Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	poly(A) binding	PABPC1L2A PABPC4 PABPC1 PABPC1L	2.37e-05	29	117	4	GO:0008143
GeneOntologyMolecularFunction	poly(U) RNA binding	PABPC1L2A PABPC4 PABPC1 PABPC1L	4.53e-05	34	117	4	GO:0008266
GeneOntologyMolecularFunction	poly-purine tract binding	PABPC1L2A PABPC4 PABPC1 PABPC1L	6.37e-05	37	117	4	GO:0070717
GeneOntologyMolecularFunction	poly-pyrimidine tract binding	PABPC1L2A PABPC4 PABPC1 PABPC1L	7.86e-05	39	117	4	GO:0008187
GeneOntologyMolecularFunction	transmembrane receptor protein tyrosine phosphatase activity	PTPRU PTPN6 PTPRD	1.26e-04	17	117	3	GO:0005001
GeneOntologyMolecularFunction	transmembrane receptor protein phosphatase activity	PTPRU PTPN6 PTPRD	1.26e-04	17	117	3	GO:0019198
Domain	PolyA	PABPC4 PABPC1 PABPC1L	2.31e-06	5	116	3	SM00517
Domain	-	PABPC4 PABPC1 PABPC1L	2.31e-06	5	116	3	1.10.1900.10
Domain	PABP	PABPC4 PABPC1 PABPC1L	2.31e-06	5	116	3	PF00658
Domain	PABP_1234	PABPC4 PABPC1 PABPC1L	2.31e-06	5	116	3	IPR006515
Domain	PABC	PABPC4 PABPC1 PABPC1L	2.31e-06	5	116	3	PS51309
Domain	PABP_HYD	PABPC4 PABPC1 PABPC1L	2.31e-06	5	116	3	IPR002004
Domain	Latrophilin	ADGRL2 ADGRL3	1.14e-04	3	116	2	PF02354
Domain	GPCR_2_latrophilin_rcpt_C	ADGRL2 ADGRL3	1.14e-04	3	116	2	IPR003334
Domain	WWE	DTX4 DTX2	2.28e-04	4	116	2	SM00678
Domain	WWE-dom_subgr	DTX4 DTX2	2.28e-04	4	116	2	IPR018123
Domain	TPR-contain_dom	TANC2 SGTB TTC28 P3H3 TRANK1 TMTC3	3.49e-04	150	116	6	IPR013026
Domain	RRM_1	PABPC4 PABPC1 PABPC1L	3.78e-04	23	116	3	SM00361
Domain	RRM_dom_euk	PABPC4 PABPC1 PABPC1L	3.78e-04	23	116	3	IPR003954
Domain	Gal_Lectin	ADGRL2 ADGRL3	3.78e-04	5	116	2	PF02140
Domain	GPCR_2_latrophilin	ADGRL2 ADGRL3	3.78e-04	5	116	2	IPR003924
Domain	Lectin_gal-bd_dom	ADGRL2 ADGRL3	3.78e-04	5	116	2	IPR000922
Domain	SUEL_LECTIN	ADGRL2 ADGRL3	3.78e-04	5	116	2	PS50228
Domain	TPR_REGION	TANC2 SGTB TTC28 P3H3 TRANK1 TMTC3	5.78e-04	165	116	6	PS50293
Domain	TPR	TANC2 SGTB TTC28 P3H3 TRANK1 TMTC3	5.78e-04	165	116	6	PS50005
Domain	Anoct_dimer	ANO2 ANO1	7.87e-04	7	116	2	PF16178
Domain	Anoct_dimer	ANO2 ANO1	7.87e-04	7	116	2	IPR032394
Domain	TPR	TANC2 SGTB TTC28 TRANK1 TMTC3	1.26e-03	129	116	5	SM00028
Domain	PTPc	PTPRU PTPN6 PTPRD	1.44e-03	36	116	3	SM00194
Domain	TPR_repeat	TANC2 SGTB TTC28 TRANK1 TMTC3	1.45e-03	133	116	5	IPR019734
Domain	Anoctamin	ANO2 ANO1	1.67e-03	10	116	2	PF04547
Domain	Anoctamin	ANO2 ANO1	1.67e-03	10	116	2	IPR007632
Domain	TYR_PHOSPHATASE_PTP	PTPRU PTPN6 PTPRD	1.81e-03	39	116	3	PS50055
Domain	-	TANC2 SGTB TTC28 P3H3 TRANK1 TMTC3	1.86e-03	207	116	6	1.25.40.10
Domain	GAIN_dom_N	ADGRL2 ADGRL3	2.03e-03	11	116	2	IPR032471
Domain	GAIN	ADGRL2 ADGRL3	2.03e-03	11	116	2	PF16489
Domain	PTPase_domain	PTPRU PTPN6 PTPRD	2.10e-03	41	116	3	IPR000242
Domain	Y_phosphatase	PTPRU PTPN6 PTPRD	2.10e-03	41	116	3	PF00102
Domain	Ferric_reduct	NOX4 STEAP2	2.42e-03	12	116	2	PF01794
Domain	WWE	DTX4 DTX2	2.42e-03	12	116	2	PF02825
Domain	WWE-dom	DTX4 DTX2	2.42e-03	12	116	2	IPR004170
Domain	WWE	DTX4 DTX2	2.42e-03	12	116	2	PS50918
Domain	Fe3_Rdtase_TM_dom	NOX4 STEAP2	2.42e-03	12	116	2	IPR013130
Domain	OLF	ADGRL2 ADGRL3	2.85e-03	13	116	2	PF02191
Domain	OLF	ADGRL2 ADGRL3	2.85e-03	13	116	2	PS51132
Domain	Olfac-like_dom	ADGRL2 ADGRL3	2.85e-03	13	116	2	IPR003112
Domain	OLF	ADGRL2 ADGRL3	2.85e-03	13	116	2	SM00284
Domain	TPR-like_helical_dom	TANC2 SGTB TTC28 P3H3 TRANK1 TMTC3	3.35e-03	233	116	6	IPR011990
Domain	-	TMPRSS6 CRHBP DMBT1	4.13e-03	52	116	3	2.60.120.290
Domain	TPR_8	TANC2 TTC28 TMTC3	4.36e-03	53	116	3	PF13181
Domain	ARM-type_fold	ARMC7 IPO8 USP9Y ITPR2 PIK3C2G EFR3B UTP20	5.26e-03	339	116	7	IPR016024
Domain	CUB_dom	TMPRSS6 CRHBP DMBT1	5.35e-03	57	116	3	IPR000859
Domain	PTPc_motif	PTPRU PTPN6 PTPRD	5.89e-03	59	116	3	SM00404
Domain	Tyr_Pase_cat	PTPRU PTPN6 PTPRD	5.89e-03	59	116	3	IPR003595
Pubmed	Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.	EPHB6 PRKD2 SRXN1 DMXL2 SORBS2 SGTB TTC28 UBA3 USP9Y TF TUBB2A IQGAP1 ZBTB44 PTPRD CLU LRP1 MRPS9 DLG2 PJA1 TNKS2 REPS2 RSBN1L	4.33e-10	1285	119	22	35914814
Pubmed	TMEM16A-TMEM16B chimaeras to investigate the structure-function relationship of calcium-activated chloride channels.	ANO2 ANO1	1.16e-05	2	119	2	23570556
Pubmed	Developmental expression of the calcium-activated chloride channels TMEM16A and TMEM16B in the mouse olfactory epithelium.	ANO2 ANO1	1.16e-05	2	119	2	24318978
Pubmed	Calcium-activated chloride channels anoctamin 1 and 2 promote murine uterine smooth muscle contractility.	ANO2 ANO1	1.16e-05	2	119	2	24928056
Pubmed	Latrophilin GPCRs direct synapse specificity by coincident binding of FLRTs and teneurins.	ADGRL2 ADGRL3	1.16e-05	2	119	2	30792275
Pubmed	The Cl--channel TMEM16A is involved in the generation of cochlear Ca2+ waves and promotes the refinement of auditory brainstem networks in mice.	ANO2 ANO1	1.16e-05	2	119	2	35129434
Pubmed	Latrophilin GPCR signaling mediates synapse formation.	ADGRL2 ADGRL3	1.16e-05	2	119	2	33646123
Pubmed	Aggregated low-density lipoprotein induces LRP1 stabilization through E3 ubiquitin ligase CHFR downregulation in human vascular smooth muscle cells.	CHFR LRP1	1.16e-05	2	119	2	23241409
Pubmed	{2-[1-(3-Methoxycarbonylmethyl-1H-indol-2-yl)-1-methyl-ethyl]-1H-indol-3-yl}-acetic Acid Methyl Ester Inhibited Hepatocellular Carcinoma Growth in Bel-7402 Cells and Its Resistant Variants by Activation of NOX4 and SIRT3.	NOX4 SIRT3	1.16e-05	2	119	2	25961022
Pubmed	Preassociated apocalmodulin mediates Ca2+-dependent sensitization of activation and inactivation of TMEM16A/16B Ca2+-gated Cl- channels.	ANO2 ANO1	1.16e-05	2	119	2	25489088
Pubmed	Calcium-activated chloride channels (CaCCs) regulate action potential and synaptic response in hippocampal neurons.	ANO2 ANO1	1.16e-05	2	119	2	22500639
Pubmed	Exploring an Alternative Cysteine-Reactive Chemistry to Enable Proteome-Wide PPI Analysis by Cross-Linking Mass Spectrometry.	PRKD2 PABPC1 TUBB2A IQGAP1 MRPS9 DLG2 GNAI1 RSBN1L DYNC1I2	1.27e-05	411	119	9	36652389
Pubmed	Protein interaction network of the mammalian Hippo pathway reveals mechanisms of kinase-phosphatase interactions.	TANC2 SORBS2 OFD1 TTC28 TRIM27 WNK1 TUBB2A AKAP9 EXO1	2.41e-05	446	119	9	24255178
Pubmed	Long-term potentiation modulates synaptic phosphorylation networks and reshapes the structure of the postsynaptic interactome.	DIP2B DMXL2 SORBS2 CLU LRP1 DLG2 GNAI1	2.64e-05	251	119	7	27507650
Pubmed	Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.	TANC2 DIP2B DMXL2 SORBS2 PABPC1 IQGAP1 PTPRD AKAP9 CLU LRP1 DLG2 GNAI1 ARHGEF26	2.71e-05	963	119	13	28671696
Pubmed	Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.	TANC2 PRKD2 EPC2 EP400 TTC28 P3H3 TRIM27 TF CLU MTHFR LRP1 ADGRL2 RSBN1L UNC80	2.92e-05	1116	119	14	31753913
Pubmed	A family of heptahelical receptors with adhesion-like domains: a marriage between two super families.	ADGRL2 ADGRL3	3.47e-05	3	119	2	10994649
Pubmed	Embryonic Poly(A)-Binding Protein Is Required During Early Stages of Mouse Oocyte Development for Chromatin Organization, Transcriptional Silencing, and Meiotic Competence.	PABPC1 PABPC1L	3.47e-05	3	119	2	26134869
Pubmed	Superovulation alters embryonic poly(A)-binding protein (Epab) and poly(A)-binding protein, cytoplasmic 1 (Pabpc1) gene expression in mouse oocytes and early embryos.	PABPC1 PABPC1L	3.47e-05	3	119	2	25034140
Pubmed	The poly(A)-binding protein genes, EPAB, PABPC1, and PABPC3 are differentially expressed in infertile men with non-obstructive azoospermia.	PABPC1 PABPC1L	3.47e-05	3	119	2	26843391
Pubmed	PARylation of BRCA1 limits DNA break resection through BRCA2 and EXO1.	BRCA2 EXO1	3.47e-05	3	119	2	36735534
Pubmed	Putative pore-loops of TMEM16/anoctamin channels affect channel density in cell membranes.	ANO2 ANO1	3.47e-05	3	119	2	23613533
Pubmed	Nuclear relocalisation of cytoplasmic poly(A)-binding proteins PABP1 and PABP4 in response to UV irradiation reveals mRNA-dependent export of metazoan PABPs.	PABPC4 PABPC1	3.47e-05	3	119	2	21940797
Pubmed	Expression patterns of anoctamin 1 and anoctamin 2 chloride channels in the mammalian nose.	ANO2 ANO1	3.47e-05	3	119	2	22314846
Pubmed	Identification of ZNF366 and PTPRD as novel determinants of plasma homocysteine in a family-based genome-wide association study.	PTPRD MTHFR	3.47e-05	3	119	2	19525478
Pubmed	T cells develop normally in the absence of both Deltex1 and Deltex2.	DTX4 DTX2	3.47e-05	3	119	2	16923970
Pubmed	Epab and Pabpc1 are differentially expressed during male germ cell development.	PABPC1 PABPC1L	3.47e-05	3	119	2	22814100
Pubmed	Identification of a dimerization domain in the TMEM16A calcium-activated chloride channel (CaCC).	ANO2 ANO1	3.47e-05	3	119	2	23576756
Pubmed	TMEM16A and TMEM16B Modulate Pheromone-Evoked Action Potential Firing in Mouse Vomeronasal Sensory Neurons.	ANO2 ANO1	3.47e-05	3	119	2	34433575
Pubmed	The multiple actions of black widow spider toxins and their selective use in neurosecretion studies.	ADGRL2 ADGRL3	3.47e-05	3	119	2	15066411
Pubmed	Anoctamin Calcium-Activated Chloride Channels May Modulate Inhibitory Transmission in the Cerebellar Cortex.	ANO2 ANO1	3.47e-05	3	119	2	26558388
Pubmed	Epab is dispensable for mouse spermatogenesis and male fertility.	PABPC1 PABPC1L	3.47e-05	3	119	2	24599567
Pubmed	Epab and Pabpc1 are differentially expressed in the postnatal mouse ovaries.	PABPC1 PABPC1L	3.47e-05	3	119	2	25370180
Pubmed	Association of HFE and TMPRSS6 genetic variants with iron and erythrocyte parameters is only in part dependent on serum hepcidin concentrations.	TMPRSS6 TF	3.47e-05	3	119	2	21785125
Pubmed	alpha-Latrotoxin and its receptors: neurexins and CIRL/latrophilins.	ADGRL2 ADGRL3	3.47e-05	3	119	2	11520923
Pubmed	Ca2+-activated Cl- currents in the murine vomeronasal organ enhance neuronal spiking but are dispensable for male-male aggression.	ANO2 ANO1	3.47e-05	3	119	2	29769308
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	TANC2 DMXL2 WNK1 SHROOM4 FAT2 ARHGAP28 DTX2 TASOR UNC80	5.24e-05	493	119	9	15368895
Pubmed	Peptidic degron in EID1 is recognized by an SCF E3 ligase complex containing the orphan F-box protein FBXO21.	IQGAP1 DMBT1 FBXO21	5.74e-05	22	119	3	26631746
Pubmed	MRG15 binds directly to PALB2 and stimulates homology-directed repair of chromosomal breaks.	EPC2 EP400 BRCA2	6.58e-05	23	119	3	20332121
Pubmed	Hearing function and thresholds: a genome-wide association study in European isolated populations identifies new loci and pathways.	GRM8 PTPRD	6.93e-05	4	119	2	21493956
Pubmed	hSSTR2 expression and octreotide treatment reverses multidrug resistance of BxPC-3 human pancreatic cancer cells.	LRP1 ABCC2	6.93e-05	4	119	2	19885591
Pubmed	FLJ10261 gene, located within the CCND1-EMS1 locus on human chromosome 11q13, encodes the eight-transmembrane protein homologous to C12orf3, C11orf25 and FLJ34272 gene products.	ANO2 ANO1	6.93e-05	4	119	2	12739008
Pubmed	Common Variants and Haplotypes in the TF, TNF-α, and TMPRSS6 Genes Are Associated with Iron Status in a Female Black South African Population.	TMPRSS6 TF	6.93e-05	4	119	2	25809685
Pubmed	Latrophilin-2 and latrophilin-3 are redundantly essential for parallel-fiber synapse function in cerebellum.	ADGRL2 ADGRL3	6.93e-05	4	119	2	32202499
Pubmed	An embryonic poly(A)-binding protein (ePAB) is expressed in mouse oocytes and early preimplantation embryos.	PABPC1 PABPC1L	6.93e-05	4	119	2	15630085
Pubmed	Influence of cancer-related gene polymorphisms on clinicopathological features in colorectal cancer.	MTHFR EXO1	6.93e-05	4	119	2	18205772
Pubmed	TMPRSS6, but not TF, TFR2 or BMP2 variants are associated with increased risk of iron-deficiency anemia.	TMPRSS6 TF	6.93e-05	4	119	2	22323359
Pubmed	Methylation of tumor suppressor gene CDH13 and SHP1 promoters and their epigenetic regulation by the UHRF1/PRMT5 complex in endometrial carcinoma.	PTPN6 UHRF1	6.93e-05	4	119	2	26597461
Pubmed	Protein kinase D regulates positive selection of CD4+ thymocytes through phosphorylation of SHP-1.	PRKD2 PTPN6	6.93e-05	4	119	2	27670070
Pubmed	Association between single nucleotide polymorphisms of drug resistance-associated genes and response to chemotherapy in advanced ovarian cancer.	LRP1 ABCC2	6.93e-05	4	119	2	16821592
Pubmed	Methyl group metabolism gene polymorphisms as modifier of breast cancer risk in Italian BRCA1/2 carriers.	BRCA2 MTHFR	6.93e-05	4	119	2	17151928
Pubmed	Changes in brain gene expression shared by scrapie and Alzheimer disease.	TF CLU	6.93e-05	4	119	2	2780570
Pubmed	Transcriptome characterization elucidates signaling networks that control human ES cell growth and differentiation.	EPHB6 PTBP3 SORBS2 SRP19 PTPRU ZBTB44 TRANK1 ASF1B MTHFR EXO1 UHRF1 EIF2AK4 TMEM68 RSBN1L	7.29e-05	1215	119	14	15146197
Pubmed	Mammalian APE1 controls miRNA processing and its interactome is linked to cancer RNA metabolism.	DIP2B PTPRU PABPC1 NDUFS1 ZBTB44 CHFR UHRF1 DMBT1 KIF13A FBXO21 DYNC1I2 C19orf25	8.18e-05	925	119	12	28986522
Pubmed	The composition of Staufen-containing RNA granules from human cells indicates their role in the regulated transport and translation of messenger RNAs.	PABPC1 TUBB2A IQGAP1	8.50e-05	25	119	3	15121898
Pubmed	Protein-protein interactions between large proteins: two-hybrid screening using a functionally classified library composed of long cDNAs.	SORBS2 EP400 TTC28 FBXO21 TASOR	8.77e-05	130	119	5	12421765
Pubmed	KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.	TANC2 DMXL2 SORBS2 PABPC4 TF PABPC1 NDUFS1 TUBB2A LACTB IQGAP1 ITPR2 CLU MRPS9 DLG2 GNAI1	1.14e-04	1431	119	15	37142655
Pubmed	HIV- 1 protease inhibits Cap- and poly(A)-dependent translation upon eIF4GI and PABP cleavage.	PABPC4 PABPC1	1.15e-04	5	119	2	19956697
Pubmed	G-protein alpha subunit interaction and guanine nucleotide dissociation inhibitor activity of the dual GoLoco motif protein PCP-2 (Purkinje cell protein-2).	PTPRU GNAI1	1.15e-04	5	119	2	16298104
Pubmed	Variants in the GH-IGF axis confer susceptibility to lung cancer.	AKAP9 BRCA2	1.15e-04	5	119	2	16741161
Pubmed	Methionine-dependence phenotype in the de novo pathway in BRCA1 and BRCA2 mutation carriers with and without breast cancer.	BRCA2 MTHFR	1.15e-04	5	119	2	18842997
Pubmed	MKRN3-mediated ubiquitination of Poly(A)-binding proteins modulates the stability and translation of GNRH1 mRNA in mammalian puberty.	PABPC4 PABPC1	1.15e-04	5	119	2	33744966
Pubmed	Identification of a common variant in the TFR2 gene implicated in the physiological regulation of serum iron levels.	TMPRSS6 TF	1.15e-04	5	119	2	21208937
Pubmed	Ca2+-activated Cl− currents are dispensable for olfaction.	ANO2 ANO1	1.15e-04	5	119	2	21516098
Pubmed	Embryonic Poly(A)-Binding Protein (EPAB) Is Required for Granulosa Cell EGF Signaling and Cumulus Expansion in Female Mice.	PABPC1 PABPC1L	1.15e-04	5	119	2	26492470
Pubmed	Association of CR1, CLU and PICALM with Alzheimer's disease in a cohort of clinically characterized and neuropathologically verified individuals.	TF CLU MTHFR	1.20e-04	28	119	3	20534741
Pubmed	In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.	GARIN5B PTBP3 PABPC4 PABPC1 NDUFS1 FER1L6 IQGAP1 MRPS9 DLG2 PABPC1L GNAI1 EIF2AK4 ABCC2 TASOR DYNC1I2	1.24e-04	1442	119	15	35575683
Pubmed	A Human Tyrosine Phosphatase Interactome Mapped by Proteomic Profiling.	PRKD2 DIP2B IPO8 PTPRU TF PTPN6 PTPRD TMTC3 LRP1 GNAI1 ADGRL2 FBXO21	1.33e-04	974	119	12	28675297
Pubmed	Elucidation of the BMI1 interactome identifies novel regulatory roles in glioblastoma.	DIP2B PABPC1L2A PABPC4 LACTB IQGAP1 ITPR2 AKAP9	1.44e-04	329	119	7	34316702
Pubmed	Methotrexate (MTX) pathway gene polymorphisms and their effects on MTX toxicity in Caucasian and African American patients with rheumatoid arthritis.	MTHFR ABCC2	1.73e-04	6	119	2	18381794
Pubmed	Assignment of a novel protein tyrosine phosphatase gene (Hcph) to mouse chromosome 6.	PTPN6 FGF6	1.73e-04	6	119	2	1427910
Pubmed	Identification and characterization of TMEM16E and TMEM16F genes in silico.	ANO2 ANO1	1.73e-04	6	119	2	15067359
Pubmed	HIV-1 envelope protein gp120 affects phenotype and function of monocytes in vitro.	CD3D FCGRT	1.73e-04	6	119	2	8145026
Pubmed	Single-nucleotide polymorphisms in NAGNAG acceptors are highly predictive for variations of alternative splicing.	UBA3 DTX2	1.73e-04	6	119	2	16400609
Pubmed	The eukaryotic polypeptide chain releasing factor (eRF3/GSPT) carrying the translation termination signal to the 3'-Poly(A) tail of mRNA. Direct association of erf3/GSPT with polyadenylate-binding protein.	PABPC4 PABPC1	1.73e-04	6	119	2	10358005
Pubmed	Embryonic poly(A)-binding protein is differently expressed and interacts with the messenger RNAs in the mouse oocytes and early embryos.	PABPC1 PABPC1L	1.73e-04	6	119	2	30302808
Pubmed	The calcium-independent receptor for alpha-latrotoxin from human and rodent brains interacts with members of the ProSAP/SSTRIP/Shank family of multidomain proteins.	ADGRL2 ADGRL3	1.73e-04	6	119	2	10964907
Pubmed	Fyn Regulates Binding Partners of Cyclic-AMP Dependent Protein Kinase A.	PABPC4 PABPC1 TUBB2A AKAP9	1.85e-04	82	119	4	30274258
Pubmed	A BioID-Derived Proximity Interactome for SARS-CoV-2 Proteins.	TANC2 IPO8 TRIM27 NDUFS1 TMTC3 EFR3B GNAI1 ABCC2 TMEM68 KIF13A	1.89e-04	719	119	10	35337019
Pubmed	LCP1 preferentially binds clasped αMβ2 integrin and attenuates leukocyte adhesion under flow.	DIP2B EIPR1 WNK1 PABPC1 IQGAP1 PTPN6 DYNC1I2	1.89e-04	344	119	7	30333137
Pubmed	Characterization of the interactome of the human MutL homologues MLH1, PMS1, and PMS2.	USP9Y AKAP9 BRCA2 EXO1	2.33e-04	87	119	4	17148452
Pubmed	K48- and K63-linked ubiquitin chain interactome reveals branch- and length-specific ubiquitin interactors.	SRXN1 TRIM27 LACTB MRPS9 UHRF1 DTX2 DMBT1 FBXO21 RHOF	2.41e-04	604	119	9	38803224
Pubmed	Signal recognition particle protein 19 is imported into the nucleus by importin 8 (RanBP8) and transportin.	IPO8 SRP19	2.41e-04	7	119	2	11682607
Pubmed	Candidate Gene of NOS3, MMP3, AGT, and AGT1R and Pathway Analyses for Platelet Reactivity and Clinical Outcomes of Repeat Revascularization After First PCI in Chinese Patients.	ITPR2 GNAI1	2.41e-04	7	119	2	34860335
Pubmed	ANOs 3-7 in the anoctamin/Tmem16 Cl- channel family are intracellular proteins.	ANO2 ANO1	2.41e-04	7	119	2	22075693
Pubmed	CRIPT, a novel postsynaptic protein that binds to the third PDZ domain of PSD-95/SAP90.	TUBB2A DLG2	2.41e-04	7	119	2	9581762
Pubmed	Chromosomal localization of three human poly(A)-binding protein genes and four related pseudogenes.	PABPC4 PABPC1	2.41e-04	7	119	2	10543404
Pubmed	Novel associations of CPS1, MUT, NOX4, and DPEP1 with plasma homocysteine in a healthy population: a genome-wide evaluation of 13 974 participants in the Women's Genome Health Study.	NOX4 MTHFR	2.41e-04	7	119	2	20031578
Pubmed	HDLBP Promotes Hepatocellular Carcinoma Proliferation and Sorafenib Resistance by Suppressing Trim71-dependent RAF1 Degradation.	PTBP3 EP400 PABPC4 SRP19 CGGBP1 TBC1D8B PABPC1 LACTB IQGAP1 AKAP9 UHRF1 EIF2AK4 FBXO21 RSBN1L	2.55e-04	1371	119	14	36244648
Pubmed	Human plasma N-glycoproteome analysis by immunoaffinity subtraction, hydrazide chemistry, and mass spectrometry.	TF OPTC FAT2 CLU NECTIN1 LRP1	2.65e-04	257	119	6	16335952
Pubmed	Generation and analysis of 280,000 human expressed sequence tags.	SORBS2 WNK1 NDUFS1 LACTB CAPN8 UHRF1 KIF13A	2.85e-04	368	119	7	8889549
Pubmed	The anoctamin family: TMEM16A and TMEM16B as calcium-activated chloride channels.	ANO2 ANO1	3.21e-04	8	119	2	21984732
Pubmed	Near-Infrared Luciferase Complementation Assay with Enhanced Bioluminescence for Studying Protein-Protein Interactions and Drug Evaluation Under Physiological Conditions.	PABPC4 PABPC1	3.21e-04	8	119	2	36135776
Pubmed	Expression and function of epithelial anoctamins.	ANO2 ANO1	3.21e-04	8	119	2	20056604
Pubmed	Expression of TMEM16 paralogs during murine embryogenesis.	ANO2 ANO1	3.21e-04	8	119	2	18729231
Pubmed	Multi-factor dimensionality reduction applied to a large prospective investigation on gene-gene and gene-environment interactions.	BRCA2 MTHFR	3.21e-04	8	119	2	16956909
Pubmed	Common genetic variation and susceptibility to partial epilepsies: a genome-wide association study.	PTPRD ADGRL3	3.21e-04	8	119	2	20522523
Pubmed	A novel cytokine-inducible gene CIS encodes an SH2-containing protein that binds to tyrosine-phosphorylated interleukin 3 and erythropoietin receptors.	TF IL3RA	3.21e-04	8	119	2	7796808
Pubmed	Embryonic poly(A)-binding protein (EPAB) is required for oocyte maturation and female fertility in mice.	PABPC1 PABPC1L	3.21e-04	8	119	2	22621333
Pubmed	Proteomic analysis identifies dysfunction in cellular transport, energy, and protein metabolism in different brain regions of atypical frontotemporal lobar degeneration.	TANC2 NDUFS1 TUBB2A GNAI1	3.53e-04	97	119	4	22360420
Interaction	PTPRS interactions	RHOJ PTPRU TUBB2A OPTC PTPN6 PTPRD CLU FCGRT	3.11e-06	153	117	8	int:PTPRS
Interaction	PTPRF interactions	RHOJ PTPRU LACTB OPTC PTPN6 PTPRD CLU FCGRT RHOF	8.85e-06	233	117	9	int:PTPRF
Interaction	RSPH1 interactions	SRXN1 USP9Y TF TUBB2A ZBTB44 PTPRD CLU	1.14e-05	131	117	7	int:RSPH1
Interaction	FLOT1 interactions	DIP2B SORBS2 SGTB OFD1 EP400 RHOJ TUBB2A IQGAP1 EFR3B FGD5 ADGRL2 RHOF	2.09e-05	475	117	12	int:FLOT1
GeneFamily	Adhesion G protein-coupled receptors, subfamily L	ADGRL2 ADGRL3	1.33e-04	4	86	2	918
GeneFamily	Tetratricopeptide repeat domain containing\|Bardet-Biedl syndrome associated\|BBSome	TANC2 SGTB TTC28 TRANK1 TMTC3	2.20e-04	115	86	5	769
GeneFamily	Anoctamins	ANO2 ANO1	9.82e-04	10	86	2	865
GeneFamily	Ring finger proteins	TRIM27 DTX4 CHFR UHRF1 DTX2 PJA1	1.99e-03	275	86	6	58
GeneFamily	RNA binding motif containing	PTBP3 PABPC1L2A PABPC4 PABPC1 PABPC1L	3.48e-03	213	86	5	725
GeneFamily	Rho family GTPases	RHOJ RHOF	4.02e-03	20	86	2	390
GeneFamily	Protein tyrosine phosphatases, receptor type	PTPRU PTPRD	4.43e-03	21	86	2	813
ToppCell	COVID-19-Endothelial_cells-Endothelial_cells_(general)\|COVID-19 / group, cell type (main and fine annotations)	ANO2 SORBS2 TTC28 RHOJ SHROOM4 FGD5 ADGRL2 ADGRL3	4.59e-08	190	119	8	812e11314c76c0179fbe5a9bea29b41ce5cbc93d
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell_cycling-Cycling_Connecting_Tubule_Cell_S-high\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	LAMA3 GRM8 BRCA2 ASF1B EFR3B EXO1 UHRF1	3.38e-07	167	119	7	108ae6221c6edc63c0ec42c42471b3a15a594043
ToppCell	PND14-Immune-Immune_Myeloid-Monocytic-Macrophage-AM-AM_prolif\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	DMXL2 FADS6 ASF1B LRP1 EXO1 UHRF1 UTP20	4.82e-07	176	119	7	450c25ec5eeb65425f904e0a25aaafdf5682ef9c
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ANO2 CAPN8 TRANK1 PTPRD PIK3C2G UNC80 ADGRL3	6.50e-07	184	119	7	2cbed6462fea2622871bb7e49b0df3d984239281
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ANO2 CAPN8 TRANK1 PTPRD PIK3C2G UNC80 ADGRL3	6.50e-07	184	119	7	ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCell	Serous\|World / shred by cell class for bronchial biopsy	SORBS2 TNFSF18 RHOJ ANO1 CLU DMBT1 UNC80	6.50e-07	184	119	7	09d0d1525c11dd326efd942684c03f79d992cf3b
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ANO2 CAPN8 TRANK1 PTPRD PIK3C2G UNC80 ADGRL3	6.50e-07	184	119	7	2b19a8c5f823e00812908b23e66bb4e563278aff
ToppCell	Children_(3_yrs)-Endothelial-capillary_endothelial_cell_(Cap1)-D046\|Children_(3_yrs) / Lineage, Cell type, age group and donor	ANO2 SORBS2 TTC28 RHOJ SHROOM4 ADGRL2 ADGRL3	7.51e-07	188	119	7	117dc80fa940e6aa1b0187a43fdde33f3fcb578f
ToppCell	metastatic_Brain-Endothelial_cells\|metastatic_Brain / Location, Cell class and cell subclass	ANO2 RHOJ NOX4 SHROOM4 FGD5 ADGRL2 IL3RA	1.06e-06	198	119	7	97ef7946ef11ac93318c1dd46b548dc01e5a6aba
ToppCell	metastatic_Brain-Endothelial_cells-Tumor_ECs\|metastatic_Brain / Location, Cell class and cell subclass	ANO2 RHOJ NOX4 SHROOM4 FGD5 ADGRL2 IL3RA	1.06e-06	198	119	7	5e274f29cc796dae7d64d6035e904816c25f9914
ToppCell	10x_5'_v1-Non-neoplastic-Glial-Neuronal-Oligodendrocyte-Oligodendrocyte\|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	TF SHROOM4 PTPRD NECTIN1 EFR3B DLG2 GNAI1	1.10e-06	199	119	7	5d2e85e40b6b52b1809e680b952913d77215b3d0
ToppCell	10x_5'_v1-Non-neoplastic-Glial-Neuronal-Oligodendrocyte\|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	TF SHROOM4 PTPRD NECTIN1 EFR3B DLG2 GNAI1	1.10e-06	199	119	7	9dd4b17fb8c70ab9e126b23b72600463f3db832d
ToppCell	kidney_cells-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	SORBS2 EP400 IQGAP1 AKAP9 CLU DEPDC5 PABPC1L	1.10e-06	199	119	7	174f6013af6eafa577f84205a62927f2b367fda3
ToppCell	10x_5'_v1-Non-neoplastic-Glial-Neuronal-Oligodendrocyte-Oligodendrocyte-Z\|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	TF SHROOM4 PTPRD NECTIN1 EFR3B DLG2 GNAI1	1.10e-06	199	119	7	6fb5f931e6217142de38c1fffc011e63bda4772b
ToppCell	10x_5'_v1-Non-neoplastic-Glial-Neuronal\|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	TF SHROOM4 PTPRD NECTIN1 EFR3B DLG2 GNAI1	1.10e-06	199	119	7	1bb5797e8e0552bf9b44bf4c958d1aa6dbe6c756
ToppCell	facs-Lung-Endomucin-24m-Endothelial-Capillary_Type_1_Cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PKD2L1 USP9Y CRHBP DMBT1 ABCC2 UNC80	2.60e-06	145	119	6	96712c68ab759d7ade0d912581a1a7c25dc6def8
ToppCell	ileum-BEST4+_Enterocytes\|ileum / shred on tissue and cell subclass	FSTL4 STEAP2 PABPC1 ITPR2 NECTIN1 RSBN1L	3.68e-06	154	119	6	608e9c982125e0c2c15b86b1920813845a0db81f
ToppCell	facs-Lung-24m-Endothelial-capillary_endothelial-capillary_endothelial_cell-capillary_type_1_endothelial_cell\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	PKD2L1 USP9Y CRHBP DMBT1 ABCC2 UNC80	4.93e-06	162	119	6	bf886e22ff2a20353499004b53f25fb9e6574896
ToppCell	PND01-Endothelial-Endothelial_lymphatic-Lymphatic_EC-LEC-LEC_prolif\|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	SORBS2 PKD2L1 TBC1D8B ASF1B EXO1 UHRF1	7.92e-06	176	119	6	a9e77681bcd36c382d53eb6f771349d55f98d744
ToppCell	LPS-IL1RA+antiTNF\|World / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	SORBS2 LAMA3 USP9Y CLU DLG2 ARHGEF26	8.18e-06	177	119	6	b7fee75de7e96924af488a5baa2334711889ae7c
ToppCell	COPD-Endothelial-VE_Venous\|World / Disease state, Lineage and Cell class	ANO2 SORBS2 RHOJ SHROOM4 CLU ADGRL2	8.72e-06	179	119	6	9968da1adcb561d9bf167a42ab5d9de85c071c4a
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_S-high\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	LAMA3 GRM8 BRCA2 ASF1B EXO1 UHRF1	8.72e-06	179	119	6	88d44b04eb5c079531db663ed98ddb20b60feb9a
ToppCell	Control-Endothelial_cells-Capillary_endothelial_cells\|Control / group, cell type (main and fine annotations)	FSTL4 GRM8 SHROOM4 FGD5 ADGRL2 ADGRL3	9.00e-06	180	119	6	b043f9ffb9a4cd427a15bebb86a711c7b08866e8
ToppCell	tumor_Lymph_Node_/_Brain-Endothelial_cells\|tumor_Lymph_Node_/_Brain / Location, Cell class and cell subclass	ANO2 RHOJ SHROOM4 FGD5 ADGRL2 IL3RA	9.59e-06	182	119	6	d7cce5dd7046f06bf40f00c9dbfa610722b03333
ToppCell	Children_(3_yrs)-Endothelial-alveolar_capillary_endothelial_cell_(Cap2;_aerocyte)-D046\|Children_(3_yrs) / Lineage, Cell type, age group and donor	FSTL4 NOX4 GRM8 FGD5 ADGRL2 ADGRL3	9.59e-06	182	119	6	a20017b6a4f9a6a29e090e4dbd7c02ed1495bd50
ToppCell	droplet-Lung-21m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell\|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	TANC2 SORBS2 LAMA3 SHROOM4 CLU FGD5	9.59e-06	182	119	6	c7f2d24697affa530b748ab32b1d40bdc1bdc20a
ToppCell	droplet-Lung-21m-Endothelial-arterial_endothelial\|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	TANC2 SORBS2 LAMA3 SHROOM4 CLU FGD5	9.59e-06	182	119	6	d95635b74e8cd8bc00bfe40340806b59fb9bee43
ToppCell	COPD-Endothelial-VE_Venous\|COPD / Disease state, Lineage and Cell class	ANO2 SORBS2 RHOJ SHROOM4 CLU ADGRL2	1.02e-05	184	119	6	44d716e7ba46a1ed03f5992631289653f8fd7d5e
ToppCell	10x_5'_v1-Non-neoplastic-Myeloid-Mono-Mono_anti-infl-Z\|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	DMXL2 TBC1D8B PTPRD DLG2 FGD5 ABCC2	1.08e-05	186	119	6	f73cb91e74a806858650ae97f543fc779ba4cff8
ToppCell	10x_5'_v1-Non-neoplastic-Myeloid-Mono-Mono_anti-infl\|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	DMXL2 TBC1D8B PTPRD DLG2 FGD5 ABCC2	1.08e-05	186	119	6	8694ca16c9780729f4fba67ba20e35745f1eb4e9
ToppCell	10x3'2.3-week_17-19-Endothelial-stroma-proliferating_EC\|week_17-19 / cell types per 3 fetal stages;per 3',per 5'	TTC28 RHOJ LAMA3 SHROOM4 ARHGAP28 FGD5	1.08e-05	186	119	6	a844d4f79e0ad5d6c60a4488ffd8f4f21b7eed04
ToppCell	COVID-19-Endothelial_cells-Pulmonary_venous_endothelial_cells\|COVID-19 / group, cell type (main and fine annotations)	ANO2 SORBS2 RHOJ SHROOM4 FGD5 ADGRL2	1.12e-05	187	119	6	2d20193a6cacdfa4877457c97b0077408942186c
ToppCell	Adult-Endothelial-capillary_endothelial_cell_(Cap1)-D175\|Adult / Lineage, Cell type, age group and donor	ANO2 TTC28 RHOJ SHROOM4 FGD5 ADGRL2	1.12e-05	187	119	6	f3548817f2fded5978137bb252cb628ac199e4f6
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	SORBS2 TTC28 NOX4 MB21D2 PTPRD DLG2	1.12e-05	187	119	6	9d77ca45f7563bd6f2a0c1be5d99d93ad30983f7
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell_cycling\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	BRCA2 PIK3C2G ASF1B EFR3B EXO1 UHRF1	1.12e-05	187	119	6	057569c9437219ecc396aa6e673b1178a2273837
ToppCell	tumor_Lymph_Node_/_Brain-Endothelial_cells-Tumor_ECs\|tumor_Lymph_Node_/_Brain / Location, Cell class and cell subclass	ANO2 RHOJ SHROOM4 FGD5 ADGRL2 IL3RA	1.12e-05	187	119	6	be5f8c5802b0fa8cc1e274fdf06b13eb8ceb8ad4
ToppCell	Control-Endothelial_cells\|Control / group, cell type (main and fine annotations)	ANO2 TTC28 RHOJ SHROOM4 FGD5 ADGRL2	1.15e-05	188	119	6	3953b08abfea93468fc8d177bdb16ca7c6ffa1ab
ToppCell	nucseq-Endothelial-Endothelial_Vascular-Endothelial_capillary-CAP2\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	FSTL4 GRM8 SHROOM4 FGD5 ADGRL2 ADGRL3	1.19e-05	189	119	6	b6b4da51bc7f2c13a2f940540fdc61027d084835
ToppCell	LA-13._Vascular_Smooth_Muscle\|World / Chamber and Cluster_Paper	ANO1 LAMA3 ARHGAP28 KIF13A ARHGEF26 ADGRL3	1.19e-05	189	119	6	6b3e88751b95fc2173f2c3d5061ed632d0c5f01c
ToppCell	Control-Endothelial-VE_Venous\|Endothelial / Disease state, Lineage and Cell class	ANO2 SORBS2 ITPR2 SHROOM4 MB21D2 CLU	1.22e-05	190	119	6	4e30155203b4a8c5e496fcbe9348b67b98ebc625
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	SORBS2 TTC28 NOX4 MB21D2 PTPRD DLG2	1.22e-05	190	119	6	989d4eefd22d66ecb857836f8fdbcf41e3047f84
ToppCell	Children_(3_yrs)-Endothelial-alveolar_capillary_endothelial_cell_(Cap2;_aerocyte)-D139\|Children_(3_yrs) / Lineage, Cell type, age group and donor	FSTL4 NOX4 SHROOM4 FGD5 ADGRL2 ADGRL3	1.22e-05	190	119	6	0a351609a72fd638c84b2435782e312ee6a33aac
ToppCell	human_hepatoblastoma-Endothelial_cells\|World / Sample and Cell Type and Tumor Cluster (all cells)	TANC2 ANO2 RHOJ NOX4 FGD5 ADGRL2	1.22e-05	190	119	6	8d6ef93d69e96cd6921816d152bea3b0710cf147
ToppCell	COVID-19-Endothelial_cells\|COVID-19 / group, cell type (main and fine annotations)	ANO2 TTC28 RHOJ SHROOM4 FGD5 ADGRL2	1.22e-05	190	119	6	9fbd92cd6d4683b2490504d29c43cf42020433d4
ToppCell	10x5'v1-week_12-13-Endothelial-stroma-tip_EC\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	RHOJ NOX4 SHROOM4 ARHGAP28 FGD5 ADGRL2	1.26e-05	191	119	6	cf1a67b7c0d5c0dc5d4d59faf9d9b1a3a1fb00e0
ToppCell	Children_(3_yrs)-Endothelial-alveolar_capillary_endothelial_cell_(Cap2;_aerocyte)\|Children_(3_yrs) / Lineage, Cell type, age group and donor	FSTL4 NOX4 GRM8 FGD5 ADGRL2 ADGRL3	1.26e-05	191	119	6	f229abf69a1217194f74b0502486907e07dba989
ToppCell	Control-Endothelial-VE_Venous\|Control / Disease state, Lineage and Cell class	ANO2 SORBS2 RHOJ SHROOM4 CLU ADGRL2	1.26e-05	191	119	6	617546cf4883dedf3323e03a53ba5adec334cf8e
ToppCell	Fetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_2\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	LAMA3 SHROOM4 PTPRD PIK3C2G DLG2 DMBT1	1.30e-05	192	119	6	fb2f0e897228f808d9ff734ad05e9b49dc38fa50
ToppCell	10x_3'_v2v3-Non-neoplastic-Glial-Neuronal-Oligodendrocyte-Oligodendrocyte-C\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	TF PTPRD DTX4 DLG2 GNAI1 REPS2	1.30e-05	192	119	6	3ce5dbde41aeb73d49f2c7991d34682f0827fa5a
ToppCell	renal_cortex_nuclei\|World / Celltypes from Cells and Nuclei per compartment and clinical group	DIP2B SORBS2 TTC28 NOX4 PTPRD DLG2	1.30e-05	192	119	6	e8cc4d08fcfceeab75a02558817e4ccd7dbafe3a
ToppCell	IPF-Endothelial-VE_Venous\|IPF / Disease state, Lineage and Cell class	ANO2 SORBS2 RHOJ SHROOM4 CLU ADGRL2	1.34e-05	193	119	6	29a655fa80feaabe846c90a28363b037e22d24ae
ToppCell	IPF-Endothelial-VE_Venous\|World / Disease state, Lineage and Cell class	ANO2 SORBS2 RHOJ SHROOM4 CLU ADGRL2	1.34e-05	193	119	6	ef66a46e7ab44fcc4005a23416e6da478a4cce37
ToppCell	Children_(3_yrs)-Endothelial-capillary_endothelial_cell_(Cap1)\|Children_(3_yrs) / Lineage, Cell type, age group and donor	ANO2 TTC28 RHOJ SHROOM4 ADGRL2 ADGRL3	1.38e-05	194	119	6	71ac69cdf7a08ca3ddfb5b492b14ac56b6cd5e5d
ToppCell	10x3'2.3-week_17-19-Mesenchymal_fibro-stroma-endosteal_fibroblast\|week_17-19 / cell types per 3 fetal stages;per 3',per 5'	SORBS2 ANO1 STEAP2 CLU LRP1 ARHGAP28	1.38e-05	194	119	6	69362e13158033de44f90f3773db6c0f27de8cb3
ToppCell	Endothelial-endothelial_cell_of_vein\|World / Lineage, Cell type, age group and donor	ANO2 SORBS2 RHOJ SHROOM4 FGD5 ADGRL2	1.38e-05	194	119	6	3cbd9622a68e89add90e589867d88c83c5a33476
ToppCell	IPF-Endothelial-VE_Venous\|Endothelial / Disease state, Lineage and Cell class	ANO2 SORBS2 ITPR2 SHROOM4 CLU GNAI1	1.38e-05	194	119	6	e8a9005963704286bcc50785bda8d7d63ec001b1
ToppCell	droplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TTC28 TMPRSS6 IQGAP1 AKAP9 TNKS2 UNC80	1.42e-05	195	119	6	3e519cffa6144a62b06124642a14c9ff39b76554
ToppCell	droplet-Mammary_Gland-nan-21m-Epithelial\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TANC2 SRXN1 ANO1 LAMA3 TUBB2A NECTIN1	1.50e-05	197	119	6	f4dad4423384a2a25e064c849ffccf2811573be0
ToppCell	COVID-19-lung-Capillary_1\|lung / Disease (COVID-19 only), tissue and cell type	ANO2 TTC28 RHOJ SHROOM4 FGD5 ADGRL2	1.50e-05	197	119	6	7e86ff9dafcbaaa7464d61484dd48bfeb7eae6e4
ToppCell	10x5'v1-week_12-13-Endothelial-stroma\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	RHOJ NOX4 SHROOM4 ARHGAP28 FGD5 ADGRL2	1.55e-05	198	119	6	122215d9288533ad03562cf777e846504863df9a
ToppCell	10x5'v1-week_12-13-Endothelial\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	RHOJ NOX4 SHROOM4 ARHGAP28 FGD5 ADGRL2	1.55e-05	198	119	6	307dd09e6bc820a148f3000f18dae7aedba4be0b
ToppCell	Tracheal-10x3prime_v2-Epithelial-Epi_submucosal-gland-SMG_Mucous\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	ANO1 TBC1D8B TF CAPN8 DTX4 DLG2	1.55e-05	198	119	6	2ae9564da9913510141994262f3739eb095e0a68
ToppCell	Bronchial-NucSeq-Endothelial-Endothelia_vascular-VE_pulmonary_venous\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	ANO2 SHROOM4 CLU FGF6 FGD5 ADGRL2	1.59e-05	199	119	6	3a4deea6e11a0555d27497b7c9983350797aac69
ToppCell	5'-Adult-SmallIntestine-Endothelial-blood_vessel_EC-Mature_venous_EC\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ANO2 RHOJ CLU FGD5 ADGRL2 IL3RA	1.59e-05	199	119	6	07bda4ac8ffdce1a865ebc99e46c2a27925ff7a8
ToppCell	10x3'2.3-week_14-16-Endothelial-stroma-tip_EC\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	RHOJ CRHBP SHROOM4 ARHGAP28 FGD5 ADGRL2	1.59e-05	199	119	6	1c69395c9305b6ecb0a826d46c8e8ec95795ad6d
ToppCell	Fetal_brain-fetalBrain_Zhong_nature-GW16-Neuronal-Neurons\|GW16 / Sample Type, Dataset, Time_group, and Cell type.	EPHB6 TTC28 TUBB2A PTPRD AKAP9 GNAI1	1.59e-05	199	119	6	ae575ed7582f2a4218f6cbcbf5f7f0ce7a5bc26b
ToppCell	LPS_IL1RA-Epithelial_airway-airway_epithelial\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	ZFAT TF CRHBP CFAP65 CLU RSPH10B	1.64e-05	200	119	6	cf191104484bfb2b9f87de416b9453135f8833c1
ToppCell	LPS_IL1RA-Epithelial_airway\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	ZFAT TF CRHBP CFAP65 CLU RSPH10B	1.64e-05	200	119	6	a5ae33dd4dc1ff6e1a1eec22c4d523d5ab657607
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW08-Neuronal\|GW08 / Sample Type, Dataset, Time_group, and Cell type.	SORBS2 TUBB2A AKAP9 EFR3B	1.89e-05	59	119	4	74590437b1d9a2a8fe56d79b2e66803528b81298
ToppCell	LPS-IL1RA+antiTNF-Epithelial_alveolar-AT_1-Airway\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	TF DTX4 CD101 EFR3B EXO1	2.08e-05	124	119	5	a7b7d8b14d1218194da8fcf69b4780b6e9469332
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Glomerular_Capillary_Endothelial_Cell_prolif\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	SLC46A2 CRHBP EXO1 UHRF1 DMBT1	4.56e-05	146	119	5	281144e293e8c93a425c2606d2188cb2838e667f
ToppCell	facs-Liver-Non-hepatocytes-24m-Lymphocytic-CD8-positive,_alpha-beta_T_cell\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ANO2 ARMC7 CRHBP CD3D CD101	4.86e-05	148	119	5	d44f6c5fc8d1fce4046598030a48fa57ed520a6a
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_S-high\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	BRCA2 ASF1B EXO1 UHRF1 RSPH10B	6.24e-05	156	119	5	955547dfeb1b1ad4957b4338701055726b22619f
ToppCell	PND03-Immune-Immune_Myeloid-Monocytic-Macrophage-iMON-iMON_prolif\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ZFAT FADS6 PTPN6 ASF1B UHRF1	6.43e-05	157	119	5	eea53cf8d8a607264e1ee00b7a97c94bcf2ac80d
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	BRCA2 ASF1B CD101 EXO1 UHRF1	6.43e-05	157	119	5	1ccb07a38d3fb606ee5fbc0437655f49baaaa62c
ToppCell	droplet-Liver-HEPATOCYTES-1m-Epithelial-Hepatocyte_(Pericentral)\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SRXN1 TMPRSS6 PTPRD ABCC2 FBXO21	7.04e-05	160	119	5	c42bcc6c7d113f0db43febb088b75ca4ac7cb7a3
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Connecting_Tubule_Principal_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	FSTL4 WNK1 PIK3C2G DLG2 ADGRL2	7.46e-05	162	119	5	285e6d553f485fd9f1075c4e1b940da251b5ea35
ToppCell	facs-Kidney-nan-24m\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PABPC1 CD3D CLCA3P ASF1B RHOF	7.46e-05	162	119	5	f223ea00cf7fbc25e6d5a946ee1ff05f7d4abb06
ToppCell	Children_(3_yrs)-Endothelial-endothelial_cell_of_bronchial_vessel\|Children_(3_yrs) / Lineage, Cell type, age group and donor	ANO2 SORBS2 RHOJ ADGRL2 ADGRL3	7.68e-05	163	119	5	977a970b1296234c22178420294cea73506ee02f
ToppCell	367C-Myeloid-Macrophage-FABP4+_Macrophage_3\|Myeloid / Donor, Lineage, Cell class and subclass (all cells)	ANO2 RHOJ LAMA3 NOX4 ADGRL2	8.37e-05	166	119	5	f416d8a322f086c769659a9fab6b460a2d546ab1
ToppCell	Dividing_Macrophages-Cryobiopsy_01\|World / lung cells shred on cell class, cell subclass, sample id	PKD2L1 BRCA2 ASF1B EXO1 UHRF1	8.37e-05	166	119	5	c503036f3c19ef186e1e62c9643c49dea3827f51
ToppCell	Club-club-2\|World / Class top	GARIN5B ANO1 TUBB2A FCGRT DMBT1	8.37e-05	166	119	5	56f11efb6b686b3ee2c34a051f626e3d761b5112
ToppCell	Dividing_Macrophages-Donor_06\|World / lung cells shred on cell class, cell subclass, sample id	PKD2L1 BRCA2 ASF1B EXO1 UHRF1	8.37e-05	166	119	5	ea95b94ccc2ac67df741b30c27f4ae698925875f
ToppCell	343B-Myeloid-Dendritic-cDC_proliferating_2\|Myeloid / Donor, Lineage, Cell class and subclass (all cells)	SRXN1 RHOJ ASF1B EXO1 UHRF1	8.61e-05	167	119	5	3461d14e36f09ddc6ee5549ca4797e16d3f37fcc
ToppCell	Adult-Endothelial-alveolar_capillary_endothelial_cell_(Cap2;_aerocyte)-D231\|Adult / Lineage, Cell type, age group and donor	NOX4 GRM8 FGD5 ADGRL2 ADGRL3	8.61e-05	167	119	5	5af9127bae05768a5164d5708a4ad37edca99324
ToppCell	facs-Large_Intestine-Proximal\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SRXN1 TMPRSS6 FCGRT LRP1 DMBT1	8.86e-05	168	119	5	23e0e1592d7400012d289adb10c7598285bae2e9
ToppCell	343B-Epithelial_cells-Epithelial-J_(AT1-AT2_progenitors)-\|343B / Donor, Lineage, Cell class and subclass (all cells)	LAMA3 BRCA2 ASF1B EXO1 UHRF1	9.11e-05	169	119	5	a949f547b53126a208819bade74a1ac9b2a36ea7
ToppCell	368C-Lymphocytic-NK_cells-NK_cell_E\|368C / Donor, Lineage, Cell class and subclass (all cells)	OFD1 SIRT3 PTPRD PABPC1L GNAI1	9.11e-05	169	119	5	0d96c0b4fd26fbc0bf44ff7bed2936eebcc55b74
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Outer_Medullary_Collecting_Duct_Intercalated_Cell_Type_A\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	PTBP3 FER1L6 ITPR2 PIK3C2G ARHGAP28	9.11e-05	169	119	5	2a21f2cef959526bfe3c8f081f4f7e9dd4e01a37
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	PTBP3 LAMA3 FER1L6 ITPR2 ARHGAP28	9.11e-05	169	119	5	4b3a7b4a497178799b6b2f0b744f5fb752cee31a
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Connecting_Tubule_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	PTBP3 FSTL4 WNK1 GRM8 PIK3C2G	9.11e-05	169	119	5	0332f539a2f7d6dcd081a5d2f567290721f5a329
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Outer_Medullary_Collecting_Duct_Intercalated_Cell_Type_A\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	PTBP3 LAMA3 FER1L6 ITPR2 ARHGAP28	9.11e-05	169	119	5	a4fd646b9bf87225131fca530bd6b52df9eaf489
ToppCell	343B-Epithelial_cells-Epithelial-J_(AT1-AT2_progenitors)\|343B / Donor, Lineage, Cell class and subclass (all cells)	LAMA3 BRCA2 ASF1B EXO1 UHRF1	9.11e-05	169	119	5	195d5cd60d646ac6d40a3321b2f739917e7aef14
ToppCell	facs-Lung-nan-3m-Endothelial-Vein_endothelial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SORBS2 PTPRU SHROOM4 FGD5 ARHGEF26	9.37e-05	170	119	5	8e1f757ed62218c0fb6525f49d142dd2cd29acf9
ToppCell	facs-Lung-nan-3m-Endothelial-vein_endothelial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SORBS2 PTPRU SHROOM4 FGD5 ARHGEF26	9.37e-05	170	119	5	67d7e1da3ebd2d14cb2e67799e94d655027ed5c4
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Endothelial-Endothelial_mature-Endo_capilar-A\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	SORBS2 ZFAT NOX4 PCDHA5 ADGRL2	9.90e-05	172	119	5	c3a99828838af3b85c8c885d69cc8018f55ced50
ToppCell	droplet-Kidney-nan-3m-Epithelial-Pecam____kidney_capillary_endothelial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ANO1 ARHGAP28 FGD5 ARHGEF26 ADGRL3	9.90e-05	172	119	5	073a503dc922e3e3ac3528e249b0f8b74402110b
ToppCell	droplet-Lung-30m-Hematologic-myeloid-myeloid_dendritic_cell-proliferating_dendritic\|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	P3H3 UHRF1 DLG2 EIF2AK4 FBXO21	9.90e-05	172	119	5	b043d4f81dced7fb3326043f68474123be47cc5d
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	PTBP3 FER1L6 ITPR2 PIK3C2G ARHGAP28	1.02e-04	173	119	5	0bc2aacae60c6d3276b0949eb0748b4ac1f56e54
ToppCell	droplet-Mammary_Gland-nan-3m-Endothelial-nan\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ARMC7 ZFAT SGTB MB21D2 FGD5	1.02e-04	173	119	5	fbc8ed566ea36c39c258dd6b3823c82f5d6eb17f
Disease	migraine without aura, susceptibility to, 4	LRP1 FGF6 DLG2	3.28e-05	16	117	3	MONDO_0011847
Disease	pulse pressure measurement	DIP2B EPC2 ZFAT TTC28 ANO1 NOX4 PCDHA5 STEAP2 LACTB CD3D TRANK1 PTPRD MTHFR LRP1 UHRF1 FGD5 EIF2AK4	3.53e-05	1392	117	17	EFO_0005763
Disease	coronary artery disease	PRKD2 SORBS2 PKD2L1 PTPRU SIRT3 CD3D MTHFR LRP1 UHRF1 FGD5 ADGRL2 ARHGEF26 FBXO21 RHOF ADGRL3	7.75e-05	1194	117	15	EFO_0001645
Disease	Attention Deficit Disorder	GRM8 PTPRD ADGRL3	8.86e-05	22	117	3	C0041671
Disease	Minimal Brain Dysfunction	GRM8 PTPRD ADGRL3	8.86e-05	22	117	3	C1321905
Disease	Attention deficit hyperactivity disorder	GRM8 PTPRD ADGRL3	1.16e-04	24	117	3	C1263846
Disease	mean corpuscular hemoglobin concentration	ZFAT EP400 TTC28 TMPRSS6 PABPC4 CGGBP1 TF PABPC1 SIRT3 ITPR2 PTPN6 MTHFR EXO1 EIF2AK4	1.25e-04	1105	117	14	EFO_0004528
Disease	Restless Legs Syndrome	TF PTPRD	1.55e-04	5	117	2	C0035258
Disease	p-tau measurement, cerebrospinal fluid biomarker measurement	TTC28 ADGRL2	1.55e-04	5	117	2	EFO_0004763, EFO_0006794
Disease	red blood cell density measurement	ZFAT EP400 TMPRSS6 CGGBP1 WNK1 TF TMTC3 MTHFR FGD5 EIF2AK4 FBXO21 TASOR	2.00e-04	880	117	12	EFO_0007978
Disease	panic disorder	PTBP3 ANO2 CLU	3.04e-04	33	117	3	EFO_0004262
Disease	Drug toxicity	TF CLU MTHFR ABCC2	3.55e-04	84	117	4	C0013221
Disease	Adverse reaction to drug	TF CLU MTHFR ABCC2	3.55e-04	84	117	4	C0041755
Disease	Colorectal Carcinoma	EPHB6 PTPRU WNK1 TUBB2A PTPRD AKAP9 MTHFR LRP1 EXO1 ABCC2	4.95e-04	702	117	10	C0009402
Disease	Moyamoya disease	FSTL4 MTHFR LRP1	5.39e-04	40	117	3	MONDO_0016820
Disease	maleate measurement, Alpha ketoglutarate measurement, fumarate measurement	RHOJ GRM8	8.38e-04	11	117	2	EFO_0010457, EFO_0010480, EFO_0010509
Disease	insulin sensitivity measurement, response to polyunsaturated fatty acid supplementation	PTPRU ADGRL2	8.38e-04	11	117	2	EFO_0004471, EFO_0009131
Disease	obsolete_red blood cell distribution width	DIP2B EP400 TTC28 TTLL9 TMPRSS6 PABPC4 PKD2L1 WNK1 TF TUBB2A IQGAP1 MTHFR TMLHE EIF2AK4	9.10e-04	1347	117	14	EFO_0005192
Disease	iron biomarker measurement, serum iron measurement	TMPRSS6 TF	1.00e-03	12	117	2	EFO_0004461, EFO_0006332
Disease	Gastrointestinal Diseases	MTHFR ABCC2	1.00e-03	12	117	2	C0017178
Disease	Functional Gastrointestinal Disorders	MTHFR ABCC2	1.00e-03	12	117	2	C0559031
Disease	Cholera Infantum	MTHFR ABCC2	1.00e-03	12	117	2	C1565321
Disease	Modic type vertebral endplate changes	PTPRD DLG2	1.18e-03	13	117	2	HP_0030775
Disease	triacylglycerol 52:2 measurement	ZFAT NOX4 PTPRU	1.37e-03	55	117	3	EFO_0010414
Disease	nephroblastoma (is_implicated_in)	BRCA2 MTHFR	1.38e-03	14	117	2	DOID:2154 (is_implicated_in)
Disease	iron biomarker measurement, transferrin saturation measurement	TMPRSS6 TF	1.38e-03	14	117	2	EFO_0004461, EFO_0006333
Disease	anemia (is_implicated_in)	TF MTHFR	1.38e-03	14	117	2	DOID:2355 (is_implicated_in)
Disease	amino acid measurement	TANC2 PTBP3 ANO2 MED10 CLU DLG2 GNAI1 TNKS2 ADGRL2	1.55e-03	678	117	9	EFO_0005134
Disease	Alopecia, Male Pattern	MTHFR ABCC2	1.58e-03	15	117	2	C4083212
Disease	cleft lip (is_implicated_in)	MTHFR NECTIN1	1.58e-03	15	117	2	DOID:9296 (is_implicated_in)
Disease	Androgenetic Alopecia	MTHFR ABCC2	1.58e-03	15	117	2	C0162311
Disease	Female pattern alopecia (disorder)	MTHFR ABCC2	1.58e-03	15	117	2	C0263477
Disease	atherosclerosis (is_implicated_in)	CLU MTHFR	1.80e-03	16	117	2	DOID:1936 (is_implicated_in)
Disease	transferrin saturation measurement	TMPRSS6 TF	1.80e-03	16	117	2	EFO_0006333
Disease	unipolar depression, response to selective serotonin reuptake inhibitor, mood disorder	FSTL4 GRM8	2.04e-03	17	117	2	EFO_0003761, EFO_0004247, EFO_0005658
Disease	partial epilepsy	PTPRD ADGRL3	2.04e-03	17	117	2	EFO_0004263
Disease	glycine measurement	GRM8 PTPRD MTHFR UNC80	2.20e-03	137	117	4	EFO_0009767
Disease	serum hepcidin measurement	TMPRSS6 TF	2.29e-03	18	117	2	EFO_0004504
Disease	non-alcoholic fatty liver disease (is_implicated_in)	MTHFR ABCC2	2.29e-03	18	117	2	DOID:0080208 (is_implicated_in)
Disease	t-tau:beta-amyloid 1-42 ratio measurement	ZFAT DLG2 ARHGAP28	2.32e-03	66	117	3	EFO_0007708
Disease	blood arsenic measurement	SORBS2 FGD5	2.55e-03	19	117	2	EFO_0021527
Disease	Pseudopelade	MTHFR ABCC2	2.55e-03	19	117	2	C0086873
Disease	Alopecia	MTHFR ABCC2	2.55e-03	19	117	2	C0002170
Disease	aspartate aminotransferase to alanine aminotransferase ratio	DIP2B PKD2L1 FCGRT UHRF1 ABCC2	2.68e-03	239	117	5	EFO_0010934
Disease	Schizophrenia	GRM8 TF NDUFS1 CFAP65 PTPN6 CLU MTHFR LRP1 DLG2 IL3RA	2.74e-03	883	117	10	C0036341
Disease	iron biomarker measurement, transferrin measurement	TMPRSS6 TF	2.83e-03	20	117	2	EFO_0004461, EFO_0006341
Disease	attention deficit hyperactivity disorder (is_implicated_in)	GRM8 MTHFR	2.83e-03	20	117	2	DOID:1094 (is_implicated_in)
Disease	gait measurement	PABPC4 CGGBP1 PTPRD UHRF1	3.05e-03	150	117	4	EFO_0007680
Disease	Antimigraine preparation use measurement	LRP1 FGF6	3.12e-03	21	117	2	EFO_0009939
Disease	chronic myeloid leukemia (is_implicated_in)	MTHFR ABCC2	3.12e-03	21	117	2	DOID:8552 (is_implicated_in)
Disease	Colonic Neoplasms	RHOJ NOX4 MTHFR DMBT1	3.20e-03	152	117	4	C0009375
Disease	cholangiocarcinoma (is_implicated_in)	MTHFR ABCC2	3.42e-03	22	117	2	DOID:4947 (is_implicated_in)
Disease	waist-hip ratio	DMXL2 ZFAT IPO8 TTC28 WNK1 CFAP65 OPTC PTPRD EFR3B DLG2 ARHGEF26 RSBN1L	3.48e-03	1226	117	12	EFO_0004343
Disease	Malignant neoplasm of breast	TMPRSS6 WNK1 PABPC1 PTPRD AKAP9 BRCA2 MTHFR EXO1 UTP20 FGD5 REPS2	3.66e-03	1074	117	11	C0006142
Disease	Malignant tumor of colon	RHOJ NOX4 MTHFR DMBT1	3.75e-03	159	117	4	C0007102
Disease	mean arterial pressure	PABPC4 PKD2L1 PTPRD MTHFR EFR3B FGD5 EIF2AK4	3.81e-03	499	117	7	EFO_0006340

Protein segments in the cluster

Peptide	Gene	Start	Entry
YAPLQAYLRQNDLDI	EP400	411	Q96L91
VPEAESNVNYYNRLY	EPC2	76	Q52LR7
QLQNYDPDRALTDYI	AKAP9	3866	Q99996
DQVYQPLRDRDDAQY	CD3D	146	P04234
QEFPALQERNYSIYL	EIF2AK4	1186	Q9P2K8
ETLLPNNYNAYESDL	FGF6	161	P10767
YQYIAAVDYNPRDNL	ADGRL3	361	Q9HAR2
QYQYIAAVDYNPRDN	ADGRL2	361	O95490
YNVNDYSLRDQLLVE	ARHGEF26	701	Q96DR7
LYRVVPRDQDFQENY	CAPN8	121	A6NHC0
LRRAYLPDGYENENQ	CGGBP1	146	Q9UFW8
YLDEYNPGIFRQVQV	DMXL2	526	Q8TDJ6
NSLIANNIYEAAYPL	ANO2	301	Q9NQ90
YPDANYLDNVLAELA	DTX4	591	Q9Y2E6
AQLPQVYPFAADLYQ	IQGAP1	416	P46940
SAAYYLNDLDRIAQP	GNAI1	151	P63096
LQLIDDQFADAYPQR	OFD1	176	O75665
YVYNNLRPQDTDLEA	PIK3C2G	1136	O75747
YPEDEAAKRALNQYQ	P3H3	346	Q8IVL6
GNYLAAELNPDYRDA	ITPR2	311	Q14571
YVNFQQPADAERALD	PABPC1	56	P11940
ATYPYQVVRARLQDQ	SLC25A32	241	Q9H2D1
AYVNYQQPVDAKRAL	PABPC1L2A	46	Q5JQF8
SQYPLRNEYIGEFVN	RSPH10B	276	P0C881
SQYPLRNEYIGEFVN	RSPH10B2	276	B2RC85
NALPIQVDYDAYDAQ	DEPDC5	451	O75140
QVDYDAYDAQVFRLP	DEPDC5	456	O75140
RYAAQENLEYNVEPQ	FBXO21	561	O94952
YVNFQQPADAERALD	PABPC4	56	Q13310
YFLVNLVDNDFPLDN	MTHFR	616	P42898
DRLPANYLAQEDYAA	MB21D2	341	Q8IYB1
YYDPDVERQQASLNT	LAMA3	366	Q16787
YPDPNYLQNVLAELA	DTX2	596	Q86UW9
EPRALVVDVQNGYLY	LRP1	3146	Q07954
YRLYLEQGSPEAVDN	CFAP65	1026	Q6ZU64
QEENEPVIYNRARFY	LACTB	361	P83111
YPELLVASYNNNEDA	DYNC1I2	291	Q13409
QQYLSYNSLRGEAEP	FCGRT	56	P55899
APLDYEATNFYILNV	FAT2	776	Q9NYQ8
LNPDNYGEVIDLSNY	OPTC	51	Q9UBM4
EENLPVYNRCALYAL	EFR3B	581	Q9Y2G0
YQVLLTDYLNNLCPD	FGD5	1046	Q6ZNL6
SFLADQLDPIYVAYN	DIP2B	1561	Q9P265
AYLAPEVLLNQGYNR	PRKD2	716	Q9BZL6
QFNNYQVRYRPELDL	ABCC2	1301	Q92887
QRYEVDYNLEPFAGL	ANO1	711	Q5XXA6
DPSNYEYLRQLQVLD	ARMC7	46	Q9H6L4
EVFEYIDQGRNPQLY	MED10	66	Q9BTT4
QLRYRLNPNEYFDLD	PCDHA5	166	Q9Y5H7
YINFQQPADAERALD	PABPC1L	56	Q4VXU2
DAPGRYDIFQYQITN	GRM8	466	O00222
TAGQEDYNQLRPLSY	RHOJ	76	Q9H4E5
VRDLDFNPNKQYYLA	EIPR1	231	Q53HC9
ENRPDYVNIQLYLSQ	NOX4	486	Q9NPH5
LGDPNADYINANYID	PTPRU	936	Q92729
YYVNNEYLNPELREN	ASF1B	111	Q9NVP2
ELTYQYRQNIPASEL	CHFR	611	Q96EP1
PADVQYDLYLNVANR	IL3RA	131	P26951
EVEVYDRNSLYNNRP	CD101	641	Q93033
QPERINTADYVGNYL	BRCA2	1701	P51587
FEYRQLEPYELENPN	CRHBP	296	P24387
AVNVRNRYIYVAQPA	FSTL4	506	Q6MZW2
YEALPRQSLYGAQQE	HOXC8	91	P31273
IIAQYQPEDYARFEA	DLG2	496	Q15700
SRPYYVDLNQDLYVQ	DMBT1	2271	Q9UGM3
EAPGEQLYQQSRAYV	C19orf25	56	Q9UFG5
QLPYNEDSYLARFQL	FADS6	321	Q8N9I5
GNTEVPARNLYAYIQ	PTPRD	1616	P23468
EYVAPRVLQQAFNYL	IPO8	316	O15397
NLNADPALNELLVYY	KIF13A	451	Q9H1H9
LVTEGNRNYNYLPFE	FER1L6	561	Q2WGJ9
RIQLYDNDIYFIPRN	RSBN1L	656	Q6PCB5
FLRFINNEYYPADLQ	UTP20	846	O75691
GQEDYDRLRPLSYQN	RHOF	76	Q9HBH0
RQVRYSYLQQDLPDN	TRIM27	336	P14373
DQDRFICIYPAYLNN	SRP19	11	P09132
PNLVRYDDIEGANYF	NDUFS1	651	P28331
PDQTNGNILDYQLRY	EPHB6	511	O15197
RYLPQDQLQDYQHFV	SHROOM4	1441	Q9ULL8
SNLQQYDLPYPEAIF	SIRT3	166	Q9NTG7
RTLPVAQAYQDNLYR	TANC2	1951	Q9HCD6
DLQLERINVYYNEAA	TUBB2A	41	Q13885
RINQYPESNAEYLAS	STEAP2	121	Q8NFT2
VAPYEADAQLAYLNK	EXO1	146	Q9UQ84
FQALYNYTPRNEDEL	SORBS2	1046	O94875
VYLSRYADLLQANPL	TASOR	216	Q9UK61
LQVLDSYRNYAEPLQ	CNBD2	111	Q96M20
DEYNVDQPFYISRRN	CLCA3P	166	Q9Y6N3
RLANLTQGEDQYYLR	CLU	371	P10909
YIPLNNYLVFNDVDG	UBA3	336	Q8TBC4
ADLVPRRGYQEYAIQ	ZFAT	236	Q9P243
PELEQYRLYQAQALY	TTC30B	76	Q8N4P2
EYQLRNYEAAQEALT	TTC30B	261	Q8N4P2
YSDYESNPQLRQAIE	UNC80	2241	Q8N2C7
LDAGLVYDAYLAPNN	TF	81	P02787
VEQLEDYLNFANYLL	TMEM68	31	Q96MH6
EQREYYVNQFRSLQP	REPS2	281	Q8NFH8
NGIDYQLYFPITQDR	MRPS9	296	P82933
PYLEQYQIDCQQFRA	TBC1D8B	831	Q0IIM8
NYNDVAPFEVRLYKN	TNFSF18	106	Q9UNG2
DAYILDVYRINPQAE	ARHGAP28	706	Q9P2N2
RYAAYQQLQRETIPA	SRXN1	101	Q9BYN0
DDRLENVQYPYQLYI	ZBTB44	366	Q8NCP5
YLQYLRSGELPAEQA	USP9Y	1476	O00507
YNAIDNANRILGPAY	PKD2L1	526	Q9P0L9
QALLQYADPVNAHYA	PTBP3	221	O95758
AAGYNNLEVAEYLLQ	TNKS2	686	Q9H2K2
QPYYATRVNAADIEN	PTPN6	211	P29350
QYPEGYLEALANRER	UHRF1	606	Q96T88
YNEALAVDPQNCILY	TTC28	81	Q96AY4
ENYVAQRYIENPYLI	TTLL9	206	Q3SXZ7
PELEQYRLYQAQALY	TTC30A	76	Q86WT1
GTYRTLDPDQLDQQY	SLC46A2	251	Q9BY10
AIELDPNNAVYYCNR	SGTB	111	Q96EQ0
PYSECQNAAQIYRRV	WNK1	421	Q9H4A3
YINEEPLDANGYFNL	TMTC3	661	Q6ZXV5
LENCIDQFYVYRNPE	TRANK1	2366	O15050
GTNLNIDNEDYSRYP	PJA1	86	Q8NG27
IRYNNYDRAVINTVP	TMLHE	331	Q9NVH6
RLYDYLQQLHENPQS	UBQLN3	341	Q9H347
QLIPQDLCSEVYRYQ	TMPRSS6	726	Q8IU80
VSGRQYYLALDAPDN	GARIN5B	126	Q8N5Q1
LGYQYDPEQLDLAEN	NECTIN1	486	Q15223