Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyBiologicalProcesssecretion by tissue

ENPP1 KCNMA1 WNK3 MADD

1.48e-0564484GO:0032941
MousePhenodecreased spongiotrophoblast size

RAF1 ERF SENP2

2.05e-0520383MP:0012099
MousePhenoabnormal spongiotrophoblast size

RAF1 ERF SENP2

5.79e-0528383MP:0012097
DomainCYCLINS

CCNT2 CCNB3

2.15e-0328462PS00292
DomainCyclin_N

CCNT2 CCNB3

2.98e-0333462IPR006671
DomainCyclin_N

CCNT2 CCNB3

2.98e-0333462PF00134
DomainCYCLIN

CCNT2 CCNB3

3.94e-0338462SM00385
Domain-

CCNT2 CCNB3

4.36e-03404621.10.472.10
DomainCyclin-like

CCNT2 CCNB3

5.03e-0343462IPR013763
Domainzf-C2H2_6

ZNF677 ZNF684 ZNF423 ZNF286A

7.34e-03314464PF13912
Pubmed

Lowered expression of microRNA-125a-5p in human hepatocellular carcinoma and up-regulation of its oncogenic targets sirtuin-7, matrix metalloproteinase-11, and c-Raf.

RAF1 SIRT7

1.16e-05449228445974
Pubmed

Endothelial RAF1/ERK activation regulates arterial morphogenesis.

RAF1 PECAM1

4.07e-05749223529931
Pubmed

Hdac4 Interactions in Huntington's Disease Viewed Through the Prism of Multiomics.

PITPNM2 THSD7A KCNMA1 TRMT1L MADD STAU1

5.35e-0547549631040226
Pubmed

c-Raf promotes angiogenesis during normal growth plate maturation.

RAF1 PECAM1

5.42e-05849226657770
Pubmed

Transcriptional repressor erf determines extraembryonic ectoderm differentiation.

ERF PECAM1

5.42e-05849217502352
Pubmed

C5orf51 is a component of the MON1-CCZ1 complex and controls RAB7A localization and stability during mitophagy.

ZFYVE16 NETO2 PIGS TRIM13 MADD STX12

7.41e-0550449634432599
Pubmed

The Ets2 Repressor Factor (Erf) Is Required for Effective Primitive and Definitive Hematopoiesis.

ERF PECAM1

1.06e-041149228694332
Pubmed

A protein-interaction network of interferon-stimulated genes extends the innate immune system landscape.

CUL5 RAF1 PIGS HAT1 ATP13A3 TRMT1L TRIM13 STX12 STAU1

1.60e-04144049930833792
Pubmed

Filamin C is Essential for mammalian myocardial integrity.

PECAM1 DAG1

1.75e-041449236706168
Pubmed

Deletion of astroglial connexins weakens the blood-brain barrier.

PECAM1 DAG1

1.75e-041449222472609
Pubmed

A protein interaction landscape of breast cancer.

RAF1 ETFB DAG1 TRMT1L STX12 STAU1

2.57e-0463449634591612
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

ZFYVE16 ZNF423 SENP2 ASAP1 MADD

2.67e-0440749512693553
Pubmed

The glomuvenous malformation protein Glomulin binds Rbx1 and regulates cullin RING ligase-mediated turnover of Fbw7.

CUL5 PECAM1

3.27e-041949222405651
Pubmed

New BRAF knockin mice provide a pathogenetic mechanism of developmental defects and a therapeutic approach in cardio-facio-cutaneous syndrome.

RAF1 PECAM1

4.01e-042149225035421
Pubmed

Report of the sixth international workshop on human chromosome 3 mapping 1995.

RAF1 DAG1

4.01e-04214928641130
Pubmed

Mice with megalencephalic leukoencephalopathy with cysts: a developmental angle.

PECAM1 DAG1

4.01e-042149225382142
Pubmed

BioID reveals an ATG9A interaction with ATG13-ATG101 in the degradation of p62/SQSTM1-ubiquitin clusters.

PPP1R21 TRAPPC11 ZFYVE16 STX12

7.00e-0428549434369648
Pubmed

ZFP423 regulates early patterning and multiciliogenesis in the hindbrain choroid plexus.

ZNF423 PECAM1

7.18e-042849233046507
Pubmed

Protein-protein interactions between large proteins: two-hybrid screening using a functionally classified library composed of long cDNAs.

THSD7A CNTNAP2 MADD

8.29e-0413049312421765
Pubmed

ESYT1 tethers the ER to mitochondria and is required for mitochondrial lipid and calcium homeostasis.

RAF1 PIGS SENP2 TRIM13

8.37e-0429949437931956
Pubmed

Neuron-specific protein network mapping of autism risk genes identifies shared biological mechanisms and disease-relevant pathologies.

PITPNM2 ETFB CNTNAP2 DAG1 ASAP1 MADD STAU1

1.03e-03113949736417873
Pubmed

The N6-methyladenosine-mediated lncRNA WEE2-AS1 promotes glioblastoma progression by stabilizing RPN2.

RAF1 MRPL20 ETFB STAU1

1.14e-0332549436168628
Pubmed

Association of genetic variants with chronic kidney disease in individuals with different lipid profiles.

PLA2G7 ENPP1 PECAM1

1.30e-0315249319578796
Pubmed

The STUbL RNF4 regulates protein group SUMOylation by targeting the SUMO conjugation machinery.

ZNF711 CCNT2 PIGS DAG1 HAT1 ZNF286A STX12

1.41e-03120349729180619
InteractionPRX interactions

RAF1 KCNMA1 DAG1

1.01e-0518483int:PRX
Cytoband3p21

ABHD5 DAG1

5.77e-04334923p21
GeneFamilyCyclins

CCNT2 CCNB3

1.19e-0328332473
GeneFamilyArmadillo repeat containing|Protein phosphatase 1 regulatory subunits

PPP1R21 ZFYVE16 STAU1

4.32e-03181333694
GeneFamilyZinc fingers C2H2-type|ZF class homeoboxes and pseudogenes

ZNF711 ZNF677 ZNF684 ZNF423 ZNF286A

9.19e-0371833528
ToppCellsystemic_lupus_erythematosus-flare-Lymphocytic_B-B_cell-male|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

ZNF711 CNTNAP2 GTSF1L DAG1 NCKAP1L

1.40e-0617549569ed3c7c45df6bef70f5f2ff003531160bf3b32b
ToppCellCOVID-19-kidney-AQP1+PLVAP+EC|COVID-19 / Disease (COVID-19 only), tissue and cell type

PITPNM2 THSD7A ZNF423 PECAM1 ASAP1

2.20e-0619249527ff3621e177e7932dd44dd6baa81551ea75a874
ToppCellsaliva-Severe-critical_progression_d12-22_with-steroid-Myeloid-Monocytic-Classical_Monocyte|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

ZFYVE16 ATP13A3 SNAPC1 ASAP1

8.99e-06119494e6f1b9f29dc8fe6b6132c7885234c385159da393
ToppCellfacs-Heart-Unknown-3m-Endothelial-endothelial_cell_of_coronary_artery|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ZNF711 NETO2 CCNB3 KCNMA1

1.76e-051414944aa4b3476dc5abefbd348353cfe711cd5fe3d52f
ToppCellfacs-Heart-Unknown-3m-Endothelial-coronary_vascular_endothelial_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ZNF711 NETO2 CCNB3 KCNMA1

1.76e-05141494e40c6f1b7fbaa46b3eaa55f1b37ef360b04370a8
ToppCellfacs-Heart-Unknown-3m-Endothelial|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ZNF711 NETO2 CCNB3 KCNMA1

1.80e-05142494759fbbd15b4fb313bd6269b7f087edafebd530ef
ToppCell3'-Adult-SmallIntestine-Endothelial-blood_vessel_EC-Mature_venous_EC|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

THSD7A PECAM1 ASAP1 CC2D2B

3.91e-05173494b57d14e2c2368304cb903562d06ce8228f53857c
ToppCellPND10-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-AEC-AEC_mature|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

THSD7A NETO2 PECAM1 ATP13A3

4.66e-051814944d7793026373cbcf04b15c77f95f1025d07d4c00
ToppCellPND10-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-AEC|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

THSD7A NETO2 PECAM1 ATP13A3

4.86e-051834943427f3cbe6ea81709750e7dd3ff378f03ae65eab
ToppCellCOVID-19-Heart-EC_3|COVID-19 / Disease (COVID-19 only), tissue and cell type

THSD7A ZNF423 PECAM1 CC2D2B

4.86e-05183494ff95382cfed592190d0636d2b750328471f82e0d
ToppCell3'-GW_trimst-2-LargeIntestine-Endothelial-blood_vessel_EC-Fetal_arterial_EC|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

THSD7A NETO2 PECAM1 GTSF1L

5.29e-0518749425efb82afe863a853ecdd781ad89026c993aaa67
ToppCellP03-Endothelial-large_vessel_endothelial_cell-endothelial_cell_of_artery|P03 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

THSD7A NETO2 PECAM1 ATP13A3

5.29e-0518749466ebe1788d51b3e17bec6cdb219f709756b4e530
ToppCell343B-Endothelial_cells-Endothelial-C_(Capillary_Aerocyte_)-|343B / Donor, Lineage, Cell class and subclass (all cells)

PPP1R21 NETO2 ENPP1 PECAM1

5.40e-05188494fe7143c36e4a883745862d3c3147cf751b440e46
ToppCell343B-Endothelial_cells-Endothelial-C_(Capillary_Aerocyte_)|343B / Donor, Lineage, Cell class and subclass (all cells)

PPP1R21 NETO2 ENPP1 PECAM1

5.40e-05188494cbf32b675a7cd0c808d5c9c22dfa7fa79fbe2437
ToppCellCOVID-19-lung-Vein_EC|lung / Disease (COVID-19 only), tissue and cell type

THSD7A ZNF423 PECAM1 CC2D2B

5.40e-05188494d582b76fc2faac526c9bf97503041129e1a6a211
ToppCellRA-10._Endothelium_II|World / Chamber and Cluster_Paper

THSD7A PECAM1 ATP13A3 ASAP1

5.51e-0518949475c248b9de5e2fb7a0baa8cdbab516e575cc4394
ToppCellCOVID-19-Heart-EC_3|Heart / Disease (COVID-19 only), tissue and cell type

THSD7A ZNF423 PECAM1 CC2D2B

5.63e-0519049478e7c502b0450c0b37652b1896a2a752fd8a2111
ToppCellCOVID-19-Endothelial_cells|COVID-19 / group, cell type (main and fine annotations)

PITPNM2 THSD7A ZNF423 PECAM1

5.63e-051904949fbd92cd6d4683b2490504d29c43cf42020433d4
ToppCellCOVID-19-lung-Macrophage_PPARGhi_CD5Lhi|lung / Disease (COVID-19 only), tissue and cell type

PLA2G7 ABHD5 KCNMA1 NCKAP1L

5.74e-05191494dab953682b8c9ed680a799161f837f792a7e4f33
ToppCellCOVID-19-lung-Macrophage_PPARGhi_CD5Lhi|COVID-19 / Disease (COVID-19 only), tissue and cell type

PLA2G7 ABHD5 KCNMA1 NCKAP1L

5.86e-05192494bcfb9c005166bc0b4f8ee2dfc0c1540e8bf0e1ff
ToppCellLPS-antiTNF-Endothelial-Endothelial-Activated_Gen_Cap|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PITPNM2 THSD7A ZNF423 PECAM1

5.86e-051924940aeb5351275c0a91151ea2d52b2cdde172da6731
ToppCellLPS-IL1RA+antiTNF-Endothelial-Endothelial-Gen_Cap|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PITPNM2 THSD7A ZNF423 PECAM1

5.98e-05193494e09387af84d2a0a526e54d4793e6e06c6739db53
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Afferent_/_Efferent_Arteriole_Endothelial_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ZNF423 PECAM1 ATP13A3 CC2D2B

5.98e-051934940b328f725f6feba263783eaca60c142e80df90f3
ToppCellLPS-antiTNF-Endothelial-Endothelial-Gen_Cap|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PITPNM2 THSD7A ZNF423 PECAM1

5.98e-051934946e1982d089a9de628e6006d23ff78a223fbd9f47
ToppCellLPS_only-Endothelial-Endothelial-Gen_Cap|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PITPNM2 THSD7A ZNF423 PECAM1

5.98e-05193494af5108260783e69a7d67896c5bf64f862525926d
ToppCellControl-Endothelial-Endothelial-Gen_Cap|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PITPNM2 THSD7A ZNF423 PECAM1

5.98e-05193494e1d546165dcc2392f540162206852c4717d7306f
ToppCellLPS-IL1RA-Endothelial-Endothelial-Gen_Cap|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PITPNM2 THSD7A ZNF423 PECAM1

6.10e-051944940b9cd96fa0b616da7cc90e92ff71157e9bba518f
ToppCellFetal_29-31_weeks-Immune-alveolar_macrophage_(MARCO_positive)-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

PLA2G7 ZFYVE16 ATP13A3 NCKAP1L

6.10e-051944943043f6230fa723037c8cf7123f611ae847b39fd4
ToppCellproximal-3-Endothelial-Capillary_Aerocyte|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

PITPNM2 NETO2 ENPP1 PECAM1

6.22e-0519549436b2e754ed7ff138ac05fb51f4494e5339669828
ToppCellChildren_(3_yrs)-Immune-alveolar_macrophage_(MARCO_positive)-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

PLA2G7 ZFYVE16 KCNMA1 ATP13A3

6.22e-051954949d649ac7d2af313481069c95349efc0c68449e2b
ToppCellproximal-Endothelial-Capillary_Aerocyte|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

PITPNM2 NETO2 ENPP1 PECAM1

6.22e-05195494f1cbf82484f489fe7e0b5de6a49ea28d69f04e1a
ToppCellAdult-Immune-alveolar_macrophage_(MARCO_positive)|Adult / Lineage, Cell type, age group and donor

ABHD5 KCNMA1 ASAP1 NCKAP1L

6.22e-0519549455e25f702af19146a161861cfd15f40bbda1dc35
ToppCell367C-Myeloid-Macrophage-FABP4+_Macrophage|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

TBC1D10C ABHD5 PECAM1 STX12

6.22e-05195494f664fe18856065baaa2837fc82ea946e45f6fcc3
ToppCellproximal-Endothelial-Capillary_Aerocyte-3|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

PITPNM2 NETO2 ENPP1 PECAM1

6.22e-0519549413168c9632b58dd65ecb365df3832d95e7325919
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ZNF423 PECAM1 ASAP1 CC2D2B

6.22e-0519549477e47d2e8b3eb7f7c9620369ccaf87581f923bdb
ToppCellIPF-Myeloid-Macrophage|IPF / Disease state, Lineage and Cell class

PLA2G7 KCNMA1 ATP13A3 ASAP1

6.47e-05197494a2ffb33c7cad6be43cbb8ed9a91338923cc07db4
ToppCell367C-Myeloid-Macrophage-FABP4+_Macrophage|Macrophage / Donor, Lineage, Cell class and subclass (all cells)

TBC1D10C ABHD5 PECAM1 STX12

6.47e-0519749407aee25e17dbb71e49f7da9fd9ed2537f4a72d82
ToppCellParenchymal-NucSeq-Endothelial-Endothelia_vascular-VE_pulmonary_venous|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

ZNF423 PECAM1 ASAP1 CC2D2B

6.47e-05197494b0036cf3f7e6edf8e43f16cd2f0f0e80471d2576
ToppCellParenchymal-NucSeq-Immune_Myeloid-Macrophage_alveolar|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

ABHD5 PECAM1 KCNMA1 NCKAP1L

6.60e-05198494e125eb8aa57c172e5518874da1bd25998292f5e2
ToppCellAdult-Immune-alveolar_macrophage_(MARCO_positive)-D231|Adult / Lineage, Cell type, age group and donor

PLA2G7 ABHD5 ASAP1 NCKAP1L

6.60e-0519849479a415e19cedde13a88f5043d71557363f102322
ToppCellParenchymal-NucSeq-Immune_Myeloid-Macrophage_alveolar-Macro_alveolar|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

ABHD5 PECAM1 KCNMA1 NCKAP1L

6.60e-051984940baeb8e2c199ff10bb5c829c523546af3c9227c1
ToppCellCOVID-19-lung-Capillary_2|lung / Disease (COVID-19 only), tissue and cell type

PITPNM2 THSD7A ZNF423 PECAM1

6.73e-05199494793ce71b78a68033ef4419ed571e1dd86b40124f
ToppCellIPF-Myeloid-Macrophage|Myeloid / Disease state, Lineage and Cell class

PLA2G7 ZFYVE16 KCNMA1 ATP13A3

6.73e-051994943c2b362d5e824e1a04830e70352f8818de984174
ToppCellTracheal-10x3prime_v2-Endothelial-Endothelia_vascular-VE_systemic_arterial|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

THSD7A ZNF684 PECAM1 CC2D2B

6.73e-05199494bd43a84e84d8acb8e1008b98a235cc5bd5f43586
ToppCellNeuronal-Inhibitory-iA-iA_1(SST_PAX6)-SST-BAGE2|Neuronal / cells hierarchy compared to all cells using T-Statistic

THSD7A ZNF423 CNTNAP2 SYT10

6.86e-0520049426f07d271e984f375145e4c10528fba44a5811e1
ToppCellBronchial-NucSeq-Immune_Myeloid|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

PLA2G7 PECAM1 KCNMA1 NCKAP1L

6.86e-052004942f5b71e55c2de0e77fdae6667eb57f333acc6cd1
ToppCellBronchial-NucSeq-Immune_Myeloid-Macrophage_alveolar|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

ABHD5 PECAM1 KCNMA1 NCKAP1L

6.86e-05200494a443e475e7a10c26a6173d1af961de6219e0e567
ToppCellNeuronal-Inhibitory-iA-iA_1(SST_PAX6)-SST-BAGE2-L1-2|Neuronal / cells hierarchy compared to all cells using T-Statistic

THSD7A ZNF423 CNTNAP2 SYT10

6.86e-05200494c3637827ceba16b0d7956c280dd2ddbc8b1ba55e
ToppCellBronchial-NucSeq-Immune_Myeloid-Macrophage_alveolar-Macro_alveolar|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

ABHD5 PECAM1 KCNMA1 NCKAP1L

6.86e-05200494ed785a6d08ca2b350dc3307b587eadfb2886d1f9
ToppCellsaliva-Severe-critical_progression_d12-22_with-steroid-Myeloid-Monocytic|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

ATP13A3 SNAPC1 ASAP1

4.31e-04134493197599d26db97c4fe815f4812f6362e606fe347a
ToppCell343B-Myeloid-Dendritic-cDC1|343B / Donor, Lineage, Cell class and subclass (all cells)

NETO2 ENPP1 ASAP1

5.75e-04148493e44cdc1c3f3314c549a0afa9298c8568022b9d8b
ToppCellsaliva-Severe-critical_progression_d28-40-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c01-LEF1|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)

ZNF711 CNTNAP2 KCNMA1

5.87e-041494934b44108c40376a6b73258df40d2424e68f991383
ToppCellE18.5-samps-Mesenchymal-Pericyte-pericyte_D|E18.5-samps / Age Group, Lineage, Cell class and subclass

TRAPPC11 ENPP1 WNK3

5.87e-04149493dcf68eb25733b5db2893728fe4dca5c7267eb58c
ToppCellTCGA-Brain-Primary_Tumor-Low_Grade_Glioma-Astrocytoma-3|TCGA-Brain / Sample_Type by Project: Shred V9

ATXN7L2 ZFYVE16 CCDC168

5.87e-04149493768877bade04ca0321593b8470b5011ad8270431
ToppCellfacs-Heart-RV-18m-Myeloid-monocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PLA2G7 ATF7IP2 NCKAP1L

6.33e-04153493af0ae08ff35f8210268457e5e15bcbe5d1f46d67
ToppCellfacs-Heart-RV-18m-Myeloid-monocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PLA2G7 ATF7IP2 NCKAP1L

6.33e-04153493984a2d847f4376183fdbab7ebc77c1bf7d448f44
ToppCellControl-Epithelial-Ionocyte|Epithelial / Disease state, Lineage and Cell class

ZNF677 CCNB3 KCNMA1

6.58e-041554934b9369b203a4d7071c56d3d8e6b450e9a0121c41
ToppCellChildren_(3_yrs)-Endothelial-endothelial_cell_of_artery-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

THSD7A ZNF423 PECAM1

6.83e-04157493275a4c6fef1fff8da2bdc48e3924ad05c5e5cfc8
ToppCell368C-Myeloid-Macrophage-SPP1+_Macrophage_4|368C / Donor, Lineage, Cell class and subclass (all cells)

PLA2G7 CCNB3 NCKAP1L

6.95e-04158493f9cfb110342be3c91aba9914805332f22ba89101
ToppCellCOVID-19-kidney-Epithelial_(EC)|kidney / Disease (COVID-19 only), tissue and cell type

ZNF423 PECAM1 CNTNAP2

7.21e-041604930d4880f85565d8c540c94a8f8109147b3029279a
ToppCell356C-Myeloid-Macrophage-SPP1+_Macrophage|356C / Donor, Lineage, Cell class and subclass (all cells)

PLA2G7 NETO2 KCNMA1

7.48e-041624932f19539c455d1e5d514725845234c7547020e6ad
ToppCellwk_08-11-Mesenchymal-Myofibro_&_SMC-Late_airway_SMC|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

PITPNM2 KCNMA1 ZNF286A

7.61e-041634931e8730d75cccf7292010683ab4e81a69d8e3bfa9
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-Degenerative_Endothelial_Cell-Degenerative_Peritubular_Capilary_Endothelial_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ZNF423 PECAM1 ASAP1

7.61e-0416349373c03e29a6d7a6863c5e9aa5e8b963ef691f1ddb
ToppCellkidney_cells-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Glomerular_Capillary_Endothelial_Cell_prolif|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

NETO2 PECAM1 ASAP1

7.75e-041644931592a5becad7e0f3f990f0d7581d75fcfc7da023
ToppCelltumor_Lymph_Node_/_Brain-T/NK_cells-CD8+/CD4+_Mixed_Th|tumor_Lymph_Node_/_Brain / Location, Cell class and cell subclass

CCNB3 GRK4 NCKAP1L

8.16e-04167493c0c944eae0514dc8e00d0c2892a0792e157695ec
ToppCellChildren_(3_yrs)-Endothelial-endothelial_cell_of_vein-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

ZNF423 PECAM1 CC2D2B

8.16e-04167493d7fe24cdc4b55a9555ce9e20699f5036b88148e9
ToppCell5'-Parenchyma_lung-Epithelial-Epithelial_transtional-secretory-club_cell-Club_(non-nasal)-Club_(non-nasal)_L.0.4.1.3|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

THSD7A NETO2 WNK3

8.16e-041674938fede587572d465cb63f7828141a574185bbb819
ToppCelldroplet-Pancreas-PANCREAS-30m-Hematologic-leukocyte|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PLA2G7 TBC1D10C NCKAP1L

8.31e-041684935946204d42307391bc2160abe12850815f350aea
ToppCellAdult-Endothelial-endothelial_cell_of_artery-D231|Adult / Lineage, Cell type, age group and donor

THSD7A ZNF423 CC2D2B

8.31e-04168493aca34c51758c65925ad24110294a72b2dea6db72
ToppCellkidney_cells-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell__prolif|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

NETO2 PECAM1 ASAP1

8.31e-0416849337249f38f8f04ec5743097259de67b106ca2b02f
ToppCell3'-Parenchyma_lung-Immune_Myeloid_mast-Myeloid_Mast/Baso-mast_cell-Mast_cells-Mast_cells_L.1.4.3.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ERF CNTNAP2 CCDC168

8.31e-0416849355f328353119cbdc521c782ebb8d163876f4186d
ToppCell10x_3'_v2v3-Neoplastic-Stem-like-OPC-like-OPC-like_Prolif-E|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

NETO2 DAG1 WNK3

8.45e-041694932833a8a7094e4d407eb923f2bc59b9b112c6bae4
ToppCellE16.5-Immune-Immune_Myeloid-Monocytic-Macrophage-AM-AM_prolif|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ATF7IP2 MADD NCKAP1L

8.45e-04169493305cedbd97059029d7d2a248a8a4b6cfe281aa54
ToppCell3'-Broncho-tracheal-Endothelial-Blood_vessel_EC-vein_endothelial_cell-EC_venous_pulmonary-EC_venous_pulmonary_L.2.2.1.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

THSD7A PECAM1 CC2D2B

8.59e-041704931a568efcff9c39b3f709b55a05d24710450a2657
ToppCellE16.5-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-AEC-AEC_prolif|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

THSD7A PECAM1 MADD

8.59e-0417049355fe16d98ea284d05fb899888e4569c685644c7b
ToppCell3'-Broncho-tracheal-Endothelial-Blood_vessel_EC-vein_endothelial_cell-EC_venous_pulmonary|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

THSD7A PECAM1 CC2D2B

8.59e-0417049366d41d794790e621d72ac37af995510537103c9c
ToppCell356C-Endothelial_cells-Endothelial-B_(Artery)-|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)

CCNT2 TRAPPC11 NCKAP1L

8.74e-041714936a2f88c2a62cb2f69797804e24eb1137a3e148de
ToppCell356C-Endothelial_cells-Endothelial-B_(Artery)|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)

CCNT2 TRAPPC11 NCKAP1L

8.74e-041714939be3554626408bb897d1f1c43b3ab4a92651f2e2
ToppCellControl-Endothelial_cells-Systemic_venous_endothelial_cells|Control / group, cell type (main and fine annotations)

THSD7A ZNF423 PECAM1

8.89e-04172493c55dce1ed3ed7312394b4e050e1de852a994e130
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_1-Inh_L1-5_VIP_KCNJ2|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

THSD7A NETO2 SYT10

9.19e-04174493fdadac1eaab2c4a67e4832f0901df22e893add6a
ToppCell3'-GW_trimst-1.5-SmallIntestine-Neuronal-Glial_immature-Glia_1_(DHH+)|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CTXND2 DAG1 SYT10

9.19e-04174493667035a11b68745fa8446d6c68214713be42710f
ToppCellAdult-Endothelial-endothelial_cell_of_vein-D231|Adult / Lineage, Cell type, age group and donor

ZNF423 PECAM1 CC2D2B

9.19e-041744932dd647c4fdf99fd1f7b838efef01baf2cbc3446d
ToppCellCOVID-19-kidney-CD-IC-A|COVID-19 / Disease (COVID-19 only), tissue and cell type

THSD7A SYT10 WNK3

9.50e-0417649345028197364c64e93e3ffe86aff773d47a477d49
ToppCellControl-Neuronal_cells|Control / group, cell type (main and fine annotations)

THSD7A ZNF423 ASAP1

9.50e-04176493c29d09ecf0eb17f767d78af4b7f2e7725c967ff8
ToppCellnormal_Pleural_Fluid-Myeloid_cells-CD141+_DCs|normal_Pleural_Fluid / Location, Cell class and cell subclass

ENPP1 ZNF423 ASAP1

9.50e-04176493195393b38f1335f2cb96125616d75c164a6026c2
ToppCellE16.5-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-AEC|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

THSD7A PECAM1 ATP13A3

9.50e-0417649377516048aefbe1f48e825052756df0c310c1c486
ToppCellControl-Neuronal_cells-Neuronal_cells|Control / group, cell type (main and fine annotations)

THSD7A ZNF423 ASAP1

9.50e-0417649398c07d26ba0dc0fe15ca0ea81f633d4591782bd1
ToppCellE16.5-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-AEC-AEC_mature|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

THSD7A PECAM1 ATP13A3

9.50e-0417649396779273b94345250cf53ba671203345b43d9e00
ToppCellIIH-mDC1-|IIH / Condition, Cell_class and T cell subcluster

ENPP1 ZNF423 ASAP1

9.50e-04176493bb80a3e595d071f6cc8b042984b8d9490e377eef
ToppCellIIH-mDC1|IIH / Condition, Cell_class and T cell subcluster

ENPP1 ZNF423 ASAP1

9.50e-04176493a75dc132a1061006fd1cb305bd314784fca07ea6
ToppCellPBMC-Mild-cDC_11|Mild / Compartment, Disease Groups and Clusters

ZNF711 NETO2 ENPP1

9.66e-04177493974305e4c0eff90134c4e58cf11b955d1eee0501
ToppCellfacs-Lung-3m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell-pulmonary_artery_endothelial_cell_l27|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

THSD7A ZNF423 PECAM1

9.81e-041784939f59a9af232d77bb55603a7776dbf9749ea652f2
ToppCell10x_5'_v1-Non-neoplastic-Myeloid-TAM-BDM-TAM-BDM_MHC|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

PLA2G7 ENPP1 WNK3

9.81e-04178493c90e9048fc786ba8559972ae25c25ecab4bc1b7c
ToppCellkidney_cells-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell__prolif|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PITPNM2 PECAM1 ASAP1

9.81e-04178493375156ba1c7b8592bf733c75f24968161f7cfa09
ToppCellPBMC-Severe-cDC_11|Severe / Compartment, Disease Groups and Clusters

ZNF711 NETO2 ENPP1

9.81e-041784930667abc05eb2254710b9c648c65b7cfdfe7831b7
ToppCell10x_5'_v1-Non-neoplastic-Myeloid-TAM-BDM-TAM-BDM_MHC-Z|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

PLA2G7 ENPP1 WNK3

9.81e-041784939e426ce23a4a33b91d139ad85685cf8483bcd01a
ToppCellfacs-Diaphragm-Limb_Muscle-3m-Lymphocytic-T_cell|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TBC1D10C NETO2 MADD

9.97e-041794938bf04a7ad1b0be6722ebfdceba3f083f07bf96c5
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_1-Inh_L1_SST_CXCL14|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

THSD7A NETO2 SYT10

9.97e-04179493c7afbd10072d36a35cd20ae73670d76b9cefd22d
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell_|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

ZNF423 PECAM1 ASAP1

9.97e-041794938f9e538c822940785130297712b75131812a4603
ToppCellfacs-Lung-24m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell-pulmonary_artery_endothelial_cell_l25|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

THSD7A PECAM1 ATP13A3

1.01e-03180493baa5825e6ce23a98d9c21d024a4b0ab8ba353d0c
Diseasemigraine disorder, HOMA-B

ETFB MADD

2.37e-055462EFO_0004469, MONDO_0005277
DiseaseAlzheimer disease, fasting blood glucose measurement

ETFB MADD

8.50e-059462EFO_0004465, MONDO_0004975
DiseaseSemantic-Pragmatic Disorder

ERF CNTNAP2

1.30e-0411462C0454655
DiseaseAuditory Processing Disorder, Central

ERF CNTNAP2

1.30e-0411462C0751257
DiseaseLanguage Delay

ERF CNTNAP2

1.30e-0411462C0023012
DiseaseLanguage Development Disorders

ERF CNTNAP2

1.30e-0411462C0023014
DiseaseSpeech Delay

ERF CNTNAP2

1.30e-0411462C0241210
DiseaseAutosomal recessive limb-girdle muscular dystrophy

TRAPPC11 DAG1

2.14e-0414462cv:C2931907
Diseasenervousness

ETFB MADD

2.81e-0416462NCIT_C74532
Diseasedisease free survival

CNTNAP2 CCDC168

3.58e-0418462EFO_0000409
Diseasefasting blood glucose measurement, HOMA-B, fasting blood insulin measurement

ETFB MADD

6.97e-0425462EFO_0004465, EFO_0004466, EFO_0004469
Diseaseresponse to angiotensin-converting enzyme inhibitor, response to angiotensin receptor blocker, angioedema

THSD7A KCNMA1

7.55e-0426462EFO_0005325, EFO_0005532, EFO_0010735
DiseaseLimb-girdle muscular dystrophy

TRAPPC11 DAG1

7.55e-0426462cv:C0686353
Diseaseatherosclerosis (is_marker_for)

PECAM1 STAU1

1.53e-0337462DOID:1936 (is_marker_for)

Protein segments in the cluster

PeptideGeneStartEntry
MKKQRTYKEKKPHKC

ZNF286A

231

Q9HBT8
KCKPQMNYDKLSRAL

ERF

71

P50548
PQKMSLDKYREKRKL

CCNT2

431

O60583
YCDMLLRKTPLSKKL

CUL5

411

Q93034
LGCRKKTPKAKYMYL

ATP13A3

1176

Q9H7F0
IQRKPEIYKKTCNKM

CC2D2B

201

Q6DHV5
KRKNLATYCRPVKAK

ATXN7L2

671

Q5T6C5
LYLMKAVCKKDKLQL

CCNB3

1191

Q8WWL7
SKLYKNCPKAMKRLV

RAF1

571

P04049
MVQKKKFCPRLLDYL

MADD

1

Q8WXG6
KKCGCKRPKMSIYKR

KCNMA1

691

Q12791
LASCRRKNPKKAKKM

GTSF1L

26

Q9H1H1
RKNPKKAKKMATCKY

GTSF1L

31

Q9H1H1
AMICYRKKRKGKLTL

DAG1

771

Q14118
KCYFLRKAKAKQMPV

PECAM1

621

P16284
MIFRCAKLVKNPYKA

CTXND2

31

A0A1B0GV90
LIRMYNIKKTCSDPK

NCKAP1L

26

P55160
SKLKKCGTYTKNMRP

ENPP1

236

P22413
KKQVFPIMCAYKLCK

PITPNM2

181

Q9BZ72
KKKAAAYMKSLRKPL

PPP1R21

521

Q6ZMI0
ANIIKMKKCYSPDKE

PLA2G7

326

Q13093
SPYKKKQRDLAKMRK

HAT1

361

O14929
MYSKPECLKLLLRSK

ASAP1

646

Q9ULH1
KPFKRLKSHLPYCKM

C17orf80

16

Q9BSJ5
ILKAKKTMPLSCRKQ

ATF7IP2

11

Q5U623
LPYRFRNKKMKTLKD

CNTNAP2

196

Q9UHC6
KCGIIKAKKPSISYM

CCDC168

1706

Q8NDH2
VRATGKMYACKKLQK

GRK4

206

P32298
EIPLKYKMKIKCRFQ

PIGS

91

Q96S52
LRKKCLKYLDSMGQK

SENP2

486

Q9HC62
MNMPKLKKFLCYLSQ

TRMT1L

646

Q7Z2T5
VKCTKARYLKKKNMR

MRPL20

51

Q9BYC9
FIVSMIYLACKKPKK

THSD7A

1621

Q9UPZ6
RYATLPNIMKAKKKK

ETFB

191

P38117
KMKEKYLNVSACPVK

GUCY1B2

141

O75343
KQPRKKVMACKTAFN

NETO2

371

Q8NC67
LKVLKKYPRLWCMTK

SIRT7

271

Q9NRC8
PKLLSYRMKKKIHRA

SNAPC1

141

Q16533
KMLKCVPCTYKKEPV

ABHD5

41

Q8WTS1
NPMRKKSYKSFEKCL

ZNF684

126

Q5T5D7
AQFKKYKCPRMKSHL

TRAPPC11

441

Q7Z392
KYNKIKISPKMPVCK

TRIM13

81

O60858
ELNALCMKLGKKPMY

STAU1

76

O95793
AYYQKKSRKKMCILV

STX12

241

Q86Y82
RYKKVKMQCRKGIPS

TBC1D10C

81

Q8IV04
VKMYLLPDRKKKFQT

SYT10

271

Q6XYQ8
PCVKNICNKYRKILK

ZNF677

231

Q86XU0
PVPRKKTYQCIKCQM

ZNF423

1161

Q2M1K9
LILRDKEPKMHKCKY

ZNF711

466

Q9Y462
MGKSCIKIPRKKYSD

ZFYVE16

1251

Q7Z3T8
KTYLKRFKVMKPKVL

WNK3

236

Q9BYP7