RYR3

2.52e-0731193IPR003032
DomainRyanrecept_TM4-6

RYR1 RYR2 RYR3

2.52e-0731193IPR009460
DomainRyR

RYR1 RYR2 RYR3

2.52e-0731193PF02026
DomainRR_TM4-6

RYR1 RYR2 RYR3

2.52e-0731193PF06459
DomainRyan_recept

RYR1 RYR2 RYR3

2.52e-0731193IPR013333
DomainRIH_assoc-dom

RYR1 RYR2 RYR3

4.97e-0661193IPR013662
DomainIns145_P3_rec

RYR1 RYR2 RYR3

4.97e-0661193PF08709
DomainRIH_assoc

RYR1 RYR2 RYR3

4.97e-0661193PF08454
DomainRIH_dom

RYR1 RYR2 RYR3

4.97e-0661193IPR000699
DomainIns145_P3_rcpt

RYR1 RYR2 RYR3

4.97e-0661193IPR014821
DomainRyanodine_recept-rel

RYR1 RYR2 RYR3

4.97e-0661193IPR015925
Domain-

RYR1 RYR2 RYR3

4.97e-06611931.25.10.30
DomainRYDR_ITPR

RYR1 RYR2 RYR3

4.97e-0661193PF01365
DomainMIR

RYR1 RYR2 RYR3

2.93e-05101193PF02815
DomainMIR_motif

RYR1 RYR2 RYR3

2.93e-05101193IPR016093
DomainMIR

RYR1 RYR2 RYR3

2.93e-05101193PS50919
DomainMIR

RYR1 RYR2 RYR3

2.93e-05101193SM00472
DomainK_chnl_volt-dep_Kv2

KCNB2 KCNB1

4.03e-0521192IPR003973
DomainKv2channel

KCNB2 KCNB1

4.03e-0521192PF03521
DomainGPCR_Rhodpsn_7TM

OR4N2 GPR31 OR4N4 OR5L1 SSTR2 OR2L13 OR1L3 EDNRB ADRA1B OR1Q1 MRGPRX1 OR5L2 OR7A10

3.45e-0467011913IPR017452
Domain7tm_1

OR4N2 GPR31 OR4N4 OR5L1 SSTR2 OR2L13 OR1L3 EDNRB ADRA1B OR1Q1 MRGPRX1 OR5L2 OR7A10

3.81e-0467711913PF00001
DomainG_PROTEIN_RECEP_F1_1

OR4N2 GPR31 OR4N4 OR5L1 SSTR2 OR2L13 OR1L3 EDNRB ADRA1B OR1Q1 MRGPRX1 OR5L2 OR7A10

4.26e-0468511913PS00237
DomainG_PROTEIN_RECEP_F1_2

OR4N2 GPR31 OR4N4 OR5L1 SSTR2 OR2L13 OR1L3 EDNRB ADRA1B OR1Q1 MRGPRX1 OR5L2 OR7A10

4.63e-0469111913PS50262
DomainGPCR_Rhodpsn

OR4N2 GPR31 OR4N4 OR5L1 SSTR2 OR2L13 OR1L3 EDNRB ADRA1B OR1Q1 MRGPRX1 OR5L2 OR7A10

4.69e-0469211913IPR000276
DomainDUF3398

DOCK8 DOCK6

5.94e-0461192PF11878
DomainDOCK_C/D_N

DOCK8 DOCK6

5.94e-0461192IPR021816
DomainIon_trans_dom

KCNB2 RYR1 RYR2 RYR3 KCNB1

8.15e-041141195IPR005821
DomainIon_trans

KCNB2 RYR1 RYR2 RYR3 KCNB1

8.15e-041141195PF00520
DomainTMC

TMC1 TMC2

1.10e-0381192PF07810
DomainTMC

TMC1 TMC2

1.10e-0381192IPR012496
DomainARM-type_fold

DOCK8 RALGAPA2 RYR3 ARFGEF3 ELMO3 HEATR6 LRBA FMNL1

1.48e-033391198IPR016024
DomainDHR-1_domain

DOCK8 DOCK6

2.13e-03111192IPR027007
DomainDHR_2

DOCK8 DOCK6

2.13e-03111192PS51651
DomainDHR_1

DOCK8 DOCK6

2.13e-03111192PS51650
DomainDHR-2

DOCK8 DOCK6

2.13e-03111192PF06920
DomainDOCK

DOCK8 DOCK6

2.13e-03111192IPR026791
DomainDOCK_C

DOCK8 DOCK6

2.13e-03111192IPR010703
DomainDOCK-C2

DOCK8 DOCK6

2.13e-03111192PF14429
DomainDHR-2

DOCK8 DOCK6

2.13e-03111192IPR027357
DomainSugar/inositol_transpt

SLC2A4 SLC2A6

3.48e-03141192IPR003663
DomainOlfact_rcpt

OR4N2 OR4N4 OR5L1 OR2L13 OR1L3 OR1Q1 OR5L2 OR7A10

3.69e-033931198IPR000725
DomainSUGAR_TRANSPORT_2

SLC2A4 SLC2A6

5.14e-03171192PS00217
Domain7TM_GPCR_Srsx

SSTR2 OR1L3 EDNRB ADRA1B

5.74e-031121194SM01381
DomainTerpenoid_cyclase/PrenylTrfase

TCN2 A2ML1

5.76e-03181192IPR008930
PathwayKEGG_MEDICUS_REFERENCE_CA2_CAM_VGCC_RYR_SIGNALING_PATHWAY

RYR1 RYR2 RYR3

4.41e-0511933M47958
PathwayWP_CELLTYPE_DEPENDENT_SELECTIVITY_OF_CCK2R_SIGNALING

RYR1 RYR2 RYR3

7.58e-0513933M39589
Pubmed

Type 1 and type 3 ryanodine receptors are selectively involved in muscarinic antinociception in mice: an antisense study.

RYR1 RYR2 RYR3

4.53e-083125318403125
Pubmed

Heterogeneous gene expression and functional activity of ryanodine receptors in resistance and conduit pulmonary as well as mesenteric artery smooth muscle cells.

RYR1 RYR2 RYR3

4.53e-083125318434746
Pubmed

SPRY domains in ryanodine receptors (Ca(2+)-release channels).

RYR1 RYR2 RYR3

4.53e-08312539204703
Pubmed

The ryanodine receptor/calcium channel genes are widely and differentially expressed in murine brain and peripheral tissues.

RYR1 RYR2 RYR3

4.53e-08312537876312
Pubmed

Ryanodine receptors are expressed in epidermal keratinocytes and associated with keratinocyte differentiation and epidermal permeability barrier homeostasis.

RYR1 RYR2 RYR3

4.53e-083125321881589
Pubmed

Isoform-dependent formation of heteromeric Ca2+ release channels (ryanodine receptors).

RYR1 RYR2 RYR3

4.53e-083125312213830
Pubmed

Expression of the ryanodine receptor type 3 calcium release channel during development and differentiation of mammalian skeletal muscle cells.

RYR1 RYR2 RYR3

4.53e-08312539242641
Pubmed

Bidirectional coupling between ryanodine receptors and Ca2+ release-activated Ca2+ (CRAC) channel machinery sustains store-operated Ca2+ entry in human T lymphocytes.

RYR1 RYR2 RYR3

4.53e-083125322948152
Pubmed

Developmental changes in expression of the three ryanodine receptor mRNAs in the mouse brain.

RYR1 RYR2 RYR3

4.53e-083125310788707
Pubmed

Calcineurin upregulates local Ca(2+) signaling through ryanodine receptor-1 in airway smooth muscle cells.

RYR1 RYR2 RYR3

4.53e-083125325239916
Pubmed

Ca(2+)-induced Ca2+ release in myocytes from dyspedic mice lacking the type-1 ryanodine receptor.

RYR1 RYR2 RYR3

4.53e-08312537621815
Pubmed

A gene-specific cerebral types 1, 2, and 3 RyR protein knockdown induces an antidepressant-like effect in mice.

RYR1 RYR2 RYR3

4.53e-083125318643873
Pubmed

Identification of mutations in the cardiac ryanodine receptor gene in families affected with arrhythmogenic right ventricular cardiomyopathy type 2 (ARVD2).

RYR1 RYR2 RYR3

4.53e-083125311159936
Pubmed

Molecular identification of the ryanodine receptor pore-forming segment.

RYR1 RYR2 RYR3

4.53e-083125310473538
Pubmed

Chromosomal localization of murine ryanodine receptor genes RYR1, RYR2, and RYR3 by in situ hybridization.

RYR1 RYR2 RYR3

4.53e-08312537959768
Pubmed

The organization of proteins in the human red blood cell membrane. A review.

RYR1 RYR2 RYR3

4.53e-08312534600883
Pubmed

Regulation of mouse egg activation: presence of ryanodine receptors and effects of microinjected ryanodine and cyclic ADP ribose on uninseminated and inseminated eggs.

RYR1 RYR2 RYR3

4.53e-08312537635066
Pubmed

A glutathione deficit alters dopamine modulation of L-type calcium channels via D2 and ryanodine receptors in neurons.

RYR1 RYR2 RYR3

1.81e-074125318206662
Pubmed

Ryanodine receptor calcium release channels: lessons from structure-function studies.

RYR1 RYR2 RYR3

1.81e-074125323413940
Pubmed

Requirement for the ryanodine receptor type 3 for efficient contraction in neonatal skeletal muscles.

RYR1 RYR2 RYR3

1.81e-07412539384575
Pubmed

Partial cloning and differential expression of ryanodine receptor/calcium-release channel genes in human tissues including the hippocampus and cerebellum.

RYR1 RYR2 RYR3

1.81e-07412539607712
Pubmed

Conserved and divergent functions of Nfix in skeletal muscle development during vertebrate evolution.

RYR1 RYR2 RYR3

1.81e-074125323482488
Pubmed

Presenilins regulate calcium homeostasis and presynaptic function via ryanodine receptors in hippocampal neurons.

RYR1 RYR2 RYR3

4.51e-075125323918386
Pubmed

Kv2.1 mediates spatial and functional coupling of L-type calcium channels and ryanodine receptors in mammalian neurons.

KCNB2 RYR2 KCNB1

4.51e-075125331663850
Pubmed

Protein kinase C-epsilon regulates local calcium signaling in airway smooth muscle cells.

RYR1 RYR2 RYR3

4.51e-075125319011160
Pubmed

Membrane depolarization causes a direct activation of G protein-coupled receptors leading to local Ca2+ release in smooth muscle.

RYR1 RYR2 RYR3

8.99e-076125319549818
Pubmed

Rectification of muscle and nerve deficits in paralyzed ryanodine receptor type 1 mutant embryos.

RYR1 RYR2 RYR3

8.99e-076125326025922
Pubmed

Roles of I(f) and intracellular Ca2+ release in spontaneous activity of ventricular cardiomyocytes during murine embryonic development.

RYR1 RYR2 RYR3

8.99e-076125323463619
Pubmed

FKBP12.6 and cADPR regulation of Ca2+ release in smooth muscle cells.

RYR1 RYR2 RYR3

8.99e-076125314592808
Pubmed

A calcium-induced calcium release mechanism supports luteinizing hormone-induced testosterone secretion in mouse Leydig cells.

RYR1 RYR2 RYR3

8.99e-076125320519450
Pubmed

Essential Roles of Intracellular Calcium Release Channels in Muscle, Brain, Metabolism, and Aging.

RYR1 RYR2 RYR3

8.99e-076125325966694
Pubmed

HIV-1 Tat activates neuronal ryanodine receptors with rapid induction of the unfolded protein response and mitochondrial hyperpolarization.

RYR1 RYR2 RYR3

8.99e-076125319009018
Pubmed

IP3Rs are sufficient for dendritic cell Ca2+ signaling in the absence of RyR1.

RYR1 RYR2 RYR3

8.99e-076125316844763
Pubmed

Developmental expression of the calcium release channels during early neurogenesis of the mouse cerebral cortex.

RYR1 RYR2 RYR3

1.57e-067125311860456
Pubmed

Human immunodeficiency virus-1 Tat activates calpain proteases via the ryanodine receptor to enhance surface dopamine transporter levels and increase transporter-specific uptake and Vmax.

RYR1 RYR2 RYR3

1.57e-067125320962236
Pubmed

Roles of IP3R and RyR Ca2+ channels in endoplasmic reticulum stress and beta-cell death.

RYR1 RYR2 RYR3

2.50e-068125319033399
Pubmed

Sequential docking, molecular differentiation, and positioning of T-Tubule/SR junctions in developing mouse skeletal muscle.

RYR1 RYR2 RYR3

2.50e-068125311784029
Pubmed

LMO7 deficiency reveals the significance of the cuticular plate for hearing function.

TMC1 TMC2 LMO7

2.50e-068125330850599
Pubmed

Differences in gene expression between mouse and human for dynamically regulated genes in early embryo.

PRAMEF33 PRAMEF10 NLRP7 NLRP2

3.05e-0628125425089626
Pubmed

Thirteen Ovary-Enriched Genes Are Individually Not Essential for Female Fertility in Mice.

PRAMEF33 PRAMEF10 NLRP7 NLRP2

4.05e-0630125438786026
Pubmed

AAV-mediated intramuscular delivery of myotubularin corrects the myotubular myopathy phenotype in targeted murine muscle and suggests a function in plasma membrane homeostasis.

LAMA2 RYR1 RYR2

5.34e-0610125318434328
Pubmed

New molecular components supporting ryanodine receptor-mediated Ca(2+) release: roles of junctophilin and TRIC channel in embryonic cardiomyocytes.

RYR1 RYR2 RYR3

9.74e-0612125319095005
Pubmed

Kv2.1 Clustering Contributes to Insulin Exocytosis and Rescues Human β-Cell Dysfunction.

KCNB2 KCNB1

1.28e-052125228607108
Pubmed

NLRP2 controls age-associated maternal fertility.

NLRP7 NLRP2

1.28e-052125227881734
Pubmed

NLRP2 is highly expressed in a mouse model of ischemic stroke.

NLRP7 NLRP2

1.28e-052125227693696
Pubmed

Variable number of TMC1-dependent mechanotransducer channels underlie tonotopic conductance gradients in the cochlea.

TMC1 TMC2

1.28e-052125229872055
Pubmed

Tmc1 Point Mutation Affects Ca2+ Sensitivity and Block by Dihydrostreptomycin of the Mechanoelectrical Transducer Current of Mouse Outer Hair Cells.

TMC1 TMC2

1.28e-052125226758827
Pubmed

The contribution of TMC1 to adaptation of mechanoelectrical transduction channels in cochlear outer hair cells.

TMC1 TMC2

1.28e-052125231633194
Pubmed

Altered ryanodine receptor expression in mild cognitive impairment and Alzheimer's disease.

RYR2 RYR3

1.28e-052125221531043
Pubmed

Modulation of calcium signalling by dominant negative splice variant of ryanodine receptor subtype 3 in native smooth muscle cells.

RYR2 RYR3

1.28e-052125216678258
Pubmed

Reproductive Outcomes from Maternal Loss of Nlrp2 Are Not Improved by IVF or Embryo Transfer Consistent with Oocyte-Specific Defect.

NLRP7 NLRP2

1.28e-052125233090377
Pubmed

Cell type-specific spatial and functional coupling between mammalian brain Kv2.1 K+ channels and ryanodine receptors.

RYR1 KCNB1

1.28e-052125224962901
Pubmed

Kv2 Ion Channels Determine the Expression and Localization of the Associated AMIGO-1 Cell Adhesion Molecule in Adult Brain Neurons.

KCNB2 KCNB1

1.28e-052125229403353
Pubmed

TMC1 and TMC2 are components of the mechanotransduction channel in hair cells of the mammalian inner ear.

TMC1 TMC2

1.28e-052125223871232
Pubmed

Principal mutation hotspot for central core disease and related myopathies in the C-terminal transmembrane region of the RYR1 gene.

RYR1 RYR3

1.28e-052125212565913
Pubmed

Are TMCs the Mechanotransduction Channels of Vertebrate Hair Cells?

TMC1 TMC2

1.28e-052125227798174
Pubmed

Contractile impairment and structural alterations of skeletal muscles from knockout mice lacking type 1 and type 3 ryanodine receptors.

RYR1 RYR3

1.28e-05212529489997
Pubmed

A genetic association study of NLRP2 and NLRP7 genes in idiopathic recurrent miscarriage.

NLRP7 NLRP2

1.28e-052125223360675
Pubmed

Skeletal and cardiac ryanodine receptors exhibit different responses to Ca2+ overload and luminal ca2+.

RYR1 RYR2

1.28e-052125217259277
Pubmed

Functional and morphological features of skeletal muscle from mutant mice lacking both type 1 and type 3 ryanodine receptors.

RYR1 RYR3

1.28e-05212529192302
Pubmed

The block of ryanodine receptors selectively inhibits fetal myoblast differentiation.

RYR1 RYR3

1.28e-052125212640042
Pubmed

The effects of Tmc1 Beethoven mutation on mechanotransducer channel function in cochlear hair cells.

TMC1 TMC2

1.28e-052125226324676
Pubmed

Early peripheral activity alters nascent subplate circuits in the auditory cortex.

TMC1 TMC2

1.28e-052125233579707
Pubmed

A quantitative trait locus for SBP maps near KCNB1 and PTGIS in a population isolate.

PTGIS KCNB1

1.28e-052125219265782
Pubmed

Ryanodine receptor oligomeric interaction: identification of a putative binding region.

RYR1 RYR2

1.28e-052125214722100
Pubmed

Structural and functional interactions within ryanodine receptor.

RYR1 RYR2

1.28e-052125226009179
Pubmed

The role of transmembrane channel-like proteins in the operation of hair cell mechanotransducer channels.

TMC1 TMC2

1.28e-052125224127526
Pubmed

Isolation and partial cloning of ryanodine-sensitive Ca2+ release channel protein isoforms from human myometrial smooth muscle.

RYR1 RYR3

1.28e-05212527556644
Pubmed

Dominant and recessive deafness caused by mutations of a novel gene, TMC1, required for cochlear hair-cell function.

TMC1 TMC2

1.28e-052125211850618
Pubmed

Structure and Function of the Human Ryanodine Receptors and Their Association with Myopathies-Present State, Challenges, and Perspectives.

RYR1 RYR2

1.28e-052125232899693
Pubmed

Possible involvement of ryanodine receptor-mediated intracellular calcium release in the effect of corticotropin-releasing factor on adrenocorticotropin secretion.

RYR1 RYR3

1.28e-052125214592949
Pubmed

Treatment of autosomal dominant hearing loss by in vivo delivery of genome editing agents.

TMC1 TMC2

1.28e-052125229258297
Pubmed

Tissue-specific alternative splicing of mouse brain type ryanodine receptor/calcium release channel mRNA.

RYR2 RYR3

1.28e-05212528898078
Pubmed

Remodeling neuronal ER-PM junctions is a conserved nonconducting function of Kv2 plasma membrane ion channels.

KCNB2 KCNB1

1.28e-052125230091655
Pubmed

The speed of the hair cell mechanotransducer channel revealed by fluctuation analysis.

TMC1 TMC2

1.28e-052125234411238
Pubmed

Ryanodine receptors in muscarinic receptor-mediated bronchoconstriction.

RYR1 RYR3

1.28e-052125215894801
Pubmed

Recent advances in understanding the ryanodine receptor calcium release channels and their role in calcium signalling.

RYR1 RYR2

1.28e-052125230542613
Pubmed

Mechanical gating of the auditory transduction channel TMC1 involves the fourth and sixth transmembrane helices.

TMC1 TMC2

1.28e-052125235857511
Pubmed

A Tmc1 mutation reduces calcium permeability and expression of mechanoelectrical transduction channels in cochlear hair cells.

TMC1 TMC2

1.28e-052125231548403
Pubmed

The mouse sino-atrial node expresses both the type 2 and type 3 Ca(2+) release channels/ryanodine receptors.

RYR2 RYR3

1.28e-052125214550562
Pubmed

TMC1 Forms the Pore of Mechanosensory Transduction Channels in Vertebrate Inner Ear Hair Cells.

TMC1 TMC2

1.28e-052125230138589
Pubmed

Ryanodine receptors are expressed and functionally active in mouse spermatogenic cells and their inhibition interferes with spermatogonial differentiation.

RYR1 RYR2

1.28e-052125215280431
Pubmed

Expression of the ryanodine receptor isoforms in immune cells.

RYR1 RYR2

1.28e-052125211673493
Pubmed

New Tmc1 Deafness Mutations Impact Mechanotransduction in Auditory Hair Cells.

TMC1 TMC2

1.28e-052125233824189
Pubmed

Nlrp2, a maternal effect gene required for early embryonic development in the mouse.

NLRP7 NLRP2

1.28e-052125222295082
Pubmed

B-lymphocytes from malignant hyperthermia-susceptible patients have an increased sensitivity to skeletal muscle ryanodine receptor activators.

RYR1 RYR2

1.28e-052125211673462
Pubmed

Morphological abnormalities of adrenal gland and hypertrophy of liver in mutant mice lacking ryanodine receptors.

RYR1 RYR3

1.28e-05212529799464
Pubmed

Effect of calmodulin on Ca2+-induced Ca2+ release of skeletal muscle from mutant mice expressing either ryanodine receptor type 1 or type 3.

RYR1 RYR3

1.28e-05212529817784
Pubmed

Distinct Cell- and Layer-Specific Expression Patterns and Independent Regulation of Kv2 Channel Subtypes in Cortical Pyramidal Neurons.

KCNB2 KCNB1

1.28e-052125226538660
Pubmed

Suppressing NLRP2 expression accelerates hepatic steatosis: A mechanism involving inflammation and oxidative stress.

NLRP7 NLRP2

1.28e-052125230454891
Pubmed

Crystal structures of wild type and disease mutant forms of the ryanodine receptor SPRY2 domain.

RYR1 RYR2

1.28e-052125225370123
Pubmed

Developmental changes in the cochlear hair cell mechanotransducer channel and their regulation by transmembrane channel-like proteins.

TMC1 TMC2

1.28e-052125223277480
Pubmed

NLRP2 inflammasome in dorsal root ganglion as a novel molecular platform that produces inflammatory pain hypersensitivity.

NLRP7 NLRP2

1.28e-052125231162334
Pubmed

Tmc gene therapy restores auditory function in deaf mice.

TMC1 TMC2

1.28e-052125226157030
Pubmed

RNA Interference Prevents Autosomal-Dominant Hearing Loss.

TMC1 TMC2

1.28e-052125227236922
Pubmed

Decreased expression of ryanodine receptors alters calcium-induced calcium release mechanism in mdx duodenal myocytes.

RYR2 RYR3

1.28e-052125214985349
Pubmed

Ryanodine receptors in human pancreatic beta cells: localization and effects on insulin secretion.

RYR1 RYR2

1.28e-052125215033925
Pubmed

Development and localization of reverse-polarity mechanotransducer channels in cochlear hair cells.

TMC1 TMC2

1.28e-052125227162344
Pubmed

Thermodynamics of calmodulin binding to cardiac and skeletal muscle ryanodine receptor ion channels.

RYR1 RYR2

1.28e-052125218618700
Pubmed

TMC1 and TMC2 Localize at the Site of Mechanotransduction in Mammalian Inner Ear Hair Cell Stereocilia.

TMC1 TMC2

1.28e-052125226321635
GeneFamilyRyanodine receptors|Protein phosphatase 1 regulatory subunits

RYR1 RYR2 RYR3

1.08e-073873287
GeneFamilyTransmembrane channel likes

TMC1 TMC2

6.29e-0488721135
GeneFamilyUPF1 like RNA helicases

MOV10L1 AQR

1.22e-03118721169
ToppCellBAL-Control-Myeloid-Macrophage|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

FNIP2 PSAP TCN2 ADAMTS5 EDNRB MERTK PLTP

7.41e-0718312278e9d45c96b44558158e3d59613f64a73d5390c19
ToppCellBAL-Control-Myeloid-Macrophage-transitional_Macro-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

FNIP2 PSAP TCN2 ADAMTS5 EDNRB MERTK PLTP

7.41e-0718312270408d991ddb639594b45d5cb2432dd29289167b1
ToppCellBAL-Control-Myeloid-Macrophage-transitional_Macro|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

FNIP2 PSAP TCN2 ADAMTS5 EDNRB MERTK PLTP

7.41e-07183122779f05b8a967124d831b0baef137e30659f5917a7
ToppCellBAL-Control-Myeloid-Macrophage-transitional_Macro-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

FNIP2 PSAP TCN2 ADAMTS5 EDNRB MERTK PLTP

7.69e-07184122792202e1cd0bba1ce4b061ebcb8a2af5bb590542a
ToppCellBAL-Control-Myeloid-Macrophage|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

FNIP2 PSAP TCN2 ADAMTS5 EDNRB MERTK PLTP

7.69e-0718412277331535d469453a5264dcb0270a97f63d3b55201
ToppCellBAL-Control-Myeloid-Macrophage-transitional_Macro|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

FNIP2 PSAP TCN2 ADAMTS5 EDNRB MERTK PLTP

7.69e-071841227337e38a6b2b6770cc992d88b006829f194841b10
ToppCellcritical-Myeloid-Non-resident_Macrophage|critical / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

FNIP2 PSAP FLVCR2 NRROS CYFIP1 SLC2A6 MERTK

1.30e-061991227193325768b17d3123ae855317f381a01088b5dac
ToppCellsevere_COVID-19-pDC|severe_COVID-19 / disease group, cell group and cell class (v2)

NLRP7 NLRP2 RYR1 KCNB1 MMP15 RAPGEFL1

5.11e-061591226ea5088d27e42b8850455764d53b757ea8d8f14bc
ToppCell3'_v3-lymph-node_spleen-Myeloid_Mac-Intestinal_macrophages|lymph-node_spleen / Manually curated celltypes from each tissue

TCN2 STIMATE SLC19A2 CYFIP1 MERTK PLTP

9.43e-06177122652c2ba74a8605260a2623e7d151286e504ac4d19
ToppCellfacs-Marrow-T-cells-3m-Hematologic-Unknown_Progenitor|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PARP11 RYR1 PLEKHH3 ARFGEF3 SLC7A3 GLB1

1.14e-051831226b0b835f3b1de1bd46a47e1b805aa8994cd3a4e3e
ToppCellControl-Myeloid-transitional_Macro|Control / Disease group,lineage and cell class （2021.01.30）

FNIP2 PSAP TCN2 EDNRB MERTK PLTP

1.45e-0519112263ed0b1ff628a165e3c92c2e493206015f57dccfe
ToppCellChildren_(3_yrs)-Immune-alveolar_macrophage_(MARCO_positive)-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

FNIP2 GPD2 PSAP CYFIP1 MERTK DOP1B

1.63e-0519512269d649ac7d2af313481069c95349efc0c68449e2b
ToppCellBAL-Mild-Myeloid-MoAM-MoAM1|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)

FNIP2 PSAP NRROS SSTR2 EDNRB MERTK

1.68e-0519612267c8aa5853d7096628e35af665097c0299c329753
ToppCellBAL-Mild-Myeloid-MoAM-MoAM1-|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

FNIP2 PSAP NRROS SSTR2 EDNRB MERTK

1.68e-051961226f60b220ed117bcc33e0f7bbf5b53d3b1422ebaca
ToppCellBAL-Mild-Myeloid-MoAM-MoAM1-|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

FNIP2 PSAP NRROS SSTR2 EDNRB MERTK

1.68e-051961226bcd274db4955ea76ca26267a272c7d1929db24f4
ToppCellBAL-Mild-Myeloid-MoAM-MoAM1|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

FNIP2 PSAP NRROS SSTR2 EDNRB MERTK

1.68e-05196122680b9139d91dda4de69830d2d443859e047ab5503
ToppCellMild_COVID-19-Myeloid-MoAM1|Mild_COVID-19 / Disease group,lineage and cell class （2021.01.30）

FNIP2 PSAP NRROS SSTR2 EDNRB MERTK

1.68e-051961226ea3fbe81b4ecb6ccc8031f6d99da93c9f9f8c1aa
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Immune-Myeloid|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

PSAP DOCK8 RYR1 MERTK FMNL1 PLTP

1.73e-0519712268af4a1e35ce9fb4ea3d26ab619599efb7eac43a5
ToppCellNS-critical-LOC-Myeloid-Macrophage|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

TCN2 FLVCR2 CYFIP1 SLC2A6 MERTK PLTP

1.73e-0519712265fb0696376a5501b7c87e0f2f5e4fff3da2903f2
ToppCellBAL-Mild-Myeloid-MoAM|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

FNIP2 PSAP NRROS SSTR2 EDNRB MERTK

1.73e-0519712260f40dd3530eb8d02e79b32f942efe3b65b8f6ee6
ToppCellBAL-Mild-Myeloid-MoAM|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)

FNIP2 PSAP NRROS SSTR2 EDNRB MERTK

1.73e-051971226a6aa5991d566c28440f7e24a30933e69669064f2
ToppCell10x_3'_v3-lymph_node_(10x_3'_v3)-myeloid-myeloid_macrophage|lymph_node_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

FNIP2 PSAP TCN2 CYFIP1 MERTK PLTP

1.78e-051981226c08018f099a381a66993cb60288954a6e47f105f
ToppCell10x_3'_v3-lymph_node_(10x_3'_v3)-myeloid-myeloid_macrophage-macrophage|lymph_node_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

FNIP2 PSAP TCN2 CYFIP1 MERTK PLTP

1.78e-05198122627cc7f786fb8cb230589d762a4e51b46265c1f19
ToppCell10x_3'_v3-spleen_(10x_3'_v3)-myeloid-myeloid_macrophage|spleen_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

FNIP2 PSAP FLVCR2 CYFIP1 MERTK PLTP

1.78e-0519812269aaff68107ae4542f904b142d23669f2fcd557ac
ToppCell10x_3'_v3-spleen_(10x_3'_v3)-myeloid-myeloid_macrophage-macrophage|spleen_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

FNIP2 PSAP FLVCR2 CYFIP1 MERTK PLTP

1.78e-0519812265aaf3861c53763cf09bb628c9d2eabb6a7277021
ToppCellwk_15-18-Hematologic-Myeloid-SPP1+_Mac|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

PSAP NRROS RYR1 CYFIP1 MERTK PLTP

1.83e-051991226c7fc2ac1601346aac71e7620a8a440fde8d92dbd
ToppCellprimary_visual_cortex-Non-neuronal-astrocyte|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

TCN2 LAMA2 EDNRB MERTK SLC38A3

6.41e-05153122595b28c5bd10ffb74c0993ebd565038b9818e4bd2
ToppCellprimary_visual_cortex-Non-neuronal-astrocyte-Astro|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

TCN2 LAMA2 EDNRB MERTK SLC38A3

6.41e-051531225b09f8def40a1ea56722f3398f61a036667b61cd9
ToppCellprimary_visual_cortex-Non-neuronal-astrocyte-Astro-Astro_Aqp4|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

TCN2 LAMA2 EDNRB MERTK SLC38A3

6.41e-0515312253ab9d55b3db51715c1d61eca142384195ce4b54f
ToppCellCV-Healthy-3|Healthy / Virus stimulation, Condition and Cluster

SPPL3 ZNF19 PAXBP1 KLHL21 CDK6

6.61e-05154122526bf81a86700db7e65c2384ffe94ed4253ea4047
ToppCellfacs-Marrow-B-cells-24m-Lymphocytic-precursor_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ABCA12 LAMA2 RYR2 RYR3 MOV10L1

7.92e-051601225c381ec6be8cf887861cc18f831a20db42f953fe1
ToppCellfacs-Marrow-B-cells-24m-Lymphocytic-pre_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ABCA12 LAMA2 RYR2 RYR3 MOV10L1

7.92e-05160122525c8f3d2a6d14ff0ca0b965fce89d3ff22f40585
ToppCellAdult-Mesenchymal-airway_smooth_muscle_cell-D122|Adult / Lineage, Cell type, age group and donor

ZIM2 PTGIS RYR2 RYR3 A2ML1

8.16e-05161122564891f6f2ee1693c8481e951b9346e2f92d602e3
ToppCellCV-Healthy-3|CV / Virus stimulation, Condition and Cluster

SPPL3 SNX33 ZNF19 PAXBP1 KLHL21

8.16e-051611225fd4a79385ea967b9900dc76a3add813b894a3a28
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-Degenerative_Endothelial_Cell-Degenerative_Peritubular_Capilary_Endothelial_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ADGRB3 TMEM187 TIE1 MOV10L1 DOCK6

8.64e-05163122573c03e29a6d7a6863c5e9aa5e8b963ef691f1ddb
ToppCellPBMC_fresh-frozen-Mild-Moderate_progression_d12-25-Myeloid-Monocytic-Nonclassical_Monocyte-Mono_c4-CD14-CD16|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)

TCN2 SLC19A2 RYR1 CLDN19 MERTK

1.02e-041691225e3100eb587005e160bd0b7990fa57ec49765133d
ToppCellfacs-Lung-nan-3m-Endothelial-Vein_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FLVCR2 RALGAPA2 CYFIP1 KCNB1 TIE1

1.05e-0417012258e1f757ed62218c0fb6525f49d142dd2cd29acf9
ToppCellPND07-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-ASMC-ASMC_mature|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

PTGIS SLC2A4 EDNRB RYR2 MOV10L1

1.05e-041701225cb1ed6bd409ee1cf11be0d5e7cdcffe2ab220d38
ToppCellfacs-Lung-nan-3m-Endothelial-vein_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FLVCR2 RALGAPA2 CYFIP1 KCNB1 TIE1

1.05e-04170122567d7e1da3ebd2d14cb2e67799e94d655027ed5c4
ToppCellPND07-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-ASMC|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

PTGIS SLC2A4 EDNRB RYR2 MOV10L1

1.05e-041701225da4fb1e186e9bec6bba0b25f2a0e68f9e11c6017
ToppCellPND10-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-ASMC|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ADAMTS5 PTGIS SLC2A4 EDNRB RYR3

1.08e-04171122582de2885c8ce4fb7776da6a0207b3355c0910121
ToppCellPND10-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-ASMC-ASMC_mature|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ADAMTS5 PTGIS SLC2A4 EDNRB RYR3

1.08e-04171122509e653973962fb884878089d281f0947f7a285f6
ToppCellkidney_cells-Hypertensive_with+without-CKD-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell-mesangial_typical-aged|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

DOCK8 LAMA2 ADAMTS5 KCNB1 LMO7

1.21e-0417512251b4cefae400bf756d09ece32d3f5c0bd4c6ad73f
ToppCellfacs-Brain_Non-Myeloid-Cerebellum_-18m-Macroglial-Oligodendrocyte_progenitor_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MAGEE2 PLPPR5 EDNRB SLC7A3 MMP15

1.24e-041761225ef0ff02897104e938c8a632357d8f1a6f014e68a
ToppCellfacs-Brain_Non-Myeloid-Cerebellum_-18m-Macroglial-oligodendrocyte_precursor_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MAGEE2 PLPPR5 EDNRB SLC7A3 MMP15

1.24e-041761225da0983929fa682a68e536c298a2d7add188b7563
ToppCellprimary_visual_cortex-Non-neuronal|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

TCN2 LAMA2 EDNRB MERTK SLC38A3

1.24e-0417612252c92f3f55d668cfe80051b5128160a6dc3aec4e8
ToppCell3'-Adult-SmallIntestine-Hematopoietic-B_cells-Memory_B|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

DOCK8 ESPNL NRROS FMNL1 SP140

1.27e-0417712250d1c39e99144fdb9c7f6f98a1ade41c73db45b65
ToppCellFetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)-D150|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

FNIP2 ARFGEF3 ADRA1B LMO7 LRBA

1.34e-041791225815b959ce8721c5ded70c0ca6e318dafc691746e
ToppCell367C-Endothelial_cells-Endothelial-C_(Capillary_Aerocyte_)|367C / Donor, Lineage, Cell class and subclass (all cells)

TCN2 EDNRB FRY TIE1 DOCK6

1.38e-041801225162cec1734e560c068cd61717e40e18dcf92308c
ToppCelldroplet-Lung-nan-18m-Mesenchymal-Pericyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LAMA2 RYR2 PLEKHH3 SEMA4C ADRA1B

1.38e-041801225f6a05b3751b01e74b2de8440801b0eb2e723c199
ToppCell367C-Endothelial_cells-Endothelial-C_(Capillary_Aerocyte_)-|367C / Donor, Lineage, Cell class and subclass (all cells)

TCN2 EDNRB FRY TIE1 DOCK6

1.38e-04180122533c86c22ba877358cd8c1e39b5c0b3dc3a45b7dd
ToppCelldroplet-Lung-nan-18m-Mesenchymal-pericyte_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LAMA2 RYR2 PLEKHH3 SEMA4C ADRA1B

1.38e-041801225dfc75ae4395ff46fbec2c54915d98ead5a1ba1a1
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ABCA12 RYR2 RYR3 ARFGEF3 MYO16

1.53e-0418412252cbed6462fea2622871bb7e49b0df3d984239281
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ABCA12 RYR2 RYR3 ARFGEF3 MYO16

1.53e-041841225ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ABCA12 RYR2 RYR3 ARFGEF3 MYO16

1.53e-0418412252b19a8c5f823e00812908b23e66bb4e563278aff
ToppCelldroplet-Kidney-nan-21m-Mesenchymal-fibroblast|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LAMA2 ADAMTS5 PTGIS BNC1 ADRA1B

1.53e-0418412253bffadb0cb2e0d825bdb6cfc5d23f5436cbc3efd
ToppCellCV-Moderate-7|Moderate / Virus stimulation, Condition and Cluster

DOCK8 DENND4B LRBA DOP1B CDK6

1.56e-041851225a6c9203ce6c2892a4a369c9bcfb85720f01cbb3f
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal-Glutamatergic_Excit|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

FSTL4 KCNB2 RYR2 LMO7 VPS13A

1.60e-04186122584ba666237c18189d7e7556bd92dd953af733c00
ToppCell5'-Adult-Appendix-Mesenchymal-fibroblastic-mLN_Stroma_(FMO2+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SLC19A2 LAMA2 PTGIS EDNRB PLTP

1.60e-0418612257582b5154d8e5a4434817b5ab77a10b789ea2288
ToppCellEpithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)|World / Lineage, Cell type, age group and donor

FNIP2 ARFGEF3 ADRA1B LMO7 LRBA

1.64e-04187122581cc8435b2704a9a8287b3f54acaae0f11dd4ac7
ToppCellE17.5-Endothelial-unknown_endothelial_cell|E17.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

NRROS FRY TIE1 SLC38A3 PLTP

1.64e-041871225da885c26ccc5189b1ff1f607552e00a5c0e49e7e
ToppCellE17.5-Endothelial-unknown_endothelial_cell-endothelial_unknown_1|E17.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

NRROS FRY TIE1 SLC38A3 PLTP

1.64e-0418712251f358d02ec69d44dea2e2831af9473ed05dcf8cc
ToppCellCOVID-19-lung-Artery_EC|lung / Disease (COVID-19 only), tissue and cell type

EXOC6 RALGAPA2 PTGIS TIE1 DOCK6

1.69e-041881225eecd7482b3c97d7f49993cb17edfab30c61232fc
ToppCellfacs-Pancreas-Endocrine-24m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PSAP ARFGEF3 SATB1 KCNB1 DISP2

1.69e-041881225a91443aa8fa8fa87f7501c59219daa0305bd0bbf
ToppCellCOVID-19-lung-Artery_EC|COVID-19 / Disease (COVID-19 only), tissue and cell type

EXOC6 RALGAPA2 PTGIS TIE1 DOCK6

1.77e-04190122507b675befcd1d0a9c90cb17b5d22323468325d51
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Immune-Myeloid-Macrophage_Dendritic|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

DOCK8 RYR1 MERTK FMNL1 PLTP

1.81e-04191122551f5af610983aa73b9f4ece6f27d281ebff89a04
ToppCellfacs-Heart-LA-3m-Endothelial-endothelial_cell_of_coronary_artery|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EDNRB FRY TIE1 LMO7 MMP15

1.81e-041911225a15f0fb4bd7dd77ef5f931b6fc9d68697deec1d1
ToppCellfacs-Heart-LV-24m-Mesenchymal-ventricular_cardiomyocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RTN4R RYR2 ADRA1B MOV10L1 SLC38A3

1.81e-041911225543da1197c7e62f2c9cbd4a51414bbaaa6d1a92f
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Immune-Myeloid-Macrophage_Dendritic-M2_Macrophage|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

DOCK8 RYR1 MERTK FMNL1 PLTP

1.81e-0419112258fd6bdc9d2b1c8d364221d7bc68d03921b668ab5
ToppCellfacs-Heart-LV-24m-Mesenchymal-ventricular_myocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RTN4R RYR2 ADRA1B MOV10L1 SLC38A3

1.81e-0419112259d7d680da3979e256191b534ebd14c5383e0cf93
ToppCellFetal_29-31_weeks-Immune-interstitial_macrophage_(C1Q_positive)-D062|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

PSAP DOCK8 RYR1 MERTK PLTP

1.81e-04191122524d75b7e1d6fb9d24aa7844f584ee888a449841f
ToppCellfacs-Heart-LA-3m-Endothelial-coronary_vascular_endothelial_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EDNRB FRY TIE1 LMO7 MMP15

1.81e-041911225827be47d3574c6c5b021c6f1c1670834344f10cb
ToppCell5'-Adult-LymphNode-Mesenchymal|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TMC2 SLC19A2 LAMA2 EDNRB PLTP

1.81e-041911225054e9a79bd1486fd812bc7418fb091664fe3a646
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ADGRB3 LAMA2 ADAMTS5 EDNRB FRY

1.81e-0419112257b0d42a877540dbb346a76a62403e0d5d3e07fa6
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ADGRB3 LAMA2 ADAMTS5 EDNRB FRY

1.81e-041911225cd854b9c426924fdc84bf7f411f6dea447143e79
ToppCell5'-Adult-LymphNode-Mesenchymal-fibroblastic-mLN_Stroma_(FMO2+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TMC2 SLC19A2 LAMA2 EDNRB PLTP

1.86e-0419212259479e9859140ba98abfe88414de0b28fc2bf43b7
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Immune-Myeloid-Macrophage_Dendritic|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

DOCK8 RYR1 MERTK FMNL1 PLTP

1.86e-04192122586d792682ba51696f503c79625dd20f87bcf651f
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Immune-Myeloid-Macrophage_Dendritic-M2_Macrophage|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

DOCK8 RYR1 MERTK FMNL1 PLTP

1.86e-041921225d0ad6a205ad50a3c523fa68676996b289eabc5de
ToppCell5'-Adult-LymphNode-Mesenchymal-fibroblastic|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TMC2 SLC19A2 LAMA2 EDNRB PLTP

1.86e-041921225d7faa993f68e530ad55185505384ae155d36c222
ToppCellControl-Myeloid-Monocyte-derived_macrophages|Control / group, cell type (main and fine annotations)

PSAP DOCK8 RYR1 MERTK PLTP

1.90e-041931225a6b3bd01e585e2e3fbe9bf693a2e385773123f8e
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Immune-Myeloid-Macrophage_Dendritic|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

DOCK8 RYR1 MERTK FMNL1 PLTP

1.90e-041931225bd08555f02db8bc903caacae57e80bb91e2556ce
ToppCellLV-01._Fibroblast_I|LV / Chamber and Cluster_Paper

ADGRB3 LAMA2 ADAMTS5 PTGIS EDNRB

1.90e-041931225dc17f3b9758936d428cf17f77a1ce6d4c479b165
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Immune-Myeloid-Macrophage_Dendritic-M2_Macrophage|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

DOCK8 RYR1 MERTK FMNL1 PLTP

1.90e-041931225374d0526a071e973c3f43b4564f78f6933bb67ed
ToppCellCOVID_vent-Myeloid-Monocytic-CD16+_Monocyte|COVID_vent / Disease condition, Lineage, Cell class and subclass

PSAP TCN2 CYFIP1 SLC2A6 MERTK

1.95e-041941225b133d3d198360269cc449a75d34c29be377d91e0
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Descending_Vasa_Recta_Endothelial_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

EXOC6 ADAMTS5 RALGAPA2 RYR2 TIE1

1.95e-041941225a429d22c8c9d0fd3bfa9f877a6364cecad68db30
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Immune-Myeloid-Macrophage_Dendritic-M2_Macrophage|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

PSAP RYR1 MERTK FMNL1 PLTP

1.95e-04194122545708cb2cafde10bf4e4798b81d47c3b1f6aaa14
ToppCellCOVID-19-lung-Macrophage_CD163hi_MERTKhi|lung / Disease (COVID-19 only), tissue and cell type

PSAP DOCK8 FLVCR2 MERTK FMNL1

2.00e-041951225148fff8c3c9ba45ec36e98dff1be57e3f8294506
ToppCellNS-critical-d_07-13-Myeloid-Non-resident_Macrophage|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

FNIP2 PSAP FLVCR2 NRROS SLC2A6

2.00e-041951225ee8743d39996bb756f50db32748e8a902d3294b8
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Immune-Myeloid-Macrophage_Dendritic|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

PSAP RYR1 MERTK FMNL1 PLTP

2.00e-041951225247803cf58c6d9c561a52aa34e581188ddad197e
ToppCelldroplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GPD2 PSAP SATB1 KCNB1 VPS13A

2.00e-0419512253e519cffa6144a62b06124642a14c9ff39b76554
ToppCellFetal_29-31_weeks-Immune-interstitial_macrophage_(C1Q_positive)|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

PSAP DOCK8 RYR1 MERTK PLTP

2.00e-041951225312d9625655b38f1a7c2bf8f8bb7b667ebdf9617
ToppCelldroplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GPD2 PSAP SATB1 KCNB1 VPS13A

2.00e-0419512257796ea9247f4c63762f0de8490fed08b9717fa23
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

EXOC6 ADGRB3 PTGIS RYR3 TIE1

2.00e-04195122577e47d2e8b3eb7f7c9620369ccaf87581f923bdb
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Endothelial|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

EXOC6 ADGRB3 RYR3 TIE1 DOCK6

2.05e-0419612258ad8efb631164b46f0c082572270188e5ead20bf
ToppCell10x5'v1-week_14-16-Myeloid_macrophage|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

PSAP ARFGEF3 CYFIP1 MERTK PLTP

2.05e-041961225e0447ad2efb021b63c7fef000d39b6b21fbe6113
ToppCellMid-temporal_gyrus_(MTG)-Neuronal|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ADGRB3 KCNB2 RYR2 FRY KCNB1

2.05e-041961225676c56b44ac29f7baecb62f49bb8597cc74c0a88
ToppCellCOVID-19-lung-Macrophage_metabolically_active|lung / Disease (COVID-19 only), tissue and cell type

PSAP DOCK8 FLVCR2 MERTK PLTP

2.05e-041961225a753d76d764c181eecb0e17a794a2e7d0ff70136
ToppCell10x5'v1-week_14-16-Myeloid_macrophage-stroma|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

PSAP ARFGEF3 CYFIP1 MERTK PLTP

2.05e-0419612253bca88eede3dd7368715ced02e3bacd1e3e82cab
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

EXOC6 ADGRB3 RYR3 TIE1 DOCK6

2.05e-0419612259606ea7e42f707e69ea891b3521037613b9675f5
ToppCellCOVID-19-lung-Macrophage_metabolically_active|COVID-19 / Disease (COVID-19 only), tissue and cell type

PSAP DOCK8 FLVCR2 MERTK PLTP

2.05e-0419612251b7928f4eee94d4bb6ea410bab68a471dba12979
Druglactosyl lysosphingolipid

PSAP RYR1 RYR3 GLB1

9.37e-0891214CID006439268
Drugcis-diammineplatinum(II

RYR1 RYR2 RYR3

1.46e-0731213CID000159790
Drug2-hydroxyheptanoic acid

RYR1 RYR2 RYR3

1.46e-0731213CID002750949
Drug8N3-cADPR

RYR1 RYR2 RYR3

1.46e-0731213CID000127713
Drugaminodantrolene

RYR1 RYR2 RYR3

1.46e-0731213CID009570289
Drug2-hydroxycarbazole

RYR1 RYR2 RYR3

1.46e-0731213CID000093551
DrugRyanodyl 3-(pyridine-3-carboxylate

RYR1 RYR2 RYR3

1.46e-0731213CID005748312
DrugPCB74

RYR1 RYR2 RYR3

5.83e-0741213CID000036218
Drug148504-47-6

RYR1 RYR2 RYR3

5.83e-0741213CID006444275
DrugSC 38249

RYR1 RYR2 RYR3

5.83e-0741213CID000134834
DrugAC1L1U7A

RYR1 RYR2 RYR3

5.83e-0741213CID000035682
Drugchloro-m-cresol

RYR1 RYR2 RYR3

2.89e-0661213CID000012008
DrugMBED

RYR1 RYR2 RYR3

2.89e-0661213CID000129958
DrugAC1O528X

RYR1 RYR2 RYR3

2.89e-0661213CID006475857
DrugNSC114784

RYR1 RYR2 RYR3

2.89e-0661213CID000419425
Drug[[(2R,3S,4R)-5-(2-amino-6-oxo-3H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl] [(2R,3S,4R,5R)-3,4,5-trihydroxyoxolan-2-yl]methyl hydrogen phosphate

RYR1 RYR2 RYR3

5.05e-0671213CID009547999
DrugAzumoleno

RYR1 RYR2 RYR3

5.05e-0671213CID000056259
DrugBr2BAPTA

RYR1 RYR2 RYR3

5.05e-0671213CID003081001
DrugT0702

RYR1 RYR2 RYR3 PLTP

8.81e-06251214CID000005908
DrugPCB 95

RYR1 RYR2 RYR3

1.71e-05101213CID000038012
DrugPCB 66

RYR1 RYR2 RYR3

2.34e-05111213CID000036185
DrugR 478

RYR1 RYR2 RYR3

2.34e-05111213CID000084223
Drug8-amino-cADPR

RYR1 RYR2 RYR3

2.34e-05111213CID003081323
Drug5'-adenylyl (beta,gamma-methylene)diphosphonate

RYR1 RYR3

2.80e-0521212ctd:C005147
DrugRyanodine

RYR1 RYR2 RYR3

3.11e-05121213ctd:D012433
DrugFPL 64176

RYR1 RYR2 RYR3

6.36e-05151213CID000003423
DrugGvapspat amide

RYR1 RYR2 RYR3

6.36e-05151213CID000125015
Drug1,1'-diheptyl-4,4'-bipyridinium

RYR1 RYR3

8.37e-0531212CID000080262
Drugflubendiamide

RYR1 RYR3

8.37e-0531212CID011193251
DrugNalbuphine hydrochloride [23277-43-2]; Up 200; 10.2uM; MCF7; HT_HG-U133A

VEZT ADAMTS5 PTGIS RYR1 SATB1 OR7A10 DOP1B

8.41e-0519512172225_UP
DrugCarbinoxamine maleate salt [3505-38-2]; Down 200; 9.8uM; PC3; HT_HG-U133A

WDR19 HEATR6 SLC2A6 KLHL21 DENND4B VPS13A DOP1B

8.97e-0519712177138_DN
Drugkazinol B

RYR1 RYR2 RYR3

9.43e-05171213CID000480869
Drugketene

TMC1 INTS5 SLC38A3

9.43e-05171213CID000010038
DrugPHA-00851261E [724719-49-7]; Up 200; 1uM; PC3; HT_HG-U133A

PGAP3 FSTL4 ZIM2 MMP15 FMNL1 RAPGEFL1 DOP1B

9.85e-0520012173776_UP
Drugmethylcoumarin

RYR1 RYR2 RYR3

1.13e-04181213CID000007092
DrugAC1MW7VF

RYR1 RYR2 RYR3

1.33e-04191213CID000414699
DrugAC1L380G

RYR1 RYR2 RYR3

1.33e-04191213CID000084698
Diseasecongenital myopathy 1A (implicated_via_orthology)

RYR1 RYR2 RYR3

5.04e-0831103DOID:3529 (implicated_via_orthology)
Diseasemalignant hyperthermia (implicated_via_orthology)

RYR1 RYR2 RYR3

5.04e-0831103DOID:8545 (implicated_via_orthology)
Diseasemegaloblastic anemia (is_implicated_in)

TCN2 SLC19A2

4.12e-0531102DOID:13382 (is_implicated_in)
Diseaselipid storage disease (implicated_via_orthology)

PSAP SLC7A3

8.22e-0541102DOID:9455 (implicated_via_orthology)
Diseasepulmonary hypertension (biomarker_via_orthology)

SLC2A4 RYR1 RYR2 RYR3

2.33e-04801104DOID:6432 (biomarker_via_orthology)
DiseaseKunitz-type protease inhibitor 2 measurement

RYR1 KCNK6

6.08e-04101102EFO_0008200
DiseaseLiver Cirrhosis, Experimental

SLC19A2 NRROS ACOX2 MINDY3 FRY ADRA1B MMP15 FMNL1 PLTP SP140

6.46e-0477411010C0023893
DiseaseCongenital muscular dystrophy

LAMA2 RYR1

8.87e-04121102cv:C0699743
Diseaseisoleucine measurement

LAMA2 SLC2A4 FARS2

1.21e-03561103EFO_0009793
Diseasetea consumption measurement

LAMA2 KCNB2 PLEKHH3 SLC38A3

1.41e-031291104EFO_0010091
Diseasecalcium/calmodulin-dependent protein kinase type 1 measurement

SLC19A2 CPNE1

1.60e-03161102EFO_0008062
Diseaseaspartate aminotransferase measurement

SPPL3 FSTL4 SLC2A4 ACOX2 GLB1 CPNE1 LRBA MERTK MMP15 CDK6

2.06e-0390411010EFO_0004736
Diseaseresponse to supplemental oxygen

FSTL4 PLPPR5

2.26e-03191102EFO_0009796
Diseasespermatogenic failure (is_implicated_in)

WDR19 MOV10L1

3.31e-03231102DOID:0111910 (is_implicated_in)
Diseasediacylglycerol 34:1 measurement

NLRP7 ZNF254

3.60e-03241102EFO_0010352

Protein segments in the cluster

PeptideGeneStartEntry
MSNLRELFLAFGYER

PRAMEF33

231

A0A0G2JMD5
FLSGAQVDMARTAYL

ACOX2

596

Q99424
FYAGDLLMSVEILRN

ADGRB3

611

O60242
LLLVADASMARLYGR

ADAMTS5

271

Q9UNA0
YLSLLRALDNGMGDL

ABCA12

1631

Q86UK0
GMAFLAAVALDRYLR

GPR31

101

O00270
TQALLAYIFSLAGEM

A2ML1

1136

A8K2U0
AYIFSLAGEMDIRNI

A2ML1

1141

A8K2U0
YMELQQRLLAGGLFS

BNC1

671

Q01954
NYFIVNLAMADLLLS

ADRA1B

81

P35368
MANSGLQLLGYFLAL

CLDN19

1

Q8N6F1
LLAARLVTFLMDNYQ

DEPDC1B

376

Q8WUY9
LSFLLVLDYIGINMA

EDNRB

361

P24530
AAALGVQDYLLFAEM

ADCK5

416

Q3MIX3
LADFGLARIYSFQMA

CDK6

161

Q00534
VVAMSRARLGLYIFA

AQR

1291

O60306
LVAIFFGMALYLRSL

DISP2

496

A7MBM2
EGLLLVVMAFDRYIA

OR4N4C

111

A0A096LPK9
MRRGALLAGALAAYA

KCNK6

1

Q9Y257
LLSRYLTLDGFDAMF

CYFIP1

811

Q7L576
ATLLGLANMETRYFA

NUP133

951

Q8WUM0
SSLSLDLFMLGYFQL

ESPNL

851

Q6ZVH7
QAAVGFLTLMEALRY

MINDY3

251

Q9H8M7
ARMNLAIALTAARYG

GPD2

226

P43304
RLAMAYGLNVSFLER

MOV10L1

926

Q9BXT6
NILNRATLILDMFYG

MAGEE2

351

Q8TD90
GLVYLRRSNMEFLFN

MAGT1

201

Q9H0U3
DIALGMEYLSNRNFL

MERTK

706

Q12866
SNFLIFYLLMDGLSA

MYO16

591

Q9Y6X6
AAASYEMLILGRFLI

SLC2A4

131

P14672
GYFLLLSMLNDFVTR

DOP1B

1801

Q9Y3R5
AQILASALAEMQRFY

MMP15

76

P51511
ILARGASVNLYMFIG

GLB1

296

P16278
MALQEAREAYLVGLF

H3-7

91

Q5TEC6
RLSQGFLLDYFLMSL

PCNX3

1216

Q9H6A9
MCLAFLTGLNRVAEY

PLPPR5

231

Q32ZL2
AMESYFRAGALQLLL

PLTP

276

P55058
SNMREFLLLEYASGL

NUP85

396

Q9BW27
EGLLLVVMAFDRYIA

OR4N2

111

Q8NGD1
EGLLLVVMAFDRYIA

OR4N4

111

Q8N0Y3
ALQVLTLLARGYFSM

HEATR6

691

Q6AI08
LMFLNTIAGRSYNDL

LRBA

2226

P50851
MSYDVLFQRTELGAL

LMO7

16

Q8WWI1
LQITYSFGMDAIFRL

LAMA2

686

P24043
AFELMRSNAALFQLG

NLRP2

381

Q9NX02
DGLLNRYILMAFQNS

PAXBP1

801

Q9Y5B6
FYFCRLLLDDLGMNS

RALGAPA2

1601

Q2PPJ7
AAIMFAANLTLGLYI

SLC2A6

346

Q9UGQ3
GYLMDLINFLRSIFQ

EXOC6

631

Q8TAG9
SMFLARVLIGDYING

PARP11

276

Q9NR21
KGIYALAARDVFLML

KIF2A

336

O00139
RSYNELGLLILFLAM

KCNB1

326

Q14721
MLQLLLDFSYTGRVA

KLHL21

86

Q9UJP4
SYNELGLLILFLAMG

KCNB2

331

Q92953
ASASLYLLMRQNFEI

DOCK6

1481

Q96HP0
LYDLLSLMDRGFVFN

DOCK8

1056

Q8NF50
ALSNVQRLTFYGFLM

CSTPP1

226

Q9H6J7
LMGALLASLIYNFVL

AQP6

221

Q13520
LRVQFYVSRLMEALG

FNIP2

366

Q9P278
AGFLRYISMQNLAVI

ARFGEF3

1756

Q5TH69
TMAGYARLKNVLLAL

FSTL4

141

Q6MZW2
LALDNMLYFSRNAPS

ELMO3

366

Q96BJ8
AGAFYALSTLLNRMV

FLVCR2

321

Q9UPI3
AYGFRLQSLDALLEM

FMNL1

856

O95466
QRGIYREILFLTMAA

DENND4B

1426

O75064
LGALFLEYVDLTRML

FRY

1061

Q5TBA9
IAANLSMERYALVFG

SLC19A2

411

O60779
AIMSFYAALIDLLGR

RYR1

2421

P21817
NAIMTFYSALIDLLG

RYR2

2386

Q92736
ALSATDMALALNRYL

RYR2

2506

Q92736
EMEYSGANSIFLRLL

BYSL

331

Q13895
YAMAEDGLLFRVLAR

SLC7A3

361

Q8WY07
ASQYFMLLLLTDGAV

CPNE1

411

Q99829
TLLLRDNNMGFYRDL

NRROS

276

Q86YC3
SFLNGLASLVMLCRY

PGAP3

111

Q96FM1
VFGNIDSYLLAAMAI

OR1L3

106

Q8NH93
FSLMYAINISGNLAI

OR1Q1

31

Q15612
GVLFLLIYLAALMSN

OR14A2

26

Q96R54
GLLLTSMAYDRYLAI

OR2L13

111

Q8N349
AFRDLGRLMTLYLFA

RTN4R

221

Q9BZR6
GRLMTLYLFANNLSA

RTN4R

226

Q9BZR6
MRLAAAANEAYTAPL

SESN1

1

Q9Y6P5
GRAEAMAAYLALAAQ

PLEKHH3

641

Q7Z736
GLAYAMANTGIILFL

SLC38A3

86

Q99624
EMGLLDFSYSFLLRA

PTGIS

161

Q16647
FLLIYGVTLLANLGM

OR5L1

31

Q8NGL2
LFVGLDNFLLTVMAY

OR7A10

106

O76100
ALLYMAALGATLFAA

SFT2D3

146

Q587I9
FQMLDTLSLYQGLLS

SNX33

466

Q8WV41
AFELMRSNAALFQLG

NLRP7

346

Q8WX94
LLAGHLAMFTNDYNL

WDR19

721

Q8NEZ3
AGAYRLLQFLVDTAM

INTS5

401

Q6P9B9
MRRNAFSIYILNLAA

MRGPRX1

56

Q96LB2
GSFLYDARLQALVVM

SEMA4C

601

Q9C0C4
YILNLAIADELFMLG

SSTR2

81

P30874
FLLIYGVTLLANLGM

OR5L2

31

Q8NGL0
LFNQLIEMALLSLGY

SATB1

106

Q01826
SMGQLALYLLALRAN

TCN2

101

P20062
RSNNFYLGMLLLILF

TMC1

631

Q8TDI8
GVMEYDLSLRFLENA

CLUH

1116

O75153
ARTVMLFNLGSAYCL

CNOT10

641

Q9H9A5
YERVQMLLSDRFLGF

PRPF8

2256

Q6P2Q9
MLENYRNLVFLGIAA

ZNF676

1

Q8N7Q3
MDLRLDLGFIYALTD

VPS13A

2711

Q96RL7
RALYRSVMLENFGNL

ZNF19

36

P17023
MSFYSALIDLLGRCA

RYR3

2286

Q15413
LLRFASDAANGMQYL

TIE1

956

P35590
LLIVYGSFRSLNMDF

SPPL3

26

Q8TCT6
RLGQDALLDLSFAYM

TAPBP

171

O15533
MSNLRELFLAFGYER

PRAMEF10

231

O60809
FFLATLLIGLAMRLY

SLC35A4

306

Q96G79
ARVELLMTYFIQLGF

RHPN2P1

81

A8MT19
SLYLINFLLDATVGM

STIMATE

101

Q86TL2
MYALFLLASLLGAAL

PSAP

1

P07602
GHFDYQSLLMRLGLI

UBE2Z

306

Q9H832
DNMENYRKLLSLGFL

ZIM2

121

Q9NZV7
VMLENYRNLAFLGIA

ZNF91

41

Q05481
FNSLVNMAYTLLGLS

TMEM187

56

Q14656
LLCLFLRQLAGAMAY

TNK1

221

Q13470
LEALFSRINLMAYPD

SP140

111

Q13342
AARRALQYLKIMAGS

TARBP2

351

Q15633
ALFLGNLYTFLLALM

TMC2

511

Q8TDI7
LRANFQAARLATLYM

VEZT

266

Q9HBM0
GFTLLLSLLAFAMYR

TMUB1

231

Q9BVT8
DLLSFYAVVMGLDNA

RAPGEFL1

511

Q9UHV5
AFGLGLERLAMILYD

FARS2

311

O95363
VMLENYRNLAFLGIA

ZNF254

41

O75437
AYADFLALDISMLRL

XKR8

121

Q9H6D3