Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
HumanPheno	Conjugated hyperbilirubinemia	UBR1 IARS1 INSR VPS33B SLC25A13	2.15e-05	38	47	5	HP:0002908
HumanPheno	Elevated gamma-glutamyltransferase level	UBR1 IARS1 INSR VPS33B SLC25A13	6.17e-05	47	47	5	HP:0030948
HumanPheno	Abnormal gamma-glutamyltransferase level	UBR1 IARS1 INSR VPS33B SLC25A13	6.84e-05	48	47	5	HP:0034444
HumanPheno	Intrahepatic cholestasis	UBR1 IARS1 SLC25A13 CYP7B1	6.98e-05	25	47	4	HP:0001406
HumanPheno	Abnormal liver physiology	UBR1 IARS1 SLC25A13 CYP7B1	8.20e-05	26	47	4	HP:0031865
Domain	Transmemb_17	TMEM216 TMEM80	8.66e-05	3	101	2	PF09799
Domain	Uncharacterised_TM-17	TMEM216 TMEM80	8.66e-05	3	101	2	IPR019184
Domain	DUF4704	NBEAL1 NBEA	2.86e-04	5	101	2	IPR031570
Domain	DUF4704	NBEAL1 NBEA	2.86e-04	5	101	2	PF15787
Domain	PH_BEACH	NBEAL1 NBEA	4.28e-04	6	101	2	PF14844
Domain	Anoct_dimer	ANO4 ANO3	5.97e-04	7	101	2	PF16178
Domain	Anoct_dimer	ANO4 ANO3	5.97e-04	7	101	2	IPR032394
Domain	PInositol-4-P-5-kinase	PIP5K1B PIP4K2C	5.97e-04	7	101	2	IPR023610
Domain	PH-BEACH_dom	NBEAL1 NBEA	7.94e-04	8	101	2	IPR023362
Domain	PIPKc	PIP5K1B PIP4K2C	7.94e-04	8	101	2	SM00330
Domain	-	PIP5K1B PIP4K2C	7.94e-04	8	101	2	3.30.800.10
Domain	-	NBEAL1 NBEA	7.94e-04	8	101	2	2.30.29.40
Domain	PIP5K	PIP5K1B PIP4K2C	7.94e-04	8	101	2	PF01504
Domain	PIPK	PIP5K1B PIP4K2C	7.94e-04	8	101	2	PS51455
Domain	PInositol-4-P-5-kinase_N	PIP5K1B PIP4K2C	7.94e-04	8	101	2	IPR027484
Domain	PInositol-4-P-5-kinase_C	PIP5K1B PIP4K2C	7.94e-04	8	101	2	IPR027483
Domain	PH_BEACH	NBEAL1 NBEA	7.94e-04	8	101	2	PS51783
Domain	-	PIP5K1B PIP4K2C	7.94e-04	8	101	2	3.30.810.10
Domain	PInositol-4-P-5-kinase_core	PIP5K1B PIP4K2C	7.94e-04	8	101	2	IPR002498
Domain	BEACH_dom	NBEAL1 NBEA	1.02e-03	9	101	2	IPR000409
Domain	BEACH	NBEAL1 NBEA	1.02e-03	9	101	2	PS50197
Domain	Beach	NBEAL1 NBEA	1.02e-03	9	101	2	PF02138
Domain	-	NBEAL1 NBEA	1.02e-03	9	101	2	1.10.1540.10
Domain	Beach	NBEAL1 NBEA	1.02e-03	9	101	2	SM01026
Domain	AAA+_ATPase	RNF213 ABCC9 DNAH12 ABCG2 DNAH9	1.11e-03	144	101	5	IPR003593
Domain	AAA	RNF213 ABCC9 DNAH12 ABCG2 DNAH9	1.11e-03	144	101	5	SM00382
Domain	Anoctamin	ANO4 ANO3	1.27e-03	10	101	2	PF04547
Domain	Anoctamin	ANO4 ANO3	1.27e-03	10	101	2	IPR007632
Domain	TRP_channel	TRPC4 TRPV2	1.54e-03	11	101	2	IPR004729
Domain	ARM-type_fold	DOCK3 NBEAL1 CKAP5 NBEA MEI1 THADA HEATR5B	2.44e-03	339	101	7	IPR016024
Domain	Dynein_heavy_chain_D4_dom	DNAH12 DNAH9	2.53e-03	14	101	2	IPR024317
Domain	Dynein_heavy_dom-2	DNAH12 DNAH9	2.53e-03	14	101	2	IPR013602
Domain	DHC_N2	DNAH12 DNAH9	2.53e-03	14	101	2	PF08393
Domain	AAA_8	DNAH12 DNAH9	2.53e-03	14	101	2	PF12780
Domain	ATPase_dyneun-rel_AAA	DNAH12 DNAH9	2.53e-03	14	101	2	IPR011704
Domain	AAA_5	DNAH12 DNAH9	2.53e-03	14	101	2	PF07728
Domain	DHC_fam	DNAH12 DNAH9	2.90e-03	15	101	2	IPR026983
Domain	Dynein_heavy_dom	DNAH12 DNAH9	2.90e-03	15	101	2	IPR004273
Domain	Dynein_heavy	DNAH12 DNAH9	2.90e-03	15	101	2	PF03028
Domain	GPCR_2_secretin-like	FZD8 ADGRG7 ADGRF4	4.20e-03	60	101	3	IPR000832
Domain	GPCR_2-like	FZD8 ADGRG7 ADGRF4	4.20e-03	60	101	3	IPR017981
Domain	G_PROTEIN_RECEP_F2_4	FZD8 ADGRG7 ADGRF4	4.40e-03	61	101	3	PS50261
Pubmed	E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins.	IPPK MYH9 IARS1 NELFB CKAP5 RNF213 SRP68 NBEA TMEM80 BIRC6 QRICH2 LONRF2 PIGM	4.02e-07	736	106	13	29676528
Pubmed	Defining the proximal interaction networks of Arf GTPases reveals a mechanism for the regulation of PLD1 and PI4KB.	MYH9 INSR NELFB RNF213 SRP68 NBEA BIRC6 CDKL5 THADA KIDINS220 NDC1 MRPS9 ANO3	7.38e-07	777	106	13	35844135
Pubmed	SARS-CoV-2 Nsp6 damages Drosophila heart and mouse cardiomyocytes through MGA/MAX complex-mediated increased glycolysis.	MYH9 COPA DPY19L1 IARS1 CKAP5 SRP68 BIRC6 FANCD2 GLMN THADA TMTC3 NUP93	8.17e-07	657	106	12	36180527
Pubmed	Organization and evolutionary relatedness of OR37 olfactory receptor genes in mouse and human.	OR2S2 OR13C6P OR13C7	5.93e-06	12	106	3	12906860
Pubmed	Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.	MYH9 COPA TRIO IARS1 CKAP5 SRP68 FANCD2 GLMN THADA KIDINS220 NDC1 VPS33B SLC25A13 MRPS9 NUP93 AQR	6.61e-06	1425	106	16	30948266
Pubmed	The ANO3/MUC15 locus is associated with eczema in families ascertained through asthma.	MUC15 ANO3	9.20e-06	2	106	2	22657408
Pubmed	Hypertonicity-responsive ubiquitin ligase RNF183 promotes Na, K-ATPase lysosomal degradation through ubiquitination of its β1 subunit.	MYH9 COPA CKAP5 SRP68 NBEA KIDINS220 NDC1 SLC25A13 RAB15	1.00e-05	449	106	9	31732153
Pubmed	TIF1γ inhibits lung adenocarcinoma EMT and metastasis by interacting with the TAF15/TBP complex.	MYH9 COPA IARS1 CKAP5 SRP68 SLC25A13	1.90e-05	179	106	6	36261009
Pubmed	Genomic screening identifies novel linkages and provides further evidence for a role of MYH9 in nonsyndromic cleft lip and palate.	MYH9 SDC2	2.76e-05	3	106	2	18716610
Pubmed	Basal vertebrates clarify the evolutionary history of ciliopathy-associated genes Tmem138 and Tmem216.	TMEM216 TMEM80	2.76e-05	3	106	2	22936720
Pubmed	The conserved transmembrane nucleoporin NDC1 is required for nuclear pore complex assembly in vertebrate cells.	NDC1 NUP93	2.76e-05	3	106	2	16600873
Pubmed	A novel PDZ protein regulates the activity of guanylyl cyclase C, the heat-stable enterotoxin receptor.	GUCY2C SLC34A1	2.76e-05	3	106	2	11950846
Pubmed	Apocrine glands are bystanders in hidradenitis suppurativa and their involvement is gender specific.	TUSC1 SEMA6D UPP1 DYRK3	3.26e-05	59	106	4	32031713
Pubmed	A new pathway for synthesis of phosphatidylinositol-4,5-bisphosphate.	PIP5K1B PIP4K2C	5.50e-05	4	106	2	9367159
Pubmed	FLJ10261 gene, located within the CCND1-EMS1 locus on human chromosome 11q13, encodes the eight-transmembrane protein homologous to C12orf3, C11orf25 and FLJ34272 gene products.	ANO4 ANO3	5.50e-05	4	106	2	12739008
Pubmed	A multi-factor trafficking site on the spliceosome remodeling enzyme BRR2 recruits C9ORF78 to regulate alternative splicing.	COPA NELFB CKAP5 GLMN NDC1 VPS33B SLC25A13 NUP93 AQR	5.61e-05	560	106	9	35241646
Pubmed	Defining the membrane proteome of NK cells.	MYH9 GPAA1 COPA DPY19L1 IARS1 CKAP5 RNF213 BIRC6 KIDINS220 NDC1 NUP93 HEATR5B AQR	5.71e-05	1168	106	13	19946888
Pubmed	Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.	COPA TRIO ITGA6 RNF213 NBEA BIRC6 FANCD2 GLMN NDC1 VPS33B NUP93 HERC1	8.68e-05	1049	106	12	27880917
Pubmed	Sur2 and Kcnj8 genes are tightly linked on the distal region of mouse chromosome 6.	ABCC9 GUCY2C	9.15e-05	5	106	2	9321483
Pubmed	The postsynaptic density 95/disc-large/zona occludens protein syntenin directly interacts with frizzled 7 and supports noncanonical Wnt signaling.	FZD8 SDC2	9.15e-05	5	106	2	18256285
Pubmed	Genetics of mirror movements identifies a multifunctional complex required for Netrin-1 guidance and lateralization of motor control.	ARHGEF7 ROBO3	9.15e-05	5	106	2	37172092
Pubmed	Trio cooperates with Myh9 to regulate neural crest-derived craniofacial development.	MYH9 TRIO	9.15e-05	5	106	2	33754063
Pubmed	KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.	KRT72 MYH9 COPA TRIO IARS1 CKAP5 SRP68 NBEA CDKL5 KIDINS220 CADPS MRPS9 HRG PIP4K2C	1.15e-04	1431	106	14	37142655
Pubmed	Targeting USP10 induces degradation of oncogenic ANLN in esophageal squamous cell carcinoma.	KRT72 MYH9 COPA IARS1 CKAP5 ITGA6 SRP68 SLC25A13 IMP4 MRPS9 RAB15 NUP93 AQR	1.19e-04	1257	106	13	36526897
Pubmed	Identification and characterization of TMEM16E and TMEM16F genes in silico.	ANO4 ANO3	1.37e-04	6	106	2	15067359
Pubmed	CHK2-BRCA1 tumor-suppressor axis restrains oncogenic Aurora-A kinase to ensure proper mitotic microtubule assembly.	UBR1 MYH9 COPA IARS1 CKAP5 SRP68 NDC1 NUP93	1.40e-04	494	106	8	26831064
Pubmed	LMBR1L regulates lymphopoiesis through Wnt/β-catenin signaling.	COPA IARS1 SRP68 FANCD2 GLMN THADA KIDINS220 NDC1 TMTC3 NUP93 HEATR5B	1.45e-04	942	106	11	31073040
Pubmed	Systematically defining selective autophagy receptor-specific cargo using autophagosome content profiling.	MYH9 GPAA1 COPA TRIO IARS1 SRP68 BIRC6 GLMN KIDINS220 NDC1 TMTC3 SDC2 AQR	1.62e-04	1297	106	13	33545068
Pubmed	Localization of mRNAs for phosphatidylinositol phosphate kinases in the mouse brain during development.	PIP5K1B PIP4K2C	1.91e-04	7	106	2	15018809
Pubmed	Personal receptor repertoires: olfaction as a model.	OR2S2 OR8K3 OR13C7	2.15e-04	38	106	3	22908908
Pubmed	BioID reveals an ATG9A interaction with ATG13-ATG101 in the degradation of p62/SQSTM1-ubiquitin clusters.	NBEAL1 NBEA KIDINS220 VPS33B TBC1D23 HEATR5B	2.47e-04	285	106	6	34369648
Pubmed	Btk-dependent regulation of phosphoinositide synthesis.	PIP5K1B PIP4K2C	2.55e-04	8	106	2	15046600
Pubmed	Blood-Brain Barrier: From Physiology to Disease and Back.	INSR ABCC9 SLC16A2 ABCG2	3.08e-04	105	106	4	30280653
Pubmed	A Multipronged Unbiased Strategy Guides the Development of an Anti-EGFR/EPHA2-Bispecific Antibody for Combination Cancer Therapy.	TRIO INSR ITGA6 KIDINS220 NDC1 SEMA6D VPS33B	3.16e-04	421	106	7	36976175
Pubmed	Comparative phenotypic analysis of the two major splice isoforms of phosphatidylinositol phosphate kinase type Iγ in vivo.	ITGA6 PIP5K1B	3.27e-04	9	106	2	22976293
Pubmed	Small subfamily of olfactory receptor genes: structural features, expression pattern and genomic organization.	OR2S2 OR13C7	3.27e-04	9	106	2	10452948
Pubmed	Assembly of the U5 snRNP component PRPF8 is controlled by the HSP90/R2TP chaperones.	MYH9 COPA IARS1 NELFB CKAP5 SRP68 BIRC6 ARHGEF7 SLC25A13 MRPS9 UPP1 PIP4K2C AQR	3.76e-04	1415	106	13	28515276
Pubmed	LRRC31 inhibits DNA repair and sensitizes breast cancer brain metastasis to radiation therapy.	MYH9 COPA TRIO CKAP5 TMTC3	3.96e-04	202	106	5	33005030
Pubmed	Multilevel proteomics reveals host perturbations by SARS-CoV-2 and SARS-CoV.	GPAA1 SGCD ITGA6 RNF213 FBXO46 FANCD2 THADA NDC1 ZDHHC9 NUP93 HERC1	4.01e-04	1061	106	11	33845483
Pubmed	Multiple mouse chromosomal loci for dynein-based motility.	DNAH12 DNAH9 SDC2	4.05e-04	47	106	3	8812413
Pubmed	Impaired Spermatogenesis, Muscle, and Erythrocyte Function in U12 Intron Splicing-Defective Zrsr1 Mutant Mice.	GPAA1 MEI1 TMEM80	4.05e-04	47	106	3	29617656
Pubmed	Anoctamin/TMEM16 family members are Ca2+-activated Cl- channels.	ANO4 ANO3	4.08e-04	10	106	2	19015192
Pubmed	Keratin 5-Cre-driven excision of nonmuscle myosin IIA in early embryo trophectoderm leads to placenta defects and embryonic lethality.	MYH9 ITGA6	4.08e-04	10	106	2	23911870
Pubmed	Calcium-dependent phospholipid scramblase activity of TMEM16 protein family members.	ANO4 ANO3	4.08e-04	10	106	2	23532839
Pubmed	Structure and function of TMEM16 proteins (anoctamins).	ANO4 ANO3	4.08e-04	10	106	2	24692353
Pubmed	Direct interaction between hnRNP-M and CDC5L/PLRG1 proteins affects alternative splice site choice.	MYH9 COPA CKAP5 SRP68 FANCD2 VPS33B NUP93 AQR	4.21e-04	582	106	8	20467437
Pubmed	The E3 ubiquitin ligase and RNA-binding protein ZNF598 orchestrates ribosome quality control of premature polyadenylated mRNAs.	MYH9 COPA IARS1 CKAP5 SLC25A13 NUP93	4.57e-04	320	106	6	28685749
Pubmed	Inherited genetic markers discovered to date are able to identify a significant number of men at considerably elevated risk for prostate cancer.	ITGA6 THADA	4.97e-04	11	106	2	20878950
Pubmed	Immunolocalization of extracellular matrix components and integrins during mouse liver development.	ITGA6 SDC2	4.97e-04	11	106	2	15368439
Pubmed	FBW7 suppresses ovarian cancer development by targeting the N6-methyladenosine binding protein YTHDF2.	MYH9 COPA IARS1 RNF213 ARHGEF7 SLC25A13 MRPS9 NUP93	5.19e-04	601	106	8	33658012
Pubmed	Establishment and Dysfunction of the Blood-Brain Barrier.	INSR SLC16A2 ABCG2	5.46e-04	52	106	3	26590417
Pubmed	Interactions of the Antiviral Factor Interferon Gamma-Inducible Protein 16 (IFI16) Mediate Immune Signaling and Herpes Simplex Virus-1 Immunosuppression.	CKAP5 RNF213 SRP68 NDC1 IMP4 NUP93	5.54e-04	332	106	6	25693804
Pubmed	Macrophages monitor tissue osmolarity and induce inflammatory response through NLRP3 and NLRC4 inflammasome activation.	TRPV2 PIP5K1B	5.95e-04	12	106	2	25959047
Pubmed	Synergistic activities of alpha3 and alpha6 integrins are required during apical ectodermal ridge formation and organogenesis in the mouse.	ITGA6 SDC2	5.95e-04	12	106	2	10433923
Pubmed	Interaction of LATS1 with SMAC links the MST2/Hippo pathway with apoptosis in an IAP-dependent manner.	IPPK CKAP5 BIRC6 DNAH12 SLC25A13	6.08e-04	222	106	5	35941108
Pubmed	A conserved acetylation switch enables pharmacological control of tubby-like protein stability.	BIRC6 TTC21B MRPS9 PIP4K2C MAST3	6.21e-04	223	106	5	33187986
Pubmed	Hdac4 Interactions in Huntington's Disease Viewed Through the Prism of Multiomics.	COPA TRIO SH3BP1 CCM2 CADPS ARHGEF7 MAST3	6.47e-04	475	106	7	31040226
Pubmed	RUFY1 binds Arl8b and mediates endosome-to-TGN CI-M6PR retrieval for cargo sorting to lysosomes.	MYH9 COPA IARS1 RNF213 SLC25A13 NUP93	6.67e-04	344	106	6	36282215
Pubmed	ER-export and ARFRP1/AP-1-dependent delivery of SARS-CoV-2 Envelope to lysosomes controls late stages of viral replication.	COPA DPY19L1 ITGA6 BIRC6 KIDINS220 NDC1 TMTC3 SLC25A13 TBC1D23 SDC2	6.72e-04	952	106	10	38569033
Pubmed	A Map of Human Mitochondrial Protein Interactions Linked to Neurodegeneration Reveals New Mechanisms of Redox Homeostasis and NF-κB Signaling.	COPA DPY19L1 IARS1 SRP68 KIDINS220 SLC25A13 MRPS9 NUP93 PIP4K2C	6.86e-04	786	106	9	29128334
Pubmed	Genome-wide association study identifies eight new risk loci for polycystic ovary syndrome.	INSR THADA	7.02e-04	13	106	2	22885925
Pubmed	Neuron-specific protein network mapping of autism risk genes identifies shared biological mechanisms and disease-relevant pathologies.	DOCK3 MYH9 TRIO IARS1 CKAP5 NBEA BIRC6 CDKL5 CADPS ARHGEF7 MRPS9	7.22e-04	1139	106	11	36417873
Pubmed	METTL3 protects METTL14 from STUB1-mediated degradation to maintain m6 A homeostasis.	UBR1 COPA CKAP5 SRP68 HERC1	7.28e-04	231	106	5	36597993
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	DOCK3 NELFB RNF213 BIRC6 THADA TTC21B MAST3	8.04e-04	493	106	7	15368895
Pubmed	MKRN2 Physically Interacts with GLE1 to Regulate mRNA Export and Zebrafish Retinal Development.	MYH9 TRIO IARS1 CKAP5 ITGA6 SEMA6D	8.20e-04	358	106	6	32460013
Pubmed	Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.	UBR1 MYH9 COPA IARS1 CKAP5 SRP68 BIRC6 VPS33B SLC25A13 NUP93 PIP4K2C AQR	8.67e-04	1353	106	12	29467282
Pubmed	Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.	MYH9 COPA CKAP5 SRP68 BIRC6 SLC25A13 NUP93 AQR	8.90e-04	653	106	8	22586326
Pubmed	Characterization of the piRNA complex from rat testes.	GLMN NDC1 RAD54B MRPS9	9.09e-04	140	106	4	16778019
Pubmed	Common body mass index-associated variants confer risk of extreme obesity.	MUC15 ANO3	9.41e-04	15	106	2	19553259
Pubmed	New interaction partners for Nek4.1 and Nek4.2 isoforms: from the DNA damage response to RNA splicing.	MYH9 TRIO SIDT1 CADPS SLC25A13 TTC21B DYRK3	1.01e-03	513	106	7	25798074
Pubmed	The RNA-methyltransferase Misu (NSun2) poises epidermal stem cells to differentiate.	KRT72 ITGA6	1.07e-03	16	106	2	22144916
Pubmed	HIV latency. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells.	HORMAD2 CKAP5	1.07e-03	16	106	2	24968937
Pubmed	Genetic mosaic analysis reveals a major role for frizzled 4 and frizzled 8 in controlling ureteric growth in the developing kidney.	FZD8 SLC34A1	1.07e-03	16	106	2	21343368
Pubmed	Tissue distribution, ontogeny, and hormonal regulation of xenobiotic transporters in mouse kidneys.	SLC34A1 ABCG2	1.07e-03	16	106	2	19679677
Pubmed	SNX27-driven membrane localisation of OTULIN antagonises linear ubiquitination and NF-κB signalling activation.	CKAP5 CDKL5 KIDINS220 ARHGEF7 PIP4K2C HEATR5B	1.08e-03	378	106	6	34315543
Pubmed	The STUbL RNF4 regulates protein group SUMOylation by targeting the SUMO conjugation machinery.	GPAA1 DPY19L1 IARS1 NELFB CKAP5 ITGA6 NDC1 TMTC3 NUP93 TBC1D23 AQR	1.12e-03	1203	106	11	29180619
Pubmed	Genome-wide association analyses identify 18 new loci associated with serum urate concentrations.	INSR QRICH2 ABCG2	1.14e-03	67	106	3	23263486
Pubmed	Multi-omics profiling identifies a deregulated FUS-MAP1B axis in ALS/FTD-associated UBQLN2 mutants.	MYH9 COPA IARS1 SLC25A13 NUP93	1.15e-03	256	106	5	35777956
Pubmed	Deubiquitinating enzyme PSMD14 promotes tumor metastasis through stabilizing SNAIL in human esophageal squamous cell carcinoma.	MYH9 COPA IARS1 SLC25A13 PIP5K1B NUP93	1.16e-03	383	106	6	29331416
Pubmed	Dissecting and manipulating the pathway for glycosylphos-phatidylinositol-anchor biosynthesis.	SEMA6D PIGM	1.21e-03	17	106	2	11102867
Pubmed	Functional screen identifies regulators of murine hematopoietic stem cell repopulation.	NBEA P2RY14	1.36e-03	18	106	2	26880577
Pubmed	Putative Protein Interactome of the Rhomboid Protease RHBDL4.	COPA NDC1	1.36e-03	18	106	2	36857408
Pubmed	Mutation analysis of 18 nephronophthisis associated ciliopathy disease genes using a DNA pooling and next generation sequencing strategy.	TMEM216 TTC21B	1.36e-03	18	106	2	21068128
Pubmed	ISG15 Connects Autophagy and IFN-γ-Dependent Control of Toxoplasma gondii Infection in Human Cells.	MYH9 COPA DPY19L1 IARS1 RNF213	1.41e-03	268	106	5	33024031
Pubmed	Cytoplasmic dynein-1 cargo diversity is mediated by the combinatorial assembly of FTS-Hook-FHIP complexes.	MYH9 NBEA TBC1D23	1.41e-03	72	106	3	34882091
Pubmed	Exome sequencing reveals pathogenic mutations in 91 strains of mice with Mendelian disorders.	NDC1 KCNN2 ROBO3	1.41e-03	72	106	3	25917818
Pubmed	Promoting anti-tumor immunity by targeting TMUB1 to modulate PD-L1 polyubiquitination and glycosylation.	COPA CKAP5 NUP93	1.41e-03	72	106	3	36376293
Pubmed	Insights into the ubiquitin-proteasome system of human embryonic stem cells.	COPA BIRC6 KIDINS220 NUP93 AQR	1.43e-03	269	106	5	29511261
Pubmed	KAP1 facilitates reinstatement of heterochromatin after DNA replication.	COPA NELFB BIRC6 FANCD2 VPS33B SLC25A13 MRPS9 TBC1D23	1.43e-03	704	106	8	29955894
Pubmed	SERBP1 Promotes Stress Granule Clearance by Regulating 26S Proteasome Activity and G3BP1 Ubiquitination and Protects Male Germ Cells from Thermostimuli Damage.	MYH9 IARS1 SRP68 FANCD2 NDC1 SLC16A2 SLC25A13 NUP93 HEATR5B	1.48e-03	878	106	9	37223481
Pubmed	Repression of rRNA transcription by PARIS contributes to Parkinson's disease.	COPA IARS1 SRP68 SLC25A13 MRPS9	1.50e-03	272	106	5	25315684
Pubmed	Genome-wide association study evaluating lipoprotein-associated phospholipase A2 mass and activity at baseline and after rosuvastatin therapy.	RNF213 ABCG2	1.52e-03	19	106	2	23118302
Pubmed	A novel custom resequencing array for dilated cardiomyopathy.	SGCD ABCC9	1.52e-03	19	106	2	20474083
Pubmed	Identification of seven new prostate cancer susceptibility loci through a genome-wide association study.	ITGA6 THADA	1.52e-03	19	106	2	19767753
Pubmed	Odorant and vomeronasal receptor genes in two mouse genome assemblies.	OR5AU1 OR8K3 OR13C7	1.52e-03	74	106	3	15081110
Pubmed	Shotgun sequencing of the human transcriptome with ORF expressed sequence tags.	NBEAL1 SIDT1 RNF213 GUCY2C EPC1 RAD54B MAST3	1.54e-03	552	106	7	10737800
Pubmed	Fine mapping of collagen-induced arthritis quantitative trait loci in an advanced intercross line.	UBR1 SEMA6D	1.69e-03	20	106	2	17082620
Pubmed	Prostate cancer risk-associated variants reported from genome-wide association studies: meta-analysis and their contribution to genetic Variation.	ITGA6 THADA	1.69e-03	20	106	2	20564319
Pubmed	Proteomic analysis reveals novel ligands and substrates for LNX1 E3 ubiquitin ligase.	MYH9 COPA IARS1	1.84e-03	79	106	3	29121065
Pubmed	Regulation of the endosomal SNX27-retromer by OTULIN.	KIDINS220 ARHGEF7	1.86e-03	21	106	2	31541095
Interaction	ARL10 interactions	IPPK NELFB SRP68 BIRC6 FANCD2 THADA C5AR1 HCRTR2	4.60e-06	189	100	8	int:ARL10
Interaction	APLNR interactions	DPY19L1 ABHD18 FANCD2 GLMN THADA KIDINS220 NDC1 ZDHHC9	1.03e-05	211	100	8	int:APLNR
Cytoband	3q12.2	ADGRG7 TBC1D23	1.92e-04	9	107	2	3q12.2
GeneFamily	WD repeat domain containing\|BEACH domain containing	NBEAL1 NBEA	5.84e-04	9	74	2	1230
GeneFamily	Anoctamins	ANO4 ANO3	7.28e-04	10	74	2	865
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Mesenchymal-glomerular_mesenchymal_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	ANO4 TRPC4 FANCD2 SLC34A1 PIP5K1B ANO3 MAST3	1.53e-07	167	106	7	b4ef07117d14da3d5fbced949e4dfcb01c392295
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell-mesangial_typical\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	ANO4 TRPC4 FANCD2 SLC34A1 PIP5K1B ANO3 MAST3	1.53e-07	167	106	7	94fc7df7ca55cd722a8dbd153201a29891217473
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	ANO4 TRPC4 FANCD2 SLC34A1 PIP5K1B ANO3 MAST3	1.53e-07	167	106	7	eff3723fe60755272eca237459165e436e919ece
ToppCell	droplet-Bladder-Unstain-18m-Endothelial-nan\|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ABCC9 SEMA6D TRPV2 PIP5K1B CYP7B1 UPP1 ABCG2	3.18e-07	186	106	7	e3a14f3ccadbf3211822c67b8956ee01f563307a
ToppCell	LPS_IL1RA_TNF-Mesenchymal_myocytic-Pericyte-Pericyte_2\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	TRPC4 ABCC9 NBEA SEMA6D TRPV2 P2RY14 SDC2	5.19e-07	200	106	7	d2fcd3bd7c3223875f027eeb48ff621192a5f242
ToppCell	LPS_IL1RA-Mesenchymal_myocytic-Pericyte-Pericyte_2\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	NBEAL1 TRPC4 ABCC9 SEMA6D TRPV2 P2RY14 SDC2	5.19e-07	200	106	7	cf883ba5dbe6350b93142d625a52b25ff2a8bb63
ToppCell	E16.5-samps-Mesenchymal-Myofibroblast-Migrating_MyoFibroblast\|E16.5-samps / Age Group, Lineage, Cell class and subclass	ANKMY1 SEMA6D ZDHHC9 KCNN2 P2RY14 ROBO3	1.95e-06	155	106	6	1882fa5fd25f77d6e3ac47b613f6fb3c67d8e50c
ToppCell	droplet-Fat-Scat-18m-Mesenchymal-nan\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ANO4 CYP2F1 MC2R ABCC9 LRRC4 GUCY2C	2.61e-06	163	106	6	1eec7f5e5fed05fa21d3f81db588f10605f08ea7
ToppCell	CV-Mild-7\|Mild / Virus stimulation, Condition and Cluster	IPPK DPY19L1 IARS1 FANCD2 CDKL5 GLMN	3.68e-06	173	106	6	c9bbca9313a0fdf146c8c995624b94b937e818d8
ToppCell	tumor_Lung-Fibroblasts-Pericytes\|Fibroblasts / Location, Cell class and cell subclass	MYH9 SEMA6D TRPV2 PIP5K1B P2RY14 SDC2	6.11e-06	189	106	6	9c407b17d7945e81e1ae6c18452f5d20fb09d563
ToppCell	LPS-IL1RA-Stromal_mesenchymal-Lung_smooth_muscle\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ANO4 DOCK3 SGCD ABCC9 P2RY14 SDC2	6.49e-06	191	106	6	7853ac7dff649150e6ff27cd4c8cf7c1fc034ed4
ToppCell	saliva-Severe-critical_progression_d12-22_no-steroids-Epithelial-Epithelial,_Airway-secretory_cell-Epi-Secretory\|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)	CYP2F1 MUC15 NBEA TUSC1 SEMA6D ADGRF4	6.69e-06	192	106	6	8899d81306770adda893b5e146df1253971754c5
ToppCell	saliva-Severe-critical_progression_d12-22_no-steroids-Epithelial-Epithelial,_Airway-secretory_cell\|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)	CYP2F1 MUC15 NBEA TUSC1 SEMA6D ADGRF4	6.69e-06	192	106	6	5fda9a465c9f77c7fa1a3ea07a2b0374bbc23b2a
ToppCell	Posterior_cortex-Neuronal\|Posterior_cortex / BrainAtlas - Mouse McCarroll V32	DOCK3 SH3BP1 NBEA CADPS HERC1 LONRF2	6.89e-06	193	106	6	b4989e3436e84dbec3789b46057e0f7a0ebf09d4
ToppCell	LPS_IL1RA-Mesenchymal_myocytic-Myofibroblastic-Myofibroblast\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	ANO4 DOCK3 SGCD NUP93 LONRF2 SDC2	8.44e-06	200	106	6	8988f113708eef7d9d2a6a6c1bcfd7c8f9804d3e
ToppCell	LPS_anti-TNF-Mesenchymal_myocytic-Pericyte-Pericyte_2\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	MYH9 ABCC9 SEMA6D TRPV2 P2RY14 SDC2	8.44e-06	200	106	6	786f1ae53e60b5ffbf4bfd393d10b802478148b3
ToppCell	LPS_only-Mesenchymal_myocytic-Pericyte-Pericyte_2\|LPS_only / Treatment groups by lineage, cell group, cell type	NBEAL1 ABCC9 NBEA SEMA6D P2RY14 SDC2	8.44e-06	200	106	6	69edc375d85689300d1dbc1217fedc40063ecdcb
ToppCell	390C-Myeloid-Macrophage-SPP1+_Macrophage_4\|Macrophage / Donor, Lineage, Cell class and subclass (all cells)	SIDT1 TPBGL ZDHHC9 EPC1 SDC2	1.73e-05	134	106	5	9e12aac8f42790c2f104dfd61c87aa99fc7925f1
ToppCell	CV-Mild-7\|CV / Virus stimulation, Condition and Cluster	IPPK IARS1 FANCD2 CDKL5 GLMN	5.41e-05	170	106	5	25ebde7d2f8ae1afdfaf5876284ff20bb179eb10
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_3\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	MYH9 SGCD KCNN2 ANO3 MAST3	6.04e-05	174	106	5	9cc7251661ea2b1565eef1dfb8cf6dec3ade13d4
ToppCell	3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.2.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CYP2F1 MUC15 NBEA DNAH12 DNAH9	6.37e-05	176	106	5	dee780cfa85234a7cd7bf440b66b84cec959893e
ToppCell	5'-Adult-SmallIntestine-Mesenchymal-fibroblastic-Stromal_3_(C7+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SGCD ABCC9 NBEA FZD8 LONRF2	6.55e-05	177	106	5	bd602db857f37869ef76d14c05ef522c509f08ee
ToppCell	Control-Neu_4\|World / 5 Neutrophil clusters in COVID-19 patients	DPY19L1 NBEAL1 CKAP5 FANCD2 AQR	7.86e-05	184	106	5	ce7f044956613118ee2e9fb6af2455c3166cb414
ToppCell	COVID-19-Heart-Pericyte\|Heart / Disease (COVID-19 only), tissue and cell type	NBEAL1 TRPC4 ABCC9 ARHGEF7 P2RY14	7.86e-05	184	106	5	21790cdfa3b4036ad413fd44b94e31563116f25f
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	TRPC4 ABCC9 CADPS PIP5K1B ANO3	8.06e-05	185	106	5	51dfe6ac7df8b330343b37e3bee71e5c65267189
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte-\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	TRPC4 ABCC9 CADPS PIP5K1B ANO3	8.06e-05	185	106	5	a8c02cec3c414f3a0da9f2d6d28ce563b0030705
ToppCell	3'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-pericyte_cell-Pericytes-Pericytes_L.2.3.3.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	TRPC4 ABCC9 SEMA6D ARHGEF7 P2RY14	8.27e-05	186	106	5	888e85a025bd982d36c910db0f5a3385b1ca3b28
ToppCell	Fetal_29-31_weeks-Mesenchymal-pericyte_cell-D150\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	ABCC9 NBEA SEMA6D P2RY14 SDC2	8.48e-05	187	106	5	fa01a61bfd13feb033ba1e35cf513707b1bff8c8
ToppCell	COPD-Stromal-Pericyte\|Stromal / Disease state, Lineage and Cell class	MYH9 TRPC4 SEMA6D ARHGEF7 UPP1	8.48e-05	187	106	5	406ecd1dabb3ed8d871aef159f7bd1e383434953
ToppCell	Fetal_29-31_weeks-Mesenchymal-pericyte_cell\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	TRPC4 ABCC9 SEMA6D P2RY14 SDC2	8.48e-05	187	106	5	a2bf958ea59c359a265bfa437d59315e1920cdd4
ToppCell	LPS-IL1RA-Stromal_mesenchymal-Lung_smooth_muscle-Myofibroblast\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ANO4 DOCK3 SGCD LONRF2 SDC2	8.70e-05	188	106	5	3177b2c1723268d330d3e9f24f9e24492ace6286
ToppCell	LPS-antiTNF-Stromal_mesenchymal-Lung_smooth_muscle\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ANO4 DOCK3 SGCD ABCC9 SDC2	8.92e-05	189	106	5	7ab1cfc1657277858339f7258a0c4ae9cb42fdf8
ToppCell	CD8+_Memory_T_cell-CV-7\|CD8+_Memory_T_cell / cell class, Virus stimulation and cluster	UBR1 RNF213 BIRC6 KIDINS220 NDC1	9.37e-05	191	106	5	9454f642c3621370fa23640b631301346b300950
ToppCell	LPS_only-Stromal_mesenchymal-Lung_smooth_muscle\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ANO4 DOCK3 SGCD ABCC9 SDC2	9.37e-05	191	106	5	08042952431ca1a6fd7dfc13f36eb28643979598
ToppCell	3'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-pericyte_cell\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	TRPC4 ABCC9 SEMA6D P2RY14 SDC2	9.37e-05	191	106	5	1626b23a57429f835fddc052e3c57f63a4e5b8bb
ToppCell	control-Myeloid-Mast_cell\|Myeloid / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	NBEA MEI1 CADPS TRPV2 SLC41A1	9.37e-05	191	106	5	afebdc59a1f884ce3f2f5fe040e16b0e95e4e7c5
ToppCell	3'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-pericyte_cell-Pericytes\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	TRPC4 ABCC9 SEMA6D P2RY14 SDC2	9.37e-05	191	106	5	716dfa7fccbd62b5f574792e68a26dc6c45511dc
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	TRPC4 ABCC9 CADPS PIP5K1B ANO3	9.60e-05	192	106	5	24e2f15f5767a97eb3b389922bcfd7b13805e1ce
ToppCell	LPS-IL1RA+antiTNF-Stromal_mesenchymal-Lung_smooth_muscle\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ANO4 DOCK3 SGCD ABCC9 SDC2	9.60e-05	192	106	5	992d08092edbc68c47b945deb8708379738c239a
ToppCell	Fetal_29-31_weeks-Mesenchymal-myofibroblast_cell-D150\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	ANO4 DOCK3 SEMA6D CADPS ANO3	9.60e-05	192	106	5	72881b280a415e65f87a80ca1369cbb0b722a0c4
ToppCell	IPF-Stromal-Pericyte\|Stromal / Disease state, Lineage and Cell class	MYH9 TRPC4 SEMA6D ARHGEF7 P2RY14	1.01e-04	194	106	5	3892b188f424ffb80f3c75a1b6709a21c1e1601d
ToppCell	PCW_10-12-Mesenchymal-Mesenchymal_myocytic\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	ANO4 MYH9 ABCC9 SEMA6D SDC2	1.01e-04	194	106	5	67f5e2f05a8de2213ab80d5ea16fdee121684633
ToppCell	3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	MUC15 NBEA LRRC4 DNAH12 DNAH9	1.03e-04	195	106	5	9651ee03738226ee10e901f8b9ec6a417eb9c301
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Vascular-Mural_cell-Pericyte-G\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	MYH9 TRPC4 ABCC9 P2RY14 SDC2	1.03e-04	195	106	5	d760d1423f9a8a373fe7b250ea9b1d67a0c0059f
ToppCell	Control-Neu_4\|Control / 5 Neutrophil clusters in COVID-19 patients	GPAA1 DPY19L1 CKAP5 FANCD2 AQR	1.06e-04	196	106	5	b8b7b54ca17a08fa775507bb22b1c7248ada8f40
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Vascular-Mural_cell-Scavenging_pericyte\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	MYH9 TRPC4 ABCC9 P2RY14 SDC2	1.06e-04	196	106	5	cb61757646653f89faba503cb5d99e5dd5197b4c
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Vascular-Mural_cell-Scavenging_pericyte-G\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	MYH9 TRPC4 ABCC9 P2RY14 SDC2	1.06e-04	196	106	5	44e2df1b61e3819eae7e482bef0a733afe852d67
ToppCell	wk_15-18-Mesenchymal-Myofibro_&_SMC-Pericyte\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	ABCC9 SEMA6D TRPV2 P2RY14 SDC2	1.11e-04	198	106	5	76d46950c11cb4708866db0da54ce00d5c0adab8
ToppCell	Frontal_cortex-Neuronal\|Frontal_cortex / BrainAtlas - Mouse McCarroll V32	DOCK3 NBEA CDKL5 CADPS LONRF2	1.14e-04	199	106	5	f88039d862f3bfa01dc39d2de4f3f548dc5a0e61
ToppCell	distal-3-mesenchymal-Pericyte\|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	TRPC4 ABCC9 SEMA6D P2RY14 SDC2	1.16e-04	200	106	5	911db29f254bb697610e720ba78816e2c7f57933
ToppCell	Control_saline-Mesenchymal_myocytic-Myofibroblastic-Myofibroblast\|Control_saline / Treatment groups by lineage, cell group, cell type	ANO4 DOCK3 SGCD LONRF2 SDC2	1.16e-04	200	106	5	c5e051f1aac8dda376c342a9932785a23450e073
ToppCell	LPS_IL1RA_TNF-Mesenchymal_myocytic-Pericyte\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	ABCC9 SEMA6D TRPV2 P2RY14 SDC2	1.16e-04	200	106	5	b5b5a32925f225610fe25a021a742d6397162863
ToppCell	Control_saline-Mesenchymal_myocytic-Myofibroblastic\|Control_saline / Treatment groups by lineage, cell group, cell type	ANO4 DOCK3 SGCD LONRF2 SDC2	1.16e-04	200	106	5	9d5b3c2dcfa55d50acc2ce2c319d51aa525d4cd1
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW19-Neuroepithelial-Proteoglycan-expressing_cell\|GW19 / Sample Type, Dataset, Time_group, and Cell type.	MEI1 FSIP2 PIP5K1B ABCG2 C5AR1	1.16e-04	200	106	5	aafe594c88710f8c53d59667cdac5035e08f5511
ToppCell	distal-mesenchymal-Pericyte\|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	TRPC4 ABCC9 SEMA6D P2RY14 SDC2	1.16e-04	200	106	5	fe31287cfb51d45643bdedbaa5efc03ed87263c6
ToppCell	LPS_only-Mesenchymal_myocytic-Pericyte\|LPS_only / Treatment groups by lineage, cell group, cell type	NBEAL1 ABCC9 SEMA6D P2RY14 SDC2	1.16e-04	200	106	5	8c8ef2b19ab5b1bfc0fae6c38a330f464f28e86f
ToppCell	distal-mesenchymal-Pericyte-2\|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	TRPC4 ABCC9 SEMA6D P2RY14 SDC2	1.16e-04	200	106	5	867935701fac71a3fe01578362da0676f959736c
ToppCell	LPS_IL1RA_TNF-Mesenchymal_myocytic-Myofibroblastic-Myofibroblast\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	ANO4 DOCK3 NUP93 LONRF2 SDC2	1.16e-04	200	106	5	dcdaec3ca3a3024dc1b8788c417003f84c2bffdc
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW19-Neuroepithelial\|GW19 / Sample Type, Dataset, Time_group, and Cell type.	MEI1 FSIP2 PIP5K1B ABCG2 C5AR1	1.16e-04	200	106	5	a6f0f5f644b7262878b0b9d4d90ee407c4124dd9
ToppCell	distal-2-mesenchymal-Pericyte\|2 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	TRPC4 ABCC9 SEMA6D P2RY14 SDC2	1.16e-04	200	106	5	4ee0b2f56c2652435fa78bf6b3c90cea28df74e0
Disease	uric acid measurement	IPPK INSR BIRC6 QRICH2 GLMN CCM2 NDC1 PIP5K1B ABCG2 SLC41A1 HCRTR2	7.97e-06	610	101	11	EFO_0004761
Disease	Drug habituation	ANO4 PIWIL1 INSR SEMA6D TTC21B	4.84e-05	115	101	5	C0013170
Disease	Drug abuse	ANO4 PIWIL1 INSR SEMA6D TTC21B	4.84e-05	115	101	5	C0013146
Disease	Prescription Drug Abuse	ANO4 PIWIL1 INSR SEMA6D TTC21B	4.84e-05	115	101	5	C4316881
Disease	Substance-Related Disorders	ANO4 PIWIL1 INSR SEMA6D TTC21B	4.84e-05	115	101	5	C0236969
Disease	Drug Use Disorders	ANO4 PIWIL1 INSR SEMA6D TTC21B	4.84e-05	115	101	5	C0013222
Disease	Drug Dependence	ANO4 PIWIL1 INSR SEMA6D TTC21B	4.84e-05	115	101	5	C1510472
Disease	Substance Dependence	ANO4 PIWIL1 INSR SEMA6D TTC21B	4.84e-05	115	101	5	C0038580
Disease	Substance Use Disorders	ANO4 PIWIL1 INSR SEMA6D TTC21B	4.84e-05	115	101	5	C0038586
Disease	Organic Mental Disorders, Substance-Induced	ANO4 PIWIL1 INSR SEMA6D TTC21B	4.84e-05	115	101	5	C0029231
Disease	Substance abuse problem	ANO4 PIWIL1 INSR SEMA6D TTC21B	5.05e-05	116	101	5	C0740858
Disease	age at diagnosis, substance-related disorder	BIRC6 SEMA6D	1.72e-04	6	101	2	EFO_0004918, MONDO_0002494
Disease	waist-hip ratio	IPPK SGCD INSR BIRC6 THADA CCM2 KIDINS220 CADPS EPC1 RAB15 TBC1D23 LONRF2 ANO3	2.83e-04	1226	101	13	EFO_0004343
Disease	Cleft palate, cleft lip	MYH9 SGCD ABCC9 THADA SYT14 RAD54B	4.05e-04	279	101	6	EFO_0003959, HP_0000175
Disease	cerebral cavernous malformation (implicated_via_orthology)	RNF213 CCM2	6.25e-04	11	101	2	DOID:0060669 (implicated_via_orthology)
Disease	receptor-interacting serine/threonine-protein kinase 2 measurement	IPPK HRG	6.25e-04	11	101	2	EFO_0802997
Disease	Metastatic melanoma	TRIO CDKL5 GUCY2C	8.51e-04	54	101	3	C0278883
Disease	Nephronophthisis	TTC21B SLC41A1	8.83e-04	13	101	2	C0687120
Disease	urolithiasis	SLC34A1 ABCG2 HCRTR2	1.33e-03	63	101	3	MONDO_0024647
Disease	Febrile seizure (within the age range of 3 months to 6 years)	HERC1 ANO3	1.71e-03	18	101	2	HP_0002373
Disease	Cleft palate	SGCD IARS1 SYT14	1.88e-03	71	101	3	HP_0000175
Disease	uridine diphosphate measurement	CDKL5 KCNN2	2.12e-03	20	101	2	EFO_0010545
Disease	Familial aplasia of the vermis	TMEM216 TTC21B	2.12e-03	20	101	2	cv:C0431399
Disease	risky sexual behaviour measurement	BIRC6 SEMA6D CYP7B1 MAST3	2.75e-03	169	101	4	EFO_0007877
Disease	hippocampal sclerosis of aging	ABCC9 KCNN2	2.80e-03	23	101	2	EFO_0005678
Disease	metabolite measurement	GPAA1 PIWIL1 INSR MC2R SLC44A5 SLC34A1 ABCG2	3.17e-03	560	101	7	EFO_0004725

Protein segments in the cluster

Peptide	Gene	Start	Entry
TDNKIMLELARLYLA	TTC21B	916	Q7Z4L5
LLHLTLEIMEKRYNL	EPC1	261	Q9H2F5
MTLAQLLTLLYDRKL	BIRC6	3981	Q9NR09
MGVSKLDILYRRLLL	ABHD18	1	Q0P651
MIVIFLTIAYLKLLF	ABCG2	636	Q9UNQ0
LSNLRYLMKFLARLA	SH3BP1	396	Q9Y3L3
MLFKALLIIYGILVI	ADGRF4	491	Q8IZF3
YLEKALLDMRALLQS	CRAT	606	P43155
ALLAMIYNKILRLST	ABCC9	386	O60706
KNERYLLLFPNVLLM	ARHGEF7	496	Q14155
IRKIMLLEFSQYLEN	AQR	61	O60306
TELLQDYMLTLRTKL	CCM2	296	Q9BSQ5
LSAAQLYYLLIRTMK	ADGRG7	546	Q96K78
IIMLLNVLYEKVALL	ANO4	561	Q32M45
ILLNMYASILLLATI	C5AR1	116	P21730
IIMLLNLAYEKIAYL	ANO3	606	Q9BYT9
KIYLQVLSFLLLGLM	SLC16A2	386	P36021
LNFVRLLMLYTRKFE	NUP93	526	Q8N1F7
RTLVSKIYELLFMNL	NBEAL1	1641	Q6ZS30
LIISYEMLLRSLDQI	RAD54B	406	Q9Y620
MAKQYDVLFRLLLIG	RAB15	1	P59190
LYLQDQLDKLRMIIE	QRICH2	1166	Q9H0J4
LARMELFLYLTAILQ	CYP2F1	441	P24903
LLLVALLMLRKYRKD	GUCY2C	446	P25092
FELKLYMIRLGTLEQ	IMP4	251	Q96G21
LYKTLQVQMLDLLDI	IPPK	321	Q9H8X2
RMDLQLHIYQLKTLI	CADPS	1276	Q9ULU8
KTFFVLILLMYLVIL	OR13C6P	26	Q8NH95
KTFFVLILLMYLVIL	OR13C7	26	P0DN81
RHIGYLELLLKLMFV	KIDINS220	566	Q9ULH0
MKALIAALLLITLQY	HRG	1	P04196
MLALAKILLISTLFY	MUC15	1	Q8N387
MALKLVALIYLALQL	GPAA1	496	O43292
LYLIARVMLLHSKLF	KCNN2	266	Q9H2S1
ASVLLIRKLYILMQD	HORMAD2	156	Q8N7B1
AEILMKTLLRNLGFY	HERC1	941	Q15751
YTFLEDMIRVLLSKL	FSIP2	4466	Q5CZC0
FKIQRLLEPRQYMLL	FBXO46	461	Q6PJ61
KLLLFMGIIDILQSY	PIP5K1B	341	O14986
LQLLAYTALGILIMR	DPY19L1	456	Q2PZI1
YTALGILIMRLKLFL	DPY19L1	461	Q2PZI1
LLARKEIEYQELMFL	DNAH12	2356	Q6ZR08
NVKLYDMVLQFLRTL	NELFB	211	Q8WX92
VTLLAAAMLIVFYKL	LRRC4	536	Q9HBW1
VLMIKALELDSNLYR	MYH9	741	P35579
NSLLLLRAELYLTMK	LONRF2	231	Q1L5Z9
LSFPKLIMITDYLLL	INSR	76	P06213
KLNYLDILMRAFIDV	ITGA6	1006	P23229
KTFFVLILLMYLVIL	OR2S2	26	Q9NQN1
MKLLYLFLAILLAIE	DEFB119	1	Q8N690
MELTIFILRLAIYIL	METTL7A	1	Q9H8H3
LLRQLLKYDLFVSMI	MEI1	246	Q5TIA1
LLKVPLMLTFLYLFV	SLC34A1	101	Q06495
LCLMVLAYLQIFRKL	HCRTR2	236	O43614
LEKLMIRLGLFTVLY	FZD8	526	Q9H461
LMKALEYLKLLFTLL	CKAP5	1261	Q14008
AAMVRLRLYDILALL	HEATR5B	666	Q9P2D3
LFYKLRHVMNELIDL	DOCK3	111	Q8IZD9
MILVLRTALNLFFKL	COPA	1101	P53621
FLARKRLLEYMGLQL	ANKMY1	811	Q9P2S6
SRYFLEMQEKLERLL	MAST3	236	O60307
LIIALIQMFKIVLEY	SLC44A5	521	Q8NCS7
LMEIKQLLVILLTYF	CYP7B1	456	O75881
RASLLYFIMNDLSKI	DNAH9	3681	Q9NYC9
RYLGILNSVLLDLMK	CDKL5	261	O76039
IFLILLLVYRMRKKD	SDC2	161	P34741
MAFELLSIDLYELIK	DYRK3	286	O43781
ALYLIRLLMVILEKS	FANCD2	1131	Q9BXW9
EFLVQLKIMDYSLLL	PIP4K2C	271	Q8TBX8
LLMGFSNIQKLRILY	OR14A2	11	Q96R54
LIYLAALMSNLLIIT	OR14A2	31	Q96R54
FYNIIFRRLLKIMNL	PIWIL1	211	Q96J94
IMASLNLLRYLVIKD	GLMN	471	Q92990
SIMLHELIKLLYYAR	UPP1	116	Q16831
IILMLLLFLYINKKF	SYT14	36	Q8NB59
FLLLLVLERLYASPM	THADA	1321	Q6YHU6
RYLVLDLALLFLMGI	TMEM80	126	Q96HE8
LISYFLILNTILKMS	OR5AU1	266	Q8NGC0
EIISLRAFMLLFLKQ	NBEA	676	Q8NFP9
LFLTLLMLEAAYKLL	SMIM40	41	Q5STR5
MTAALLQVLILLYIA	SLC41A1	446	Q8IVJ1
LILMEARLSALYKLE	IARS1	256	P41252
LTYTMILNLLRVDAL	SKIV2L	746	Q15477
LSYLLILVAILRMNS	OR8K3	216	Q8NH51
EILRYMKEFTLLLSA	P2RY14	271	Q15391
ELLTDNRYLLLVLMD	SRP68	116	Q9UHB9
MLGSLYKILENILII	MC2R	71	Q01718
YKILENILIILRNMG	MC2R	76	Q01718
LLNNMELIRKIYSTL	SLC25A13	226	Q9UJS0
LEMLLRLLDTYRDKI	RNF213	821	Q63HN8
MARQKGIFYLTLFLI	ZDHHC9	31	Q9Y397
EKLSDLDYMQFIRLL	MRPS9	211	P82933
LDYMQFIRLLEKLLT	MRPS9	216	P82933
KRCLYFFVLLLMILI	SGCD	31	Q92629
LLLYLAFYIIMKLRS	SIDT1	721	Q9NXL6
MLRYLLKTLLQMNLF	ROBO3	1	Q96MS0
DMEKQLLYLRELLRL	TBC1D16	571	Q8TBP0
YFLMLIILVNAKEVI	TBC1D23	231	Q9NUY8
LKLLSPLMTRYFFLL	VN1R1	6	Q9GZP7
LLTYILLLNMLIALM	TRPV2	631	Q9Y5S1
LMDPNKFLLLVLQRY	UBR1	701	Q8IWV7
LLYRDVMLENLALLS	ZNF548	31	Q8NEK5
ALIGLIFLMVLYLNR	TPBGL	316	P0DKB5
LTFRLNYLLSELKPM	TMTC3	76	Q6ZXV5
RLDFQLMLKIRDTLY	SEMA6D	56	Q8NFY4
ASLVLMVLYLIKKRL	PIGM	151	Q9H3S5
VMLLLYLGIEVIRLF	TMEM216	61	Q9P0N5
SMLKRLARDQLIYLL	VPS33B	16	Q9H267
RMLLDILKFLFIYCL	TRPC4	511	Q9UBN4
VQRIMKYQLLLKDFL	TRIO	2101	O75962
LEKLEAMYRRALLQL	TUSC1	161	Q2TAM9
MLREYQELVSLKLAL	KRT72	406	Q14CN4
IIKYLALQDLMLLSQ	NDC1	326	Q9BTX1