Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyBiologicalProcessprotein-DNA complex organization

KANSL3 TPR BPTF TAF8 ATR BRD4 LIN54 TET1 NFRKB TAF4 SRCAP NFAT5 EMSY PHF21A PHC1

8.07e-069998215GO:0071824
GeneOntologyBiologicalProcesschromatin organization

KANSL3 TPR BPTF ATR BRD4 LIN54 TET1 NFRKB SRCAP NFAT5 EMSY PHF21A PHC1

4.98e-058968213GO:0006325
GeneOntologyCellularComponentnuclear protein-containing complex

TPR ATF7 BPTF TAF8 AFF2 ATR SF3A1 BRD4 LIN54 TET1 NFRKB NUP214 TAF4 SRCAP MGA MIDEAS ATF6B STAT2 PHF21A PHC1

3.80e-0713778420GO:0140513
GeneOntologyCellularComponenttranscription regulator complex

ATF7 TAF8 LIN54 ZFHX3 TAF4 MGA MIDEAS NFAT5 ATF6B STAT2

1.37e-045968410GO:0005667
GeneOntologyCellularComponentchromatin

KANSL3 ATF7 BPTF BRD4 TET1 NFRKB ELF2 ZFHX3 TAF4 SRCAP MGA NFAT5 ATF6B CIC STAT2 PHC1

2.37e-0414808416GO:0000785
GeneOntologyCellularComponenthistone deacetylase complex

TET1 SRCAP MIDEAS PHF21A

3.83e-0485844GO:0000118
GeneOntologyCellularComponentGABA-ergic synapse

GABRR1 CACNA1E ATR L1CAM BSN

5.24e-04164845GO:0098982
HumanPhenoClinodactyly of the 5th finger

TPR BPTF HSPG2 AFF2 ATR BRD4 TRAIP L1CAM TAF4 SRCAP MBD5 PHF21A

1.22e-054203512HP:0004209
HumanPhenoClinodactyly of hands

TPR BPTF HSPG2 AFF2 ATR BRD4 TRAIP L1CAM TAF4 SRCAP MBD5 PHF21A

1.25e-054213512HP:0001157
HumanPhenoDeviation of the 5th finger

TPR BPTF HSPG2 AFF2 ATR BRD4 TRAIP L1CAM TAF4 SRCAP MBD5 PHF21A

1.25e-054213512HP:0009179
HumanPhenoRadial deviation of finger

TPR BPTF HSPG2 AFF2 ATR BRD4 TRAIP L1CAM TAF4 SRCAP MBD5 PHF21A

2.36e-054483512HP:0009466
HumanPhenoFinger clinodactyly

TPR BPTF HSPG2 AFF2 ATR BRD4 TRAIP L1CAM TAF4 SRCAP MBD5 PHF21A

2.58e-054523512HP:0040019
HumanPhenoRadial deviation of the hand or of fingers of the hand

TPR BPTF HSPG2 AFF2 ATR BRD4 TRAIP L1CAM TAF4 SRCAP MBD5 PHF21A

2.82e-054563512HP:0009485
HumanPhenoDeviation of finger

TPR BPTF HSPG2 LONP1 AFF2 ATR BRD4 TRAIP L1CAM TAF4 SRCAP MBD5 PHF21A

2.84e-055373513HP:0004097
HumanPhenoRecurrent hand flapping

AFF2 TAF4 MBD5 CIC

4.51e-0530354HP:0100023
HumanPhenoDeviation of the hand or of fingers of the hand

TPR BPTF HSPG2 LONP1 AFF2 ATR BRD4 TRAIP L1CAM TAF4 SRCAP MBD5 PHF21A

4.80e-055643513HP:0009484
HumanPhenoAbnormal 5th finger morphology

TPR BPTF HSPG2 AFF2 ATR BRD4 TRAIP L1CAM TAF4 SRCAP MBD5 PHF21A

8.44e-055093512HP:0004207
HumanPhenoElbow dislocation

HSPG2 ATR BRD4 L1CAM SRCAP

2.38e-0484355HP:0003042
HumanPhenoClinodactyly

TPR BPTF HSPG2 AFF2 ATR BRD4 TRAIP L1CAM TAF4 SRCAP MBD5 PHF21A

2.70e-045743512HP:0030084
MousePhenooptic neuropathy

TDRD7 ELP1

2.47e-052702MP:0006222
DomainLon_bac/euk-typ

LONP1 LONP2

1.72e-052782IPR004815
DomainPept_S16_C

LONP1 LONP2

1.72e-052782IPR008269
DomainPeptidase_S16_AS

LONP1 LONP2

1.72e-052782IPR008268
DomainLon_Prtase

LONP1 LONP2

1.72e-052782IPR027065
DomainLON_PROTEOLYTIC

LONP1 LONP2

1.72e-052782PS51786
DomainLon_C

LONP1 LONP2

1.72e-052782PF05362
DomainLON_SER

LONP1 LONP2

1.72e-052782PS01046
DomainLON

LONP1 LONP2

2.55e-046782SM00464
DomainLON_N

LONP1 LONP2

2.55e-046782PS51787
DomainLON_substr-bd_dom

LONP1 LONP2

2.55e-046782IPR003111
DomainLON_substr_bdg

LONP1 LONP2

2.55e-046782PF02190
DomainU-box

RBBP6 WDSUB1

4.74e-048782PF04564
DomainUbox_domain

RBBP6 WDSUB1

7.58e-0410782IPR003613
Domainp53-like_TF_DNA-bd

MGA NFAT5 STAT2

1.41e-0353783IPR008967
Domain-

BPTF RBBP6 TRAIP ZNF521 BSN WDSUB1 PHF21A

2.69e-034497873.30.40.10
DomainPUA-like_domain

LONP1 LONP2

2.81e-0319782IPR015947
DomainZnf_RING/FYVE/PHD

BPTF RBBP6 TRAIP ZNF521 BSN WDSUB1 PHF21A

3.04e-03459787IPR013083
Domain-

LONP1 LONP2

3.43e-03217823.30.230.10
DomainRibosomal_S5_D2-typ_fold_subgr

LONP1 LONP2

3.77e-0322782IPR014721
DomainBromodomain_CS

BPTF BRD4

5.24e-0326782IPR018359
PathwayREACTOME_SARS_COV_INFECTIONS

TPR HAVCR1 HSPG2 BRD4 IGKV2D-40 IGKV2D-28 NUP214 STAT2 PHF21A IGKV2-28

4.11e-054716310M39009
PathwayREACTOME_POTENTIAL_THERAPEUTICS_FOR_SARS

BRD4 IGKV2D-40 IGKV2D-28 STAT2 PHF21A IGKV2-28

6.27e-05154636M39007
Pubmed

Interaction network of human early embryonic transcription factors.

BPTF LONP1 LIN54 TET1 NFRKB ZNF521 ELF2 ZFHX3 NUP214 TAF4 MGA MIDEAS EMSY PHF21A

1.75e-13351851438297188
Pubmed

Human transcription factor protein interaction networks.

KANSL3 BPTF HSPG2 PPP2R2A LONP1 TAF8 RBBP6 LIN54 NFRKB ZNF521 ELF2 ZFHX3 NUP214 TAF4 SRCAP MGA MIDEAS CIC EMSY STAT2 PHF21A

2.35e-111429852135140242
Pubmed

Proximity-dependent Mapping of the Androgen Receptor Identifies Kruppel-like Factor 4 as a Functional Partner.

KANSL3 TAF8 BRD4 LIN54 NFRKB ELF2 MGA MIDEAS CIC EMSY PHF21A

5.97e-11268851133640491
Pubmed

H4K20me0 recognition by BRCA1-BARD1 directs homologous recombination to sister chromatids.

KANSL3 ATF7 BPTF ATR RBBP6 SF3A1 BRD4 LIN54 NFRKB ELF2 NUP214 TAF4 SRCAP MGA MIDEAS CIC EMSY PHF21A

1.89e-091294851830804502
Pubmed

Genome-wide CRISPR screens identify novel regulators of wild-type and mutant p53 stability.

KANSL3 ZC3H7A MYO9B RBBP6 LIN54 ANKRD26 ELP1 RAB11FIP5 BSN SRCAP CIC EMSY STAT2

1.96e-09588851338580884
Pubmed

SRCAP complex promotes lung cancer progression by reprograming the oncogenic transcription of Hippo-YAP/TAZ signaling pathway.

TPR BPTF RBBP6 BRD4 TET1 PHACTR4 NFRKB TAF4 SRCAP MGA MIDEAS EMSY

9.82e-09549851238280479
Pubmed

Resolution of cell fate decisions revealed by single-cell gene expression analysis from zygote to blastocyst.

ATF7 BPTF BRD4 ELF2 ZFHX3 SRCAP ZNF844 MGA NFAT5 ATF6B CIC STAT2 PHF21A PHC1

9.87e-09808851420412781
Pubmed

The Nse5/6-like SIMC1-SLF2 complex localizes SMC5/6 to viral replication centers.

TPR BPTF RBBP6 SF3A1 BRD4 LIN54 NFRKB ELF2 NUP214 TAF4 MGA PSPC1 MIDEAS CIC EMSY

1.01e-08954851536373674
Pubmed

An improved smaller biotin ligase for BioID proximity labeling.

TDRD7 LIN54 ELF2 NUP214 EMSY PHF21A PDZD2

2.29e-0812385726912792
Pubmed

The in vivo Interaction Landscape of Histones H3.1 and H3.3.

BPTF BRD4 LIN54 NFRKB ELF2 TAF4 SRCAP MGA MIDEAS CIC EMSY PHC1

3.01e-08608851236089195
Pubmed

Mapping the Ku Interactome Using Proximity-Dependent Biotin Identification in Human Cells.

TPR BPTF RBBP6 SF3A1 BRD4 ZFHX3 MGA PSPC1 EMSY

3.30e-0828385930585729
Pubmed

Large-scale characterization of HeLa cell nuclear phosphoproteins.

KANSL3 TPR BPTF ATR RBBP6 SF3A1 BRD4 PHACTR4 NFRKB ELF2 NUP214 CIC EMSY

5.03e-08774851315302935
Pubmed

Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.

TPR BRD4 LIN54 TET1 ZFHX3 NUP214 MGA CIC PHF21A PHC1

7.93e-08418851034709266
Pubmed

Hirschsprung Disease Overview – RETIRED CHAPTER, FOR HISTORICAL REFERENCE ONLY

L1CAM ELP1 BDNF EDNRB

9.90e-081885420301612
Pubmed

An Oct4-centered protein interaction network in embryonic stem cells.

KANSL3 BPTF TAF4 MGA MIDEAS EMSY PHC1

1.87e-0716785720362541
Pubmed

PRISMA and BioID disclose a motifs-based interactome of the intrinsically disordered transcription factor C/EBPα.

KANSL3 ATF7 BPTF SF3A1 BRD4 LIN54 NFRKB ELF2 TAF4 PSPC1 MIDEAS CIC EMSY PHF21A

4.48e-071103851434189442
Pubmed

Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.

BPTF PPP2R2A TAF8 DCDC1 RBBP6 TRABD BRD4 NFRKB RAB11FIP5 ZFHX3 TAF4 SRCAP MGA PHF21A

5.15e-071116851431753913
Pubmed

Proteomic analyses reveal distinct chromatin-associated and soluble transcription factor complexes.

KANSL3 TPR ATF7 BPTF MYO9B SF3A1 AP5Z1 LIN54 MGA CIC EMSY PHF21A

1.18e-06857851225609649
Pubmed

Identification of proximal SUMO-dependent interactors using SUMO-ID.

KANSL3 LIN54 NFRKB RAB11FIP5 ELF2 TAF4 MGA EMSY PHF21A

1.45e-0644485934795231
Pubmed

A direct physical interaction between Nanog and Sox2 regulates embryonic stem cell self-renewal.

BPTF TET1 MGA MIDEAS EMSY PHC1

1.64e-0614685623892456
Pubmed

Identification of the SOX2 Interactome by BioID Reveals EP300 as a Mediator of SOX2-dependent Squamous Differentiation and Lung Squamous Cell Carcinoma Growth.

BPTF LIN54 ELF2 MIDEAS CIC

1.93e-068385528794006
Pubmed

Menin and Menin-Associated Proteins Coregulate Cancer Energy Metabolism.

BPTF RBBP6 SF3A1 SRCAP PSPC1 MIDEAS EMSY STAT2

1.96e-0634185832971831
Pubmed

A human MAP kinase interactome.

TPR ZC3H7A RBBP6 NUP214 MBD5 MGA MIDEAS CIC ZNF440

3.04e-0648685920936779
Pubmed

A High-Density Map for Navigating the Human Polycomb Complexome.

KANSL3 BPTF LIN54 TET1 NFRKB MBD5 MGA PSPC1 PHC1

3.52e-0649585927705803
Pubmed

Fgf and Esrrb integrate epigenetic and transcriptional networks that regulate self-renewal of trophoblast stem cells.

KANSL3 BPTF NFRKB MGA PSPC1 PHF21A

5.00e-0617785626206133
Pubmed

Studies of the interactions between the anticytokeratin 8 monoclonal antibody TS1, its antigen and its anti-idiotypic antibody alphaTS1.

IGKV2D-28 IGKV2-28

5.90e-06285212833571
Pubmed

Two V kappa germ-line genes related to the GAT idiotypic network (Ab1 and Ab3/Ab1') account for the major subfamilies of the mouse V kappa-1 variability subgroup.

IGKV2D-28 IGKV2-28

5.90e-0628523100621
Pubmed

Hippocampal enlargement in Bassoon-mutant mice is associated with enhanced neurogenesis, reduced apoptosis, and abnormal BDNF levels.

BSN BDNF

5.90e-06285221935677
Pubmed

Structural and affinity studies of IgM polyreactive natural autoantibodies.

IGKV2D-28 IGKV2-28

5.90e-0628528993018
Pubmed

BDNF and its pro-peptide are stored in presynaptic dense core vesicles in brain neurons.

BSN BDNF

5.90e-06285222412021
Pubmed

V genes of oxazolone antibodies in 10 strains of mice.

IGKV2D-28 IGKV2-28

5.90e-0628521936125
Pubmed

Nucleotide sequences of the variable regions of a mouse monoclonal antibody MRK16.

IGKV2D-28 IGKV2-28

5.90e-0628522110659
Pubmed

Cancer-related SRCAP and TPR mutations in colon cancers.

TPR SRCAP

5.90e-06285233307343
Pubmed

[Association of single nucleotide polymorphisms of CSPG2 and HSPG2 genes with intracranial aneurysm in ethnic Han Chinese population].

HSPG2 VCAN

5.90e-06285223568740
Pubmed

Cryoglobulinemia induced by a murine IgG3 rheumatoid factor: skin vasculitis and glomerulonephritis arise from distinct pathogenic mechanisms.

IGKV2D-28 IGKV2-28

5.90e-0628522263605
Pubmed

IgM binding to injured tissue precedes complement activation during skeletal muscle ischemia-reperfusion.

IGKV2D-28 IGKV2-28

5.90e-06285215522311
Pubmed

Early induced IgM as a predictor and risk factor for severe disease outcome after West Nile virus infection.

IGKV2D-28 IGKV2-28

5.90e-06285215219549
Pubmed

Amino acid sequence of the light chain variable region from a mouse anti-digoxin hybridoma antibody.

IGKV2D-28 IGKV2-28

5.90e-0628526404298
Pubmed

Mouse olfactory ensheathing glia enhance axon outgrowth on a myelin substrate in vitro.

L1CAM BDNF

5.90e-06285219100263
Pubmed

The intracranial aneurysm susceptibility genes HSPG2 and CSPG2 are not associated with abdominal aortic aneurysm.

HSPG2 VCAN

5.90e-06285220053631
Pubmed

The functional interactome landscape of the human histone deacetylase family.

TPR PPP2R2A SF3A1 ZNF521 MIDEAS EMSY PHF21A

7.22e-0628985723752268
Pubmed

Oct4 links multiple epigenetic pathways to the pluripotency network.

TPR BPTF HSPG2 BRD4 TET1 PSPC1

1.09e-0520385622083510
Pubmed

A cohesin-RAD21 interactome.

TPR TRAIP PHACTR4 APOB PSPC1 PDZD2

1.26e-0520885622145905
Pubmed

The Tumor Suppressor CIC Directly Regulates MAPK Pathway Genes via Histone Deacetylation.

ATF7 PPP2R2A SF3A1 LIN54 ZFHX3 TAF4 MGA NFAT5 CIC

1.31e-0558385929844126
Pubmed

Quantitative interaction proteomics and genome-wide profiling of epigenetic histone marks and their readers.

BPTF TAF8 TAF4 MGA EMSY

1.39e-0512485520850016
Pubmed

Topographical variation in the distributions of versican, aggrecan and perlecan in the foetal human spine reflects their diverse functional roles in spinal development.

HSPG2 VCAN

1.77e-05385219669783
Pubmed

Haploinsufficiency of the Insulin Receptor in the Presence of a Splice-Site Mutation in Ppp2r2a Results in a Novel Digenic Mouse Model of Type 2 Diabetes.

PPP2R2A ITM2B

1.77e-05385226868295
Pubmed

BDNF: mRNA expression in urine cells of patients with chronic kidney disease and its role in kidney function.

HAVCR1 BDNF

1.77e-05385230133147
Pubmed

Pluripotency transcription factors and Tet1/2 maintain Brd4-independent stem cell identity.

BRD4 TET1

1.77e-05385229662175
Pubmed

Proteomics analysis of cardiac extracellular matrix remodeling in a porcine model of ischemia/reperfusion injury.

HSPG2 VCAN APOB NAXE

1.89e-056485422261194
Pubmed

PRC1 and PRC2 are not required for targeting of H2A.Z to developmental genes in embryonic stem cells.

MGA EMSY PHF21A PHC1

2.01e-056585422496869
Pubmed

BioID identifies novel c-MYC interacting partners in cultured cells and xenograft tumors.

KANSL3 BRD4 LIN54 NFRKB MGA

2.02e-0513485525452129
Pubmed

MYC Protein Interactome Profiling Reveals Functionally Distinct Regions that Cooperate to Drive Tumorigenesis.

BRD4 LIN54 NFRKB ELF2 MGA EMSY PHF21A

2.02e-0533985730415952
Pubmed

Nuclear actin interactome analysis links actin to KAT14 histone acetyl transferase and mRNA splicing.

TPR RBBP6 SF3A1 BRD4 PHACTR4 SRCAP PSPC1 CIC

3.43e-0550685830890647
Pubmed

B-cell extrinsic CR1/CR2 promotes natural antibody production and tolerance induction of anti-alphaGAL-producing B-1 cells.

IGKV2D-28 IGKV2-28

3.53e-05485217023586
Pubmed

A functional interaction between ATF7 and TAF12 that is modulated by TAF4.

ATF7 TAF4

3.53e-05485215735663
Pubmed

Association analysis of genes involved in the maintenance of the integrity of the extracellular matrix with intracranial aneurysms in a Japanese cohort.

HSPG2 VCAN

3.53e-05485219506372
Pubmed

Synthetic Lethal and Resistance Interactions with BET Bromodomain Inhibitors in Triple-Negative Breast Cancer.

KANSL3 TPR ATF7 BPTF PPP2R2A LONP1 ATR RBBP6 BRD4 TAF4 PSPC1

3.65e-051014851132416067
Pubmed

NANOG-dependent function of TET1 and TET2 in establishment of pluripotency.

BPTF TET1 EMSY

3.95e-052785323395962
Pubmed

Systematic analysis of the protein interaction network for the human transcription machinery reveals the identity of the 7SK capping enzyme.

TPR SF3A1 BRD4 NFRKB TAF4 SRCAP PHF21A

4.92e-0539085717643375
Pubmed

Interactome Rewiring Following Pharmacological Targeting of BET Bromodomains.

BPTF TAF8 MYO9B BRD4 NFRKB TAF4 MGA PHC1

4.94e-0553385830554943
Pubmed

NSD3-Short Is an Adaptor Protein that Couples BRD4 to the CHD8 Chromatin Remodeler.

BPTF BRD4

5.87e-05585226626481
Pubmed

The architecture of human general transcription factor TFIID core complex.

TAF8 TAF4

5.87e-05585223292512
Pubmed

The human immunoglobulin kappa locus. Characterization of the duplicated O regions.

IGKV2D-40 IGKV2-40

5.87e-0558521907917
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

KANSL3 HSPG2 MYO7A MYO9B BRD4 L1CAM ADGRB2 NUP214 SRCAP MBD5 CIC

7.89e-051105851135748872
Pubmed

Transcriptional analysis of cleft palate in TGFβ3 mutant mice.

HSPG2 VCAN L1CAM

8.71e-053585332913205
Pubmed

Bromodomain Protein BRD4 Is Essential for Hair Cell Function and Survival.

MYO7A BRD4

8.80e-05685233015071
Pubmed

Differential expression of glycosaminoglycans and proteoglycans in the migratory pathway of the primordial germ cells of the mouse.

HSPG2 VCAN

8.80e-05685212122449
Pubmed

Over-expression of the chondroitin sulphate proteoglycan versican is associated with defective neural crest migration in the Pax3 mutant mouse (splotch).

HSPG2 VCAN

8.80e-0568529486530
Pubmed

Positive and negative TAF(II) functions that suggest a dynamic TFIID structure and elicit synergy with traps in activator-induced transcription.

TAF8 TAF4

8.80e-05685211564872
Pubmed

DNA-methyltransferase1 (DNMT1) binding to CpG rich GABAergic and BDNF promoters is increased in the brain of schizophrenia and bipolar disorder patients.

TET1 BDNF

8.80e-05685225476119
Pubmed

N-Terminal Acetyltransferase Naa40p Whereabouts Put into N-Terminal Proteoform Perspective.

TPR RBBP6 SF3A1 ANKRD26 ELF2 NUP214 SRCAP CIC EMSY PHF21A

9.43e-05934851033916271
Pubmed

Defining the proximal interaction networks of Arf GTPases reveals a mechanism for the regulation of PLD1 and PI4KB.

AFF2 LIN54 PHACTR4 ANKRD26 PCDHB2 RAB11FIP5 ZFHX3 APOB MGA

1.20e-0477785935844135
Pubmed

Elongator and codon bias regulate protein levels in mammalian peripheral neurons.

VCAN ELP1

1.23e-04785229497044
Pubmed

Tails of unconventional myosins.

MYO7A MYO9B

1.23e-04785211212352
Pubmed

Canal cristae growth and fiber extension to the outer hair cells of the mouse ear require Prox1 activity.

MYO7A BDNF

1.23e-04785220186345
Pubmed

Comprehensive Characterization of Tissues Derived from Animals at Different Regenerative Stages: A Comparative Analysis between Fetal and Adult Mouse Skin.

HSPG2 VCAN

1.23e-04785237174615
Pubmed

A genome-wide association study of atopic dermatitis identifies loci with overlapping effects on asthma and psoriasis.

ATF6B EMSY

1.23e-04785223886662
Pubmed

A novel role for the peptidyl-prolyl cis-trans isomerase Cyclophilin A in DNA-repair following replication fork stalling via the MRE11-RAD50-NBS1 complex.

KANSL3 BPTF PPP2R2A RAB11FIP5 PSPC1 MIDEAS CIC

1.61e-0447285738943005
Pubmed

Dominant and redundant functions of TFIID involved in the regulation of hepatic genes.

TAF8 APOB TAF4

1.62e-044385318722179
Pubmed

Apolipoprotein B is a new target of the GDNF/RET and ET-3/EDNRB signalling pathways.

APOB EDNRB

1.64e-04885222897442
Pubmed

Nr2f1 heterozygous knockout mice recapitulate neurological phenotypes of Bosch-Boonstra-Schaaf optic atrophy syndrome and show impaired hippocampal synaptic plasticity.

HSPG2 MYO7A

1.64e-04885231600777
Pubmed

Imaging within single NPCs reveals NXF1's role in mRNA export on the cytoplasmic side of the pore.

TPR NUP214

1.64e-04885231375530
Pubmed

Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.

TPR PPP2R2A LONP1 ATR SF3A1 KIAA0586 ELP1 APOB NUP214 BSN ITM2B PSPC1

1.77e-041425851230948266
Pubmed

Interaction proteomics analysis of polycomb proteins defines distinct PRC1 complexes in mammalian cells.

TPR BPTF ANKRD26 PHC1

1.93e-0411685421282530
Pubmed

Identifying biological pathways that underlie primordial short stature using network analysis.

TPR BPTF LONP1 MYO9B SF3A1 ELP1 NUP214 SRCAP MGA PSPC1

1.99e-041024851024711643
Pubmed

Fezf1 and Fezf2 are required for olfactory development and sensory neuron identity.

L1CAM GNAL

2.10e-04985221452247
Pubmed

Retinal ganglion cell axon sorting at the optic chiasm requires dystroglycan.

HSPG2 L1CAM

2.10e-04985230149005
Pubmed

Histone demethylase KDM5C is a SAHA-sensitive central hub at the crossroads of transcriptional axes involved in multiple neurodevelopmental disorders.

L1CAM BDNF

2.10e-04985231691806
Pubmed

Widespread neuronal ectopia associated with secondary defects in cerebrocortical chondroitin sulfate proteoglycans and basal lamina in MARCKS-deficient mice.

VCAN L1CAM

2.62e-04108529184108
Pubmed

Expression of Leukaemia associated transcription factor Af9/Mllt3 in the cerebral cortex of the mouse.

AFF2 L1CAM

2.62e-041085219000783
Pubmed

Gene diversity patterns at 10 X-chromosomal loci in humans and chimpanzees.

AFF2 L1CAM

2.62e-041085212777533
Pubmed

The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.

ZC3H7A TAF8 LONP2 RBBP6 CEP83 NFRKB ZFHX3 TAF4 ITM2B PSPC1 CIC EMSY

2.78e-041497851231527615
Pubmed

Genetics of coronary artery calcification among African Americans, a meta-analysis.

CACNA1E TSBP1 SF3A1

2.86e-045285323870195
Pubmed

Tamalin is a scaffold protein that interacts with multiple neuronal proteins in distinct modes of protein-protein association.

AFF2 CEP83

3.20e-041185212586822
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

KANSL3 PPP2R2A AP5Z1 TET1 RAB11FIP5 BSN PHF21A

3.21e-0452985714621295
Pubmed

Chromatin accessibility complex subunit 1 enhances tumor growth by regulating the oncogenic transcription of YAP in breast and cervical cancer.

TPR SF3A1 BRD4

3.75e-045785338223760
Pubmed

A census of human transcription factors: function, expression and evolution.

ATF7 ELF2 ZFHX3 MGA MIDEAS NFAT5 ATF6B CIC STAT2

3.79e-0490885919274049
Pubmed

Lhx3, a LIM domain transcription factor, is regulated by Pou4f3 in the auditory but not in the vestibular system.

MYO7A BDNF

3.83e-041285217331196
Pubmed

Systematic mapping of genetic interactions for de novo fatty acid synthesis identifies C12orf49 as a regulator of lipid metabolism.

TPR ABHD14A ZC3H7A SF3A1 BRD4 NFRKB ELF2 NUP214 TAF4 MGA EMSY

3.84e-041327851132694731
InteractionNFIX interactions

KANSL3 BPTF LIN54 NFRKB ZNF521 ELF2 ZFHX3 TAF4 SRCAP MGA MIDEAS CIC EMSY

1.20e-112278513int:NFIX
InteractionELF4 interactions

KANSL3 BPTF LIN54 NFRKB ELF2 TAF4 SRCAP MGA CIC EMSY

5.38e-111158510int:ELF4
InteractionKLF3 interactions

BPTF LONP1 LIN54 NFRKB ELF2 ZFHX3 TAF4 MGA MIDEAS CIC EMSY PHF21A

2.09e-102288512int:KLF3
InteractionFEV interactions

TAF8 LIN54 NFRKB ZNF521 ZFHX3 TAF4 MGA MIDEAS CIC EMSY PHF21A

9.19e-102038511int:FEV
InteractionHNF4A interactions

KANSL3 BPTF LIN54 NFRKB ZNF521 ELF2 TAF4 SRCAP MGA MIDEAS CIC EMSY

1.78e-092758512int:HNF4A
InteractionELF1 interactions

KANSL3 BPTF LIN54 NFRKB ELF2 TAF4 SRCAP MGA EMSY

3.02e-09126859int:ELF1
InteractionNUP43 interactions

TDRD7 KANSL3 BPTF RBBP6 LIN54 NFRKB ELF2 ZFHX3 NUP214 TAF4 SRCAP MGA MIDEAS EMSY PHF21A PDZD2

6.54e-096258516int:NUP43
InteractionPAX6 interactions

BPTF LIN54 NFRKB ZNF521 ELF2 ZFHX3 APOB SRCAP MGA MIDEAS CIC PHF21A

4.30e-083668512int:PAX6
InteractionYY1 interactions

KANSL3 ATF7 BPTF BRD4 LIN54 NFRKB ELF2 TAF4 SRCAP MGA PSPC1 CIC EMSY

5.49e-084548513int:YY1
InteractionKLF8 interactions

KANSL3 BPTF PPP2R2A LIN54 NFRKB ELF2 TAF4 MGA CIC EMSY PHF21A

1.35e-073298511int:KLF8
InteractionTFCP2L1 interactions

KANSL3 BPTF BRD4 MGA MIDEAS EMSY PHC1

2.01e-0799857int:TFCP2L1
InteractionELF2 interactions

KANSL3 BPTF LIN54 NFRKB ELF2 SRCAP MGA EMSY

3.13e-07156858int:ELF2
InteractionTERF2IP interactions

KANSL3 BPTF RBBP6 BRD4 LIN54 NFRKB ELF2 TAF4 SRCAP MGA CIC EMSY PHC1

5.16e-075528513int:TERF2IP
InteractionEGR2 interactions

TET1 NFRKB ZNF521 ZFHX3 MGA MIDEAS EMSY PHF21A

6.30e-07171858int:EGR2
InteractionNFYC interactions

KANSL3 LIN54 NFRKB TAF4 MGA ATF6B CIC EMSY

8.18e-07177858int:NFYC
InteractionPOU5F1 interactions

TPR BPTF HSPG2 ATR BRD4 TET1 NFRKB ZFHX3 ITM2B MGA PSPC1 EMSY PHC1

9.72e-075848513int:POU5F1
InteractionHDAC1 interactions

TPR BPTF PPP2R2A ATR SF3A1 BRD4 TET1 ZNF521 ZFHX3 NUP214 UBASH3B MGA MIDEAS CIC EMSY STAT2 PHF21A

3.11e-0611088517int:HDAC1
InteractionAR interactions

KANSL3 TPR PPP2R2A TAF8 BRD4 LIN54 NFRKB ELF2 ZFHX3 SRCAP MGA PSPC1 MIDEAS CIC EMSY PHF21A

3.37e-069928516int:AR
InteractionMAD2L1 interactions

TPR BPTF SF3A1 BRD4 LIN54 SRCAP MGA CIC

1.12e-05252858int:MAD2L1
InteractionETS1 interactions

BPTF RBBP6 NFRKB SRCAP MGA EMSY

1.23e-05121856int:ETS1
InteractionHNF1B interactions

BPTF LIN54 NFRKB ZFHX3 MGA MIDEAS CIC

1.57e-05190857int:HNF1B
InteractionSMC5 interactions

TPR BPTF RBBP6 SF3A1 BRD4 LIN54 NFRKB ELF2 NUP214 TAF4 MGA PSPC1 MIDEAS CIC EMSY

1.69e-0510008515int:SMC5
InteractionTET1 interactions

TET1 PSPC1 BDNF PHF21A

3.85e-0545854int:TET1
InteractionH3C3 interactions

BPTF BRD4 LIN54 NFRKB ELF2 SRCAP MGA MIDEAS CIC PHC1

4.39e-054958510int:H3C3
InteractionTAF4 interactions

ATF7 TAF8 SF3A1 BRD4 TAF4 CIC

5.16e-05156856int:TAF4
InteractionL3MBTL2 interactions

KANSL3 LIN54 ELF2 MGA CIC PHF21A PHC1

5.49e-05231857int:L3MBTL2
InteractionHDAC2 interactions

KANSL3 BPTF HSPG2 PPP2R2A ATR BRD4 TET1 ZNF521 MIDEAS CIC EMSY PHF21A PHC1

6.47e-058658513int:HDAC2
InteractionTAF12 interactions

ATF7 TAF8 BRD4 ELF2 TAF4

6.52e-05100855int:TAF12
InteractionMGA interactions

KANSL3 BRD4 ELF2 MGA CIC PHF21A PHC1

6.98e-05240857int:MGA
InteractionDYNLT1 interactions

TPR HAVCR1 LIN54 KIAA0586 NFRKB ELF2 EMSY

7.16e-05241857int:DYNLT1
InteractionSNRNP40 interactions

HSPG2 RBBP6 SF3A1 BRD4 NFRKB ZFHX3 TAF4 MGA MIDEAS EMSY PHF21A

7.37e-056378511int:SNRNP40
InteractionHSPA2 interactions

TRABD SF3A1 AP5Z1 BRD4 PHACTR4 C3orf20 CIC EMSY PHC1

9.86e-05440859int:HSPA2
InteractionPHF21A interactions

TPR BRD4 TET1 ZFHX3 NUP214 MGA CIC PHF21A

1.00e-04343858int:PHF21A
InteractionTEAD1 interactions

BPTF ELF2 ZFHX3 MGA MIDEAS CIC

1.01e-04176856int:TEAD1
InteractionPHF12 interactions

BPTF ELF2 CIC EMSY PHF21A

1.02e-04110855int:PHF12
InteractionATF7 interactions

ATF7 BRD4 TAF4 CIC

1.45e-0463854int:ATF7
InteractionELK3 interactions

LIN54 TAF4 MGA CIC EMSY

1.54e-04120855int:ELK3
InteractionENO1 interactions

TDRD7 ZC3H7A ATR LONP2 TRABD SF3A1 BRD4 ZNF521 RAB11FIP5 SPINDOC C3orf20

1.71e-047018511int:ENO1
InteractionTLE3 interactions

RBBP6 BRD4 NFRKB ZFHX3 TAF4 MIDEAS CIC EMSY

1.88e-04376858int:TLE3
InteractionRAD21 interactions

TPR BRD4 TRAIP PHACTR4 APOB PSPC1 CIC PDZD2

2.17e-04384858int:RAD21
InteractionBRD3 interactions

BPTF TAF8 MYO9B RBBP6 BRD4 NFRKB RAB11FIP5 TAF4 MGA

2.35e-04494859int:BRD3
InteractionHCFC1 interactions

KANSL3 BRD4 ELP1 TAF4 MBD5 MGA CIC

2.40e-04293857int:HCFC1
InteractionMYB interactions

KANSL3 ZFHX3 MGA CIC EMSY

2.49e-04133855int:MYB
InteractionSON interactions

RBBP6 SF3A1 BRD4 PSPC1 CIC EMSY

2.50e-04208856int:SON
InteractionNFIC interactions

LONP1 BRD4 ELF2 MGA MIDEAS CIC

2.63e-04210856int:NFIC
InteractionIL17F interactions

HSPG2 BRD4 VCAN

2.99e-0431853int:IL17F
InteractionH3-3A interactions

BPTF BRD4 LIN54 NFRKB ELF2 TAF4 SRCAP MGA MIDEAS CIC EMSY

3.03e-047498511int:H3-3A
InteractionSUDS3 interactions

BPTF BRD4 TET1 ELF2 CIC

3.27e-04141855int:SUDS3
InteractionFOXK2 interactions

KANSL3 TPR BPTF BRD4 CIC EMSY

3.80e-04225856int:FOXK2
InteractionSIN3B interactions

BPTF ELF2 CIC EMSY PHF21A

3.96e-04147855int:SIN3B
InteractionKLF16 interactions

KANSL3 LIN54 NFRKB ZNF521 ELF2 TAF4 MGA EMSY

4.27e-04425858int:KLF16
InteractionTRRAP interactions

TRABD BRD4 ELF2 APOB NUP214 GNAL TAF4 SRCAP MGA PSPC1 STAT2

4.75e-047908511int:TRRAP
InteractionKANSL3 interactions

KANSL3 BRD4 ELF2 MGA

4.81e-0486854int:KANSL3
InteractionPHC1 interactions

BRD4 SRCAP MGA PHC1

4.81e-0486854int:PHC1
InteractionTAF5 interactions

TAF8 ELF2 TAF4 CIC

4.81e-0486854int:TAF5
InteractionXRCC6 interactions

TPR BPTF RBBP6 SF3A1 BRD4 LIN54 ZFHX3 MBD5 MGA PSPC1 CIC EMSY

5.02e-049288512int:XRCC6
InteractionFOXK1 interactions

AP5Z1 BRD4 RAB11FIP5 ELF2 MBD5 CIC

5.12e-04238856int:FOXK1
InteractionTAF3 interactions

TAF8 BRD4 ELF2 TAF4

5.25e-0488854int:TAF3
InteractionPML interactions

KANSL3 LONP1 ATR BRD4 LIN54 NFRKB RAB11FIP5 ELF2 TAF4 EMSY STAT2 PHF21A

5.27e-049338512int:PML
InteractionCIC interactions

ATF7 PPP2R2A SF3A1 LIN54 ZFHX3 TAF4 MGA NFAT5 CIC PHF21A

5.29e-046738510int:CIC
InteractionKDM1A interactions

TPR BRD4 LIN54 TET1 ZFHX3 NUP214 UBASH3B MGA PSPC1 CIC PHF21A PHC1

5.68e-049418512int:KDM1A
InteractionSMAD3 interactions

BPTF SF3A1 RAB11FIP5 ZFHX3 APOB NUP214 PSPC1 CIC

5.95e-04447858int:SMAD3
InteractionTAF6 interactions

PPP2R2A LONP1 TAF8 BRD4 ELF2 TAF4

5.96e-04245856int:TAF6
InteractionCDC16 interactions

LONP2 BRD4 KIAA0586 TAF4 MGA PSPC1

6.09e-04246856int:CDC16
InteractionYAP1 interactions

TPR BPTF RBBP6 SF3A1 BRD4 TET1 NFRKB TAF4 SRCAP SPINDOC MGA MIDEAS NFAT5

6.47e-0410958513int:YAP1
InteractionASF1A interactions

LIN54 NFRKB ELF2 SRCAP MGA EMSY

6.49e-04249856int:ASF1A
InteractionCEBPA interactions

KANSL3 ATF7 BPTF SF3A1 BRD4 LIN54 NFRKB ELF2 TAF4 PSPC1 MIDEAS CIC EMSY PHF21A

6.73e-0412458514int:CEBPA
InteractionKAT8 interactions

KANSL3 TPR BRD4 ELF2

7.01e-0495854int:KAT8
InteractionPRPS2 interactions

SF3A1 LIN54 NFRKB ELF2 MGA EMSY

7.05e-04253856int:PRPS2
InteractionSAP30 interactions

BPTF BRD4 TET1 UBASH3B CIC

7.07e-04167855int:SAP30
InteractionHAPSTR1 interactions

TPR PPP2R2A LONP1 RBBP6 SF3A1 RAB11FIP5 NUP214 TAF4 BSN ITM2B EMSY

7.09e-048298511int:HAPSTR1
InteractionH2BC8 interactions

BPTF BRD4 LIN54 NFRKB ELF2 SRCAP MGA MIDEAS PHC1

7.14e-04576859int:H2BC8
Cytoband2p12

IGKV2D-40 IGKV2D-28 IGKV2-40 IGKV2-28

6.92e-051178542p12
CytobandEnsembl 112 genes in cytogenetic band chr2p11

IGKV2D-40 IGKV2D-28 IGKV2-40 IGKV2-28

6.80e-04213854chr2p11
Cytoband11q13.5

MYO7A EMSY

6.95e-042185211q13.5
Cytoband19p13.1

MYO9B BRD4

3.62e-034885219p13.1
CytobandEnsembl 112 genes in cytogenetic band chr19p13

LONP1 CATSPERD MYO9B BRD4 ZNF844 ZNF440

3.68e-03797856chr19p13
GeneFamilyImmunoglobulin kappa locus at 2p11.2

IGKV2D-40 IGKV2D-28 IGKV2-40 IGKV2-28

2.26e-0483654351
ToppCell3'-Airway_Nasal-Immune_Myeloid-Myeloid_monocytic-classical_monocyte-Classical_monocytes-Classical_monocytes_L.1.2.0.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

VCAN NUP214 MSS51 MS4A6A IGSF23

1.44e-051618553a5f2877e3b29463a3a6da05009b0ab8747b4c47
ToppCell3'-Airway_Nasal-Immune_Myeloid-Myeloid_monocytic-classical_monocyte-Classical_monocytes|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MYO7A VCAN NUP214 MS4A6A IGSF23

1.87e-0517085546a81d505de845cc59f80594fce338f7fdb9250f
ToppCell3'-Airway_Nasal-Immune_Myeloid-Myeloid_monocytic-classical_monocyte|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MYO7A VCAN NUP214 MS4A6A IGSF23

1.87e-051708551a9a0487c35cf3fd5806d1f0f0e91ef0e0b9cd0a
ToppCell3'-Airway_Nasal-Immune_Myeloid-Myeloid_monocytic|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MYO7A VCAN NUP214 MS4A6A IGSF23

1.87e-05170855830646815410c47e9bca8c9bae75dfc45c9c9b33
ToppCellfacs-Lung-EPCAM-3m-Mesenchymal-pericyte_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

AFF2 TRAIP C3orf20 BDNF PDZD2

2.03e-051738553059325901b1e5e12a1a91183f14267288b2f600
ToppCelldroplet-Lung-30m-Hematologic-myeloid-plasmacytoid_dendritic_cell|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CACNA1E HAVCR1 TET1 C3orf20 PHC1

2.03e-051738554f0c065e876197ad8cae7856669f09e37ecafa3f
ToppCelldroplet-Lung-30m-Hematologic-myeloid-plasmacytoid_dendritic_cell-plasmacytoid_dendritic|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CACNA1E HAVCR1 TET1 C3orf20 PHC1

2.03e-051738559bbea566964281f47bf75d665b7d69ba8326e207
ToppCellfacs-Lung-EPCAM-3m-Mesenchymal-Pericyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

AFF2 TRAIP C3orf20 BDNF PDZD2

2.03e-0517385536c8338463ee4cc432f568728d55989360f9a68d
ToppCellFetal_29-31_weeks-Immune-monocyte-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

HAVCR1 MYO9B TRABD VCAN UBASH3B

3.18e-05190855ad297172a74a80ed5c10f921e15efd1da0fd2d6b
ToppCell(09)_Interm._secr.>cil.-(2)_GFP_FOXI1|(09)_Interm._secr.>cil. / shred by cell type by condition

TPR BPTF RBBP6 BRD4 ANKRD26

3.96e-05199855fc680f85ebd3bab4c72876a19a461b0afb5f51ce
ToppCell(01)_IL1RL1+-(2)_GFP_FOXI1|(01)_IL1RL1+ / shred by cell type by condition

TPR BPTF RBBP6 BRD4 ANKRD26

3.96e-05199855a2f7d0cabf35b80fe239fae34a77bf9344d5d743
ComputationalNeighborhood of CDC2L5

TPR AFF2 MYO9B KIAA0586 NFRKB PHF21A

8.14e-05142556MORF_CDC2L5
Diseaseanxiety disorder (biomarker_via_orthology)

L1CAM BDNF

2.28e-053822DOID:2030 (biomarker_via_orthology)
Diseasechloride measurement

CEP83 NFAT5 BDNF

7.17e-0529823EFO_0009284
Diseasefeeling nervous measurement

MBD5 MGA ATF6B BDNF

1.03e-0487824EFO_0009597
DiseaseLDL cholesterol change measurement

APOB PKD1L3

1.59e-047822EFO_0007804
Diseasesodium measurement

DCDC1 CEP83 NFAT5 BDNF

1.99e-04103824EFO_0009282
Diseasemetabolic syndrome

HAVCR1 BPTF APOB NFAT5 BDNF

2.43e-04200825EFO_0000195
Diseaseconcentration of large LDL particles measurement

HAVCR1 APOB IGSF23

2.52e-0444823EFO_0022160
Diseasecholesterol in medium VLDL measurement

HAVCR1 APOB IGSF23

2.52e-0444823EFO_0022225
Diseaseglycoprotein measurement

ZFHX3 APOB UBASH3B PKD1L3

3.45e-04119824EFO_0004555
Diseaseapolipoprotein B to apolipoprotein A1 ratio

HAVCR1 APOB IGSF23

3.48e-0449823EFO_0021897
Diseaseattention deficit hyperactivity disorder, substance abuse, antisocial behaviour measurement

BPTF DCDC1 TRAIP ADGRB2 ELP1 ZFHX3 NFAT5 BDNF PHF21A

3.83e-04801829EFO_0003888, EFO_0007052, MONDO_0002491
Diseasetotal lipids in medium LDL

HAVCR1 APOB IGSF23

4.14e-0452823EFO_0022180
Diseasefeeling emotionally hurt measurement

CACNA1E MBD5 ATF6B

5.16e-0456823EFO_0009599
Diseasetriglycerides in LDL measurement

HAVCR1 BPTF APOB

5.16e-0456823EFO_0022320
DiseaseSjogren syndrome

TSBP1 NFAT5 C3orf20

6.31e-0460823EFO_0000699
Diseasetriglycerides in small VLDL measurement

HAVCR1 BPTF APOB

6.63e-0461823EFO_0022145
Diseasephospholipids in large VLDL measurement

HAVCR1 BPTF APOB

6.95e-0462823EFO_0022169
Diseasetriglycerides in medium LDL measurement

HAVCR1 BPTF APOB

6.95e-0462823EFO_0022322
Diseasetriglycerides in small LDL measurement

HAVCR1 BPTF APOB

7.98e-0465823EFO_0022323
DiseaseMicrocephaly

BRD4 TRAIP NUP214

8.72e-0467823C0025958
Diseasetriglycerides in very small VLDL measurement

HAVCR1 BPTF APOB

9.10e-0468823EFO_0022144
Diseasetotal cholesterol measurement, hematocrit, stroke, ventricular rate measurement, body mass index, atrial fibrillation, high density lipoprotein cholesterol measurement, coronary artery disease, diastolic blood pressure, triglyceride measurement, systolic blood pressure, heart failure, diabetes mellitus, glucose measurement, mortality, cancer

ANKRD26 ZFHX3 APOB

9.50e-0469823EFO_0000275, EFO_0000400, EFO_0000712, EFO_0001645, EFO_0003144, EFO_0004340, EFO_0004348, EFO_0004352, EFO_0004468, EFO_0004530, EFO_0004574, EFO_0004612, EFO_0006335, EFO_0006336, EFO_0007928, MONDO_0004992
DiseaseParoxysmal atrial fibrillation

HSPG2 BEST3 ZFHX3 MBD5

9.54e-04156824C0235480
Diseasefamilial atrial fibrillation

HSPG2 BEST3 ZFHX3 MBD5

9.54e-04156824C3468561
DiseasePersistent atrial fibrillation

HSPG2 BEST3 ZFHX3 MBD5

9.54e-04156824C2585653
DiseaseAtrial Fibrillation

HSPG2 BEST3 ZFHX3 MBD5

1.05e-03160824C0004238
Diseaseneuroimaging measurement, brain volume measurement

BPTF ATR VCAN ZNF521 NFAT5

1.23e-03286825EFO_0004346, EFO_0006930
DiseaseChronic myeloproliferative disorder

ATR TRAIP

1.27e-0319822C1292778
Diseaserisk-taking behaviour

CACNA1E BPTF DCDC1 ZFHX3 PKD1L3 NFAT5 BDNF PHF21A

1.29e-03764828EFO_0008579
Diseasesusceptibility to childhood ear infection measurement

TSBP1 TRAIP ELP1 BSN

1.34e-03171824EFO_0007904
Diseaseheart failure, diabetes mellitus, stroke, atrial fibrillation, mortality, coronary artery disease, cancer

ANKRD26 ZFHX3

1.40e-0320822EFO_0000275, EFO_0000400, EFO_0000712, EFO_0001645, EFO_0003144, EFO_0004352, MONDO_0004992
Diseasehaptoglobin measurement

ZFHX3 PKD1L3

1.55e-0321822EFO_0004640
DiseaseIntellectual Disability

CACNA1E BPTF BRD4 CIC BDNF PHF21A

1.55e-03447826C3714756
DiseaseSeckel syndrome

ATR TRAIP

1.70e-0322822C0265202
DiseaseAutism Spectrum Disorders

TET1 CIC BDNF

1.73e-0385823C1510586
Diseasecardiovascular disease

DCDC1 MYO9B LIN54 APOB UBASH3B NFAT5

1.73e-03457826EFO_0000319
Diseasesleep duration, low density lipoprotein cholesterol measurement

HAVCR1 APOB PKD1L3

2.11e-0391823EFO_0004611, EFO_0005271
Diseasesmoking cessation

CACNA1E ZFHX3 BSN NFAT5 BDNF

2.15e-03325825EFO_0004319
Diseasevisceral adipose tissue measurement

BPTF TSBP1 ADGRB2 PKD1L3 NFAT5 BDNF

2.24e-03481826EFO_0004765
Diseaseatopic dermatitis (is_implicated_in)

HAVCR1 BDNF

2.37e-0326822DOID:3310 (is_implicated_in)
Diseasereticulocyte count

ATR TSBP1 MYO9B NFRKB UBASH3B BSN MIDEAS WDSUB1 PDZD2

2.45e-031045829EFO_0007986
Diseaseapolipoprotein A 1 measurement

TRAIP LIN54 APOB UBASH3B PKD1L3 MGA MIDEAS BDNF

2.47e-03848828EFO_0004614
Diseaseapolipoprotein B measurement

HAVCR1 BPTF ZFHX3 APOB PKD1L3 MIDEAS IGSF23

2.48e-03663827EFO_0004615
Diseasecorpus callosum central volume measurement

WDSUB1 PDZD2

2.75e-0328822EFO_0010296
DiseaseAdenoid Cystic Carcinoma

VCAN SRCAP MGA

2.76e-03100823C0010606

Protein segments in the cluster

PeptideGeneStartEntry
PQSSVRTSPIKMPLV

BEST3

486

Q8N1M1
PRPPLAVTSRVMTVT

ADGRB2

831

O60241
AVTSRVMTVTVRPPT

ADGRB2

836

O60241
VMTVTVRPPTQPPAE

ADGRB2

841

O60241
TSRVMLSSQVPLEPP

BDNF

91

P23560
IPQPGTSLIPLVMVS

CATSPERD

416

Q86XM0
PQMVSDRTTPIIPLV

VCAN

371

P13611
MPRLTVDPQVVTDPS

CACNA1E

2001

Q15878
PTTVTTLRVPVFRPM

PPP2R2A

146

P63151
PAVTPDLIVQTPVMT

BRD4

226

O60885
PTFSPIPVMQTEILS

AFF2

776

P51816
SPRVQSTIPQPMIIR

FBXW10

901

Q5XX13
ATPLLQTAEIMTPPT

EDNRB

36

P24530
PRCPPQVVTVLMTTL

AP5Z1

691

O43299
PPVQMPSVISLARPV

ATF7

211

P17544
PSVISLARPVSMVPN

ATF7

216

P17544
SLILVPNMPPTASIN

CEP83

631

Q9Y592
SLFTTLTTRPVMEPP

ANKRD26

1596

Q9UPS8
QGTPTPLIPMLVIIE

MT-ATP6

131

P00846
PQIRPGMTVIRTPLQ

BPTF

2181

Q12830
TTSLPPRPETTIMRQ

HSPG2

251

P98160
RIMETSPTLLQIPPG

RAB11FIP5

636

Q9BXF6
PPELTMSTLINQIPE

PCDHB2

346

Q9Y5E7
RPLIPLGPTVVQTSM

ABHD14A

16

Q9BUJ0
TMVPTKSPVQPVVVE

DCDC1

1596

M0R2J8
DIVMTQTPLSLPVTP

IGKV2D-40

21

P01614
PTSMSRSPPTVLVIC

NAXE

101

Q8NCW5
MSSVSPIQIPSRLPL

LONP2

1

Q86WA8
KPVVVNTTPVRMSVP

LIN54

391

Q6MZP7
PTRITVPLSVISQPM

NFRKB

1181

Q6P4R8
VIPLNTSIVMPPRNL

ITM2B

166

Q9Y287
QKFSIRPSPVMVVTP

MGA

1566

Q8IWI9
RPSPVMVVTPVVSSE

MGA

1571

Q8IWI9
SVAPIIMAPTTIVTP

MSS51

16

Q4VC12
DIVMTQSPLSLPVTP

IGKV2D-28

21

P01615
LPITTQPASVLRPMV

BSN

2206

Q9UPA5
VPLTSLTRVPMIAPR

BSN

2236

Q9UPA5
IPTPTMTLASPVKRN

PDZD2

2451

O15018
QRPVMLTKFTPTTLP

PHF21A

261

Q96BD5
SSPVPSMVQKSPRIT

NUP214

656

P35658
VMEPPVITEQSPRRL

L1CAM

31

P32004
GPVITALTPMTIPDV

LONP1

106

P36776
VTVFRQTVVPPPMCT

ELP1

401

O95163
NIIPNALMTPLIPSS

NFAT5

586

O94916
IQQALTSPLPMTPIL

PHACTR4

421

Q8IZ21
PISRQQDPLMIPVTS

RBBP6

361

Q7Z6E9
VTIVSAMSTIIPPVP

GNAL

91

P38405
TIPEMRLPYTIITTP

APOB

3131

P04114
PLQSVMIPTLPSILG

ATR

2261

Q13535
PARVPLGITTVLTMS

GABRR1

311

P24046
VSEPVTISLPKPIMQ

IGSF23

121

A1L1A6
AVNMVPPPTCLSVIR

GFRAL

211

Q6UXV0
PLVVLMEPTFVQVPT

C3orf20

76

Q8ND61
PKVVIQTIPTVMPAS

ELF2

431

Q15723
MTSQPVPNETIIVLP

MS4A6A

1

Q9H2W1
GMVPLIIPVSVPVRT

MIDEAS

521

Q6PJG2
NIPLSPTLTTKSPVM

MBD5

296

Q9P267
VPIDVETVTSTPMPL

KANSL3

76

Q9P2N6
DIVMTQSPLSLPVTP

IGKV2-28

21

A0A075B6P5
DIVMTQTPLSLPVTP

IGKV2-40

21

A0A087WW87
PLMPRLVPQTAFTVT

EMSY

101

Q7Z589
ALIRPPQVTLTQTPM

TAF4

751

O00268
RMVITAPPVTNQPVT

TAF8

116

Q7Z7C8
PVIEPTLCMVSQTVP

STAT2

761

P52630
TTPSPREELMTTPIL

SMAGP

6

Q0VAQ4
TTVSTFVPPMPLPRQ

HAVCR1

206

Q96D42
SQPLPVITQLTMPVS

PKD1L3

226

Q7Z443
VAVIPRPEPMLRVTQ

SPINDOC

31

Q9BUA3
PLMIPTEASPSVLVV

TDRD7

456

Q8NHU6
VPQVLPASLMVSASP

SRCAP

1041

Q6ZRS2
TMPPPVRTTVVSAVP

SF3A1

581

Q15459
VRTTVVSAVPVMPRP

SF3A1

586

Q15459
TRSIMQPKTVFPPLT

TET1

1226

Q8NFU7
MPSRAVPPSTTVLLQ

ATF6B

256

Q99941
MVTNVVRPVSSTPVP

CIC

671

Q96RK0
RSVVPSVVPVPFDIM

ZNF440

491

Q8IYI8
FLLTTTPRPVIVEPM

PSPC1

221

Q8WXF1
SIRPMVTPATVTNPT

TPR

1696

P12270
EIMTVPPPSVSGRVS

TRABD

316

Q9H4I3
TQLKTPQVSPMPRIS

ZNF521

1171

Q96K83
LVVQPMLQSSPLSLP

PHC1

471

P78364
TVVKPSIVPVPFTIM

ZNF844

396

Q08AG5
SVPVMPLTSILPLQV

ZC3H7A

236

Q8IWR0
LSPTPVQTTMVLSKP

PLEKHG2

1226

Q9H7P9
TPLTIICQPMQPLRV

UBASH3B

361

Q8TF42
PMTNLVLPSAVLTPN

WDSUB1

446

Q8N9V3
PPMAPIIISQRTARI

TSBP1

181

Q5SRN2
PAIMLVNTPTVTPTT

KIAA0586

1091

Q9BVV6
IAPAQPSVPLTQLSM

ZFHX3

2076

Q15911
FIQPTDTVMIRPLPV

TRAIP

426

Q9BWF2
PTVTMPPREIVALVT

MYO7A

1671

Q13402
VKTPRRTPIMPTANI

MYO9B

2056

Q13459