Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	phosphotransferase activity, alcohol group as acceptor	SMG1 MAK PDK3 INSR HIPK2 ELP1 ALPK1 PFKFB4 PAPSS1 MAP3K1 JAK1 PIK3C2B N4BP2 PI4KB FER MAP3K10 AGK IP6K2	7.81e-06	709	152	18	GO:0016773
GeneOntologyMolecularFunction	kinase activity	SMG1 MAK PDK3 INSR HIPK2 ELP1 ALPK1 PFKFB4 PAPSS1 MAP3K1 JAK1 PIK3C2B N4BP2 PI4KB FER MAP3K10 AGK IP6K2	2.13e-05	764	152	18	GO:0016301
GeneOntologyMolecularFunction	transferase activity, transferring phosphorus-containing groups	SMG1 MAK PDK3 TUT7 INSR HIPK2 ELP1 ALPK1 PFKFB4 PAPSS1 MAP3K1 JAK1 PIK3C2B N4BP2 PI4KB FER MAP3K10 AGK IP6K2	9.57e-05	938	152	19	GO:0016772
HumanPheno	Thenar muscle atrophy	COMP PDK3 SPG11 NEB	1.12e-05	15	51	4	HP:0003393
Domain	NumbF	NUMBL NUMB	6.58e-05	2	152	2	PF06311
Domain	Numb_domain	NUMBL NUMB	6.58e-05	2	152	2	IPR010449
Domain	Numb/numb-like	NUMBL NUMB	6.58e-05	2	152	2	IPR016698
Domain	PI3/4_kinase_CS	SMG1 PIK3C2B PI4KB	2.24e-04	15	152	3	IPR018936
Domain	Cadherin_tail	PCDHGB7 PCDHGB1 PCDHGA11 PCDHAC2	2.26e-04	37	152	4	PF15974
Domain	Cadherin_CBD	PCDHGB7 PCDHGB1 PCDHGA11 PCDHAC2	2.26e-04	37	152	4	IPR031904
Domain	-	SMG1 PIK3C2B PI4KB	2.74e-04	16	152	3	1.10.1070.11
Domain	PI3Kc	SMG1 PIK3C2B PI4KB	2.74e-04	16	152	3	SM00146
Domain	Cadherin_C	PCDHGB7 PCDHGB1 PCDHGA11 PCDHAC2	3.71e-04	42	152	4	IPR032455
Domain	Cadherin_C_2	PCDHGB7 PCDHGB1 PCDHGA11 PCDHAC2	3.71e-04	42	152	4	PF16492
Domain	PI3_PI4_kinase	SMG1 PIK3C2B PI4KB	3.94e-04	18	152	3	PF00454
Domain	PI3_4_KINASE_1	SMG1 PIK3C2B PI4KB	3.94e-04	18	152	3	PS00915
Domain	PI3_4_KINASE_2	SMG1 PIK3C2B PI4KB	3.94e-04	18	152	3	PS00916
Domain	PI3/4_kinase_cat_dom	SMG1 PIK3C2B PI4KB	3.94e-04	18	152	3	IPR000403
Domain	PI3_4_KINASE_3	SMG1 PIK3C2B PI4KB	3.94e-04	18	152	3	PS50290
Domain	ARM-type_fold	SMG1 WAPL ARMC12 MAP3K1 RIF1 PPP2R5D PIK3C2B DIAPH1 TERB1 UNC79	4.68e-04	339	152	10	IPR016024
Domain	TSP_3	COMP THBS2	6.47e-04	5	152	2	PF02412
Domain	TSP3	COMP THBS2	6.47e-04	5	152	2	PS51234
Domain	TSP_CTER	COMP THBS2	6.47e-04	5	152	2	PS51236
Domain	Thrombospondin_3_rpt	COMP THBS2	6.47e-04	5	152	2	IPR017897
Domain	TSP_type-3_rpt	COMP THBS2	6.47e-04	5	152	2	IPR028974
Domain	-	COMP THBS2	6.47e-04	5	152	2	4.10.1080.10
Domain	Thrombospondin_C	COMP THBS2	6.47e-04	5	152	2	IPR008859
Domain	TSP_C	COMP THBS2	6.47e-04	5	152	2	PF05735
Domain	Thrombospondin_3-like_rpt	COMP THBS2	6.47e-04	5	152	2	IPR003367
Domain	FN3	PRTG INSR MDGA2 GHR CNTN5 ASTN2 COL14A1	1.24e-03	199	152	7	PS50853
Pubmed	Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.	NUMBL VWA8 PDK3 RANBP3 SPTBN1 ELP1 SPG11 ECHS1 NSRP1 AKAP12 EFTUD2 PLEKHG1 NIFK THEM4 PPP2R5D PAXBP1 PNPLA6 SACS N4BP2 NUMB COL14A1 DNAJC24 ALAS1 CRYBG3 ZNF512 FAM135A RASAL2 NPAT	1.59e-10	1487	158	28	33957083
Pubmed	Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method.	SLC43A2 USP45 WAPL SPOPL FBXW12 TUT7 SPTBN1 DLGAP5 ZNF507 HIPK2 XIAP UBN2 AKAP12 PAXBP1 ZSCAN10 RESF1 EXOC3L4 DIAPH1 ZNF638 ASXL2 FAM135A PHACTR1 NPAT	8.81e-10	1084	158	23	11544199
Pubmed	A novel gene family NBPF: intricate structure generated by gene duplications during primate evolution.	NBPF8 NBPF12 NBPF11 NBPF1 NBPF10	3.48e-08	21	158	5	16079250
Pubmed	Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.	PRUNE2 CACNA1C NUMBL PCDHGB1 NSD2 INSR HIPK2 XIAP PFKFB4 UBN2 CDC14B NSRP1 NBPF1 PLEKHG4B NADSYN1 THEM4 PNPLA6 NDRG1 GPR158 ZNF638 NUMB ASTN2 ZNF512 GLIS1	7.25e-08	1489	158	24	28611215
Pubmed	Genome-wide CRISPR screens identify novel regulators of wild-type and mutant p53 stability.	KNTC1 ZGRF1 ZNF507 HIPK2 ELP1 DAXX UBN2 KIF20B SETDB1 RESF1 PIK3C2B N4BP2 DIAPH1 CRYBG3 FAM135A	8.81e-08	588	158	15	38580884
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	NUMBL RANBP3 SPTBN1 XIAP ALPK1 PLEKHG1 RESF1 NDRG1 PIK3C2B N4BP2 PI4KB MAP3K10 NUMB NCOA7 CRYBG3 RASAL2 AHNAK2	4.45e-07	861	158	17	36931259
Pubmed	HDLBP Promotes Hepatocellular Carcinoma Proliferation and Sorafenib Resistance by Suppressing Trim71-dependent RAF1 Degradation.	AVEN RC3H2 VWA8 CTSC TUT7 SPTBN1 PPIL4 PCDHAC2 ELP1 ECHS1 FBXO46 MAP3K1 NIFK RIF1 PAXBP1 CLIC1 GCLM TCHHL1 AGK NUMB COL14A1	1.17e-06	1371	158	21	36244648
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	PRUNE2 KNTC1 ALPK1 UBN2 PTGFRN EFTUD2 SHROOM4 SACS N4BP2 ASTN2 ZNF512 FAM135A	2.93e-06	493	158	12	15368895
Pubmed	A BioID-Derived Proximity Interactome for SARS-CoV-2 Proteins.	SMG1 WDR7 BCAS1 PTGFRN AKAP12 JAK1 ARFRP1 PNPLA6 NDRG1 TMF1 NCOA7 FAM135A RASAL2 IGSF3	5.70e-06	719	158	14	35337019
Pubmed	N-Terminal Acetyltransferase Naa40p Whereabouts Put into N-Terminal Proteoform Perspective.	WAPL NUMBL RANBP3 DLGAP5 DVL2 XIAP NSRP1 AKAP12 EFTUD2 RIF1 NDRG1 CLIC1 ZNF638 NUMB NCOA7 AHNAK2	6.06e-06	934	158	16	33916271
Pubmed	Integrating genetic and network analysis to characterize genes related to mouse weight.	VWA8 APOE NEB RIF1	8.91e-06	29	158	4	16934000
Pubmed	Evolutionary history and genome organization of DUF1220 protein domains.	NBPF8 NBPF12 NBPF1	1.08e-05	10	158	3	22973535
Pubmed	mTOR regulates the expression of DNA damage response enzymes in long-lived Snell dwarf, GHRKO, and PAPPA-KO mice.	GHR NDRG1 PAPPA	1.08e-05	10	158	3	27618784
Pubmed	Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.	FAM120B WAPL TUT7 SPTBN1 DLGAP5 PPIL4 ELP1 ATAD2 KIF20B EFTUD2 NIFK RIF1 PNPLA6 CLIC1 DIAPH1 ZNF638 ZNF512 RASAL2 AHNAK2	1.34e-05	1353	158	19	29467282
Pubmed	Why do cellular proteins linked to K63-polyubiquitin chains not associate with proteasomes?	NBPF8 NBPF12 NBPF11 NBPF1 NBPF10 UNC79 RASAL2	1.35e-05	170	158	7	23314748
Pubmed	Defining the proximal interaction networks of Arf GTPases reveals a mechanism for the regulation of PLD1 and PI4KB.	AVEN WDR7 INSR AKAP12 EFTUD2 RIF1 ARFRP1 PI4KB ZNF638 TMF1 PWWP3A FAM135A RASAL2 IGSF3	1.36e-05	777	158	14	35844135
Pubmed	SPOP targets oncogenic protein ZBTB3 for destruction to suppress endometrial cancer.	HIPK2 DAXX SPOP	1.96e-05	12	158	3	31911863
Pubmed	Accelerated failure time models provide a useful statistical framework for aging research.	INSR GHR PAPPA	1.96e-05	12	158	3	19007875
Pubmed	EGFR Signaling Termination via Numb Trafficking in Ependymal Progenitors Controls Postnatal Neurogenic Niche Differentiation.	NUMBL NUMB	2.05e-05	2	158	2	31433979
Pubmed	Shift of Macrophage Phenotype Due to Cartilage Oligomeric Matrix Protein Deficiency Drives Atherosclerotic Calcification.	COMP APOE	2.05e-05	2	158	2	27151399
Pubmed	Tyrosine phosphorylation of the TATA element modulatory factor by the FER nuclear tyrosine kinases.	FER TMF1	2.05e-05	2	158	2	9742951
Pubmed	Normal hemopoiesis and lymphopoiesis in the combined absence of numb and numblike.	NUMBL NUMB	2.05e-05	2	158	2	17513721
Pubmed	Sox9 is increased in arterial plaque and stenosis, associated with synthetic phenotype of vascular smooth muscle cells and causes alterations in extracellular matrix and calcification.	SOX9 APOE	2.05e-05	2	158	2	29777903
Pubmed	Numblike and Numb differentially affect p53 and Sonic Hedgehog signaling.	NUMBL NUMB	2.05e-05	2	158	2	21893032
Pubmed	Variants in NEB and RIF1 genes on chr2q23 are associated with skeletal muscle index in Koreans: genome-wide association study.	NEB RIF1	2.05e-05	2	158	2	33674626
Pubmed	A hedgehog-induced BTB protein modulates hedgehog signaling by degrading Ci/Gli transcription factor.	SPOPL SPOP	2.05e-05	2	158	2	16740475
Pubmed	Evolutionary expansion of SPOP and associated TD/POZ gene family: impact of evolutionary route on gene expression pattern.	SPOPL SPOP	2.05e-05	2	158	2	20399258
Pubmed	Numb and Numblike regulate sarcomere assembly and maintenance.	NUMBL NUMB	2.05e-05	2	158	2	35104799
Pubmed	Gain and loss of function for glutathione synthesis: impact on advanced atherosclerosis in apolipoprotein E-deficient mice.	APOE GCLM	2.05e-05	2	158	2	21868708
Pubmed	Regulation of vascular endothelial growth factor receptor function in angiogenesis by numb and numb-like.	NUMBL NUMB	2.05e-05	2	158	2	26069237
Pubmed	Effect of endothelium-specific insulin resistance on endothelial function in vivo.	INSR APOE	2.05e-05	2	158	2	18835939
Pubmed	Daxx-mediated transcriptional repression of MMP1 gene is reversed by SPOP.	DAXX SPOP	2.05e-05	2	158	2	15240113
Pubmed	HIPK2 regulates transforming growth factor-beta-induced c-Jun NH(2)-terminal kinase activation and apoptosis in human hepatoma cells.	HIPK2 DAXX	2.05e-05	2	158	2	14678985
Pubmed	Depletion of Numb and Numblike in Murine Lung Epithelial Cells Ameliorates Bleomycin-Induced Lung Fibrosis by Inhibiting the β-Catenin Signaling Pathway.	NUMBL NUMB	2.05e-05	2	158	2	34124033
Pubmed	Numb and Numbl act to determine mammary myoepithelial cell fate, maintain epithelial identity, and support lactogenesis.	NUMBL NUMB	2.05e-05	2	158	2	27383182
Pubmed	Cartilage oligomeric matrix protein (COMP) in murine brachiocephalic and carotid atherosclerotic lesions.	COMP APOE	2.05e-05	2	158	2	25133350
Pubmed	Down-regulation of aminolevulinate synthase, the rate-limiting enzyme for heme biosynthesis in Alzheimer's disease.	APOE ALAS1	2.05e-05	2	158	2	19477221
Pubmed	Constitutional translocation t(1;17)(p36.31-p36.13;q11.2-q12.1) in a neuroblastoma patient. Establishment of somatic cell hybrids and identification of PND/A12M2 on chromosome 1 and NF1/SCYA7 on chromosome 17 as breakpoint flanking single copy markers.	NBPF11 NBPF1	2.05e-05	2	158	2	7700633
Pubmed	Transgenic overexpression of pregnancy-associated plasma protein-A in murine arterial smooth muscle accelerates atherosclerotic lesion development.	APOE PAPPA	2.05e-05	2	158	2	20472761
Pubmed	Systemic IL-12 administration alters hepatic dendritic cell stimulation capabilities.	IL12A INSR	2.05e-05	2	158	2	22428016
Pubmed	Potential Prognostic Role for SPOP, DAXX, RARRES1, and LAMP2 as an Autophagy Related Genes in Prostate Cancer.	DAXX SPOP	2.05e-05	2	158	2	30882175
Pubmed	Induction of glutathione biosynthesis by glycine-based treatment mitigates atherosclerosis.	APOE GCLM	2.05e-05	2	158	2	35447412
Pubmed	Variants within the COMP and THBS2 genes are not associated with Achilles tendinopathy in a case-control study of South African and Australian populations.	COMP THBS2	2.05e-05	2	158	2	23875975
Pubmed	Chimeric RNA ASTN2-PAPPAas aggravates tumor progression and metastasis in human esophageal cancer.	PAPPA ASTN2	2.05e-05	2	158	2	33388371
Pubmed	Roadkill attenuates Hedgehog responses through degradation of Cubitus interruptus.	SPOPL SPOP	2.05e-05	2	158	2	16651542
Pubmed	Numb deficiency causes impaired trafficking of mGlu5 in neurons and autistic-like behaviors.	NUMBL NUMB	2.05e-05	2	158	2	31129078
Pubmed	Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.	ZGRF1 ZNF507 DVL2 KIF20B SETDB1 RESF1 N4BP2 TMF1 CRYBG3 NPAT	2.33e-05	418	158	10	34709266
Pubmed	Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.	KNTC1 WAPL NSD2 SPTBN1 PPIL4 ELP1 XIAP IDH2 ATAD2 ECHS1 EFTUD2 NIFK RIF1 PAXBP1 CLIC1 DIAPH1 AGK ZNF512 RASAL2	2.74e-05	1425	158	19	30948266
Pubmed	Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.	NUMBL WDR7 SPTBN1 DLGAP5 DVL2 UBN2 AKAP12 EFTUD2 PPP2R5D GPR158 N4BP2 DIAPH1 UNC79 RASAL2 PHACTR1	3.60e-05	963	158	15	28671696
Pubmed	Scleraxis is required for cell lineage differentiation and extracellular matrix remodeling during murine heart valve formation in vivo.	SOX9 COMP COL14A1	4.02e-05	15	158	3	18802027
Pubmed	The ubiquitin ligase Uhrf2 is a master regulator of cholesterol biosynthesis and is essential for liver regeneration.	NSD2 DVL2 KIF20B RIF1 ZNF638	4.70e-05	86	158	5	37253089
Pubmed	Identification of phagocytosis regulators using magnetic genome-wide CRISPR screens.	NUMBL WDR7 CTSC PAPSS1 NUMB CRYBG3	5.11e-05	143	158	6	30397336
Pubmed	Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.	WAPL VWA8 NSD2 DVL2 XIAP NSRP1 JAK1 NIFK SETDB1 PNPLA6 RESF1 PNMA2 DIAPH1 SPOP SIGLEC1 CRYBG3	5.26e-05	1116	158	16	31753913
Pubmed	Cooperative polarization of MCAM/CD146 and ERM family proteins in melanoma.	NUMBL SPTBN1 CTDSP1 AKAP12 JAK1 NDRG1 NUMB RASAL2 IGSF3	6.10e-05	377	158	9	38117590
Pubmed	Cloning and characterization of the mouse Mcoln1 gene reveals an alternatively spliced transcript not seen in humans.	INSR PNPLA6	6.13e-05	3	158	2	11897010
Pubmed	A CRISPR knockout screen identifies SETDB1-target retroelement silencing factors in embryonic stem cells.	SETDB1 RESF1	6.13e-05	3	158	2	29728365
Pubmed	Fer is a downstream effector of insulin and mediates the activation of signal transducer and activator of transcription 3 in myogenic cells.	JAK1 FER	6.13e-05	3	158	2	12738762
Pubmed	Thrombospondin-1, -2 and -5 have differential effects on vascular smooth muscle cell physiology.	COMP THBS2	6.13e-05	3	158	2	26168731
Pubmed	Cartilage oligomeric matrix protein fine-tunes disturbed flow-induced endothelial activation and atherogenesis.	COMP APOE	6.13e-05	3	158	2	33068727
Pubmed	nSMase2 (Type 2-Neutral Sphingomyelinase) Deficiency or Inhibition by GW4869 Reduces Inflammation and Atherosclerosis in Apoe-/- Mice.	APOE SMPD3	6.13e-05	3	158	2	29794115
Pubmed	Spastic paraplegia proteins spastizin and spatacsin mediate autophagic lysosome reformation.	SPG11 PI4KB	6.13e-05	3	158	2	25365221
Pubmed	BTB domain-containing speckle-type POZ protein (SPOP) serves as an adaptor of Daxx for ubiquitination by Cul3-based ubiquitin ligase.	DAXX SPOP	6.13e-05	3	158	2	16524876
Pubmed	Divergent effects of genetic and pharmacological inhibition of Nox2 NADPH oxidase on insulin resistance-related vascular damage.	INSR APOE	6.13e-05	3	158	2	32401607
Pubmed	Dimerization choices control the ability of axin and dishevelled to activate c-Jun N-terminal kinase/stress-activated protein kinase.	DVL2 MAP3K1	6.13e-05	3	158	2	10829020
Pubmed	Human rhinoviruses induce IL-35-producing Treg via induction of B7-H1 (CD274) and sialoadhesin (CD169) on DC.	IL12A SIGLEC1	6.13e-05	3	158	2	19950173
Pubmed	Myeloid lineage cell-restricted insulin resistance protects apolipoproteinE-deficient mice against atherosclerosis.	INSR APOE	6.13e-05	3	158	2	16581002
Pubmed	A proatherogenic role for cGMP-dependent protein kinase in vascular smooth muscle cells.	CACNA1C APOE	6.13e-05	3	158	2	14597716
Pubmed	The role of interleukin 12 in the development of atherosclerosis in ApoE-deficient mice.	IL12A APOE	6.13e-05	3	158	2	10073981
Pubmed	Accelerated atherosclerosis in Apoe-/- mice heterozygous for the insulin receptor and the insulin receptor substrate-1.	INSR APOE	6.13e-05	3	158	2	22199371
Pubmed	A SOX9-B7x axis safeguards dedifferentiated tumor cells from immune surveillance to drive breast cancer progression.	SOX9 VTCN1	6.13e-05	3	158	2	37963469
Pubmed	Characterization of four mammalian numb protein isoforms. Identification of cytoplasmic and membrane-associated variants of the phosphotyrosine binding domain.	NUMBL NUMB	6.13e-05	3	158	2	10551880
Pubmed	The Notch regulator Numb links the Notch and TCR signaling pathways.	NUMBL NUMB	6.13e-05	3	158	2	15634911
Pubmed	The clathrin adaptor Numb regulates intestinal cholesterol absorption through dynamic interaction with NPC1L1.	NUMBL NUMB	6.13e-05	3	158	2	24336247
Pubmed	Numb regulates the polarized delivery of cyclic nucleotide-gated ion channels in rod photoreceptor cilia.	NUMBL NUMB	6.13e-05	3	158	2	25319694
Pubmed	Numb links extracellular cues to intracellular polarity machinery to promote chemotaxis.	NUMBL NUMB	6.13e-05	3	158	2	21571219
Pubmed	Collagen XII and XIV, new partners of cartilage oligomeric matrix protein in the skin extracellular matrix suprastructure.	COMP COL14A1	6.13e-05	3	158	2	22573329
Pubmed	PHACTR1 modulates vascular compliance but not endothelial function: a translational study.	APOE PHACTR1	6.13e-05	3	158	2	35653516
Pubmed	In vivo analysis of gene expression in long-lived mice lacking the pregnancy-associated plasma protein A (PappA) gene.	GHR PAPPA	6.13e-05	3	158	2	20197085
Pubmed	Genetic deletion of pregnancy-associated plasma protein-A is associated with resistance to atherosclerotic lesion development in apolipoprotein E-deficient mice challenged with a high-fat diet.	APOE PAPPA	6.13e-05	3	158	2	17510462
Pubmed	Analysis of Ku70 S155 Phospho-Specific BioID2 Interactome Identifies Ku Association with TRIP12 in Response to DNA Damage.	WAPL NSD2 SPTBN1 DVL2 RIF1 ZNF638	8.28e-05	156	158	6	37108203
Pubmed	HIV-1 Tat protein induces the production of IDO in human monocyte derived-dendritic cells through a direct mechanism: effect on T cells proliferation.	IL12A JAK1 PIK3C2B	8.45e-05	19	158	3	24073214
Pubmed	Human transcription factor protein interaction networks.	SOX9 SMG1 SPTBN1 ZNF507 PPIL4 HIPK2 FIGN UBN2 NIFK SETDB1 RIF1 RESF1 ZNF638 AGK ASXL2 SPOP ZNF512 NPAT	9.30e-05	1429	158	18	35140242
Pubmed	Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.	NUMBL NSD2 SPTBN1 ELP1 CTDSP1 CDC14B NIFK RIF1 PPP2R5D PNMA2 ZNF638 TMF1 NUMB CRYBG3 ZNF512	9.37e-05	1049	158	15	27880917
Pubmed	Acylglycerol Kinase Mutated in Sengers Syndrome Is a Subunit of the TIM22 Protein Translocase in Mitochondria.	EFTUD2 AGK ALAS1	9.91e-05	20	158	3	28712724
Pubmed	BioID-based intact cell interactome of the Kv1.3 potassium channel identifies a Kv1.3-STAT3-p53 cellular signaling pathway.	NUMBL SPTBN1 DVL2 AKAP12 PPP2R5D NDRG1 GCLM AGK NUMB CRYBG3 FAM135A RASAL2	1.02e-04	708	158	12	39231216
Pubmed	The in vivo Interaction Landscape of Histones H3.1 and H3.3.	SOX9 WAPL NSD2 DLGAP5 DAXX UBN2 ATAD2 KIF20B RIF1 ZNF512 NPAT	1.13e-04	608	158	11	36089195
Pubmed	An organelle-specific protein landscape identifies novel diseases and molecular mechanisms.	MAK NUMBL CCDC150 XIAP IDH2 ECHS1 AKAP12 EFTUD2 SETDB1 RIF1 EFHC1 PPP2R5D PI4KB ZNF638 NUMB COL14A1 RASAL2	1.14e-04	1321	158	17	27173435
Pubmed	A high-throughput approach for measuring temporal changes in the interactome.	PRUNE2 KNTC1 RANBP3 CTSC SPTBN1 DVL2 ELP1 ECHS1 PAPSS1 AKAP12 EFTUD2 PPP2R5D NDRG1 GCLM PNMA2 DIAPH1 NCOA7 AHNAK2	1.16e-04	1455	158	18	22863883
Pubmed	Association studies of low-frequency coding variants in nonsyndromic cleft lip with or without cleft palate.	PRTG N4BP2	1.22e-04	4	158	2	28425186
Pubmed	Tumor suppressor protein Pdcd4 interacts with Daxx and modulates the stability of Daxx and the Hipk2-dependent phosphorylation of p53 at serine 46.	HIPK2 DAXX	1.22e-04	4	158	2	23536002
Pubmed	Endotoxin-tolerant mice have mutations in Toll-like receptor 4 (Tlr4).	PAPPA ASTN2	1.22e-04	4	158	2	9989976
Pubmed	Biologically anchored knowledge expansion approach uncovers KLF4 as a novel insulin signaling regulator.	INSR APOE	1.22e-04	4	158	2	30240435
Pubmed	The role of interleukin-4 and interleukin-12 in the progression of atherosclerosis in apolipoprotein E-deficient mice.	IL12A APOE	1.22e-04	4	158	2	12937153
Pubmed	Differential expression of mammalian Numb, Numblike and Notch1 suggests distinct roles during mouse cortical neurogenesis.	NUMBL NUMB	1.22e-04	4	158	2	9169836
Pubmed	The Lnx family proteins function as molecular scaffolds for Numb family proteins.	NUMBL NUMB	1.22e-04	4	158	2	11922143
Pubmed	The growth hormone receptor associates with Jak1, Jak2 and Tyk2 in human liver.	GHR JAK1	1.22e-04	4	158	2	10502458
Pubmed	Numb-deficient satellite cells have regeneration and proliferation defects.	NUMBL NUMB	1.22e-04	4	158	2	24170859
Pubmed	Numb is required to prevent p53-dependent senescence following skeletal muscle injury.	NUMBL NUMB	1.22e-04	4	158	2	26503169
Pubmed	Protein O-GlcNAcylation Is Essential for the Maintenance of Renal Energy Homeostasis and Function via Lipolysis during Fasting and Diabetes.	APOE NDRG1	1.22e-04	4	158	2	31043434
Pubmed	Stress-dependent Daxx-CHIP interaction suppresses the p53 apoptotic program.	HIPK2 DAXX	1.22e-04	4	158	2	19465479
Cytoband	5q31	PCDHGB7 PCDHGB1 PCDHGA11 PCDHAC2 DIAPH1	5.13e-05	115	158	5	5q31
Cytoband	1q21	NBPF12 SETDB1 THEM4 PI4KB	2.86e-04	91	158	4	1q21
Cytoband	Ensembl 112 genes in cytogenetic band chr1q21	NBPF12 NBPF11 SETDB1 THEM4 TCHHL1 PI4KB NBPF10	5.30e-04	404	158	7	chr1q21
GeneFamily	Neuroblastoma breakpoint family	NBPF8 NBPF12 NBPF11 NBPF1 NBPF10	1.86e-07	23	105	5	662
GeneFamily	Fibronectin type III domain containing	PRTG INSR GHR CNTN5 ASTN2 COL14A1	3.42e-04	160	105	6	555
GeneFamily	Clustered protocadherins	PCDHGB7 PCDHGB1 PCDHGA11 PCDHAC2	5.22e-04	64	105	4	20
GeneFamily	Immunoglobulin like domain containing	VTCN1 MDGA2 PTGFRN CNTN5 IGSF3 PDCD1LG2	9.18e-04	193	105	6	594
Coexpression	HAMAI_APOPTOSIS_VIA_TRAIL_UP	KNTC1 TUT7 DLGAP5 PPIL4 HIPK2 SPG11 ATAD2 NSRP1 KIF20B TDRD7 RIF1 RESF1 SACS FER ZNF638 TMF1	2.42e-06	656	158	16	M18979
Coexpression	HE_LIM_SUN_FETAL_LUNG_C2_PRE_PDC_DC5_CELL	KNTC1 AVEN NSD2 KCNE5 DAXX ATAD2 THEM4 PPP2R5D NDRG1 SACS RAD1 AGK SMPD3 TOP1MT	1.15e-05	578	158	14	M45744
Coexpression	PILON_KLF1_TARGETS_UP	MKRN4P KNTC1 INSR HIPK2 FBXO46 GHR SETDB1 RESF1 GCLM N4BP2 COL14A1 ASXL2 IGSF3	2.60e-05	541	158	13	MM1061
Coexpression	GSE21670_IL6_VS_TGFB_AND_IL6_TREATED_STAT3_KO_CD4_TCELL_DN	RC3H2 SPTBN1 DAXX TDRD7 PAXBP1 NDRG1 HOXD10 PNMA2	2.92e-05	199	158	8	M7451
Coexpression	GSE20366_TREG_VS_NAIVE_CD4_TCELL_HOMEOSTATIC_CONVERSION_UP	AVEN HIPK2 NEB CDC14B NDRG1 N4BP2 IL17RB PDCD1LG2	3.03e-05	200	158	8	M4330
CoexpressionAtlas	DevelopingKidney_e15.5_Cap mesenchyme_emap-27738_k-means-cluster#5_top-relative-expression-ranked_1000	HIPK2 XIAP ATAD2 JMY KIF20B RIF1 NCOA7 ASXL2	1.21e-05	146	155	8	gudmap_developingKidney_e15.5_Cap mesenchyme_1000_k5
ToppCell	COVID-19-kidney-PCT-S2\|kidney / Disease (COVID-19 only), tissue and cell type	PRUNE2 INSR FIGN AKAP12 PAPPA ASTN2 GLIS1 IL17RB	3.93e-07	189	158	8	0be5c669b6b308bd98ddb70c84877c62a6244bbd
ToppCell	droplet-Liver-LIVER_HEP-30m-Endothelial\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PCDHGA11 SPTBN1 AKAP12 PLEKHG1 NDRG1 HOXD10 PIK3C2B RASAL2	4.61e-07	193	158	8	826b8dd801298b3e0cd76232feae5a14026b8806
ToppCell	droplet-Liver-LIVER_HEP-30m-Endothelial-endothelial_cell_of_hepatic_sinusoid\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PCDHGA11 SPTBN1 AKAP12 PLEKHG1 NDRG1 HOXD10 PIK3C2B RASAL2	4.61e-07	193	158	8	87d3a577d37fb0cb4b6313c596310de452bc3872
ToppCell	Control_saline-Endothelial-Endothelial-FOXM1\|Control_saline / Treatment groups by lineage, cell group, cell type	KNTC1 NSD2 ZGRF1 DLGAP5 CCDC150 ATAD2 KIF20B EXOC3L4	6.03e-07	200	158	8	9bbc7b5561151f6ff65f40b3226271def732e5d9
ToppCell	390C-Endothelial_cells-Endothelial-E\|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)	ZGRF1 TUT7 ZNF507 NBPF1 DNAJC24 SMPD3 UNC79	1.86e-06	162	158	7	45be019b50e3727fc9d3fad2ff78e74e4f2d746b
ToppCell	390C-Endothelial_cells-Endothelial-E-\|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)	ZGRF1 TUT7 ZNF507 NBPF1 DNAJC24 SMPD3 UNC79	1.86e-06	162	158	7	fbb0cc2b1434a340dc35058b77c73ea61004c252
ToppCell	PND28-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_T-CD8_T-CD8_T_prolif\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	NSD2 PDK3 DLGAP5 ATAD2 KIF20B IL17RB PDCD1LG2	2.02e-06	164	158	7	5621c2e3fae84d5a2e4f1595e454bcb3a2b3f93c
ToppCell	3'-Distal_airway-Immune_Myeloid-Myeloid_macrophage-alveolar_macrophage-Alveolar_macrophages-Alveolar_macrophages_L.1.0.3.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	SLC43A2 SPG11 PTGFRN PPP2R5D PNPLA6 MAP3K10 ASXL2	3.23e-06	176	158	7	76fdf211bce101e83a27d822cb399487bd107027
ToppCell	COVID-19-kidney-PCT-S2\|COVID-19 / Disease (COVID-19 only), tissue and cell type	PRUNE2 INSR GLYATL1 PAPPA ASTN2 GLIS1 IL17RB	3.74e-06	180	158	7	358923e4228035a3e90e2957392089219e90dcd7
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	PRUNE2 HIPK2 BCAS1 FIGN MAP3K1 CNTN5 ASTN2	4.17e-06	183	158	7	738e94b50c4c08c727d4eed0708dda08aa6891b4
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	PRUNE2 HIPK2 BCAS1 FIGN MAP3K1 CNTN5 ASTN2	4.17e-06	183	158	7	92fbd83a9d13ee91065cbd479fb298f1fd564568
ToppCell	COVID-19-kidney-Mito-rich_PCT\|COVID-19 / Disease (COVID-19 only), tissue and cell type	PRUNE2 INSR GLYATL1 PAPPA ASTN2 GLIS1 IL17RB	4.48e-06	185	158	7	1bbc2ba8a20f72f61981b1301cdd6018cdd9150d
ToppCell	TCGA-Pancreas-Primary_Tumor-Pancreatic_Adenocarcinoma-Ductal_Adenocarcinoma-1\|TCGA-Pancreas / Sample_Type by Project: Shred V9	SMG1 WAPL SPOPL MAP3K1 RESF1 ASXL2 NPAT	4.64e-06	186	158	7	03db813598b67b1e08f759758a1c2023396921fa
ToppCell	COVID-19-kidney-tDL\|kidney / Disease (COVID-19 only), tissue and cell type	PRUNE2 FIGN GLYATL1 PAPPA ASTN2 GLIS1 IL17RB	4.81e-06	187	158	7	d35d27ca3c0e65f92f4508e1cb98a743f44fdcdf
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	KNTC1 NSD2 ZGRF1 DLGAP5 CCDC150 ATAD2 KIF20B	4.81e-06	187	158	7	9351fa87b69a951af85b10bf91fe9b1cce8c0517
ToppCell	COVID-19-kidney-Mito-rich_PCT\|kidney / Disease (COVID-19 only), tissue and cell type	PRUNE2 INSR APOE PAPPA ASTN2 GLIS1 IL17RB	4.81e-06	187	158	7	738ec2611b4be6a08eedad16b57fba84e1f11fef
ToppCell	COVID-19-kidney-Stressed_PCT\|kidney / Disease (COVID-19 only), tissue and cell type	PRUNE2 FIGN GHR GLYATL1 ASTN2 GLIS1 IL17RB	4.81e-06	187	158	7	acd305475f3609800af0d7bc68d83ef41228080b
ToppCell	MatrixFB-Fibroblast-C\|MatrixFB / shred on cell class and cell subclass (v4)	SPTBN1 PTGFRN AKAP12 THBS2 COL14A1 SMPD3 AHNAK2	5.34e-06	190	158	7	d0106f7a21292f0b96ce4337ec3efbb1bd78dd0a
ToppCell	356C-Myeloid-Macrophage-FABP4+_Macrophage_2\|356C / Donor, Lineage, Cell class and subclass (all cells)	APOE PNPLA6 ALAS1 SIGLEC1 IL17RB RASAL2 PDCD1LG2	5.34e-06	190	158	7	4cce4ddb79b7751d0103e10f71156977e0c34439
ToppCell	COVID-19-kidney-VWF+PLVAP+EC\|COVID-19 / Disease (COVID-19 only), tissue and cell type	SPTBN1 INSR HIPK2 AKAP12 PLEKHG1 NCOA7 RASAL2	5.53e-06	191	158	7	2f00d0b7b2ffce8eb3eb5bbae49a0d425b23c982
ToppCell	COVID-19-T_cells-Cycling_NK/T_cells\|COVID-19 / group, cell type (main and fine annotations)	KNTC1 NSD2 ZGRF1 DLGAP5 CCDC150 ATAD2 KIF20B	6.33e-06	195	158	7	764ed100c28d9bc93ee5ecabc5291c8f184d78da
ToppCell	COVID-19-kidney-Fibroblast-2\|COVID-19 / Disease (COVID-19 only), tissue and cell type	CACNA1C FIGN AKAP12 GHR THBS2 HOXD10 PAPPA	6.33e-06	195	158	7	3d62ce1c696f47d4d7eb0c5bb0eec2c24b122bb2
ToppCell	primary_auditory_cortex_(A1C)-Neuronal\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	CACNA1C MDGA2 GPR158 SCN1A UNC79 RASAL2 PHACTR1	6.99e-06	198	158	7	6d18b45eda4014759e6dd282d78ffd28df8a6044
ToppCell	10x3'2.3-week_17-19-Mesenchymal_myocytic-stroma-muscle_stem_cell\|week_17-19 / cell types per 3 fetal stages;per 3',per 5'	SOX9 APOE NEB EDA PTGFRN GHR IGSF3	6.99e-06	198	158	7	55e583321f60c95898d93cd0d2615c6692db52ec
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	PRUNE2 SOX9 CTSC INSR AKAP12 THBS2 IL17RB	6.99e-06	198	158	7	be305d89d48c67ce922fa71aaf15e24d00c89ff6
ToppCell	(04)_Interm._basal>secr.-(2)_GFP_FOXI1\|(04)_Interm._basal>secr. / shred by cell type by condition	INSR HIPK2 XIAP BCAS1 NSRP1 TMF1 NCOA7	7.23e-06	199	158	7	53ca3861f9e00dab3f3fbefb0837857ee39ab084
ToppCell	LPS_anti-TNF-Endothelial-Endothelial-FOXM1\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	KNTC1 NSD2 ZGRF1 DLGAP5 CCDC150 ATAD2 KIF20B	7.23e-06	199	158	7	98575fcce726589e93fbb4df1aab03e57cb56076
ToppCell	LPS_IL1RA-Endothelial-Endothelial-FOXM1\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	KNTC1 NSD2 ZGRF1 DLGAP5 CCDC150 ATAD2 KIF20B	7.23e-06	199	158	7	be2276c9a1994579ba1d2998b49bf549c1324d44
ToppCell	LPS_IL1RA_TNF-Endothelial-Endothelial-FOXM1\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	KNTC1 NSD2 ZGRF1 DLGAP5 CCDC150 ATAD2 KIF20B	7.47e-06	200	158	7	4cfe08878a6981bf7b3567f9e82192d8f060ddde
ToppCell	Parenchymal-NucSeq-Epithelial-Epi_alveolar-Dividing_AT2\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	KNTC1 ZGRF1 DLGAP5 CCDC150 ATAD2 KIF20B PLEKHG4B	7.47e-06	200	158	7	af3dc76b4507bf4edd265169f5dfbbb8a19eb394
ToppCell	E16.5-samps-Mesenchymal-Matrix_fibroblast-_fetal-matrix_-_immature_3\|E16.5-samps / Age Group, Lineage, Cell class and subclass	NR2E3 KCNE5 ASB15 EFTUD2 PNMA2 COL14A1	1.55e-05	149	158	6	651494e84be03dc7b061ebdfa91756a1c507b9b4
ToppCell	367C-Lymphocytic-CD4_T-cell-Treg_cell_1\|CD4_T-cell / Donor, Lineage, Cell class and subclass (all cells)	CTSC BCAS1 FIGN NDRG1 IGSF3 PDCD1LG2	2.23e-05	159	158	6	ae53ab7a1339007d0b245c6c291ac61e5ff5b682
ToppCell	LPS-antiTNF-Endothelial-Mes-Like-Gen_Cap\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	MAK SLCO1B3 UBN2 PIK3C2B GCLM PI4KB	2.85e-05	166	158	6	3b750d4023a0a09d86113aae5a97d84391f7b482
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d03-09-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c03-ITGA4\|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)	SPTBN1 ZNF507 JMY SACS EXOC3L4 ASTN2	2.94e-05	167	158	6	83969c36ac44b96afc9aa09400a99fa2b487f7ff
ToppCell	Control-B_intermediate-1\|Control / disease group and sub_cluster of B and Plasma cells(res = 0.5)	NBPF12 TUT7 ELP1 NBPF11 NBPF1 NBPF10	2.94e-05	167	158	6	948504367ecf58144d9dd74d2ec531358fc4b309
ToppCell	Control-Epithelial_cells-ECM-high_epithelial\|Control / group, cell type (main and fine annotations)	SPTBN1 ZFY PLEKHG1 NCOA7 RASAL2 PHACTR1	3.25e-05	170	158	6	e2023d66e70983c87dacbd6181d3426488d1fc57
ToppCell	severe-Myeloid-Eosinophils\|severe / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs	PAPSS1 AKAP12 PNPLA6 ALAS1 SMPD3 IL17RB	3.25e-05	170	158	6	863f0266d5837cdbc3e09a3fe6a99dd3e6261674
ToppCell	NS-critical-d_0-4-Lymphoid-B_cell\|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	RC3H2 USP45 NSD2 KIF20B PLEKHG1 SACS	3.36e-05	171	158	6	bd1ebd9037a740ad8c01c460d778b0973d8b56df
ToppCell	Control-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_3\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	CACNA1C APOE THBS2 PAPPA COL14A1 GLIS1	3.36e-05	171	158	6	4ede831aed364cb5271f49a8b09bb6d0452f9b35
ToppCell	Control-B_naive-1\|Control / disease group and sub_cluster of B and Plasma cells(res = 0.5)	WAPL TUT7 SPTBN1 NBPF11 NBPF1 NBPF10	3.36e-05	171	158	6	d18855b24aadea38fd1e4592f945cf15b85e05f1
ToppCell	5'-Parenchyma_lung-Immune_Myeloid-Myeloid_macrophage-alveolar_macrophage-Alveolar_macrophages-Alveolar_macrophages_L.1.6.0.0\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CTSC APOE PNPLA6 ALAS1 SIGLEC1 IL17RB	3.47e-05	172	158	6	c8ea80042faf923b08ff03d73100533d521d73ef
ToppCell	facs-Brain_Myeloid-Cerebellum-3m-Myeloid-nan\|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SMG1 CTSC TUT7 MAP3K1 RESF1 NUMB	3.59e-05	173	158	6	869da6a65d1b9b7529c666ec44e3c8ddec2ea408
ToppCell	facs-Brain_Myeloid-Cerebellum-3m-Myeloid\|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SMG1 CTSC TUT7 MAP3K1 RESF1 NUMB	3.59e-05	173	158	6	0672bd8a4a9d18af343d01f09253fb3388896c10
ToppCell	facs-Brain_Myeloid-Cerebellum-3m\|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SMG1 CTSC TUT7 MAP3K1 RESF1 NUMB	3.59e-05	173	158	6	870e091ec30be01a900e1cb8b9ef1880e3b7b50d
ToppCell	facs-Brain_Myeloid-Cerebellum-3m-Myeloid-microglial_cell\|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SMG1 CTSC TUT7 MAP3K1 RESF1 NUMB	3.83e-05	175	158	6	1ea6cf9da26601646f57fa14d558a5e9e1f0b345
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell_cycling-Cycling_Distal_Convoluted_Tubule_Cell_G2M\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	KNTC1 NSD2 ZGRF1 DLGAP5 ATAD2 KIF20B	3.83e-05	175	158	6	876cea684faf42ff3eb4623ad6d7a1fb1276ee02
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	PRUNE2 HIPK2 BCAS1 FIGN MAP3K1 CNTN5	3.95e-05	176	158	6	327a3e81b724252e36d786de92a3ffd721ea6d7b
ToppCell	COVID-19-kidney-PCT-S1/S2\|COVID-19 / Disease (COVID-19 only), tissue and cell type	PRUNE2 GLYATL1 PAPPA ASTN2 GLIS1 IL17RB	4.21e-05	178	158	6	23a12d3d971b857d5be8e907334d1f6b49eeeb32
ToppCell	PND03-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial-Mesothelial_G2M\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	DLGAP5 KIF20B NDRG1 COL14A1 SMPD3 AHNAK2	4.21e-05	178	158	6	c77a1d1a9aef0ab51b4408b9e84f201219788ca2
ToppCell	COVID-19-kidney-Stressed_EC\|COVID-19 / Disease (COVID-19 only), tissue and cell type	SPTBN1 INSR HIPK2 AKAP12 PLEKHG1 NCOA7	4.34e-05	179	158	6	754f69bac7a1d5137f5141f6193285ccbfe361cb
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	PRUNE2 SOX9 FIGN EXOC3L4 GLIS1 IL17RB	4.34e-05	179	158	6	58ae5a97fe2a14e1c6fdeb886397eb06fdaf0428
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell_cycling\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	KNTC1 NSD2 ZGRF1 DLGAP5 ATAD2 KIF20B	4.48e-05	180	158	6	401df9cddcbca1eb8f0d2687bcacd98e95dc1493
ToppCell	COVID-19-kidney-tDL\|COVID-19 / Disease (COVID-19 only), tissue and cell type	PRUNE2 GLYATL1 PAPPA ASTN2 GLIS1 IL17RB	4.48e-05	180	158	6	864c895b5eaedefae86f5829fa344f7b686fb59f
ToppCell	facs-Lung-18m-Endothelial-lymphatic_endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	COMP FIGN THBS2 NDRG1 GLIS1 IGSF3	4.62e-05	181	158	6	b0fff0defba9aea6fba36e378b05a59986e2573a
ToppCell	facs-Lung-18m-Endothelial-lymphatic_endothelial-lymphatic_endothelial_cell\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	COMP FIGN THBS2 NDRG1 GLIS1 IGSF3	4.62e-05	181	158	6	cc77ac0e223e012767222e45c5dcadc246d1aa7c
ToppCell	facs-Lung-18m-Endothelial-lymphatic_endothelial\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	COMP FIGN THBS2 NDRG1 GLIS1 IGSF3	4.62e-05	181	158	6	ecd52f33841f4e9d946a4edad0d58da9b0cc5ffa
ToppCell	Fetal_29-31_weeks-Mesenchymal-myofibroblast_cell-D088\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	CACNA1C NR2E3 HIPK2 CDC14B THBS2 PAPPA	4.76e-05	182	158	6	ed6ae0fd8653f213fe29906a6a4e0729a62e1b75
ToppCell	droplet-Lung-immune-endo-depleted-3m-Myeloid-Proliferating_Alveolar_Macrophage\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PRUNE2 KNTC1 NSD2 DLGAP5 ATAD2 SIGLEC1	4.91e-05	183	158	6	42dc31d587fbb9724b2f0be5ee8ed77233f67b86
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_1\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	VTCN1 HIPK2 BCAS1 MAP3K1 CNTN5 ASTN2	4.91e-05	183	158	6	cfae90c309622b5d499e62a3a8a8b9746478d28d
ToppCell	COVID-19-kidney-PCT-S1\|kidney / Disease (COVID-19 only), tissue and cell type	PRUNE2 FIGN GLYATL1 ASTN2 GLIS1 IL17RB	5.06e-05	184	158	6	51ed1ebfdef45149541917c66cbacad87072e51f
ToppCell	COVID-19-kidney-FLT1+PLVAP+EC\|COVID-19 / Disease (COVID-19 only), tissue and cell type	SPTBN1 INSR HIPK2 AKAP12 PLEKHG1 NDRG1	5.21e-05	185	158	6	673308ca0514a4d3629d61fe91e9d8fb31b72166
ToppCell	Control-T_cells-Cycling_NK/T_cells\|Control / group, cell type (main and fine annotations)	KNTC1 NSD2 DLGAP5 CCDC150 ATAD2 KIF20B	5.21e-05	185	158	6	9766216b41ee62bbac4caa25cb98ec5627a24075
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_G2M\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	NSD2 ZGRF1 DLGAP5 CCDC150 ATAD2 KIF20B	5.21e-05	185	158	6	30e041d6f6e310d64809e9d6d93cd30052972f3b
ToppCell	PCW_05-06-Mesenchymal-Mesenchymal_fibroblastic-mes_immature_adventitial_fibro_(9)\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	CACNA1C MDGA2 APOE CNTN5 COL14A1 GLIS1	5.37e-05	186	158	6	8915436d09775f2828a7678af203b1082b36e21c
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	PRUNE2 INSR FIGN AKAP12 GLIS1 IL17RB	5.37e-05	186	158	6	f28d72b47624b69a580b4429e2be560a26898591
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	PRUNE2 INSR APOE GLYATL1 GLIS1 IL17RB	5.53e-05	187	158	6	1b82920588f9e26ef1db244d452736d75fcfd342
ToppCell	COVID-19-kidney-Fibroblast-1\|COVID-19 / Disease (COVID-19 only), tissue and cell type	CACNA1C INSR AKAP12 GHR THBS2 HOXD10	5.53e-05	187	158	6	76bfe8c42430a230a8bdf299575c444fb7780f24
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	PRUNE2 INSR APOE GLYATL1 GLIS1 IL17RB	5.53e-05	187	158	6	71eb26ebf60cb0848e5bf1cd01edccda621aecd8
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	PRUNE2 FIGN AKAP12 NUMB PAPPA GLIS1	5.53e-05	187	158	6	9d77ca45f7563bd6f2a0c1be5d99d93ad30983f7
ToppCell	COVID-19-kidney\|COVID-19 / Disease (COVID-19 only), tissue and cell type	PRUNE2 NDRG1 PAPPA ASTN2 GLIS1 IL17RB	5.53e-05	187	158	6	d23aae9419d460b78b1d4092d7acd9108a47cfbe
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	PRUNE2 INSR APOE GLYATL1 GLIS1 IL17RB	5.53e-05	187	158	6	c1e4c0345f9bfa0538730bad5ff3fa5240168b25
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell_cycling\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	NSD2 ZGRF1 DLGAP5 VTCN1 ATAD2 KIF20B	5.53e-05	187	158	6	057569c9437219ecc396aa6e673b1178a2273837
ToppCell	cellseq2-Endothelial-Endothelial_Vascular-Endothelial_large_blood_vessel-VEC\|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	USP45 PLEKHG1 PIK3C2B RAD1 PHF13 B4GALT4	5.87e-05	189	158	6	bccb3481ffed597c845fe860da658505316105b5
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	PRUNE2 INSR GLYATL1 PAPPA GLIS1 IL17RB	5.87e-05	189	158	6	204ab61ae606b2d9be0cb6bf6a83a011740693a8
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	PRUNE2 INSR GLYATL1 PAPPA GLIS1 IL17RB	5.87e-05	189	158	6	13fd07cc408a9486f61a7b2c3a132c52d14b438d
ToppCell	Control-Endothelial-Endothelial-FOXM1\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	KNTC1 NSD2 ZGRF1 DLGAP5 CCDC150 KIF20B	5.87e-05	189	158	6	1e1499b062d9c647c8f38b0c4e0d871d159be5dd
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	PRUNE2 INSR FIGN AKAP12 GLIS1 IL17RB	6.04e-05	190	158	6	989d4eefd22d66ecb857836f8fdbcf41e3047f84
ToppCell	LPS_only-Endothelial-Endothelial-Alv_Cap\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	SPTBN1 SLCO1B3 MDGA2 PLEKHG1 PIK3C2B RASAL2	6.04e-05	190	158	6	474cbbab8f3b0a6881fa6c92edb78e43999f9ab0
ToppCell	PCW_10-12-Mesenchymal-Mesenchymal_fibroblastic-mes_adventitial_fibro_(10)\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	CTSC APOE AKAP12 THBS2 PAPPA COL14A1	6.04e-05	190	158	6	4f775ee24b14733f06ae40b45f2dc1a0f0df0705
ToppCell	pdx-Tumor_cells-T1\|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)	KNTC1 NSD2 ZGRF1 DLGAP5 ATAD2 KIF20B	6.04e-05	190	158	6	d06ee5f89f1cec8db6897fe3b2a890a07cd3697b
ToppCell	droplet-Large_Intestine-COLON_PROXIMAL\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	WAPL SPTBN1 XIAP GCLM DIAPH1 TMF1	6.22e-05	191	158	6	60c986d2dcbc19d9338c03da6cb5e1d92fd48f8e
ToppCell	droplet-Lung-18m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l17\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	SOX9 CACNA1C THBS2 PAPPA COL14A1 SMPD3	6.22e-05	191	158	6	b51e0f5d1b93f526160c904e9091313a5364f3a7
ToppCell	facs-Liver-Liver_non-hepato/SCs_st-18m-Endothelial\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SPTBN1 AKAP12 PLEKHG1 PIK3C2B EXOC3L4 RASAL2	6.22e-05	191	158	6	1924af7d8b0a0b892e480a9fd6d874941b0c0b5d
ToppCell	facs-Liver-Liver_non-hepato/SCs_st-18m-Endothelial-endothelial_cell_of_hepatic_sinusoid\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SPTBN1 AKAP12 PLEKHG1 PIK3C2B EXOC3L4 RASAL2	6.22e-05	191	158	6	88f91e57a1409bdeb91e9bf47510a6fb998a1bf5
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Thick_Ascending_Limb_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	VTCN1 BCAS1 MAP3K1 ASTN2 COL14A1 PHACTR1	6.22e-05	191	158	6	5a67ff17fb4b9eff641176dff07830c9cd73754e
ToppCell	PND07-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	AKAP12 THBS2 PAPPA COL14A1 IGSF3 AHNAK2	6.22e-05	191	158	6	9f478f36a0b895e607e3bb77fa0f9f03cc0f33fc
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	VTCN1 BCAS1 MAP3K1 ASTN2 COL14A1 PHACTR1	6.22e-05	191	158	6	55ab2854a02cdcfc395e49870ccb7290b5e5471d
ToppCell	15-Trachea-Epithelial-Submucosal_gland_basal\|Trachea / Age, Tissue, Lineage and Cell class	APOE GHR EXOC3L4 PAPPA COL14A1 IL17RB	6.22e-05	191	158	6	409e12d2bb26b6d2ed025304ca6ace07df16638a
ToppCell	Control-Myeloid-Macrophage_Alveolar\|Myeloid / Disease state, Lineage and Cell class	VWA8 CTSC APOE PNPLA6 ALAS1 RASAL2	6.22e-05	191	158	6	a7bb8aba9c59c037d995a77928cc7b4d5cbb82b9
ToppCell	(1)_Osterolineage_cells-(10)_OLC-1\|(1)_Osterolineage_cells / Cell class and subclass of bone marrow stroma cells in homeostatis	CTSC APOE FIGN RESF1 PAPPA IGSF3	6.22e-05	191	158	6	78ad7c555409ce1391bce406bc0f3ef575329ece
ToppCell	droplet-Large_Intestine-COLON_PROXIMAL-30m-Epithelial\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	WAPL SPTBN1 XIAP GCLM DIAPH1 TMF1	6.22e-05	191	158	6	09db184cb90fe282a14474d7217068c58092c6f8
ToppCell	droplet-Large_Intestine-COLON_PROXIMAL-30m\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	WAPL SPTBN1 XIAP GCLM DIAPH1 TMF1	6.22e-05	191	158	6	973117730d6ba5f127e7a0bfabfd0ff2ca7ac131
ToppCell	COVID-19-kidney-AQP1+PLVAP+EC\|COVID-19 / Disease (COVID-19 only), tissue and cell type	CACNA1C SPTBN1 INSR HIPK2 PLEKHG1 PIK3C2B	6.40e-05	192	158	6	27ff3621e177e7932dd44dd6baa81551ea75a874
ToppCell	PCW_05-06-Mesenchymal-Mesenchymal_fibroblastic-mes_chondroblast_(18)\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	SOX9 CACNA1C PLEKHG1 SCN1A CNTN5 PAPPA	6.40e-05	192	158	6	d0649410cf5eacdb0c1dce70e37c7473ef5fddfa
ToppCell	droplet-Liver-LIVER_HEP-30m-Endothelial-endothelial_cell_of_hepatic_sinusoid\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PCDHGA11 SPTBN1 AKAP12 PLEKHG1 PIK3C2B RASAL2	6.59e-05	193	158	6	d485634c564b268e344b6a2863c26f6adaec9e38
ToppCell	critical-Lymphoid-NK\|Lymphoid / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	PRUNE2 MDGA2 APOE FIGN AKAP12 IGSF3	6.59e-05	193	158	6	6be11fef87af04ee7a3cc223882ccd4077caded9
ToppCell	LAM-LAM-LAM+\|LAM / Condition, Lineage and Cell class	PRUNE2 CACNA1C THBS2 COL14A1 GLIS1 AHNAK2	6.78e-05	194	158	6	4ba73a9145ed44896e359f6df9c1f32bbe24a189
ToppCell	PCW_07-8.5-Mesenchymal-Mesenchymal_fibroblastic-mes_immature_adventitial_fibro_(9)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	CTSC SPTBN1 APOE AKAP12 GHR COL14A1	6.78e-05	194	158	6	5f5f0cdeacd5e1b28717d78dabdb9eb95f661e36
ToppCell	PCW_10-12-Mesenchymal-Mesenchymal_fibroblastic-mes_immature_adventitial_fibro_(9)\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	SPTBN1 APOE FIGN AKAP12 GHR COL14A1	6.78e-05	194	158	6	99577a5a631e607b5abe7a1b0d8d6a5eabe50196
ToppCell	kidney_cells-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	PRUNE2 SOX9 CTSC AKAP12 THBS2 IL17RB	6.78e-05	194	158	6	70185c0b8e0f4e896645b17a243482ba3cdf4a5d
Disease	Keratosis palmoplantaris papulosa	AAGAB COL14A1	2.57e-05	2	150	2	C1835662
Disease	Sarcosine measurement	PCDHGB1 PPP2R5D CNTN5	2.12e-04	23	150	3	EFO_0021668
Disease	white matter integrity, age at assessment	SGTB WDR7 FIGN	3.07e-04	26	150	3	EFO_0004641, EFO_0008007
Disease	axial length measurement, refractive error	CNTN5 ASTN2	3.80e-04	6	150	2	EFO_0005318, MONDO_0004892
Disease	Congenital cataract	TDRD7 AGK	3.80e-04	6	150	2	C0009691
Disease	lung carcinoma (is_implicated_in)	SOX9 APOE	5.30e-04	7	150	2	DOID:3905 (is_implicated_in)
Disease	Common Migraine	ASTN2 PHACTR1	5.30e-04	7	150	2	C0338480
Disease	Swyer Syndrome	SOX9 MAP3K1	5.30e-04	7	150	2	C2936694
Disease	Gonadal Dysgenesis, 46,XY	SOX9 MAP3K1	7.04e-04	8	150	2	C0018054
Disease	Hyperlipoproteinemia	APOE GHR	7.04e-04	8	150	2	cv:C0020476
Disease	breast ductal carcinoma (is_marker_for)	SLCO1B3 XIAP	7.04e-04	8	150	2	DOID:3007 (is_marker_for)
Disease	vitamin D measurement, vitamin D dietary intake measurement	BCAS1 NADSYN1	7.04e-04	8	150	2	EFO_0004631, EFO_0008539
Disease	Mitral valve prolapse	SPTBN1 FBXO46 GLIS1	8.13e-04	36	150	3	HP_0001634
Disease	visceral adipose tissue measurement	KNTC1 CACNA1C MDGA2 DAXX PIK3C2B GPR158 COL14A1 SIGLEC1 UNC79	8.26e-04	481	150	9	EFO_0004765
Disease	pulse pressure measurement, migraine without aura, susceptibility to, 4	SPOP PHACTR1	9.03e-04	9	150	2	EFO_0005763, MONDO_0011847
Disease	Inherited neuropathies	SPG11 PNPLA6 SACS	1.11e-03	40	150	3	C0598589
Disease	Prostatic Neoplasms	BCAS1 MAP3K1 GHR JAK1 SETDB1 NDRG1 TMF1 NCOA7 SPOP B4GALT4	1.26e-03	616	150	10	C0033578
Disease	Malignant neoplasm of prostate	BCAS1 MAP3K1 GHR JAK1 SETDB1 NDRG1 TMF1 NCOA7 SPOP B4GALT4	1.26e-03	616	150	10	C0376358
Disease	Nephrosclerosis	HIPK2 ALPK1	1.37e-03	11	150	2	C0027719
Disease	46,XY partial gonadal dysgenesis	SOX9 MAP3K1	1.37e-03	11	150	2	C4510744
Disease	Myocardial Infarction	APOE GCLM PAPPA PHACTR1	1.43e-03	95	150	4	C0027051
Disease	esophagus squamous cell carcinoma (is_implicated_in)	IDH2 MAP3K1 COL14A1	1.56e-03	45	150	3	DOID:3748 (is_implicated_in)
Disease	Agents acting on the renin-angiotensin system use measurement	CACNA1C INSR HIPK2 APOE FIGN PLEKHG1 PHF13	1.68e-03	335	150	7	EFO_0009931
Disease	malaria	AVEN PDK3 PLEKHG1 ASTN2	1.85e-03	102	150	4	EFO_0001068
Disease	X-24588 measurement	SLCO1B3 NUMB	1.93e-03	13	150	2	EFO_0800898
Disease	overall survival, pancreatic carcinoma	CACNA1C ASTN2 B4GALT4	2.00e-03	49	150	3	EFO_0000638, EFO_0002618
Disease	ocular hypertension, response to triamcinolone acetonide	VWA8 TUT7 KIF20B	2.00e-03	49	150	3	EFO_0006954, EFO_1001069
Disease	Intellectual Disability	SOX9 NSD2 SHROOM4 PPP2R5D SACS SCN1A DIAPH1 PHACTR1	2.11e-03	447	150	8	C3714756
Disease	migraine disorder	MKRN4P FAM47A WAPL HOXD10 PAPPA ASTN2 PHACTR1	2.41e-03	357	150	7	MONDO_0005277
Disease	cardiovascular disease	WAPL INSR HIPK2 APOE FIGN AAGAB PLEKHG1 PHF13	2.42e-03	457	150	8	EFO_0000319
Disease	non-alcoholic fatty liver disease	INSR APOE EXOC3L4 PWWP3A ZNF512	2.43e-03	182	150	5	EFO_0003095
Disease	response to olanzapine	CACNA1C SPOPL	2.58e-03	15	150	2	GO_0097333
Disease	Beta blocking agent use measurement	INSR APOE FIGN PLEKHG1	2.78e-03	114	150	4	EFO_0009929
Disease	Hyperlipoproteinemia Type IIa	APOE GHR	2.94e-03	16	150	2	C0745103
Disease	Keratoderma, Palmoplantar	CTSC AAGAB	2.94e-03	16	150	2	C4551675
Disease	migraine without aura, susceptibility to, 4	ASTN2 PHACTR1	2.94e-03	16	150	2	MONDO_0011847
Disease	Renal Insufficiency	IDH2 APOE	3.32e-03	17	150	2	C1565489
Disease	Malignant neoplasm of breast	NSD2 ELP1 PFKFB4 AKAP12 MAP3K1 RIF1 ARFRP1 NDRG1 CLIC1 N4BP2 ASTN2 DNAJC24 RASAL2	3.39e-03	1074	150	13	C0006142
Disease	brain volume measurement	PRTG SGTB NUMBL NSRP1 PLEKHG1 NCOA7 PAPPA ASTN2 ASXL2	3.50e-03	595	150	9	EFO_0006930
Disease	hypertension, white matter hyperintensity measurement	MAP3K1 PLEKHG1 NUMB	3.91e-03	62	150	3	EFO_0000537, EFO_0005665
Disease	anorectal malformation	ZNF507 THBS2	4.15e-03	19	150	2	MONDO_0019938
Disease	hepatocellular carcinoma (is_marker_for)	INSR SLCO1B3 IDH2 MAP3K1 EFTUD2 SPOP	4.50e-03	301	150	6	DOID:684 (is_marker_for)
Disease	Osteoarthritis of hip	COMP ASTN2	4.59e-03	20	150	2	C0029410
Disease	Calcium channel blocker use measurement	CACNA1C INSR APOE FIGN PLEKHG1	4.75e-03	213	150	5	EFO_0009930
Disease	Antimigraine preparation use measurement	ASTN2 PHACTR1	5.06e-03	21	150	2	EFO_0009939
Disease	Infiltrating duct carcinoma of female breast	SMG1 MAK	5.06e-03	21	150	2	C3165106

Protein segments in the cluster

Peptide	Gene	Start	Entry
EELEKPLVTATCSFQ	EXOC3L4	501	Q17RC7
SKEDFLNICIEPDTI	AGK	326	Q53H12
CQAKVEQAVETEPEP	APOE	16	P02649
TAEEVIKNTEIVPCV	CRYBG3	1791	Q68DQ2
EASTKKVELDNCPSV	B4GALT4	66	O60513
CQEVKVSVAIEDLEP	AKAP12	1521	Q02952
PTDAIVKEFLDICEN	CDC14B	291	O60729
KIDVCPENAEVTLTD	COMP	516	P49747
ECTVSHAVEKINPDE	GCLM	71	P48507
IQESIEASKTALCPE	ASB15	21	Q8WXK1
CVVQFLEKESSLTEP	PPP2R5D	346	Q14738
TSPEETCAQVIREAK	ATAD2	836	Q6PL18
LIAEDDIVSQLPETC	AADACL3	326	Q5VUY0
ENIKPEIVSVTAACE	DIAPH1	951	O60610
KTSVATQCDPEEIIV	DAXX	721	Q9UER7
VVKEEISDDNARLPC	DVL2	66	O14641
NPLASCKTDVLVTED	ASTN2	611	O75129
CKTDVLVTEDPADVR	ASTN2	616	O75129
RIVPVVSQSECKEEA	ASXL2	421	Q76L83
PEEDVQIQACKVIVS	ARMC12	301	Q5T9G4
IIVEFPETNCDVKDR	ALPK1	746	Q96QP1
PTDSDEKKVALNCEV	CNTN5	111	O94779
DKDDEIVFKQPISCV	NIFK	256	Q9BYG3
EEEQTAVETKKQLCP	MKRN4P	236	Q13434
LVDQTIEKVSFCAPD	NUMBL	136	Q9Y6R0
SCINAIDSEPKDVIA	RC3H2	846	Q9HBD1
EVCALEEKEPQKNES	RANBP3	226	Q9H6Z4
SLITAETCAKLEPED	NR2E3	176	Q9Y5X4
KCILQTDVKVEENPD	NSRP1	231	Q9H0G5
LKVPETDEVELTCQA	PDCD1LG2	131	Q9BQ51
VCKINTQEPEETLDF	RAD1	131	O60671
PECVEDSKNLSVAAD	JAK1	761	P23458
ISQESCEKSEPLLIA	PCDHGA11	781	Q9Y5H2
TLKDLESPCQELAVV	GOLGA8S	71	H3BPF8
VLFVCKLNPVTTDED	PPIL4	241	Q8WUA2
CKVIVEVVDENDNSP	PCDHGB7	331	Q9Y5F8
AVPTEQKCDIDITFE	NPAT	431	Q14207
DVPAGTVEECVQKFI	DNAJC24	46	Q6P3W2
ECVVKEVVPGDSVNS	PNPLA6	251	Q8IY17
EDQIVVICATSKPEE	FIGN	621	Q5HY92
VICATSKPEEIDESL	FIGN	626	Q5HY92
PEKDPAVTAEQVCQE	MAP3K10	131	Q02779
PLKTQASEVLVECDS	HIPK2	971	Q9H2X6
ASEVLVECDSLVPVN	HIPK2	976	Q9H2X6
CDSLPSVLQVEEKTE	JMY	721	Q8N9B5
VDIVDNSDCEPKSKL	IP6K2	96	Q9UHH9
PVRVADAAKNTEVCD	ALAS1	531	P13196
IPETVSRQCSKEDKE	GPR158	761	Q5T848
LSTVDLEVKCQPDAA	SLC43A2	296	Q8N370
KLVEAKDEPSQACAE	KCNE5	86	Q9UJ90
DPNITACKKNEETVE	IL17RB	181	Q9NRM6
KICPVETLVEEAIQC	ECHS1	211	P30084
TVTEEIPSCQKLELE	FAM135A	261	Q9P2D6
VDEQEKSIICSVSPK	FBXW12	111	Q6X9E4
KNVKEETVCLTVSPE	FBXO46	386	Q6PJ61
KLECALEFETVAENP	PCDHGB1	96	Q9Y5G3
VDAVVECNSKLDPTK	NDRG1	266	Q92597
PEAKAQDSDKICVVI	CTDSP1	81	Q9GZU7
ESICVDPEVIAANIV	PFKFB4	156	Q16877
EEAAENPKSVREECI	NSD2	381	O96028
EPQKSEEVLKNCEIV	GLYATL1	81	Q969I3
LICNETVEVPKDSKS	KIF20B	811	Q96Q89
CSVLEPVISVRNKEE	RASAL2	316	Q9UJF2
VCKNDPKLSEDSVSV	KNTC1	371	P50748
EDLQREESSIPKTCV	ELP1	306	O95163
TVEACLPLELTKNES	IL12A	81	P29459
SCPKTDSQILKELEE	INSR	711	P06213
PSISVEECLEAFKQV	PNMA2	226	Q9UL42
ECFSEKVPLINELES	PAXBP1	456	Q9Y5B6
EKTDCPELAVENASL	PAPPA	1211	Q13219
DVCTPDNLQKVLESE	SMPD3	561	Q9NY59
ESKVPEDSLEECAIT	NBPF1	196	Q3BBV0
DKAEEVVCAPEDVAS	CRACDL	386	Q6NV74
KISCQVEAVPSEELT	MDGA2	356	Q7Z553
VKAICNALAAVETPE	PIK3C2B	536	O00750
PTVVIECDDNKENVP	PHACTR1	366	Q9C0D0
QDVTVTRKDPVVLDC	PRTG	46	Q2VWP7
VLLCTVQATDPDEKE	PCDHAC2	486	Q9Y5I4
EAPELVLKTDSCDVN	PAPSS1	196	O43252
EVVVDEKPFLQCTRS	EDA	321	Q92838
QDVETCLSIPDIKTA	ARFRP1	136	Q13795
VKCATITPDEARVEE	IDH2	111	P48735
DPLELTCEVASETIQ	IGSF3	161	O75054
VELSDTIQVACLPEK	CTRC	131	Q99895
DCLEDLDSQKVISPI	CCDC150	66	Q8NCX0
PKFIEVTTQELADAC	CACNA1C	2136	Q13936
VDEKCFSVDEIVQPD	GHR	136	P10912
QEEEVCAKPSVTEEK	AVEN	321	Q9NQS1
LADPCVLAKTTEETE	C7orf61	76	Q8IZ16
TSVAVKTCKEDLPQE	FER	586	P16591
EVKFVCQTPAIADIV	COL14A1	146	Q05707
CLAEVSVSSPEVQEK	HOXD10	231	P28358
DECAIESIAVAATPI	CTSC	446	P53634
EEIVPQCLSSEETKN	C1orf112	726	Q9NSG2
VCTKAPEITQDEAEI	C7orf77	6	A4D0Y5
ECAETAVSVIPKEVD	DLGAP5	591	Q15398
PGTSEVDEIFKICQV	MAK	201	P20794
KICESLNVPVDDSLV	EFHC1	601	Q5JVL4
KELLQEDTPSTKECV	FAM47A	581	Q5JRC9
LSDISCVPDVAKEVL	DHRS7C	101	A6NNS2
EKCEQPIDDSLSSIE	CCDC168	3896	Q8NDH2
PDTEADVLTECLVLQ	GLIS1	361	Q8NBF1
AEENVVCESPVEIIK	BCAS1	391	O75363
SDEPKSSCILQITVE	SACS	1751	Q9NZJ4
QEVPICTDPISKQED	FAM120B	506	Q96EK7
IVDQTIEKVSFCAPD	NUMB	106	P49757
TVFTPVEEKCRLDVN	MAP3K1	1111	Q13233
ADDPTELACRVVDTK	PTGFRN	421	Q9P2B2
PEAIICAISAVDEVD	PWWP3A	661	Q2TAK8
EDPSVTCDQVVLVVK	PRUNE2	336	Q8WUY3
VSVPEKDLEKTEECN	PRUNE2	1456	Q8WUY3
NTVVLEPDKCNIAVE	NCOA7	46	Q8NI08
ESKVPEDSLEECAIT	NBPF8	161	Q3BBV2
ESKVPEDSLEECAIT	NBPF10	196	Q6P3W6
ESKVPEDSLEECAIT	NBPF11	196	Q86T75
ESKVPEDSLEECAIT	NBPF12	196	Q5TAG4
DVSIKSPICEKQDES	RIF1	1611	Q5UIP0
KEEPITEVVSQCDLQ	RESF1	1136	Q9HCM1
ERLKQEAVTVPVCED	SMG1	2726	Q96Q15
SQLCDTKEPVEETQE	SHROOM4	611	Q9ULL8
EDKFPVCIREAVSQV	SOX9	66	P48436
SDDPDLVKVVESLTC	TDRD7	586	Q8NHU6
SVIDPEVAQKACQEV	PI4KB	41	Q9UBF8
SIDPTCNVADVVKDA	PDK3	186	Q15120
KEDVPLSCVNEIDTT	SETDB1	686	Q15047
TNTVEELEESRQKCP	SCN1A	721	P35498
SEVPVSLKEAVCEVA	SPTBN1	2251	Q01082
CVVPNKFLVTAEIAE	AAGAB	61	Q6PD74
DPECSVEDSKLSLVL	AHNAK2	4976	Q8IVF2
DTNKIEEFLEAVLCP	CLIC1	76	O00299
QEEPIELKCVSVTGF	SPG11	421	Q96JI7
CATVSPDQVKEIKTE	PHF13	181	Q86YI8
QTVLDKVAEQCEPAE	TMF1	421	P82094
SQPEALSEKEDVCKT	TMF1	436	P82094
AVLECLTFEDVPENK	ZSCAN10	186	Q96SZ4
LVLKDPTDESCVEFS	UBN2	131	Q6ZU65
ITCQTAPEEAFIKLD	TTC30B	366	Q8N4P2
ECANISTVKDPFIDI	USP45	366	Q70EL2
TCVPADINKEEEFVE	XIAP	11	P98170
FSSEEVILKDCSVPN	THEM4	36	Q5T1C6
PDKDAIIQCEVVSSL	PLEKHG4B	301	Q96PX9
PDDKLTLFCEVSVVQ	SPOPL	151	Q6IQ16
PDDKLTLFCEVSVVQ	SPOP	151	O43791
NGTSPEIVEKDCVKE	SLCO1B3	151	Q9NPD5
EDVVINCSRDSKIPE	TOP1MT	216	Q969P6
DTVVSDKCFPLEDTL	WAPL	126	Q7Z5K2
KETTQLIDPDAATCE	SIGLEC1	1686	Q9BZZ2
CKESENSIEDISLPE	TMEM225	181	Q6GV28
ETQELCEIPAKVIQS	ZNF507	81	Q8TCN5
ITCQTAPEEAFIKLD	TTC30A	366	Q86WT1
VVLDECSQITEPASL	ZGRF1	1806	Q86YA3
IQCLETVFKISPEDT	SGTB	36	Q96EQ0
ENDPVAIAECFVSKS	PLEKHG1	181	Q9ULL1
LEAAKTEKQVCEPEN	THBS2	636	P35442
ETQEKECETKDLPVQ	TCHHL1	361	Q5QJ38
IDIKVADPVVTFCET	EFTUD2	651	Q15029
ISLKEENVCEEKNSP	TUT7	926	Q5VYS8
VDEADKAPTNVTCIL	VWA8	846	A3KMH1
ITAVEILNACDEAVP	WDR7	601	Q9Y4E6
NEELVVSASCKEPEQ	ZNF512	531	Q96ME7
TDPFTLCSDIINKEV	TERB1	561	Q8NA31
EKNETVSEILPSTCI	ZNF638	1266	Q14966
CTFEPDIKLSDIVIQ	VTCN1	56	Q7Z7D3
IVSEEVLVADCAPEA	ZFY	171	P08048
TAPLVQVSVEDCSKD	UNC79	1681	Q9P2D8
AALVESPVTQDIICD	NADSYN1	71	Q6IA69
CVLEGDPVKTVVAQE	N4BP2	1561	Q86UW6
ADQLKFTCITDTPEI	NEB	3666	P20929