Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunction3',5'-cGMP-inhibited cyclic-nucleotide phosphodiesterase activity

PDE3A PDE3B

4.74e-0521382GO:0004119
GeneOntologyMolecularFunctionlow voltage-gated calcium channel activity

CACNA1H CACNA1G

1.42e-0431382GO:0008332
GeneOntologyMolecularFunctionminus-end-directed microtubule motor activity

DNAH7 DNAH12 DNAH11

2.44e-04181383GO:0008569
DomainDynein_heavy_chain_D4_dom

DNAH7 DNAH12 DNAH11

1.30e-04141363IPR024317
DomainDynein_heavy_dom-2

DNAH7 DNAH12 DNAH11

1.30e-04141363IPR013602
DomainDHC_N2

DNAH7 DNAH12 DNAH11

1.30e-04141363PF08393
DomainAAA_8

DNAH7 DNAH12 DNAH11

1.30e-04141363PF12780
DomainVDCC_T_a1

CACNA1H CACNA1G

1.57e-0431362IPR005445
DomainDHC_fam

DNAH7 DNAH12 DNAH11

1.61e-04151363IPR026983
DomainDynein_heavy

DNAH7 DNAH12 DNAH11

1.61e-04151363PF03028
DomainDynein_heavy_dom

DNAH7 DNAH12 DNAH11

1.61e-04151363IPR004273
DomainDC_STAMP-like

DCST2 OCSTAMP

3.13e-0441362IPR012858
DomainDC_STAMP

DCST2 OCSTAMP

3.13e-0441362PF07782
DomainCys-rich_flank_reg_C

CHADL TPBGL LRFN4 SLIT3 PKD1

5.09e-04901365IPR000483
DomainLRRCT

CHADL TPBGL LRFN4 SLIT3 PKD1

5.09e-04901365SM00082
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

VWA5B2 SEMA4B SZT2 CTC1 LONRF1 UBE3B SHC1 ZDHHC5 DGKQ NPHP4 CABLES1 HIRA ORC1 PRR12 C2CD3 ADAMTSL5 SETD5 CSPG4 PKD1 NINL CACNA1H HERC2 HAS3 ANKRD33B FOXK1

4.76e-1211051442535748872
Pubmed

Quantitative high-confidence human mitochondrial proteome and its dynamics in cellular context.

ACADS FAM210A SPATA18 GATB ADCK2 PYURF COX18 NUDT8 DNAJA3 CKMT2 GRPEL1 TIMM50 C1QBP MAIP1 TMEM223 BBC3 CKMT1A AFG1L

1.18e-0611361441834800366
Pubmed

Phosphodiesterase type 3A (PDE3A), but not type 3B (PDE3B), contributes to the adverse cardiac remodeling induced by pressure overload.

PDE3A PDE3B

1.70e-052144231051182
Pubmed

Cav3.2 subunit underlies the functional T-type Ca2+ channel in murine hearts during the embryonic period.

CACNA1H CACNA1G

1.70e-052144214988077
Pubmed

C2CD4A/B variants in the predisposition of lung cancer in the Chinese Han population.

C2CD4B C2CD4A

1.70e-052144235212842
Pubmed

Sexually dimorphic roles for the type 2 diabetes-associated C2cd4b gene in murine glucose homeostasis.

C2CD4B C2CD4A

1.70e-052144233492421
Pubmed

Pde3a and Pde3b regulation of murine pulmonary artery smooth muscle cell growth and metabolism.

PDE3A PDE3B

1.70e-052144239435735
Pubmed

Role of T-type calcium channel subunits in post-myocardial infarction remodelling probed with genetically engineered mice.

CACNA1H CACNA1G

1.70e-052144221622683
Pubmed

Ca(v)3.2 T-type Ca2+ channel-dependent activation of ERK in paraventricular thalamus modulates acid-induced chronic muscle pain.

CACNA1H CACNA1G

1.70e-052144220685979
Pubmed

A Common Type 2 Diabetes Risk Variant Potentiates Activity of an Evolutionarily Conserved Islet Stretch Enhancer and Increases C2CD4A and C2CD4B Expression.

C2CD4B C2CD4A

1.70e-052144229625024
Pubmed

A pathophysiological role of PDE3 in allergic airway inflammation.

PDE3A PDE3B

1.70e-052144229367458
Pubmed

T-type voltage-activated calcium channel Cav3.1, but not Cav3.2, is involved in the inhibition of proliferation and apoptosis in MCF-7 human breast cancer cells.

CACNA1H CACNA1G

1.70e-052144222469755
Pubmed

Chronic deficit in nitric oxide elicits oxidative stress and augments T-type calcium-channel contribution to vascular tone of rodent arteries and arterioles.

CACNA1H CACNA1G

1.70e-052144223436820
Pubmed

Phosphodiesterase 3A (PDE3A) deletion suppresses proliferation of cultured murine vascular smooth muscle cells (VSMCs) via inhibition of mitogen-activated protein kinase (MAPK) signaling and alterations in critical cell cycle regulatory proteins.

PDE3A PDE3B

1.70e-052144221632535
Pubmed

Different distribution of Cav3.2 and Cav3.1 transcripts encoding T-type Ca(2+) channels in the embryonic heart of mice.

CACNA1H CACNA1G

1.70e-052144221079360
Pubmed

Deficiency of T-type Ca2+ channels Cav3.1 and Cav3.2 has no effect on angiotensin II-induced hypertension but differential effect on plasma aldosterone in mice.

CACNA1H CACNA1G

1.70e-052144231042060
Pubmed

The Ca(v)3.1 T-type calcium channel is required for neointimal formation in response to vascular injury in mice.

CACNA1H CACNA1G

1.70e-052144222886848
Pubmed

Role of phosphodiesterase type 3A and 3B in regulating platelet and cardiac function using subtype-selective knockout mice.

PDE3A PDE3B

1.70e-052144217482796
Pubmed

Deletion of T-type calcium channels Cav3.1 or Cav3.2 attenuates endothelial dysfunction in aging mice.

CACNA1H CACNA1G

1.70e-052144229082441
Pubmed

The multifunctional protein GC1q-R interacts specifically with the i3 loop arginine cluster of the vasopressin V2 receptor.

AVPR2 C1QBP

1.70e-052144218358546
Pubmed

[Decreased mRNA expressions of T-type channel alpha1H and alpha1G in the sperm of varicocele patients and their implication].

CACNA1H CACNA1G

1.70e-052144222574369
Pubmed

Targeted disruption of PDE3B, but not PDE3A, protects murine heart from ischemia/reperfusion injury.

PDE3A PDE3B

1.70e-052144225877153
Pubmed

Blockade of T-type Ca(2+) channels inhibits human ovarian cancer cell proliferation.

CACNA1H CACNA1G

1.70e-052144221438841
Pubmed

β-Adrenergic stimulation increases Cav3.1 activity in cardiac myocytes through protein kinase A.

CACNA1H CACNA1G

1.70e-052144222808078
Pubmed

Defining a link with autosomal-dominant polycystic kidney disease in mice with congenitally low expression of Pkd1.

AVPR2 SHC1 PKD1

2.45e-0514144316400024
Pubmed

Identification of dynein heavy chain genes expressed in human and mouse testis: chromosomal localization of an axonemal dynein gene.

DNAH7 DNAH12 DNAH11

2.45e-051414439373155
Pubmed

A mitochondrial protein compendium elucidates complex I disease biology.

ACADS FAM210A GATB ADCK2 PYURF COX18 NUDT8 DNAJA3 CKMT2 GRPEL1 TIMM50 C1QBP TMEM223 CKMT1A AFG1L

3.14e-0510471441518614015
Pubmed

Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression.

ACADS FAM210A GATB ADCK2 COX18 NUDT8 DNAJA3 CKMT2 GRPEL1 C1QBP MAIP1 TMEM223 CKMT1A AFG1L

3.28e-059261441420877624
Pubmed

Creatine kinase and creatine transporter in normal, wounded, and diseased skin.

CKMT2 CKMT1A

5.09e-053144211874479
Pubmed

5,6-EET potently inhibits T-type calcium channels: implication in the regulation of the vascular tone.

CACNA1H CACNA1G

5.09e-053144224327205
Pubmed

A genome-wide association study in the Japanese population identifies susceptibility loci for type 2 diabetes at UBE2E2 and C2CD4A-C2CD4B.

C2CD4B C2CD4A

5.09e-053144220818381
Pubmed

Ethanol inhibition of a T-type Ca²+ channel through activity of protein kinase C.

CACNA1H CACNA1G

5.09e-053144223488970
Pubmed

Differential effect of T-type voltage-gated Ca2+ channel disruption on renal plasma flow and glomerular filtration rate in vivo.

CACNA1H CACNA1G

5.09e-053144224966091
Pubmed

A genome-wide association study confirms previously reported loci for type 2 diabetes in Han Chinese.

C2CD4B C2CD4A

5.09e-053144221799836
Pubmed

T-type channels: release a brake, engage a gear.

CACNA1H CACNA1G

5.09e-053144226488564
Pubmed

Molecular cloning and chromosomal assignment of the human homologue of the rat cGMP-inhibited phosphodiesterase 1 (PDE3A)--a gene involved in fat metabolism located at 11p 15.1.

PDE3A PDE3B

5.09e-05314428921398
Pubmed

Differential interactions of Na+ channel toxins with T-type Ca2+ channels.

CACNA1H CACNA1G

5.09e-053144218591418
Pubmed

Identification of the t-type calcium channel (Ca(v)3.1d) in developing mouse heart.

CACNA1H CACNA1G

5.09e-053144211230107
Pubmed

Prognostic relevance of a T-type calcium channels gene signature in solid tumours: A correlation ready for clinical validation.

CACNA1H CACNA1G

5.09e-053144228846697
Pubmed

Differential effects of peroxynitrite on human mitochondrial creatine kinase isoenzymes. Inactivation, octamer destabilization, and identification of involved residues.

CKMT2 CKMT1A

5.09e-053144212401781
Pubmed

Maintained coupling of oxidative phosphorylation to creatine kinase activity in sarcomeric mitochondrial creatine kinase-deficient mice.

CKMT2 CKMT1A

5.09e-05314429618231
Pubmed

Changes in the expression of the type 2 diabetes-associated gene VPS13C in the β-cell are associated with glucose intolerance in humans and mice.

C2CD4B C2CD4A

5.09e-053144227329800
Pubmed

Caveolin-3 regulates protein kinase A modulation of the Ca(V)3.2 (alpha1H) T-type Ca2+ channels.

CACNA1H CACNA1G

5.09e-053144221084288
Pubmed

Homeostatic plasticity and burst activity are mediated by hyperpolarization-activated cation currents and T-type calcium channels in neuronal cultures.

CACNA1H CACNA1G

5.09e-053144233547341
Pubmed

Calmodulin regulates Cav3 T-type channels at their gating brake.

CACNA1H CACNA1G

5.09e-053144228972185
Pubmed

Molecular characterization of the creatine kinases and some historical perspectives.

CKMT2 CKMT1A

5.09e-05314429746319
Pubmed

Expression of the mitochondrial creatine kinase genes.

CKMT2 CKMT1A

5.09e-05314427808456
Pubmed

Specific contribution of human T-type calcium channel isotypes (alpha(1G), alpha(1H) and alpha(1I)) to neuronal excitability.

CACNA1H CACNA1G

5.09e-053144211927664
Pubmed

ZnT-1 enhances the activity and surface expression of T-type calcium channels through activation of Ras-ERK signaling.

CACNA1H CACNA1G

5.09e-053144222572848
Pubmed

Two novel genes, Gpr113, which encodes a family 2 G-protein-coupled receptor, and Trcg1, are selectively expressed in taste receptor cells.

TAS1R3 ADGRF3

5.09e-053144215780750
Pubmed

PUMA facilitates EMI1-promoted cytoplasmic Rad51 ubiquitination and inhibits DNA repair in stem and progenitor cells.

FBXO5 BBC3

5.09e-053144233785736
Pubmed

T-type, but not L-type, voltage-gated calcium channels are dispensable for lymphatic pacemaking and spontaneous contractions.

CACNA1H CACNA1G

5.09e-053144231919478
Pubmed

Eps15 Homology Domain-containing Protein 3 Regulates Cardiac T-type Ca2+ Channel Targeting and Function in the Atria.

CACNA1H CACNA1G

5.09e-053144225825486
Pubmed

Use of gene targeting for compromising energy homeostasis in neuro-muscular tissues: the role of sarcomeric mitochondrial creatine kinase.

CKMT2 CKMT1A

5.09e-05314429125373
Pubmed

Alpha(1H) mRNA in single skeletal muscle fibres accounts for T-type calcium current transient expression during fetal development in mice.

CACNA1H CACNA1G

5.09e-053144211897840
Pubmed

Octamers of mitochondrial creatine kinase isoenzymes differ in stability and membrane binding.

CKMT2 CKMT1A

5.09e-053144210748055
Pubmed

Separate nuclear genes encode sarcomere-specific and ubiquitous human mitochondrial creatine kinase isoenzymes.

CKMT2 CKMT1A

5.09e-05314422324105
Pubmed

Electric field stimulation unmasks a subtle role for T-type calcium channels in regulating lymphatic contraction.

CACNA1H CACNA1G

5.09e-053144237739992
Pubmed

Downregulation of SWI5 and CTC1 genes: hepatitis B virus DNA polymerase transactivated protein 1-mediated inhibition of DNA repair.

CTC1 SWI5

5.09e-053144227265469
Pubmed

A novel gene family induced by acute inflammation in endothelial cells.

C2CD4B C2CD4A

5.09e-053144215527968
Pubmed

Impact of phosphodiesterases PDE3 and PDE4 on 5-hydroxytryptamine receptor4-mediated increase of cAMP in human atrial fibrillation.

PDE3A PDE3B

5.09e-053144232949251
Pubmed

Cardiac phenotype of mitochondrial creatine kinase knockout mice is modified on a pure C57BL/6 genetic background.

CKMT2 CKMT1A

5.09e-053144218948110
Pubmed

Murine 12(R)-lipoxygenase: functional expression, genomic structure and chromosomal localization.

C1QBP ALOX12B

5.09e-053144210100631
Pubmed

A quantitative approach to membrane binding of human ubiquitous mitochondrial creatine kinase using surface plasmon resonance.

CKMT2 CKMT1A

5.09e-053144211768757
Pubmed

Adult loss of Cacna1a in mice recapitulates childhood absence epilepsy by distinct thalamic bursting mechanisms.

CACNA1H CACNA1G

1.02e-044144231800012
Pubmed

Regulated degradation of the HIV-1 Vpu protein through a betaTrCP-independent pathway limits the release of viral particles.

FBXO5 BTRC

1.02e-044144217676996
Pubmed

Pharmacogenetics of antiepileptic drug efficacy in childhood absence epilepsy.

CACNA1H CACNA1G

1.02e-044144228165634
Pubmed

Functional importance of L- and P/Q-type voltage-gated calcium channels in human renal vasculature.

CACNA1H CACNA1G

1.02e-044144221788606
Pubmed

T-type Ca2+ channels elicit pro-proliferative and anti-apoptotic responses through impaired PP2A/Akt1 signaling in PASMCs from patients with pulmonary arterial hypertension.

CACNA1H CACNA1G

1.02e-044144228655554
Pubmed

Differential expression of adenine nucleotide converting enzymes in mitochondrial intermembrane space: a potential role of adenylate kinase isozyme 2 in neutrophil differentiation.

CKMT2 CKMT1A

1.69e-045144224587121
Pubmed

Activated protein C reverses epigenetically sustained p66Shc expression in plaque-associated macrophages in diabetes.

SHC1 F2R

1.69e-045144230271984
Pubmed

Isolation and characterization of the gene and cDNA encoding human mitochondrial creatine kinase.

CKMT2 CKMT1A

1.69e-04514422914937
Pubmed

Developmental expression patterns of alpha1H T-type Ca2+ channels during spermatogenesis and organogenesis in mice.

CACNA1H CACNA1G

1.69e-045144212060068
Pubmed

Five human genes encoding F-box proteins: chromosome mapping and analysis in human tumors.

FBXO5 BTRC

1.69e-045144210828603
Pubmed

T-type calcium channels functionally interact with spectrin (α/β) and ankyrin B.

CACNA1H CACNA1G

1.69e-045144229720258
Pubmed

Hundreds of variants clustered in genomic loci and biological pathways affect human height.

FNDC3B C2CD4A CABLES1 SCMH1 SLIT3 LTBP2

1.83e-04198144620881960
Pubmed

The interactome of intact mitochondria by cross-linking mass spectrometry provides evidence for coexisting respiratory supercomplexes.

ACADS FAM210A GATB DNAJA3 CKMT2 GRPEL1 C1QBP CKMT1A

2.02e-04382144829222160
Pubmed

The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment.

FNDC3B SEMA4B CHRDL2 CILP PGLYRP2 THSD1 KIRREL2 SLIT3 PRRT3 IGSF9 ADGRF3 HS3ST2 IL17RB

2.41e-049851441312975309
Pubmed

Cyclin A2-cyclin-dependent kinase 2 cooperates with the PLK1-SCFbeta-TrCP1-EMI1-anaphase-promoting complex/cyclosome axis to promote genome reduplication in the absence of mitosis.

FBXO5 BTRC

2.53e-046144219822658
Pubmed

Novel roles of Pkd2 in male reproductive system development.

PKD1 SMAD1

2.53e-046144224951251
Pubmed

Enhanced expression of L-type Cav1.3 calcium channels in murine embryonic hearts from Cav1.2-deficient mice.

CACNA1H CACNA1G

3.53e-047144212900400
Pubmed

Creatine and creatinine metabolism.

CKMT2 CKMT1A

3.53e-047144210893433
Pubmed

Isolation of several human axonemal dynein heavy chain genes: genomic structure of the catalytic site, phylogenetic analysis and chromosomal assignment.

DNAH12 DNAH11

3.53e-04714429256245
Pubmed

Genome-wide association analysis in East Asians identifies breast cancer susceptibility loci at 1q32.1, 5q14.3 and 15q26.1.

CABLES1 ZBED6

3.53e-047144225038754
Pubmed

Pkd1 is required for male reproductive tract development.

PKD1 SMAD1

3.53e-047144223933588
Pubmed

Identification of motif-based interactions between SARS-CoV-2 protein domains and human peptide ligands pinpoint antiviral targets.

VWA5B2 RGL3 KIRREL2 DNAH7 CCDC17 DNAH11

4.38e-04233144637704626
Pubmed

Plk1 regulates activation of the anaphase promoting complex by phosphorylating and triggering SCFbetaTrCP-dependent destruction of the APC Inhibitor Emi1.

FBXO5 BTRC

4.69e-048144215469984
Pubmed

Development of the vertebral morphogenetic field in the mouse: interactions between Crossveinless-2 and Twisted Gastrulation.

CHRDL2 SMAD1

4.69e-048144218789316
Pubmed

Evolutionary insights into T-type Ca2+ channel structure, function, and ion selectivity from the Trichoplax adhaerens homologue.

CACNA1H CACNA1G

4.69e-048144228330839
Pubmed

Neuroepithelial progenitors generate and propagate non-neuronal action potentials across the spinal cord.

CACNA1H CACNA1G

4.69e-048144234478646
Pubmed

Intracellular calcium plays an essential role in cardiac development.

CACNA1H CACNA1G

4.69e-048144212761855
Pubmed

International Union of Pharmacology. XLVIII. Nomenclature and structure-function relationships of voltage-gated calcium channels.

CACNA1H CACNA1G

6.01e-049144216382099
Pubmed

The F-Box Domain-Dependent Activity of EMI1 Regulates PARPi Sensitivity in Triple-Negative Breast Cancers.

FBXO5 BTRC

6.01e-049144230554948
Pubmed

Multiple renal cysts, urinary concentration defects, and pulmonary emphysematous changes in mice lacking TAZ.

AVPR2 PKD1

6.01e-049144218172001
Pubmed

Inhibition of microtubule assembly in osteoblasts stimulates bone morphogenetic protein 2 expression and bone formation through transcription factor Gli2.

BTRC SMAD1

6.01e-049144219103752
Pubmed

Two members of the TRPP family of ion channels, Pkd1l3 and Pkd2l1, are co-expressed in a subset of taste receptor cells.

TAS1R3 PKD1

7.50e-0410144216805797
Pubmed

Cav3.2 T-type calcium channel is required for the NFAT-dependent Sox9 expression in tracheal cartilage.

CACNA1H CACNA1G

7.50e-0410144224778262
Pubmed

Evidence for an early role for BMP4 signaling in thymus and parathyroid morphogenesis.

GCM2 SMAD1

7.50e-0410144220043899
Pubmed

Signal peptide prediction based on analysis of experimentally verified cleavage sites.

SEMA4B CHRDL2 PGLYRP2 KIRREL2 PRRT3 IL17RB

8.41e-04264144615340161
Pubmed

Regulation of embryonic kidney branching morphogenesis and glomerular development by KISS1 receptor (Gpr54) through NFAT2- and Sp1-mediated Bmp7 expression.

PKD1 SMAD1

9.14e-0411144220375015
InteractionTOP3B interactions

VWA5B2 SEMA4B SZT2 CTC1 LONRF1 UBE3B SHC1 ZDHHC5 DGKQ NPHP4 CABLES1 HIRA ORC1 PRR12 C2CD3 ADAMTSL5 SETD5 CSPG4 PKD1 C1QBP NINL CACNA1H HERC2 HAS3 ANKRD33B FOXK1

7.57e-06147013926int:TOP3B
GeneFamilyDyneins, axonemal

DNAH7 DNAH12 DNAH11

6.73e-0517863536
GeneFamilyGlycosyltransferase family 2

B3GNTL1 HAS3

3.31e-046862428
GeneFamilyPleckstrin homology domain containing|Rho guanine nucleotide exchange factors|C2 domain containing

C2CD4B C2CD4A C2CD3

6.62e-0436863823
ToppCellfacs-Lung-18m-Hematologic-lymphocytic-immature_innate_lymphoid_cell-Ly6g5b+_T|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SEMA4B CXCR3 TPBGL EYA2 SNAI3 FCHO1 CD72 IL17RB

9.28e-0817314380a355386210a13927ea29b10b64cb059459952d4
ToppCellfacs-Lung-18m-Hematologic-lymphocytic-immature_innate_lymphoid_cell|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SEMA4B CXCR3 TPBGL EYA2 SNAI3 FCHO1 CD72 IL17RB

9.28e-0817314383678b300cad4effd7f49bfb043305ed512693848
ToppCell5'-Airway_Nasal-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell-Multiciliated_(nasal)-Multiciliated_(nasal)_L.0.3.1.1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CERKL SPATA18 DNAH7 CFAP100 DNAH12 CCDC17 CCDC157 DNAH11

1.26e-0718014381f1af4474f3f0ac3c0d6b1a6c875c354d36d8eec
ToppCellFetal_29-31_weeks-Epithelial-ciliated_cell-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

CERKL SPATA18 DNAH7 CFAP100 DNAH12 CCDC17 CCDC157 DNAH11

1.31e-071811438dfce05bd472f67e6e2bb60ebd6fd34f0a9aeeca6
ToppCellASK428-Immune-B_cell|ASK428 / Donor, Lineage and Cell class of Lung cells from Dropseq

CXCR3 ADCK2 PYURF NUDT8 ZBED6 RIMS1 BBC3

1.54e-061741437b5a7a612a515736cf3489afd0f6ad2054d54526f
ToppCellCiliated_cells-B-Donor_02|World / lung cells shred on cell class, cell subclass, sample id

CERKL SPATA18 DNAH7 CFAP100 DNAH12 CCDC17 DNAH11

1.73e-061771437c38138fb5ad9766c2d240811210c854338cd612e
ToppCellFetal_29-31_weeks-Epithelial-ciliated_cell-D062|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

CERKL SPATA18 DNAH7 CFAP100 DNAH12 CCDC17 DNAH11

1.79e-061781437de5d50d7ca9ee9eb62f50c88a0c6d47f0694b2e6
ToppCellCiliated_cells-A-Myositis-ILD_01|World / lung cells shred on cell class, cell subclass, sample id

SPATA18 DNAH7 CFAP100 DNAH12 RIMS1 CCDC17 DNAH11

2.23e-06184143707c5a9633ccdcd18771e3230d6198a55c400afa6
ToppCellChildren_(3_yrs)-Epithelial-ciliated_cell-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

CERKL SPATA18 DNAH7 CFAP100 DNAH12 CCDC17 DNAH11

2.23e-0618414375daff849625f2f41d56615569c0ed59cd733b34c
ToppCellNS-moderate-d_16-33-Epithelial-Ciliated|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

CERKL SPATA18 DNAH7 CFAP100 DNAH12 CCDC17 DNAH11

2.31e-0618514375e689c2fb36ce3ac2adc8d15f67107f21cf68868
ToppCellAdult-Epithelial-ciliated_cell-D175|Adult / Lineage, Cell type, age group and donor

CERKL SPATA18 DNAH7 CFAP100 DNAH12 CCDC17 DNAH11

2.31e-06185143730f4980dee6cd5959655f8d74049f3bfb5312611
ToppCellFetal_29-31_weeks-Epithelial-ciliated_cell-D150|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

CERKL SPATA18 DNAH7 CFAP100 DNAH12 CCDC17 DNAH11

2.31e-0618514373e39a3cb534dfe2301930f3e2f7e8cefb522c158
ToppCellCOVID-19-Epithelial_cells-Airway_ciliated|COVID-19 / group, cell type (main and fine annotations)

CERKL SPATA18 DNAH7 CFAP100 DNAH12 CCDC17 DNAH11

2.31e-06185143718a40f0a338aa398d81384b5159fb80ce8a2020c
ToppCellNS-critical-d_16-33-Epithelial-Ciliated|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

CERKL SPATA18 DNAH7 CFAP100 DNAH12 CCDC17 DNAH11

2.40e-06186143776033438426d8f9c72cd6691a7baf92104c9f03d
ToppCellFetal_29-31_weeks-Epithelial-ciliated_cell|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

CERKL SPATA18 DNAH7 CFAP100 DNAH12 CCDC17 DNAH11

2.49e-0618714379e10ed56090d82589bc457788282f664b70ace4b
ToppCellEpithelial-ciliated_cell|World / Lineage, Cell type, age group and donor

CERKL SPATA18 DNAH7 CFAP100 DNAH12 CCDC17 DNAH11

2.57e-06188143761a459f3fe57e5728efc72637ff2edc2d343492b
ToppCellAdult-Epithelial-ciliated_cell-D231|Adult / Lineage, Cell type, age group and donor

CERKL SPATA18 DNAH7 CFAP100 DNAH12 CCDC17 DNAH11

2.57e-06188143734b11f72ca73153d02edcd09b38983ad1a504659
ToppCellChildren_(3_yrs)-Epithelial-ciliated_cell|Children_(3_yrs) / Lineage, Cell type, age group and donor

CERKL SPATA18 DNAH7 CFAP100 DNAH12 CCDC17 DNAH11

2.57e-0618814372b6dfc88be9ded7b88da9fe78a9cd9f9b3af8af3
ToppCellCOVID-19-lung-Ciliated|COVID-19 / Disease (COVID-19 only), tissue and cell type

CERKL SPATA18 DNAH7 CFAP100 DNAH12 CCDC17 DNAH11

2.67e-061891437a2da5debd10f27b1280b40141ef0bfef007cc72c
ToppCellChildren_(3_yrs)-Epithelial-ciliated_cell-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

CERKL SPATA18 DNAH7 CFAP100 DNAH12 CCDC17 DNAH11

2.67e-06189143768a3cf7763d6f9b95d6d6524eff7a16042703f1d
ToppCellAdult-Epithelial-ciliated_cell|Adult / Lineage, Cell type, age group and donor

CERKL SPATA18 DNAH7 CFAP100 DNAH12 CCDC17 DNAH11

2.67e-061891437b679920f0993e917dd86da082113bfbd85ea1ca5
ToppCellCOVID-19-lung-Ciliated|lung / Disease (COVID-19 only), tissue and cell type

CERKL SPATA18 DNAH7 CFAP100 DNAH12 CCDC17 DNAH11

2.67e-06189143727329c4661aebabd19fac7fe5dca263fe99d76f3
ToppCellNS-moderate-d_0-4|moderate / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

CERKL SPATA18 DNAH7 CFAP100 MAPRE3 CCDC17 DNAH11

3.06e-061931437ea345d34440b25f65358a53dc72831998d1c3620
ToppCellNS-critical-d_07-13-Epithelial-Ciliated|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

CERKL SPATA18 DNAH7 CFAP100 DNAH12 CCDC17 DNAH11

3.17e-0619414371ae8a10e508e672e6677f0e3c986ac30d05adeb3
ToppCellmoderate-Epithelial-Ciliated|Epithelial / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

SPATA18 DNAH7 CFAP100 MAPRE3 DNAH12 CCDC17 DNAH11

3.28e-0619514373486eae5fdb062a75a907b896c9d7b396d2aa195
ToppCellmoderate-Epithelial-Ciliated|moderate / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

SPATA18 DNAH7 CFAP100 MAPRE3 DNAH12 CCDC17 DNAH11

3.28e-061951437e80f5cdf0b18066b3e6c2f5452e58f101c67932c
ToppCellNS-moderate-d_0-4-Epithelial-Ciliated|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

CERKL SPATA18 DNAH7 CFAP100 DNAH12 CCDC17 DNAH11

3.51e-06197143771fea4aa6ce96c7693fa94792d08770622873850
ToppCellcellseq-Mesenchymal-Myocytic|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

ARHGEF17 F2R CSPG4 SLIT3 HES4 CACNA1H LTBP2

3.75e-06199143720e62a7029fa0d214244cdf2a481fc5d78290438
ToppCellParenchymal-10x5prime-Stromal-Myofibroblastic|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

PDE3A ARHGEF17 CSPG4 SLIT3 HES4 CACNA1H LTBP2

3.75e-06199143720f760d92c351a1dac4cc0a424c443ea03a179fe
ToppCellParenchymal-10x5prime-Stromal-Myofibroblastic-Muscle_smooth_pulmonary|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

PDE3A ARHGEF17 CSPG4 SLIT3 HES4 CACNA1H LTBP2

3.75e-0619914377c272a1aa7f3e931ad5d20809719d85b3bce4cb0
ToppCellParenchyma_COVID-19-Stromal-TX-Smooth_muscle-2|Parenchyma_COVID-19 / Sample group, Lineage and Cell type

PDE3A ARHGEF17 CKMT2 CSPG4 SLIT3 HES4 CACNA1H

3.75e-061991437c8bc05dece8b8a87d4a7a3e8112b924e15217de1
ToppCellLung_Parenchyma-Severe-Mesenchymal-Mesenchymal-Smooth_muscle-2-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

PDE3A ARHGEF17 CKMT2 CSPG4 SLIT3 HES4 CACNA1H

3.75e-06199143778b245d40c1e169ff2d26907b63d732e34529c5f
ToppCellLung_Parenchyma-Severe-Mesenchymal-Mesenchymal-Smooth_muscle-2|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)

PDE3A ARHGEF17 CKMT2 CSPG4 SLIT3 HES4 CACNA1H

3.75e-0619914378e1e95c3a4b856415af208be6ad977e575bac189
ToppCellBronchial-10x5prime-Epithelial-Epi_airway_ciliated|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

CERKL SPATA18 DNAH7 CFAP100 DNAH12 CCDC17 DNAH11

3.87e-06200143752aef65f01b06cd98056f17977efe525aee6eb6f
ToppCellBronchial-10x5prime-Epithelial-Epi_airway_ciliated-Ciliated|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

CERKL SPATA18 DNAH7 CFAP100 DNAH12 CCDC17 DNAH11

3.87e-06200143755c148238d5c80c1faa3428a917ae8075be2c145
ToppCellBiopsy_Other_PF-Epithelial-Differentiating_Ciliated|Biopsy_Other_PF / Sample group, Lineage and Cell type

CERKL SPATA18 DNAH7 CFAP100 DNAH12 CCDC17 DNAH11

3.87e-062001437f7b4581d958afbd68f9045af619aaca0ab463439
ToppCellParenchymal-10x5prime-Epithelial-Epi_airway_ciliated|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

CERKL SPATA18 DNAH7 CFAP100 DNAH12 CCDC17 DNAH11

3.87e-06200143785c98da55f7cd4ffdf9d309b56c8cc5d43f3c04c
ToppCelldistal-3-Hematologic-Platelet/Megakaryocyte|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

SPATA18 C2CD4A DNAH7 DNAH12 IGSF9 CCDC17 DNAH11

3.87e-062001437f5f5a8b0e4d802d95dc42646dd5e7d7daaad72b4
ToppCellParenchymal-10x5prime-Epithelial-Epi_airway_ciliated-Ciliated|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

CERKL SPATA18 DNAH7 CFAP100 DNAH12 CCDC17 DNAH11

3.87e-06200143712bc7d95c4166d12487081a76d210b7abe5991b0
ToppCell367C-Myeloid-Macrophage-FABP4+_Macrophage_2|Macrophage / Donor, Lineage, Cell class and subclass (all cells)

SPATA18 DNAH7 FCHO1 ORC1 RAD51AP2 IL17RB

9.82e-0615214367a1072315cce71eefe2d32149a107d5648999968
ToppCellsevere_COVID-19-NK_CD56bright|severe_COVID-19 / disease group, cell group and cell class (v2)

CXCR3 DUSP2 FREM3 AFDN-DT NINL HAS3

1.22e-051581436c2e8d96fc29aa2388b92b4fd81d2726e1f7a053f
ToppCellkidney_cells-Adult_normal_reference-Mesenchymal--glomerular_mesenchymal_cell-Renin-positive_Juxtaglomerular_Granular_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PDE3A DUSP2 ARHGEF17 CSPG4 SLIT3 HES4

1.41e-051621436c7114e24cb5525abb9780ca3d35dbcc4eabd4b64
ToppCellkidney_cells-Adult_normal_reference-Mesenchymal--glomerular_mesenchymal_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PDE3A DUSP2 ARHGEF17 CSPG4 SLIT3 HES4

1.41e-051621436f1851a173d3bcca2981d934161ec85d1cc0af5a2
ToppCellkidney_cells-Adult_normal_reference-Mesenchymal-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PDE3A DUSP2 ARHGEF17 CSPG4 SLIT3 HES4

1.41e-0516214365d902bb31e691aea9749617cc88303c2448f24b8
ToppCellFetal_29-31_weeks-Mesenchymal-vascular_smooth_muscle_cell-D062|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

PDE3A ADAMTSL5 SLIT3 HES4 CACNA1H LTBP2

1.46e-05163143651dee6c21cbeca4e17d1cc386e203f0c403089e8
ToppCellCiliated_cells-B-Donor_03|World / lung cells shred on cell class, cell subclass, sample id

SPATA18 DNAH7 CFAP100 DNAH12 CCDC17 DNAH11

1.51e-051641436fd30c55d0d75ef8b9396435d836187168095152b
ToppCellCiliated_cells-B-Donor_08|World / lung cells shred on cell class, cell subclass, sample id

CERKL SPATA18 CHADL DNAH7 DNAH12 DNAH11

1.62e-0516614364b1056aad8a99827835242b8ab0c7f2bb84471f1
ToppCellsaliva-Severe-critical_progression_d28-40-Lymphocytic-Lymphocytic_B-B_cell-B_c01-TCL1A|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)

CERKL CFAP100 RAD51AP2 DNAH12 CCDC17 DNAH11

1.73e-0516814369a8709d34865cfa668d8f3335dc34fc86fc32482
ToppCelldroplet-Liver-nan-3m-Myeloid-Kupffer_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

C2CD4B CTC1 RASSF10 CHADL P3H2 NINL

1.98e-051721436f814b6134ad608015765399d54cc1e5e1873ed34
ToppCell3'-Distal_airway-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.3.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SPATA18 DNAH7 CFAP100 DNAH12 CCDC17 DNAH11

2.05e-051731436c3762655caa79ac4879876f470d32578a3c93b01
ToppCellfacs-Lung-EPCAM-18m-Lymphocytic-T_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SEMA4B CXCR3 TPBGL EYA2 SNAI3 CD72

2.11e-051741436aae7ab9df5a78716034ddfd5bd47adc69912d624
ToppCellfacs-Lung-EPCAM-18m-Lymphocytic-Ly6g5b+_T|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SEMA4B CXCR3 TPBGL EYA2 SNAI3 CD72

2.11e-051741436d9489c4196d103ead8cb6279492bbe563a222e45
ToppCellfacs-Lung-Endomucin-3m-Lymphocytic|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SEMA4B AVPR2 DUSP2 LMNTD2 FCHO1 CD72

2.26e-0517614369b58734017ceabe81f490dd0b9f3192bc903d455
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PDE3A ARHGEF17 CSPG4 SLIT3 CACNA1H DNAH11

2.33e-051771436a8625d14682183cf77cb51eaf11bc15a3528f586
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PDE3A ARHGEF17 CSPG4 SLIT3 CACNA1H DNAH11

2.33e-0517714363645e2f4a48283f290f85c49c3e79e3f58ac9aa6
ToppCellChildren_(3_yrs)-Mesenchymal-pericyte_cell-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

PDE3A ARHGEF17 CSPG4 HES4 CACNA1H LTBP2

2.40e-051781436185b44700f06ec58b3c09c80520502166c965fd6
ToppCell3'-Broncho-tracheal-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell-Multiciliated_(nasal)-Multiciliated_(nasal)_L.0.3.1.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SPATA18 DNAH7 CFAP100 DNAH12 CCDC17 DNAH11

2.40e-0517814363b12db04006db6e94fc45649a4b3a63b92f21a61
ToppCell15-Airway-Epithelial-Multiciliated_precursor|Airway / Age, Tissue, Lineage and Cell class

SPATA18 DNAH7 CFAP100 DNAH12 CCDC157 DNAH11

2.40e-051781436d8e0a696bdd6af6422d72af0413f9dbd6bc02afa
ToppCellfacs-Lung-Endomucin-3m-Lymphocytic-B_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SEMA4B AVPR2 DUSP2 LMNTD2 FCHO1 CD72

2.48e-051791436de3245e1ee269e422de0308d0dd3623e4e9eb182
ToppCellfacs-Lung-Endomucin-3m-Lymphocytic-B_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SEMA4B AVPR2 DUSP2 LMNTD2 FCHO1 CD72

2.48e-051791436c41c11171dfb40e5ddea6bf97d9373eb03a2321b
ToppCell3'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.3.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SPATA18 DNAH7 CFAP100 DNAH12 CCDC17 DNAH11

2.56e-05180143692fb01b91261b3103454924cde56add337b41844
ToppCell5'-GW_trimst-1.5-SmallIntestine-Epithelial-neuro-epithelial-I_cells_(INS+)|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

VWA5B2 CERKL GCM2 RGL3 DNAH12 ASCL2

2.56e-0518014360c5d9245b8a7cc34ad52522d31559906cda55bdf
ToppCellControl-Epithelial_cells-Airway_ciliated|Control / group, cell type (main and fine annotations)

SPATA18 DNAH7 CFAP100 DNAH12 CCDC17 DNAH11

2.72e-051821436fb725d10d9ed25dfc6d5bb69cfef78513f7d3e8f
ToppCellwk_08-11-Mesenchymal-Chondrocyte-Resting_chondrocyte|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

CHRDL2 MATN1 CHADL EYA2 NRK CSPG4

2.72e-05182143600a148b1e499bf16325491536d187d4dd6b70c06
ToppCell5'-Adult-LymphNode-Endothelial-lymphatic_endothelial-LEC1_(ACKR4+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CHRDL2 SHC1 RASSF10 THSD1 HS3ST2 SMAD1

2.81e-0518314362d0d3b486498a7903fa9a1f48b189291da49c430
ToppCellCiliated_cells-B-Myositis-ILD_01|World / lung cells shred on cell class, cell subclass, sample id

SPATA18 DNAH7 CFAP100 DNAH12 CCDC17 DNAH11

2.98e-051851436f012c243343e1d1956db19b34d062e9b13de2b2a
ToppCell15-Airway-Epithelial-Multiciliated_cell|Airway / Age, Tissue, Lineage and Cell class

SPATA18 DNAH7 CFAP100 DNAH12 CCDC17 DNAH11

2.98e-0518514360998b6bf44287eebbf39249fff23fc3689e44c4e
ToppCellCiliated_cells-B-IPF_01|World / lung cells shred on cell class, cell subclass, sample id

SPATA18 DNAH7 CFAP100 DNAH12 CCDC17 DNAH11

3.08e-051861436f72267d533fd0c5280d9741ceee3dd116300a7e4
ToppCell5'-GW_trimst-2-LargeIntestine-Mesenchymal-Pericytes-Immature_pericyte|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

RGL3 ARHGEF17 CSPG4 HES4 CACNA1H DNAH11

3.08e-0518614366568358812f0ca4e0161a1a1b29682fbced35c79
ToppCellTCGA-Kidney-Primary_Tumor-Renal_Cell_Carcinoma-Kidney_Clear_Cell_Renal_Carcinoma-2|TCGA-Kidney / Sample_Type by Project: Shred V9

PDE3A THSD1 F2R CSPG4 SLIT3 LTBP2

3.08e-0518614361e6526fc9e9381b7ace864588cc7bd80194338d6
ToppCellNS-moderate-d_07-13-Epithelial-Ciliated|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

SPATA18 DNAH7 CFAP100 DNAH12 CCDC17 DNAH11

3.08e-05186143685787ff207f109ec7e3c0f729ba9bda739c2fdc9
ToppCellCiliated_cells-B-SSc-ILD_01|World / lung cells shred on cell class, cell subclass, sample id

SPATA18 DNAH7 CFAP100 DNAH12 CCDC17 DNAH11

3.17e-0518714362b4262c2e7c7830a976be168cee6eeb738d4feda
ToppCellAdult-Mesenchymal-pericyte_cell|Adult / Lineage, Cell type, age group and donor

PDE3A ARHGEF17 CSPG4 SLIT3 HES4 CACNA1H

3.17e-05187143662759efb660179402fb574ce5701c89a2e17bcfe
ToppCellmulticiliated|World / shred by cell class for bronchial biopsy

SPATA18 DNAH7 CFAP100 DNAH12 CCDC17 DNAH11

3.27e-0518814366833c1f0f265ef5448fa65033550ed7efc2f8d7b
ToppCell21-Trachea-Epithelial-Multiciliated_cell|Trachea / Age, Tissue, Lineage and Cell class

SPATA18 DNAH7 CFAP100 DNAH12 CCDC17 DNAH11

3.27e-051881436803bf76a85b3033d2a04b08dd2c03ce9c15529ba
ToppCell367C-Epithelial_cells-Epithelial-F_(Ciliated)-|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

SPATA18 DNAH7 CFAP100 DNAH12 CCDC17 DNAH11

3.27e-05188143682c006f43c93f4a867953a446864f02b44536a23
ToppCell367C-Epithelial_cells-Epithelial-F_(Ciliated)|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

SPATA18 DNAH7 CFAP100 DNAH12 CCDC17 DNAH11

3.27e-051881436da59b5c0a4b11690a39a964c1a0a83e66aa0972b
ToppCellCiliated_cells-B-Donor_07|World / lung cells shred on cell class, cell subclass, sample id

SPATA18 DNAH7 CFAP100 DNAH12 CCDC17 DNAH11

3.27e-051881436606907c865bd2f11bb6474932716550f7723d858
ToppCell(7)_Epithelial_cells-(7)_Epithelial-F_(Ciliated)|(7)_Epithelial_cells / Lung cell shreds - cell class (v4) and cell subclass (v4)

SPATA18 DNAH7 CFAP100 DNAH12 CCDC17 DNAH11

3.27e-0518814365ba5cbb403518026e9040379fb5d99339ea977d8
ToppCell(7)_Epithelial-F_(Ciliated)|World / Lung cell shreds - cell class (v4) and cell subclass (v4)

SPATA18 DNAH7 CFAP100 DNAH12 CCDC17 DNAH11

3.27e-0518814369a8b9f745eed9f129b6c582f48fbbaaacbebb4b3
ToppCellTransplant_Alveoli_and_parenchyma-Epithelial-Ciliated_1|Transplant_Alveoli_and_parenchyma / Tissue, Lineage and Cell class of Lung Cells from 10X

SPATA18 DNAH7 CFAP100 DNAH12 CCDC17 DNAH11

3.36e-051891436dc440015949a768188c67661b6be63b1ead1a0f0
ToppCelltumor_Lung-Fibroblasts-Pericytes|Fibroblasts / Location, Cell class and cell subclass

ARHGEF17 P3H2 CSPG4 HES4 CACNA1H DNAH11

3.36e-0518914369c407b17d7945e81e1ae6c18452f5d20fb09d563
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PDE3A ARHGEF17 CSPG4 SLIT3 CACNA1H MYO18B

3.36e-051891436127ad2ba3e794df8cce2eee3e4171bccb5aad51b
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PDE3A ARHGEF17 CSPG4 SLIT3 CACNA1H MYO18B

3.36e-0518914362cfb4d12f75678d1619f4743838a0e954bd57761
ToppCellCOPD-Epithelial-Ciliated|Epithelial / Disease state, Lineage and Cell class

SPATA18 DNAH7 CFAP100 DNAH12 CCDC17 DNAH11

3.36e-0518914363e77883db34722b9ce0a03ea74caefc92dc7feff
ToppCellCiliated|World / shred by cell class for parenchyma

SPATA18 DNAH7 CFAP100 DNAH12 CCDC17 DNAH11

3.36e-051891436711181ca3b9102fb155168b646b0a9b09ff215b2
ToppCell343B-Epithelial_cells-Epithelial-F_(Ciliated)|343B / Donor, Lineage, Cell class and subclass (all cells)

SPATA18 DNAH7 CFAP100 DNAH12 CCDC17 DNAH11

3.46e-051901436169e600e95878000acf5d11f813f9028c7249646
ToppCell343B-Epithelial_cells-Epithelial-F_(Ciliated)-|343B / Donor, Lineage, Cell class and subclass (all cells)

SPATA18 DNAH7 CFAP100 DNAH12 CCDC17 DNAH11

3.46e-0519014360cc36117c793d83cf4a1f66f47758a07d6712bd3
ToppCellEpithelial_cells-Ciliated_cells-A|Epithelial_cells / lung cells shred on cell class, cell subclass, sample id

SPATA18 DNAH7 CFAP100 DNAH12 CCDC17 DNAH11

3.46e-051901436549d813a8f23b175875e53347928941f143e236c
ToppCellCiliated_cells-B|World / lung cells shred on cell class, cell subclass, sample id

SPATA18 DNAH7 CFAP100 DNAH12 CCDC17 DNAH11

3.46e-0519014367031fbedc13be1a00f6333ad6d51849c3739c2e6
ToppCellTransplant_Alveoli_and_parenchyma-Epithelial-Ciliated_1|Epithelial / Tissue, Lineage and Cell class of Lung Cells from 10X

SPATA18 DNAH7 CFAP100 DNAH12 CCDC17 DNAH11

3.46e-051901436a90a38fccdbf75a286b4d258fc54920c02b282f7
ToppCellCiliated_cells-A|World / lung cells shred on cell class, cell subclass, sample id

SPATA18 DNAH7 CFAP100 DNAH12 CCDC17 DNAH11

3.46e-051901436cd87731aaa7d252424f79cfce9f7931457f17bdf
ToppCellEpithelial_cells-Ciliated_cells-B|Epithelial_cells / lung cells shred on cell class, cell subclass, sample id

SPATA18 DNAH7 CFAP100 DNAH12 CCDC17 DNAH11

3.46e-051901436426a4806f6e39d4d57c6746609d30bb3ca62df7d
ToppCellLPS-IL1RA-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_3|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PDE3A CILP ARHGEF17 CSPG4 SLIT3 CACNA1H

3.46e-05190143673d94fbae92029745989a8712eed8b99fd84c193
ToppCell356C-Epithelial_cells-Epithelial-F_(Ciliated)-|356C / Donor, Lineage, Cell class and subclass (all cells)

SPATA18 DNAH7 CFAP100 DNAH12 CCDC17 DNAH11

3.57e-0519114368a5a2188b13ef4bbfd626a42565566708a751c1b
ToppCell5'-Airway_Nasal-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CERKL SPATA18 DNAH7 DNAH12 CCDC17 CCDC157

3.57e-051911436683e5c7e6173644f01e67c98ab7b75d7cb9cce99
ToppCell356C-Epithelial_cells-Epithelial-F_(Ciliated)-|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

SPATA18 DNAH7 CFAP100 DNAH12 CCDC17 DNAH11

3.57e-051911436dad675251e129254955eac179c84a641a4864586
ToppCell356C-Epithelial_cells-Epithelial-F_(Ciliated)|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

SPATA18 DNAH7 CFAP100 DNAH12 CCDC17 DNAH11

3.57e-0519114366d2cf41ee946137c039ddcc13593fc3f670afbba
ToppCellfacs-Lung-3m-Mesenchymal-myofibroblast|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ARHGEF17 F2R P3H2 CSPG4 CACNA1G LTBP2

3.57e-051911436fd8331c7abdd999f55ba43d307945c6abfccbf84
ToppCell356C-Epithelial_cells-Epithelial-F_(Ciliated)|356C / Donor, Lineage, Cell class and subclass (all cells)

SPATA18 DNAH7 CFAP100 DNAH12 CCDC17 DNAH11

3.57e-051911436e314dd8f1a841cab847ae3703bedfe1bc623ac61
DrugLY 294002; Up 200; 10uM; HL60; HT_HG-U133A

ACADS CILP ADCK2 F2R NINL CD72 CACNA1G LTBP2 BTRC

3.92e-0619414396195_UP
DrugDihydrostreptomycin sulfate [5490-27-7]; Up 200; 2.8uM; MCF7; HT_HG-U133A

MATN1 THSD1 F2R NPHP4 CKMT2 MAPRE3 BTRC FAM110B

3.84e-0519914386228_UP
DrugInocor (TN)

PDE3A PDE3B

3.92e-0521432CID000656683
DrugRS-1893

PDE3A PDE3B

3.92e-0521432CID000128386
DrugM-HN

PDE3A PDE3B CKMT2 CKMT1A

4.11e-05311434CID000015450
Drugthemisone

DUSP2 CACNA1H CACNA1G

5.12e-05121433CID000016235
Drugmyo-inositol

PDE3B GALNS AVPR2 DUSP2 SHC1 NTSR2 DGKQ F2R CKMT2 NRK PKD1 CD72 CACNA1H CACNA1G ALOX12B CKMT1A

5.23e-0581114316CID000000892
DrugD-myo-inositol-1,4,5-triphosphate

TRPC7 GCM2 AVPR2 DUSP2 SHC1 DGKQ F2R TULP1 NRK PKD1 CD72 CACNA1H CACNA1G

6.28e-0556814313CID000000806
DrugIntegrilin

DUSP2 F2R CKMT2 CKMT1A

8.39e-05371434CID000123610
DrugSureCN4406168

PDE3A PDE3B

1.17e-0431432CID011502028
DrugSureCN4395097

PDE3A PDE3B

1.17e-0431432CID011610011
DrugSureCN4401117

PDE3A PDE3B

1.17e-0431432CID011718172
DrugSureCN4402206

PDE3A PDE3B

1.17e-0431432CID011516917
DrugWIN 62582

PDE3A PDE3B

1.17e-0431432CID005487388
DrugSureCN4397066

PDE3A PDE3B

1.17e-0431432CID011538627
DrugSureCN4401121

PDE3A PDE3B

1.17e-0431432CID011611819
DrugSureCN4404748

PDE3A PDE3B

1.17e-0431432CID011502895
Drug1,3-dioxoisoindoline-5-carboxamide

CACNA1H CACNA1G

1.17e-0431432CID010679219
DrugSureCN4411688

PDE3A PDE3B

1.17e-0431432CID011523192
DrugSureCN4405038

PDE3A PDE3B

1.17e-0431432CID011546172
DrugSureCN4405912

PDE3A PDE3B

1.17e-0431432CID011682920
Drugpelrinone

PDE3A PDE3B

1.17e-0431432CID000055919
DrugSureCN4398032

PDE3A PDE3B

1.17e-0431432CID011532088
DrugSureCN4406373

PDE3A PDE3B

1.17e-0431432CID011711104
DrugSureCN4394894

PDE3A PDE3B

1.17e-0431432CID011711103
DrugSureCN5995113

PDE3A PDE3B

1.17e-0431432CID011640499
DrugCHEMBL219123

PDE3A PDE3B

1.17e-0431432CID016102624
Druggermitrine

PDE3A PDE3B

1.17e-0431432CID000011217
DrugSureCN4411840

PDE3A PDE3B

1.17e-0431432CID011567407
DrugSureCN4401113

PDE3A PDE3B

1.17e-0431432CID011544858
DrugSureCN4405883

PDE3A PDE3B

1.17e-0431432CID011516351
DrugSureCN4407211

PDE3A PDE3B

1.17e-0431432CID011553351
DrugSureCN4401096

PDE3A PDE3B

1.17e-0431432CID011710801
Diseaselysophosphatidylcholine 18:2 measurement

EYA2 CCDC85A AFDN-DT RIMS1

6.78e-06281304EFO_0010361
Diseasetotal cholesterol measurement, response to escitalopram, response to citalopram

SLIT3 RIMS1

5.30e-0481302EFO_0004574, EFO_0006329, EFO_0007871
Diseaseosteoarthritis, hip

CHADL P3H2 LTBP2 HERC2

7.45e-04921304EFO_1000786
Diseaseactinic keratosis

DEF8 HERC2

1.69e-03141302EFO_0002496
Diseasetelomere length

CTC1 MATN1 CABLES1 P3H2 NINL CACNA1H

2.70e-033131306EFO_0004505
Diseasesquamous cell carcinoma

DEF8 HERC2 DNAH11

3.26e-03671303EFO_0000707
Diseasepolymyositis

UBE3B DGKQ

3.47e-03201302EFO_0003063
Diseaseleft atrial function

CILP MYO18B

3.83e-03211302EFO_0004294

Protein segments in the cluster

PeptideGeneStartEntry
LCGSPLRRAQIVSTP

nan

106

Q8N976
SPRRVSRCSPTGLIK

CASTOR3

26

Q8NAP1
RRGPPARVTLTCLAV

CXCR3

161

P49682
PRTVSRLARRTCLEP

FAM210A

6

Q96ND0
PRPLLTGLRLTTECN

ADGRF3

156

Q8IZF5
LRQGLSLLRPSECPR

ADCK2

21

Q7Z695
TDSVQRLGRASCLPP

ADCK2

226

Q7Z695
RDTGRTTALPPALCL

CCDC17

426

Q96LX7
LRSPGFRQLCRIPST

COX18

296

Q8N8Q8
TRRPVLAPCLRGAVL

CTC1

416

Q2NKJ3
LPYLRGTSRPLRGCL

CSPG4

156

Q6UVK1
PRLCTRPFGLLSVRA

C1QBP

36

Q07021
LARASGPARRALCPR

ACADS

6

P16219
LRLRGFPSSICLLRP

ALLC

361

Q8N6M5
ALGSVLRPLRARPGC

BBC3

66

Q96PG8
SCPRIAPGLLRVSSR

AFDN-DT

216

Q9Y6Z5
ALDPRAPAGTLCLRT

BTRC

536

Q9Y297
LRPLAQSPLRGRCVG

AFG1L

11

Q8WV93
FGRLRSLVLPPACVR

DGKQ

236

P52824
GNSPRLVITPLTDRC

DNAH11

1861

Q96DT5
DASLPGTLPVLNRRC

GATB

101

O75879
AVTSPAVGRILPCRT

CD72

76

P21854
LPSSRTGRTLLGQPC

CCDC157

656

Q569K6
ASLPAPRRLSGLCAR

DANCR

61

P0C864
RLGAPLPFRAIRVTC

ARRDC1

31

Q8N5I2
RPEEGRRSLRPCSVL

CAPN14

386

A8MX76
CVLSVLTPRSVRGPE

ANKRD33B

286

A6NCL7
AARRRPASPELLRCS

ASCL2

21

Q99929
GISRVRPLKTCSRPI

RAD51AP2

1116

Q09MP3
RPLKTCSRPIRIGLS

RAD51AP2

1121

Q09MP3
RVVLSRERPCPARGA

RASSF10

146

A6NK89
RGRPCSDDVTPLRLS

PGBD4

506

Q96DM1
RARPASAAVLVPLCS

NUDT8

26

Q8WV74
PGLRRRASCRPTTAA

ARHGEF17

36

Q96PE2
RPRSAPRTSSCAERL

FCHO1

411

O14526
RPAALPRSLSRLREC

FAM189A1

11

O60320
PRSLSRLRECPGRSR

FAM189A1

16

O60320
RSRLLGAPRCLRGPS

HS3ST2

46

Q9Y278
GPPQERSRLCSIALS

SLC17A3

116

O00476
LAPQSRGHLCRTRPT

MATN1

26

P21941
SLPCGAVRLRTPAVA

MAIP1

16

Q8WWC4
AVCQPLRARSLLTPR

NTSR2

136

O95665
TLKRGPLSCHTRPRA

ERVS71-1

321

P61550
LALSLRPSPRLLCTA

GRPEL1

16

Q9HAV7
RSPCDRPRVIESLRG

HERC2

4076

O95714
RLCRDRLPPATASAT

LONRF1

156

Q17RB8
SRCRSRSLSPICPRS

SPATA18

501

Q8TC71
LSLAALCRSAVPREP

IL17RB

6

Q9NRM6
GPRAVRCRLSLVLRP

C2CD4B

281

A6NLJ0
RCRLSLVLRPPGTAR

C2CD4B

286

A6NLJ0
RRRARGPPAAVLACL

DUSP2

56

Q05923
RRSLPPGLLRRVSST

PDE3A

426

Q14432
VPVIRPRRRSSCVSL

PDE3B

286

Q13370
DTLPSCAVRAGLLRP

PGLYRP2

501

Q96PD5
GNSPRLVITPLTDRC

DNAH12

1221

Q6ZR08
TLGLRRPVHSSCIPS

PHRF1

396

Q9P1Y6
SSREPVPLLSIRGCA

LMNTD2

436

Q8IXW0
SGGSRLSPSRIRLCV

NALF2

421

O75949
PVAARAPESTLRRLC

HAUS5

21

O94927
VCRPLRYAGLVSPRL

OR2I1P

126

Q8NGU4
ECVRELATRPGRLSP

P3H2

286

Q8IVL5
ISSTRCPKAPGRVLV

CHRDL2

326

Q6WN34
AASCPSSPRIRRRIS

RGL3

506

Q3MIN7
LPPTARRSRLGVLFC

NEURL2

181

Q9BR09
SVRSRRCLRLPGEEP

ADAMTSL5

66

Q6ZMM2
VRGCSTLPPSRSRVI

NPHP4

836

O75161
CGPLLSARTRARRPE

F2R

16

P25116
VLPTCLSRRGHAAPR

RIMS1

1186

Q86UR5
SRPVSAQRRVCPRGT

FGF11

21

Q92914
AGPLRFTRICRDPVT

PABPC5

41

Q96DU9
FTRICRDPVTRSPLG

PABPC5

46

Q96DU9
TPRCAAPQIRSRSLA

ORC1

466

Q13415
NPLCSPSRAALLTGR

GALNS

76

P34059
EATRGALSQRPCRPR

C2CD3

2311

Q4AC94
NAPLRRCRTLSGSPR

CABLES1

301

Q8TDN4
SPGICLRRRAPSSDS

CACNA1G

2326

O43497
ERLSCIGSPIVSPRI

FBXO5

91

Q9UKT4
SLPVRTLSIAPGQCR

FNDC3B

661

Q53EP0
GNSPRLVITPLTDRC

DNAH7

1296

Q8WXX0
GSACRLPAAPRLTER

REXO1L1P

181

Q8IX06
RALLALRSAPCSPVL

FOXK1

11

P85037
LCSVAPRGLAPNTRL

CERKL

436

Q49MI3
GRTLVCRSRPPAHRI

CFAP100

576

Q494V2
IGRCLPTLPGSFRLS

CCDC85A

476

Q96PX6
RSLGPGTCTLPLAQR

LTBP2

676

Q14767
SGFPRCLRTVPELIR

ALOX12B

551

O75342
CLRQLGPSRRPASLS

HES4

146

Q9HCC6
TSGRLSNVAPPCILR

MAPRE3

171

Q9UPY8
CRAPISLRGVPSEAR

DEF8

281

Q6ZN54
PACGVSRRPSLQRSK

FAM110B

246

Q8TC76
TRLLCLRSLLDPSPR

FAM98C

126

Q17RN3
PANLTCRSRGDARPT

KIRREL2

141

Q6UWL6
RPSSSVSLLCRPICR

KRTAP10-5

216

P60370
RYVSSGCRPLRPLLN

KRTAP26-1

116

Q6PEX3
ALKLPSPRRGSVALC

HAS3

76

O00219
ISILSRRCLLRPSEP

DCST2

481

Q5T1A1
STCGRRLLSPILLPS

HIRA

761

P54198
SRPSARRTPIKGRQC

CHADL

736

Q6NUI6
FPCRQRPLGATTRVR

GRIFIN

106

A4D1Z8
RGTARSPSLSRLLCR

CACNA1H

2001

O95180
SLTSCGPRALLTLRP

DNAJA3

51

Q96EY1
RCRSLSDVRVRGPVP

PRRT3

871

Q5FWE3
GPRAVSCRLSLVLRP

C2CD4A

286

Q8NCU7
SCRLSLVLRPPGTAL

C2CD4A

291

Q8NCU7
LVLRPPGTALRQCST

C2CD4A

296

Q8NCU7
TGRSIRGLSLPPACT

CKMT1A

166

P12532
RGLSLPPACTRAERR

CKMT1A

171

P12532
RTASCQRPGRPARVA

PKD1

2191

P98161
VTTTPLNCGPRLRVL

IYD

236

Q6PHW0
RTGRSIRGLSLPPAC

CKMT2

166

P17540
IRGLSLPPACTRAER

CKMT2

171

P17540
CDSTPRLATAPLGRR

ODF3L2

6

Q3SX64
VSQLFSRSCPRVLPR

EYA2

46

O00167
LRLPTSSRCRPLRVL

NRK

371

Q7Z2Y5
SSRCRPLRVLHGEPS

NRK

376

Q7Z2Y5
GATATRRCRLTPLPH

FREM3

201

P0C091
PGRSTCLRQTLPLSF

SZT2

1731

Q5T011
RCRLASALRGTRAPP

PYURF

6

Q96I23
CTLPDGSRLQLRPAI

GCM2

91

O75603
CPRPRVRLGSEIRDS

SEMA4B

821

Q9NPR2
RRRRPLLPDGTFSSC

SETD5

766

Q9C0A6
ELRLTSARCPLLPAR

OCSTAMP

381

Q9BR26
VSRSGPLCLPESRAL

PNKP

346

Q96T60
LNPRRLPDLVSSCRS

PRR12

1116

Q9ULL5
PLRPAASCRGQAERL

NINL

961

Q9Y2I6
PPSTASAVRRLCSRG

SCMH1

536

Q96GD3
TLRCPLYRGTLVPRL

SMCR8

816

Q8TEV9
PSNCVTIPRSLDGRL

SMAD1

61

Q15797
RSSAVACISLPLLPR

SNAI3

61

Q3KNW1
SIIGCRVRRDPPNST

B3GNTL1

136

Q67FW5
RFLCPPGSLRRDTER

CILP

136

O75339
IEGRNTRKPCSPTRL

RNF17

491

Q9BXT8
PIETSGARCSSPRRL

SLIT3

456

O75094
LRPAPQGRTVRCRLT

TULP1

296

O00294
LTRSCRGAFRSPRPL

SWI5

131

Q1ZZU3
ALGFCSPRPDLVSRL

ZNF707

46

Q96C28
LRPLLTCRPLQGTTL

TMEM223

16

A0PJW6
RLGSRGLCTRLATPP

TIMM50

16

Q3ZCQ8
LRSRTRPSSPVCTRF

TAS1R3

51

Q7RTX0
LQPSRPTRARGTCSV

ZC3H3

171

Q8IXZ2
CVARPGTPSLLRFAL

ZSWIM9

261

Q86XI8
CSPYARILRSRRSPL

KIF20A

866

O95235
RERRRVCLTSFPSSP

THSD1

361

Q9NS62
LAGPVRRSRLVRPIC

TMPRSS9

921

Q7Z410
LEPVTLRCVARGSPL

IGSF9

151

Q9P2J2
VSLSLPSLPSRRGRC

TBC1D29P

131

Q9UFV1
LSPTLRPRRRCLESS

MYO18B

2376

Q8IUG5
SRVLCSSPAPRYLGR

ZDHHC5

241

Q9C0B5
ILLTRGLARPRPCLS

UBE3B

211

Q7Z3V4
GLARPRPCLSKGTLT

UBE3B

216

Q7Z3V4
GPCLSVRARLTYRNP

VWA5B2

26

Q8N398
LSVPVSSLSPGRRCN

ZBED6

6

P86452
GCSAPPSRLASALRR

ZNHIT2

56

Q9UHR6
KSLLRSRRTGCPPAL

ZNF217

746

O75362
VPDSRRLRCAAPRAL

TPBGL

256

P0DKB5
CSGSPAERRQLLPRA

TYMP

361

P19971
PCSRPLSSILGRSNL

SHC1

211

P29353
LRSLLCCARGRTPPS

AVPR2

336

P30518
IAPCSKLGRTLRSPF

TRPC7

371

Q9HCX4
QRATLRCRALGDPAP

LRFN4

296

Q6PJG9