Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyBiologicalProcessintermediate filament organization

KRT26 EPPK1 KRT16 KRT19 PLEC

1.82e-0575895GO:0045109
GeneOntologyBiologicalProcessneuromuscular process

MYH10 ATXN2 NPAS3 ADCY5 RBFOX2 ITPR1 NPAS1

5.40e-05225897GO:0050905
GeneOntologyBiologicalProcessintermediate filament cytoskeleton organization

KRT26 EPPK1 KRT16 KRT19 PLEC

6.94e-0599895GO:0045104
GeneOntologyBiologicalProcessintermediate filament-based process

KRT26 EPPK1 KRT16 KRT19 PLEC

7.28e-05100895GO:0045103
GeneOntologyCellularComponentintermediate filament cytoskeleton

DLGAP2 KRT26 EPPK1 KRT16 KRT19 SYNE2 NCKIPSD PKN2 PLEC

1.82e-06263899GO:0045111
GeneOntologyCellularComponenthemidesmosome

EPPK1 LAMA3 PLEC

1.20e-0511893GO:0030056
GeneOntologyCellularComponentintermediate filament

DLGAP2 KRT26 EPPK1 KRT16 KRT19 NCKIPSD PLEC

5.26e-05227897GO:0005882
GeneOntologyCellularComponentsupramolecular fiber

DLGAP2 KRT26 HABP4 MYH10 EPPK1 KRT16 XIRP2 KRT19 AMOT SYNE2 NCKIPSD CAPZB TOGARAM1 PLEC SMTN

1.27e-0411798915GO:0099512
GeneOntologyCellularComponentsarcoplasm

HABP4 MYH10 SYNE2 PLEC ITPR1

1.27e-04114895GO:0016528
GeneOntologyCellularComponentsupramolecular polymer

DLGAP2 KRT26 HABP4 MYH10 EPPK1 KRT16 XIRP2 KRT19 AMOT SYNE2 NCKIPSD CAPZB TOGARAM1 PLEC SMTN

1.37e-0411878915GO:0099081
GeneOntologyCellularComponentactin cytoskeleton

MYH10 XIRP2 KRT19 AMOT SPTB DDR2 CAPZB ANKRD26 TLN2 SMTN

1.68e-045768910GO:0015629
GeneOntologyCellularComponentcell-substrate junction

EPPK1 XIRP2 CAPN1 SYNE2 DDR2 LAMA3 TLN2 PLEC

6.03e-04443898GO:0030055
GeneOntologyCellularComponentsarcomere

HABP4 XIRP2 KRT19 SYNE2 CAPZB PLEC

6.85e-04249896GO:0030017
GeneOntologyCellularComponentanchoring junction

EPPK1 MAPK15 XIRP2 AMOT CAPN1 SYNE2 DDR2 LAMA3 ANO7 TLN2 PKN2 PLEC

8.66e-049768912GO:0070161
GeneOntologyCellularComponentdendrite

DLGAP2 MYH10 RAP1GAP SACS PPFIA2 LRFN3 CAPZB XRN1 PLEC SCGN ITPR1

1.03e-038588911GO:0030425
GeneOntologyCellularComponentdendritic tree

DLGAP2 MYH10 RAP1GAP SACS PPFIA2 LRFN3 CAPZB XRN1 PLEC SCGN ITPR1

1.05e-038608911GO:0097447
GeneOntologyCellularComponentmyofibril

HABP4 XIRP2 KRT19 SYNE2 CAPZB PLEC

1.10e-03273896GO:0030016
GeneOntologyCellularComponentpost-mRNA release spliceosomal complex

CWF19L2 GCFC2

1.15e-0312892GO:0071014
GeneOntologyCellularComponentcontractile muscle fiber

HABP4 XIRP2 KRT19 SYNE2 CAPZB PLEC

1.50e-03290896GO:0043292
MousePhenopostnatal lethality, incomplete penetrance

GPI MYH10 KRT16 SMC3 SPEF2 BRD4 SPTB SREBF1 NPAS3 UBR3 ZFHX3 XPNPEP1 ITPR1 SMTN

7.74e-066697314MP:0011086
MousePhenopostnatal lethality

GPI MYH10 KRT16 SMC3 XIRP2 SPEF2 BRD4 SPTB SREBF1 NPAS3 LAMA3 UBR3 ZFHX3 IRS1 XPNPEP1 PLEC ITPR1 SMTN

8.15e-0610847318MP:0002082
DomainCH

SPEF2 SPTB SYNE2 PLEC SMTN

2.69e-0573905PS50021
DomainCH-domain

SPEF2 SPTB SYNE2 PLEC SMTN

3.07e-0575905IPR001715
DomainActinin_actin-bd_CS

SPTB SYNE2 PLEC

1.79e-0423903IPR001589
DomainPAS_fold_3

NPAS3 SIM1 NPAS1

1.79e-0423903IPR013655
DomainPAS_3

NPAS3 SIM1 NPAS1

1.79e-0423903PF08447
DomainACTININ_2

SPTB SYNE2 PLEC

1.79e-0423903PS00020
DomainACTININ_1

SPTB SYNE2 PLEC

1.79e-0423903PS00019
DomainPAS-assoc_C

NPAS3 SIM1 NPAS1

2.04e-0424903IPR000700
Domain-

PKN2 PKN3

2.27e-0459021.10.287.160
DomainPAS

NPAS3 SIM1 NPAS1

2.30e-0425903PF00989
DomainPAS_fold

NPAS3 SIM1 NPAS1

2.30e-0425903IPR013767
DomainPAC

NPAS3 SIM1 NPAS1

2.60e-0426903IPR001610
DomainPAC

NPAS3 SIM1 NPAS1

2.60e-0426903SM00086
DomainPAC

NPAS3 SIM1 NPAS1

2.60e-0426903PS50113
DomainCH

SPTB SYNE2 PLEC SMTN

2.73e-0465904SM00033
Domain-

EPPK1 PLEC

3.40e-0469023.90.1290.10
DomainSpectrin_repeat

SPTB SYNE2 PLEC

3.61e-0429903IPR002017
DomainCH

SPTB SYNE2 PLEC SMTN

3.63e-0470904PF00307
Domain-

SPTB SYNE2 PLEC SMTN

3.83e-04719041.10.418.10
DomainPlectin_repeat

EPPK1 PLEC

4.75e-047902IPR001101
DomainHr1

PKN2 PKN3

4.75e-047902SM00742
DomainPlectin

EPPK1 PLEC

4.75e-047902PF00681
DomainSIX1_SD

SIX2 SIX6

4.75e-047902PF16878
DomainSIX1_SD

SIX2 SIX6

4.75e-047902IPR031701
DomainPLEC

EPPK1 PLEC

4.75e-047902SM00250
DomainSpectrin/alpha-actinin

SPTB SYNE2 PLEC

4.85e-0432903IPR018159
DomainPAS

NPAS3 SIM1 NPAS1

4.85e-0432903SM00091
DomainSPEC

SPTB SYNE2 PLEC

4.85e-0432903SM00150
DomainPAS

NPAS3 SIM1 NPAS1

5.81e-0434903IPR000014
DomainPAS

NPAS3 SIM1 NPAS1

5.81e-0434903PS50112
DomainHR1

PKN2 PKN3

6.31e-048902PF02185
DomainKeratin_I

KRT26 KRT16 KRT19

1.24e-0344903IPR002957
DomainAnkyrin_rpt

TRPM4 ANKRD11 ANKRD26 ANKRD28 ANKRD12 ABTB2

1.68e-03262906IPR002110
Domain-

SREBF1 NPAS3 SIM1 NPAS1

1.91e-031099044.10.280.10
DomainIRS_PTB

TLN2 IRS1

2.01e-0314902IPR002404
DomainIRS

TLN2 IRS1

2.01e-0314902PF02174
DomainHLH

SREBF1 NPAS3 SIM1 NPAS1

2.04e-03111904PF00010
DomainHLH

SREBF1 NPAS3 SIM1 NPAS1

2.39e-03116904SM00353
DomainBHLH

SREBF1 NPAS3 SIM1 NPAS1

2.47e-03117904PS50888
DomainbHLH_dom

SREBF1 NPAS3 SIM1 NPAS1

2.55e-03118904IPR011598
DomainAnk_2

ANKRD11 ANKRD26 ANKRD28 ANKRD12 ABTB2

3.84e-03215905PF12796
Domain-

MLH3 SACS

4.12e-03209023.30.565.10
DomainHATPase_C

MLH3 SACS

4.54e-0321902IPR003594
Pubmed

KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.

GPI DLGAP2 ATAD3B MYH10 RAP1GAP KRT16 RTCB SACS KRT19 AMOT PPFIA2 SPTB NCKIPSD CAPZB KBTBD11 XRN1 TLN2 PLEC PRPF40A STRIP1

5.53e-101431902037142655
Pubmed

A central chaperone-like role for 14-3-3 proteins in human cells.

RAP1GAP RTCB KRT19 AMOT BRD4 SYNE2 NCKIPSD CAPZB XRN1 ANKRD11 ANKRD26 IRS1 PLEC ABTB2

4.63e-08861901436931259
Pubmed

NPAS1-ARNT and NPAS3-ARNT crystal structures implicate the bHLH-PAS family as multi-ligand binding transcription factors.

NPAS3 SIM1 NPAS1

5.82e-07790327782878
Pubmed

In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.

CCNH ATAD3B MYH10 KRT16 SACS KRT19 PPFIA2 SPEF2 CNTRL SYNE2 SERF2 CEP83 CAPZB XRN1 ANKRD26 PLEC

8.32e-071442901635575683
Pubmed

Interaction of amyotrophic lateral sclerosis/frontotemporal lobar degeneration-associated fused-in-sarcoma with proteins involved in metabolic and protein degradation pathways.

GPI TRPM4 MYH10 RTCB AMOT DHX40 FANCM

9.66e-0720190725192599
Pubmed

Transcription factor protein interactomes reveal genetic determinants in heart disease.

ATAD3B RTCB SMC3 AMOT BRD4 SIN3A PRPF40A LIN9 RBFOX2

1.25e-0641190935182466
Pubmed

Transgenic mouse proteomics identifies new 14-3-3-associated proteins involved in cytoskeletal rearrangements and cell signaling.

ATAD3B MYH10 PPFIA2 CAPZB PLEC ITPR1

2.39e-0614790616959763
Pubmed

Human transcription factor protein interaction networks.

MEAF6 ATAD3B MYH10 RTCB SMC3 ATXN2 DHX40 SYNE2 XRN1 ANKRD28 ZFHX3 SIN3A PRPF40A LIN9 GADD45GIP1

3.77e-061429901535140242
Pubmed

Hereditary Ataxia Overview

SACS ATXN2 CAPN1 ZFHX3 ITPR1

4.27e-069290520301317
Pubmed

UBE2O promotes lipid metabolic reprogramming and liver cancer progression by mediating HADHA ubiquitination.

CWF19L2 HABP4 ATAD3B MYH10 RTCB AMOT DHX40 CAPZB RBFOX2

5.32e-0649190936273042
Pubmed

Defining the proximal interaction networks of Arf GTPases reveals a mechanism for the regulation of PLD1 and PI4KB.

GPI KRT16 KRT19 AMOT CNTRL KBTBD11 XRN1 ANKRD26 ANKRD28 ZFHX3 STRIP1

5.40e-06777901135844135
Pubmed

mTOR Inhibition via Rapamycin Treatment Partially Reverts the Deficit in Energy Metabolism Caused by FH Loss in RPE Cells.

ATAD3B SMC3 SPTB SYNE2 ANKRD12

5.83e-069890534943047
Pubmed

Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.

TRPM4 ATAD3B MYH10 DCAF8 ATXN2 PPFIA2 SPTB UVSSA CAPN1 ANKRD11 LAMA3 ZFHX3 ANKRD12 ARIH1 RBFOX2

6.19e-061489901528611215
Pubmed

DNA-binding and regulation mechanisms of the SIX family of retinal determination proteins.

SIX2 SIX6

6.62e-06290218293925
Pubmed

AT motif binding factor 1 (ATBF1) is highly phosphorylated in embryonic brain and protected from cleavage by calpain-1.

CAPN1 ZFHX3

6.62e-06290223022192
Pubmed

Plakins in development and disease.

EPPK1 PLEC

6.62e-06290217499243
Pubmed

Novel autosomal recessive LAMA3 and PLEC variants underlie junctional epidermolysis bullosa generalized intermediate and epidermolysis bullosa simplex with muscular dystrophy in two consanguineous families.

LAMA3 PLEC

6.62e-06290229797489
Pubmed

Necessity of inositol (1,4,5)-trisphosphate receptor 1 and mu-calpain in NO-induced osteoclast motility.

CAPN1 ITPR1

6.62e-06290217690304
Pubmed

Neuronal PAS Domain Proteins 1 and 3 Are Master Regulators of Neuropsychiatric Risk Genes.

NPAS3 NPAS1

6.62e-06290228499489
Pubmed

Regulation of epidermal differentiation through KDF1-mediated deubiquitination of IKKα.

ATXN2 AMOT DHX40 XRN1 SIN3A PRPF40A

8.18e-0618290632239614
Pubmed

Synaptic GAP and GEF Complexes Cluster Proteins Essential for GTP Signaling.

DLGAP2 ATAD3B SACS PPFIA2 KBTBD11 TLN2 PKN2

8.79e-0628190728706196
Pubmed

Defining the human deubiquitinating enzyme interaction landscape.

ATAD3B MYH10 SMC3 KRT19 AMOT DHX40 CAPZB ANKRD28 PKN2 PLEC ARIH1 STRIP1

1.10e-051005901219615732
Pubmed

The human cytoplasmic dynein interactome reveals novel activators of motility.

MYH10 KRT19 DHX40 CNTRL CAPZB XRN1 ANKRD26 ANKRD28 NKAP PLEC RBFOX2

1.29e-05853901128718761
Pubmed

Identifying biological pathways that underlie primordial short stature using network analysis.

GPI EPPK1 KRT16 RTCB SACS SMC3 AMOT SYNE2 CAPZB PLEC PRPF40A GADD45GIP1

1.32e-051024901224711643
Pubmed

Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.

AMOT BRD4 XRN1 ANKRD28 ZFHX3 PLEC LIN9 ZMYM5

1.34e-0541890834709266
Pubmed

DNA polymerase POLD1 promotes proliferation and metastasis of bladder cancer by stabilizing MYC.

ATAD3B CAPN1 NKAP PRPF40A ITPR1

1.44e-0511890537105989
Pubmed

A genome-wide screen to identify transcription factors expressed in pelvic Ganglia of the lower urinary tract.

HOXB7 ZMAT5 BRD4 SREBF1 NPAS3 ZFHX3 SIM1 SIX2 ABTB2 SIX6

1.54e-05709901022988430
Pubmed

The deubiquitinase TRABID stabilizes the K29/K48-specific E3 ubiquitin ligase HECTD1.

TRPM4 DCAF8 SMC3 XRN1 ARIH1 STRIP1

1.94e-0521290633853758
Pubmed

FOX-2 dependent splicing of ataxin-2 transcript is affected by ataxin-1 overexpression.

ATXN2 RBFOX2

1.98e-05390222666429
Pubmed

Plakins: a family of versatile cytolinker proteins.

EPPK1 PLEC

1.98e-05390211854008
Pubmed

The neuronal PAS domain protein 3 transcription factor controls FGF-mediated adult hippocampal neurogenesis in mice.

NPAS3 NPAS1

1.98e-05390216172381
Pubmed

Behavioral and regulatory abnormalities in mice deficient in the NPAS1 and NPAS3 transcription factors.

NPAS3 NPAS1

1.98e-05390215347806
Pubmed

Epiplakin deficiency aggravates murine caerulein-induced acute pancreatitis and favors the formation of acinar keratin granules.

EPPK1 KRT19

1.98e-05390225232867
Pubmed

Regulatory domain selectivity in the cell-type specific PKN-dependence of cell migration.

PKN2 PKN3

1.98e-05390221754995
Pubmed

Enzyme kinetics and distinct modulation of the protein kinase N family of kinases by lipid activators and small molecule inhibitors.

PKN2 PKN3

1.98e-05390227919031
Pubmed

RNF38 suppress growth and metastasis via ubiquitination of ACTN4 in nasopharyngeal carcinoma.

MYH10 KRT16 CAPZB PLEC

2.09e-056290435568845
Pubmed

Comprehensive Interactome Mapping of the DNA Repair Scaffold SLX4 Using Proximity Labeling and Affinity Purification.

CWF19L2 ATAD3B MLH3 SMC3 DHX40 BRD4

2.52e-0522290637071664
Pubmed

CDK7/GRP78 signaling axis contributes to tumor growth and metastasis in osteosarcoma.

CCNH HABP4 MYH10 RTCB CNTRL CAPZB ANKRD11 PLEC

2.99e-0546890836042349
Pubmed

Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.

MEAF6 ATAD3B MLH3 DCAF8 BRD4 XRN1 ANKRD28 ZFHX3 SIN3A NKAP PRPF40A GADD45GIP1

3.07e-051116901231753913
Pubmed

Large-scale characterization of HeLa cell nuclear phosphoproteins.

GCFC2 BRD4 TLN2 PKN2 SIN3A NKAP PLEC PRPF40A STRIP1 SMTN

3.24e-05774901015302935
Pubmed

Prothymosin-α enhances phosphatase and tensin homolog expression and binds with tripartite motif-containing protein 21 to regulate Kelch-like ECH-associated protein 1/nuclear factor erythroid 2-related factor 2 signaling in human bladder cancer.

MYH10 KRT16 KRT19

3.26e-052490330719818
Pubmed

Increased insulin receptor substrate 2 expression is associated with steatohepatitis and altered lipid metabolism in obese subjects.

SREBF1 IRS1

3.96e-05490223147115
Pubmed

High-resolution mapping and transcript identification at the progressive epilepsy with mental retardation locus on chromosome 8p.

DLGAP2 KBTBD11

3.96e-0549029314494
Pubmed

STEF/TIAM2-mediated Rac1 activity at the nuclear envelope regulates the perinuclear actin cap.

MYH10 SYNE2

3.96e-05490229844364
Pubmed

Tex19.1 inhibits the N-end rule pathway and maintains acetylated SMC3 cohesin and sister chromatid cohesion in oocytes.

SMC3 UBR3

3.96e-05490232232464
Pubmed

Binding of the SARS-CoV-2 envelope E protein to human BRD4 is essential for infection.

MEAF6 BRD4

3.96e-05490235716662
Pubmed

Slowed conduction and thin myelination of peripheral nerves associated with mutant rho Guanine-nucleotide exchange factor 10.

DLGAP2 KBTBD11

3.96e-05490214508709
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

ATAD3B RAP1GAP TRPM3 SACS ANKRD26 UBR3 TOGARAM1 FANCM

4.32e-0549390815368895
Pubmed

Loss of ER retention motif of AGR2 can impact mTORC signaling and promote cancer metastasis.

GPI MYH10 EPPK1 RTCB CAPN1 CNTRL CAPZB ZFHX3 XPNPEP1 PLEC

4.60e-05807901030575818
Pubmed

Wnt regulation: exploring Axin-Disheveled interactions and defining mechanisms by which the SCF E3 ubiquitin ligase is recruited to the destruction complex.

ATAD3B MYH10 RTCB SMC3 ATXN2 AMOT DHX40 CAPZB PLEC PRPF40A

4.69e-05809901032129710
Pubmed

Human ISG15 conjugation targets both IFN-induced and constitutively expressed proteins functioning in diverse cellular pathways.

GPI EPPK1 ATXN2 SIN3A PLEC

4.86e-0515290516009940
Pubmed

Development, maturation, and necessity of transcription factors in the mouse suprachiasmatic nucleus.

ZFHX3 SIM1 NPAS1 SIX6

4.91e-057790421525287
Pubmed

Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.

MYH10 EPPK1 RTCB CAPN1 SYNE2 XRN1 ANKRD28 PLEC PRPF40A

5.01e-0565390922586326
Pubmed

SMYD3 Impedes Small Cell Lung Cancer Sensitivity to Alkylation Damage through RNF113A Methylation-Phosphorylation Cross-talk.

DCAF8 RTCB KRT19 CAPZB SIN3A NKAP PLEC PRPF40A GADD45GIP1

5.13e-0565590935819319
Pubmed

Complementary proteomics strategies capture an ataxin-1 interactome in Neuro-2a cells.

ATAD3B MYH10 KRT16 RTCB KRT19 BRD4 CAPZB NKAP PRPF40A

5.77e-0566590930457570
Pubmed

Stage- and subunit-specific functions of polycomb repressive complex 2 in bladder urothelial formation and regeneration.

MYH10 KRT16 SMTN

5.83e-052990328049658
Pubmed

Identification and characterization of a set of conserved and new regulators of cytoskeletal organization, cell morphology and migration.

CAPZB PRPF40A STRIP1

5.83e-052990321834987
Pubmed

Linking nuclear matrix-localized PIAS1 to chromatin SUMOylation via direct binding of histones H3 and H2A.Z.

MYH10 EPPK1 KRT16 CAPZB PLEC

6.02e-0515990534537242
Pubmed

Fox-3 and PSF interact to activate neural cell-specific alternative splicing.

MYH10 RBFOX2

6.59e-05590221177649
Pubmed

Evolutionary comparison reveals that diverging CTCF sites are signatures of ancestral topological associating domains borders.

SIX2 SIX6

6.59e-05590226034287
Pubmed

Deficiency of the autophagy gene ATG16L1 induces insulin resistance through KLHL9/KLHL13/CUL3-mediated IRS1 degradation.

ATG16L1 IRS1

6.59e-05590231515271
Pubmed

Charting the molecular network of the drug target Bcr-Abl.

ATAD3B MYH10 KRT16 KRT19 NCKIPSD ANKRD28

6.88e-0526690619380743
Pubmed

Embryonic forebrain transcriptome of mice with polyalanine expansion mutations in the ARX homeobox gene.

SACS SIX2 SIX6

7.15e-053190327798109
Pubmed

Insights into the ubiquitin-proteasome system of human embryonic stem cells.

RTCB ANKRD11 SIN3A NKAP PLEC PRPF40A

7.32e-0526990629511261
Pubmed

WDR76 Co-Localizes with Heterochromatin Related Proteins and Rapidly Responds to DNA Damage.

MYH10 EPPK1 RTCB KRT19 BRD4 CAPZB SIN3A

7.57e-0539490727248496
Pubmed

Characterization of the interactome of the human MutL homologues MLH1, PMS1, and PMS2.

ATAD3B SMC3 AMOT XRN1

7.92e-058790417148452
Pubmed

mTORC1 activity regulates post-translational modifications of glycine decarboxylase to modulate glycine metabolism and tumorigenesis.

MYH10 SMC3 ATXN2 AMOT PLEC PRPF40A

8.10e-0527490634244482
Pubmed

Proteomic Analysis of the Spinophilin Interactome in Rodent Striatum Following Psychostimulant Sensitization.

GPI DLGAP2 MYH10 SPTB PLEC ADCY5 ITPR1

8.71e-0540390730562941
Pubmed

SRCAP complex promotes lung cancer progression by reprograming the oncogenic transcription of Hippo-YAP/TAZ signaling pathway.

RTCB AMOT BRD4 CAPZB XRN1 PKN2 SIN3A PRPF40A

9.14e-0554990838280479
Pubmed

Characterization of the Six1 homeobox gene in normal mammary gland morphogenesis.

SIX2 SIX6

9.87e-05690220074369
Pubmed

Cornelia de Lange Syndrome

SMC3 BRD4

9.87e-05690220301283
Pubmed

The expression profile and clinic significance of the SIX family in non-small cell lung cancer.

SIX2 SIX6

9.87e-05690227821176
Pubmed

Junctional Epidermolysis Bullosa

LAMA3 PLEC

9.87e-05690220301304
Pubmed

Dynamic expression of Six family genes in the dental mesenchyme and the epithelial ameloblast stem/progenitor cells during murine tooth development.

SIX2 SIX6

9.87e-05690219900183
Pubmed

MicroRNA-21 deficiency suppresses prostate cancer progression through downregulation of the IRS1-SREBP-1 signaling pathway.

SREBF1 IRS1

9.87e-05690234610416
Pubmed

Six2 regulates Pax9 expression, palatogenesis and craniofacial bone formation.

SIX2 SIX6

9.87e-05690231765609
Pubmed

TorsinA binds the KASH domain of nesprins and participates in linkage between nuclear envelope and cytoskeleton.

SYNE2 PLEC

9.87e-05690218827015
Pubmed

DSSylation, a novel protein modification targets proteins induced by oxidative stress, and facilitates their degradation in cells.

ATXN2 TLN2 SIN3A

1.03e-043590324515614
Pubmed

Protein interactome reveals converging molecular pathways among autism disorders.

DLGAP2 MYH10 PPFIA2 HLA-DRB5 CNTRL NCKIPSD SIN3A RBFOX2

1.05e-0456090821653829
Pubmed

CCT3 acts upstream of YAP and TFCP2 as a potential target and tumour biomarker in liver cancer.

GPI ATAD3B MYH10 KRT16 KRT19 AMOT

1.06e-0428890631501420
Pubmed

Ring finger protein 12 activates AKT signalling to promote the progression of liver cancer by interacting with EGFR.

ATAD3B MYH10 KRT16 RTCB AMOT CAPZB

1.08e-0428990637132043
Pubmed

The functional interactome landscape of the human histone deacetylase family.

GCFC2 SMC3 SYNE2 ANKRD11 ANKRD12 SIN3A

1.08e-0428990623752268
Pubmed

MECP2 directly interacts with RNA polymerase II to modulate transcription in human neurons.

CWF19L2 ZMAT5 MYH10 KRT16 RTCB SACS BRD4 CAPZB PLEC SIM1 PRPF40A

1.11e-041082901138697112
Pubmed

Competitive binding of E3 ligases TRIM26 and WWP2 controls SOX2 in glioblastoma.

GPI ATAD3B RTCB SPTB CAPN1 XRN1 ANKRD26 LAMA3 RBFOX2

1.19e-0473290934732716
Pubmed

The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.

CCNH TRPM4 HABP4 RTCB ATXN2 DHX40 CEP83 XRN1 ANKRD11 ZFHX3 NKAP LIN9 STRIP1

1.24e-041497901331527615
Pubmed

Phylogenetic and expression analysis of the basic helix-loop-helix transcription factor gene family: genomic approach to cellular differentiation.

SREBF1 NPAS3 SIM1 NPAS1

1.26e-049890418557763
Pubmed

Proteome-scale mapping of binding sites in the unstructured regions of the human proteome.

DLGAP2 EPPK1 ATXN2 XIRP2 SIN3A PLEC ZMYM5

1.30e-0443090735044719
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

TRPM4 EPPK1 BRD4 SREBF1 KBTBD11 ANKRD11 TLN2 IRS1 PLEC ABTB2 PKN3

1.33e-041105901135748872
Pubmed

Direct interaction between hnRNP-M and CDC5L/PLRG1 proteins affects alternative splice site choice.

EPPK1 RTCB SMC3 BRD4 TLN2 PKN2 PLEC PRPF40A

1.36e-0458290820467437
Pubmed

Chromatin remodeling complex interacts with ADD1/SREBP1c to mediate insulin-dependent regulation of gene expression.

SREBF1 SIN3A

1.38e-04790217074803
Pubmed

Phosphorylation of distinct sites in MeCP2 modifies cofactor associations and the dynamics of transcriptional regulation.

SMC3 SIN3A

1.38e-04790222615490
Pubmed

N-Terminal Acetyltransferase Naa40p Whereabouts Put into N-Terminal Proteoform Perspective.

GPI MYH10 RTCB XRN1 ANKRD26 ANKRD28 PKN2 SIN3A PRPF40A PKN3

1.53e-04934901033916271
Pubmed

Systematic mapping of genetic interactions for de novo fatty acid synthesis identifies C12orf49 as a regulator of lipid metabolism.

MEAF6 GPI HABP4 MYH10 SMC3 BRD4 SERF2 SREBF1 XRN1 ANKRD11 ECEL1 NKAP

1.59e-041327901232694731
Pubmed

An integrated workflow for charting the human interaction proteome: insights into the PP2A system.

ATAD3B MYH10 CAPZB STRIP1

1.64e-0410590419156129
Pubmed

CHD3 and CHD4 form distinct NuRD complexes with different yet overlapping functionality.

ATAD3B MYH10 KRT16 RTCB SMC3 KRT19 ZFHX3 PRPF40A

1.78e-0460590828977666
Pubmed

The Nse5/6-like SIMC1-SLF2 complex localizes SMC5/6 to viral replication centers.

MEAF6 CWF19L2 ATAD3B RTCB ATXN2 BRD4 SERF2 ANKRD11 FANCM PRPF40A

1.81e-04954901036373674
Pubmed

Six3 and Six6 activity is modulated by members of the groucho family.

SIX2 SIX6

1.84e-04890212441302
Pubmed

Cytokeratin, vimentin and E-cadherin immunodetection in the embryonic palate in two strains of mice with different susceptibility to glucocorticoid-induced clefting.

KRT16 KRT19

1.84e-04890211321598
Pubmed

Characterization of gene regulation and protein interaction networks for Matrin 3 encoding mutations linked to amyotrophic lateral sclerosis and myopathy.

ATAD3B EPPK1 RTCB SMC3

1.90e-0410990429511296
Pubmed

Characterization of the zinc-induced Shank3 interactome of mouse synaptosome.

ATAD3B XIRP2 ZFHX3 ITPR1

1.90e-0410990429111324
InteractionPOLD1 interactions

ATG16L1 ATAD3B RTCB BRD4 CAPN1 CAPZB NKAP ARIH1 PRPF40A ITPR1 NPAS1

3.11e-073379011int:POLD1
InteractionVIM interactions

CWF19L2 HABP4 GCFC2 EPPK1 KRT16 RTCB SACS KRT19 SPEF2 BRD4 CAPN1 CNTRL CAPZB IRS1 PLEC

2.55e-068049015int:VIM
InteractionKCTD13 interactions

GPI DLGAP2 MYH10 RAP1GAP KRT16 RTCB SACS KRT19 AMOT PPFIA2 SPTB NCKIPSD CAPZB KBTBD11 XRN1 TLN2 PLEC ARIH1 PRPF40A STRIP1

2.61e-0613949020int:KCTD13
InteractionKHDRBS1 interactions

ATG16L1 ATXN2 BRD4 NCKIPSD CAPZB SREBF1 IRS1 SIN3A PLEC RBFOX2

6.42e-063739010int:KHDRBS1
InteractionDES interactions

CWF19L2 KRT16 XIRP2 KRT19 CAPN1 ABTB2 ZMYM5

6.90e-06158907int:DES
InteractionANKRD50 interactions

ATG16L1 HABP4 CAPZB ANKRD28 NKAP PRPF40A

8.90e-06108906int:ANKRD50
InteractionFOXK1 interactions

AMOT BRD4 DDR2 ANKRD28 SIN3A PLEC ARIH1 NPAS1

1.13e-05238908int:FOXK1
InteractionPLEKHG1 interactions

ATG16L1 KRT19 AMOT ANKRD28 XPNPEP1

1.23e-0567905int:PLEKHG1
InteractionSMG7 interactions

ATG16L1 GCFC2 ATXN2 KRT19 AMOT UVSSA XRN1 ABTB2 NPAS1

1.28e-05319909int:SMG7
InteractionKIF20A interactions

ATAD3B MYH10 EPPK1 RTCB BRD4 SPTB SYNE2 CAPZB XRN1 PLEC PRPF40A GADD45GIP1 PKN3 RBFOX2 ITPR1 SMTN

1.52e-0510529016int:KIF20A
InteractionSYNCRIP interactions

HABP4 GCFC2 ATXN2 BRD4 UVSSA CAPN1 CAPZB XRN1 ANKRD11 ANKRD28 TLN2 NKAP PRPF40A

1.83e-057219013int:SYNCRIP
InteractionERC1 interactions

ATG16L1 MAPK15 KRT19 AMOT CNTRL SERF2 CAPZB

2.07e-05187907int:ERC1
InteractionCSNK2B interactions

MEAF6 CCNH ATG16L1 CWF19L2 DCAF8 BRD4 CAPZB ANKRD11 ANKRD28 IRS1 NKAP GADD45GIP1

2.15e-056259012int:CSNK2B
InteractionPLEC interactions

ATG16L1 KRT16 SMC3 KRT19 SPEF2 BRD4 SYNE2 PLEC FANCM ITPR1

2.20e-054309010int:PLEC
InteractionNEFM interactions

MYH10 EPPK1 KRT16 KRT19 CAPN1 CAPZB PLEC

2.29e-05190907int:NEFM
InteractionKDF1 interactions

ATXN2 AMOT DHX40 XRN1 UBR3 SIN3A PRPF40A

2.45e-05192907int:KDF1
InteractionYWHAH interactions

ATG16L1 RAP1GAP EPPK1 RTCB KRT19 AMOT BRD4 CNTRL SYNE2 NCKIPSD CAPZB XRN1 ANKRD11 ANKRD26 IRS1 PLEC

2.68e-0511029016int:YWHAH
InteractionCHD3 interactions

HABP4 ATAD3B MYH10 KRT16 RTCB SMC3 KRT19 BRD4 SERF2 ZFHX3 SIN3A PRPF40A LIN9

3.05e-057579013int:CHD3
InteractionCRK interactions

HABP4 KRT16 RTCB KRT19 BRD4 NCKIPSD CAPZB IRS1 PLEC

4.10e-05370909int:CRK
InteractionKRT78 interactions

KRT26 EPPK1 KRT16 KRT19 PLEC

4.40e-0587905int:KRT78
InteractionN4BP2 interactions

ATG16L1 RTCB AMOT PLEC NPAS1

4.90e-0589905int:N4BP2
InteractionKIF7 interactions

ATG16L1 KRT16 KRT19 AMOT CNTRL SMTN

4.92e-05146906int:KIF7
InteractionATXN1 interactions

MYH10 GCFC2 KRT16 RTCB ATXN2 KRT19 BRD4 SYNE2 CAPZB SREBF1 NKAP ARIH1 PRPF40A RBFOX2 STRIP1

5.28e-0510399015int:ATXN1
InteractionSMARCC1 interactions

CCNH ATG16L1 MYH10 BRD4 CAPZB SREBF1 SIN3A PRPF40A STRIP1

5.47e-05384909int:SMARCC1
InteractionWWTR1 interactions

RTCB AMOT BRD4 CAPZB XRN1 PKN2 C1orf74 SIN3A PRPF40A

1.12e-04422909int:WWTR1
InteractionTRIM37 interactions

ATG16L1 CWF19L2 MYH10 EPPK1 KRT19 CAPZB XRN1 ANKRD11 ANKRD12 PLEC SMTN

1.13e-046309011int:TRIM37
InteractionKTN1 interactions

ATG16L1 RTCB KRT19 DHX40 CAPN1 DDR2 CAPZB PKN2

1.17e-04331908int:KTN1
InteractionAR interactions

CCNH MYH10 MLH3 EPPK1 RTCB SMC3 BRD4 CAPZB SREBF1 ZFHX3 SIN3A PRPF40A LIN9 GADD45GIP1

1.23e-049929014int:AR
InteractionPRPF38B interactions

BRD4 CNTRL SERF2 SREBF1 RBFOX2

1.23e-04108905int:PRPF38B
InteractionINA interactions

KRT16 KRT19 BRD4 CAPN1 PLEC ABTB2

1.26e-04173906int:INA
InteractionKRT72 interactions

KRT26 EPPK1 KRT16 KRT19

1.40e-0459904int:KRT72
InteractionTFCP2 interactions

GPI ATAD3B MYH10 KRT16 KRT19 AMOT BRD4 SIN3A NPAS1

1.44e-04436909int:TFCP2
InteractionCEP152 interactions

ATG16L1 KRT19 AMOT CNTRL CAPZB XRN1

1.52e-04179906int:CEP152
InteractionH2BC4 interactions

MYH10 SMC3 DHX40 BRD4 CAPZB XRN1 ANKRD11

1.61e-04259907int:H2BC4
InteractionKRT4 interactions

KRT26 EPPK1 KRT16 KRT19

1.70e-0462904int:KRT4
InteractionENTR1 interactions

ATG16L1 KRT19 AMOT CNTRL CAPZB ANKRD28

1.98e-04188906int:ENTR1
InteractionHOXB7 interactions

HOXB7 GCFC2 UBR3

2.08e-0426903int:HOXB7
InteractionCEP192 interactions

ATG16L1 KRT19 AMOT CNTRL XRN1 ANKRD28

2.22e-04192906int:CEP192
InteractionGRIPAP1 interactions

CCNH ATG16L1 CWF19L2 ANKRD11 PKN3 NPAS1

2.22e-04192906int:GRIPAP1
InteractionBTF3 interactions

ATG16L1 ATAD3B MYH10 RTCB KRT19 BRD4 SPTB CAPZB PKN2 PLEC ITPR1 SMTN

2.22e-047999012int:BTF3
InteractionCDK9 interactions

CCNH ATG16L1 MYH10 RTCB SMC3 KRT19 BRD4 SPTB CAPZB PLEC PRPF40A

2.34e-046859011int:CDK9
InteractionKIAA1671 interactions

KRT19 AMOT CNTRL CAPZB ABTB2 NPAS1

2.34e-04194906int:KIAA1671
InteractionDNMBP interactions

ATG16L1 KRT19 AMOT SYNE2 CAPZB

2.35e-04124905int:DNMBP
InteractionPRMT5 interactions

ATG16L1 MYH10 DCAF8 BRD4 CAPN1 SREBF1 SIN3A PLEC RBFOX2

2.55e-04471909int:PRMT5
InteractionTNRC6B interactions

DLGAP2 ATXN2 KRT19 AMOT CNTRL CAPZB XRN1

2.71e-04282907int:TNRC6B
InteractionPIBF1 interactions

CWF19L2 KRT19 AMOT CNTRL ANKRD28 ZFHX3

2.76e-04200906int:PIBF1
InteractionHNRNPA1 interactions

ATG16L1 EPPK1 KRT16 RTCB ATXN2 BRD4 CAPZB XRN1 ANKRD12 PLEC PRPF40A GADD45GIP1 RBFOX2

2.81e-049459013int:HNRNPA1
InteractionAKR7L interactions

HABP4 GCFC2 DHX40 UBR3

3.03e-0472904int:AKR7L
InteractionTCHP interactions

ATG16L1 KRT16 KRT19 AMOT CNTRL

3.04e-04131905int:TCHP
InteractionANKRD26 interactions

KRT19 AMOT CNTRL ANKRD26 ANKRD28

3.04e-04131905int:ANKRD26
InteractionPRPH interactions

KRT16 RTCB SACS KRT19 PLEC ARIH1

3.07e-04204906int:PRPH
InteractionCSNK2A1 interactions

MEAF6 GPI ATG16L1 HOXB7 GCFC2 ATXN2 BRD4 CAPZB ANKRD11 IRS1 SIN3A NKAP PRPF40A

3.15e-049569013int:CSNK2A1
InteractionSPOP interactions

MEAF6 RTCB KRT19 BRD4 CAPZB PLEC ARIH1 PRPF40A RBFOX2

3.46e-04491909int:SPOP
InteractionAPC interactions

ATG16L1 MYH10 SMC3 KRT19 AMOT LAMA3 ANKRD28 RBFOX2

3.50e-04389908int:APC
InteractionKRT23 interactions

ATG16L1 EPPK1 PLEC

3.54e-0431903int:KRT23
InteractionTHOC1 interactions

ATG16L1 GCFC2 RTCB BRD4 ANO7 PRPF40A

3.59e-04210906int:THOC1
InteractionRLIM interactions

ATAD3B MYH10 KRT16 RTCB AMOT CAPZB SIN3A NPAS1

3.69e-04392908int:RLIM
InteractionKRT6C interactions

KRT26 KRT16 KRT19 PLEC

3.73e-0476904int:KRT6C
InteractionUSP54 interactions

ATG16L1 HABP4 KRT19 NCKIPSD ANKRD11 ABTB2

3.77e-04212906int:USP54
InteractionHDAC1 interactions

ATG16L1 MYH10 RTCB SMC3 AMOT BRD4 SYNE2 SREBF1 XRN1 ANKRD28 ZFHX3 SIN3A PLEC LIN9

3.83e-0411089014int:HDAC1
InteractionSGPL1 interactions

ATG16L1 CNTRL DDR2 CAPZB PKN2 ANKRD12

3.87e-04213906int:SGPL1
InteractionCCZ1 interactions

ATG16L1 CAPZB PRPF40A NPAS1

3.92e-0477904int:CCZ1
InteractionYWHAG interactions

ATG16L1 MYH10 RAP1GAP RTCB KRT19 AMOT SYNE2 NCKIPSD CAPZB ANKRD11 ANKRD26 PKN2 IRS1 NKAP PRPF40A

3.95e-0412489015int:YWHAG
InteractionPPFIA1 interactions

CCNH ATG16L1 AMOT PPFIA2 BRD4 CAPZB

3.96e-04214906int:PPFIA1
InteractionBRCA1 interactions

GPI CCNH CWF19L2 MYH10 SMC3 DHX40 BRD4 CAPZB ANKRD26 ANKRD28 PLEC ARIH1 FANCM ITPR1 SMTN

3.98e-0412499015int:BRCA1
InteractionCDC5L interactions

CWF19L2 EPPK1 RTCB SMC3 DHX40 PPFIA2 BRD4 CAPZB TLN2 PKN2 PLEC PRPF40A

4.11e-048559012int:CDC5L
InteractionCFH interactions

ATAD3B SMC3 SPTB SYNE2 ANKRD12

4.12e-04140905int:CFH
InteractionANKHD1 interactions

MEAF6 HOXB7 MYH10 SIX2 RBFOX2 NPAS1

4.16e-04216906int:ANKHD1
InteractionGOLGA2 interactions

CCNH ATG16L1 CWF19L2 MYH10 SMC3 ANKRD11 ZFHX3 SIN3A GADD45GIP1 PKN3 STRIP1

4.17e-047339011int:GOLGA2
InteractionS100A4 interactions

MYH10 BRD4 CNTRL SYNE2 PKN3

4.69e-04144905int:S100A4
InteractionSIRT7 interactions

MYH10 EPPK1 RTCB BRD4 CAPN1 SYNE2 SERF2 XRN1 ANKRD28 PLEC PRPF40A

4.72e-047449011int:SIRT7
InteractionSNX18 interactions

ATG16L1 BRD4 ANKRD28 ARIH1

4.76e-0481904int:SNX18
InteractionPPP1R9B interactions

GPI DLGAP2 ATG16L1 MYH10 SPTB CAPZB ANKRD28 PLEC ADCY5 ITPR1

4.77e-046269010int:PPP1R9B
InteractionSNW1 interactions

CWF19L2 EPPK1 RTCB SMC3 DHX40 BRD4 PKN2 SIN3A PLEC PRPF40A RBFOX2

4.88e-047479011int:SNW1
InteractionGATA4 interactions

ATAD3B RTCB SMC3 AMOT BRD4 PRPF40A LIN9 RBFOX2

5.04e-04411908int:GATA4
InteractionRPGRIP1L interactions

ATG16L1 EPPK1 SMC3 CNTRL CAPZB ANKRD28

5.17e-04225906int:RPGRIP1L
InteractionFOXK2 interactions

AMOT BRD4 DDR2 ANKRD28 SIN3A NPAS1

5.17e-04225906int:FOXK2
InteractionANKRD17 interactions

MEAF6 HOXB7 ATXN2 CAPN1 CAPZB SIX2

5.29e-04226906int:ANKRD17
InteractionCALCOCO1 interactions

ATG16L1 CWF19L2 KRT16 KRT19

5.46e-0484904int:CALCOCO1
InteractionSMC1A interactions

ATG16L1 CWF19L2 SMC3 AMOT BRD4 ANKRD11 ANKRD28 LIN9

5.63e-04418908int:SMC1A
InteractionKRT74 interactions

KRT26 KRT16 KRT19

6.00e-0437903int:KRT74
InteractionKRT82 interactions

EPPK1 KRT16 KRT19

6.00e-0437903int:KRT82
InteractionSMC2 interactions

ATG16L1 MYH10 SMC3 BRD4 CAPZB SIN3A PLEC

6.10e-04323907int:SMC2
Cytoband17q21.2

KRT26 KRT16 KRT19

3.63e-047090317q21.2
Cytoband14q21.2

TOGARAM1 FANCM

7.06e-042090214q21.2
Cytoband13q12

SACS ZMYM5

1.02e-032490213q12
CytobandEnsembl 112 genes in cytogenetic band chr22q12

ZMAT5 RTCB RBFOX2 SMTN

1.21e-03235904chr22q12
CytobandEnsembl 112 genes in cytogenetic band chr14q23

SPTB SYNE2 SIX6

2.18e-03130903chr14q23
GeneFamilyKeratins, type I

KRT26 KRT16 KRT19

1.07e-0428603608
GeneFamilySINE class homeoboxes

SIX2 SIX6

1.61e-046602525
GeneFamilyEF-hand domain containing|Plakins

EPPK1 PLEC

2.99e-048602939
GeneFamilyC2 domain containing protein kinases

PKN2 PKN3

4.79e-0410602835
GeneFamilyBasic helix-loop-helix proteins

SREBF1 NPAS3 SIM1 NPAS1

4.87e-04110604420
GeneFamilyAnkyrin repeat domain containing

ANKRD11 ANKRD26 ANKRD28 ANKRD12 ABTB2

1.24e-03242605403
GeneFamilyTransient receptor potential cation channels

TRPM4 TRPM3

3.87e-0328602249
CoexpressionDACOSTA_UV_RESPONSE_VIA_ERCC3_DN

SACS SMC3 ATXN2 SYNE2 DDR2 ANKRD28 TOGARAM1 ZFHX3 PKN2 IRS1 ARIH1 DCUN1D4 RBFOX2 ITPR1

1.28e-068569014M4500
CoexpressionBENPORATH_SUZ12_TARGETS

HOXB7 AMOT SPTB PTH2 ANKRD11 LAMA3 ZFHX3 ECEL1 PLEC FAM43B SIX2 ABTB2 NPAS1 SIX6

1.13e-0510359014M9898
CoexpressionBENPORATH_EED_TARGETS

HOXB7 ZMAT5 ATAD3B AMOT PTH2 ZFHX3 ECEL1 PLEC SIM1 FAM43B SIX2 ABTB2 NPAS1 SIX6

1.46e-0510599014M7617
CoexpressionRODRIGUES_THYROID_CARCINOMA_POORLY_DIFFERENTIATED_DN

RAP1GAP DCAF8 ATXN2 UVSSA CAPN1 SYNE2 SERF2 ANKRD28 ZFHX3 IRS1 ZMYM5 ITPR1

2.03e-058079012M16651
CoexpressionMIKKELSEN_NPC_HCP_WITH_H3K27ME3

DLGAP2 HOXB7 ECEL1 SIM1 FAM43B NPAS1 SIX6 NLRP6

2.52e-05345908M2009
CoexpressionMIKKELSEN_NPC_HCP_WITH_H3K27ME3

DLGAP2 HOXB7 ECEL1 SIM1 FAM43B NPAS1 SIX6 NLRP6

2.63e-05347908MM860
CoexpressionMEISSNER_BRAIN_HCP_WITH_H3K27ME3

HOXB7 KRT19 ECEL1 SIM1 SIX2 NPAS1 SIX6

4.30e-05272907M1938
CoexpressionMEISSNER_BRAIN_HCP_WITH_H3K27ME3

HOXB7 KRT19 ECEL1 SIM1 SIX2 NPAS1 SIX6

5.40e-05282907MM822
CoexpressionBENPORATH_PRC2_TARGETS

HOXB7 PTH2 ZFHX3 ECEL1 PLEC FAM43B SIX2 ABTB2 NPAS1 SIX6

7.90e-056509010M8448
CoexpressionAtlasfacebase_RNAseq_e10.5_MaxArch_2500_K3

CWF19L2 MYH10 RAP1GAP SMC3 BRD4 CNTRL SYNE2 CEP83 ANKRD26 UBR3 ZFHX3 C1orf74 ANKRD12 FANCM PRPF40A LIN9 ZMYM5

1.75e-0512529017facebase_RNAseq_e10.5_MaxArch_2500_K3
CoexpressionAtlasfacebase_RNAseq_e10.5_Emin_LatNas_2500_K3

CWF19L2 MYH10 GCFC2 SMC3 DHX40 BRD4 CNTRL SYNE2 CEP83 ANKRD26 ANKRD28 ZFHX3 FANCM DCUN1D4 PRPF40A LIN9 ZMYM5

1.85e-0512579017facebase_RNAseq_e10.5_Emin_LatNas_2500_K3
CoexpressionAtlasfacebase_RNAseq_e10.5_Emin_LatNas_2500

CWF19L2 MYH10 GCFC2 SMC3 DHX40 BRD4 CNTRL SYNE2 CEP83 ANKRD26 ANKRD28 ZFHX3 SIM1 FANCM DCUN1D4 PRPF40A LIN9 ZMYM5

3.44e-0514599018facebase_RNAseq_e10.5_Emin_LatNas_2500
ToppCell(11)_FOXN4+-(2)_GFP_FOXI1|(11)_FOXN4+ / shred by cell type by condition

SMC3 BRD4 CNTRL SYNE2 ANKRD11 ANKRD26 ANKRD12 NKAP PRPF40A

2.68e-1019890976d40b8c2f8399725b3a62ee2ae0896559cf91eb
ToppCell(10)_Ciliated-(2)_GFP_FOXI1|(10)_Ciliated / shred by cell type by condition

SMC3 BRD4 CNTRL SYNE2 ANKRD11 ANKRD26 TOGARAM1 ANKRD12 PRPF40A

2.80e-1019990961b1ed2db71b96157b92b7535d1955a4033098da
ToppCell(09)_Interm._secr.>cil.-(2)_GFP_FOXI1|(09)_Interm._secr.>cil. / shred by cell type by condition

SMC3 BRD4 CNTRL SYNE2 ANKRD11 ANKRD26 ANKRD12 PRPF40A

7.23e-09199908fc680f85ebd3bab4c72876a19a461b0afb5f51ce
ToppCellnucseq-Mesenchymal-Fibroblastic-Fibroblastic_2-ASMC|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

MYH10 SACS PPFIA2 TLN2 ZFHX3 ADCY5 SMTN

6.28e-08173907cb6389536195443633adb06e5f1b7483530773d1
ToppCell(00)_Basal-(2)_GFP_FOXI1|(00)_Basal / shred by cell type by condition

SMC3 BRD4 SYNE2 ANKRD11 ANKRD26 ANKRD12 PRPF40A

1.63e-0719990719674e1eaeb51e4196d847cb62aa437c852951d3
ToppCell(04)_Interm._basal>secr.-(2)_GFP_FOXI1|(04)_Interm._basal>secr. / shred by cell type by condition

SMC3 BRD4 HLA-DRB5 SYNE2 ANKRD11 ANKRD12 PRPF40A

1.63e-0719990753ca3861f9e00dab3f3fbefb0837857ee39ab084
ToppCell(05)_Secretory-(2)_GFP_FOXI1|(05)_Secretory / shred by cell type by condition

SMC3 BRD4 HLA-DRB5 SYNE2 ANKRD11 ANKRD12 PRPF40A

1.63e-07199907d72d87e1e530ed894c0ad5e7b5b2b1d6b59fa098
ToppCellAdult-Mesenchymal-vascular_smooth_muscle_cell-D122|Adult / Lineage, Cell type, age group and donor

HOXB7 MYH10 PPFIA2 SPTB ADCY5 SMTN

8.96e-07160906fd14dfeb7021a4b7299371854dc8fc1fd66c8dae
ToppCelldroplet-Limb_Muscle-MUSCLE-30m|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SMC3 CNTRL SYNE2 XRN1 ANKRD11 PKN2

1.67e-0617890601dafd19de04eff459253eaa9a35debf8f3deedf
ToppCellControl-Fibroblasts-Airway_smooth_muscle|Control / group, cell type (main and fine annotations)

MYH10 PPFIA2 TLN2 ZFHX3 ADCY5 SMTN

1.78e-06180906d0de12749ef0f51f0931c6e7b9b99966bdbc3ec1
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Outer_Medullary_Collecting_Duct_Principal_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

MYH10 TRPM3 KRT19 NPAS3 TLN2 ABTB2

2.08e-06185906d602a9b35e86e6f2a14a58e40fc4fb97f5fa3b08
ToppCelldroplet-Tongue-nan|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SMC3 BRD4 SYNE2 ANKRD11 PKN2 PRPF40A

2.29e-06188906d62cc37e86b7b186e53aeb7f421c4e5ee28f23bd
ToppCellCOVID-19_Mild|World / Disease group, lineage and cell class

CCNH HLA-DRB5 XRN1 ANKRD11 PKN2 ANKRD12

2.99e-061979065c33454b10023decd2f5ccda9229b6512659711e
ToppCelldroplet-Mammary_Gland-nan-3m-Epithelial-basal_cell|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TRPM4 SLC66A2 KRT16 LAMA3 FAM43B SMTN

2.99e-0619790687d09f53b84af482116d3e2076eab1a9e555a2a6
ToppCelldroplet-Mammary_Gland-nan-3m-Epithelial-basal_cell|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TRPM4 SLC66A2 KRT16 LAMA3 FAM43B SMTN

2.99e-061979065bf5187fcba4ccc3f83bc9e884e40ff344a3d109
ToppCellPBMC-Mild|PBMC / Location, Disease Group, Cell group, Cell class (2021.03.09)

CCNH HLA-DRB5 XRN1 ANKRD11 PKN2 ANKRD12

3.08e-0619890644417089b62056269cac38d3134ff209c05b7007
ToppCellPBMC-Mild|PBMC / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

CCNH HLA-DRB5 XRN1 ANKRD11 PKN2 ANKRD12

3.08e-0619890628ef3fc4c17dcb765537b75917f7db78baa522db
ToppCell(03)_KRT6B+-(2)_GFP_FOXI1|(03)_KRT6B+ / shred by cell type by condition

SMC3 BRD4 SYNE2 ANKRD11 IRS1 ANKRD12

3.17e-06199906c425e7975f492ed5cfcca022248adb627e1d27d4
ToppCell(01)_IL1RL1+-(2)_GFP_FOXI1|(01)_IL1RL1+ / shred by cell type by condition

SMC3 BRD4 SYNE2 ANKRD11 ANKRD26 ANKRD12

3.17e-06199906a2f7d0cabf35b80fe239fae34a77bf9344d5d743
ToppCellLPS_anti-TNF-Mesenchymal_myocytic|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

MYH10 DDR2 ZFHX3 IRS1 ADCY5 SMTN

3.27e-0620090667dcbd86fbc79fd585d0793f979e4aac100326c9
ToppCellLPS_only-Mesenchymal_myocytic|LPS_only / Treatment groups by lineage, cell group, cell type

MYH10 DDR2 ZFHX3 IRS1 ADCY5 SMTN

3.27e-062009068bc9923f82bfb836e2f524204c92050edeae8ca5
ToppCellAdult-Mesenchymal-airway_smooth_muscle_cell-D122|Adult / Lineage, Cell type, age group and donor

MYH10 SACS PPFIA2 ADCY5 SMTN

1.90e-0516190564891f6f2ee1693c8481e951b9346e2f92d602e3
ToppCellRV-13._Vascular_Smooth_Muscle|RV / Chamber and Cluster_Paper

MYH10 EPPK1 PPFIA2 LAMA3 ZFHX3

1.90e-0516190547b3b7662cbb671ccc086dc0a0cabd65f63eb5a1
ToppCellwk_20-22-Mesenchymal-Myofibro_&_SMC-Early_airway_SMC_1|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

DLGAP2 ZMAT5 MLH3 ANKRD26 ZFHX3

2.33e-0516890553a982869dbf14f6a948589be9f2f3df3b9a7e97
ToppCellfacs-Large_Intestine-Proximal-3m-Epithelial|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TRPM4 HOXB7 SYNE2 KBTBD11 NLRP6

2.68e-05173905e1378201b15ffb98e196ac39fe3ee4b4078953bd
ToppCellAdult-Mesenchymal-airway_smooth_muscle_cell|Adult / Lineage, Cell type, age group and donor

MYH10 SACS PPFIA2 ADCY5 SMTN

2.68e-05173905a5331721bd9f9a66530dd4ffe28cb3a5a8cad8fc
ToppCellfacs-Large_Intestine-Proximal-3m|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TRPM4 HOXB7 SYNE2 KBTBD11 NLRP6

2.68e-0517390599532bb768ee35fed939a377acb5215d3f8904bd
ToppCellfacs-Large_Intestine-Proximal-18m-Epithelial|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HOXB7 LRFN3 SERF2 KBTBD11 GADD45GIP1

2.91e-05176905d1c4c78a6d4a4ad37912eade4b7d16ef84b9a706
ToppCellfacs-Large_Intestine-Proximal-3m-Epithelial-nan|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TRPM4 HOXB7 CAPN1 KBTBD11 NLRP6

2.91e-051769051dd54bfaa58541de51e5a8328651d390833bd480
ToppCellfacs-Large_Intestine-Proximal-18m|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HOXB7 LRFN3 SERF2 KBTBD11 GADD45GIP1

2.91e-051769058c2f830124b3bd7c3a483aabe060a1d202c4a409
ToppCellRA-13._Vascular_Smooth_Muscle|RA / Chamber and Cluster_Paper

MYH10 PPFIA2 LAMA3 ADCY5 ITPR1

3.50e-05183905818fd886e0188091310825f9145fa53328f2c979
ToppCelldroplet-Bladder-nan|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SYNE2 ANKRD11 PKN2 ANKRD12 PRPF40A

3.88e-05187905663991a8afe652e92363b64bcbd68c14d0307f0e
ToppCell10x5'-GI_small-bowel-Lymphocytic_T_CD4-T_CD4/CD8|GI_small-bowel / Manually curated celltypes from each tissue

SYNE2 ANKRD11 ANKRD12 ARIH1 ITPR1

3.98e-05188905ab9b725d6e0cdab8e9ddda6dee09e14730e9a578
ToppCellLA-13._Vascular_Smooth_Muscle|LA / Chamber and Cluster_Paper

MYH10 PPFIA2 LAMA3 ITPR1 SMTN

3.98e-0518890534e1b074a3995aa46ab194eb45115d76d1a5514d
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

MYH10 TRPM3 KRT19 NPAS3 ABTB2

4.08e-05189905fc88c51ace7d883c01617f3f9b5fab70cc91cc09
ToppCellLA-13._Vascular_Smooth_Muscle|World / Chamber and Cluster_Paper

MYH10 PPFIA2 LAMA3 ITPR1 SMTN

4.08e-051899056b3e88751b95fc2173f2c3d5061ed632d0c5f01c
ToppCelldroplet-Large_Intestine-COLON_PROXIMAL|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CNTRL SYNE2 ANKRD11 PKN2 PRPF40A

4.29e-0519190560c986d2dcbc19d9338c03da6cb5e1d92fd48f8e
ToppCelldroplet-Large_Intestine-COLON_PROXIMAL-30m-Epithelial|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CNTRL SYNE2 ANKRD11 PKN2 PRPF40A

4.29e-0519190509db184cb90fe282a14474d7217068c58092c6f8
ToppCelldroplet-Large_Intestine-COLON_PROXIMAL-30m|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CNTRL SYNE2 ANKRD11 PKN2 PRPF40A

4.29e-05191905973117730d6ba5f127e7a0bfabfd0ff2ca7ac131
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Degenerative_Outer_Medullary_Collecting_Duct_Principal_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

MYH10 TRPM3 KRT19 NPAS3 ABTB2

4.40e-051929050bb06738e1c3ec0c044a7ee61f6cf1d4781fb53c
ToppCellNeuron-Postmitotic-Inhibitory_Neuron-SST-MGE1-4|World / Primary Cells by Cluster

SMC3 NPAS3 ANKRD12 SCGN NPAS1

4.51e-051939052eb6e4cff4fe3ce564c1581f6f7df4834895aaa9
ToppCell5'-Adult-SmallIntestine-Endothelial-lymphatic_endothelial-LEC3_(ADGRG3+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

DLGAP2 MYH10 AMOT KBTBD11 SMTN

4.51e-05193905bd0027fa97de41ae22ff64a61c8e217496f122ca
ToppCelldroplet-Mammary_Gland-nan-21m-Epithelial-basal_cell|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TRPM4 SLC66A2 EPPK1 LAMA3 SMTN

4.74e-05195905717e6a66bad50e711442d71360b540789646b334
ToppCelldroplet-Mammary_Gland-nan-21m-Epithelial-basal_cell|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TRPM4 SLC66A2 EPPK1 LAMA3 SMTN

4.74e-0519590510774b5ce17d4edd23dbf4709b11cc87cc2b87be
ToppCelltumor_Lung-T/NK_cells-Exhausted_Tfh|T/NK_cells / Location, Cell class and cell subclass

KRT19 HLA-DRB5 SERF2 ANKRD12 ITPR1

4.85e-051969055a0b5aeff7e535781ea2a4c85799bb468afcb6f8
ToppCelldroplet-Mammary_Gland-nan-21m-Epithelial|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TRPM4 SLC66A2 EPPK1 LAMA3 SMTN

4.97e-05197905f4dad4423384a2a25e064c849ffccf2811573be0
ToppCell3'-Broncho-tracheal-Epithelial-Airway_epithelium-respiratory_basal_cell-Suprabasal-Suprabasal_L.0.0.2.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

EPPK1 KRT16 KRT19 CAPN1 LAMA3

4.97e-051979052430f31d9312338e0ca23bfc6bdb0365340860fd
ToppCellH1299-infected-SARSCoV2|infected / Cell line, Condition and Strain

CWF19L2 SERF2 ANKRD26 ANKRD12 PRPF40A

4.97e-051979050fa3e4cf93e77d78b1f97b906c5b13ca741ae17e
ToppCell(02)_MMP9/10+-(2)_GFP_FOXI1|(02)_MMP9/10+ / shred by cell type by condition

BRD4 SYNE2 ANKRD11 IRS1 ANKRD12

5.22e-0519990518a7f9ced4364f45b184bd529f32ef02c27779d3
ToppCell3'-Broncho-tracheal-Epithelial-Airway_epithelium-respiratory_basal_cell-Suprabasal-Suprabasal_L.0.0.2.2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

KRT16 KRT19 CAPN1 SREBF1 LAMA3

5.22e-05199905c88a28a73f54dc571f2ff1e4b55073f83cbead2c
ToppCellTracheal-10x5prime-Stromal-Myofibroblastic-Muscle_smooth_systemic_arterial|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

PPFIA2 SPTB ZFHX3 ADCY5 SMTN

5.22e-05199905c2903b1a4b91e94bbdaa909bacefe901255cf248
ToppCellLPS_IL1RA_TNF-Mesenchymal_myocytic|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

ZFHX3 IRS1 ADCY5 ITPR1 SMTN

5.34e-05200905f599e4b051ac3dad11ad437e98dc8ea6754cca53
ToppCellBronchial-NucSeq-Stromal-Myofibroblastic|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

MYH10 SACS PPFIA2 ADCY5 SMTN

5.34e-05200905a66449b22b39dd6987fc2c3ed160d24564234ced
ToppCellmild|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

SYNE2 XRN1 ANKRD11 PKN2 ANKRD12

5.34e-0520090512f1685ce8f218433068e090c9d839cd5a1910bf
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW16-Neuronal-Intermediate|GW16 / Sample Type, Dataset, Time_group, and Cell type.

HABP4 XIRP2 KRT19 SPTB SIM1

5.34e-05200905a3fcd901cb281920f1bafdfd676399a6dc37355e
ToppCellCOVID-19-COVID-19_Mild|COVID-19 / Disease, condition lineage and cell class

CCNH HLA-DRB5 ANKRD11 PKN2 ANKRD12

5.34e-0520090562c25042086f1afd1102e0720e933c2e476468fd
ToppCellLPS_IL1RA-Mesenchymal_myocytic|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

ZFHX3 IRS1 ADCY5 ITPR1 SMTN

5.34e-0520090577631c471cc5d453a749784f838cfa6408caf09b
ToppCellfrontal_cortex-Neuronal-GABAergic_neuron-Sncg-Sncg_Vip_Itih5|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

NPAS3 SCGN ABTB2 NPAS1

8.44e-051149049f0c8dfd740d50448a6c91a00e7bae4dfc9b3302
ToppCellILEUM-non-inflamed-(3)_MNP-(3)_moDC|(3)_MNP / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

CCNH ATXN2 ANKRD11 ANKRD12

1.62e-04135904b7a792a7c0c22d8b703509f134115f0e394d7de0
ToppCell(08)_Brush+PNEC-(2)_GFP_FOXI1|(08)_Brush+PNEC / shred by cell type by condition

BRD4 SYNE2 ANKRD11 ANKRD12

1.76e-04138904817e3f639604ea95adae01e8685ffaa2e0aff7a8
ToppCellControl-Epithelial_alveolar-AT_1-AT2_Progenitor|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

XIRP2 KRT19 LAMA3 MAGEF1

1.97e-0414290494e277f038f4006d99ff50222b0f5cf89bc3d46d
ToppCellLPS-antiTNF-Myeloid-Myeloid_granulocytic|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DLGAP2 XIRP2 ZMYM5 STRIP1

2.02e-041439044a0f26eef935fe68a1da5d319503059a8a8682dd
ToppCellLPS-antiTNF-Myeloid-Myeloid_granulocytic-Neutrophils|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DLGAP2 XIRP2 ZMYM5 STRIP1

2.02e-0414390465328a0a2f3972fac596e07933e74b2ef7cceb84
ToppCellThalamus-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)|Thalamus / BrainAtlas - Mouse McCarroll V32

DLGAP2 ECEL1 SIM1 NPAS1

2.31e-04148904afebb64365c94b9476494bffe7c364677f19c8cf
ToppCellAdult-Mesenchymal-chondrocyte-D122|Adult / Lineage, Cell type, age group and donor

MYH10 TRPM3 PPFIA2 NCKIPSD

2.31e-0414890481a1e6fdd942a612bf523c59b8b4974f6ca1fdce
ToppCellThalamus-Neuronal-Inhibitory|Thalamus / BrainAtlas - Mouse McCarroll V32

DLGAP2 ECEL1 SIM1 NPAS1

2.31e-041489045f82e5ecacfd223020b8ee975c17d68c1fe6db38
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Cortical_Collecting_Duct_Principal_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

TRPM3 PPFIA2 NPAS3 ABTB2

2.49e-04151904f4f7156b2c0cfc78fd1841e07c9915d97ced561f
ToppCellmild_COVID-19_(asymptomatic)-MAIT|mild_COVID-19_(asymptomatic) / disease group, cell group and cell class (v2)

CCNH TRPM3 DDR2 TLN2

2.62e-0415390426852f3d8f80e102e24bcb90e24aac26fdc9a32c
ToppCellLPS-antiTNF-Stromal_mesenchymal-Myocytic|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PPFIA2 ZFHX3 ADCY5 SMTN

2.82e-041569046365b69ede98bc866e996bc52736b00401aacf6f
ToppCell10x5'-bone_marrow-Lymphocytic_T_CD4-T_CD4/CD8|bone_marrow / Manually curated celltypes from each tissue

CCNH SYNE2 ANKRD12 ARIH1

2.82e-041569041545169694f686d28648a68b552c2ae606599d66
ToppCellfrontal_cortex-Neuronal-GABAergic_neuron-Vip-Vip_Crispld2_Kcne4|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

NPAS3 LAMA3 ABTB2 NPAS1

2.82e-04156904896e2d958be0a5c62fb6eebad2dfb7e1ce69f3ad
ToppCellLPS-IL1RA+antiTNF-Stromal_mesenchymal-Fibroblasts|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CNTRL ECEL1 ABTB2 ITPR1

2.89e-04157904f086753b51860e23f1275bd75e8802d2a7d7b70a
ToppCellwk_15-18-Epithelial-Proximal_epithelial-basal_intermediate_|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

KRT16 KRT19 LAMA3 SIX2

2.96e-0415890498712ed7e8e65e8c5ff9318cf0e0a04e271a055d
ToppCellfacs-Lung-Endomucin-24m-Lymphocytic-mature_NK_T_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PPFIA2 ANKRD28 TLN2 LIN9

3.03e-041599044000ed0d3b7d488722bcd0042fa2ff4405aaab82
ToppCellfacs-Lung-Endomucin-24m-Lymphocytic-Natural_Killer_T_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PPFIA2 ANKRD28 TLN2 LIN9

3.03e-041599047619d0d49738dd08daf01b42664691a5323aa793
ToppCellTCGA-Liver-Primary_Tumor-Hepatocellular_Carcinoma-Hepatocellular_Carcinoma-7|TCGA-Liver / Sample_Type by Project: Shred V9

HABP4 TRPM3 LAMA3 IRS1

3.03e-0415990470288df54adab167c0f50675128619299077db11
ToppCellRV-13._Vascular_Smooth_Muscle|World / Chamber and Cluster_Paper

EPPK1 PPFIA2 LAMA3 ZFHX3

3.10e-0416090429c9b4770d0e73d59cffc7937b179484c76b6dcc
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Cortical_Collecting_Duct_Principal_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

MYH10 MAPK15 TRPM3 KRT19

3.10e-041609047064af50fc10e3ea03badf415306222b74db0f95
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Vip-Vip_Crispld2_Kcne4|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

NPAS3 LAMA3 ABTB2 NPAS1

3.18e-04161904be77e99faf653480c166305df3a4e93db76f0dcb
ToppCell10x5'v1-week_12-13-Hematopoietic-HSC/MPP_and_pro-HSC/MPP|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

DLGAP2 XIRP2 NPAS3 C1orf74

3.18e-0416190446b5d80d2d521fb69752aba4c10383e715a32002
ToppCellLPS-IL1RA-Epithelial_alveolar-AT_1-AT1|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

KRT16 TRPM3 KRT19 LAMA3

3.18e-041619041e17a993126e1f2a25ee7dfbb95a74ccb2a26791
ToppCellInfluenza_Severe-gd_T|World / Disease group and Cell class

LRFN3 SYNE2 DDR2 ANO7

3.18e-04161904b3cdaed4d58d57e3c5dbc904a09388f3bf949407
ToppCellfacs-Thymus-Epithelium-3m-Epithelial-epithelial_cell_of_thymus|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EPPK1 AMOT IRS1 RBFOX2

3.25e-041629043dc39db0d5f6f3d7bcc312a6bce7aaeb914138d1
ToppCellfacs-Thymus-Epithelium-3m-Epithelial|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EPPK1 AMOT IRS1 RBFOX2

3.25e-041629040a7138266054ea5954649c8b61ef93905d56b068
ToppCellfacs-Thymus-Epithelium-3m-Epithelial-TECs|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EPPK1 AMOT IRS1 RBFOX2

3.25e-0416290425323785dd33337bcefd05958a4a1a208a9ceb04
ToppCellBasal_cells-IPF_04|World / lung cells shred on cell class, cell subclass, sample id

EPPK1 KRT16 AMOT SIX2

3.33e-04163904679e25e5548d157d49a73057a3b5617dccda260f
ToppCellSevere-Lymphoid-NK-CCR7+_T|Severe / Condition, Lineage, Cell class and cell subclass

DHX40 SPTB SYNE2 C1orf74

3.33e-041639048f0d8c124f1569a5a6bc1db7581989f24d63cca3
ToppCellFetal_brain-fetalBrain_Zhong_nature-GW16-Neuronal-GABAergic_neurons|GW16 / Sample Type, Dataset, Time_group, and Cell type.

NPAS3 ANKRD12 SCGN NPAS1

3.41e-041649044d7b2d0980fb4f47721fa2891151e2bd892ccb91
ToppCellfacs-Pancreas-Exocrine-24m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MAPK15 TRPM3 CEP83 NPAS3

3.41e-04164904b895674ed2df87db8fbfb30b7e31620945588491
ToppCelldroplet-Lung-21m-Hematologic-myeloid-classical_monocyte-classical_monocyte_l15|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SPTB NCKIPSD CEP83 ANKRD26

3.49e-0416590494a5211072464fc24592bb107a853ce832e816fe
ToppCellBAL-Mild-Myeloid-MoAM-MoAM5-|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

EPPK1 KRT16 ANO7 TLN2

3.57e-04166904006ced12f69ef13ddcba5a3891ddc7c18c384863
ToppCellBAL-Mild-Myeloid-MoAM-MoAM5|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

EPPK1 KRT16 ANO7 TLN2

3.57e-04166904ac28c8cac1e94be0c47fb862c5809c92cdaa11f3
ToppCellBAL-Mild-Myeloid-MoAM-MoAM5-|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

EPPK1 KRT16 ANO7 TLN2

3.57e-041669046bb3410e65c971acc458c472015afcec6de6e310
ToppCellfacs-Lung-24m-Hematologic-lymphocytic-mature_NK_T_cell-mature_NK_T_cell_l22|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

PPFIA2 ANKRD28 TLN2 LIN9

3.57e-04166904bcdaab49bde5beba750b76fdcc3781a3c12c4fff
ToppCellNS-critical-d_0-4-Epithelial-unknown_epithelial|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

EPPK1 LRFN3 RBFOX2 SMTN

3.57e-04166904dd02bbe4af609c6348dc92417254f4740f2900a8
ToppCellfacs-Lung-24m-Hematologic-lymphocytic-mature_NK_T_cell|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

PPFIA2 ANKRD28 TLN2 LIN9

3.57e-041669045e3b998d740b24f790fad37350d704ca0ea10b77
ToppCellBAL-Mild-Myeloid-MoAM-MoAM5|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)

EPPK1 KRT16 ANO7 TLN2

3.57e-04166904823ec03714884cb860a1260410feac8c536b6d06
ToppCellAdult-Mesenchymal-vascular_smooth_muscle_cell-D175|Adult / Lineage, Cell type, age group and donor

MYH10 SPTB TLN2 ADCY5

3.65e-04167904c4e321bb87512ea839f324c92c0f1afea891483f
ToppCellFrontal_cortex-Neuronal-Excitatory-eN2(Slc17a7_Slc17a6)-Syt6-Excitatory_Neuron.Slc17a7.Syt6-Bdnf_(Deep_layer_pyramidal_cells)-|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

KRT26 XIRP2 SCGN

3.69e-046990324a480394630385ee51b1dfe1123480107a11403
ToppCellFrontal_cortex-Neuronal-Excitatory-eN2(Slc17a7_Slc17a6)-Syt6-Excitatory_Neuron.Slc17a7.Syt6-Bdnf_(Deep_layer_pyramidal_cells)|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

KRT26 XIRP2 SCGN

3.69e-04699031ab1d92e03a31bb1fe87f055d407a81c4d1d81b8
DrugFlecainide acetate [54143-56-5]; Down 200; 8.4uM; MCF7; HT_HG-U133A

HABP4 EPPK1 BRD4 CAPN1 TLN2 ABTB2 ZMYM5 RBFOX2

1.20e-061989083418_DN
DrugOxprenolol hydrochloride [6452-73-9]; Down 200; 13.2uM; MCF7; HT_HG-U133A

TRPM4 DCAF8 BRD4 SREBF1 ANKRD26 ZFHX3 SMTN

1.24e-051959077225_DN
Drug5211181; Down 200; 12uM; MCF7; HT_HG-U133A_EA

TRPM4 EPPK1 DCAF8 CNTRL NCKIPSD ANKRD26 TOGARAM1

1.37e-05198907950_DN
Drugmagnesium ammonium phosphate

GPI KRT16

1.55e-052902CID000178727
Drugcannon

MLH3 KRT16 CAPZB NPAS3 ZFHX3

2.08e-0584905CID003050747
Diseaseplatelet component distribution width

HABP4 TRPM3 ATXN2 ANKRD28 PKN2 IRS1 SIN3A PLEC SCGN LIN9 ADCY5

1.37e-057558711EFO_0007984
Diseasesphingomyelin 14:0 measurement

TRPM3 SYNE2 ZFHX3

1.63e-0517873EFO_0010390
Diseaseresting heart rate

HABP4 EPPK1 PPFIA2 SREBF1 PLEC

8.13e-05149875EFO_0004351
DiseaseCongenital muscular hypertrophy-cerebral syndrome

SMC3 BRD4

8.54e-055872C1802395
DiseaseCornelia de Lange Syndrome 3

SMC3 BRD4

8.54e-055872C1853099
DiseaseCornelia de Lange Syndrome 1

SMC3 BRD4

8.54e-055872C4551851
Diseaselymphocyte count

HABP4 ZMAT5 EPPK1 ATXN2 SPEF2 SPTB HLA-DRB5 SREBF1 ANKRD11 PKN2 PLEC FAM43B ADCY5 ITPR1

9.30e-0514648714EFO_0004587
Diseasecaudate nucleus volume

NPAS3 ZFHX3 LIN9

9.49e-0530873EFO_0004830
DiseaseDe Lange syndrome

SMC3 BRD4

1.28e-046872cv:C0270972
DiseaseNeurodevelopmental Disorders

SMC3 ANKRD11 ADCY5 ITPR1

1.69e-0493874C1535926
Diseasemean platelet volume

HABP4 TRPM3 ATXN2 SYNE2 ANKRD11 ANKRD28 IRS1 SIN3A PLEC LIN9 NLRP6

2.03e-0410208711EFO_0004584
Diseasecardiac arrest (biomarker_via_orthology)

TRPM4 ITPR1

2.38e-048872DOID:0060319 (biomarker_via_orthology)
Diseasecleft palate (implicated_via_orthology)

CAPZB SIX2

2.38e-048872DOID:674 (implicated_via_orthology)
DiseaseCornelia De Lange Syndrome

SMC3 BRD4

2.38e-048872C0270972
DiseaseAqueductal Stenosis

MYH10 SIN3A

2.38e-048872C2936786
Diseaseobesity (implicated_via_orthology)

ANKRD26 ZFHX3 IRS1 SIM1 ITPR1

4.46e-04215875DOID:9970 (implicated_via_orthology)
Diseasecalcium measurement

ATG16L1 SYNE2 SREBF1 ZFHX3 PLEC PKN3 ZMYM5 ITPR1

5.38e-04628878EFO_0004838
Diseaseautosomal dominant cerebellar ataxia (implicated_via_orthology)

ATXN2 ITPR1

5.56e-0412872DOID:1441 (implicated_via_orthology)
DiseaseAnemia, Hemolytic, Acquired

GPI SPTB

6.56e-0413872C0002879
DiseaseAnemia, Hemolytic

GPI SPTB

6.56e-0413872C0002878
DiseaseAnemia, Microangiopathic

GPI SPTB

6.56e-0413872C0002889
DiseaseMicroangiopathic hemolytic anemia

GPI SPTB

6.56e-0413872C0221021
Diseasethyroid gland papillary carcinoma (is_marker_for)

RAP1GAP BRD4

7.64e-0414872DOID:3969 (is_marker_for)
Diseasefourth ventricle volume measurement

CWF19L2 XIRP2

1.00e-0316872EFO_0010303
Diseasesusceptibility to strep throat measurement

ATG16L1 LAMA3 MAGEF1

1.49e-0376873EFO_0008408
Diseaseheart failure, diabetes mellitus, stroke, atrial fibrillation, mortality, coronary artery disease, cancer

ANKRD26 ZFHX3

1.58e-0320872EFO_0000275, EFO_0000400, EFO_0000712, EFO_0001645, EFO_0003144, EFO_0004352, MONDO_0004992
Diseasemyeloid white cell count

ATXN2 HLA-DRB5 SREBF1 TLN2 ZFHX3 PKN2 LIN9 ADCY5 PKN3

1.77e-03937879EFO_0007988
Diseaseblood phosphate measurement

ATG16L1 RAP1GAP ATXN2 ZFHX3

1.78e-03174874EFO_0010972
Diseaseurate measurement, bone density

DLGAP2 PPFIA2 CEP83 ANKRD11 NPAS3 SIM1 ITPR1

2.37e-03619877EFO_0003923, EFO_0004531
Diseasemean fractional anisotropy measurement

EPPK1 ANKRD11 PLEC

2.82e-0395873EFO_0008399

Protein segments in the cluster

PeptideGeneStartEntry
FDFAREKDQRSLDIN

DCUN1D4

201

Q92564
DFNRDLRERLETANK

AMOT

506

Q4VCS5
EAERFSRKAAQAARD

CNTRL

1021

Q7Z7A1
SRKAAQAARDLTRAE

CNTRL

1026

Q7Z7A1
EEQLARLRADANRKF

CCNH

16

P51946
QGDENKSVRDRFNAR

ANKRD11

2571

Q6UB99
SDSFEQFRRAAREKE

BRD4

1221

O60885
EANRLNAENEKDSRR

ATG16L1

201

Q676U5
SRGANINAFDKKDRR

ANKRD28

161

O15084
DLRTRFRTQNDFADL

C1orf74

241

Q96LT6
KRAASFRQNSASERA

DLGAP2

1026

Q9P1A6
RNFRSQAEKAQLEAE

CEP83

511

Q9Y592
KDVAAHFLARERRND

ADCY5

1046

O95622
DDSKTSVRDRFNARQ

ANKRD12

1971

Q6UB98
SKRELELAFQRARDE

ANKRD26

1026

Q9UPS8
KRDFFLANASRARSE

CAPN1

461

P07384
ARLRKLEVEANNAFD

CAPZB

91

P47756
TFENSADADRAREKL

RBFOX2

166

O43251
RNAARSRRGKENLEF

NPAS1

51

Q99742
QNDNARLTADDFRLK

KRT26

161

Q7Z3Y9
DAKAARDAQERSRAA

ARIH1

396

Q9Y4X5
KLDRQQDSAARDRTD

ANO7

121

Q6IWH7
DNARLAADDFRTKFE

KRT19

156

P08727
RNSKRSRLFSDEDDR

LIN9

56

Q5TKA1
ALADEADRARAKARA

MAGEF1

276

Q9HAY2
NSQKDFLEDRRAAVD

HLA-DRB5

91

Q30154
RNRNFGKHLREAEAD

LAMA3

1981

Q16787
DQDASRSRLRNAQEK

ITPR1

336

Q14643
RADANKNARNDFLKE

DDR2

611

Q16832
DAFRDKTDAQRTFRE

MAPK15

46

Q8TD08
SEEFLKREARANQLA

ATXN2

431

Q99700
AFSDFKRLQRQSDAR

FAM43B

201

Q6ZT52
RDANSFKSRDQRGVQ

FANCM

1196

Q8IYD8
QQLQRKRRDEAAAAA

HABP4

51

Q5JVS0
RDSEATRKNTNDAFL

MLH3

426

Q9UHC1
RNARAEVLRQAKANF

CWF19L2

26

Q2TBE0
KRANRDQDSSDDERA

DCAF8

121

Q5TAQ9
QIDNARLAADDFRTK

KRT16

191

P08779
RSELNLRRLFDANKD

GPI

21

P06744
SLDRRAAELRLADNF

LRFN3

56

Q9BTN0
AASAADLDNRFRKRT

IRS1

511

P35568
ERKAFARAARFLAAN

ECEL1

101

O95672
FNSLLEKAEARERER

PRPF40A

721

O75400
KEQRDSDLAAESNFR

HOXB7

111

P09629
QAARRKRELARAQDD

GCFC2

141

P16383
DRRNRKFKEAERLFS

MEAF6

76

Q9HAF1
AQADKERRARLQAEA

GADD45GIP1

146

Q8TAE8
RRNDDKSISDARARF

DHX40

746

Q8IX18
FDRNKDGRLDLNDLA

SCGN

161

O76038
RLEKQAFLDQNADRA

SACS

4361

Q9NZJ4
ANASRRKLQRELDDA

MYH10

1896

P35580
KRADARDVAAQLQER

NLRP6

86

P59044
RRLDESDDKNFRRGS

PPFIA2

1181

O75334
ADEKRALASFNQEER

NKAP

376

Q8N5F7
ALASFNQEERRKREN

NKAP

381

Q8N5F7
SRRTQDRKALAEAQA

PKN3

206

Q6P5Z2
RAKSRRNLDFQDVLD

RTCB

436

Q9Y3I0
RRLKDFQDALDREAA

SPEF2

376

Q9C093
FQDTNARSLAERKRE

UVSSA

146

Q2YD98
EKSRQLRDAQQDARD

SMC3

251

Q9UQE7
RSNKDNLREAFRIAE

SYNE2

236

Q8WXH0
AAAAARRQEQTLRDA

EPPK1

4761

P58107
RAETAAQRAEALKDF

RAP1GAP

551

P47736
GKAREFNRNQRKDSE

STRIP1

46

Q5VSL9
RRDDGLSAAARKQRD

SERF2

26

P84101
KNAARTRREKENSEF

SIM1

6

P81133
FKNRRQRDRAAAAKN

SIX6

176

O95475
SRLSAEEQAKFRLDN

SIN3A

641

Q96ST3
SRDAARSRRGKENFE

NPAS3

56

Q8IXF0
RKALSEAQARFNESS

PKN2

251

Q16513
SAAKRQRLNELRDAA

KBTBD11

241

O94819
FADLARRKDDAQQRS

NCKIPSD

386

Q9NZQ3
RKQADLDLARGDFAQ

SREBF1

586

P36956
RLDARAATEKFNQDL

ABTB2

476

Q8N961
TEARARAKAERENAD

ATAD3B

191

Q5T9A4
DREQNNDALEKSLRR

XIRP2

1856

A4UGR9
SAADKAEEFRRQQAD

XPNPEP1

361

Q9NQW7
KDDRFNSSNDERIRV

TRPM3

1231

Q9HCF6
RSLALADDAAFRERA

PTH2

61

Q96A98
ADDAAFRERARLLAA

PTH2

66

Q96A98
QQRGRRFRSAKEAED

XRN1

96

Q8IZH2
DNDNSSARLFERSRI

SPTB

31

P11277
QAKARQAEAAERSRL

PLEC

1571

Q15149
RAQARAEEDAQRFRK

PLEC

2531

Q15149
RQRDRAAEAKERENN

SIX2

176

Q9NPC8
LTASENRKRNAFREE

ZMYM5

426

Q9UJ78
ARERQQKLLAEFASR

UBR3

1186

Q6ZT12
FRDAAAILLDEQNKR

ZMAT5

41

Q9UDW3
DFSEDNRNKCRIATA

TLN2

1551

Q9Y4G6
RASDNLVRAAQKAAF

TLN2

2466

Q9Y4G6
DSKRRVRQAALEAFA

TOGARAM1

521

Q9Y4F4
ANELNARRRSFTAAD

SLC66A2

101

Q8N2U9
EEALASKRFRAERQD

SMTN

46

P53814
NFLLARARDKRESDS

TRPM4

1131

Q8TD43
RRLDFADESANKDNA

ZFHX3

586

Q15911