Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	CTP synthase activity	CTPS2 CTPS1	4.11e-06	2	41	2	GO:0003883
GeneOntologyMolecularFunction	high voltage-gated calcium channel activity	CACNB3 CACNB4	3.69e-04	14	41	2	GO:0008331
GeneOntologyBiologicalProcess	'de novo' CTP biosynthetic process	CTPS2 CTPS1	3.67e-06	2	40	2	GO:0044210
GeneOntologyCellularComponent	cytoophidium	CTPS2 CTPS1	1.12e-05	3	41	2	GO:0097268
Domain	CTP_synthase_N	CTPS2 CTPS1	4.70e-06	2	41	2	IPR017456
Domain	GATase1_CTP_Synthase	CTPS2 CTPS1	4.70e-06	2	41	2	IPR033828
Domain	CTP_synthase	CTPS2 CTPS1	4.70e-06	2	41	2	IPR004468
Domain	CTP_synth_N	CTPS2 CTPS1	4.70e-06	2	41	2	PF06418
Domain	VGCC_beta4Aa_N	CACNB3 CACNB4	2.81e-05	4	41	2	PF12052
Domain	VDCC_L_bsu	CACNB3 CACNB4	2.81e-05	4	41	2	IPR000584
Domain	HJURP_C	MEF2A MEF2C	2.81e-05	4	41	2	IPR022102
Domain	HJURP_C	MEF2A MEF2C	2.81e-05	4	41	2	PF12347
Domain	MADS_MEF2-like	MEF2A MEF2C	2.81e-05	4	41	2	IPR033896
Domain	GATase	CTPS2 CTPS1	4.68e-05	5	41	2	PF00117
Domain	GATASE	CTPS2 CTPS1	7.01e-05	6	41	2	IPR017926
Domain	MADS	MEF2A MEF2C	7.01e-05	6	41	2	SM00432
Domain	MADS_BOX_1	MEF2A MEF2C	7.01e-05	6	41	2	PS00350
Domain	SRF-TF	MEF2A MEF2C	7.01e-05	6	41	2	PF00319
Domain	MADS_BOX_2	MEF2A MEF2C	7.01e-05	6	41	2	PS50066
Domain	GATASE_TYPE_1	CTPS2 CTPS1	7.01e-05	6	41	2	PS51273
Domain	TF_MADSbox	MEF2A MEF2C	9.81e-05	7	41	2	IPR002100
Domain	-	CTPS2 CTPS1	2.09e-04	10	41	2	3.40.50.880
Domain	Class_I_gatase-like	CTPS2 CTPS1	3.06e-04	12	41	2	IPR029062
Domain	Guanylate_kin	CACNB3 CACNB4	1.48e-03	26	41	2	PF00625
Domain	GK/Ca_channel_bsu	CACNB3 CACNB4	1.48e-03	26	41	2	IPR008145
Domain	Guanylate_kin-like_dom	CACNB3 CACNB4	1.48e-03	26	41	2	IPR008144
Domain	GuKc	CACNB3 CACNB4	1.48e-03	26	41	2	SM00072
Domain	-	ZGPAT ZFP36L2	3.48e-03	40	41	2	4.10.1000.10
Domain	ZnF_C3H1	ZGPAT ZFP36L2	4.98e-03	48	41	2	SM00356
Domain	zf-CCCH	ZGPAT ZFP36L2	5.18e-03	49	41	2	PF00642
Domain	Znf_CCCH	ZGPAT ZFP36L2	7.19e-03	58	41	2	IPR000571
Domain	ZF_C3H1	ZGPAT ZFP36L2	7.19e-03	58	41	2	PS50103
Domain	Zinc_finger_PHD-type_CS	KDM7A NSD3	8.96e-03	65	41	2	IPR019786
Domain	PHD	KDM7A NSD3	1.18e-02	75	41	2	PF00628
Pathway	REACTOME_PRESYNAPTIC_DEPOLARIZATION_AND_CALCIUM_CHANNEL_OPENING	CACNB3 CACNB4	2.07e-04	11	28	2	MM14498
Pathway	REACTOME_PRESYNAPTIC_DEPOLARIZATION_AND_CALCIUM_CHANNEL_OPENING	CACNB3 CACNB4	2.07e-04	11	28	2	M26913
Pathway	WP_DRAVET_SYNDROME_SCN1AA1783V_POINT_MUTATION_MODEL	CACNB3 CACNB4 CTPS2	3.98e-04	73	28	3	MM16641
Pathway	WP_SRF_AND_MIRS_IN_SMOOTH_MUSCLE_DIFFERENTIATION_AND_PROLIFERATION	MEF2A MEF2C	5.71e-04	18	28	2	M39393
Pathway	KEGG_MEDICUS_REFERENCE_CARDIAC_TYPE_VGCC_RYR_SIGNALING	CACNB3 CACNB4	7.81e-04	21	28	2	M47950
Pathway	KEGG_MEDICUS_REFERENCE_SKELETAL_TYPE_VGCC_RYR_SIGNALING	CACNB3 CACNB4	7.81e-04	21	28	2	M47949
Pathway	REACTOME_ERK_MAPK_TARGETS	MEF2A MEF2C	8.57e-04	22	28	2	M13408
Pubmed	Critical role for the beta regulatory subunits of Cav channels in T lymphocyte function.	CACNB3 CACNB4	1.36e-06	2	41	2	17028169
Pubmed	Myocyte enhancer factors 2A and 2C induce dilated cardiomyopathy in transgenic mice.	MEF2A MEF2C	1.36e-06	2	41	2	16469744
Pubmed	Restoration of impaired endothelial myocyte enhancer factor 2 function rescues pulmonary arterial hypertension.	MEF2A MEF2C	1.36e-06	2	41	2	25336633
Pubmed	Ba2+ currents in inner and outer hair cells of mice lacking the voltage-dependent Ca2+ channel subunits beta3 or beta4.	CACNB3 CACNB4	1.36e-06	2	41	2	19755851
Pubmed	Overexpression of myocyte enhancer factor 2 and histone hyperacetylation in hepatocellular carcinoma.	MEF2A MEF2C	1.36e-06	2	41	2	17611778
Pubmed	Regulation of myocyte enhancer factor-2 transcription factors by neurotoxins.	MEF2A MEF2C	1.36e-06	2	41	2	21741404
Pubmed	Regulation of human cytidine triphosphate synthetase 2 by phosphorylation.	CTPS2 CTPS1	1.36e-06	2	41	2	20739275
Pubmed	In vivo analysis of MEF2 transcription factors in synapse regulation and neuronal survival.	MEF2A MEF2C	4.06e-06	3	41	2	22496871
Pubmed	Inducible knockout of Mef2a, -c, and -d from nestin-expressing stem/progenitor cells and their progeny unexpectedly uncouples neurogenesis and dendritogenesis in vivo.	MEF2A MEF2C	4.06e-06	3	41	2	26286136
Pubmed	Expression of Human CTP synthetase in Saccharomyces cerevisiae reveals phosphorylation by protein kinase A.	CTPS2 CTPS1	4.06e-06	3	41	2	16179339
Pubmed	The nuclear localization domain of the MEF2 family of transcription factors shows member-specific features and mediates the nuclear import of histone deacetylase 4.	MEF2A MEF2C	4.06e-06	3	41	2	11792813
Pubmed	C5a stimulates the proliferation of breast cancer cells via Akt-dependent RGC-32 gene activation.	C5 RGCC	4.06e-06	3	41	2	25230890
Pubmed	MEF2 transcription factors differentially contribute to retinal ganglion cell loss after optic nerve injury.	MEF2A MEF2C	4.06e-06	3	41	2	33315889
Pubmed	Alternative splicing of the voltage-gated Ca2+ channel beta4 subunit creates a uniquely folded N-terminal protein binding domain with cell-specific expression in the cerebellar cortex.	CACNB3 CACNB4	4.06e-06	3	41	2	16525042
Pubmed	Structural basis of the alpha1-beta subunit interaction of voltage-gated Ca2+ channels.	CACNB3 CACNB4	4.06e-06	3	41	2	15170217
Pubmed	Experience-Dependent and Differential Regulation of Local and Long-Range Excitatory Neocortical Circuits by Postsynaptic Mef2c.	MEF2A MEF2C	4.06e-06	3	41	2	27989458
Pubmed	NANOS1 and PUMILIO2 bind microRNA biogenesis factor GEMIN3, within chromatoid body in human germ cells.	PUM2 DDX20	4.06e-06	3	41	2	21800163
Pubmed	An intragenic MEF2-dependent enhancer directs muscle-specific expression of microRNAs 1 and 133.	MEF2A MEF2C	4.06e-06	3	41	2	18093911
Pubmed	MEF2 is a converging hub for histone deacetylase 4 and phosphatidylinositol 3-kinase/Akt-induced transformation.	MEF2A MEF2C	4.06e-06	3	41	2	24043307
Pubmed	Alternative pre-mRNA splicing governs expression of a conserved acidic transactivation domain in myocyte enhancer factor 2 factors of striated muscle and brain.	MEF2A MEF2C	4.06e-06	3	41	2	15834131
Pubmed	Regional expression and subcellular localization of the voltage-gated calcium channel β subunits in the developing mouse brain.	CACNB3 CACNB4	4.06e-06	3	41	2	22737983
Pubmed	Vgl-4, a novel member of the vestigial-like family of transcription cofactors, regulates alpha1-adrenergic activation of gene expression in cardiac myocytes.	MEF2A MEF2C	8.12e-06	4	41	2	15140898
Pubmed	Neurotoxin-induced selective ubiquitination and regulation of MEF2A isoform in neuronal stress response.	MEF2A MEF2C	8.12e-06	4	41	2	22764880
Pubmed	Transcriptional activity of MEF2 during mouse embryogenesis monitored with a MEF2-dependent transgene.	MEF2A MEF2C	8.12e-06	4	41	2	10207130
Pubmed	Cooperative activation of muscle gene expression by MEF2 and myogenic bHLH proteins.	MEF2A MEF2C	8.12e-06	4	41	2	8548800
Pubmed	Regional chromosomal assignments for four members of the MADS domain transcription enhancer factor 2 (MEF2) gene family to human chromosomes 15q26, 19p12, 5q14, and 1q12-q23.	MEF2A MEF2C	8.12e-06	4	41	2	8575763
Pubmed	Mutations of calcium channel beta subunit genes in mice.	CACNB3 CACNB4	8.12e-06	4	41	2	10494839
Pubmed	Spine growth in the anterior cingulate cortex is necessary for the consolidation of contextual fear memory.	MEF2A MEF2C	8.12e-06	4	41	2	21531906
Pubmed	Targeting of p38 mitogen-activated protein kinases to MEF2 transcription factors.	MEF2A MEF2C	8.12e-06	4	41	2	10330143
Pubmed	Requirement of MEF2A, C, and D for skeletal muscle regeneration.	MEF2A MEF2C	8.12e-06	4	41	2	24591619
Pubmed	Expression of mef2 genes in the mouse central nervous system suggests a role in neuronal maturation.	MEF2A MEF2C	8.12e-06	4	41	2	7643214
Pubmed	Reciprocal interactions regulate targeting of calcium channel beta subunits and membrane expression of alpha1 subunits in cultured hippocampal neurons.	CACNB3 CACNB4	8.12e-06	4	41	2	19996312
Pubmed	TEF-1 and MEF2 transcription factors interact to regulate muscle-specific promoters.	MEF2A MEF2C	8.12e-06	4	41	2	12061776
Pubmed	Neuronal Myocyte-Specific Enhancer Factor 2D (MEF2D) Is Required for Normal Circadian and Sleep Behavior in Mice.	MEF2A MEF2C	8.12e-06	4	41	2	31420455
Pubmed	Early expression of the different isoforms of the myocyte enhancer factor-2 (MEF2) protein in myogenic as well as non-myogenic cell lineages during mouse embryogenesis.	MEF2A MEF2C	8.12e-06	4	41	2	8817457
Pubmed	Dermo-1, a multifunctional basic helix-loop-helix protein, represses MyoD transactivation via the HLH domain, MEF2 interaction, and chromatin deacetylation.	MEF2A MEF2C	8.12e-06	4	41	2	11809751
Pubmed	MEF2 transcription factors regulate distinct gene programs in mammalian skeletal muscle differentiation.	MEF2A MEF2C	8.12e-06	4	41	2	25416778
Pubmed	Proteomic, functional, and domain-based analysis of in vivo 14-3-3 binding proteins involved in cytoskeletal regulation and cellular organization.	ACIN1 RADIL IRS1 CTPS1 PPP1R12A	1.23e-05	255	41	5	15324660
Pubmed	Galpha13 regulates MEF2-dependent gene transcription in endothelial cells: role in angiogenesis.	MEF2A MEF2C	1.35e-05	5	41	2	19093215
Pubmed	Chromosomal localization of the human genes for alpha 1A, alpha 1B, and alpha 1E voltage-dependent Ca2+ channel subunits.	CACNB3 CACNB4	1.35e-05	5	41	2	8825650
Pubmed	Calcineurin initiates skeletal muscle differentiation by activating MEF2 and MyoD.	MEF2A MEF2C	1.35e-05	5	41	2	12694204
Pubmed	Histone demethylase LSD1 is required to induce skeletal muscle differentiation by regulating myogenic factors.	MEF2A MEF2C	1.35e-05	5	41	2	20833138
Pubmed	Expression of MEF2 genes during human cardiac development.	MEF2A MEF2C	1.35e-05	5	41	2	10458488
Pubmed	Absence of MEF2 binding to the A/T-rich element in the muscle creatine kinase (MCK) enhancer correlates with lack of early expression of the MCK gene in embryonic mammalian muscle.	MEF2A MEF2C	1.35e-05	5	41	2	8993831
Pubmed	Diversity and developmental expression of L-type calcium channel beta2 proteins and their influence on calcium current in murine heart.	CACNB3 CACNB4	1.35e-05	5	41	2	19723630
Pubmed	Control of the SOST bone enhancer by PTH using MEF2 transcription factors.	MEF2A MEF2C	1.35e-05	5	41	2	17696759
Pubmed	Postsynaptic FMRP bidirectionally regulates excitatory synapses as a function of developmental age and MEF2 activity.	MEF2A MEF2C	1.35e-05	5	41	2	23511190
Pubmed	Role of the beta(2) subunit of voltage-dependent calcium channels in the retinal outer plexiform layer.	CACNB3 CACNB4	1.35e-05	5	41	2	11980879
Pubmed	Regulatory role of MEF2D in serum induction of the c-jun promoter.	MEF2A MEF2C	1.35e-05	5	41	2	7760790
Pubmed	Cooperative transcriptional activation by the neurogenic basic helix-loop-helix protein MASH1 and members of the myocyte enhancer factor-2 (MEF2) family.	MEF2A MEF2C	1.35e-05	5	41	2	8900141
Pubmed	Regulation of the MEF2 family of transcription factors by p38.	MEF2A MEF2C	1.35e-05	5	41	2	9858528
Pubmed	Membrane hyperpolarization triggers myogenin and myocyte enhancer factor-2 expression during human myoblast differentiation.	MEF2A MEF2C	1.35e-05	5	41	2	15084602
Pubmed	The MEF2B homologue differentially expressed in mouse embryonal carcinoma cells.	MEF2A MEF2C	1.35e-05	5	41	2	7646512
Pubmed	HDAC4 integrates PTH and sympathetic signaling in osteoblasts.	MEF2A MEF2C	1.35e-05	5	41	2	24934156
Pubmed	Interaction of myocyte enhancer factor 2 (MEF2) with a mitogen-activated protein kinase, ERK5/BMK1.	MEF2A MEF2C	1.35e-05	5	41	2	9753748
Pubmed	Cooperation between MEF2 and PPARgamma in human intestinal beta,beta-carotene 15,15'-monooxygenase gene expression.	MEF2A MEF2C	1.35e-05	5	41	2	16504037
Pubmed	MEF2 transcription factors are key regulators of sprouting angiogenesis.	MEF2A MEF2C	1.35e-05	5	41	2	27898394
Pubmed	mTORC1 activity regulates post-translational modifications of glycine decarboxylase to modulate glycine metabolism and tumorigenesis.	KRI1 PUM2 ACIN1 CTPS1 PPP1R12A	1.74e-05	274	41	5	34244482
Pubmed	TRIM72, a novel negative feedback regulator of myogenesis, is transcriptionally activated by the synergism of MyoD (or myogenin) and MEF2.	MEF2A MEF2C	2.03e-05	6	41	2	20399744
Pubmed	Signal-dependent activation of the MEF2 transcription factor by dissociation from histone deacetylases.	MEF2A MEF2C	2.03e-05	6	41	2	10737771
Pubmed	Inactivation of cytidine triphosphate synthase 1 prevents fatal auto-immunity in mice.	CTPS2 CTPS1	2.03e-05	6	41	2	38438357
Pubmed	The nuclear receptor PPARβ/δ programs muscle glucose metabolism in cooperation with AMPK and MEF2.	MEF2A MEF2C	2.03e-05	6	41	2	22135324
Pubmed	The expression of MEF2 genes is implicated in CNS neuronal differentiation.	MEF2A MEF2C	2.03e-05	6	41	2	9013788
Pubmed	Heart of glass anchors Rasip1 at endothelial cell-cell junctions to support vascular integrity.	RADIL HEG1	2.03e-05	6	41	2	26780829
Pubmed	Akt binds prohibitin 2 and relieves its repression of MyoD and muscle differentiation.	MEF2A MEF2C	2.03e-05	6	41	2	15173318
Pubmed	Smad proteins function as co-modulators for MEF2 transcriptional regulatory proteins.	MEF2A MEF2C	2.03e-05	6	41	2	11160896
Pubmed	beta subunit reshuffling modifies N- and P/Q-type Ca2+ channel subunit compositions in lethargic mouse brain.	CACNB3 CACNB4	2.03e-05	6	41	2	10328888
Pubmed	Multiple roles for the MyoD basic region in transmission of transcriptional activation signals and interaction with MEF2.	MEF2A MEF2C	2.84e-05	7	41	2	9418854
Pubmed	Mef2 gene expression marks the cardiac and skeletal muscle lineages during mouse embryogenesis.	MEF2A MEF2C	2.84e-05	7	41	2	8026334
Pubmed	Transcription enhancer factor 1 binds multiple muscle MEF2 and A/T-rich elements during fast-to-slow skeletal muscle fiber type transitions.	MEF2A MEF2C	2.84e-05	7	41	2	12861002
Pubmed	Signal-dependent nuclear export of a histone deacetylase regulates muscle differentiation.	MEF2A MEF2C	2.84e-05	7	41	2	11081517
Pubmed	Histone deacetylase degradation and MEF2 activation promote the formation of slow-twitch myofibers.	MEF2A MEF2C	3.78e-05	8	41	2	17786239
Pubmed	MEF2-dependent recruitment of the HAND1 transcription factor results in synergistic activation of target promoters.	MEF2A MEF2C	3.78e-05	8	41	2	16043483
Pubmed	MEF2B Instructs Germinal Center Development and Acts as an Oncogene in B Cell Lymphomagenesis.	MEF2A MEF2C	3.78e-05	8	41	2	30205047
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	ANKRD11 ZGPAT RADIL IRS1 HEG1 ZFP36L2 REXO1 NSD3	3.81e-05	1105	41	8	35748872
Pubmed	Common alleles in candidate susceptibility genes associated with risk and development of epithelial ovarian cancer.	STAG3 RGCC	4.86e-05	9	41	2	20635389
Pubmed	Response gene to complement 32 is required for C5b-9 induced cell cycle activation in endothelial cells.	C5 RGCC	4.86e-05	9	41	2	19162005
Pubmed	Isolation, characterization, and chromosomal localization of mouse and human COUP-TF I and II genes.	MEF2A MEF2C	4.86e-05	9	41	2	8530078
Pubmed	Functional complementation studies identify candidate genes and common genetic variants associated with ovarian cancer survival.	STAG3 RGCC	4.86e-05	9	41	2	19270026
Pubmed	Combinatorial cis-acting elements control tissue-specific activation of the cardiac troponin I gene in vitro and in vivo.	MEF2A MEF2C	4.86e-05	9	41	2	9738004
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	ANKRD11 NEK4 RADIL IRS1 ZFP36L2 PPP1R12A NSD3	6.00e-05	861	41	7	36931259
Pubmed	CTPS and IMPDH form cytoophidia in developmental thymocytes.	CTPS2 CTPS1	6.07e-05	10	41	2	34022203
Pubmed	Myocyte Enhancer Factor 2c Regulates Dendritic Complexity and Connectivity of Cerebellar Purkinje Cells.	MEF2A MEF2C	6.07e-05	10	41	2	30276662
Pubmed	Control of mouse cardiac morphogenesis and myogenesis by transcription factor MEF2C.	MEF2A MEF2C	7.41e-05	11	41	2	9162005
Pubmed	NCAM induces CaMKIIalpha-mediated RPTPalpha phosphorylation to enhance its catalytic activity and neurite outgrowth.	CACNB3 CACNB4	7.41e-05	11	41	2	18809727
Pubmed	Enhanced Functional Genomic Screening Identifies Novel Mediators of Dual Leucine Zipper Kinase-Dependent Injury Signaling in Neurons.	MEF2A MEF2C	8.88e-05	12	41	2	28641113
Pubmed	Skeletal muscle specification by myogenin and Mef2D via the SWI/SNF ATPase Brg1.	MEF2A MEF2C	8.88e-05	12	41	2	16424906
Pubmed	Coordinated regulation of differentiation and proliferation of embryonic cardiomyocytes by a jumonji (Jarid2)-cyclin D1 pathway.	MEF2A MEF2C	1.05e-04	13	41	2	21447557
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	PUM2 ACIN1 AHCYL2 TENM2 DCAF5	1.13e-04	407	41	5	12693553
Pubmed	A Mef2 gene that generates a muscle-specific isoform via alternative mRNA splicing.	MEF2A MEF2C	1.22e-04	14	41	2	8114702
Pubmed	Cyclin D-cdk4 activity modulates the subnuclear localization and interaction of MEF2 with SRC-family coactivators during skeletal muscle differentiation.	MEF2A MEF2C	1.22e-04	14	41	2	12130539
Pubmed	Genetic mapping of the mouse genes encoding the voltage-sensitive calcium channel subunits.	CACNB3 CACNB4	1.22e-04	14	41	2	7490102
Pubmed	Klf5 regulates muscle differentiation by directly targeting muscle-specific genes in cooperation with MyoD in mice.	KLF13 MEF2C	1.41e-04	15	41	2	27743478
Pubmed	Voltage-activated calcium channel expression profiles in mouse brain and cultured hippocampal neurons.	CACNB3 CACNB4	1.41e-04	15	41	2	20188150
Pubmed	Influence of natriuretic peptide receptor-1 on survival and cardiac hypertrophy during development.	MEF2A MEF2C	1.41e-04	15	41	2	19782130
Pubmed	Differential neuronal targeting of a new and two known calcium channel β4 subunit splice variants correlates with their regulation of gene expression.	CACNB3 CACNB4	1.41e-04	15	41	2	24453333
Pubmed	MEF2C transcription factor controls chondrocyte hypertrophy and bone development.	MEF2A MEF2C	1.82e-04	17	41	2	17336904
Pubmed	MEF2C regulates cortical inhibitory and excitatory synapses and behaviors relevant to neurodevelopmental disorders.	MEF2A MEF2C	1.82e-04	17	41	2	27779093
Pubmed	A deep proteomics perspective on CRM1-mediated nuclear export and nucleocytoplasmic partitioning.	NEK4 AHCYL2 CTPS2 SMG7 ZFP36L2 MEF2A RFWD3	1.91e-04	1038	41	7	26673895
Pubmed	Prediction of the coding sequences of unidentified human genes. XX. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.	ZGPAT RADIL DCAF5	2.77e-04	107	41	3	11347906
Interaction	CACNB2 interactions	NEK4 CACNB3 CACNB4	1.35e-05	23	41	3	int:CACNB2
Cytoband	19p13.2	KRI1 MUC16 YJU2B	1.14e-03	229	41	3	19p13.2
Cytoband	Ensembl 112 genes in cytogenetic band chr19p13	KRI1 MUC16 YJU2B REXO1	5.49e-03	797	41	4	chr19p13
GeneFamily	Myocyte enhancer factor 2 proteins\|MADS box family	MEF2A MEF2C	1.01e-05	4	24	2	649
GeneFamily	Myocyte enhancer factor 2 proteins\|MADS box family	MEF2A MEF2C	1.68e-05	5	24	2	1086
GeneFamily	Calcium voltage-gated channel subunits	CACNB3 CACNB4	5.38e-04	26	24	2	253
GeneFamily	Calcium voltage-gated channel subunits\|Membrane associated guanylate kinases	CACNB3 CACNB4	5.38e-04	26	24	2	904
GeneFamily	PHD finger proteins	KDM7A NSD3	6.30e-03	90	24	2	88
Coexpression	MURARO_PANCREAS_ENDOTHELIAL_CELL	ANKRD11 HEG1 KLF13 ZFP36L2 MEF2A MEF2C RGCC	1.36e-06	362	41	7	M39176
Coexpression	GSE40655_FOXO1_KO_VS_WT_NTREG_UP	KRI1 IRS1 ZFP36L2 MEF2C PPP1R12A	1.47e-05	200	41	5	M9439
Coexpression	GSE13493_CD4INTCD8POS_VS_CD8POS_THYMOCYTE_UP	TACC2 HEG1 MEF2A DCAF5 RGCC	1.47e-05	200	41	5	M3316
Coexpression	GSE43955_TH0_VS_TGFB_IL6_TH17_ACT_CD4_TCELL_4H_DN	CACNB3 IRS1 ZFP36L2 MEF2A REXO1	1.47e-05	200	41	5	M9641
Coexpression	TURJANSKI_MAPK11_TARGETS	MEF2A MEF2C	2.38e-05	5	41	2	M2492
Coexpression	GENTILE_UV_RESPONSE_CLUSTER_D8	IRS1 HEG1 PPP1R12A	2.66e-05	37	41	3	M15693
Coexpression	TURJANSKI_MAPK7_TARGETS	MEF2A MEF2C	4.99e-05	7	41	2	M11218
Coexpression	BUSSLINGER_GASTRIC_IMMUNE_CELLS	ANKRD11 KRI1 PUM2 HEG1 PLXDC1 KLF13 ZFP36L2 DCAF5 PPP1R12A RGCC	7.66e-05	1492	41	10	M40023
Coexpression	TURJANSKI_MAPK14_TARGETS	MEF2A MEF2C	1.07e-04	10	41	2	M14718
Coexpression	GSE21033_3H_VS_24H_POLYIC_STIM_DC_UP	PLXDC1 KLF13 MEF2A NSD3	1.31e-04	166	41	4	M7722
Coexpression	LAKE_ADULT_KIDNEY_C26_MESANGIAL_CELLS	ANKRD11 NKTR MEF2C PPP1R12A	1.67e-04	177	41	4	M39245
Coexpression	GSE3982_EFF_MEMORY_CD4_TCELL_VS_TH2_UP	TRPM8 KDM7A AHCYL2 PLXDC1	2.57e-04	198	41	4	M5580
Coexpression	GSE25088_WT_VS_STAT6_KO_MACROPHAGE_IL4_STIM_UP	KRI1 PLXDC1 STAG3 RGCC	2.62e-04	199	41	4	M8028
Coexpression	GSE32986_UNSTIM_VS_GMCSF_AND_CURDLAN_HIGHDOSE_STIM_DC_DN	NKTR C5 MEF2A RGCC	2.62e-04	199	41	4	M8606
Coexpression	GSE40277_GATA1_AND_SATB1_TRANSDUCED_VS_CTRL_CD4_TCELL_DN	CACNB3 AHCYL2 C5 MEF2A	2.62e-04	199	41	4	M9178
Coexpression	GSE30962_ACUTE_VS_CHRONIC_LCMV_PRIMARY_INF_CD8_TCELL_DN	TACC2 CTPS1 CEP128 MEF2C	2.67e-04	200	41	4	M5048
Coexpression	GSE369_SOCS3_KO_VS_WT_LIVER_DN	MEF2A STAG3 DCAF5 NSD3	2.67e-04	200	41	4	M5963
Coexpression	GSE22601_DOUBLE_POSITIVE_VS_CD8_SINGLE_POSITIVE_THYMOCYTE_UP	AHCYL2 KLF13 PPP1R12A NSD3	2.67e-04	200	41	4	M6253
Coexpression	GSE2585_AIRE_KO_VS_WT_CD80_HIGH_MTEC_UP	NKTR AHCYL2 SMG7 KLF13	2.67e-04	200	41	4	M6266
Coexpression	GSE9988_ANTI_TREM1_VS_CTRL_TREATED_MONOCYTES_DN	PUM2 KLF13 ZFP36L2 DCAF5	2.67e-04	200	41	4	M5851
Coexpression	GSE13229_MATURE_VS_INTMATURE_NKCELL_UP	MUC16 RADIL TACC2 TENM2	2.67e-04	200	41	4	M3213
Coexpression	GSE9988_LOW_LPS_VS_CTRL_TREATED_MONOCYTE_DN	PUM2 KLF13 ZFP36L2 DCAF5	2.67e-04	200	41	4	M5870
Coexpression	GSE29618_PRE_VS_DAY7_FLU_VACCINE_PDC_DN	SMG7 MEF2A PPP1R12A RFWD3	2.67e-04	200	41	4	M4979
Coexpression	GSE43863_TH1_VS_TFH_EFFECTOR_CD4_TCELL_DN	KDM7A CTPS2 KLF13 MEF2A	2.67e-04	200	41	4	M9763
Coexpression	GSE3982_DC_VS_BASOPHIL_UP	ANKRD11 MEF2C RGCC AGBL3	2.67e-04	200	41	4	M5472
Coexpression	STARK_PREFRONTAL_CORTEX_22Q11_DELETION_UP	ANKRD11 ACIN1 SMG7 MEF2C	2.99e-04	206	41	4	M2817
Coexpression	STARK_PREFRONTAL_CORTEX_22Q11_DELETION_UP	ANKRD11 ACIN1 SMG7 MEF2C	3.10e-04	208	41	4	MM581
Coexpression	DACOSTA_UV_RESPONSE_VIA_ERCC3_DN	NEK4 PUM2 IRS1 HEG1 ZFP36L2 MEF2A PPP1R12A	3.30e-04	856	41	7	M4500
Coexpression	MANNO_MIDBRAIN_NEUROTYPES_HENDO	HEG1 KLF13 ZFP36L2 MYCBPAP MEF2A MEF2C RGCC	4.11e-04	888	41	7	M39049
Coexpression	THAKAR_PBMC_INACTIVATED_INFLUENZA_AGE_21_30YO_RESPONDERS_7DY_DN	ANKRD11 NKTR ZFP36L2 YJU2B MEF2A REXO1	4.28e-04	634	41	6	M40866
CoexpressionAtlas	DevelopingGonad_e18.5_ovary_emap-12283_top-relative-expression-ranked_1000	ANKRD11 ACIN1 NKTR HEG1 AHCYL2 PLXDC1 MEF2A STAG3 NSD3	1.39e-05	778	41	9	gudmap_developingGonad_e18.5_ovary_1000
CoexpressionAtlas	DevelopingGonad_e16.5_epididymis_emap-29702_k-means-cluster#2_top-relative-expression-ranked_500	ANKRD11 NKTR HEG1 AHCYL2 NSD3	1.46e-05	162	41	5	gudmap_developingGonad_e16.5_epididymis_500_k2
CoexpressionAtlas	DevelopingGonad_e16.5_ovary_emap-9563_top-relative-expression-ranked_1000	ANKRD11 ACIN1 NKTR HEG1 AHCYL2 PLXDC1 MEF2A STAG3 NSD3	1.65e-05	795	41	9	gudmap_developingGonad_e16.5_ovary_1000
CoexpressionAtlas	DevelopingGonad_e18.5_ovary_emap-12283_k-means-cluster#2_top-relative-expression-ranked_1000	ANKRD11 NKTR HEG1 AHCYL2 NSD3	5.06e-05	210	41	5	gudmap_developingGonad_e18.5_ovary_1000_k2
CoexpressionAtlas	DevelopingGonad_e16.5_ovary_emap-9563_k-means-cluster#2_top-relative-expression-ranked_1000	ANKRD11 NKTR HEG1 AHCYL2 NSD3	7.78e-05	230	41	5	gudmap_developingGonad_e16.5_ovary_1000_k2
CoexpressionAtlas	DevelopingGonad_e14.5_ ovary_emap-6699_top-relative-expression-ranked_1000	ACIN1 NKTR HEG1 AHCYL2 PLXDC1 MEF2A STAG3 NSD3	1.01e-04	776	41	8	gudmap_developingGonad_e14.5_ ovary_1000
CoexpressionAtlas	DevelopingGonad_e16.5_epididymis_emap-29702_top-relative-expression-ranked_1000	ANKRD11 ACIN1 NKTR HEG1 AHCYL2 MEF2A MEF2C NSD3	1.14e-04	790	41	8	gudmap_developingGonad_e16.5_epididymis_1000
CoexpressionAtlas	DevelopingGonad_e16.5_epididymis_emap-29702_top-relative-expression-ranked_500	ANKRD11 ACIN1 NKTR HEG1 AHCYL2 NSD3	1.20e-04	406	41	6	gudmap_developingGonad_e16.5_epididymis_500
CoexpressionAtlas	DevelopingGonad_e18.5_epididymis_emap-13166_top-relative-expression-ranked_1000	ANKRD11 ACIN1 NKTR HEG1 AHCYL2 MEF2A MEF2C NSD3	1.23e-04	799	41	8	gudmap_developingGonad_e18.5_epididymis_1000
CoexpressionAtlas	DevelopingGonad_e12.5_epididymis_emap-29139_top-relative-expression-ranked_1000	ANKRD11 ACIN1 NKTR AHCYL2 PLXDC1 STAG3 MEF2C NSD3	1.31e-04	806	41	8	gudmap_developingGonad_e12.5_epididymis_1000
CoexpressionAtlas	DevelopingGonad_e14.5_ epididymis_emap-29141_k-means-cluster#3_top-relative-expression-ranked_1000	ANKRD11 NKTR HEG1 AHCYL2 NSD3	1.80e-04	275	41	5	gudmap_developingGonad_e14.5_ epididymis_1000_k3
ToppCell	Severe-B_naive-11\|World / disease group and sub_cluster of B and Plasma cells(res = 0.5)	RADIL ZFP36L2 STAG3 MEF2C NSD3	3.72e-07	161	41	5	ad3b58e3a8b59a609c8d2d2690d15218d18eabbd
ToppCell	wk_15-18-Mesenchymal-Myofibro_&_SMC\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	TACC2 IRS1 GUCY1A2 MEF2C PPP1R12A	1.03e-06	198	41	5	c9c96066c7fa897b583657f0b77ea093920ae9ba
ToppCell	LPS_only-Mesenchymal_myocytic-Pericyte\|LPS_only / Treatment groups by lineage, cell group, cell type	GUCY1A2 PLXDC1 TENM2 MEF2C PPP1R12A	1.09e-06	200	41	5	8c8ef2b19ab5b1bfc0fae6c38a330f464f28e86f
ToppCell	LPS_IL1RA-Mesenchymal_myocytic-Pericyte\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	GUCY1A2 PLXDC1 TENM2 MEF2C PPP1R12A	1.09e-06	200	41	5	b22cae282591d8dead9869c2adbb9632615f50f7
ToppCell	LPS_IL1RA-Mesenchymal_myocytic\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	IRS1 GUCY1A2 PLXDC1 TENM2 PPP1R12A	1.09e-06	200	41	5	77631c471cc5d453a749784f838cfa6408caf09b
ToppCell	10x5'-bone_marrow-Lymphocytic_T_CD4-Trm_Th1/Th17\|bone_marrow / Manually curated celltypes from each tissue	TRPM8 PLXDC1 ZFP36L2 RGCC	1.51e-05	163	41	4	4d1fd0b1246833723b938eca0cb246e937380e12
ToppCell	tumor_Lymph_Node_/_Brain-T/NK_cells-CD8+/CD4+_Mixed_Th\|tumor_Lymph_Node_/_Brain / Location, Cell class and cell subclass	PLXDC1 ZFP36L2 STAG3 RGCC	1.67e-05	167	41	4	c0c944eae0514dc8e00d0c2892a0792e157695ec
ToppCell	3'-GW_trimst-1.5-LargeIntestine-Mesenchymal-Pericytes-angiogenic_pericyte\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	GUCY1A2 PLXDC1 MEF2C PPP1R12A	1.87e-05	172	41	4	107417cfab7775bc1f80807115047abfb50b7a7e
ToppCell	droplet-Marrow-nan-3m\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ANKRD11 ZFP36L2 MEF2A MEF2C	2.44e-05	184	41	4	1154a5ad7b8512272b7476f949ddac350910bfb7
ToppCell	facs-Thymus-Flowthrough-3m-Lymphocytic-thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SMG7 PLXDC1 MEF2A RGCC	2.65e-05	188	41	4	59b71462338a7efbacf46577cb07e9db3363afee
ToppCell	droplet-Limb_Muscle-nan-3m-Mesenchymal-unknown\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GUCY1A2 PLXDC1 TENM2 PPP1R12A	2.65e-05	188	41	4	d534ed9870405a3c1075962308f72b460aed17bf
ToppCell	droplet-Limb_Muscle-nan-3m-Endothelial-unknown\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KRI1 CACNB3 PLXDC1 MEF2A	2.71e-05	189	41	4	16a4c92dd7a0d60f3691bd3130a091a9a54730f1
ToppCell	ILEUM-inflamed-(5)_Plasma-(5)_IgA_plasma_cells\|(5)_Plasma / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)	NKTR ZFP36L2 MEF2C NSD3	2.71e-05	189	41	4	a0634d72bfdd5f93877724ed6480b50a3a046f71
ToppCell	tumor_Lymph_Node_/_Brain-Fibroblasts-Pericytes\|Fibroblasts / Location, Cell class and cell subclass	GUCY1A2 PLXDC1 MEF2C PPP1R12A	2.71e-05	189	41	4	f4865b7db16de15120504147a8016ac522ad242a
ToppCell	tumor_Lung-Fibroblasts-Pericytes\|Fibroblasts / Location, Cell class and cell subclass	GUCY1A2 PLXDC1 MEF2C PPP1R12A	2.71e-05	189	41	4	9c407b17d7945e81e1ae6c18452f5d20fb09d563
ToppCell	Primary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_C_(IT_L4_RORB)\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	RADIL TENM2 MEF2A MEF2C	2.76e-05	190	41	4	1bbbf0ce222e51f9fd2daca0c18d3965fd4efd31
ToppCell	3'-GW_trimst-1.5-LargeIntestine-Mesenchymal-Pericytes\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	GUCY1A2 PLXDC1 MEF2C PPP1R12A	2.94e-05	193	41	4	a9349ed5f3c34dcf817b3e84737e5946922ddff3
ToppCell	droplet-Limb_Muscle-MUSCLE\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ANKRD11 MEF2A PPP1R12A NSD3	3.00e-05	194	41	4	e3d63874111d1e8da3977329426e4dcf68d6de87
ToppCell	BL-critical-LOC-Lymphoid-CTL\|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	NKTR KLF13 ZFP36L2 NSD3	3.18e-05	197	41	4	fb70918867fbd111bb192a797dcafed5f39ea299
ToppCell	ILEUM-inflamed-(8)_Fibroblast-(8)_Pericytes\|(8)_Fibroblast / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)	GUCY1A2 PLXDC1 MEF2C PPP1R12A	3.24e-05	198	41	4	5e274c5597d8720290d452465f0bd40637cb3f27
ToppCell	wk_08-11-Mesenchymal-Myofibro_&_SMC-Pericyte\|wk_08-11 / Celltypes from embryonic and fetal-stage human lung	GUCY1A2 PLXDC1 MEF2C PPP1R12A	3.24e-05	198	41	4	72aad5b2dcd8b0bde58828fa4f8129fe6cb6a21d
ToppCell	metastatic_Brain-Fibroblasts-Pericytes\|Fibroblasts / Location, Cell class and cell subclass	GUCY1A2 PLXDC1 MEF2C PPP1R12A	3.24e-05	198	41	4	86a4c8e859ce11a95875f8844963baeb1ba898ec
ToppCell	5'-GW_trimst-2-SmallIntestine-Mesenchymal-Pericytes-angiogenic_pericyte\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	GUCY1A2 PLXDC1 MEF2C PPP1R12A	3.31e-05	199	41	4	9e32644b93fb1c4946dbe388fd5c357304d14e36
ToppCell	(02)_MMP9/10+-(2)_GFP_FOXI1\|(02)_MMP9/10+ / shred by cell type by condition	ANKRD11 IRS1 RGCC NSD3	3.31e-05	199	41	4	18a7f9ced4364f45b184bd529f32ef02c27779d3
ToppCell	Hematolymphoid-Microglia\|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic	CACNB4 ZFP36L2 MEF2A MEF2C	3.37e-05	200	41	4	21bcca3b670fe9bac034aef2275d3de4a9a73e2b
ToppCell	LPS_anti-TNF-Mesenchymal_myocytic\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	IRS1 GUCY1A2 PLXDC1 PPP1R12A	3.37e-05	200	41	4	67dcbd86fbc79fd585d0793f979e4aac100326c9
ToppCell	LPS_IL1RA_TNF-Mesenchymal_myocytic-Pericyte\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	GUCY1A2 PLXDC1 TENM2 MEF2C	3.37e-05	200	41	4	b5b5a32925f225610fe25a021a742d6397162863
ToppCell	Hematolymphoid-Microglia-TYROBP----L1-3\|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic	CACNB4 ZFP36L2 MEF2A MEF2C	3.37e-05	200	41	4	a20dce14f94777687aad57d6fbe3258ad376f63f
ToppCell	Control_saline-Mesenchymal_myocytic-Pericyte\|Control_saline / Treatment groups by lineage, cell group, cell type	GUCY1A2 PLXDC1 TENM2 MEF2C	3.37e-05	200	41	4	cb7ef774b6d300f8019c5b16a04e3ebd165e4f1c
ToppCell	LPS_IL1RA_TNF-Mesenchymal_myocytic\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	IRS1 GUCY1A2 PLXDC1 PPP1R12A	3.37e-05	200	41	4	f599e4b051ac3dad11ad437e98dc8ea6754cca53
ToppCell	LPS_IL1RA-Mesenchymal_myocytic-Pericyte-Pericyte_3\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	TACC2 GUCY1A2 TENM2 MEF2C	3.37e-05	200	41	4	a3a1e35934d676c39f917652e50c502cb2f613c1
ToppCell	Hematolymphoid-Microglia-TYROBP--\|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic	CACNB4 ZFP36L2 MEF2A MEF2C	3.37e-05	200	41	4	dc344b3ec51d506952e38f0b3a7795d65f9dd4eb
ToppCell	Hematolymphoid-Microglia-TYROBP---\|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic	CACNB4 ZFP36L2 MEF2A MEF2C	3.37e-05	200	41	4	a8646d0fca99f10827c2d2a12e584660ef7155f1
ToppCell	Hematolymphoid-Microglia-TYROBP-\|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic	CACNB4 ZFP36L2 MEF2A MEF2C	3.37e-05	200	41	4	3bba5219453322198e8fdb0921d5f8c403598751
ToppCell	Hematolymphoid-Microglia-TYROBP\|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic	CACNB4 ZFP36L2 MEF2A MEF2C	3.37e-05	200	41	4	33036d21c1c82109284473a515c4f890b33fdd5c
ToppCell	LPS_only-Mesenchymal_myocytic\|LPS_only / Treatment groups by lineage, cell group, cell type	TACC2 IRS1 PLXDC1 PPP1R12A	3.37e-05	200	41	4	8bc9923f82bfb836e2f524204c92050edeae8ca5
ToppCell	LPS_only-Mesenchymal_myocytic-Pericyte-Pericyte_3\|LPS_only / Treatment groups by lineage, cell group, cell type	TACC2 GUCY1A2 TENM2 MEF2C	3.37e-05	200	41	4	7c62678cf408aaaf98d6df0fb27814d2007c4521
ToppCell	droplet-Bladder-BLADDER-1m-Epithelial-nan\|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CACNB3 IRS1 PLXDC1	2.88e-04	140	41	3	e442c46979d725ec82f525a001c46d971fcade4d
ToppCell	367C-Lymphocytic-NK_cells-NK_cell_D\|NK_cells / Donor, Lineage, Cell class and subclass (all cells)	SMG7 CEP128 AGBL3	3.39e-04	148	41	3	10dcbdb47cac908648d9d652c8095b536db19b8a
ToppCell	3'_v3-bone_marrow-Lymphocytic_T_CD4-Trm_Th1/Th17\|bone_marrow / Manually curated celltypes from each tissue	RADIL ZFP36L2 RGCC	3.46e-04	149	41	3	264fe2ceac6379b3394d2bb47ef34692e4a64559
ToppCell	356C-Lymphocytic-CD4_T-cell-Treg_cell_4\|356C / Donor, Lineage, Cell class and subclass (all cells)	ZGPAT GOLGA7B NSD3	3.74e-04	153	41	3	cda759ab83a271974651fe4faa21ed4f7ecbb3ae
ToppCell	remission-unassigned\|remission / disease stage, cell group and cell class	CACNB3 TACC2 C5	3.81e-04	154	41	3	4130769829b838cc8a075c87ff6c187f0f507f8b
ToppCell	356C-Lymphocytic-ILC-ILC-3\|356C / Donor, Lineage, Cell class and subclass (all cells)	PLXDC1 ZFP36L2 RGCC	3.81e-04	154	41	3	923f5eb8e9258105dbdbe57a5e7976ef60dae29b
ToppCell	facs-Brain_Non-Myeloid-Hippocampus-24m\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CACNB3 ZFP36L2 GOLGA7B	3.88e-04	155	41	3	72a19a9ecfd13f6769c4b447d3ce01a855ec6ec7
ToppCell	remission-unassigned\|World / disease stage, cell group and cell class	CACNB3 TACC2 C5	3.88e-04	155	41	3	d81bec894381e3e2d6249a567e8108b8423e5c54
ToppCell	10x5'-Liver-Lymphocytic_T_CD4-Tfh\|Liver / Manually curated celltypes from each tissue	CACNB3 CACNB4 AGBL3	3.96e-04	156	41	3	85bc34ff507f9a66c6e3ba7a3ffd5416d0073ccf
ToppCell	droplet-Liver-Npc-21m-Myeloid-myeloid_leukocyte\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CACNB3 PLXDC1 CEP128	4.03e-04	157	41	3	264b22d0ffc43049161843bb55d2eccbf5fca575
ToppCell	droplet-Liver-LIVER_NPC-30m-Myeloid-plasmacytoid_dendritic_cell\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PLXDC1 MEF2C RGCC	4.03e-04	157	41	3	fc127e7720649e746f3d3f5c2e9e63784767106a
ToppCell	droplet-Liver-Npc-21m-Myeloid-macrophage/monocyte\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CACNB3 PLXDC1 CEP128	4.03e-04	157	41	3	67945d37027be62c880d3072afa7ca7e97c76c20
ToppCell	droplet-Liver-LIVER_NPC-30m-Myeloid-plasmacytoid_dendritic_cells\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PLXDC1 MEF2C RGCC	4.03e-04	157	41	3	66a191cef4aa00811bb04462310d012610006f85
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen-high_Fibroblast\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	RADIL GUCY1A2 PLXDC1	4.18e-04	159	41	3	2607b562903228274fbd96168ba826782fab0b53
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen-high_Fibroblast-\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	RADIL GUCY1A2 PLXDC1	4.18e-04	159	41	3	e812cbde59188924c6277c3feadf1a9592fa62a4
ToppCell	TCGA-Adrenal-Primary_Tumor-Pheochromocytoma-Pheochromocytoma-3\|TCGA-Adrenal / Sample_Type by Project: Shred V9	PLXDC1 TENM2 RGCC	4.34e-04	161	41	3	52239a887799362256ecd7e740b716b88ed59a62
ToppCell	BALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_B-Plasma_cell\|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)	IRS1 CEP128 MEF2C	4.42e-04	162	41	3	8278dccdb139396ede34b83b02ebce837f2489d6
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	HEG1 MEF2C RGCC	4.42e-04	162	41	3	c399b9e4854916a59f5cae2d8dbf19660f8759be
ToppCell	normal-na-Lymphocytic_B-B_cell-male\|normal / PBMC cell types (v2) per disease, treatment status, and sex	MUC16 MEF2A MEF2C	4.42e-04	162	41	3	ae292318d339305932457bb0e91430594f7a3dfa
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell_\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	HEG1 MEF2C RGCC	4.42e-04	162	41	3	a291248b693c771845174393934a782f1d8bd7ce
ToppCell	normal_Lymph_Node-B_lymphocytes-Undetermined\|normal_Lymph_Node / Location, Cell class and cell subclass	ZFP36L2 MEF2C NSD3	4.42e-04	162	41	3	91ac35ae7fde411cd6a44e715a33dac62419cab8
ToppCell	3'-GW_trimst-1.5-LargeIntestine-Mesenchymal-Pericytes-Immature_pericyte\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	GUCY1A2 PLXDC1 MEF2C	4.66e-04	165	41	3	3d14f37b8a9c0ddc1130e60a2e08556bad1fb855
ToppCell	LV-13._Vascular_Smooth_Muscle\|World / Chamber and Cluster_Paper	GUCY1A2 MEF2C PPP1R12A	4.66e-04	165	41	3	f37fd95adc95d7753cf6e55ae819976513c7ec77
ToppCell	normal_Lung-T/NK_cells-CD8+/CD4+_Mixed_Th\|normal_Lung / Location, Cell class and cell subclass	SMG7 ZFP36L2 NSD3	4.74e-04	166	41	3	ff32422390852546e0cb216192452e9c47bd9509
ToppCell	droplet-Thymus-nan-24m-Lymphocytic-double_negative_T_cell\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CACNB3 SMG7 REXO1	4.91e-04	168	41	3	de1042267407719f19eb3f580a5df0c9cd0e8273
ToppCell	5'-Adult-LymphNode-Hematopoietic-Plasma_cells-IgG_plasma_cell\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	KLF13 CEP128 MEF2C	4.91e-04	168	41	3	f5a18123f84c62211d9279e9c41e90122e4c4895
ToppCell	normal_Lung-Fibroblasts-Pericytes\|Fibroblasts / Location, Cell class and cell subclass	GUCY1A2 PLXDC1 MEF2C	5.08e-04	170	41	3	d69c0ea4cb6b204f19d0a5d2164afb42184779ac
ToppCell	3'-GW_trimst-1-SmallIntestine-Mesenchymal-Pericytes-angiogenic_pericyte\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	GUCY1A2 PLXDC1 MEF2C	5.08e-04	170	41	3	d9ed257d0938442d0bb280e4c4b0c9b657511b46
ToppCell	Bronchial_Brush-Immune-B_cells\|Immune / Tissue, Lineage and Cell class of Lung Cells from 10X	ZGPAT KLF13 STAG3	5.08e-04	170	41	3	53e9372cb06a2dc5c8ecb3f9af42f3c23da96431
ToppCell	Severe-B_naive-11\|Severe / disease group and sub_cluster of B and Plasma cells(res = 0.5)	ZFP36L2 MEF2C NSD3	5.17e-04	171	41	3	7c2699f19ca38414447a286f7658f507882d57c2
ToppCell	facs\|World / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HEG1 KLF13 NSD3	5.17e-04	171	41	3	c9990bc041a632b2f7bbebbfe737772c423d7027
ToppCell	5'-GW_trimst-1.5-LargeIntestine-Mesenchymal-Pericytes-angiogenic_pericyte\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	GUCY1A2 PLXDC1 MEF2C	5.17e-04	171	41	3	285533ca2a6a411773313166bee35542f34d1a3c
ToppCell	3'_v3-lymph-node_spleen\|World / Manually curated celltypes from each tissue	NKTR KLF13 ZFP36L2	5.17e-04	171	41	3	7aae88da5b37c20f10118325a048f08906be994c
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-kidney_interstitial_fibroblast_5\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	RADIL GUCY1A2 PLXDC1	5.17e-04	171	41	3	2a34685f7d83d1cf9a88d304173cbca868c5f9fd
ToppCell	droplet-Liver-LIVER-30m-Myeloid-plasmacytoid_dendritic_cell\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CEP128 MEF2C RGCC	5.26e-04	172	41	3	24ecfda5e43e28f190089770cd2eae5bf2ed292b
ToppCell	droplet-Liver-LIVER-30m-Myeloid-plasmacytoid_dendritic_cells\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CEP128 MEF2C RGCC	5.26e-04	172	41	3	db5a31cafce4346fe459d7f35210823fd7004439
ToppCell	facs-Brain_Myeloid-Cerebellum-3m-Myeloid-nan\|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KDM7A ZFP36L2 MEF2A	5.35e-04	173	41	3	869da6a65d1b9b7529c666ec44e3c8ddec2ea408
ToppCell	droplet-Thymus-nan-18m-Lymphocytic-DN3_thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	AHCYL2 ZFP36L2 RGCC	5.35e-04	173	41	3	5d7c53c6d1cdd385e44b79b82faec901747d1736
ToppCell	droplet-Lung-nan-21m-Myeloid-Plasmacytoid_Dendritic\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PLXDC1 CEP128 MEF2C	5.35e-04	173	41	3	8fb32a9f2dbec16de840d55b4db7e7718f5a2a7a
ToppCell	facs-Brain_Myeloid-Cerebellum-3m-Myeloid\|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KDM7A ZFP36L2 MEF2A	5.35e-04	173	41	3	0672bd8a4a9d18af343d01f09253fb3388896c10
ToppCell	droplet-Lung-nan-21m-Myeloid-plasmacytoid_dendritic_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PLXDC1 CEP128 MEF2C	5.35e-04	173	41	3	f663571aaae2365660a8b526c355f4bd1a124a74
ToppCell	3'-Adult-SmallIntestine-Endothelial-blood_vessel_EC-Mature_venous_EC\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	TRPM8 HEG1 MEF2C	5.35e-04	173	41	3	b57d14e2c2368304cb903562d06ce8228f53857c
ToppCell	facs-Brain_Myeloid-Cerebellum-3m\|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KDM7A ZFP36L2 MEF2A	5.35e-04	173	41	3	870e091ec30be01a900e1cb8b9ef1880e3b7b50d
ToppCell	droplet-Thymus-nan-18m-Lymphocytic-Double_negative_thymocyte,_DN3_(Cd8-,_Cd4-),_some_express_pre_TCR_alpha\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	AHCYL2 ZFP36L2 RGCC	5.44e-04	174	41	3	9eab43885496b8586f8ec5b4bcb1fd5b209218e5
ToppCell	facs-Trachea-18m-Mesenchymal-fibroblast-fibroblast_of_trachea-tracheal_fibroblast_l20-1\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	RADIL HEG1 PLXDC1	5.44e-04	174	41	3	1d157f7a919c8246e83d8060d2a0017c6c781ef3
ToppCell	facs-Lung-EPCAM-18m-Mesenchymal-pericyte_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GUCY1A2 PLXDC1 RGCC	5.53e-04	175	41	3	a7310950e8d51b3004ea3aee8ce9948fe8655112
ToppCell	facs\|World / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HEG1 KLF13 NSD3	5.53e-04	175	41	3	53e96956019f984decc1c81376ebc88fbf3c4d40
ToppCell	5'-Adult-LymphNode-Hematopoietic-Plasma_cells\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	KLF13 CEP128 MEF2C	5.53e-04	175	41	3	6a093c74a6f3daeff07759d6eec542fc5c709149
ToppCell	facs-Lung-3m-Mesenchymal-myofibroblast-pericyte_cell-pericyte\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	GUCY1A2 PLXDC1 RGCC	5.53e-04	175	41	3	fb91a45763e4c48d993094a13088ffc19f1e2574
ToppCell	droplet-Lung-LUNG-30m-Myeloid-Ccr7+_Dendritic\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CACNB3 CACNB4 GUCY1A2	5.53e-04	175	41	3	91cb819a1786020713b7e64480de0545380daae9
ToppCell	356C-Lymphocytic-ILC\|356C / Donor, Lineage, Cell class and subclass (all cells)	PLXDC1 ZFP36L2 RGCC	5.53e-04	175	41	3	7fa8330ce813c48bd332be618909e5ec8d0f5d7e
ToppCell	facs-Lung-EPCAM-18m-Mesenchymal-Pericyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GUCY1A2 PLXDC1 RGCC	5.53e-04	175	41	3	d2ff8fedca9039cbd45cfd9dec88f4edbe7fe4fc
ToppCell	facs-Brain_Myeloid-Cerebellum-3m-Myeloid-microglial_cell\|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KDM7A ZFP36L2 MEF2A	5.53e-04	175	41	3	1ea6cf9da26601646f57fa14d558a5e9e1f0b345
ToppCell	facs-Lung-3m-Mesenchymal-myofibroblast-pericyte_cell\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	GUCY1A2 PLXDC1 RGCC	5.53e-04	175	41	3	2a53d4f140d5ab096efe8118d8aa351db7838b49
ToppCell	droplet-Lung-3m-Mesenchymal-myofibroblast-pericyte_cell-pericyte\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	GUCY1A2 PLXDC1 RGCC	5.62e-04	176	41	3	e2b59a904c5c8f9c88e1e63788e9b6485f22edd0
ToppCell	5'-GW_trimst-1.5-SmallIntestine-Mesenchymal-Pericytes-angiogenic_pericyte\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	GUCY1A2 STAG3 MEF2C	5.62e-04	176	41	3	8b5c2fb7e5e551df658b1d5fc7f607a27bab00d5
ToppCell	droplet-Lung-3m-Mesenchymal-myofibroblast-pericyte_cell\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	GUCY1A2 PLXDC1 RGCC	5.62e-04	176	41	3	f931192e3cc65414e2245354f443473696cc7ce8
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte-\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	GUCY1A2 PLXDC1 MEF2C	5.72e-04	177	41	3	4943d040eee0f9dceaddc7498171281d170e271f
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	GUCY1A2 PLXDC1 MEF2C	5.72e-04	177	41	3	a8625d14682183cf77cb51eaf11bc15a3528f586
ToppCell	droplet-Lung-30m-Hematologic-myeloid-myeloid_dendritic_cell-Ccr7+_dendritic\|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CACNB3 CACNB4 GUCY1A2	5.72e-04	177	41	3	4672cc75225a4a23b298afa8ce439628262519db
ToppCell	356C-Lymphocytic-ILC\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	PLXDC1 ZFP36L2 RGCC	5.72e-04	177	41	3	7ddd7d1854ad42abd630ad0c702105102cec93e7
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	GUCY1A2 PLXDC1 MEF2C	5.72e-04	177	41	3	3f2272b577c862dba8ccfb41184054bbd0ace6f5
ToppCell	3'-Parenchyma_lung-Epithelial-Airway_epithelium-respiratory_basal_cell-Basal_resting-Basal_resting_L.0.0.0.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	RADIL C5 TENM2	5.72e-04	177	41	3	75cb2067a3f2d1b5a964890b02b604d1e79bd163
Drug	Aspartic acid, N-acetyl (R,S) [997-55-7]; Down 200; 22.8uM; PC3; HT_HG-U133A	CACNB3 C5 GUCY1A2 ZFP36L2 RGCC NSD3	1.44e-06	199	41	6	4007_DN
Drug	cyclopentenyl cytosine	AHCYL2 CTPS2 CTPS1	5.15e-06	19	41	3	CID000072828
Drug	Camptothecine (S,+) [7689-03-4]; Down 200; 11.4uM; PC3; HT_HG-U133A	PUM2 TACC2 IRS1 MEF2C PPP1R12A	1.74e-05	180	41	5	4541_DN
Drug	Niclosamide [50-65-7]; Down 200; 12.2uM; PC3; HT_HG-U133A	CACNB3 SMG7 ZFP36L2 MEF2C RGCC	2.37e-05	192	41	5	4018_DN
Drug	Ethynylestradiol 3-methyl ether [72-33-3]; Down 200; 12.8uM; PC3; HT_HG-U133A	NKTR HEG1 KLF13 ZFP36L2 RGCC	2.62e-05	196	41	5	4208_DN
Drug	Clonidine hydrochloride [4205-91-8]; Up 200; 15uM; PC3; HT_HG-U133A	HEG1 GUCY1A2 PLXDC1 KLF13 RGCC	2.68e-05	197	41	5	4478_UP
Drug	Altretamine [654-05-6]; Down 200; 19uM; MCF7; HT_HG-U133A	CACNB3 NKTR HEG1 STAG3 NSD3	2.75e-05	198	41	5	5688_DN
Drug	Reserpinic acid hydrochloride; Down 200; 9.2uM; MCF7; HT_HG-U133A	KRI1 CACNB3 NKTR AHCYL2 C5	2.75e-05	198	41	5	7323_DN
Drug	2-propylpentanoic acid; Up 200; 50uM; PC3; HT_HG-U133A	SMG7 KLF13 ZFP36L2 RGCC NSD3	2.75e-05	198	41	5	4446_UP
Drug	Lynestrenol [52-76-6]; Down 200; 14uM; MCF7; HT_HG-U133A	KDM7A AHCYL2 SMG7 ZFP36L2 STAG3	2.75e-05	198	41	5	1537_DN
Drug	Guanethidine sulfate [60-02-6]; Up 200; 13.4uM; HL60; HG-U133A	ZGPAT HEG1 AHCYL2 KLF13 NSD3	2.81e-05	199	41	5	1554_UP
Drug	Alfadolone acetate [23930-37-2]; Down 200; 10.2uM; PC3; HT_HG-U133A	ZGPAT NKTR AHCYL2 C5 MEF2C	2.81e-05	199	41	5	7262_DN
Drug	Trazodone hydrochloride [25332-39-2]; Down 200; 9.8uM; MCF7; HT_HG-U133A	TACC2 NKTR AHCYL2 ZFP36L2 MEF2A	2.88e-05	200	41	5	7410_DN
Drug	AC1NBU2S	CACNB3 CACNB4 GUCY1A2 PLXDC1	5.79e-05	117	41	4	CID004473765
Drug	Nimodipine	CACNB3 CACNB4	1.13e-04	9	41	2	DB00393
Drug	chrysene	MUC16 ACIN1 TACC2 NKTR AHCYL2 C5 TENM2 MEF2C	1.38e-04	871	41	8	ctd:C031180
Drug	arginine hydroxamate	CTPS2 CTPS1	1.41e-04	10	41	2	CID000151275
Drug	1400 W	C5 GUCY1A2 MEF2C	1.64e-04	59	41	3	CID000001433
Drug	Mibefradil	CACNB3 CACNB4	1.72e-04	11	41	2	DB01388
Drug	15d-PGJ2; Up 200; 10uM; MCF7; HT_HG-U133A_EA	ANKRD11 HEG1 MEF2A RGCC	1.90e-04	159	41	4	1011_UP
Drug	AICAR monophosphate	IRS1 MEF2A MEF2C PPP1R12A	2.09e-04	163	41	4	CID000000200
Drug	thioridazine hydrochloride; Up 200; 10uM; PC3; HT_HG-U133A	KDM7A SMG7 KLF13 NSD3	2.34e-04	168	41	4	4454_UP
Drug	15d-PGJ2; Up 200; 10uM; MCF7; HT_HG-U133A	ANKRD11 SMG7 STAG3 RGCC	2.45e-04	170	41	4	1656_UP
Drug	Trichostatin A, from Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A	CACNB3 IRS1 CTPS1 ZFP36L2	2.50e-04	171	41	4	7407_DN
Drug	irinotecan HCl; Down 200; 100uM; PC3; HT_HG-U133A	ANKRD11 TACC2 MEF2C PPP1R12A	2.50e-04	171	41	4	7535_DN
Drug	Trichostatin A, Streptomyces sp.; Down 200; 1uM; MCF7; HT_HG-U133A_EA	PUM2 TACC2 IRS1 ZFP36L2	2.56e-04	172	41	4	1072_DN
Drug	trichostatin A, Streptomyces sp.; Down 200; 1uM; MCF7; HT_HG-U133A	IRS1 SMG7 CTPS1 ZFP36L2	2.74e-04	175	41	4	6891_DN
Drug	trichostatin A; Down 200; 0.1uM; MCF7; HG-U133A	ACIN1 TACC2 IRS1 ZFP36L2	2.98e-04	179	41	4	331_DN
Drug	Camptothecine (S,+) [7689-03-4]; Down 200; 11.4uM; MCF7; HT_HG-U133A	PUM2 TACC2 IRS1 PPP1R12A	3.18e-04	182	41	4	3887_DN
Drug	Adiphenine hydrochloride [50-42-0]; Down 200; 11.4uM; MCF7; HT_HG-U133A	C5 SMG7 ZFP36L2 PPP1R12A	3.24e-04	183	41	4	1709_DN
Drug	AC1L2Q2B	AHCYL2 CTPS1	3.27e-04	15	41	2	CID000126283
Drug	bacilysin	CTPS2 CTPS1	3.27e-04	15	41	2	CID000160175
Drug	trichostatin A, Streptomyces sp.; Down 200; 1uM; MCF7; HT_HG-U133A	CACNB3 IRS1 SMG7 ZFP36L2	3.31e-04	184	41	4	6916_DN
Drug	Rapamycin; Up 200; 0.1uM; PC3; HT_HG-U133A	GUCY1A2 KLF13 RGCC NSD3	3.38e-04	185	41	4	4445_UP
Drug	GW8510; Down 200; 10uM; MCF7; HT_HG-U133A	PUM2 TACC2 IRS1 ZFP36L2	3.52e-04	187	41	4	7080_DN
Drug	Theophylline	IRS1 C5 CTPS1 YJU2B MEF2A NSD3	3.55e-04	532	41	6	ctd:D013806
Drug	CP-690334-01 [459212-38-5]; Up 200; 10uM; PC3; HT_HG-U133A	NKTR AHCYL2 SMG7 AGBL3	3.59e-04	188	41	4	3823_UP
Drug	Nifuroxazide [965-52-6]; Down 200; 14.6uM; MCF7; HT_HG-U133A	CACNB3 NKTR KLF13 ZFP36L2	3.59e-04	188	41	4	4835_DN
Drug	Verapamil	CACNB3 CACNB4	3.74e-04	16	41	2	DB00661
Drug	15d-PGJ2; Down 200; 10uM; HL60; HT_HG-U133A	KLF13 ZFP36L2 MEF2C RFWD3	3.74e-04	190	41	4	1172_DN
Drug	0297417-0002B [362658-29-5]; Down 200; 10uM; MCF7; HT_HG-U133A	C5 SMG7 CTPS1 RFWD3	3.81e-04	191	41	4	6900_DN
Drug	Corynanthine hydrochloride [66634-44-4]; Down 200; 10.2uM; MCF7; HT_HG-U133A	KRI1 SMG7 ZFP36L2 STAG3	3.81e-04	191	41	4	4811_DN
Drug	Albendazole [54965-21-8]; Down 200; 15uM; MCF7; HT_HG-U133A	AHCYL2 SMG7 ZFP36L2 NSD3	3.89e-04	192	41	4	3164_DN
Drug	Clorgyline hydrochloride [17780-75-5]; Down 200; 13uM; PC3; HT_HG-U133A	SMG7 ZFP36L2 MEF2C RFWD3	3.89e-04	192	41	4	6659_DN
Drug	Leflunomide [75706-12-6]; Down 200; 14.8uM; MCF7; HT_HG-U133A	HEG1 ZFP36L2 STAG3 RGCC	3.89e-04	192	41	4	6102_DN
Drug	2-propylpentanoic acid; Up 200; 1000uM; SKMEL5; HG-U133A	TRPM8 KDM7A AHCYL2 MEF2C	3.89e-04	192	41	4	629_UP
Drug	PF-00539758-00 [351321-34-1]; Up 200; 10uM; PC3; HT_HG-U133A	CACNB3 AHCYL2 SMG7 ZFP36L2	3.97e-04	193	41	4	6421_UP
Drug	PF-00562151-00 [351320-12-2]; Up 200; 10uM; PC3; HT_HG-U133A	CACNB3 HEG1 SMG7 STAG3	3.97e-04	193	41	4	5922_UP
Drug	geldanamycin; Down 200; 1uM; MCF7; HT_HG-U133A	CACNB3 IRS1 C5 ZFP36L2	3.97e-04	193	41	4	6946_DN
Drug	Nifuroxazide [965-52-6]; Down 200; 14.6uM; PC3; HT_HG-U133A	KLF13 ZFP36L2 STAG3 NSD3	3.97e-04	193	41	4	4253_DN
Drug	pioglitazone HCl; Up 200; 10uM; PC3; HT_HG-U133A	KDM7A HEG1 RGCC NSD3	3.97e-04	193	41	4	6893_UP
Drug	Karakoline [39089-30-0]; Down 200; 10.6uM; MCF7; HT_HG-U133A	NKTR ZFP36L2 STAG3 MEF2C	4.04e-04	194	41	4	4763_DN
Drug	Omeprazole [73590-58-6]; Down 200; 11.6uM; HL60; HT_HG-U133A	IRS1 SMG7 MEF2C NSD3	4.04e-04	194	41	4	2467_DN
Drug	Methyl benzethonium chloride [25155-18-4]; Down 200; 8.6uM; PC3; HT_HG-U133A	CACNB3 ZFP36L2 STAG3 MEF2C	4.04e-04	194	41	4	4325_DN
Drug	radicicol, diheterospora chlamydosporia; Down 200; 0.1uM; MCF7; HT_HG-U133A_EA	KRI1 NKTR KDM7A ZFP36L2	4.12e-04	195	41	4	999_DN
Drug	phentolamine; Down 200; 11.5uM; MCF7; HT_HG-U133A_EA	TACC2 NKTR SMG7 MEF2A	4.12e-04	195	41	4	1138_DN
Drug	Florfenicol [73231-34-2]; Down 200; 11.2uM; PC3; HT_HG-U133A	HEG1 KLF13 ZFP36L2 RGCC	4.12e-04	195	41	4	6701_DN
Drug	17-DMAG; Down 200; 0.1uM; MCF7; HT_HG-U133A	CACNB3 SMG7 ZFP36L2 STAG3	4.12e-04	195	41	4	6973_DN
Drug	Mycophenolic acid [24280-93-1]; Down 200; 12.4uM; PC3; HT_HG-U133A	ANKRD11 AHCYL2 ZFP36L2 NSD3	4.12e-04	195	41	4	4019_DN
Drug	Androsterone [53-41-8]; Down 200; 13.8uM; HL60; HT_HG-U133A	ZGPAT SMG7 ZFP36L2 MEF2C	4.12e-04	195	41	4	1296_DN
Drug	6-Hydroxytropinone [5932-53-6]; Down 200; 25.8uM; PC3; HT_HG-U133A	KLF13 ZFP36L2 STAG3 RGCC	4.12e-04	195	41	4	4250_DN
Drug	Rapamycin; Up 200; 0.1uM; HL60; HT_HG-U133A	CACNB3 CACNB4 PLXDC1 ZFP36L2	4.12e-04	195	41	4	2702_UP
Drug	Acacetin [480-44-4]; Down 200; 14uM; PC3; HT_HG-U133A	CACNB3 AHCYL2 ZFP36L2 NSD3	4.12e-04	195	41	4	4324_DN
Drug	Alfaxalone [23930-19-0]; Down 200; 12uM; HL60; HT_HG-U133A	CACNB3 HEG1 SMG7 STAG3	4.12e-04	195	41	4	3135_DN
Drug	Riluzole hydrochloride; Down 200; 14.8uM; MCF7; HT_HG-U133A	NKTR AHCYL2 ZFP36L2 STAG3	4.20e-04	196	41	4	4689_DN
Drug	Diprophylline [479-18-5]; Down 200; 15.8uM; PC3; HT_HG-U133A	CACNB3 SMG7 KLF13 STAG3	4.20e-04	196	41	4	5063_DN
Drug	Bisoprolol fumarate; Down 200; 9uM; PC3; HT_HG-U133A	NKTR HEG1 ZFP36L2 MEF2C	4.20e-04	196	41	4	6748_DN
Drug	Seneciphylline [480-81-9]; Down 200; 12uM; PC3; HT_HG-U133A	SMG7 KLF13 ZFP36L2 RGCC	4.20e-04	196	41	4	4238_DN
Drug	Thiamphenicol [15318-45-3]; Up 200; 11.2uM; HL60; HT_HG-U133A	ZGPAT NKTR SMG7 KLF13	4.20e-04	196	41	4	1867_UP
Drug	Azaperone [1649-18-9]; Down 200; 12.2uM; PC3; HT_HG-U133A	CACNB3 HEG1 C5 NSD3	4.20e-04	196	41	4	5877_DN
Drug	Oxamniquine [21738-42-1]; Down 200; 14.4uM; HL60; HT_HG-U133A	SMG7 MEF2A MEF2C NSD3	4.20e-04	196	41	4	2924_DN
Drug	Fosfosal [6064-83-1]; Down 200; 18.4uM; HL60; HT_HG-U133A	CACNB3 CACNB4 ZFP36L2 MEF2C	4.20e-04	196	41	4	2997_DN
Drug	2-propylpentanoic acid; Up 200; 200uM; MCF7; HT_HG-U133A	KDM7A SMG7 ZFP36L2 STAG3	4.20e-04	196	41	4	1639_UP
Drug	Tetracycline hydrochloride [64-75-5]; Up 200; 8.4uM; MCF7; HT_HG-U133A	PLXDC1 KLF13 ZFP36L2 MEF2C	4.20e-04	196	41	4	2243_UP
Drug	Viomycin sulfate [37883-00-4]; Down 200; 5.2uM; MCF7; HT_HG-U133A	CACNB3 KDM7A ZFP36L2 STAG3	4.20e-04	196	41	4	3541_DN
Drug	Troleandomycin [2751-09-9]; Down 200; 5uM; PC3; HT_HG-U133A	NKTR GUCY1A2 ZFP36L2 STAG3	4.20e-04	196	41	4	3985_DN
Drug	Finasteride [98319-26-7]; Down 200; 10.8uM; MCF7; HT_HG-U133A	CACNB3 NKTR AHCYL2 MEF2C	4.20e-04	196	41	4	4766_DN
Drug	Flucloxacillin sodium [1847-24-1]; Down 200; 8.4uM; MCF7; HT_HG-U133A	NKTR HEG1 AHCYL2 SMG7	4.29e-04	197	41	4	6507_DN
Drug	Ethoxyquin [91-53-2]; Down 200; 18.4uM; HL60; HT_HG-U133A	HEG1 SMG7 ZFP36L2 MEF2C	4.29e-04	197	41	4	2559_DN
Drug	Yohimbine hydrochloride [65-19-0]; Down 200; 10.2uM; PC3; HT_HG-U133A	TACC2 NKTR AHCYL2 NSD3	4.29e-04	197	41	4	7130_DN
Drug	Dorzolamide hydrochloride [130693-82-2]; Down 200; 11uM; PC3; HT_HG-U133A	NKTR AHCYL2 RGCC NSD3	4.29e-04	197	41	4	5785_DN
Drug	Methylhydantoin-5-(D) [55147-68-7]; Down 200; 35uM; HL60; HT_HG-U133A	CACNB3 CACNB4 SMG7 PLXDC1	4.29e-04	197	41	4	2994_DN
Drug	Nafcillin sodium salt monohydrate [7177-50-6]; Down 200; 8.8uM; PC3; HT_HG-U133A	ZFP36L2 STAG3 MEF2C NSD3	4.29e-04	197	41	4	3983_DN
Drug	Memantine Hydrochloride [41100-52-1]; Down 200; 18.6uM; HL60; HT_HG-U133A	NKTR KDM7A ZFP36L2 STAG3	4.29e-04	197	41	4	2934_DN
Drug	Flurbiprofen [5104-49-4]; Down 200; 16.4uM; PC3; HT_HG-U133A	NKTR AHCYL2 ZFP36L2 STAG3	4.29e-04	197	41	4	4674_DN
Drug	Diltiazem hydrochloride [33286-22-5]; Up 200; 8.8uM; MCF7; HT_HG-U133A	CACNB3 C5 SMG7 ZFP36L2	4.29e-04	197	41	4	5309_UP
Drug	Demeclocycline hydrochloride [64-73-3]; Down 200; 8uM; HL60; HT_HG-U133A	CACNB3 CTPS2 ZFP36L2 MEF2C	4.29e-04	197	41	4	2545_DN
Drug	3-alpha-Hydroxy-5-beta-androstan-17-one [53-42-9]; Down 200; 13.8uM; MCF7; HT_HG-U133A	NKTR SMG7 GUCY1A2 MEF2C	4.29e-04	197	41	4	4764_DN
Drug	Xylazine [7361-61-7]; Down 200; 18.2uM; MCF7; HT_HG-U133A	AHCYL2 C5 SMG7 ZFP36L2	4.29e-04	197	41	4	2788_DN
Drug	Amiloride hydrochloride dihydrate [17440-83-4]; Down 200; 13.2uM; PC3; HT_HG-U133A	CACNB3 ZFP36L2 RGCC NSD3	4.37e-04	198	41	4	3990_DN
Drug	iloprost; Down 200; 1uM; SKMEL5; HG-U133A	ZGPAT NKTR ZFP36L2 STAG3	4.37e-04	198	41	4	496_DN
Drug	arachidonyl trifluoromethyl ketone; Down 200; 10uM; MCF7; HG-U133A	KRI1 ZGPAT C5 NSD3	4.37e-04	198	41	4	594_DN
Drug	Diperodon hydrochloride [537-12-2]; Down 200; 9.2uM; PC3; HT_HG-U133A	CACNB3 HEG1 ZFP36L2 MEF2C	4.37e-04	198	41	4	4498_DN
Drug	Bufexamac [2438-72-4]; Down 200; 18uM; MCF7; HT_HG-U133A	NKTR SMG7 MEF2A NSD3	4.37e-04	198	41	4	5515_DN
Drug	Azathymine, 6 [932-53-6]; Down 200; 31.4uM; PC3; HT_HG-U133A	CACNB3 GUCY1A2 MEF2C RGCC	4.37e-04	198	41	4	3987_DN
Drug	Urapidil hydrochloride [64887-14-5]; Up 200; 9.4uM; MCF7; HT_HG-U133A	HEG1 AHCYL2 SMG7 ZFP36L2	4.37e-04	198	41	4	5295_UP
Drug	Asiaticoside [16830-15-2]; Down 200; 4.2uM; HL60; HT_HG-U133A	IRS1 SMG7 ZFP36L2 NSD3	4.37e-04	198	41	4	2943_DN
Drug	Meclofenamic acid sodium salt monohydrate [6385-02-0]; Up 200; 11.8uM; PC3; HT_HG-U133A	HEG1 SMG7 MEF2A MEF2C	4.37e-04	198	41	4	2128_UP
Drug	Mephenesin [59-47-2]; Down 200; 22uM; MCF7; HT_HG-U133A	KLF13 ZFP36L2 YJU2B NSD3	4.37e-04	198	41	4	4698_DN
Drug	Heptaminol hydrochloride [543-15-7]; Up 200; 22uM; PC3; HT_HG-U133A	KLF13 ZFP36L2 STAG3 NSD3	4.37e-04	198	41	4	7313_UP
Disease	intellectual disability (implicated_via_orthology)	IRS1 MEF2A MEF2C	1.46e-04	75	40	3	DOID:1059 (implicated_via_orthology)
Disease	Epilepsy	ANKRD11 CACNB4 MEF2C	4.39e-04	109	40	3	C0014544
Disease	attention deficit hyperactivity disorder (implicated_via_orthology)	MEF2A MEF2C	6.62e-04	28	40	2	DOID:1094 (implicated_via_orthology)
Disease	dilated cardiomyopathy (is_implicated_in)	CACNB4 MEF2A	1.56e-03	43	40	2	DOID:12930 (is_implicated_in)
Disease	Tourette syndrome	MUC16 TENM2	2.11e-03	50	40	2	EFO_0004895

Protein segments in the cluster

Peptide	Gene	Start	Entry
SRDSSTSYTETKDPS	ACIN1	661	Q9UKV3
RGSDSSESIDSLTYL	AGBL3	616	Q8NEM8
RDSCSSSERTDGRYS	CEP128	986	Q6ZU80
SDSTRTRLTSESDYS	ANKRD11	566	Q6UB99
TRLTSESDYSSEGSS	ANKRD11	571	Q6UB99
GSADSYTSRPSLDSD	CACNB3	16	P54284
SSQSGDSESDSDSYS	DDX20	646	Q9UHI6
SADSYTSRPSDSDVS	CACNB4	51	O00305
SSSSDSDSDSSAEYG	RFWD3	211	Q6PCD5
SATRRESLSTSSDLY	PUM2	581	Q8TB72
YRDLDSTFSSLGASD	RADIL	36	Q96JH8
LSSTAGEALSTYEAS	MUC16	4221	Q8WXI7
SRSSGYSDISESEDS	KDM7A	651	Q6ZMT4
IYEDRCSSGSSSSGS	GOLGA7B	136	Q2TAP0
LSSSTSSTDKSDGDY	NEK4	681	P51957
SERSGYTDSESSASL	DCAF5	451	Q96JK2
YGDRDSSSDSSSESD	KRI1	36	Q8N9T8
TEYSLSSADLSSLSG	MEF2C	321	Q06413
ALGDRSYSESSSTSS	HEG1	501	Q9ULI3
DSLSSSSSSYDGSDR	MEF2A	456	Q02078
GRLLYAATADDSSSS	IRS1	796	P35568
SSSTRRSSEDLSAYA	IRS1	1216	P35568
ASYKPSREESSSGSS	C5	1406	P01031
TGSLSDYSRSDASSP	KLF13	266	Q9Y2Y9
ISSESFSSLGSDYLE	GUCY1A2	6	P33402
SSSSTSSAGADVDYS	REXO1	586	Q8N1G1
YSSAASYTDSSDDET	AHCYL2	156	Q96HN2
SSSYTSISSDDGRRA	NKTR	741	P30414
SRSSLDYSSDSEQSS	NKTR	801	P30414
FGIDYLSATSSSESS	SMG7	1056	Q92540
LSPRDTYSDRSGSSS	CTPS1	561	P17812
TYSDRSGSSSPDSEI	CTPS1	566	P17812
GYSLSTGSDADSDTE	TENM2	106	Q9NT68
LSSSDRYSDASDDSF	CTPS2	561	Q9NRF8
ASSYSSTSERGLDLL	STAG3	1201	Q9UJ98
TRSGSSDSSYDFLST	SARG	31	Q9BW04
SSGFSDSESADSLYR	RGCC	71	Q9H4X1
SSSEDTAYLGTLASS	MYCBPAP	381	Q8TBZ2
DAYSTGSSSASSTLK	TACC2	2111	O95359
SLGSSLVADYSDSES	YJU2B	381	P13994
AYRDTSDSDSRGLSD	NSD3	646	Q9BZ95
YDGDLTTTSSSLFID	PLXDC1	376	Q8IUK5
DTLDSTRTLYSSASR	TRPM8	16	Q7Z2W7
SSASRSTDLSYSESD	TRPM8	26	Q7Z2W7
DSLSDRDSYLSGSLS	ZFP36L2	451	P47974
SDSDSDGTGDSSYAR	ZGPAT	276	Q8N5A5
SISRYETSSTSAGDR	PPP1R12A	886	O14974
ETSSTSAGDRYDSLL	PPP1R12A	891	O14974