Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	structural constituent of postsynaptic actin cytoskeleton	POTEF POTEE POTEI POTEJ	2.41e-07	11	106	4	GO:0098973
GeneOntologyMolecularFunction	structural constituent of postsynapse	POTEF POTEE POTEI POTEJ	2.41e-05	32	106	4	GO:0099186
GeneOntologyMolecularFunction	structural constituent of cytoskeleton	DSP POTEF SPTAN1 POTEE POTEI POTEJ	6.79e-05	130	106	6	GO:0005200
GeneOntologyMolecularFunction	structural constituent of synapse	POTEF POTEE POTEI POTEJ	7.19e-05	42	106	4	GO:0098918
GeneOntologyMolecularFunction	glycogen phosphorylase activity	PYGB PYGL	8.35e-05	3	106	2	GO:0008184
GeneOntologyMolecularFunction	1,4-alpha-oligoglucan phosphorylase activity	PYGB PYGL	2.76e-04	5	106	2	GO:0004645
GeneOntologyMolecularFunction	voltage-gated sodium channel activity	HCN1 SCN1A SCN2A	3.46e-04	26	106	3	GO:0005248
GeneOntologyMolecularFunction	protein serine kinase activity	DYRK1A TTK GSK3B TAOK3 MYO3B DYRK1B OXSR1 PRKG2	7.09e-04	363	106	8	GO:0106310
GeneOntologyMolecularFunction	tRNA methyltransferase activity	TRMT2B NSUN6 TRMT5	7.72e-04	34	106	3	GO:0008175
GeneOntologyBiologicalProcess	postsynaptic actin cytoskeleton organization	MYH10 POTEF POTEE POTEI POTEJ	4.75e-07	31	105	5	GO:0098974
GeneOntologyBiologicalProcess	postsynaptic cytoskeleton organization	MYH10 POTEF POTEE POTEI POTEJ	8.93e-07	35	105	5	GO:0099188
GeneOntologyBiologicalProcess	determination of adult lifespan	INPP5D MSH2 PRDM2 SCN1A SCN2A	8.06e-06	54	105	5	GO:0008340
GeneOntologyBiologicalProcess	peptidyl-threonine phosphorylation	DYRK1A TTK GSK3B MYO3B DYRK1B OXSR1	2.71e-05	115	105	6	GO:0018107
GeneOntologyBiologicalProcess	peptidyl-threonine modification	DYRK1A TTK GSK3B MYO3B DYRK1B OXSR1	4.33e-05	125	105	6	GO:0018210
GeneOntologyBiologicalProcess	protein targeting to vacuole	VPS8 ATG14 VPS13D VPS53	1.13e-04	49	105	4	GO:0006623
GeneOntologyCellularComponent	NuA4 histone acetyltransferase complex	POTEF POTEE POTEI POTEJ	1.87e-05	32	104	4	GO:0035267
GeneOntologyCellularComponent	H4/H2A histone acetyltransferase complex	POTEF POTEE POTEI POTEJ	1.87e-05	32	104	4	GO:0043189
GeneOntologyCellularComponent	axon	MYH10 TPRG1L HCN1 POTEF SPTAN1 DYRK1A GSK3B POTEE CYFIP1 SCN1A SCN2A PYGB MME POTEI POTEJ	3.42e-05	891	104	15	GO:0030424
GeneOntologyCellularComponent	H4 histone acetyltransferase complex	POTEF POTEE POTEI POTEJ	7.36e-05	45	104	4	GO:1902562
GeneOntologyCellularComponent	actin filament	POTEF INPP5D DYRK1A POTEE POTEI POTEJ	9.05e-05	146	104	6	GO:0005884
GeneOntologyCellularComponent	intercalated disc	DSP SPTAN1 SCN1A SCN2A	3.69e-04	68	104	4	GO:0014704
GeneOntologyCellularComponent	actin cytoskeleton	MYH10 POTEF INPP5D SPTAN1 DYRK1A POTEE MYO3B MYH16 POTEI POTEJ	5.98e-04	576	104	10	GO:0015629
GeneOntologyCellularComponent	supramolecular fiber	KIF18A MYH10 DSP POTEF INPP5D SPTAN1 DYRK1A GSK3B POTEE SCN1A ASPM POTEI POTEJ DNAH11 CHMP1A	7.20e-04	1179	104	15	GO:0099512
GeneOntologyCellularComponent	supramolecular polymer	KIF18A MYH10 DSP POTEF INPP5D SPTAN1 DYRK1A GSK3B POTEE SCN1A ASPM POTEI POTEJ DNAH11 CHMP1A	7.72e-04	1187	104	15	GO:0099081
GeneOntologyCellularComponent	cell-cell contact zone	DSP SPTAN1 SCN1A SCN2A	1.25e-03	94	104	4	GO:0044291
GeneOntologyCellularComponent	histone acetyltransferase complex	POTEF POTEE POTEI POTEJ	1.25e-03	94	104	4	GO:0000123
GeneOntologyCellularComponent	polymeric cytoskeletal fiber	KIF18A DSP POTEF INPP5D DYRK1A GSK3B POTEE ASPM POTEI POTEJ DNAH11 CHMP1A	1.70e-03	899	104	12	GO:0099513
GeneOntologyCellularComponent	protein acetyltransferase complex	POTEF POTEE POTEI POTEJ	1.82e-03	104	104	4	GO:0031248
GeneOntologyCellularComponent	fascia adherens	DSP SPTAN1	1.84e-03	13	104	2	GO:0005916
GeneOntologyCellularComponent	acetyltransferase complex	POTEF POTEE POTEI POTEJ	2.16e-03	109	104	4	GO:1902493
HumanPheno	Talipes valgus	HCN1 SCN1A SCN2A CHMP1A	1.29e-05	21	37	4	HP:0004684
HumanPheno	Tibial torsion	HCN1 SCN1A SCN2A TTI1	1.89e-05	23	37	4	HP:0100694
HumanPheno	Focal aware seizure	SCN1A SCN2A TLR3 KCNH5	4.26e-05	28	37	4	HP:0002349
HumanPheno	Cortical dysplasia	HCN1 SCN1A SCN2A ASNS ASPM	4.46e-05	56	37	5	HP:0002539
HumanPheno	Calcaneovalgus deformity	HCN1 SCN1A SCN2A CHMP1A	9.35e-05	34	37	4	HP:0001848
HumanPheno	Generalized cerebral atrophy/hypoplasia	HCN1 SCN1A SCN2A	9.60e-05	13	37	3	HP:0007058
HumanPheno	Deformed tarsal bones	HCN1 SCN1A SCN2A CHMP1A	1.05e-04	35	37	4	HP:0008119
Domain	ANK	POTEB3 POTEF POTEG POTED ANKRD30B POTEB2 POTEC ANKRD36B POTEE POTEM ANKRD18A ANKRD36 POTEI POTEJ POTEB	9.13e-12	251	104	15	SM00248
Domain	ANK_REPEAT	POTEB3 POTEF POTEG POTED ANKRD30B POTEB2 POTEC ANKRD36B POTEE POTEM ANKRD18A ANKRD36 POTEI POTEJ POTEB	1.02e-11	253	104	15	PS50088
Domain	ANK_REP_REGION	POTEB3 POTEF POTEG POTED ANKRD30B POTEB2 POTEC ANKRD36B POTEE POTEM ANKRD18A ANKRD36 POTEI POTEJ POTEB	1.08e-11	254	104	15	PS50297
Domain	Ankyrin_rpt	POTEB3 POTEF POTEG POTED ANKRD30B POTEB2 POTEC ANKRD36B POTEE POTEM ANKRD18A ANKRD36 POTEI POTEJ POTEB	1.68e-11	262	104	15	IPR002110
Domain	Ankyrin_rpt-contain_dom	POTEB3 POTEF POTEG ANKRD30B POTEB2 POTEC ANKRD36B POTEE POTEM ANKRD18A ANKRD36 POTEI POTEJ POTEB	1.39e-10	254	104	14	IPR020683
Domain	Ank_2	POTEB3 POTEF POTEG ANKRD30B POTEB2 POTEC ANKRD36B POTEE POTEM ANKRD18A ANKRD36 POTEI POTEJ	2.11e-10	215	104	13	PF12796
Domain	Ank	POTEF POTEG POTED ANKRD30B POTEC ANKRD36B POTEE POTEM ANKRD18A ANKRD36 POTEI POTEJ POTEB	4.36e-10	228	104	13	PF00023
Domain	-	POTEB3 POTEF POTEG ANKRD30B POTEB2 POTEC ANKRD36B POTEE POTEM ANKRD18A ANKRD36 POTEI POTEJ	1.22e-09	248	104	13	1.25.40.20
Domain	Actin_CS	POTEF POTEE POTEI POTEJ	1.57e-06	16	104	4	IPR004001
Domain	ACTINS_2	POTEF POTEE POTEI POTEJ	2.04e-06	17	104	4	PS00432
Domain	Actin/actin-like_CS	POTEF POTEE POTEI POTEJ	2.61e-06	18	104	4	IPR020902
Domain	ACTINS_ACT_LIKE	POTEF POTEE POTEI POTEJ	3.30e-06	19	104	4	PS01132
Domain	IQ_motif_EF-hand-BS	MYH10 SCN1A SCN2A MYO3B ASPM IQSEC1	1.10e-05	90	104	6	IPR000048
Domain	IQ	MYH10 SCN1A SCN2A MYO3B ASPM IQSEC1	1.33e-05	93	104	6	PS50096
Domain	Actin	POTEF POTEE POTEI POTEJ	2.54e-05	31	104	4	IPR004000
Domain	Actin	POTEF POTEE POTEI POTEJ	2.54e-05	31	104	4	PF00022
Domain	ACTIN	POTEF POTEE POTEI POTEJ	2.54e-05	31	104	4	SM00268
Domain	CNMP_BINDING_1	HCN1 SLC9C2 PRKG2 KCNH5	2.89e-05	32	104	4	PS00888
Domain	CNMP_BINDING_2	HCN1 SLC9C2 PRKG2 KCNH5	2.89e-05	32	104	4	PS00889
Domain	cNMP	HCN1 SLC9C2 PRKG2 KCNH5	3.70e-05	34	104	4	SM00100
Domain	cNMP_binding	HCN1 SLC9C2 PRKG2 KCNH5	3.70e-05	34	104	4	PF00027
Domain	cNMP-bd_dom	HCN1 SLC9C2 PRKG2 KCNH5	4.16e-05	35	104	4	IPR000595
Domain	CNMP_BINDING_3	HCN1 SLC9C2 PRKG2 KCNH5	4.16e-05	35	104	4	PS50042
Domain	IQ	MYH10 SCN1A MYO3B ASPM IQSEC1	4.73e-05	71	104	5	PF00612
Domain	cNMP-bd-like	HCN1 SLC9C2 PRKG2 KCNH5	5.79e-05	38	104	4	IPR018490
Domain	IQ	MYH10 SCN1A SCN2A MYO3B ASPM	8.90e-05	81	104	5	SM00015
Domain	PHOSPHORYLASE	PYGB PYGL	9.18e-05	3	104	2	PS00102
Domain	Phosphorylase	PYGB PYGL	9.18e-05	3	104	2	PF00343
Domain	Glycg_phsphrylas	PYGB PYGL	9.18e-05	3	104	2	IPR011833
Domain	Glyco_trans_35	PYGB PYGL	9.18e-05	3	104	2	IPR000811
Domain	-	HCN1 SLC9C2 PRKG2 KCNH5	1.46e-04	48	104	4	2.60.120.10
Domain	RmlC-like_jellyroll	HCN1 SLC9C2 PRKG2 KCNH5	1.85e-04	51	104	4	IPR014710
Domain	TPR-like_helical_dom	KIFBP TTC39C SRP72 TTK CFAP54 NUB1 CFAP46	3.27e-04	233	104	7	IPR011990
Domain	Na_trans_cytopl	SCN1A SCN2A	4.54e-04	6	104	2	PF11933
Domain	Na_trans_cytopl	SCN1A SCN2A	4.54e-04	6	104	2	IPR024583
Domain	Ser/Thr_kinase_AS	DYRK1A TTK GSK3B TAOK3 MYO3B DYRK1B OXSR1 PRKG2	8.62e-04	357	104	8	IPR008271
Domain	S_TKc	DYRK1A TTK GSK3B TAOK3 MYO3B DYRK1B OXSR1 PRKG2	8.94e-04	359	104	8	SM00220
Domain	PROTEIN_KINASE_ST	DYRK1A TTK GSK3B TAOK3 MYO3B DYRK1B OXSR1 PRKG2	9.43e-04	362	104	8	PS00108
Domain	-	KIFBP TTC39C SRP72 TTK CFAP54 CFAP46	1.06e-03	207	104	6	1.25.40.10
Domain	Protein_kinase_ATP_BS	DYRK1A TTK GSK3B TAOK3 MYO3B DYRK1B OXSR1 PRKG2	1.26e-03	379	104	8	IPR017441
Domain	Pkinase	DYRK1A TTK GSK3B TAOK3 MYO3B DYRK1B OXSR1 PRKG2	1.31e-03	381	104	8	PF00069
Domain	Na_channel_asu	SCN1A SCN2A	1.34e-03	10	104	2	IPR001696
Domain	Na_trans_assoc	SCN1A SCN2A	1.34e-03	10	104	2	IPR010526
Domain	Na_trans_assoc	SCN1A SCN2A	1.34e-03	10	104	2	PF06512
Domain	K_chnl_volt-dep_EAG/ELK/ERG	HCN1 KCNH5	2.68e-03	14	104	2	IPR003938
Domain	ATPase_dyneun-rel_AAA	MDN1 DNAH11	2.68e-03	14	104	2	IPR011704
Domain	AAA_5	MDN1 DNAH11	2.68e-03	14	104	2	PF07728
Domain	Kinase-like_dom	DYRK1A TTK GSK3B PRDM2 TAOK3 MYO3B DYRK1B OXSR1 PRKG2	3.27e-03	542	104	9	IPR011009
Domain	cNMP-bd_CS	HCN1 PRKG2	3.50e-03	16	104	2	IPR018488
Domain	Ion_trans_dom	HCN1 SCN1A SCN2A KCNH5	3.79e-03	114	104	4	IPR005821
Domain	Ion_trans	HCN1 SCN1A SCN2A KCNH5	3.79e-03	114	104	4	PF00520
Domain	Channel_four-helix_dom	SLC9C2 SCN1A SCN2A	3.95e-03	57	104	3	IPR027359
Domain	-	SLC9C2 SCN1A SCN2A	3.95e-03	57	104	3	1.20.120.350
Domain	PROTEIN_KINASE_ATP	DYRK1A TTK GSK3B TAOK3 MYO3B DYRK1B OXSR1 PRKG2	4.12e-03	459	104	8	PS00107
Domain	Myosin-like_IQ_dom	MYH10 ASPM	4.94e-03	19	104	2	IPR027401
Domain	-	MYH10 ASPM	4.94e-03	19	104	2	4.10.270.10
Pathway	BIOCARTA_SHH_PATHWAY	DYRK1A GSK3B DYRK1B	4.48e-05	15	67	3	MM1498
Pathway	BIOCARTA_SHH_PATHWAY	DYRK1A GSK3B DYRK1B	5.50e-05	16	67	3	M11792
Pathway	REACTOME_NEUTROPHIL_DEGRANULATION	DNAJC13 DSP SPTAN1 APAF1 PYHIN1 CYFIP1 PYGB PYGL C3 MME	1.39e-04	511	67	10	MM15330
Pubmed	POTE, a highly homologous gene family located on numerous chromosomes and expressed in prostate, ovary, testis, placenta, and prostate cancer.	POTEB3 POTED POTEB2 POTEC POTEJ POTEB	2.43e-14	8	110	6	12475935
Pubmed	Two novel transcripts encoding two Ankyrin repeat containing proteins have preponderant expression during the mouse spermatogenesis.	POTEG POTEB2 POTEC POTEM POTEB	1.73e-12	6	110	5	17171436
Pubmed	Identification of a novel actin isoform in hepatocellular carcinoma.	POTEF POTEG POTEE POTEM POTEI POTEJ	4.26e-12	15	110	6	16824795
Pubmed	Five POTE paralogs and their splice variants are expressed in human prostate and encode proteins of different lengths.	POTEB3 POTEG POTED POTEE POTEB	6.03e-12	7	110	5	15276201
Pubmed	Duplication and extensive remodeling shaped POTE family genes encoding proteins containing ankyrin repeat and coiled coil domains.	POTED POTEE POTEM POTEI POTEJ	3.60e-11	9	110	5	16364570
Pubmed	The Vertebrate Genome Annotation browser 10 years on.	POTEB3 POTEF POTEG POTEB2 POTEC POTEE POTEM POTEI POTEJ POTEB	1.21e-10	163	110	10	24316575
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	ARHGEF28 DSP POTEF SPTAN1 DYRK1A CC2D1A NSMCE2 TTK HDAC7 VPS13D MDN1 DYRK1B IQSEC1 NUB1 R3HDM1 AKAP1 ARHGAP19	1.89e-09	861	110	17	36931259
Pubmed	Evolution and expression of chimeric POTE-actin genes in the human genome.	POTEF POTEE POTEJ	3.08e-08	3	110	3	17101985
Pubmed	Identification and characterization of TSAP, a novel gene specifically expressed in testis during spermatogenesis.	POTEC POTEM POTEB	1.23e-07	4	110	3	17342726
Pubmed	In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.	MYH10 RPL34 DSP POTEF SPTAN1 UGGT1 ANKRD30B SRP72 RPL39L CCDC148 POTEE MDN1 ASPM MTTP TNFAIP8 POTEI POTEJ CCDC191 CFAP46	1.29e-07	1442	110	19	35575683
Pubmed	Direct interaction between hnRNP-M and CDC5L/PLRG1 proteins affects alternative splice site choice.	KIFBP DNAJC13 DSP SPTAN1 SRP72 MSH2 NUF2 TTK MDN1 OXSR1 CPSF2 RBM17	3.42e-07	582	110	12	20467437
Pubmed	Large-scale mapping of human protein-protein interactions by mass spectrometry.	KIFBP MYH10 RPL34 DSP UGGT1 DYRK1A MSH2 NUF2 HDAC7 GSK3B PPP1R7 RASGRP3 ASPM OXSR1 TNFAIP8 CPSF2 CHMP1A	5.98e-07	1284	110	17	17353931
Pubmed	Shotgun proteomics reveals specific modulated protein patterns in tears of patients with primary open angle glaucoma naïve to therapy.	POTEF FRMD4B POTEE C3 POTEI POTEJ	6.42e-07	96	110	6	23580065
Pubmed	Systematically defining selective autophagy receptor-specific cargo using autophagosome content profiling.	MYH10 DNAJC13 DSP SPTAN1 UGGT1 SRP72 HSPBP1 CMSS1 TTK GSK3B CYFIP1 BTF3 C3 OXSR1 AKAP1 RBM17 CHMP1A	6.87e-07	1297	110	17	33545068
Pubmed	An organelle-specific protein landscape identifies novel diseases and molecular mechanisms.	KIF18A KIFBP DNAJC13 DYRK1A MSH2 NUF2 HSPBP1 CCDC122 HDAC7 PPP1R7 CYFIP1 TTI1 PYGL C3 PRKG2 VPS53 ARHGAP19	8.84e-07	1321	110	17	27173435
Pubmed	Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.	MYH10 RPL34 DNAJC13 DSP SPTAN1 MSH2 CMSS1 GSK3B CYFIP1 MDN1 ASNS LTN1 ASPM IQSEC1 PYGB PYGL DDX43	1.22e-06	1353	110	17	29467282
Pubmed	CLEC16A interacts with retromer and TRIM27, and its loss impairs endosomal trafficking and neurodevelopment.	DNAJC13 UGGT1 DYRK1A HSPBP1 TTK VPS13D MDN1 DYRK1B IQSEC1 TTI1 VPS53	3.69e-06	606	110	11	36538041
Pubmed	LRRC31 inhibits DNA repair and sensitizes breast cancer brain metastasis to radiation therapy.	MYH10 DNAJC13 DSP UGGT1 MSH2 LTN1 MTTP	3.86e-06	202	110	7	33005030
Pubmed	CCT3 acts upstream of YAP and TFCP2 as a potential target and tumour biomarker in liver cancer.	MYH10 DSP POTEF SPTAN1 POTEE MYO3B POTEI POTEJ	3.96e-06	288	110	8	31501420
Pubmed	Nuclear actin interactome analysis links actin to KAT14 histone acetyl transferase and mRNA splicing.	MYH10 POTEF SPTAN1 MSH2 TTK CYFIP1 ASPM POTEI POTEJ RBM17	4.98e-06	506	110	10	30890647
Pubmed	∆F508 CFTR interactome remodelling promotes rescue of cystic fibrosis.	MYH10 RPL34 DSP SPTAN1 UGGT1 MDN1 LTN1 PYGB TTI1 PYGL C3	6.85e-06	647	110	11	26618866
Pubmed	In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine.	MYH10 POTEF CC2D1A GPD1L PPP1R7 POTEE CYFIP1 SLC12A1 PYGB PYGL C3 MME POTEI POTEJ	7.39e-06	1070	110	14	23533145
Pubmed	Inhibition of DYRK1A and GSK3B induces human β-cell proliferation.	DYRK1A GSK3B	9.91e-06	2	110	2	26496802
Pubmed	The Identification of Immune-Related Plasma Proteins Associated with Spontaneous Preterm Delivery and Intra-Amniotic Infection in Women with Premature Cervical Dilation or an Asymptomatic Short Cervix.	C3 IL6	9.91e-06	2	110	2	32080985
Pubmed	Neuronal death and perinatal lethality in voltage-gated sodium channel alpha(II)-deficient mice.	SCN1A SCN2A	9.91e-06	2	110	2	10827969
Pubmed	Differential role of sodium channels SCN1A and SCN2A gene polymorphisms with epilepsy and multiple drug resistance in the north Indian population.	SCN1A SCN2A	9.91e-06	2	110	2	19694741
Pubmed	Murine calmodulin binding protein 1 (Calmbp1): tissue-specific expression during development and in adult tissues.	APAF1 ASPM	9.91e-06	2	110	2	12351193
Pubmed	Epithelial cell adhesion molecules and epithelial mesenchymal transition (EMT) markers in Ewing's sarcoma family of tumors (ESFTs). Do they offer any prognostic significance?	DSP GSK3B	9.91e-06	2	110	2	22898789
Pubmed	Suppression of DYRK1A/B Drives Endoplasmic Reticulum Stress-mediated Autophagic Cell Death Through Metabolic Reprogramming in Colorectal Cancer Cells.	DYRK1A DYRK1B	9.91e-06	2	110	2	34969768
Pubmed	Differential expression of two sodium channel subtypes in human brain.	SCN1A SCN2A	9.91e-06	2	110	2	1317301
Pubmed	DNA polymerase eta is the sole contributor of A/T modifications during immunoglobulin gene hypermutation in the mouse.	POLH MSH2	9.91e-06	2	110	2	17190840
Pubmed	A primate-specific POTE-actin fusion protein plays a role in apoptosis.	POTEF POTEE	9.91e-06	2	110	2	19669888
Pubmed	Clinical exome sequencing identifies two novel mutations of the SCN1A and SCN2A genes in Moroccan patients with epilepsy: a case series.	SCN1A SCN2A	9.91e-06	2	110	2	31439038
Pubmed	Toll-Like Receptor-3 Mediates HIV-1-Induced Interleukin-6 Expression in the Human Brain Endothelium via TAK1 and JNK Pathways: Implications for Viral Neuropathogenesis.	TLR3 IL6	9.91e-06	2	110	2	29128906
Pubmed	TLR3 deletion limits mortality and disease severity due to Phlebovirus infection.	TLR3 IL6	9.91e-06	2	110	2	17056560
Pubmed	Severe epilepsy, retardation, and dysmorphic features with a 2q deletion including SCN1A and SCN2A.	SCN1A SCN2A	9.91e-06	2	110	2	15249644
Pubmed	Human cytomegalovirus utilises cellular dual-specificity tyrosine phosphorylation-regulated kinases during placental replication.	DYRK1A DYRK1B	9.91e-06	2	110	2	30501876
Pubmed	SCN1A and SCN2A polymorphisms are associated with response to valproic acid in Chinese epilepsy patients.	SCN1A SCN2A	9.91e-06	2	110	2	30693367
Pubmed	Association between SCN1A and SCN2A mutations and clinical/EEG features in Chinese patients from epilepsy or severe seizures.	SCN1A SCN2A	9.91e-06	2	110	2	29649454
Pubmed	Involvement of IL-6 and GSK3β in impaired sensorimotor gating induced by high-fat diet.	GSK3B IL6	9.91e-06	2	110	2	30326250
Pubmed	Phosphorylation and inactivation of glycogen synthase kinase 3β (GSK3β) by dual-specificity tyrosine phosphorylation-regulated kinase 1A (Dyrk1A).	DYRK1A GSK3B	9.91e-06	2	110	2	25477508
Pubmed	Conservation of structure and function between human and murine IL-16.	IL16 IL6	9.91e-06	2	110	2	9637508
Pubmed	Effects of SCN1A and SCN2A polymorphisms on responsiveness to valproic acid monotherapy in epileptic children.	SCN1A SCN2A	9.91e-06	2	110	2	33096315
Pubmed	Selective POTE paralogs on chromosome 2 are expressed in human embryonic stem cells.	POTEE POTEJ	9.91e-06	2	110	2	18447647
Pubmed	Missense mutations in sodium channel SCN1A and SCN2A predispose children to encephalopathy with severe febrile seizures.	SCN1A SCN2A	9.91e-06	2	110	2	26311622
Pubmed	Interleukin 6 influences germinal center development and antibody production via a contribution of C3 complement component.	C3 IL6	9.91e-06	2	110	2	9815267
Pubmed	Resistance to experimental autoimmune myasthenia gravis in IL-6-deficient mice is associated with reduced germinal center formation and C3 production.	C3 IL6	9.91e-06	2	110	2	12097416
Pubmed	The developmental changes of Na(v)1.1 and Na(v)1.2 expression in the human hippocampus and temporal lobe.	SCN1A SCN2A	9.91e-06	2	110	2	21377452
Pubmed	POTEE stimulates the proliferation of pancreatic cancer by activating the PI3K/Akt/GSK-3β/β-catenin signaling.	GSK3B POTEE	9.91e-06	2	110	2	32589786
Pubmed	Cytosolic Sensors of Viral RNA Are Involved in the Production of Interleukin-6 via Toll-Like Receptor 3 Signaling in Human Glomerular Endothelial Cells.	TLR3 IL6	9.91e-06	2	110	2	30808838
Pubmed	The combined role of galactose-deficient IgA1 and streptococcal IgA-binding M Protein in inducing IL-6 and C3 secretion from human mesangial cells: implications for IgA nephropathy.	C3 IL6	9.91e-06	2	110	2	24850720
Pubmed	KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.	IL16 MYH10 RPL34 DNAJC13 DSP SPTAN1 DYRK1A SRP72 GSK3B GPD1L PPP1R7 CYFIP1 SCN2A IQSEC1 PYGB DNAH11	1.13e-05	1431	110	16	37142655
Pubmed	Cross-Linking Mass Spectrometry Uncovers Interactions Between High-Density Lipoproteins and the SARS-CoV-2 Spike Glycoprotein.	MYH10 DSP SPTAN1 CFAP54 C3	1.14e-05	92	110	5	37343697
Pubmed	Association of SCN1A, SCN2A, and UGT2B7 Polymorphisms with Responsiveness to Valproic Acid in the Treatment of Epilepsy.	SCN1A SCN2A	2.97e-05	3	110	2	32185219
Pubmed	Clinical exome sequencing as the first-tier test for diagnosing developmental disorders covering both CNV and SNV: a Chinese cohort.	SCN1A SCN2A	2.97e-05	3	110	2	32005694
Pubmed	Glycogen synthase kinase-3 promotes the synergistic action of interferon-gamma on lipopolysaccharide-induced IL-6 production in RAW264.7 cells.	GSK3B IL6	2.97e-05	3	110	2	19258035
Pubmed	TBK1-associated protein in endolysosomes (TAPE) is an innate immune regulator modulating the TLR3 and TLR4 signaling pathways.	CC2D1A TLR3	2.97e-05	3	110	2	21189260
Pubmed	Genetic polymorphisms in non-alcoholic fatty liver disease: interleukin-6-174G/C polymorphism is associated with non-alcoholic steatohepatitis.	MTTP IL6	2.97e-05	3	110	2	19403348
Pubmed	SCN1A, SCN2A and SCN3A gene polymorphisms and responsiveness to antiepileptic drugs: a multicenter cohort study and meta-analysis.	SCN1A SCN2A	2.97e-05	3	110	2	23859570
Pubmed	IL-6 blocks a discrete early step in lymphopoiesis.	INPP5D IL6	2.97e-05	3	110	2	15831701
Pubmed	Intestinal permeability is reduced and IL-10 levels are increased in septic IL-6 knockout mice.	IL16 IL6	2.97e-05	3	110	2	11507020
Pubmed	Involvement of GSK-3beta and DYRK1B in differentiation-inducing factor-3-induced phosphorylation of cyclin D1 in HeLa cells.	GSK3B DYRK1B	2.97e-05	3	110	2	17046823
Pubmed	A novel DYRK1B inhibitor AZ191 demonstrates that DYRK1B acts independently of GSK3β to phosphorylate cyclin D1 at Thr(286), not Thr(288).	GSK3B DYRK1B	2.97e-05	3	110	2	24134204
Pubmed	Role of TLRs and IL-6 in the outcome of chronic hepatitis C treatment in Tunisian population.	TLR3 IL6	2.97e-05	3	110	2	28823914
Pubmed	Association of IL-6 rs1800795, but not TNF-α rs1800629, and IL-1β rs16944 polymorphisms' genotypes with recovery of ischemic stroke patients following thrombolysis.	IL16 IL6	2.97e-05	3	110	2	37853768
Pubmed	Glycogen Synthase Kinase 3β Regulates Antiviral Responses of TLR3 via TRAF2-Src Axis.	GSK3B TLR3	2.97e-05	3	110	2	31619538
Pubmed	A complement-IL-4 regulatory circuit controls liver regeneration.	C3 IL6	2.97e-05	3	110	2	22184721
Pubmed	Proline Hydroxylation Primes Protein Kinases for Autophosphorylation and Activation.	DYRK1A DYRK1B	2.97e-05	3	110	2	32640193
Pubmed	Nav1.2 is expressed in caudal ganglionic eminence-derived disinhibitory interneurons: Mutually exclusive distributions of Nav1.1 and Nav1.2.	SCN1A SCN2A	2.97e-05	3	110	2	28784306
Pubmed	Sodium channels SCN1A, SCN2A and SCN3A in familial autism.	SCN1A SCN2A	2.97e-05	3	110	2	12610651
Pubmed	Evaluation of blood-brain barrier function by quotient alpha2 macroglobulin and its relationship with interleukin-6 and complement component 3 levels in neuropsychiatric systemic lupus erythematosus.	C3 IL6	2.97e-05	3	110	2	29036223
Pubmed	IL-6 Enhances the Activation of PI3K-AKT/mTOR-GSK-3β by Upregulating GRPR in Hippocampal Neurons of Autistic Mice.	GSK3B IL6	2.97e-05	3	110	2	38536552
Pubmed	CELL DIVISION CYCLE. Kinetochore attachment sensed by competitive Mps1 and microtubule binding to Ndc80C.	NUF2 TTK	2.97e-05	3	110	2	26068854
Pubmed	Cigarette smoke attenuates the RIG-I-initiated innate antiviral response to influenza infection in two murine models.	TLR3 IL6	2.97e-05	3	110	2	25260755
Pubmed	DCAF7/WDR68 is required for normal levels of DYRK1A and DYRK1B.	DYRK1A DYRK1B	2.97e-05	3	110	2	30496304
Pubmed	Viral-like TLR3 induction of cytokine networks and α-synuclein are reduced by complement C3 blockade in mouse brain.	TLR3 C3	2.97e-05	3	110	2	37704739
Pubmed	Multidrug resistance in epilepsy and polymorphisms in the voltage-gated sodium channel genes SCN1A, SCN2A, and SCN3A: correlation among phenotype, genotype, and mRNA expression.	SCN1A SCN2A	2.97e-05	3	110	2	18784617
Pubmed	Characterization of 5' untranslated regions of the voltage-gated sodium channels SCN1A, SCN2A, and SCN3A and identification of cis-conserved noncoding sequences.	SCN1A SCN2A	2.97e-05	3	110	2	17544618
Pubmed	NUB1 modulation of GSK3β reduces tau aggregation.	GSK3B NUB1	2.97e-05	3	110	2	22965877
Pubmed	Variable patterns of mutation density among NaV1.1, NaV1.2 and NaV1.6 point to channel-specific functional differences associated with childhood epilepsy.	SCN1A SCN2A	2.97e-05	3	110	2	32845893
Pubmed	DYRK1A and glycogen synthase kinase 3beta, a dual-kinase mechanism directing proteasomal degradation of CRY2 for circadian timekeeping.	DYRK1A GSK3B	2.97e-05	3	110	2	20123978
Pubmed	Toll-like receptor 3 mediates West Nile virus entry into the brain causing lethal encephalitis.	TLR3 IL6	2.97e-05	3	110	2	15558055
Pubmed	Complement-dependent acute-phase expression of C-reactive protein and serum amyloid P-component.	C3 IL6	2.97e-05	3	110	2	10878380
Pubmed	Comparison and optimization of in silico algorithms for predicting the pathogenicity of sodium channel variants in epilepsy.	SCN1A SCN2A	2.97e-05	3	110	2	28518218
Pubmed	Gene-to-gene interaction between sodium channel-related genes in determining the risk of antiepileptic drug resistance.	SCN1A SCN2A	2.97e-05	3	110	2	19270815
Pubmed	DYRK1A binds to an evolutionarily conserved WD40-repeat protein WDR68 and induces its nuclear translocation.	DYRK1A DYRK1B	2.97e-05	3	110	2	21777625
Pubmed	Association of SCN1A, SCN2A and ABCC2 gene polymorphisms with the response to antiepileptic drugs in Chinese Han patients with epilepsy.	SCN1A SCN2A	2.97e-05	3	110	2	25155934
Pubmed	Reduced sodium current in Purkinje neurons from Nav1.1 mutant mice: implications for ataxia in severe myoclonic epilepsy in infancy.	SCN1A SCN2A	2.97e-05	3	110	2	17928448
Pubmed	Early expression of sodium channel transcripts and sodium current by cajal-retzius cells in the preplate of the embryonic mouse neocortex.	SCN1A SCN2A	2.97e-05	3	110	2	14973256
Pubmed	Large-scale characterization of HeLa cell nuclear phosphoproteins.	DNAJC13 DSP SPTAN1 HDAC7 GSK3B PRDM2 MDN1 IQSEC1 OXSR1 CPSF2 AKAP1	3.57e-05	774	110	11	15302935
Pubmed	Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.	MYH10 DSP SPTAN1 UGGT1 SRP72 MSH2 MDN1 ASNS PYGB PYGL	4.43e-05	653	110	10	22586326
Pubmed	RSPO-LGR4 functions via IQGAP1 to potentiate Wnt signaling.	MYH10 DNAJC13 POTEF POLH UGGT1 POTEJ	4.62e-05	202	110	6	24639526
Pubmed	A high-throughput approach for measuring temporal changes in the interactome.	KIFBP SPTAN1 UGGT1 SRP72 MSH2 HSPBP1 PPP1R7 CYFIP1 BTF3 ASNS PYGB TTI1 PYGL OXSR1 TNFAIP8	5.51e-05	1455	110	15	22863883
Pubmed	Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.	KIFBP MYH10 DNAJC13 HCN1 SPTAN1 DYRK1A GSK3B PPP1R7 CYFIP1 MDN1 IQSEC1 CPSF2	5.55e-05	963	110	12	28671696
Pubmed	Nav1.1 localizes to axons of parvalbumin-positive inhibitory interneurons: a circuit basis for epileptic seizures in mice carrying an Scn1a gene mutation.	SCN1A SCN2A	5.92e-05	4	110	2	17537961
Pubmed	Targeted DNA Sequencing from Autism Spectrum Disorder Brains Implicates Multiple Genetic Mechanisms.	SCN1A SCN2A	5.92e-05	4	110	2	26637798
Pubmed	Impaired phosphorylation of Na(+)-K(+)-2Cl(-) cotransporter by oxidative stress-responsive kinase-1 deficiency manifests hypotension and Bartter-like syndrome.	SLC12A1 OXSR1	5.92e-05	4	110	2	21972418
Pubmed	The hMsh2-hMsh6 complex acts in concert with monoubiquitinated PCNA and Pol η in response to oxidative DNA damage in human cells.	POLH MSH2	5.92e-05	4	110	2	21855803
Pubmed	Differential maturation and chaperone dependence of the paralogous protein kinases DYRK1A and DYRK1B.	DYRK1A DYRK1B	5.92e-05	4	110	2	35165364
Pubmed	Altered expression of regulators of the cortical chloride transporters NKCC1 and KCC2 in schizophrenia.	SLC12A1 OXSR1	5.92e-05	4	110	2	20819979
Interaction	POTEC interactions	POTEB3 POTEF POTEG POTED POTEC	5.01e-09	13	108	5	int:POTEC
Interaction	POTED interactions	POTEB3 POTED POTEC	5.96e-07	4	108	3	int:POTED
Interaction	POTEB3 interactions	POTEB3 POTEF POTED POTEB2 POTEC	1.15e-06	35	108	5	int:POTEB3
Interaction	ACTG2 interactions	MYH10 POTEF POTEE POTEI POTEJ	6.36e-06	49	108	5	int:ACTG2
Interaction	PLEKHF1 interactions	KIFBP TNFAIP8 POTEI	2.39e-05	11	108	3	int:PLEKHF1
Interaction	POTEG interactions	POTEF POTEG POTEC	3.18e-05	12	108	3	int:POTEG
Interaction	SNW1 interactions	KIFBP DNAJC13 DSP SPTAN1 SRP72 MSH2 NUF2 HSPBP1 TTK MDN1 MTTP OXSR1 CPSF2 RBM17	4.55e-05	747	108	14	int:SNW1
Interaction	PPP1R3F interactions	DYRK1A DYRK1B PYGB	6.50e-05	15	108	3	int:PPP1R3F
Interaction	YWHAH interactions	ARHGEF28 DSP POTEF SPTAN1 DYRK1A CC2D1A NSMCE2 TTK HDAC7 PYHIN1 VPS13D CYFIP1 BTF3 NUB1 R3HDM1 AKAP1 ARHGAP19	7.63e-05	1102	108	17	int:YWHAH
Cytoband	2q21.1	POTEF POTEE POTEI POTEJ	1.20e-05	58	110	4	2q21.1
Cytoband	Ensembl 112 genes in cytogenetic band chr2q21	POTEF POTEE POTEI POTEJ R3HDM1	3.34e-05	151	110	5	chr2q21
Cytoband	7p21	IL6 DNAH11	8.48e-05	6	110	2	7p21
Cytoband	5q13.2	ARHGEF28 BTF3 PTCD2	3.21e-04	55	110	3	5q13.2
Cytoband	Ensembl 112 genes in cytogenetic band chr2q11	TSGA10 ANKRD36C ANKRD36B ANKRD36	5.20e-04	153	110	4	chr2q11
Cytoband	2q24.3	SCN1A SCN2A	6.68e-04	16	110	2	2q24.3
Cytoband	2q11.2	TSGA10 ANKRD36B ANKRD36	7.08e-04	72	110	3	2q11.2
Cytoband	Ensembl 112 genes in cytogenetic band chr15q11	POTEB3 POTEB2 CYFIP1 POTEB	1.90e-03	217	110	4	chr15q11
Cytoband	Ensembl 112 genes in cytogenetic band chr2q24	CCDC148 SCN1A SCN2A	3.60e-03	127	110	3	chr2q24
Cytoband	3q22.1	DNAJC13 RPL39P5	4.60e-03	42	110	2	3q22.1
GeneFamily	Ankyrin repeat domain containing\|POTE ankyrin domain containing	POTEF POTEG POTED POTEB2 POTEC POTEE POTEM POTEI POTEJ POTEB	1.10e-22	13	70	10	685
GeneFamily	Ankyrin repeat domain containing	POTEF POTEG POTED ANKRD30B ANKRD36C POTEB2 POTEC ANKRD36B POTEE POTEM ANKRD18A ANKRD36 POTEI POTEJ POTEB	1.93e-14	242	70	15	403
GeneFamily	Glycogen phosphorylases	PYGB PYGL	4.42e-05	3	70	2	437
GeneFamily	Sodium voltage-gated channel alpha subunits	SCN1A SCN2A	5.23e-04	9	70	2	1203
GeneFamily	Tetratricopeptide repeat domain containing\|Bardet-Biedl syndrome associated\|BBSome	KIFBP TTC39C SRP72 CFAP46	1.03e-03	115	70	4	769
GeneFamily	Myosin heavy chains	MYH10 MYH16	1.50e-03	15	70	2	1098
Coexpression	RODRIGUES_THYROID_CARCINOMA_ANAPLASTIC_UP	KIF18A DNAJC13 TTC39C POLH NUF2 CMSS1 TTK GSK3B ASNS ASPM MME CPSF2 TRMT5 MAGEC2	1.80e-06	721	109	14	M10237
Coexpression	FAN_EMBRYONIC_CTX_EX_4_EXCITATORY_NEURON	CC2D1A ANKRD36B SCN2A ANKRD18A ANKRD36 R3HDM1 RAPGEFL1	6.24e-06	166	109	7	M39026
Coexpression	GSE37532_TREG_VS_TCONV_PPARG_KO_CD4_TCELL_FROM_VISCERAL_ADIPOSE_TISSUE_UP	TTC39C INPP5D FRMD4B ASNS OXSR1 CPSF2 AKAP1	2.09e-05	200	109	7	M8955
Coexpression	DESCARTES_ORGANOGENESIS_EPENDYMAL_CELL	POTEG POTEB2 POTEC CCDC148 CFAP54 POTEM POTEB CFAP46	2.42e-05	282	109	8	MM3642
Coexpression	RAO_BOUND_BY_SALL4_ISOFORM_B	POTEB3 POTEF POTEG POTEB2 POTEC POTEE POTEM POTEI POTEJ AKAP1 POTEB	3.27e-05	584	109	11	MM1080
Coexpression	BENPORATH_PROLIFERATION	UGGT1 MSH2 NUF2 CMSS1 TTK ASPM	3.54e-05	147	109	6	M2114
Coexpression	HE_LIM_SUN_FETAL_LUNG_C6_DEUTEROSOMAL_CELL	KIF18A POLH NUF2 RPL39L TTK ASPM PYGL	3.96e-05	221	109	7	M45789
Coexpression	DARWICHE_PAPILLOMA_PROGRESSION_RISK	DYRK1A POTEB2 POTEC POTEM POTEB	4.18e-05	92	109	5	MM503
Coexpression	HE_LIM_SUN_FETAL_LUNG_C5_LARGE_PRE_B_CELL	KIF18A TTC39C CC2D1A MSH2 NUF2 HSPBP1 ANKRD36C CMSS1 NSMCE2 RPL39L TTK ANKRD36B PPP1R7 ASPM TTI1 ANKRD36 CPSF2	4.69e-05	1363	109	17	M45782
CoexpressionAtlas	dev gonad_e12.5_F_GermCellOvary_Oct_top-relative-expression-ranked_500	KIF18A DNAJC13 DSP ATG14 MSH2 RPL39L TTK MDN1 ASNS DDX43 CCDC191 ARHGAP19	9.80e-07	406	107	12	gudmap_dev gonad_e12.5_F_GermCellOvary_Oct_500
CoexpressionAtlas	dev gonad_e11.5_F_PrimGermCell_Oct_top-relative-expression-ranked_1000	KIF18A DNAJC13 DSP ATG14 MSH2 RPL39L TTK MDN1 ASNS DDX43 OXSR1 TRMT5 AKAP1 CCDC191 ARHGAP19	1.13e-05	799	107	15	gudmap_dev gonad_e11.5_F_PrimGermCell_Oct_1000
CoexpressionAtlas	B cells, B.GC.Sp, CD19+ IgM+ IgD- GL7+ PNA+, Spleen, avg-3	KIF18A POLH NUF2 TTK RASSF6 RASGRP3 ASNS ASPM CPSF2 ARHGAP19	2.25e-05	380	107	10	GSM538207_500
CoexpressionAtlas	dev gonad_e12.5_M_GermCellTestis_Oct_top-relative-expression-ranked_500	KIF18A DNAJC13 ATG14 MSH2 RPL39L TTK MDN1 DDX43 CCDC191 ARHGAP19	2.63e-05	387	107	10	gudmap_dev gonad_e12.5_M_GermCellTestis_Oct_500
CoexpressionAtlas	dev gonad_e12.5_F_GermCellOvary_Oct_top-relative-expression-ranked_1000	KIF18A DNAJC13 DSP ATG14 MSH2 RPL39L TTK MDN1 ASNS DDX43 TRMT5 AKAP1 CCDC191 ARHGAP19	6.56e-05	822	107	14	gudmap_dev gonad_e12.5_F_GermCellOvary_Oct_1000
CoexpressionAtlas	dev gonad_e11.5_F_PrimGermCell_Oct_k-means-cluster#3_top-relative-expression-ranked_1000	DNAJC13 ATG14 MSH2 RPL39L TTK MDN1 OXSR1 TRMT5 CCDC191 ARHGAP19	1.17e-04	463	107	10	gudmap_dev gonad_e11.5_F_PrimGermCell_Oct_k3_1000
CoexpressionAtlas	dev gonad_e11.5_M_PrimGermCell_Oct_top-relative-expression-ranked_500	KIF18A DSP MSH2 RPL39L TTK MDN1 ASNS CCDC191 ARHGAP19	1.21e-04	376	107	9	gudmap_dev gonad_e11.5_M_PrimGermCell_Oct_500
CoexpressionAtlas	dev gonad_e11.5_F_PrimGermCell_Oct_top-relative-expression-ranked_500	KIF18A DSP MSH2 RPL39L TTK MDN1 ASNS DDX43 ARHGAP19	1.48e-04	386	107	9	gudmap_dev gonad_e11.5_F_PrimGermCell_Oct_500
CoexpressionAtlas	dev gonad_e11.5_M_PrimGermCell_Oct_top-relative-expression-ranked_1000	KIF18A DNAJC13 DSP ATG14 MSH2 RPL39L TTK MDN1 ASNS DDX43 AKAP1 CCDC191 ARHGAP19	1.53e-04	781	107	13	gudmap_dev gonad_e11.5_M_PrimGermCell_Oct_1000
CoexpressionAtlas	dev gonad_e12.5_F_GermCellOvary_Oct_k-means-cluster#4_top-relative-expression-ranked_500	DNAJC13 ATG14 MSH2 MDN1 CCDC191	1.60e-04	101	107	5	gudmap_dev gonad_e12.5_F_GermCellOvary_Oct_k4_500
CoexpressionAtlas	dev gonad_e12.5_M_GermCellTestis_Oct_top-relative-expression-ranked_1000	KIF18A DNAJC13 ATG14 MSH2 NUF2 RPL39L TTK MDN1 ASNS DDX43 TRMT5 CCDC191 ARHGAP19	1.82e-04	795	107	13	gudmap_dev gonad_e12.5_M_GermCellTestis_Oct_1000
ToppCell	TCGA-Brain-Primary_Tumor-Glioblastoma-Primary_GBM-11\|TCGA-Brain / Sample_Type by Project: Shred V9	POTEF POTEG POTEE POTEI POTEJ	4.78e-07	63	109	5	d7dc1356a60cb527fe668328d5375f352239d911
ToppCell	PBMC-Control-Hematopoietic-Platelet-Platelet-plt_5\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	POTEG POTEC CFAP54 POTEM POTEJ KCNH5	1.07e-06	136	109	6	27a41463e6f16deb5b1d4f17fefded9959038c07
ToppCell	PBMC-Control-Hematopoietic-Platelet-Platelet-plt_5\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	POTEG POTEC CFAP54 POTEM POTEJ KCNH5	1.07e-06	136	109	6	88b5c839d0446c6d6b7e81fc4d48f5e7e96eea11
ToppCell	10x5'-Lung-Lymphocytic_T_CD4-T_CD4/CD8\|Lung / Manually curated celltypes from each tissue	CERKL CCDC148 ANKRD36B ANKRD36 CFAP46 DNAH11	2.38e-06	156	109	6	10d191e29b16cae8238e8df6c0ff38882253f34e
ToppCell	COVID-19_Moderate-multiplets\|World / disease group, cell group and cell class	ANKRD36C ANKRD36B POTEE TLR3 ANKRD18A ANKRD36	2.38e-06	156	109	6	afdc025fa75e7926b1cc182c4a33654a2186abb1
ToppCell	18-Distal-Epithelial-Basal_cell\|Distal / Age, Tissue, Lineage and Cell class	DNAJC13 DSP UGGT1 CCDC122 RASSF6 MYO3B	2.56e-06	158	109	6	183f445967e09e871c93d8e94781ed9fec894169
ToppCell	TCGA-Breast-Primary_Tumor-Breast_Carcinoma-Infiltrating_Lobular_Carcinoma-9\|TCGA-Breast / Sample_Type by Project: Shred V9	POTEF POTEE POTEM POTEI POTEJ	2.84e-06	90	109	5	96e836c7a1df279ac812b7c3aa75e6b81b614244
ToppCell	PND03-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_T-CD4_T-CD4_T_G2M\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	KIF18A NUF2 TTK ASPM DDX43 ARHGAP19	3.91e-06	170	109	6	2d5e56eee0c3ce75a9641cc14dee0e0807141c32
ToppCell	COVID-19-kidney-Distal_Epi_Doublet_(PCT)\|COVID-19 / Disease (COVID-19 only), tissue and cell type	ARHGEF28 CCDC148 SLC12A1 RASSF6 SCN2A MYO3B	5.78e-06	182	109	6	9d67717a6e13bcb54c1297a3e4e3abf4e51628a3
ToppCell	Adult-Epithelial-ciliated_cell-D175\|Adult / Lineage, Cell type, age group and donor	CERKL TSGA10 SLC9C2 CFAP54 CFAP46 DNAH11	6.35e-06	185	109	6	30f4980dee6cd5959655f8d74049f3bfb5312611
ToppCell	COVID-19-Epithelial_cells-Airway_ciliated\|COVID-19 / group, cell type (main and fine annotations)	CERKL SLC9C2 CCDC148 CFAP54 CFAP46 DNAH11	6.35e-06	185	109	6	18a40f0a338aa398d81384b5159fb80ce8a2020c
ToppCell	Adult-Epithelial-ciliated_cell-D231\|Adult / Lineage, Cell type, age group and donor	CERKL SLC9C2 CCDC148 CFAP54 CFAP46 DNAH11	6.96e-06	188	109	6	34b11f72ca73153d02edcd09b38983ad1a504659
ToppCell	Adult-Epithelial-ciliated_cell\|Adult / Lineage, Cell type, age group and donor	CERKL SLC9C2 CCDC148 CFAP54 CFAP46 DNAH11	7.18e-06	189	109	6	b679920f0993e917dd86da082113bfbd85ea1ca5
ToppCell	COVID-19-lung-Ciliated\|lung / Disease (COVID-19 only), tissue and cell type	CERKL SLC9C2 CCDC148 CFAP54 CFAP46 DNAH11	7.18e-06	189	109	6	27329c4661aebabd19fac7fe5dca263fe99d76f3
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Thick_Ascending_Limb_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	HDAC7 CCDC148 CFAP54 SLC12A1 MYO3B PYGB	7.62e-06	191	109	6	5a67ff17fb4b9eff641176dff07830c9cd73754e
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	HDAC7 CCDC148 CFAP54 SLC12A1 MYO3B PYGB	7.62e-06	191	109	6	55ab2854a02cdcfc395e49870ccb7290b5e5471d
ToppCell	H1299-infected\|H1299 / Cell line, Condition and Strain	POLH ANKRD36C MDN1 ASPM ANKRD18A ANKRD36	7.85e-06	192	109	6	9cf8049bdc3e0f81ce69042beac72b08d8f38b4e
ToppCell	human_hepatoblastoma-Tumor_cells-T1\|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)	KIF18A MSH2 NUF2 CMSS1 TTK ASPM	8.09e-06	193	109	6	4b9fa2a4424f8abe63fa7bee78db93dda04ab15f
ToppCell	PSB-critical-LOC-Epithelial-FOXN4+\|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	KIF18A NUF2 RPL39L TTK ASPM PYGL	8.09e-06	193	109	6	b7d9c5bed524423e92f01496a9f8fad11b33a3f7
ToppCell	systemic_lupus_erythematosus-flare-Lymphocytic_B-B_mem\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	HCN1 POTEG POTEM RASSF6 RASGRP3 TNFAIP8	8.33e-06	194	109	6	40c7f9bd69a8e843b81972e25a67f591021415dd
ToppCell	3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.3.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	TSGA10 CFAP54 ANKRD18A CCDC191 CFAP46 DNAH11	8.33e-06	194	109	6	4a2c127c90d1fefe604fcb9e796577d21b489dd6
ToppCell	367C-Myeloid-Macrophage-FABP4+_Macrophage_proliferating\|367C / Donor, Lineage, Cell class and subclass (all cells)	KIF18A ARHGEF28 NUF2 RPL39L TTK ASPM	8.33e-06	194	109	6	a12b64945e10f00aa983678a02586c59badc1570
ToppCell	Dividing_cells\|World / Immune cells in Kidney/Urine in Lupus Nephritis	KIF18A NUF2 RPL39L TTK ASPM ARHGAP19	8.58e-06	195	109	6	79ee423df85aa1631b7bdea74eacaf826dfc4a2c
ToppCell	Dividing_cells-Dividing_cells\|World / Immune cells in Kidney/Urine in Lupus Nephritis	KIF18A NUF2 RPL39L TTK ASPM ARHGAP19	8.58e-06	195	109	6	19829760dfcc0edafd2a2bd80f424a45d039af1f
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	MYH10 HCN1 ANKRD36B SCN2A ANKRD36 R3HDM1	8.83e-06	196	109	6	676c56b44ac29f7baecb62f49bb8597cc74c0a88
ToppCell	PND10-Endothelial-Endothelial_blood-vessel-Microvascular_EC-EPC-EPC_G2M\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	KIF18A NUF2 TTK RASGRP3 ASPM ARHGAP19	8.83e-06	196	109	6	20383d576708b7e4bfce3e9fe40548cce496e3cb
ToppCell	356C-Myeloid-Macrophage-FABP4+_Macrophage_proliferating_2\|Myeloid / Donor, Lineage, Cell class and subclass (all cells)	KIF18A ARHGEF28 NUF2 RPL39L ASPM MME	8.83e-06	196	109	6	34bd155e6d848eb53d613997c0e244535de30ba3
ToppCell	PND10-Endothelial-Endothelial_blood-vessel-Microvascular_EC-EPC\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	KIF18A NUF2 TTK RASGRP3 ASPM ARHGAP19	8.83e-06	196	109	6	0644bd14a944b9c9759a295dfdd5e67a4775f20a
ToppCell	(3)_MNP-(3)_Macrophage_Dividing\|(3)_MNP / Lung cell shreds - cell class (v4) and cell subclass (v4)	KIF18A ARHGEF28 NUF2 RPL39L TTK ASPM	9.09e-06	197	109	6	048bc4f8fd5d4f394e2384700640f72042336597
ToppCell	LPS_anti-TNF-Epithelial_alveolar-AT_2-Differentiating_AT2\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	ARHGEF28 DSP SCN1A C3 MME AKAP1	9.09e-06	197	109	6	1485933986921ff45669d9b7501c8d17050b3e97
ToppCell	3'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.2\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	TSGA10 SLC9C2 CFAP54 CCDC191 CFAP46 DNAH11	9.09e-06	197	109	6	74a2c6cb8fcfe53dd9a2b36492a16c58f38e51c9
ToppCell	Primary_Visual_cortex_(V1C)-Neuronal\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	MYH10 HCN1 SPTAN1 SCN1A SCN2A R3HDM1	9.36e-06	198	109	6	8ab40fae14fe02e39bc8c8da187a5cd60c787643
ToppCell	(7)_Epithelial_cells-(7)_Epithelial-B_(AT2)\|(7)_Epithelial_cells / Lung cell shreds - cell class (v4) and cell subclass (v4)	RPL34 BTF3 SCN1A ASNS C3 AKAP1	9.36e-06	198	109	6	391f59e232269f6ae9f8792d21a60ad534e03c4d
ToppCell	3'-Child04-06-SmallIntestine-Hematopoietic-B_cells-Cycling_plasma_cell\|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	KIF18A POLH NUF2 RPL39L TTK ASPM	9.63e-06	199	109	6	c9d15c84b9f8c87b4ea0008be7d5efc5f45efd1a
ToppCell	Bronchus_Control_(B.)-Epithelial-TX-Ciliated\|Bronchus_Control_(B.) / Sample group, Lineage and Cell type	TSGA10 CFAP54 ANKRD18A CCDC191 CFAP46 DNAH11	9.91e-06	200	109	6	6a2ccc71a0cbe04a542c379b28b5006de53981c3
ToppCell	mild-T/NK_proliferative\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	KIF18A MSH2 NUF2 ANKRD36C TTK ASPM	9.91e-06	200	109	6	63cc57b9331459efbb73051d174d198a3568b938
ToppCell	PBMC-Control-Lymphocyte-B-B_cell-B_naive-B_activate-7\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	DSP RASGRP3 C19orf44 CCDC191 IL6	2.28e-05	138	109	5	76be06136c83c167cedece7515228ed4d29dd1f0
ToppCell	Frontal_cortex-Macroglia-POLYDENDROCYTE-P4-Tnr\|Frontal_cortex / BrainAtlas - Mouse McCarroll V32	NUF2 TTK ASPM DDX43 DNAH11	2.62e-05	142	109	5	7bd05d0c0ac2dee0e6cc0f3c531f9154bf300c75
ToppCell	Frontal_cortex-Macroglia-POLYDENDROCYTE-P4\|Frontal_cortex / BrainAtlas - Mouse McCarroll V32	NUF2 TTK ASPM DDX43 DNAH11	2.62e-05	142	109	5	328d08ba2712cd42bb9846ac4d7453ae165b75e2
ToppCell	Frontal_cortex-Macroglia-POLYDENDROCYTE-P4-Tnr-Polydendrocyte.Tnr.Dlx1_(Dlx1)-\|Frontal_cortex / BrainAtlas - Mouse McCarroll V32	NUF2 TTK ASPM DDX43 DNAH11	2.62e-05	142	109	5	94774d3e598d074f48146b0b094705dc48af5a1f
ToppCell	Frontal_cortex-Macroglia-POLYDENDROCYTE-P4-Tnr-Polydendrocyte.Tnr.Dlx1_(Dlx1)\|Frontal_cortex / BrainAtlas - Mouse McCarroll V32	NUF2 TTK ASPM DDX43 DNAH11	2.62e-05	142	109	5	92bf826827b3e3387ad326566556fc90c5c2f4d5
ToppCell	COVID-19-Epithelial_cells-Airway_mucous\|COVID-19 / group, cell type (main and fine annotations)	DSP CCDC148 CFAP54 CFAP46 DNAH11	3.51e-05	151	109	5	8216462e723fec2797387929dde095370947e10a
ToppCell	E16.5-Immune-Immune_Myeloid-Granulocytic-Neutrophil-Neutrophil_mature\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	IL16 TTC39C PYGL C3 TNFAIP8	3.74e-05	153	109	5	6a2a2379238133ce0ad714af130ffe02dd317247
ToppCell	E16.5-Immune-Immune_Myeloid-Granulocytic-Neutrophil\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	IL16 TTC39C PYGL C3 TNFAIP8	3.74e-05	153	109	5	faa442dd925b2b09919e93c492ccc3f19803ad24
ToppCell	LPS-IL1RA+antiTNF-Epithelial_airway-Ciliated_cells\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	SLC9C2 CCDC148 CFAP54 CFAP46 DNAH11	3.98e-05	155	109	5	5f1e2195a6b831e1b636f5cc3a282ca423721822
ToppCell	LPS-IL1RA+antiTNF-Epithelial_airway-Ciliated_cells-Ciliated\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	SLC9C2 CCDC148 CFAP54 CFAP46 DNAH11	3.98e-05	155	109	5	0944429459f642a1bcc56edc1ec28aaecde3e2dc
ToppCell	TCGA-Kidney-Primary_Tumor-Renal_Cell_Carcinoma-Kidney_Clear_Cell_Renal_Carcinoma-6\|TCGA-Kidney / Sample_Type by Project: Shred V9	KIF18A NUF2 TTK ASPM MAGEC2	4.11e-05	156	109	5	d249747c7108a0edfc72d24c09b0b0e4ed662b40
ToppCell	TCGA-Brain-Primary_Tumor-Low_Grade_Glioma-Oligoastrocytoma\|TCGA-Brain / Sample_Type by Project: Shred V9	KIFBP VPS13D TAOK3 MDN1 RBM17	4.77e-05	161	109	5	347edb0de10850b7d16c40945751033289289c9b
ToppCell	LPS-antiTNF-Epithelial_airway-Mes-Epi-like\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	KIF18A NUF2 TTK SCN1A ASPM	5.21e-05	164	109	5	4307b002fb41ddfc7ab8a6bca66a60942c250052
ToppCell	LPS-antiTNF-Epithelial_airway-Mes-Epi-like-Airway\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	KIF18A NUF2 TTK SCN1A ASPM	5.21e-05	164	109	5	1d84aa5b925f502ee9c5fa39714490f613a58028
ToppCell	PND10-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_T-CD4_T-CD4_T_G2M\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	KIF18A POLH TRMT2B ASPM ARHGAP19	5.52e-05	166	109	5	a41a20cef053c67da2d435e3e132ce28f1661c03
ToppCell	Dividing_Macrophages-Cryobiopsy_01\|World / lung cells shred on cell class, cell subclass, sample id	KIF18A ARHGEF28 NUF2 TTK ASPM	5.52e-05	166	109	5	c503036f3c19ef186e1e62c9643c49dea3827f51
ToppCell	Ciliated_cells-B-Donor_08\|World / lung cells shred on cell class, cell subclass, sample id	CERKL SLC9C2 CFAP54 C19orf44 DNAH11	5.52e-05	166	109	5	4b1056aad8a99827835242b8ab0c7f2bb84471f1
ToppCell	Control-B_cells-Activated_B_cells\|Control / group, cell type (main and fine annotations)	INPP5D PRDM2 RASSF6 RASGRP3 TNFAIP8	5.84e-05	168	109	5	a7159a35fe37f8c241cf8d391debe271e0698105
ToppCell	PND01-Immune-Immune_Myeloid-Monocytic-Macrophage-AM-AM_G2M\|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	KIF18A NUF2 TTK ASPM ARHGAP19	5.84e-05	168	109	5	52fd65024af8683db11d931f7563cbe8eb815d1c
ToppCell	saliva-Severe-critical_progression_d28-40-Lymphocytic-Lymphocytic_B-B_cell-B_c01-TCL1A\|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)	CERKL TSGA10 POTEI CFAP46 DNAH11	5.84e-05	168	109	5	9a8709d34865cfa668d8f3335dc34fc86fc32482
ToppCell	droplet-Large_Intestine-COLON_PROXIMAL-30m-Epithelial-Lgr5+_amplifying_undifferentiated_cell\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ARHGEF28 CCDC122 PYGB AKAP1 DNAH11	5.84e-05	168	109	5	d69452e2cfeb74023b5cf3d09064d7dcad0008ec
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_G2M\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	KIF18A POLH NUF2 TTK ASPM	6.01e-05	169	109	5	b253a4a50c06d36228fcd5d856c57202cbac158f
ToppCell	3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.0.2\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CCDC148 CFAP54 ANKRD18A CFAP46 DNAH11	6.01e-05	169	109	5	14aadc2d1bf66eb47dac33b4d61ddb3c942caa4f
ToppCell	PND07-Immune-Immune_Myeloid-Monocytic-Macrophage-AM-AM_G2M\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	DNAJC13 NUF2 ASPM PYGL DDX43	6.35e-05	171	109	5	845f312f8cbe29d820da25f0e6d75deb382bbfd8
ToppCell	facs-Marrow-T-cells-3m-Myeloid-granulocytopoietic_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	APAF1 NUF2 TTK C3 ARHGAP19	6.35e-05	171	109	5	913bae728b5e653771a27c79a309eb023699f1d0
ToppCell	facs-Marrow-T-cells-3m-Myeloid-granulocytopoietic_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	APAF1 NUF2 TTK C3 ARHGAP19	6.35e-05	171	109	5	f28b2336057e353b96a6ff4581ec9fd0ca0789d9
ToppCell	PBMC_fresh-frozen-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c12-FOXP3\|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)	TTC39C HSPBP1 RPL39L ANKRD36B ASPM	6.53e-05	172	109	5	eee45759284baa3ed77da6a5fbcc4f8f6c553106
ToppCell	390C-Myeloid-Dendritic-cDC_proliferating_1\|Myeloid / Donor, Lineage, Cell class and subclass (all cells)	KIF18A NUF2 TTK ASPM ARHGAP19	6.53e-05	172	109	5	6fcc16f1067672967ecbcdfdc727649ae9891dd9
ToppCell	5'-Airway_Nasal-Epithelial-Epithelial_transtional-secretory-club_cell-Club_(nasal)-Club_(nasal)_L.0.2.1.2\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	DSP NUF2 RPL39L TTK ASPM	7.08e-05	175	109	5	9142ed8ca2f1c0c518deb21988221406f62fe38c
ToppCell	PND10-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-Pericyte-Pericyte_G2M\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	KIF18A NUF2 TTK RASSF6 ASPM	7.08e-05	175	109	5	15c69dd5635c9251c535f1e22467712e9667ae92
ToppCell	PND10-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_T-Treg-Treg_G2M\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	NUF2 RPL39L TTK PYHIN1 ASPM	7.08e-05	175	109	5	9de288c338cee67be0e9b836c87799bbc1db1c38
ToppCell	368C-Epithelial_cells-Epithelial-B_(AT2)-\|368C / Donor, Lineage, Cell class and subclass (all cells)	DSP GPD1L SCN1A CCDC191 RAPGEFL1	7.47e-05	177	109	5	ac8f774596068e66c0a9ea8a318be0ce5f5df834
ToppCell	(01)_Cycling_Basal_(homeostasis)\|World / shred by cell type and Timepoint	KIF18A NUF2 TTK ASPM ARHGAP19	7.47e-05	177	109	5	05c57578142a6662f18b294d5cc11e6efd6b0f8e
ToppCell	TCGA-Brain-Primary_Tumor-Low_Grade_Glioma\|TCGA-Brain / Sample_Type by Project: Shred V9	KIFBP SPTAN1 VPS13D MDN1 RBM17	7.47e-05	177	109	5	e8ab340b20cd41554c3841fe980e078e878af35f
ToppCell	368C-Epithelial_cells-Epithelial-B_(AT2)\|368C / Donor, Lineage, Cell class and subclass (all cells)	DSP GPD1L SCN1A CCDC191 RAPGEFL1	7.47e-05	177	109	5	d9c4a93b0e04a13bf39992dd1c1ec8df2c5f89fe
ToppCell	Fetal_29-31_weeks-Epithelial-ciliated_cell-D062\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	CERKL SLC9C2 CFAP54 CFAP46 DNAH11	7.68e-05	178	109	5	de5d50d7ca9ee9eb62f50c88a0c6d47f0694b2e6
ToppCell	control-Lymphoid-NKT-proliferating\|control / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	RPL34 NUF2 RPL39L TTK ASPM	8.09e-05	180	109	5	535535a67b3f3320bad2f98b1bc98a7b0ee77840
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell_cycling\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	KIF18A NUF2 TTK SCN2A ASPM	8.09e-05	180	109	5	401df9cddcbca1eb8f0d2687bcacd98e95dc1493
ToppCell	LPS-IL1RA-Endothelial-Endothelial-FOXM1\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	KIF18A NUF2 TTK ASPM ARHGAP19	8.09e-05	180	109	5	334e2b1f6eb7d4ece20b1c7b02107863f913237f
ToppCell	Fetal_29-31_weeks-Epithelial-ciliated_cell-D088\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	CERKL SLC9C2 CFAP54 CFAP46 DNAH11	8.30e-05	181	109	5	dfce05bd472f67e6e2bb60ebd6fd34f0a9aeeca6
ToppCell	10x5'-Liver-Lymphocytic_T_CD4-T_CD4/CD8\|Liver / Manually curated celltypes from each tissue	TTC39C SPTAN1 ANKRD36C ANKRD36B ANKRD36	8.30e-05	181	109	5	f2315414e714ac86211546a935660c4be6e85f1b
ToppCell	Control-Epithelial_alveolar-AT_1-AT1-AT2\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	DSP RASSF6 MYO3B C3 MME	8.52e-05	182	109	5	a95956ce4adccb34cc0c47ebfa1878ce4617904e
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell_cycling-Cycling_Connecting_Tubule_Cell_G2M\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	KIF18A POLH NUF2 TTK ASPM	8.52e-05	182	109	5	336cd05e46a741185ce3c59ee67a4b07fa6a5101
ToppCell	Control-Epithelial_cells-Airway_ciliated\|Control / group, cell type (main and fine annotations)	SLC9C2 CCDC148 CFAP54 CFAP46 DNAH11	8.52e-05	182	109	5	fb725d10d9ed25dfc6d5bb69cfef78513f7d3e8f
ToppCell	PCW_05-06-Epithelial-Epithelial_airway-epi_proximal_progenitor1_(6)\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	ARHGEF28 KREMEN1 DSP RASSF6 MTTP	8.75e-05	183	109	5	c5b10571599dc26476170b54b53f09c23e6b3117
ToppCell	Control-Epithelial_alveolar-AT_2\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ARHGEF28 DSP GPD1L C3 MME	8.97e-05	184	109	5	51e129b3fcc2df083eda05a3afe3717218b1e52b
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Macula_Densa_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	MYH10 CCDC148 SLC12A1 MYO3B PYGB	8.97e-05	184	109	5	d33de57876817050b294f2ecb0a4eb0634cfa7f0
ToppCell	Children_(3_yrs)-Epithelial-ciliated_cell-D139\|Children_(3_yrs) / Lineage, Cell type, age group and donor	CERKL SLC9C2 CFAP54 CFAP46 DNAH11	8.97e-05	184	109	5	5daff849625f2f41d56615569c0ed59cd733b34c
ToppCell	3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-bronchial_goblet_cell-Goblet_(bronchial)-Goblet_(bronchial)_L.0.4.2.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ANKRD36C ANKRD36B C3 ANKRD18A ANKRD36	8.97e-05	184	109	5	01c19a830348ab0b9c02c1546a439de70ee10f97
ToppCell	PND10-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_B-B-B_G2M\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	KIF18A NUF2 TTK ASPM ARHGAP19	8.97e-05	184	109	5	8f40093de5bb978f046d66e8f05f333686a009a4
ToppCell	Control-Epithelial_alveolar-AT_2-AT2_Progenitor\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ARHGEF28 DSP GPD1L C3 MME	9.20e-05	185	109	5	8ca1374501eca01d8468130b74d50abfd4329fbe
ToppCell	COVID-cycling-\|COVID / Condition, Cell_class and T cell subcluster	KIF18A NUF2 RPL39L TTK ASPM	9.20e-05	185	109	5	eb74b8d36f7b749e04bc2ed4b36f7e1ac7bb6d5f
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_G2M\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	KIF18A POLH NUF2 TTK ASPM	9.20e-05	185	109	5	30e041d6f6e310d64809e9d6d93cd30052972f3b
ToppCell	COVID-cycling\|COVID / Condition, Cell_class and T cell subcluster	KIF18A NUF2 RPL39L TTK ASPM	9.20e-05	185	109	5	5112f966735fa48f0606adcfd5c0212ad5d3d77a
ToppCell	tumor_Lung-B_lymphocytes\|tumor_Lung / Location, Cell class and cell subclass	IL16 INPP5D PRDM2 RASSF6 RASGRP3	9.44e-05	186	109	5	a54b368d7921185c583e35b532a6898c5486c2fc
ToppCell	facs-Skin-Telogen-3m-Epithelial-actively_dividing_stem_cell\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KIF18A NUF2 TTK ASPM ARHGAP19	9.44e-05	186	109	5	9feef5936985e936b3d88f9d1bb012abb6468570
ToppCell	NS-critical-d_16-33-Epithelial-Ciliated\|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	CERKL CFAP54 ANKRD18A CFAP46 DNAH11	9.44e-05	186	109	5	76033438426d8f9c72cd6691a7baf92104c9f03d
ToppCell	356C-Lymphocytic-CD4_T-cell-Proliferating_T_cell\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	MYH10 NUF2 ASPM PYGL PRKG2	9.44e-05	186	109	5	722da08cd978249a19855fd3ec8ddda780c99d83
ToppCell	facs-Skin-Telogen-3m-Epithelial-keratinocyte_stem_cell\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KIF18A NUF2 TTK ASPM ARHGAP19	9.44e-05	186	109	5	89f5b06bc56674af304912d481ac697c7c870904
ToppCell	Fetal_29-31_weeks-Epithelial-ciliated_cell\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	CERKL SLC9C2 CFAP54 CFAP46 DNAH11	9.68e-05	187	109	5	9e10ed56090d82589bc457788282f664b70ace4b
ToppCell	COVID-19-kidney\|COVID-19 / Disease (COVID-19 only), tissue and cell type	ARHGEF28 CCDC148 SLC12A1 SCN2A MYO3B	9.68e-05	187	109	5	d23aae9419d460b78b1d4092d7acd9108a47cfbe
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	KIF18A POLH NUF2 TTK ASPM	9.68e-05	187	109	5	9351fa87b69a951af85b10bf91fe9b1cce8c0517
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell_cycling\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	KIF18A POLH NUF2 TTK ASPM	9.68e-05	187	109	5	057569c9437219ecc396aa6e673b1178a2273837
ToppCell	Epithelial-ciliated_cell\|World / Lineage, Cell type, age group and donor	CERKL SLC9C2 CFAP54 CFAP46 DNAH11	9.93e-05	188	109	5	61a459f3fe57e5728efc72637ff2edc2d343492b
Drug	diazinon	POTED TTK POTEC PYGB PYGL MME DNAH11	3.79e-07	98	106	7	CID000003017
Drug	DIBAH	SLC12A1 PYGB PYGL	5.40e-06	8	106	3	CID000014487
Drug	NSC611747	MYH10 GSK3B PPP1R7 SLC12A1 SCN2A MYO3B PYGB PYGL PRKG2 AKAP1	5.87e-06	352	106	10	CID000002534
Drug	Phytoestrogens	NUF2 TTK GSK3B ASPM IL6	1.53e-05	67	106	5	ctd:D048789
Drug	glycogen phosphorylase inhibitor	GSK3B PYGB PYGL	1.58e-05	11	106	3	CID010070301
Drug	5-(2-chloroethyl)uracil	PYGB PYGL	2.15e-05	2	106	2	CID010442204
Drug	6878P	PYGB PYGL	2.15e-05	2	106	2	CID002725013
Drug	AC1LBRFU	PYGB PYGL	2.15e-05	2	106	2	CID000562981
Drug	Gvapspat amide	PYGB PYGL PRKG2	4.28e-05	15	106	3	CID000125015
Drug	BeSO4	MSH2 PYGB PYGL	4.28e-05	15	106	3	CID000026077
Drug	sulfonamide analog 1	UGGT1 GSK3B PPP1R7 PYGB PYGL AKAP1 IL6	6.33e-05	213	106	7	CID005327336
Drug	3,5-dimethylphenyl isocyanate	PYGB PYGL	6.42e-05	3	106	2	CID000521488
Drug	5'-deoxy-5'-fluoro-5'-(methylthio)adenosine	PYGB PYGL	6.42e-05	3	106	2	CID000147839
Drug	NSC758405	PYGB PYGL	6.42e-05	3	106	2	CID000003201
Drug	3,5-dinitrophenyl phosphate	PYGB PYGL	6.42e-05	3	106	2	CID000151920
Drug	pyridoxal phosphoglucose	PYGB PYGL	6.42e-05	3	106	2	CID000196007
Drug	Aspaminol	PYGB PYGL	6.42e-05	3	106	2	CID003084278
Drug	5-ethyl-4-hydroxy-2-methyl-3(2H)-furanone	PYGB PYGL	6.42e-05	3	106	2	CID000093111
Drug	adenosine-5'-chloromethylphosphonate	PYGB PYGL	6.42e-05	3	106	2	CID000191554
Drug	hydan	PYGB PYGL	6.42e-05	3	106	2	CID000008360
Drug	EHMF	PYGB PYGL	6.42e-05	3	106	2	CID000033931
Drug	AC1L29EX	PYGB PYGL	6.42e-05	3	106	2	CID000043221
Drug	pyridoxal 5'-methylenephosphonate	PYGB PYGL	6.42e-05	3	106	2	CID003082249
Drug	Plp 5'-mpa	PYGB PYGL	6.42e-05	3	106	2	CID003082151
Drug	glucose-1,2-cyclic phosphate	PYGB PYGL	6.42e-05	3	106	2	CID000191723
Drug	3'-FFdUrd	PYGB PYGL	6.42e-05	3	106	2	CID000072260
Drug	2',3',4',5,5'-pentachloro-2-biphenylol	PYGB PYGL	6.42e-05	3	106	2	CID000119518
Drug	AC1L8XK3	PYGB PYGL	6.42e-05	3	106	2	CID000409735
Drug	N-acetyl-N'-beta-D-glucopyranosyl urea	PYGB PYGL	6.42e-05	3	106	2	CID000446801
Drug	riboflavin tetraacetate	PYGB PYGL	6.42e-05	3	106	2	CID000094186
Drug	2,5-dimethyl-3-furanone	PYGB PYGL	6.42e-05	3	106	2	CID000085730
Drug	3,5-dinitrophenol	PYGB PYGL	6.42e-05	3	106	2	CID000011459
Drug	2-amino-6-chloropurine	SLC12A1 PYGB PYGL	7.61e-05	18	106	3	CID005360349
Drug	2-hydroxyursolic acid	PYGB PYGL TNFAIP8	7.61e-05	18	106	3	CID000155934
Drug	octaethylporphyrin	DSP SCN2A MTTP	9.00e-05	19	106	3	CID000102311
Drug	A-443654	GSK3B PYGB PYGL	1.06e-04	20	106	3	CID010172943
Drug	diphenyl phosphonate	PYGB PYGL MME	1.23e-04	21	106	3	CID006327546
Drug	galocitabine	PYGB PYGL	1.28e-04	4	106	2	CID000065950
Drug	5-deoxyribose-1-phosphate	PYGB PYGL	1.28e-04	4	106	2	CID000135786
Drug	ingliforib	PYGB PYGL	1.28e-04	4	106	2	CID006451325
Drug	uric acid riboside	PYGB PYGL	1.28e-04	4	106	2	CID000164933
Drug	pseudo-dl-glucose	PYGB PYGL	1.28e-04	4	106	2	CID000125259
Drug	pyridoxal diphosphate	PYGB PYGL	1.28e-04	4	106	2	CID000125696
Drug	2,5-anhydro-D-mannitol 1-phosphate	PYGB PYGL	1.28e-04	4	106	2	CID000189134
Drug	AC1LAMW2	PYGB PYGL	1.28e-04	4	106	2	CID000491364
Drug	FdUrd-C8	PYGB PYGL	1.28e-04	4	106	2	CID000094262
Drug	Mem-CC	PYGB PYGL	1.28e-04	4	106	2	CID003081269
Drug	2H-5a	PYGB PYGL	1.28e-04	4	106	2	CID000440102
Drug	BCIp4A	PYGB PYGL	1.28e-04	4	106	2	CID000192417
Drug	bredinin	GSK3B C3	1.28e-04	4	106	2	ctd:C010052
Drug	3'-chloromethotrexate	PYGB PYGL	1.28e-04	4	106	2	CID000097703
Drug	8-prenylnaringenin	KIF18A C3 IL6	1.42e-04	22	106	3	ctd:C119737
Drug	2-deoxyinosine	KIFBP APAF1 PYGB PYGL	1.77e-04	60	106	4	CID000000639
Drug	C12063	CERKL HCN1 UGGT1 APAF1 SLC12A1 SCN2A ASNS IL6 CHMP1A	1.80e-04	429	106	9	CID005282055
Drug	BrVarafUTP	POLH PYGB PYGL	1.85e-04	24	106	3	CID005273539
Drug	Azaguanine-8 [134-58-7]; Down 200; 26.2uM; PC3; HT_HG-U133A	KIF18A TTK ASPM TTI1 AKAP1 ARHGAP19	2.05e-04	181	106	6	1791_DN
Drug	hexylamine	ASNS PYGB PYGL	2.09e-04	25	106	3	CID000008102
Drug	heptulose-2-P	PYGB PYGL	2.13e-04	5	106	2	CID000124823
Drug	6-FPLP	PYGB PYGL	2.13e-04	5	106	2	CID000146246
Drug	gluconohydroximo-1,5-lactone	PYGB PYGL	2.13e-04	5	106	2	CID009576855
Drug	DHPBU	PYGB PYGL	2.13e-04	5	106	2	CID000125914
Drug	5'-isobutylthioinosine	PYGB PYGL	2.13e-04	5	106	2	CID003080910
Drug	indirubin-5-sulphonate	PYGB PYGL	2.13e-04	5	106	2	CID005288641
Drug	VaraU	PYGB PYGL	2.13e-04	5	106	2	CID000126501
Drug	AC1LCUXJ	PYGB PYGL	2.13e-04	5	106	2	CID000656425
Drug	6-amino-5-bromouracil	PYGB PYGL	2.13e-04	5	106	2	CID000080578
Drug	etafenone	PYGB PYGL	2.13e-04	5	106	2	CID000003275
Drug	ddEtUrd	PYGB PYGL	2.13e-04	5	106	2	CID000451452
Drug	5-trifluoromethyl-2'-deoxycytidine	PYGB PYGL	2.13e-04	5	106	2	CID000125618
Drug	BrdAdo	PYGB PYGL	2.13e-04	5	106	2	CID000055914
Drug	m-anisidine	PYGB PYGL	2.13e-04	5	106	2	CID000010824
Drug	Gold Sodium Thiosulfate	TLR3 IL6	2.13e-04	5	106	2	ctd:D012971
Drug	2-hydroxypropylphosphonate	PYGB PYGL	2.13e-04	5	106	2	CID000441028
Drug	6-FDPL	PYGB PYGL	2.13e-04	5	106	2	CID000129578
Drug	3'-O-methylpyridoxal 5'-phosphate	PYGB PYGL	2.13e-04	5	106	2	CID003082179
Drug	GlcMan	PYGB PYGL	2.13e-04	5	106	2	CID000152120
Drug	U66985	PYGB PYGL	2.13e-04	5	106	2	CID000127224
Drug	AC1O3M08	PYGB PYGL	2.13e-04	5	106	2	CID006331955
Drug	Apigenin [520-36-5]; Down 200; 14.8uM; HL60; HT_HG-U133A	APAF1 MSH2 TRMT2B FRMD4B TNFAIP8 AKAP1	2.24e-04	184	106	6	1321_DN
Drug	glycine ethyl ester	SCN2A PYGB PYGL	2.36e-04	26	106	3	CID000012175
Drug	a-sophorose	SCN2A PYGB PYGL	2.64e-04	27	106	3	CID000088719
Drug	Riboflavin	GSK3B RASGRP3 ASPM IL6	2.72e-04	67	106	4	ctd:D012256
Drug	Resveratrol [501-36-0]; Down 200; 17.6uM; HL60; HG-U133A	SRP72 HSPBP1 TTK VPS13D ASPM ARHGAP19	2.98e-04	194	106	6	1715_DN
Drug	0316684-0000 [391209-55-5]; Down 200; 10uM; PC3; HT_HG-U133A	ARHGEF28 POLH CC2D1A HDAC7 PTCD2 IL6	3.15e-04	196	106	6	7057_DN
Drug	norstatine	PYGB PYGL	3.18e-04	6	106	2	CID000173844
Drug	CV-araU	PYGB PYGL	3.18e-04	6	106	2	CID006441877
Drug	2-thiothymidine	PYGB PYGL	3.18e-04	6	106	2	CID003005944
Drug	Carbocyclic Bvdc	PYGB PYGL	3.18e-04	6	106	2	CID006438602
Drug	AC1NDJ6Q	PYGB PYGL	3.18e-04	6	106	2	CID004602095
Drug	2,2-dimethyl-3-hydroxybutyric acid	PYGB PYGL	3.18e-04	6	106	2	CID000152984
Drug	EdUMP	PYGB PYGL	3.18e-04	6	106	2	CID003085112
Drug	5'-deoxy-5'-chloroformycin	PYGB PYGL	3.18e-04	6	106	2	CID000126430
Drug	5-n-propylthioadenosine	PYGB PYGL	3.18e-04	6	106	2	CID000656428
Drug	AzddCyd	PYGB PYGL	3.18e-04	6	106	2	CID000451374
Drug	5-Ffdru	PYGB PYGL	3.18e-04	6	106	2	CID000065561
Drug	Carbocyclic Ivdu	PYGB PYGL	3.18e-04	6	106	2	CID006439191
Drug	DNPP	PYGB PYGL	3.18e-04	6	106	2	CID000067056
Drug	5-chloro-indole-2-carboxylic acid	PYGB PYGL	3.18e-04	6	106	2	CID000082693
Drug	NSC-97433	PYGB PYGL	3.18e-04	6	106	2	CID000001803
Drug	BAY R3401	PYGB PYGL	3.18e-04	6	106	2	CID009842599
Disease	Generalized Epilepsy with Febrile Seizures Plus	HCN1 SCN1A SCN2A	2.59e-06	9	94	3	C3502809
Disease	Epilepsy	HCN1 DYRK1A SCN1A SCN2A KCNH5	2.65e-05	109	94	5	C0014544
Disease	anxiety disorder (implicated_via_orthology)	HCN1 SCN1A SCN2A	4.61e-05	22	94	3	DOID:2030 (implicated_via_orthology)
Disease	polychlorinated biphenyls measurement	HCN1 RPL39P5 RASGRP3 PYGL	5.63e-05	65	94	4	EFO_0007042
Disease	lactic acidosis (implicated_via_orthology)	PYGL TRMT5	9.98e-05	5	94	2	DOID:3650 (implicated_via_orthology)
Disease	Epilepsy, Cryptogenic	HCN1 DYRK1A SCN1A SCN2A	1.40e-04	82	94	4	C0086237
Disease	Awakening Epilepsy	HCN1 DYRK1A SCN1A SCN2A	1.40e-04	82	94	4	C0751111
Disease	Aura	HCN1 DYRK1A SCN1A SCN2A	1.40e-04	82	94	4	C0236018
Disease	EPILEPTIC ENCEPHALOPATHY, EARLY INFANTILE, 1	HCN1 SCN1A	1.49e-04	6	94	2	C3463992
Disease	Seizure, Febrile, Simple	SCN1A SCN2A	2.09e-04	7	94	2	C0149886
Disease	Seizure, Febrile, Complex	SCN1A SCN2A	2.09e-04	7	94	2	C0751057
Disease	X-linked infantile spasms	HCN1 SCN1A	2.78e-04	8	94	2	C4552072
Disease	Febrile Convulsions	SCN1A SCN2A	3.56e-04	9	94	2	C0009952
Disease	neutrophil count	DNAJC13 TTC39C INPP5D DYRK1A NUF2 NSMCE2 GSK3B IQSEC1 PTCD2 TNFAIP8 R3HDM1 ARHGAP19 RAPGEFL1	4.35e-04	1382	94	13	EFO_0004833
Disease	generalized epilepsy with febrile seizures plus 2 (implicated_via_orthology)	SCN1A SCN2A	4.44e-04	10	94	2	DOID:0111294 (implicated_via_orthology)
Disease	Dravet syndrome (implicated_via_orthology)	SCN1A SCN2A	4.44e-04	10	94	2	DOID:0080422 (implicated_via_orthology)
Disease	Hemolytic-Uremic Syndrome	C3 IL6	5.42e-04	11	94	2	C0019061
Disease	hyperinsulinism (is_implicated_in)	MTTP IL6	6.49e-04	12	94	2	DOID:2018 (is_implicated_in)
Disease	generalized epilepsy with febrile seizures plus (implicated_via_orthology)	SCN1A SCN2A	6.49e-04	12	94	2	DOID:0060170 (implicated_via_orthology)
Disease	asthma (is_marker_for)	IL16 TLR3 C3 IL6	7.18e-04	126	94	4	DOID:2841 (is_marker_for)
Disease	Infantile Severe Myoclonic Epilepsy	SCN1A SCN2A	7.65e-04	13	94	2	C0751122
Disease	Congenital pontocerebellar hypoplasia	VPS53 CHMP1A	7.65e-04	13	94	2	C0266468
Disease	Alzheimer's disease (implicated_via_orthology)	GSK3B MME IL6	8.09e-04	57	94	3	DOID:10652 (implicated_via_orthology)
Disease	Kuhnt-Junius degeneration (is_marker_for)	TLR3 IL6	8.91e-04	14	94	2	DOID:10873 (is_marker_for)
Disease	Down syndrome (implicated_via_orthology)	DYRK1A DYRK1B	1.03e-03	15	94	2	DOID:14250 (implicated_via_orthology)
Disease	MMR-related febrile seizures	SCN1A SCN2A	1.03e-03	15	94	2	EFO_0006519
Disease	stomach cancer (is_marker_for)	KIF18A NUF2 ASPM IL6	1.12e-03	142	94	4	DOID:10534 (is_marker_for)
Disease	syndromic intellectual disability (implicated_via_orthology)	DYRK1A DYRK1B	1.17e-03	16	94	2	DOID:0050888 (implicated_via_orthology)
Disease	anthranilic acid measurement	NSMCE2 MYO3B	1.17e-03	16	94	2	EFO_0010460
Disease	autism spectrum disorder (is_implicated_in)	DYRK1A CYFIP1	1.17e-03	16	94	2	DOID:0060041 (is_implicated_in)
Disease	Pontoneocerebellar hypoplasia	VPS53 CHMP1A	1.17e-03	16	94	2	cv:C1261175
Disease	Early infantile epileptic encephalopathy with suppression bursts	SCN1A SCN2A	1.17e-03	16	94	2	C0393706
Disease	Liver carcinoma	KIF18A NUF2 TTK ASPM PYGL MAGEC2 IL6	1.20e-03	507	94	7	C2239176
Disease	pre-eclampsia (biomarker_via_orthology)	TLR3 IL6	1.32e-03	17	94	2	DOID:10591 (biomarker_via_orthology)
Disease	perinatal necrotizing enterocolitis (biomarker_via_orthology)	TLR3 IL6	1.32e-03	17	94	2	DOID:8677 (biomarker_via_orthology)
Disease	autism spectrum disorder (implicated_via_orthology)	DYRK1A TAOK3 SCN1A SCN2A	1.44e-03	152	94	4	DOID:0060041 (implicated_via_orthology)
Disease	Febrile seizure (within the age range of 3 months to 6 years)	SCN1A SCN2A	1.49e-03	18	94	2	HP_0002373
Disease	non-alcoholic fatty liver disease (is_implicated_in)	MTTP IL6	1.49e-03	18	94	2	DOID:0080208 (is_implicated_in)
Disease	temporal lobe epilepsy (is_marker_for)	HCN1 CYFIP1	1.84e-03	20	94	2	DOID:3328 (is_marker_for)
Disease	alpha-tocopherol measurement	DYRK1A IL6	1.84e-03	20	94	2	EFO_0007898
Disease	epilepsy (implicated_via_orthology)	SLC12A1 SCN1A SCN2A KCNH5	1.86e-03	163	94	4	DOID:1826 (implicated_via_orthology)
Disease	Lung Injury	MME IL6	2.03e-03	21	94	2	C0273115
Disease	Chronic Lung Injury	MME IL6	2.03e-03	21	94	2	C2350344
Disease	lung non-small cell carcinoma (is_marker_for)	APAF1 MSH2 NUF2 IQSEC1	2.12e-03	169	94	4	DOID:3908 (is_marker_for)
Disease	prostate carcinoma	NUF2 TTK PPP1R7 RASSF6 PYGB ANKRD36 VPS53 IL6 DNAH11	2.16e-03	891	94	9	EFO_0001663
Disease	West Syndrome	SPTAN1 SCN2A	2.65e-03	24	94	2	C0037769
Disease	anogenital venereal wart (is_marker_for)	TLR3 IL6	3.10e-03	26	94	2	DOID:11168 (is_marker_for)

Protein segments in the cluster

Peptide	Gene	Start	Entry
KLVNAIQQKLSKLKG	APAF1	131	O14727
VKNNLRILFNNAVKK	ASNS	231	P08243
KKLQFSLKKLGVNNI	BTF3	86	P20290
KALNLIGKKFKELNL	AKAP1	666	Q92667
AKIAQFIKSLNVEKK	CFAP54	2001	Q96N23
NKNKKDFIQKAVLTL	CCDC148	326	Q8NFR7
ILFKKLKQKFNDLVA	ANKRD18A	741	Q8IVF6
HKKVNKSKVTINIQF	ANKRD30B	1321	Q9BXX2
IQQLKFSQIVNLKGK	CPSF2	126	Q9P2I0
KQKFTRAVKKLNANI	ATG14	341	Q6ZNE5
IFQKLINAFKILKKE	CFAP46	1701	Q8IYW2
KLFAKHIKVQAQVKL	CMSS1	186	Q9BQ75
VAVDKGVFVLNKKNK	C3	596	P01024
GVFVLNKKNKLTQSK	C3	601	P01024
EQISLFKNLLKKKQN	DNAH11	3076	Q96DT5
SAQKVIFKKKVSLLN	ANKRD36	1231	A6QL64
QKVIFKKKVSLLNIA	ANKRD36B	331	Q8N2N9
QKVIFKKKVSLLNIA	ANKRD36B	671	Q8N2N9
AIKIIKNKKAFLNQA	DYRK1A	186	Q13627
LVAIKIIKNKKAFLN	DYRK1B	136	Q9Y463
IIKNKKAFLNQAQIE	DYRK1B	141	Q9Y463
KRKFQEIKNSTIKIQ	ASPM	2926	Q8IZT6
TFKIKQFLAKKQKQN	RPL39P5	6	Q59GN2
QNALKKQINSVNKFK	R3HDM1	1066	Q15032
DVKVALKKILNKNAF	OR8B8	296	Q15620
FNKEKAIILKCLQNK	RASSF6	346	Q6ZTQ3
VKFLIKKKANLNALD	POTEB2	251	H3BUK9
FQKAKNKEFLQEKTL	OXSR1	291	O95747
QQAFEKLILKVKKQL	LTN1	126	O94822
YIKIVINKKQLQLGK	NUB1	126	Q9Y5A7
KELQQNKKFQNFIKL	ARHGEF28	966	Q8N1W1
AQKVIFKKKVSLLNI	ANKRD36C	1096	Q5JPF3
FQLKFTAKQLEKLAK	CHMP1A	6	Q9HD42
LRQAIKKKKNVIQSV	CYFIP1	496	Q7L576
KKKKNVIQSVLQAIR	CYFIP1	501	Q7L576
QVVKFLIKKKANLNA	POTEF	286	A5A3E0
LRLCKFQQKKTKIAQ	MDN1	5451	Q9NU22
KKKVLEFLAKLNNTV	MAGEC2	311	Q9UBF1
AKIIGNNVKKLQKFA	GPD1L	21	Q8N335
NQNVIKKQNKDLKFV	KIF18A	61	Q8NI77
FNDLLVVTKIFQKKK	IQSEC1	781	Q6DN90
VRKLFQKFKQQKELR	KCNH5	706	Q8NCM2
KQIQKAIIKVLIQKH	OR51F2	311	Q8NH61
IVKKEKLATAQFKIN	NUF2	346	Q9BZD4
NFLQTIKGKIVSKQK	MTTP	241	P55157
QDALQKFKQAKKGLL	IL16	281	Q14005
IIQNLKFSQSKQLKK	MME	511	P08473
KLLVEKKFLALQSKN	NSMCE2	101	Q96MF7
FVQFKQQLKELKKQC	NSMCE2	126	Q96MF7
ISIFKKKLKGQSQQD	KREMEN1	451	Q96MU8
DKIFNKVEKIKQNAL	NSUN6	266	Q8TEA1
KKLITDALNKNQFLK	PRKG2	156	Q13237
QVVKFLIKKKANLNA	POTEB3	286	A0JP26
QVVKFLIKKKANLNA	POTEE	286	Q6S8J3
NFLIQQKLVEAAKKL	FRMD4B	506	Q9Y2L6
KKNSILLQKFQKDLN	HCN1	596	O60741
IEKNKKVLFNLKNEL	CCDC122	41	Q5T0U0
QNAKVSRFLKKKQAP	C19orf44	166	Q9H6X5
YKRQVQNLVNKSKKI	DSP	431	P15924
HVFQQQLIEKQKKKL	CCDC191	556	Q8NCU4
HVKVLNINLKRKFIK	PYHIN1	251	Q6K0P9
LVAIKKVLQDKRFKN	GSK3B	81	P49841
KKQLLQAALRAKQKN	CC2D1A	501	Q6P1N0
TLFICLKKEQNKLKN	CERKL	121	Q49MI3
FLNKLILNKKNVKDL	DNAJC13	916	O75165
KQKLAEVILKKQQAA	HDAC7	86	Q8WUI4
LKKLFLVNNKISKIE	PPP1R7	166	Q15435
IKLKQLKAEVIAKNN	MSH2	906	P43246
QTKAKAVIDNFVKKL	DDX43	121	Q9NXZ2
HIVKKINNLNKSALK	KIFBP	501	Q96EK5
FAKKQQQLSALKVLQ	MYH10	806	P35580
STKVLIQFLQKKAKN	IL6	146	P05231
ALKKKNQLVQKAILQ	PRDM2	1421	Q13029
NVVKLKEFQQKKVAV	PTCD2	51	Q8WV60
QVVKFLIKKKANLNA	POTEC	286	B2RU33
KIVVKVLKAQAQSQK	RPL34	101	P49207
QVVKFLIKKKANLNV	POTED	286	Q86YR6
QQVQKLKVKSAFLLQ	HSPBP1	241	Q9NZL4
KVKFAAQKKILQRLE	TRMT2B	101	Q96GJ1
KLNKVDQKVKVFNLD	TRMT5	341	Q32P41
TFTIKRFLAKKQKQN	RPL39L	6	Q96EH5
VKFLIKKKANLNALD	POTEB	251	A0A0A6YYL3
INVAKKLLQLKNFNT	RASGRP3	226	Q8IV61
QKQQVVKFLIKKKAN	POTEJ	246	P0CG39
VKFLIKKKANLNALD	POTEJ	251	P0CG39
HKKILQLIKSQKFLN	INPP5D	341	Q92835
FNQKLVEASTQFKKK	SLC12A1	891	Q13621
KKFQQQILAQQKKDL	TAOK3	531	Q9H2K8
QVVKFLIKKKANLNA	POTEI	286	P0CG38
VIKKLQNQVLLFKFL	VPS8	991	Q8N3P4
FFKQKSLLLKQKQLN	POLH	531	Q9Y253
FKLSKKQLQAIEFNK	SRP72	296	O76094
FNSKNLAVQAQKKIL	TNFAIP8	16	O95379
NKKTFIVLNKGKAIF	SCN1A	86	P35498
QKIKNNPFVKQKNLI	TLR3	136	O15455
FKKVALIQQLEKVLK	SAGE2P	581	A6NJ88
QFLVQKSAEKSQKLK	SPTAN1	1641	Q13813
KNFKLLQSQLQVKKA	RBM17	21	Q96I25
SFKALLIQAVKKAQK	TPRG1L	211	Q5T0D9
INKKTFIVLNKGKAI	SCN2A	86	Q99250
AKVKQENKLKFSAFL	PYGB	536	P11216
SAKKKQLIRQFNKQS	ARHGAP19	386	Q14CB8
QKAIQQLFGKIKDIK	VPS53	101	Q5VIR6
VEKLQNKLKVYKRQI	MYH16	1031	Q9H6N6
FAKAKQENQALSKKL	TSGA10	361	Q9BZW7
QGNVKKSKQLLQKAV	TTK	156	P33981
INKVLLKKLKALNNF	SLC9C2	836	Q5TAH2
FKEVQKLFKRKNNQI	TTC39C	411	Q8N584
LKKFIKIAALCKQNQ	RAPGEFL1	496	Q9UHV5
AKVKQENKLKFSQFL	PYGL	536	P06737
QVVKFLIKKKANLNA	POTEG	286	Q6S5H5
QVVKFLIKKKANLNA	POTEM	286	A6NI47
VLNNFKSKIIKVKVQ	UGGT1	1196	Q9NYU2
KSKQIKIAALKCLQV	TTI1	166	O43156
VANLGKLKVKNKFLF	VPS13D	2046	Q5THJ4
LFLQKQLAKVLQDQK	MYO3B	301	Q8WXR4