Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	monoatomic ion transmembrane transporter activity	GABRG1 CACNA1E CFTR KCNK12 SLC26A1 SLC3A2 SLC9A2 PIEZO2 CLCN5 SCN1A KCNQ3 KCNS1 CTNS SLC45A1 TRPV5 UQCRFS1P1	5.85e-05	793	130	16	GO:0015075
GeneOntologyMolecularFunction	RNA-directed DNA polymerase activity	ERVK-7 TERT ERVK-8	9.31e-05	14	130	3	GO:0003964
GeneOntologyMolecularFunction	DNA polymerase activity	POLE ERVK-7 TERT ERVK-8	1.07e-04	38	130	4	GO:0034061
GeneOntologyMolecularFunction	inorganic molecular entity transmembrane transporter activity	GABRG1 CACNA1E CFTR KCNK12 SLC26A1 SLC3A2 SLC9A2 CLCN5 SCN1A KCNQ3 KCNS1 CTNS SLC45A1 TRPV5 UQCRFS1P1	1.25e-04	758	130	15	GO:0015318
GeneOntologyMolecularFunction	anandamide 8,9 epoxidase activity	CYP2D7 CYP2D6	2.50e-04	4	130	2	GO:0062187
GeneOntologyMolecularFunction	anandamide 11,12 epoxidase activity	CYP2D7 CYP2D6	2.50e-04	4	130	2	GO:0062188
GeneOntologyMolecularFunction	steroid 21-monooxygenase activity	CYP2D7 CYP2D6	2.50e-04	4	130	2	GO:0004509
GeneOntologyMolecularFunction	progesterone 21-hydroxylase activity	CYP2D7 CYP2D6	2.50e-04	4	130	2	GO:0106309
GeneOntologyMolecularFunction	gated channel activity	GABRG1 CACNA1E CFTR KCNK12 PIEZO2 CLCN5 SCN1A KCNQ3 KCNS1	3.44e-04	334	130	9	GO:0022836
GeneOntologyMolecularFunction	anandamide 14,15 epoxidase activity	CYP2D7 CYP2D6	6.20e-04	6	130	2	GO:0062189
GeneOntologyMolecularFunction	anandamide epoxidase activity	CYP2D7 CYP2D6	6.20e-04	6	130	2	GO:0062186
GeneOntologyMolecularFunction	transmembrane transporter activity	GABRG1 CACNA1E CFTR MFSD4A KCNK12 SLC7A6 SLC26A1 SLC3A2 SLC9A2 PIEZO2 CLCN5 SCN1A KCNQ3 KCNS1 CTNS SLC45A1 TRPV5 UQCRFS1P1	6.41e-04	1180	130	18	GO:0022857
GeneOntologyMolecularFunction	monoatomic ion channel activity	GABRG1 CACNA1E CFTR KCNK12 PIEZO2 CLCN5 SCN1A KCNQ3 KCNS1 TRPV5	8.54e-04	459	130	10	GO:0005216
GeneOntologyMolecularFunction	3-chloroallyl aldehyde dehydrogenase activity	ALDH3A1 ALDH3A2	8.65e-04	7	130	2	GO:0004028
GeneOntologyMolecularFunction	voltage-gated monoatomic ion channel activity	CACNA1E KCNK12 CLCN5 SCN1A KCNQ3 KCNS1	1.24e-03	182	130	6	GO:0005244
GeneOntologyMolecularFunction	voltage-gated channel activity	CACNA1E KCNK12 CLCN5 SCN1A KCNQ3 KCNS1	1.31e-03	184	130	6	GO:0022832
GeneOntologyMolecularFunction	monoatomic cation transmembrane transporter activity	CACNA1E KCNK12 SLC3A2 SLC9A2 PIEZO2 SCN1A KCNQ3 KCNS1 CTNS SLC45A1 TRPV5 UQCRFS1P1	1.34e-03	664	130	12	GO:0008324
GeneOntologyMolecularFunction	protein-glutamine gamma-glutamyltransferase activity	TGM7 EPB42	1.47e-03	9	130	2	GO:0003810
GeneOntologyMolecularFunction	transporter activity	GABRG1 CACNA1E CFTR MFSD4A KCNK12 SLC7A6 SLC26A1 SLC3A2 SLC9A2 PIEZO2 CLCN5 SCN1A KCNQ3 KCNS1 CTNS SLC45A1 TRPV5 UQCRFS1P1	1.75e-03	1289	130	18	GO:0005215
GeneOntologyBiologicalProcess	homophilic cell adhesion via plasma membrane adhesion molecules	PCDHGA10 PCDHGA9 PCDHGA5 PCDHGA4 PCDHGA2 PCDHGA1 PCDHGA12 NECTIN4 PCDHGA8	2.75e-06	187	129	9	GO:0007156
GeneOntologyBiologicalProcess	cell-cell adhesion via plasma-membrane adhesion molecules	PCDHGA10 PCDHGA9 PCDHGA5 PCDHGA4 PCDHGA2 PCDHGA1 TENM2 PCDHGA12 NECTIN4 PCDHGA8	2.81e-05	313	129	10	GO:0098742
Domain	Cadherin_tail	PCDHGA10 PCDHGA9 PCDHGA5 PCDHGA4 PCDHGA2 PCDHGA1 PCDHGA12 PCDHGA8	9.25e-11	37	123	8	PF15974
Domain	Cadherin_CBD	PCDHGA10 PCDHGA9 PCDHGA5 PCDHGA4 PCDHGA2 PCDHGA1 PCDHGA12 PCDHGA8	9.25e-11	37	123	8	IPR031904
Domain	Cadherin_C	PCDHGA10 PCDHGA9 PCDHGA5 PCDHGA4 PCDHGA2 PCDHGA1 PCDHGA12 PCDHGA8	2.75e-10	42	123	8	IPR032455
Domain	Cadherin_C_2	PCDHGA10 PCDHGA9 PCDHGA5 PCDHGA4 PCDHGA2 PCDHGA1 PCDHGA12 PCDHGA8	2.75e-10	42	123	8	PF16492
Domain	Cadherin_2	PCDHGA10 PCDHGA9 PCDHGA5 PCDHGA4 PCDHGA2 PCDHGA1 PCDHGA12 PCDHGA8	1.04e-08	65	123	8	PF08266
Domain	Cadherin_N	PCDHGA10 PCDHGA9 PCDHGA5 PCDHGA4 PCDHGA2 PCDHGA1 PCDHGA12 PCDHGA8	1.04e-08	65	123	8	IPR013164
Domain	Cadherin_CS	PCDHGA10 PCDHGA9 PCDHGA5 PCDHGA4 PCDHGA2 PCDHGA1 PCDHGA12 PCDHGA8	6.13e-07	109	123	8	IPR020894
Domain	CADHERIN_1	PCDHGA10 PCDHGA9 PCDHGA5 PCDHGA4 PCDHGA2 PCDHGA1 PCDHGA12 PCDHGA8	8.08e-07	113	123	8	PS00232
Domain	Cadherin	PCDHGA10 PCDHGA9 PCDHGA5 PCDHGA4 PCDHGA2 PCDHGA1 PCDHGA12 PCDHGA8	8.08e-07	113	123	8	PF00028
Domain	CADHERIN_2	PCDHGA10 PCDHGA9 PCDHGA5 PCDHGA4 PCDHGA2 PCDHGA1 PCDHGA12 PCDHGA8	8.64e-07	114	123	8	PS50268
Domain	-	PCDHGA10 PCDHGA9 PCDHGA5 PCDHGA4 PCDHGA2 PCDHGA1 PCDHGA12 PCDHGA8	8.64e-07	114	123	8	2.60.40.60
Domain	CA	PCDHGA10 PCDHGA9 PCDHGA5 PCDHGA4 PCDHGA2 PCDHGA1 PCDHGA12 PCDHGA8	9.24e-07	115	123	8	SM00112
Domain	Cadherin-like	PCDHGA10 PCDHGA9 PCDHGA5 PCDHGA4 PCDHGA2 PCDHGA1 PCDHGA12 PCDHGA8	9.87e-07	116	123	8	IPR015919
Domain	Cadherin	PCDHGA10 PCDHGA9 PCDHGA5 PCDHGA4 PCDHGA2 PCDHGA1 PCDHGA12 PCDHGA8	1.12e-06	118	123	8	IPR002126
Domain	Aldehyde_DH_NAD(P)	ALDH3A1 ALDH3A2	2.56e-04	4	123	2	IPR012394
Domain	ICAM	ICAM3 ICAM5	2.56e-04	4	123	2	IPR003988
Domain	ARM-like	NCAPD3 MROH2A DOCK10 HUWE1 TRRAP MROH2B RIPOR1 CAB39L	4.23e-04	270	123	8	IPR011989
Domain	Laminin_domII	LAMA3 LAMA5	4.25e-04	5	123	2	IPR010307
Domain	ICAM_N	ICAM3 ICAM5	4.25e-04	5	123	2	PF03921
Domain	Laminin_aI	LAMA3 LAMA5	4.25e-04	5	123	2	IPR009254
Domain	ICAM_N	ICAM3 ICAM5	4.25e-04	5	123	2	IPR013768
Domain	Laminin_I	LAMA3 LAMA5	4.25e-04	5	123	2	PF06008
Domain	Laminin_II	LAMA3 LAMA5	4.25e-04	5	123	2	PF06009
Domain	ICAM_VCAM_N	ICAM3 ICAM5	6.34e-04	6	123	2	IPR003987
Domain	Ion_trans_dom	CACNA1E SCN1A KCNQ3 KCNS1 TRPV5	9.46e-04	114	123	5	IPR005821
Domain	Ion_trans	CACNA1E SCN1A KCNQ3 KCNS1 TRPV5	9.46e-04	114	123	5	PF00520
Domain	LAMININ_IVA	LAMA3 LAMA5	1.17e-03	8	123	2	PS51115
Domain	Laminin_B	LAMA3 LAMA5	1.17e-03	8	123	2	PF00052
Domain	LamB	LAMA3 LAMA5	1.17e-03	8	123	2	SM00281
Domain	Laminin_IV	LAMA3 LAMA5	1.17e-03	8	123	2	IPR000034
Domain	Transglut_N	TGM7 EPB42	1.50e-03	9	123	2	PF00868
Domain	TRANSGLUTAMINASES	TGM7 EPB42	1.50e-03	9	123	2	PS00547
Domain	-	TGM7 EPB42	1.50e-03	9	123	2	3.90.260.10
Domain	Gln_gamma-glutamylTfrase_euk	TGM7 EPB42	1.50e-03	9	123	2	IPR023608
Domain	Transglutaminase_AS	TGM7 EPB42	1.50e-03	9	123	2	IPR013808
Domain	Transglutaminase_N	TGM7 EPB42	1.50e-03	9	123	2	IPR001102
Domain	Transglut_C	TGM7 EPB42	1.50e-03	9	123	2	PF00927
Domain	ARM-type_fold	NCAPD3 NBEAL1 MROH2A HUWE1 TRRAP MROH2B RIPOR1 CAB39L	1.83e-03	339	123	8	IPR016024
Domain	Transglutaminase_C	TGM7 EPB42	1.87e-03	10	123	2	IPR008958
Domain	Transglutaminase-like	TGM7 EPB42	2.28e-03	11	123	2	IPR002931
Domain	TGc	TGM7 EPB42	2.28e-03	11	123	2	SM00460
Domain	Transglut_core	TGM7 EPB42	2.28e-03	11	123	2	PF01841
Domain	Laminin_N	LAMA3 LAMA5	4.86e-03	16	123	2	IPR008211
Domain	LamNT	LAMA3 LAMA5	4.86e-03	16	123	2	SM00136
Domain	LAMININ_NTER	LAMA3 LAMA5	4.86e-03	16	123	2	PS51117
Domain	Laminin_N	LAMA3 LAMA5	4.86e-03	16	123	2	PF00055
Domain	Ald_DH_CS_GLU	ALDH3A1 ALDH3A2	4.86e-03	16	123	2	IPR029510
Domain	Ald_DH_CS_CYS	ALDH3A1 ALDH3A2	5.48e-03	17	123	2	IPR016160
Domain	ALDEHYDE_DEHYDR_CYS	ALDH3A1 ALDH3A2	6.14e-03	18	123	2	PS00070
Domain	ALDEHYDE_DEHYDR_GLU	ALDH3A1 ALDH3A2	6.14e-03	18	123	2	PS00687
Domain	Channel_four-helix_dom	CACNA1E SCN1A KCNS1	6.30e-03	57	123	3	IPR027359
Domain	-	CACNA1E SCN1A KCNS1	6.30e-03	57	123	3	1.20.120.350
Pubmed	Comparative DNA sequence analysis of mouse and human protocadherin gene clusters.	PCDHGA10 PCDHGA9 PCDHGA5 PCDHGA4 PCDHGA2 PCDHGA1 PCDHGA12 PCDHGA8	2.00e-10	68	131	8	11230163
Pubmed	A striking organization of a large family of human neural cadherin-like cell adhesion genes.	PCDHGA10 PCDHGA9 PCDHGA5 PCDHGA4 PCDHGA2 PCDHGA1 PCDHGA12 PCDHGA8	3.19e-10	72	131	8	10380929
Pubmed	Cadherin superfamily genes: functions, genomic organization, and neurologic diversity.	PCDHGA10 PCDHGA9 PCDHGA5 PCDHGA4 PCDHGA2 PCDHGA1 PCDHGA12 PCDHGA8	3.99e-10	74	131	8	10817752
Pubmed	Phylogenetic analysis of the cadherin superfamily allows identification of six major subfamilies besides several solitary members.	PCDHGA10 PCDHGA9 PCDHGA5 PCDHGA4 PCDHGA2 PCDHGA1 PCDHGA12 PCDHGA8	5.52e-10	77	131	8	10835267
Pubmed	Large exons encoding multiple ectodomains are a characteristic feature of protocadherin genes.	PCDHGA10 PCDHGA9 PCDHGA5 PCDHGA4 PCDHGA2 PCDHGA1 PCDHGA12 PCDHGA8	7.54e-10	80	131	8	10716726
Pubmed	Maturation of postnatally generated olfactory bulb granule cells depends on functional γ-protocadherin expression.	PCDHGA10 PCDHGA9 PCDHGA4 PCDHGA12	2.54e-07	15	131	4	23515096
Pubmed	Interaction with protocadherin-gamma regulates the cell surface expression of protocadherin-alpha.	PCDHGA10 PCDHGA9 PCDHGA4 PCDHGA12	3.67e-06	28	131	4	15347688
Pubmed	Functional significance of isoform diversification in the protocadherin gamma gene cluster.	PCDHGA10 PCDHGA9 PCDHGA4 PCDHGA12	8.17e-06	34	131	4	22884324
Pubmed	A high-density association screen of 155 ion transport genes for involvement with common migraine.	CACNA1E KCNK12 KCNQ3	1.12e-05	12	131	3	18676988
Pubmed	Genomic organization and expression of the human fatty aldehyde dehydrogenase gene (FALDH).	ALDH3A1 ALDH3A2	1.41e-05	2	131	2	9027499
Pubmed	Mitochondrial Regulation of the Hippocampal Firing Rate Set Point and Seizure Susceptibility.	SCN1A DHODH	1.41e-05	2	131	2	31047779
Pubmed	Mouse germ cell-less as an essential component for nuclear integrity.	GMCL1 GMCL2	1.41e-05	2	131	2	12556490
Pubmed	Negative regulation of the murine cytosolic aldehyde dehydrogenase-3 (Aldh-3c) gene by functional CYP1A1 and CYP1A2 proteins.	ALDH3A1 ALDH3A2	1.41e-05	2	131	2	1520328
Pubmed	Molecular evolution of the CYP2D subfamily in primates: purifying selection on substrate recognition sites without the frequent or long-tract gene conversion.	CYP2D7 CYP2D6	1.41e-05	2	131	2	25808902
Pubmed	Polymorphisms in CYP2D6 duplication-negative individuals with the ultrarapid metabolizer phenotype: a role for the CYP2D6*35 allele in ultrarapid metabolism?	CYP2D7 CYP2D6	1.41e-05	2	131	2	11207030
Pubmed	Characterization of the common genetic defect in humans deficient in debrisoquine metabolism.	CYP2D7 CYP2D6	1.41e-05	2	131	2	3123997
Pubmed	Molecular cloning and genomic organization of mouse homologue of Drosophila germ cell-less and its expression in germ lineage cells.	GMCL1 GMCL2	1.41e-05	2	131	2	10448096
Pubmed	Arginine transport in human erythroid cells: discrimination of CAT1 and 4F2hc/y+LAT2 roles.	SLC7A6 SLC3A2	1.41e-05	2	131	2	19562367
Pubmed	Characterization of Cyp2d22, a novel cytochrome P450 expressed in mouse mammary cells.	CYP2D7 CYP2D6	1.41e-05	2	131	2	11032406
Pubmed	Apoptotic cell-derived ICAM-3 promotes both macrophage chemoattraction to and tethering of apoptotic cells.	ICAM3 ICAM5	1.41e-05	2	131	2	22117198
Pubmed	In situ-RT-PCR and immunohistochemistry for the localisation of the mRNA of the alpha 3 chain of laminin and laminin-5 during human organogenesis.	LAMA3 LAMA5	1.41e-05	2	131	2	12382139
Pubmed	Biological function of laminin-5 and pathogenic impact of its deficiency.	LAMA3 LAMA5	1.41e-05	2	131	2	17000025
Pubmed	Mutation of the 4F2 heavy-chain carboxy terminus causes y+ LAT2 light-chain dysfunction.	SLC7A6 SLC3A2	1.41e-05	2	131	2	16785209
Pubmed	The expression of CYP2D22, an ortholog of human CYP2D6, in mouse striatum and its modulation in 1-methyl 4-phenyl-1,2,3,6-tetrahydropyridine-induced Parkinson's disease phenotype and nicotine-mediated neuroprotection.	CYP2D7 CYP2D6	1.41e-05	2	131	2	19594327
Pubmed	Coding-noncoding gene expression in intrahepatic cholangiocarcinoma.	CYP2D7 CYP2D6	1.41e-05	2	131	2	26297049
Pubmed	Stage-specific expression of mouse germ cell-less-1 (mGCL-1), and multiple deformations during mgcl-1 deficient spermatogenesis leading to reduced fertility.	GMCL1 GMCL2	1.41e-05	2	131	2	15700541
Pubmed	A frameshift mutation and alternate splicing in human brain generate a functional form of the pseudogene cytochrome P4502D7 that demethylates codeine to morphine.	CYP2D7 CYP2D6	1.41e-05	2	131	2	15051713
Pubmed	Large-scale analysis of ion channel gene expression in the mouse heart during perinatal development.	CACNA1E KCNK12 CLCN5 SCN1A KCNQ3 KCNS1	1.52e-05	139	131	6	16985003
Pubmed	A differential developmental pattern of spinal interneuron apoptosis during synaptogenesis: insights from genetic analyses of the protocadherin-gamma gene cluster.	PCDHGA10 PCDHGA9 PCDHGA4 PCDHGA12	2.32e-05	44	131	4	19029045
Pubmed	DNA replication in eukaryotic cells.	POLE ORC2 CDT1	4.09e-05	18	131	3	12045100
Pubmed	Sodium and potassium channel dysfunctions in rare and common idiopathic epilepsy syndromes.	SCN1A KCNQ3	4.21e-05	3	131	2	19464834
Pubmed	Chromosome-associated protein D3 promotes bacterial clearance in human intestinal epithelial cells by repressing expression of amino acid transporters.	NCAPD3 SLC3A2	4.21e-05	3	131	2	25701737
Pubmed	Globular domains 4/5 of the laminin alpha3 chain mediate deposition of precursor laminin 5.	LAMA3 LAMA5	4.21e-05	3	131	2	15316072
Pubmed	The human debrisoquine 4-hydroxylase (CYP2D) locus: sequence and identification of the polymorphic CYP2D6 gene, a related gene, and a pseudogene.	CYP2D7 CYP2D6	4.21e-05	3	131	2	2574001
Pubmed	Integration of a growth-suppressing BTB/POZ domain protein with the DP component of the E2F transcription factor.	GMCL1 GMCL2	4.21e-05	3	131	2	9878064
Pubmed	The heterodimeric amino acid transporter 4F2hc/y+LAT2 mediates arginine efflux in exchange with glutamine.	SLC7A6 SLC3A2	4.21e-05	3	131	2	10903140
Pubmed	Cross-regulation of defective endolysosome trafficking and enhanced autophagy through TFEB in UNC13D deficiency.	UNC13D CTNS	4.21e-05	3	131	2	30892133
Pubmed	HUWE1 controls MCL1 stability to unleash AMBRA1-induced mitophagy.	AMBRA1 HUWE1	4.21e-05	3	131	2	31434979
Pubmed	Identification of the primary gene defect at the cytochrome P450 CYP2D locus.	CYP2D7 CYP2D6	4.21e-05	3	131	2	1978251
Pubmed	Clustered gamma-protocadherins regulate cortical interneuron programmed cell death.	PCDHGA10 PCDHGA9 PCDHGA4 PCDHGA12	6.51e-05	57	131	4	32633719
Pubmed	KAP1 facilitates reinstatement of heterochromatin after DNA replication.	NCAPD3 POLE TRMT1 HUWE1 PRPF8 TRRAP MSH6 FDXR DCTN4 DDX39A STOML2	7.63e-05	704	131	11	29955894
Pubmed	Association of IFIH1 and other autoimmunity risk alleles with selective IgA deficiency.	AMBRA1 LINGO2 HARBI1	7.63e-05	22	131	3	20694011
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	POLE COX6A1 TRMT1 LAMA5 AMBRA1 CHD8 CEP192 HUWE1 TRRAP JAK3 RIPOR1 GPC2 SLC45A1 MVB12B	7.65e-05	1105	131	14	35748872
Pubmed	Aldehyde dehydrogenase is a positional marker in the retina.	ALDH3A1 ALDH3A2	8.41e-05	4	131	2	1935685
Pubmed	Human mast cells adhere to and migrate on epithelial and vascular basement membrane laminins LM-332 and LM-511 via alpha3beta1 integrin.	LAMA3 LAMA5	8.41e-05	4	131	2	19752234
Pubmed	A gene for susceptibility to small intestinal cancer, ssic1, maps to the distal part of mouse chromosome 4.	ALDH3A1 ALDH3A2	8.41e-05	4	131	2	7606739
Pubmed	A novel renal carbonic anhydrase type III plays a role in proximal tubule dysfunction.	CLCN5 CTNS	8.41e-05	4	131	2	18322545
Pubmed	TRRAP-dependent and TRRAP-independent transcriptional activation by Myc family oncoproteins.	TRRAP TERT	8.41e-05	4	131	2	12077335
Pubmed	Localization of laminin-5, HD1/plectin, and BP230 in the submandibular glands of developing and adult mice.	LAMA3 LAMA5	8.41e-05	4	131	2	10651091
Pubmed	Apolipoprotein M modulates erythrocyte efflux and tubular reabsorption of sphingosine-1-phosphate.	CLCN5 CTNS	8.41e-05	4	131	2	24950692
Pubmed	Cftr and ENaC ion channels mediate NaCl absorption in the mouse submandibular gland.	CFTR SLC9A2	8.41e-05	4	131	2	20026617
Pubmed	Amino acid transport of y+L-type by heterodimers of 4F2hc/CD98 and members of the glycoprotein-associated amino acid transporter family.	SLC7A6 SLC3A2	8.41e-05	4	131	2	9878049
Pubmed	Identification and characterization of FAM124B as a novel component of a CHD7 and CHD8 containing complex.	CHD8 MVB12B	8.41e-05	4	131	2	23285124
Pubmed	The intercellular adhesion molecule (ICAM) family of proteins. New members and novel functions.	ICAM3 ICAM5	8.41e-05	4	131	2	9638475
Pubmed	A novel serine-rich motif in the intercellular adhesion molecule 3 is critical for its ezrin/radixin/moesin-directed subcellular targeting.	ICAM3 ICAM5	8.41e-05	4	131	2	11784723
Pubmed	Enhanced degradation of MDM2 by a nuclear envelope component, mouse germ cell-less.	GMCL1 GMCL2	8.41e-05	4	131	2	12927808
Pubmed	Mouse microsomal Class 3 aldehyde dehydrogenase: AHD3 cDNA sequence, inducibility by dioxin and clofibrate, and genetic mapping.	ALDH3A1 ALDH3A2	8.41e-05	4	131	2	8634152
Pubmed	Ornithine transport via cationic amino acid transporter-1 is involved in ornithine cytotoxicity in retinal pigment epithelial cells.	SLC7A6 SLC3A2	8.41e-05	4	131	2	17197568
Pubmed	Association of 4F2hc with light chains LAT1, LAT2 or y+LAT2 requires different domains.	SLC7A6 SLC3A2	8.41e-05	4	131	2	11311135
Pubmed	Identification and characterization of a membrane protein (y+L amino acid transporter-1) that associates with 4F2hc to encode the amino acid transport activity y+L. A candidate gene for lysinuric protein intolerance.	SLC7A6 SLC3A2	8.41e-05	4	131	2	9829974
Pubmed	Mouse aldehyde dehydrogenase ALDH3B2 is localized to lipid droplets via two C-terminal tryptophan residues and lipid modification.	ALDH3A1 ALDH3A2	8.41e-05	4	131	2	25286108
Pubmed	In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.	GABRG1 CACNA1E NHSL2 PCDHGA10 PCDHGA9 PCDHGA5 PCDHGA4 PCDHGA2 PCDHGA1 PRPF8 SLC3A2 CLCN5 PCDHGA12 LMLN DDX39A PCDHGA8	1.09e-04	1442	131	16	35575683
Pubmed	Expression and distribution of laminin alpha1 and alpha2 chains in embryonic and adult mouse tissues: an immunochemical approach.	LAMA3 LAMA5	1.40e-04	5	131	2	11969289
Pubmed	Differential expression of five laminin alpha (1-5) chains in developing and adult mouse kidney.	LAMA3 LAMA5	1.40e-04	5	131	2	9415429
Pubmed	Differential expression of laminin alpha chains during murine tooth development.	LAMA3 LAMA5	1.40e-04	5	131	2	9389447
Pubmed	Activated apoptotic cells induce dendritic cell maturation via engagement of Toll-like receptor 4 (TLR4), dendritic cell-specific intercellular adhesion molecule 3 (ICAM-3)-grabbing nonintegrin (DC-SIGN), and β2 integrins.	ICAM3 ICAM5	1.40e-04	5	131	2	22396536
Pubmed	Complete sequence, recombinant analysis and binding to laminins and sulphated ligands of the N-terminal domains of laminin alpha3B and alpha5 chains.	LAMA3 LAMA5	1.40e-04	5	131	2	11829758
Pubmed	Identification of new ciliary signaling pathways in the brain and insights into neurological disorders.	CACNA1E PCDHGA4 LINGO2 BRINP1 SLC3A2 SCN1A KCNQ3 RIPOR1	1.57e-04	405	131	8	38187761
Pubmed	HIV-protein-mediated alterations in T cell interactions with the extracellular matrix proteins and endothelium.	LAMA3 LAMA5	2.09e-04	6	131	2	9597096
Pubmed	Lessons from genetically engineered animal models VIII. Absorption and secretion of ions in the gastrointestinal tract.	CFTR SLC9A2	2.09e-04	6	131	2	10666041
Pubmed	Identification of a mouse germ cell-less homologue with conserved activity in Drosophila.	GMCL1 GMCL2	2.09e-04	6	131	2	10727854
Pubmed	Genetic mapping refines DFNB3 to 17p11.2, suggests multiple alleles of DFNB3, and supports homology to the mouse model shaker-2.	ALDH3A1 ALDH3A2	2.09e-04	6	131	2	9529344
Pubmed	Polymorphism of metabolic genes and susceptibility to occupational chronic manganism.	CYP2D7 CYP2D6	2.09e-04	6	131	2	12171760
Pubmed	Discovery and Characterization of ZUFSP/ZUP1, a Distinct Deubiquitinase Class Important for Genome Stability.	NCAPD3 POLE KIF7 MSH6 VPS52	2.44e-04	147	131	5	29576527
Pubmed	Identification of SUMO Binding Proteins Enriched after Covalent Photo-Cross-Linking.	NCAPD3 GAPVD1 CHD8 HUWE1 PRPF8 MSH6 DDX39A	2.75e-04	332	131	7	32786267
Pubmed	C9orf72 protein quality control by UBR5-mediated heterotypic ubiquitin chains.	NCAPD3 POLE TRMT1 AMBRA1 HUWE1 PRPF8 TRAPPC1 SLC3A2 MSH6 GMDS DCTN4 ALDH3A2 DDX39A STOML2	2.90e-04	1257	131	14	37317656
Pubmed	Human ING1 proteins differentially regulate histone acetylation.	ING1 TRRAP	2.92e-04	7	131	2	12015309
Pubmed	Differential expression of individual gamma-protocadherins during mouse brain development.	PCDHGA4 PCDHGA12	2.92e-04	7	131	2	15964765
Pubmed	Evolution of transglutaminase genes: identification of a transglutaminase gene cluster on human chromosome 15q15. Structure of the gene encoding transglutaminase X and a novel gene family member, transglutaminase Z.	TGM7 EPB42	2.92e-04	7	131	2	11390390
Pubmed	Laminins promote the locomotion of skeletal myoblasts via the alpha 7 integrin receptor.	LAMA3 ITGA7	2.92e-04	7	131	2	9004048
Pubmed	SPOP mutation induces replication over-firing by impairing Geminin ubiquitination and triggers replication catastrophe upon ATR inhibition.	ORC2 CDT1	2.92e-04	7	131	2	34599168
Pubmed	Effects of infection of MRSA on the expression and activity of renal cytochrome P450s in mice.	CYP2D7 CYP2D6	2.92e-04	7	131	2	30944282
Pubmed	Systematic Affinity Purification Coupled to Mass Spectrometry Identified p62 as Part of the Cannabinoid Receptor CB2 Interactome.	HECTD3 HUWE1 SLC3A2 ALDH3A2	2.94e-04	84	131	4	31616248
Pubmed	Ion channel expression in the developing enteric nervous system.	CLCN5 KCNQ3 KCNS1	3.69e-04	37	131	3	25798587
Pubmed	Expression and localization of laminin-5 subunits during mouse tooth development.	LAMA3 LAMA5	3.88e-04	8	131	2	9489770
Pubmed	Cloning and expression analyses of mouse dystroglycan gene: specific expression in maternal decidua at the peri-implantation stage.	LAMA3 LAMA5	3.88e-04	8	131	2	8872465
Pubmed	Spatial and temporal control of laminin-332 and -511 expressions during hair morphogenesis.	LAMA3 LAMA5	3.88e-04	8	131	2	23529140
Pubmed	Defective CFTR induces aggresome formation and lung inflammation in cystic fibrosis through ROS-mediated autophagy inhibition.	CFTR AMBRA1	3.88e-04	8	131	2	20711182
Pubmed	Roles for laminin in embryogenesis: exencephaly, syndactyly, and placentopathy in mice lacking the laminin alpha5 chain.	LAMA3 LAMA5	3.88e-04	8	131	2	9852162
Pubmed	A WD-repeat protein stabilizes ORC binding to chromatin.	ORC2 CDT1	3.88e-04	8	131	2	20932478
Pubmed	Genome-wide association study of d-amphetamine response in healthy volunteers identifies putative associations, including cadherin 13 (CDH13).	WWOX CSMD2 SCN1A	4.00e-04	38	131	3	22952603
Pubmed	Proteomic analyses reveal distinct chromatin-associated and soluble transcription factor complexes.	NCAPD3 GAPVD1 ING1 POLE HUWE1 PRPF8 TRRAP KIF7 ORC2 ASMTL DDX39A	4.15e-04	857	131	11	25609649
Pubmed	Dynamic Protein Interactions of the Polycomb Repressive Complex 2 during Differentiation of Pluripotent Cells.	ING1 POLE CEP290 CHD8 HUWE1 TRRAP ORC2 CDT1	4.20e-04	469	131	8	27634302
Pubmed	Functional expression of the new gap junction gene connexin47 transcribed in mouse brain and spinal cord neurons.	ALDH3A1 ALDH3A2	4.98e-04	9	131	2	11160382
Pubmed	Metabolic activation-related CD147-CD98 complex.	SLC7A6 SLC3A2	4.98e-04	9	131	2	15901826
Pubmed	Familial pure proximal renal tubular acidosis--a clinical and genetic study.	SLC26A1 SLC9A2	4.98e-04	9	131	2	17881426
Pubmed	ALS/FTD-causing mutation in cyclin F causes the dysregulation of SFPQ.	TRMT1 AMBRA1 CHD8 HUWE1 PRPF8 SLC3A2 CDT1 STOML2 UQCRFS1P1	6.19e-04	624	131	9	33729478
Pubmed	Genes associated with immunoglobulin V(D)J recombination are linked on mouse chromosome 2 and human chromosome 11.	ALDH3A1 ALDH3A2	6.21e-04	10	131	2	8093609
Pubmed	Inhibition of eukaryotic DNA replication by geminin binding to Cdt1.	ORC2 CDT1	6.21e-04	10	131	2	11125146
Pubmed	Integrin-laminin interactions controlling neurite outgrowth from adult DRG neurons in vitro.	LAMA5 ITGA7	6.21e-04	10	131	2	18590826
Interaction	PCDHGA8 interactions	PCDHGA9 PCDHGA5 PCDHGA4 PCDHGA8	6.79e-09	5	124	4	int:PCDHGA8
Interaction	PCDHGA4 interactions	PCDHGA10 PCDHGA9 PCDHGA5 PCDHGA4 PCDHGA12 PCDHGA8	5.61e-08	34	124	6	int:PCDHGA4
Interaction	ZUP1 interactions	NCAPD3 POLE CFTR AMBRA1 HUWE1 PRPF8 KIF7 MSH6 VPS52	1.31e-06	174	124	9	int:ZUP1
Interaction	PCDHGA9 interactions	PCDHGA9 PCDHGA5 PCDHGA4 PCDHGA12 PCDHGA8	1.68e-06	33	124	5	int:PCDHGA9
Interaction	H2BC5 interactions	PCDHGA10 PCDHGA9 PCDHGA5 PCDHGA4 PCDHGA2 PCDHGA1 HUWE1 PRPF8 MSH6 PCDHGA12 PCDHGA8	6.45e-06	331	124	11	int:H2BC5
Interaction	PCDHGA7 interactions	PCDHGA10 PCDHGA5 PCDHGA4 PCDHGA12	1.56e-05	25	124	4	int:PCDHGA7
Interaction	KPNA2 interactions	GAPVD1 ING1 MROH2A CFTR CHD8 HUWE1 PRPF8 TRRAP GMCL1 MSH6 CDT1 DCTN4 BRD1	1.91e-05	519	124	13	int:KPNA2
Interaction	PCDHGA12 interactions	PCDHGA9 PCDHGA4 PCDHGA12	2.64e-05	10	124	3	int:PCDHGA12
Interaction	PCDHA9 interactions	PCDHGA10 PCDHGA9 PCDHGA4 PCDHGA12	4.30e-05	32	124	4	int:PCDHA9
Interaction	PCDHGA5 interactions	PCDHGA9 PCDHGA5 PCDHGA4 ITGA7 PCDHGA8	4.30e-05	63	124	5	int:PCDHGA5
Interaction	SPTLC1 interactions	WWOX CFTR AMBRA1 TRRAP JAK3 BRD1 ALDH3A2	5.80e-05	159	124	7	int:SPTLC1
Interaction	EMG1 interactions	CFTR CEP290 NAA80 LINGO2 PRPF8 TRRAP	7.10e-05	113	124	6	int:EMG1
Interaction	ITGAL interactions	ICAM3 ICAM5 DDX39A	7.88e-05	14	124	3	int:ITGAL
Interaction	BRINP1 interactions	BRINP1 TRRAP ORC2 MSH6	8.57e-05	38	124	4	int:BRINP1
Interaction	LLCFC1 interactions	INHBE CFTR LAMA3 LAMA5 ITGA7 LMLN	1.04e-04	121	124	6	int:LLCFC1
Cytoband	5q31	PCDHGA10 PCDHGA9 PCDHGA5 PCDHGA4 PCDHGA2 PCDHGA1 PCDHGA12 PCDHGA8	1.72e-09	115	132	8	5q31
Cytoband	Ensembl 112 genes in cytogenetic band chr5q31	PCDHGA10 PCDHGA9 PCDHGA5 PCDHGA4 PCDHGA2 PCDHGA1 PCDHGA12 FNIP1 PCDHGA8	2.29e-07	298	132	9	chr5q31
GeneFamily	Clustered protocadherins	PCDHGA10 PCDHGA9 PCDHGA5 PCDHGA4 PCDHGA2 PCDHGA1 PCDHGA12 PCDHGA8	8.84e-10	64	89	8	20
GeneFamily	Transglutaminases	TGM7 EPB42	8.43e-04	9	89	2	773
GeneFamily	Maestro heat like repeat containing	MROH2A MROH2B	1.28e-03	11	89	2	636
GeneFamily	Laminin subunits	LAMA3 LAMA5	1.53e-03	12	89	2	626
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Degenerative_Podocyte\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	KIRREL2 TENM2 WT1-AS GMDS RIPOR1 SLC45A1 ARHGEF26	1.10e-06	182	130	7	cde8fa4f42d25545abaa9ee885b4b1e24a5a8e08
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	KIRREL2 TENM2 WT1-AS GMDS RIPOR1 SLC45A1 ARHGEF26	1.27e-06	186	130	7	1094c7140131454b2583200e1c01e81ccab3db23
ToppCell	Primary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_C_(IT_L4_RORB)\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	LAMA3 LINGO2 BRINP1 CSMD2 TENM2 SCN1A KCNS1	1.46e-06	190	130	7	1bbbf0ce222e51f9fd2daca0c18d3965fd4efd31
ToppCell	kidney_cells-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Degenerative_Podocyte\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	KIRREL2 TENM2 WT1-AS GMDS RIPOR1 SLC45A1 ARHGEF26	1.57e-06	192	130	7	ef0aba777072429a6ab7dcfcc305673975946580
ToppCell	Primary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_C_(IT_L4_RORB)-Exc_L4_RORB_BHLHE22\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	LAMA3 LINGO2 BRINP1 CSMD2 TENM2 KCNS1 ARHGEF26	1.57e-06	192	130	7	25460ca9ebd3d49f666394cf99ab77a5e8f77250
ToppCell	LPS_anti-TNF-Epithelial_alveolar-AT_1-Differentiating_AT1\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	NBEAL1 LAMA3 UNC13D ANKRD6 ICAM5 ARHGEF26 ALPI	1.99e-06	199	130	7	d43c605a4ff221cf78d91678c15d2ad20f831c7f
ToppCell	E16.5-Endothelial-Endothelial_lymphatic\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CACNA1E ADGRG3 MFSD4A ANKRD6 RIPOR1 BRSK1	9.74e-06	167	130	6	b93103a868fba63a8910bffb690a6242b9252833
ToppCell	E16.5-Endothelial-Endothelial_lymphatic-Lymphatic_EC-LEC\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CACNA1E ADGRG3 MFSD4A ANKRD6 RIPOR1 BRSK1	9.74e-06	167	130	6	fcd583b1efd0ac883379982ea8e6c54f2c0be268
ToppCell	E16.5-Endothelial-Endothelial_lymphatic-Lymphatic_EC\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CACNA1E ADGRG3 MFSD4A ANKRD6 RIPOR1 BRSK1	9.74e-06	167	130	6	f6bc63138b7239211fa5f27a8dc799b6e022c0f8
ToppCell	E16.5-Endothelial-Endothelial_lymphatic-Lymphatic_EC-LEC-LEC_mature\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CACNA1E ADGRG3 MFSD4A ANKRD6 RIPOR1 BRSK1	9.74e-06	167	130	6	26cd8ee5e826e71eaf58d10a906543a6932fb3f9
ToppCell	390C-Epithelial_cells-Epithelial-I_(AT1)\|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)	LAMA3 LAMA5 UNC13D FDXR ARHGEF26 MVB12B	1.04e-05	169	130	6	665b958f4a720ca369a8a0abc7fbe8b6e13c8ce5
ToppCell	390C-Epithelial_cells-Epithelial-I_(AT1)-\|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)	LAMA3 LAMA5 UNC13D FDXR ARHGEF26 MVB12B	1.04e-05	169	130	6	6614c9851537e4c21b1e45ff0cc3bad07ef9d034
ToppCell	BALF-PFMC-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c08-IL2RB\|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)	ADGRG3 POLE ICAM3 SH2D3C KCNK12 JAK3	1.45e-05	179	130	6	db76edd368eeca05a2a5d407c3eb2f535ade0ce3
ToppCell	COVID-19-lung-AT1\|COVID-19 / Disease (COVID-19 only), tissue and cell type	LAMA3 LAMA5 UNC13D KCNQ3 ALDH3A2 ARHGEF26	1.64e-05	183	130	6	7b1a385ed54f93bfe85bf0c162e42d05d516b45c
ToppCell	Smart-start-Cell-Wel_seq-Neoplastic-Differentiated-like-AC-like-AC-like-C\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	PCDHGA10 PCDHGA9 PCDHGA4 PCDHGA2 PCDHGA1 ASMTL	1.69e-05	184	130	6	629cfed10e1112cf30f6a828ce9efbbc6b207789
ToppCell	Somatosensory_Cortex_(S1)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_C_(IT_L4_RORB)\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	LAMA3 LINGO2 BRINP1 CSMD2 TENM2 KCNS1	1.69e-05	184	130	6	6475a43201b136dcc9b113d2ca4cfa154ed9d65d
ToppCell	kidney_cells-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Podocyte\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	TENM2 WT1-AS GMDS RIPOR1 SLC45A1 ARHGEF26	1.85e-05	187	130	6	24c2a3962da364e46e98abeab5f8234376fa26bb
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Degenerative_Podocyte\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	KIRREL2 TENM2 WT1-AS GMDS RIPOR1 ARHGEF26	1.91e-05	188	130	6	9db778c1d9e622a68337212296e3a1ed8f771fa5
ToppCell	facs-Marrow-KLS-3m-Hematologic-MPP_Fraction_B_+_C\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ADGRG3 KCNK12 TFR2 JAK3 MSH6 RIPOR1	2.15e-05	192	130	6	03dcd9405d3d76fc7455066ba5d83c09cd17072d
ToppCell	kidney_cells-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	TENM2 WT1-AS GMDS RIPOR1 SLC45A1 ARHGEF26	2.21e-05	193	130	6	3eaa0461618582a1754400624350d269d24e750a
ToppCell	Primary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	LINGO2 BRINP1 CSMD2 TENM2 SCN1A KCNS1	2.34e-05	195	130	6	787e95fb59c40bba784544b662fac37606ae1427
ToppCell	Bronchial-NucSeq-Stromal-Fibroblastic-Fibro_myofibroblast\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	ADGRG3 TENM2 KIF7 ARHGAP6 PIEZO2 BRSK1	2.34e-05	195	130	6	f5e91ce20a7ce528dc4c1a968c7bf096bf45c528
ToppCell	Control_saline-Epithelial_alveolar-AT_1-Differentiating_AT1\|Control_saline / Treatment groups by lineage, cell group, cell type	NBEAL1 LAMA3 UNC13D ICAM5 ARHGEF26 ALPI	2.55e-05	198	130	6	85f424cd9bb3117c9e322031024aabb87696ce47
ToppCell	LPS_IL1RA-Epithelial_alveolar-AT_1-Differentiating_AT1\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	NBEAL1 LAMA3 UNC13D ICAM5 ARHGEF26 ALPI	2.55e-05	198	130	6	b598ab958e31f1e98bd06dc0097b58ac3a3f90a3
ToppCell	Smart-start-Cell-Wel_seq-Neoplastic-Differentiated-like-MES-like-MES-like_hypoxia_independent-F\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	FRMD6-AS1 NBEAL1 LAMA5 ITGA7 TFR2 RIPOR1	2.63e-05	199	130	6	85bb28369e0568b7b3bda095722102fc793f60ef
ToppCell	Sepsis-URO\|Sepsis / Disease, condition lineage and cell class	NBEAL1 NHSL2 PCDHGA10 ITGA7 JAK3 BRSK1	2.63e-05	199	130	6	8e6dac82d1d0e759cd567f9c95b70cb4801d7caf
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW12-Mesenchymal-Unfolded_protein_responsible_cell\|GW12 / Sample Type, Dataset, Time_group, and Cell type.	DNAH10 CFTR NAA80 KIRREL2 TFR2 ARHGEF10	2.70e-05	200	130	6	6b7314c425f6b40f1301dd39cc02b0436e96a2ec
ToppCell	Control-PLT_5\|World / Disease Group and Platelet Clusters	NBEAL1 PCDHGA10 TENM2 FAM27D1 ARHGEF10	3.44e-05	126	130	5	4ba753c4e83eb1d41964edfa22135e047f06c481
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_ascending_limb_epithelial_cell-Ascending_Thin_Limb_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	GABRG1 CDC42BPG SCN1A FDXR NECTIN4	4.30e-05	132	130	5	97e7d5f7086c6213aec4eaa581bc182338189029
ToppCell	droplet-Lung-18m-Hematologic-lymphocytic-CD8-positive,_alpha-beta_T_cell-CD8-positive,_alpha-beta_T_cell_l21\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	NCAPD3 PUS3 PRPF8 TRIM56 MTRF1L	7.64e-05	149	130	5	65778f19599b4955c0a16f0121237656449431fb
Drug	amobarbital	GABRG1 CYP2D7 WWOX CYP2D6 DHODH	1.32e-06	34	129	5	CID000002163
Drug	lactofen	PCDHGA10 PCDHGA2 MSH6 PCDHGA12 LMLN PCDHGA8	6.75e-06	81	129	6	CID000062276
Drug	butyraldehyde	WWOX FDXR ALDH3A1 ALDH3A2 ALPI	7.61e-06	48	129	5	CID000000261
Disease	mental development measurement	PCDHGA10 PCDHGA9 PCDHGA5 PCDHGA4 PCDHGA2 PCDHGA1 PCDHGA8	1.10e-11	25	128	7	EFO_0008230
Disease	childhood trauma measurement, alcohol consumption measurement	PCDHGA10 PCDHGA9 PCDHGA5 PCDHGA4 PCDHGA2 PCDHGA1 PCDHGA12 PCDHGA8	8.50e-10	71	128	8	EFO_0007878, EFO_0007979
Disease	Sarcosine measurement	PCDHGA5 PCDHGA4 PCDHGA2 PCDHGA1 PCDHGA8	4.49e-08	23	128	5	EFO_0021668
Disease	mean platelet volume	PCDHGA10 PCDHGA9 PCDHGA5 PCDHGA4 PCDHGA2 PCDHGA1 DOCK10 TRMT1 UNC13D TERT GMCL2 PCDHGA12 KCNS1 RIPOR1 BRD1 ALDH3A2 PCDHGA8	2.11e-06	1020	128	17	EFO_0004584
Disease	solanidine measurement	CYP2D7 CYP2D6	1.11e-04	4	128	2	EFO_0800966
Disease	cancer (implicated_via_orthology)	WWOX ING1 POLE ITGA7 TERT TRAPPC1 CAB39L	1.75e-04	268	128	7	DOID:162 (implicated_via_orthology)
Disease	Sjogren-Larsson syndrome (implicated_via_orthology)	ALDH3A1 ALDH3A2	2.77e-04	6	128	2	DOID:14501 (implicated_via_orthology)
Disease	Large cell carcinoma of lung	TRRAP BRSK1 MAP3K2	3.61e-04	32	128	3	C0345958
Disease	Hereditary spherocytosis	DHODH EPB42	5.14e-04	8	128	2	C0037889
Disease	ovarian cancer (implicated_via_orthology)	POLE MSH6	5.14e-04	8	128	2	DOID:2394 (implicated_via_orthology)
Disease	lymphocyte count	INHBE WWOX DNAH10 PCDHGA10 PCDHGA9 PCDHGA5 PCDHGA4 PCDHGA2 PCDHGA1 ICAM3 DOCK10 TFR2 PCDHGA12 ICAM5 RIPOR1 PCDHGA8	6.13e-04	1464	128	16	EFO_0004587
Disease	Pulmonary Cystic Fibrosis	CFTR DCTN4	6.59e-04	9	128	2	C0392164
Disease	Fibrocystic Disease of Pancreas	CFTR DCTN4	6.59e-04	9	128	2	C1527396
Disease	Intellectual Disability	CACNA1E PUS3 TRMT1 CHD8 TRRAP KIF7 SCN1A ALDH3A2	7.65e-04	447	128	8	C3714756
Disease	cystic kidney disease (implicated_via_orthology)	CEP290 LAMA5	8.21e-04	10	128	2	DOID:2975 (implicated_via_orthology)
Disease	long QT syndrome (implicated_via_orthology)	ARHGAP6 KCNQ3	8.21e-04	10	128	2	DOID:2843 (implicated_via_orthology)
Disease	Adenocarcinoma of large intestine	POLE TRRAP MSH6 TNNI3K	8.25e-04	96	128	4	C1319315
Disease	fibrinogen measurement, plasminogen activator inhibitor 1 measurement	HGFAC TRIM56 FNIP1	9.90e-04	45	128	3	EFO_0004623, EFO_0004792
Disease	Gastric Adenocarcinoma	TRRAP JAK3 BRSK1	9.90e-04	45	128	3	C0278701
Disease	Macrocephaly	CACNA1E CHD8	1.00e-03	11	128	2	C0221355
Disease	Cystic Fibrosis	CFTR DCTN4	1.00e-03	11	128	2	C0010674
Disease	Cooley's anemia	TFR2 DHODH	1.20e-03	12	128	2	C0002875
Disease	Thalassemia Intermedia	TFR2 DHODH	1.20e-03	12	128	2	C0271979
Disease	mismatch repair cancer syndrome (is_implicated_in)	POLE MSH6	1.20e-03	12	128	2	DOID:0112182 (is_implicated_in)
Disease	Thalassemia Minor	TFR2 DHODH	1.20e-03	12	128	2	C0085578
Disease	beta Thalassemia	TFR2 DHODH	1.20e-03	12	128	2	C0005283
Disease	intercellular adhesion molecule 5 measurement	ICAM3 ICAM5	1.41e-03	13	128	2	EFO_0008164
Disease	Leber congenital amaurosis (implicated_via_orthology)	WWOX CEP290	1.41e-03	13	128	2	DOID:14791 (implicated_via_orthology)
Disease	lifestyle measurement, alcohol consumption measurement	BRINP1 CSMD2 PIEZO2 KCNQ3	1.61e-03	115	128	4	EFO_0007878, EFO_0010724
Disease	myelodysplastic syndrome (implicated_via_orthology)	PRPF8 SAMD9L	1.89e-03	15	128	2	DOID:0050908 (implicated_via_orthology)
Disease	Hemoglobin F Disease	TFR2 DHODH	1.89e-03	15	128	2	C0019025
Disease	idiopathic scoliosis (implicated_via_orthology)	DNAH10 KIF7	2.15e-03	16	128	2	DOID:0060250 (implicated_via_orthology)
Disease	Bardet-Biedl syndrome 1 (disorder)	CEP290 KIF7	2.43e-03	17	128	2	C2936862
Disease	coronary artery disease, plasminogen activator inhibitor 1 measurement	NBEAL1 TRIM56 ARHGEF26	2.62e-03	63	128	3	EFO_0001645, EFO_0004792
Disease	Malignant neoplasm of endometrium	POLE MSH6	2.73e-03	18	128	2	C0007103
Disease	squamous cell carcinoma (is_implicated_in)	WWOX ING1	2.73e-03	18	128	2	DOID:1749 (is_implicated_in)
Disease	Carcinoma in situ of endometrium	POLE MSH6	2.73e-03	18	128	2	C0346191
Disease	Global developmental delay	CACNA1E PUS3 TRMT1 TRRAP	2.73e-03	133	128	4	C0557874
Disease	lifestyle measurement, anxiety disorder measurement	BRINP1 CSMD2 PIEZO2 KCNQ3	3.04e-03	137	128	4	EFO_0007795, EFO_0010724
Disease	Chronic myeloproliferative disorder	JAK3 CDT1	3.04e-03	19	128	2	C1292778
Disease	Profound Mental Retardation	TRMT1 CHD8 KIF7 SCN1A	3.20e-03	139	128	4	C0020796
Disease	Mental Retardation, Psychosocial	TRMT1 CHD8 KIF7 SCN1A	3.20e-03	139	128	4	C0025363
Disease	Mental deficiency	TRMT1 CHD8 KIF7 SCN1A	3.20e-03	139	128	4	C0917816
Disease	Familial aplasia of the vermis	CEP290 KIF7	3.37e-03	20	128	2	cv:C0431399
Disease	Nephritis, Tubulointerstitial	CYP2D6 CLCN5	3.71e-03	21	128	2	C0041349
Disease	Alzheimer disease, polygenic risk score	CACNA1E WWOX PCDHGA5 PCDHGA4 PCDHGA2 PCDHGA1 BRD1 EPB42	4.12e-03	586	128	8	EFO_0030082, MONDO_0004975

Protein segments in the cluster

Peptide	Gene	Start	Entry
FNNILRRQIGTRSPT	CAB39L	101	Q9H9S4
LSSRRLFVRRGQPFT	EPB42	26	P16452
SRNGAPLLRRLQSSL	BRD1	486	O95696
FLSRAPSLNRAERGI	ARHGEF10	6	O15013
PGSALTARLRRLVTA	CHD8	1741	Q9HCK8
STGPTLQARRRQSVL	CFTR	756	P13569
NLRTRLTGFQLPATI	CSMD2	91	Q7Z408
RPGTSFGISVLRALR	CACNA1E	561	Q15878
FQRSIRLLGRRPTTQ	BRINP1	101	O60477
RLLGRRPTTQQFIDT	BRINP1	106	O60477
SRTRLPTLLRNETGQ	BRINP1	621	O60477
RSLSSRGFSQPRLLE	ALPK2	1326	Q86TB3
TPGRILALVRNRSFS	DDX39A	171	O00148
IQALLSSRGVRPVSF	FDXR	441	P22570
SSGRTRPLQFRIQQL	ALDH3A1	16	P30838
GAAPQLTASRLLQRR	CDT1	281	Q9H211
SLFRSLPGNRSVVRL	ADGRG3	136	Q86Y34
AFLSGRSRPLRFRLQ	ALDH3A2	11	P51648
TVHRSPLLLGAQRRA	ARHGEF26	76	Q96DR7
NTLRNLSLGPTRRSL	AMBRA1	381	Q9C0C7
KAPQVLRFSRGRSLR	ANKRD6	261	Q9Y2G4
NLRRERGLSTFLFRP	AMPD3	571	Q01432
SGSVSLQPRRSIAFR	GMCL1	441	Q96IK5
SLLRTSPTRGQLFLL	NBEAL1	1116	Q6ZS30
IVSRGRSQLFALNPR	PCDHGA2	66	Q9Y5H1
PSLRDLIQGLSFVTR	JAK3	196	P52333
RRSPTGTFLLVGLSR	JAK3	431	P52333
IVSRGRTQLFALNPR	PCDHGA5	66	Q9Y5G8
RTQLFALNPRSGSLV	PCDHGA5	71	Q9Y5G8
IVSRGRTQLFALNPR	PCDHGA8	66	Q9Y5G5
RTQLFALNPRSGSLV	PCDHGA12	71	O60330
LSSGPLRRERSVAQF	CDC42BPG	36	Q6DT37
RIVSRGRTQLFALNP	PCDHGA4	96	Q9Y5G9
DFQTRSRLLRSGLSP	C19orf81	141	C9J6K1
TNIRLRFLRTNTLLG	LAMA3	256	Q16787
SPRRGANFVTRKISR	GMDS	211	O60547
RVSGLLRRNLQPTLT	MFSD4A	6	Q8N468
FLRRSRQVAEAPGLV	NUDT22	136	Q9BRQ3
GLVFTSRRLPATLLN	NAA80	196	Q93015
FGDSPRRLRLQITRT	GPC2	206	Q8N158
SPRRQEILSNAGLRF	ASMTL	21	O95671
LLDRVRLSNPRGSNT	KCNQ3	426	O43525
GRNFQERLIRSLPTS	FPR3	306	P25089
NPRRLLRRGTCAFSI	GAPVD1	166	Q14C86
FQVRRPAGTILLSRQ	LMLN	131	Q96KR4
ALTRALRRLQPGSVA	INHBE	71	P58166
ELLGANLSRPTQRSR	HARBI1	51	Q96MB7
RTLQARGLIRTFQRP	ICAM5	106	Q9UMF0
ERQLRRSGLLPATFR	KCNK12	181	Q9HB15
IVSRGRTQLFSLNPR	PCDHGA9	66	Q9Y5G4
VSRGRTQLFSLNPRS	PCDHGA10	71	Q9Y5H3
RKTFPRARRTQGTSL	MAP3K2	281	Q9Y2U5
FTVTLEQRGRAPSRL	KIF7	221	Q2M1P5
LGNPLSARALRRLFT	LRRC14B	396	A6NHZ5
TPRRRFITTKSNGRA	LINGO2	446	Q7L985
RQLSARALARFPGTR	KCNS1	61	Q96KK3
ELSLVRTVTRGPRAF	TEPSIN	246	Q96N21
LGSIVFRRNRISSPE	ANKS4B	271	Q8N8V4
GSFLRRTARSILDLP	POLE	1316	Q07864
LPRSSRGLLLFTARL	LAMA5	3371	O15230
VSSVSRLLGRSRPQL	COX6A1	6	P12074
RLTPIDRVFTRLGAS	MSH6	1166	P52701
RTFLRPRIIGGSSSL	HGFAC	401	Q04756
QLSSSLPLQSRGRAR	HUWE1	2591	Q7Z6Z7
RRNRLSFLGAATVEP	ERVK-7	6	P63135
RHISLTLPATFRGRN	MVB12B	221	Q9H7P6
LGLFVNTSAPRQLRT	ICAM3	201	P32942
TEAALRLLSRNPRGF	ALPI	311	P09923
GRSVRLRSVPIQSLS	ARHGAP6	206	O43182
SPARFRVLGTLSNSR	EEF1AKMT4-ECE2	846	P0DPD8
ASRRALQLSGTPVRQ	HTRA3	106	P83110
TRRFTRSLLRPGQAA	DOCK10	6	Q96BY6
PFLLRSQSRGVRLVF	GABRG1	11	Q8N1C3
TIQSLRRQFSGALPL	CEP290	1266	O15078
QRRFSVSTLRNLGLG	CYP2D6	131	P10635
RRAFSEQGPLRLIRS	FNIP1	216	Q8TF40
TLRSINPFGNSRLVL	CLCN5	361	P51795
NSPRGIIFTRTRQSA	DHX58	366	Q96C10
PGSLLSLFRRLSDQR	SLC3A2	516	P08195
LGRLAASAPLRAQVR	EFS	491	O43281
SRLNSIRNSFLGSPR	BRSK1	551	Q8TDC3
APVRLGLRQRAVSSS	FRMD6-AS1	46	P0C7T7
PVLRSVSLRARAGIA	CEP192	1631	Q8TEP8
AQASLGRRDLLPTVR	KIRREL2	496	Q6UWL6
RGQVPRVTFLSRNLE	ITGA7	581	Q13683
SNQTGPRIRFLVIRS	CTNS	106	O60931
AARLLGRLTPTNTVR	FAM27D1	176	Q5T7N8
TRLQRPRAGASISTL	DCTN4	186	Q9UJW0
RVSLRTESLGQPLNR	DNAH10	41	Q8IVF4
CTSRFGRRRPFILVL	SLC45A1	181	Q9Y2W3
ALNPRSGSLITARRI	PCDHGA1	76	Q9Y5H4
GRLQSRLSPRISATS	MROH2A	1196	A6NES4
LRSLTPNARGIFRLL	ORC2	481	Q13416
ARQTLLLASRGFPRD	RTL1	1011	A6NKG5
RSIRFALEVPGLRSV	TRMT1	166	Q9NXH9
QVISLDLRSQFPRGR	PUS3	126	Q9BZE2
FQRARELASRGPSLL	SPATA5L1	286	Q9BVQ7
PKSTLRRRRTIIGFS	NHSL2	276	Q5HYW2
LFTRGGPLRTFLERQ	MTRF1L	36	Q9UGC7
SRRFLPARGSSSVIL	SAMD9L	631	Q8IVG5
PARRQFQAASLLTRG	ING1	166	Q9UK53
SGSVSLRPRRSIAFR	GMCL2	441	Q8NEA9
RLAVRFTSLGLLPRA	DHODH	56	Q02127
VSQPTLLVNGRTRRF	TENM2	2651	Q9NT68
SRLGRSRAVRISQPL	WT1-AS	36	Q06250
PFGIQIRRRSSGRVI	SI	1071	P14410
IGLPRSLRRSIFINL	MROH2B	266	Q7Z745
LLSIRGSLFSPRRNS	SCN1A	556	P35498
SRHRSRSLGVLPFTL	NCAPD3	1366	P42695
QRRFSVSTLRNLGLG	CYP2D7	131	A0A087X1C5
FNLRSGRTRRALDIP	PRPF8	411	Q6P2Q9
PSLRSRNTIFTLGTR	VPS52	336	Q8N1B4
PLGQTVQSELFRSRL	TRAPPC1	116	Q9Y5R8
SRSLVLNRLRPVASG	ZC3H3	571	Q8IXZ2
GTTVLNLQPRARRFL	SLC9A2	701	Q9UBY0
LSLLSLAGRTQRPRT	SLC26A1	496	Q9H2B4
LAGRTQRPRTALLAR	SLC26A1	501	Q9H2B4
LPRIALFSTRTINAG	SUV39H2	351	Q9H5I1
RRNRVSFLGVATIEP	ERVK-8	6	P63133
RGRNNLTAPVSRTIF	PIEZO2	1081	Q9H5I5
ILFSNELHRRLSPRG	WWOX	301	Q9NZC7
GFSSLRLRPIRTLSS	RPS6KL1	131	Q9Y6S9
RRASSGLPRNTVVLF	STOML2	26	Q9UJZ1
RPLFIRNVLAAITRG	SLC7A6	476	Q92536
GSLSNLPRSFTLRRS	SH2D3C	21	Q8N5H7
RPFLSRESLSGQAVR	UQCRFS1P1	56	P0C7P4
LLGTRATFFLTRVQP	TGM7	71	Q96PF1
LRSLSLGPTFRERAL	RIPOR1	1121	Q6ZS17
GLRPSRLTRNGFTAL	TNNI3K	91	Q59H18
VSNGFRPRRSLLFIS	TFR2	461	Q9UP52
RLGFTPSVTIEQRRL	TRRAP	1991	Q9Y4A5
GLSLIRRFRSVFPLS	UNC13D	406	Q70J99
RPSLTGARRLVETIF	TERT	351	O14746
RATGTAFRRSPRNLI	TRPV5	146	Q9NQA5
SRGLRALVFLTTSPQ	TRIM56	631	Q9BRZ2
RLTAALSPFSGTRRI	TLX2	131	O43763
SRFLRFVTGRSRLPA	HECTD3	786	Q5T447
TFPAGSFQARLRLRV	NECTIN4	131	Q96NY8