Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	phosphoric diester hydrolase activity	PLCZ1 GDPD2 PDE8B PLCB2 PLCB3 PLD1 MPPED2	1.36e-05	97	161	7	GO:0008081
GeneOntologyMolecularFunction	calcium ion binding	UNC13B PLCZ1 DCHS2 FAT4 MAN1A1 PNLIPRP2 PCDHGA1 FAT3 IQGAP1 TGM2 FAT2 HEG1 PCDH19 LRP1 PLCB2 PLCB3 UNC13A	1.19e-04	749	161	17	GO:0005509
Domain	PBC	PBX4 PBX1 PBX3	2.45e-06	4	160	3	PF03792
Domain	PBX	PBX4 PBX1 PBX3	2.45e-06	4	160	3	IPR005542
Domain	-	PLCZ1 GDPD2 PLCB2 PLCB3	5.70e-05	25	160	4	3.20.20.190
Domain	PLC-like_Pdiesterase_TIM-brl	PLCZ1 GDPD2 PLCB2 PLCB3	5.70e-05	25	160	4	IPR017946
Domain	ST7	ST7 ST7L	7.29e-05	2	160	2	PF04184
Domain	ST7	ST7 ST7L	7.29e-05	2	160	2	IPR007311
Domain	C2	UNC13B PLCZ1 NEDD4 PLCB2 PLCB3 CPNE4 UNC13A	1.36e-04	131	160	7	PF00168
Domain	C2	UNC13B PLCZ1 NEDD4 PLCB2 PLCB3 CPNE4 UNC13A	1.80e-04	137	160	7	SM00239
Domain	PLC-beta_C	PLCB2 PLCB3	2.18e-04	3	160	2	PF08703
Domain	PLC-beta_C	PLCB2 PLCB3	2.18e-04	3	160	2	IPR014815
Domain	Unc-13	UNC13B UNC13A	2.18e-04	3	160	2	IPR027080
Domain	C2	UNC13B PLCZ1 NEDD4 PLCB2 PLCB3 CPNE4 UNC13A	2.24e-04	142	160	7	PS50004
Domain	EF-hand_like	PLCZ1 PLCB2 PLCB3	2.60e-04	15	160	3	PF09279
Domain	PI-PLC-Y	PLCZ1 PLCB2 PLCB3	2.60e-04	15	160	3	PF00387
Domain	PLCYc	PLCZ1 PLCB2 PLCB3	2.60e-04	15	160	3	SM00149
Domain	PLipase_C_Pinositol-sp_Y	PLCZ1 PLCB2 PLCB3	2.60e-04	15	160	3	IPR001711
Domain	PIPLC_Y_DOMAIN	PLCZ1 PLCB2 PLCB3	2.60e-04	15	160	3	PS50008
Domain	PI-PLC_fam	PLCZ1 PLCB2 PLCB3	2.60e-04	15	160	3	IPR001192
Domain	PLC_EF-hand-like	PLCZ1 PLCB2 PLCB3	2.60e-04	15	160	3	IPR015359
Domain	-	UNC13B PLCZ1 NEDD4 PLCB2 PLCB3 CPNE4 UNC13A	2.89e-04	148	160	7	2.60.40.150
Domain	LAM_G_DOMAIN	FAT4 FAT3 LAMA1 FAT2	3.05e-04	38	160	4	PS50025
Domain	Cadherin_CS	DCHS2 FAT4 PCDHGA1 FAT3 FAT2 PCDH19	3.52e-04	109	160	6	IPR020894
Domain	Laminin_G_2	FAT4 FAT3 LAMA1 FAT2	3.73e-04	40	160	4	PF02210
Domain	CADHERIN_1	DCHS2 FAT4 PCDHGA1 FAT3 FAT2 PCDH19	4.27e-04	113	160	6	PS00232
Domain	Cadherin	DCHS2 FAT4 PCDHGA1 FAT3 FAT2 PCDH19	4.27e-04	113	160	6	PF00028
Domain	Glycine_N-acyltransferase_C	GLYAT GLYATL2	4.33e-04	4	160	2	IPR013652
Domain	Glycine_N-acyltransferase	GLYAT GLYATL2	4.33e-04	4	160	2	IPR010313
Domain	Ostalpha/TMEM184C	TMEM184A TMEM184B	4.33e-04	4	160	2	IPR005178
Domain	PLC-beta	PLCB2 PLCB3	4.33e-04	4	160	2	IPR016280
Domain	Glycine_N-acyltransferase_N	GLYAT GLYATL2	4.33e-04	4	160	2	IPR015938
Domain	Gly_acyl_tr_C	GLYAT GLYATL2	4.33e-04	4	160	2	PF08444
Domain	Gly_acyl_tr_N	GLYAT GLYATL2	4.33e-04	4	160	2	PF06021
Domain	Solute_trans_a	TMEM184A TMEM184B	4.33e-04	4	160	2	PF03619
Domain	CADHERIN_2	DCHS2 FAT4 PCDHGA1 FAT3 FAT2 PCDH19	4.48e-04	114	160	6	PS50268
Domain	-	DCHS2 FAT4 PCDHGA1 FAT3 FAT2 PCDH19	4.48e-04	114	160	6	2.60.40.60
Domain	PI-PLC-X	PLCZ1 PLCB2 PLCB3	4.58e-04	18	160	3	PF00388
Domain	PLCXc	PLCZ1 PLCB2 PLCB3	4.58e-04	18	160	3	SM00148
Domain	CA	DCHS2 FAT4 PCDHGA1 FAT3 FAT2 PCDH19	4.69e-04	115	160	6	SM00112
Domain	Cadherin-like	DCHS2 FAT4 PCDHGA1 FAT3 FAT2 PCDH19	4.91e-04	116	160	6	IPR015919
Domain	C2_dom	UNC13B PLCZ1 NEDD4 PLCB2 PLCB3 CPNE4 UNC13A	5.37e-04	164	160	7	IPR000008
Domain	Cadherin	DCHS2 FAT4 PCDHGA1 FAT3 FAT2 PCDH19	5.38e-04	118	160	6	IPR002126
Domain	LamG	FAT4 FAT3 LAMA1 FAT2	5.39e-04	44	160	4	SM00282
Domain	PIPLC_X_DOMAIN	PLCZ1 PLCB2 PLCB3	5.41e-04	19	160	3	PS50007
Domain	PLipase_C_PInositol-sp_X_dom	PLCZ1 PLCB2 PLCB3	5.41e-04	19	160	3	IPR000909
Domain	Munc13_dom-2	UNC13B UNC13A	7.17e-04	5	160	2	IPR014772
Domain	MHD2	UNC13B UNC13A	7.17e-04	5	160	2	PS51259
Domain	Munc13_subgr_dom-2	UNC13B UNC13A	7.17e-04	5	160	2	IPR019558
Domain	Membr_traf_MHD	UNC13B UNC13A	7.17e-04	5	160	2	PF10540
Domain	DUF1041	UNC13B UNC13A	7.17e-04	5	160	2	SM01145
Domain	Munc13_1	UNC13B UNC13A	1.49e-03	7	160	2	IPR014770
Domain	MHD1	UNC13B UNC13A	1.49e-03	7	160	2	PS51258
Domain	DUF1041	UNC13B UNC13A	1.49e-03	7	160	2	PF06292
Domain	CAPS_dom	UNC13B UNC13A	1.49e-03	7	160	2	IPR010439
Domain	Laminin_G	FAT4 FAT3 LAMA1 FAT2	1.54e-03	58	160	4	IPR001791
Domain	EGF_1	FAT4 FN1 FAT3 LAMA1 MEP1A FAT2 HEG1 LRP1	1.62e-03	255	160	8	PS00022
Domain	EGF-like_CS	FAT4 FN1 FAT3 LAMA1 MEP1A FAT2 HEG1 LRP1	1.88e-03	261	160	8	IPR013032
Domain	K_chnl_volt-dep_Kv1	KCNA4 KCNA10	1.97e-03	8	160	2	IPR003972
Domain	C1Q	C1QL3 C1QL4 C1QL1	2.55e-03	32	160	3	SM00110
Domain	C1q	C1QL3 C1QL4 C1QL1	2.55e-03	32	160	3	PF00386
Domain	SH3	DOCK2 FNBP1 KALRN ARHGAP4 NGEF ARHGEF37 SNX9	2.63e-03	216	160	7	SM00326
Domain	SH3	DOCK2 FNBP1 KALRN ARHGAP4 NGEF ARHGEF37 SNX9	2.63e-03	216	160	7	PS50002
Pubmed	Expression of mouse dchs1, fjx1, and fat-j suggests conservation of the planar cell polarity pathway identified in Drosophila.	DCHS2 FAT4 FAT3 FAT2	1.73e-08	7	166	4	16059920
Pubmed	USP7 targets XIAP for cancer progression: Establishment of a p53-independent therapeutic avenue for glioma.	DNHD1 MYH13 ZGRF1 FAT3 LAMA1 THOC2 SENP1 FAT2 KMT2D KIAA1549L NGEF	1.91e-08	234	166	11	36243803
Pubmed	Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.	FNBP1 DCAF8 ST7 ASH1L HECTD4 STAP2 HIPK2 ZSWIM6 BABAM2 SENP1 FAM13A TMEM184A ATXN2 FBXO42 NGEF LRP1 SLC9A7 SCP2 ARHGEF37 PBX1 PBX3 SNX9 CLEC16A GOLGA4	1.88e-07	1489	166	24	28611215
Pubmed	Hypomorphic mutation of the TALE gene Prep1 (pKnox1) causes a major reduction of Pbx and Meis proteins and a pleiotropic embryonic phenotype.	PBX4 PBX1 PBX3 MYB	3.46e-07	13	166	4	16847320
Pubmed	Tissue transglutaminase mediates the pro-malignant effects of oncostatin M receptor over-expression in cervical squamous cell carcinoma.	FN1 TGM2 OSMR	4.26e-07	4	166	3	23765377
Pubmed	Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.	UNC13B DCHS2 DCAF8 FN1 KALRN HIPK1 ASH1L HECTD4 NUP42 IQGAP1 USP2 NAA25 NGEF LRP1 MORC3 HERC2 PBX1 PBX3 MPPED2 AGTPBP1 KLHL4	9.46e-07	1285	166	21	35914814
Pubmed	The cell-adhesion G protein-coupled receptor BAI3 is a high-affinity receptor for C1q-like proteins.	C1QL3 C1QL4 C1QL1	1.06e-06	5	166	3	21262840
Pubmed	Transcription factor PBX4 regulates limb development and haematopoiesis in mice.	PBX4 PBX1 PBX3	1.06e-06	5	166	3	38230761
Pubmed	Pbx4, a new Pbx family member on mouse chromosome 8, is expressed during spermatogenesis.	PBX4 PBX1 PBX3	1.06e-06	5	166	3	11335119
Pubmed	Requirement of FAT and DCHS protocadherins during hypothalamic-pituitary development.	DCHS2 FAT4 FAT3 FAT2	1.45e-06	18	166	4	33108146
Pubmed	Distinct expression of C1q-like family mRNAs in mouse brain and biochemical characterization of their encoded proteins.	C1QL3 C1QL4 C1QL1	2.11e-06	6	166	3	20525073
Pubmed	An improved smaller biotin ligase for BioID proximity labeling.	ASH1L CCDC168 NUP42 FSIP2 SENP1 ZFP36L2 NGEF	2.22e-06	123	166	7	26912792
Pubmed	Paralog knockout profiling identifies DUSP4 and DUSP6 as a digenic dependence in MAPK pathway-driven cancers.	PLCZ1 PMPCB HIPK1 HIPK2 NEDD4 TGM2 SENP1 KCNA4 KCNA10 ADAMTS6 LRP1 PCSK7 PLCB2 PLCB3 SEC23A	2.51e-06	730	166	15	34857952
Pubmed	Hdac4 Interactions in Huntington's Disease Viewed Through the Prism of Multiomics.	DCAF8 FN1 KALRN INTS7 ITIH3 IQGAP1 SENP1 ATXN2 NGEF SCP2 PLCB3 HERC2	3.35e-06	475	166	12	31040226
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	UNC13B PALD1 FNBP1 ZFYVE16 HIPK1 ZSWIM6 CSMD3 NEDD4 PCDH19 CLEC16A AGTPBP1	4.59e-06	407	166	11	12693553
Pubmed	Embryonic poly(A)-binding protein (EPAB) is required for oocyte maturation and female fertility in mice.	DAZ4 DAZ1 PABPC3	5.88e-06	8	166	3	22621333
Pubmed	Characterization of a novel gene adjacent to PAX6, revealing synteny conservation with functional significance.	KCNA4 KIAA1549L MPPED2	1.25e-05	10	166	3	11889558
Pubmed	Transcriptional mechanisms of EphA7 gene expression in the developing cerebral cortex.	FN1 CPNE4 PBX1	1.71e-05	11	166	3	21940705
Pubmed	MLL4 is required after implantation, whereas MLL3 becomes essential during late gestation.	FN1 LAMA1 KMT2D CLIC5	1.84e-05	33	166	4	32439762
Pubmed	Cancer cell-derived microvesicles induce transformation by transferring tissue transglutaminase and fibronectin to recipient cells.	FN1 TGM2	2.26e-05	2	166	2	21368175
Pubmed	TSH receptor interaction with the extracellular matrix: role on constitutive activity and sensitivity to hormonal stimulation.	FN1 TSHR	2.26e-05	2	166	2	11981027
Pubmed	Regulation of insulin exocytosis by Munc13-1.	UNC13B UNC13A	2.26e-05	2	166	2	12871971
Pubmed	Formation of perineuronal nets in organotypic mouse brain slice cultures is independent of neuronal glutamatergic activity.	UNC13B UNC13A	2.26e-05	2	166	2	17561838
Pubmed	HIPK1 interacts with c-Myb and modulates its activity through phosphorylation.	HIPK1 MYB	2.26e-05	2	166	2	19646965
Pubmed	Heterodimerization of Munc13 C2A domain with RIM regulates synaptic vesicle docking and priming.	UNC13B UNC13A	2.26e-05	2	166	2	28489077
Pubmed	Transglutaminase 2 strongly binds to an extracellular matrix component other than fibronectin via its second C-terminal beta-barrel domain.	FN1 TGM2	2.26e-05	2	166	2	27685605
Pubmed	Munc13-1 is essential for fusion competence of glutamatergic synaptic vesicles.	UNC13B UNC13A	2.26e-05	2	166	2	10440375
Pubmed	Inhibition of exocytosis or endocytosis blocks activity-dependent redistribution of synapsin.	UNC13B UNC13A	2.26e-05	2	166	2	22066784
Pubmed	Ultrastructural Correlates of Presynaptic Functional Heterogeneity in Hippocampal Synapses.	UNC13B UNC13A	2.26e-05	2	166	2	32187536
Pubmed	Role of mammalian homologue of Caenorhabditis elegans unc-13-1 (Munc13-1) in the recruitment of newcomer insulin granules in both first and second phases of glucose-stimulated insulin secretion in mouse islets.	UNC13B UNC13A	2.26e-05	2	166	2	22814762
Pubmed	Activation of c-MYC and c-MYB proto-oncogenes is associated with decreased apoptosis in tumor colon progression.	MYC MYB	2.26e-05	2	166	2	11848471
Pubmed	Formation and Maintenance of Functional Spines in the Absence of Presynaptic Glutamate Release.	UNC13B UNC13A	2.26e-05	2	166	2	28426965
Pubmed	Dynamic control of synaptic vesicle replenishment and short-term plasticity by Ca(2+)-calmodulin-Munc13-1 signaling.	UNC13B UNC13A	2.26e-05	2	166	2	23770256
Pubmed	Calcium-Independent Exo-endocytosis Coupling at Small Central Synapses.	UNC13B UNC13A	2.26e-05	2	166	2	31851910
Pubmed	Differential control of vesicle priming and short-term plasticity by Munc13 isoforms.	UNC13B UNC13A	2.26e-05	2	166	2	11832228
Pubmed	Munc13 controls the location and efficiency of dense-core vesicle release in neurons.	UNC13B UNC13A	2.26e-05	2	166	2	23229896
Pubmed	TIMELESS contributes to the progression of breast cancer through activation of MYC.	MYC TIMELESS	2.26e-05	2	166	2	28464854
Pubmed	Transglutaminase-2 interaction with heparin: identification of a heparin binding site that regulates cell adhesion to fibronectin-transglutaminase-2 matrix.	FN1 TGM2	2.26e-05	2	166	2	22442151
Pubmed	c-Myc is essential but not sufficient for c-Myb-mediated block of granulocytic differentiation.	MYC MYB	2.26e-05	2	166	2	12525485
Pubmed	The ZGRF1 Helicase Promotes Recombinational Repair of Replication-Blocking DNA Damage in Human Cells.	RAD51 ZGRF1	2.26e-05	2	166	2	32640219
Pubmed	Molecular cloning and characterization of mouse St7r (St7-like, St7l).	ST7 ST7L	2.26e-05	2	166	2	12060862
Pubmed	Total arrest of spontaneous and evoked synaptic transmission but normal synaptogenesis in the absence of Munc13-mediated vesicle priming.	UNC13B UNC13A	2.26e-05	2	166	2	12070347
Pubmed	Enhanced diacylglycerol production by phospholipase D activation is responsible for abnormal increase in concanavalin A cap formation in polymorphonuclear leukocytes from Chediak-Higashi syndrome (beige) mice.	LYST PLD1	2.26e-05	2	166	2	24830864
Pubmed	Homeodomain-interacting protein kinase 2 plays an important role in normal terminal erythroid differentiation.	HIPK1 HIPK2	2.26e-05	2	166	2	20231426
Pubmed	Munc13 genotype regulates secretory amyloid precursor protein processing via postsynaptic glutamate receptors.	UNC13B UNC13A	2.26e-05	2	166	2	23070049
Pubmed	Involvement of tissue transglutaminase in the stabilisation of biomaterial/tissue interfaces important in medical devices.	FN1 TGM2	2.26e-05	2	166	2	11829448
Pubmed	Presence of regulatory sequences within intron 4 of human and murine c-myb genes.	MYC MYB	2.26e-05	2	166	2	7918623
Pubmed	ST7-mediated suppression of tumorigenicity of prostate cancer cells is characterized by remodeling of the extracellular matrix.	ST7 ST7L	2.26e-05	2	166	2	16474848
Pubmed	Up-regulation of fibronectin and tissue transglutaminase promotes cell invasion involving increased association with integrin and MMP expression in A431 cells.	FN1 TGM2	2.26e-05	2	166	2	21036738
Pubmed	Molecular Mechanisms of Synaptic Vesicle Priming by Munc13 and Munc18.	UNC13B UNC13A	2.26e-05	2	166	2	28772123
Pubmed	Cell-surface transglutaminase promotes fibronectin assembly via interaction with the gelatin-binding domain of fibronectin: a role in TGFbeta-dependent matrix deposition.	FN1 TGM2	2.26e-05	2	166	2	11686302
Pubmed	Munc13-1 C1 domain activation lowers the energy barrier for synaptic vesicle fusion.	UNC13B UNC13A	2.26e-05	2	166	2	17267576
Pubmed	Identification of new human cadherin genes using a combination of protein motif search and gene finding methods.	DCHS2 FAT4	2.26e-05	2	166	2	15003449
Pubmed	The low density lipoprotein receptor-related protein mediates fibronectin catabolism and inhibits fibronectin accumulation on cell surfaces.	FN1 LRP1	2.26e-05	2	166	2	11867643
Pubmed	Mycobacterium tuberculosis malate synthase is a laminin-binding adhesin.	FN1 LAMA1	2.26e-05	2	166	2	16677310
Pubmed	A fluorescent nanosensor paint detects dopamine release at axonal varicosities with high spatiotemporal resolution.	UNC13B UNC13A	2.26e-05	2	166	2	35613050
Pubmed	[Expression of c-myc and c-myb gene in leukemic bone marrow stromal cells and their correlation].	MYC MYB	2.26e-05	2	166	2	22739149
Pubmed	Membrane bridging by Munc13-1 is crucial for neurotransmitter release.	UNC13B UNC13A	2.26e-05	2	166	2	30816091
Pubmed	LRP1 is required for novobiocin-mediated fibronectin turnover.	FN1 LRP1	2.26e-05	2	166	2	30061663
Pubmed	A common molecular basis for membrane docking and functional priming of synaptic vesicles.	UNC13B UNC13A	2.26e-05	2	166	2	19558619
Pubmed	Phorbol esters modulate spontaneous and Ca2+-evoked transmitter release via acting on both Munc13 and protein kinase C.	UNC13B UNC13A	2.26e-05	2	166	2	18701688
Pubmed	Dissecting the interaction between transglutaminase 2 and fibronectin.	FN1 TGM2	2.26e-05	2	166	2	27394141
Pubmed	Cell-surface transglutaminase undergoes internalization and lysosomal degradation: an essential role for LRP1.	TGM2 LRP1	2.26e-05	2	166	2	17711877
Pubmed	Deregulated c-myb disrupts interleukin-6- or leukemia inhibitory factor-induced myeloid differentiation prior to c-myc: role in leukemogenesis.	MYC MYB	2.26e-05	2	166	2	1588953
Pubmed	Momordin Ic induces G0/1 phase arrest and apoptosis in colon cancer cells by suppressing SENP1/c-MYC signaling pathway.	MYC SENP1	2.26e-05	2	166	2	34049792
Pubmed	Desumoylation of homeodomain-interacting protein kinase 2 (HIPK2) through the cytoplasmic-nuclear shuttling of the SUMO-specific protease SENP1.	HIPK2 SENP1	2.26e-05	2	166	2	16253240
Pubmed	Beta phorbol ester- and diacylglycerol-induced augmentation of transmitter release is mediated by Munc13s and not by PKCs.	UNC13B UNC13A	2.26e-05	2	166	2	11792326
Pubmed	Remodeling of extracellular matrix by normal and tumor-associated fibroblasts promotes cervical cancer progression.	FN1 LAMA1	2.26e-05	2	166	2	25885552
Pubmed	The impact of Zearalenone on the meiotic progression and primordial follicle assembly during early oogenesis.	RAD51 DAZ4 DAZ1	2.95e-05	13	166	3	28552778
Pubmed	RAD51 is essential for spermatogenesis and male fertility in mice.	RAD51 DAZ4 DAZ1	2.95e-05	13	166	3	35292640
Pubmed	The reduction of oocytes and disruption of the meiotic prophase I in Fanconi anemia E-deficient mice.	RAD51 DAZ4 DAZ1	2.95e-05	13	166	3	35671285
Pubmed	Systematic protein-protein interaction mapping for clinically relevant human GPCRs.	FNBP1 PMPCB ASH1L GDPD2 TSHR CRYM KCNJ5 NGEF SLC9A7 FKBP8 HERC2 SETD3 GABBR1	3.29e-05	697	166	13	28298427
Pubmed	The first draft of the endostatin interaction network.	FN1 LAMA1 TGM2	3.74e-05	14	166	3	19542224
Pubmed	New interaction partners for Nek4.1 and Nek4.2 isoforms: from the DNA damage response to RNA splicing.	FAT4 ELMOD2 ZGRF1 SH2D3C CSMD3 ADAMTS6 TIMELESS OSMR HERC2 GOLGA5 AGTPBP1	3.91e-05	513	166	11	25798074
Pubmed	The p97/VCP segregase is essential for arsenic-induced degradation of PML and PML-RARA.	HIPK1 UGGT1 OAS3 THOC2 NUP205 USP2 SENP1 MORC3	4.03e-05	262	166	8	36880596
Pubmed	Robust phosphoproteomic profiling of tyrosine phosphorylation sites from human T cells using immobilized metal affinity chromatography and tandem mass spectrometry.	DOCK2 FNBP1 ZFYVE16 PDE8B GOLGA5 USP6NL	4.49e-05	133	166	6	15144186
Pubmed	Esrrb Complementation Rescues Development of Nanog-Null Germ Cells.	DAZ4 DAZ1 FGF5	4.66e-05	15	166	3	29320730
Pubmed	Proteomic analysis identifies transcriptional cofactors and homeobox transcription factors as TBX18 binding proteins.	PBX4 PBX1 PBX3	4.66e-05	15	166	3	30071041
Pubmed	The mammalian-membrane two-hybrid assay (MaMTH) for probing membrane-protein interactions in human cells.	ERBB4 SH2D3C STAP2 LRP1 SNX9 GABBR1	4.68e-05	134	166	6	24658140
Pubmed	Sex-specific chromatin remodelling safeguards transcription in germ cells.	RAD51 DAZ4 DAZ1	5.71e-05	16	166	3	34880491
Pubmed	The chromatin-remodeling subunit Baf200 promotes homology-directed DNA repair and regulates distinct chromatin-remodeling complexes.	RAD51 ARID2	6.77e-05	3	166	2	28381560
Pubmed	Identification of two new members of the CSMD gene family.	CSMD2 CSMD3	6.77e-05	3	166	2	12906867
Pubmed	The TALE homeodomain protein Pbx2 is not essential for development and long-term survival.	PBX1 PBX3	6.77e-05	3	166	2	15169896
Pubmed	Designation of enzyme activity of glycine-N-acyltransferase family genes and depression of glycine-N-acyltransferase in human hepatocellular carcinoma.	GLYAT GLYATL2	6.77e-05	3	166	2	22475485
Pubmed	Comparative genomics and diversifying selection of the clustered vertebrate protocadherin genes.	FAT3 FAT2	6.77e-05	3	166	2	15744052
Pubmed	A link between hepatic glucose production and peripheral energy metabolism via hepatokines.	FGF21 G6PC1	6.77e-05	3	166	2	25061558
Pubmed	MYB regulates the SUMO protease SENP1 and its novel interaction partner UXT, modulating MYB target genes and the SUMO landscape.	SENP1 MYB	6.77e-05	3	166	2	37468105
Pubmed	The extracellular matrix is a novel attribute of endothelial progenitors and of hypoxic mature endothelial cells.	FN1 LAMA1	6.77e-05	3	166	2	22919069
Pubmed	The interaction of angiocidin with tissue transglutaminase.	FN1 TGM2	6.77e-05	3	166	2	19931242
Pubmed	Phospholipase C beta3 deficiency leads to macrophage hypersensitivity to apoptotic induction and reduction of atherosclerosis in mice.	PLCB2 PLCB3	6.77e-05	3	166	2	18079968
Pubmed	HoxB8 requires its Pbx-interaction motif to block differentiation of primary myeloid progenitors and of most cell line models of myeloid differentiation.	PBX1 PBX3	6.77e-05	3	166	2	11571641
Pubmed	RUNX1 is required for oncogenic Myb and Myc enhancer activity in T-cell acute lymphoblastic leukemia.	MYC MYB	6.77e-05	3	166	2	28790107
Pubmed	Heterologously overexpressed, affinity-purified human meprin alpha is functionally active and cleaves components of the basement membrane in vitro.	LAMA1 MEP1A	6.77e-05	3	166	2	10620696
Pubmed	The relative role of PLCbeta and PI3Kgamma in platelet activation.	PLCB2 PLCB3	6.77e-05	3	166	2	15705797
Pubmed	Localization of the transglutaminase cross-linking site in SVS III, a novel glycoprotein secreted from mouse seminal vesicle.	SEMG1 TGM2	6.77e-05	3	166	2	11723121
Pubmed	Heterogeneous Presynaptic Distribution of Munc13 Isoforms at Retinal Synapses and Identification of an Unconventional Bipolar Cell Type with Dual Expression of Munc13 Isoforms: A Study Using Munc13-EXFP Knock-in Mice.	UNC13B UNC13A	6.77e-05	3	166	2	33105896
Pubmed	Common sites of viral integration in lymphomas arising in AKXD recombinant inbred mouse strains.	MYC MYB	6.77e-05	3	166	2	3505665
Pubmed	Regulation of phospholipase C-beta 3 activity by Na+/H+ exchanger regulatory factor 2.	PLCB2 PLCB3	6.77e-05	3	166	2	10748023
Pubmed	A novel pbx family member expressed during early zebrafish embryogenesis forms trimeric complexes with Meis3 and Hoxb1b.	PBX1 PBX3	6.77e-05	3	166	2	10679934
Pubmed	Inhibition of bromodomain and extra-terminal (BET) proteins increases NKG2D ligand MICA expression and sensitivity to NK cell-mediated cytotoxicity in multiple myeloma cells: role of cMYC-IRF4-miR-125b interplay.	MYC MICA	6.77e-05	3	166	2	27903272
GeneFamily	Cadherin related	DCHS2 FAT4 FAT3 FAT2	2.70e-06	17	108	4	24
GeneFamily	Phospholipases	PLCZ1 PLCB2 PLCB3 PLD1	1.13e-04	42	108	4	467
GeneFamily	Endogenous ligands\|C1q and TNF related	C1QL3 C1QL4 C1QL1	1.58e-04	18	108	3	1372
GeneFamily	Phospholipases\|C2 domain containing phospholipases	PLCZ1 PLCB2 PLCB3	1.87e-04	19	108	3	832
GeneFamily	UNC13 homologs	UNC13B UNC13A	2.10e-04	4	108	2	836
GeneFamily	TALE class homeoboxes and pseudogenes	PBX4 PBX1 PBX3	4.88e-04	26	108	3	526
GeneFamily	N(alpha)-acetyltransferase subunits\|GCN5 related N-acetyltransferases	NAA60 NAA25	2.24e-03	12	108	2	660
ToppCell	Primary_Motor_Cortex_(M1)-Neuronal-Glutamatergic_Excit\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	UNC13B MAN1A1 KALRN FAT3 SLC6A7 KIAA1549L FAM13A VPS13A NGEF CPNE4	2.95e-09	192	166	10	5c7e8b80b44d9ce55c797cdf8267ac5382e26cac
ToppCell	primary_auditory_cortex_(A1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	MAN1A1 KALRN FAT3 SLC6A7 FAM13A OTOGL NGEF CPNE4 MPPED2	3.68e-08	187	166	9	f18628ffc7ff7c762b8339ba8822cf0c3157f469
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	MAN1A1 KALRN FAT3 SLC6A7 FAM13A OTOGL NGEF CPNE4 MPPED2	3.86e-08	188	166	9	50c1b1d690f0e9443082f2adf4f1b8e9ce4cd337
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	UNC13B MAN1A1 KALRN FAT3 SLC6A7 FAM13A VPS13A NGEF CPNE4	4.04e-08	189	166	9	a75226616340045b581d08429d2e123e041dee55
ToppCell	Primary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	UNC13B KALRN FAT3 CSMD3 KIAA1549L VPS13A NGEF CPNE4 UNC13A	5.28e-08	195	166	9	2e1df01bf6e4e98e6cd9fb50926e34c5077b8666
ToppCell	facs-Lung-24m-Endothelial-capillary_endothelial-capillary_endothelial_cell-capillary_type_1_endothelial_cell\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	ELAPOR2 ERBB4 FAT3 NDST4 CSMD3 KIAA1549L OTOGL KLKB1	1.77e-07	162	166	8	bf886e22ff2a20353499004b53f25fb9e6574896
ToppCell	COVID-19_Mild-Neu_4\|World / 5 Neutrophil clusters in COVID-19 patients	EXPH5 C1QL3 FAT3 CCDC168 CSMD2 ANKRD30A RASL11B	4.29e-07	124	166	7	5ef9eb806fb2c8ee5aae0a75503d244b08ee10d4
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FAT4 KALRN FAT3 LAMA1 CSMD3 KCNA4 XIRP2 OTOGL	4.67e-07	184	166	8	2cbed6462fea2622871bb7e49b0df3d984239281
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FAT4 KALRN FAT3 LAMA1 CSMD3 KCNA4 XIRP2 OTOGL	4.67e-07	184	166	8	2b19a8c5f823e00812908b23e66bb4e563278aff
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FAT4 KALRN FAT3 LAMA1 CSMD3 KCNA4 XIRP2 OTOGL	4.67e-07	184	166	8	ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCell	PCW_05-06-Mesenchymal-Mesenchymal_fibroblastic-mes_immature_COL13A1^pos_fibro2_(5)\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	MYC FAT4 FN1 HIPK2 ADAMTS6 ZFP36L2 PBX3 MPPED2	5.07e-07	186	166	8	7def03dd856b765bd3f493288641981c4f7fd26e
ToppCell	Primary_Motor_Cortex_(M1)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	MAN1A1 KALRN FAT3 SLC6A7 FAM13A OTOGL NGEF CPNE4	5.07e-07	186	166	8	bdbe290f81106a53c8c30a92fbb385597c62b2ac
ToppCell	primary_auditory_cortex_(A1C)-Neuronal-Glutamatergic_Excit\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	UNC13B KALRN FAT3 SLC6A7 KIAA1549L VPS13A NGEF CPNE4	5.95e-07	190	166	8	49e09cdb843b3d889a06a811aa5affae68b25a75
ToppCell	Somatosensory_Cortex_(S1)-Neuronal-Glutamatergic_Excit\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	KALRN FAT3 SLC6A7 KIAA1549L FAM13A VPS13A NGEF CPNE4	5.95e-07	190	166	8	d594da827e3c16644952b9589cc12b947ce36279
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Ascending_Vasa_Recta_Endothelial_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	PALD1 FN1 KALRN SH2D3C NEDD4 TGM2 HEG1 PBX1	6.97e-07	194	166	8	fa6d51f36a3dae8763a595c20892987ed454c0f0
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Endothelial-blood_vessel_endothelial_cell_of_kidney\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	PALD1 FN1 KALRN SH2D3C TGM2 HEG1 ADAMTS6 PBX1	7.53e-07	196	166	8	22767bcf0095d9eb0cbed7cdc74e4d32d9357e1b
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	PALD1 FN1 KALRN SH2D3C NEDD4 HEG1 ADAMTS6 PBX1	7.53e-07	196	166	8	b8f89a50114932c08fc5daac4b549adfe9df8e66
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Endothelial\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	PALD1 FN1 KALRN SH2D3C TGM2 HEG1 ADAMTS6 PBX1	7.53e-07	196	166	8	adee900dcd16dbaba15c58bdcace09ba20214950
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Endothelial\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	PALD1 FN1 KALRN SH2D3C NEDD4 HEG1 ADAMTS6 PBX1	7.53e-07	196	166	8	d0ff1082898d2db47c88d2678466514e9e9193d3
ToppCell	Primary_Motor_Cortex_(M1)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_2-Exc_L3-5_RORB_CMAHP\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	CCDC168 SLC6A7 ARHGAP4 ADAMTS6 OTOGL CPNE4 MPPED2	3.70e-06	171	166	7	9d5cabd71a901a00eb16c4d151189296f1b3bf6f
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Descending_Vasa_Recta_Endothelial_Cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	FN1 KALRN SH2D3C HEG1 KIAA1549L ADAMTS6 TMEM184B	4.15e-06	174	166	7	3d4c05ea5719ca65e85d1f15198453034791087c
ToppCell	facs-Diaphragm-Limb_Muscle-24m-Endothelial\|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PLCZ1 STAP2 SNRK TGM2 CLIC5 UNC45B ARHGEF37	5.18e-06	180	166	7	f9b7d5eb7b6ea72253c89bdc351ad2b4a53f7d8e
ToppCell	facs-Diaphragm-Limb_Muscle-24m-Endothelial-endothelial_cell\|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PLCZ1 STAP2 SNRK TGM2 CLIC5 UNC45B ARHGEF37	5.18e-06	180	166	7	53db6032eda0e590ae7e01c9c3b472785ea6782f
ToppCell	facs-Diaphragm-Limb_Muscle-24m-Endothelial-nan\|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PLCZ1 STAP2 SNRK TGM2 CLIC5 UNC45B ARHGEF37	5.18e-06	180	166	7	28bc10b9d0e4430b952260014d8a6ff337860ac6
ToppCell	3'-Adult-SmallIntestine-Endothelial-blood_vessel_EC\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SH2D3C SNRK HEG1 ADAMTS6 ATOH8 PCDH19 GABBR1	5.78e-06	183	166	7	858682df5592c6856487487a7baabd6e60e63a38
ToppCell	3'-Adult-SmallIntestine-Endothelial\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SH2D3C SNRK HEG1 ADAMTS6 ATOH8 PCDH19 GABBR1	5.78e-06	183	166	7	f8212bf8a8b8312434ae030261c558c147f61747
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Neuronal-Glutamatergic_Excit\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	KALRN FAT3 SLC6A7 CRYM VPS13A NGEF CPNE4	6.42e-06	186	166	7	84ba666237c18189d7e7556bd92dd953af733c00
ToppCell	Somatosensory_Cortex_(S1)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	KALRN FAT3 SLC6A7 FAM13A NGEF CPNE4 MPPED2	7.13e-06	189	166	7	c3df0e3c50af8f1cfb4d790e668bd7f42b276992
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Ascending_Vasa_Recta_Endothelial_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	PALD1 FN1 KALRN SH2D3C NEDD4 HEG1 PBX1	7.64e-06	191	166	7	f663131a4810584c5854bd64ee7991a237b7707f
ToppCell	facs-Brain_Non-Myeloid-Cerebellum-3m-Endothelial-Endothelial_cell\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FN1 SNRK TGM2 HEG1 CLIC5 UNC45B OSMR	7.90e-06	192	166	7	9d53b42cdb537b30233cdfdc08052c8b13a1113f
ToppCell	facs-Brain_Non-Myeloid-Cerebellum-3m-Endothelial-endothelial_cell\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FN1 SNRK TGM2 HEG1 CLIC5 UNC45B OSMR	7.90e-06	192	166	7	042391162df2e3d0027688dd14163c4c6821afe0
ToppCell	facs-Brain_Non-Myeloid-Cortex-3m-Endothelial-Endothelial_cell\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	UNC13B FN1 SH2D3C HEG1 CLIC5 UNC45B OSMR	7.90e-06	192	166	7	9ae05db5bfb8b9d3935c0328e6f2d489d2b1ebfd
ToppCell	facs-Brain_Non-Myeloid-Cerebellum-3m-Endothelial\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FN1 SNRK TGM2 HEG1 CLIC5 UNC45B OSMR	7.90e-06	192	166	7	71b0bfee0461ff64cef35881db3959c517e9731b
ToppCell	facs-Brain_Non-Myeloid-Cortex-3m-Endothelial\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	UNC13B FN1 SH2D3C HEG1 CLIC5 UNC45B OSMR	7.90e-06	192	166	7	a116db7dec495e5a0ba9c7537057cd1e567d7885
ToppCell	facs-Brain_Non-Myeloid-Cortex-3m-Endothelial-endothelial_cell\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	UNC13B FN1 SH2D3C HEG1 CLIC5 UNC45B OSMR	7.90e-06	192	166	7	66defad13bd8e79319741e43ddb056841710b1d7
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	PALD1 FN1 KALRN SH2D3C NEDD4 HEG1 PBX1	8.18e-06	193	166	7	52e918884877b6659cdca0496390e440f73694a9
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	FN1 KALRN SH2D3C TGM2 HEG1 ADAMTS6 PBX1	8.18e-06	193	166	7	287e756d5fd3bd2931c168da24beaa0d02a350ae
ToppCell	PCW_07-8.5-Mesenchymal-Mesenchymal_fibroblastic-mes_adventitial_fibro_(10)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	DOCK2 FLNC CSMD3 ITIH3 PLD1 PBX1 KLHL4	8.18e-06	193	166	7	cd45118ced91b10baed3b1068d4673ec99824b86
ToppCell	facs-Aorta-Heart-3m-Endothelial\|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SH2D3C HIPK2 SNRK TGM2 HEG1 CLIC5 PBX1	8.74e-06	195	166	7	8493f2f60fc356af28b9c0e287d4cd8c8899c081
ToppCell	facs-Aorta-Heart-3m-Endothelial-aortic_endothelial_cell\|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SH2D3C HIPK2 SNRK TGM2 HEG1 CLIC5 PBX1	8.74e-06	195	166	7	5e5ca7bd94c9e924ed76f7ccac199be745d4c4eb
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	PALD1 FN1 KALRN SH2D3C NEDD4 HEG1 ADAMTS6	9.04e-06	196	166	7	145fcf73deba9638b391a1af6c39fa205dc9829f
ToppCell	facs-GAT-Fat-3m-Endothelial\|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SH2D3C STAP2 SNRK TGM2 CLIC5 UNC45B KLHL4	9.04e-06	196	166	7	b6cc1f466d45479764080d34b1daeb8243a5a9f3
ToppCell	facs-GAT-Fat-3m-Endothelial-endothelial_cell\|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SH2D3C STAP2 SNRK TGM2 CLIC5 UNC45B KLHL4	9.04e-06	196	166	7	ede6104cdfa4ee5287efcca9bbc36677cbf7a8d8
ToppCell	facs-GAT-Fat-3m-Endothelial-nan\|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SH2D3C STAP2 SNRK TGM2 CLIC5 UNC45B KLHL4	9.04e-06	196	166	7	039044ab28c53391c34d8226fb8cf78549e63ef4
ToppCell	Bronchial-NucSeq-Immune_Myeloid-Dendritic_cell\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	DOCK2 PALD1 GAPT KCNK13 SLC9A7 PLCB2 MCOLN2	9.35e-06	197	166	7	e0fc098bfb5a8b7824ae339f3adda30f78360d0b
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	PALD1 FN1 KALRN SH2D3C NEDD4 HEG1 ADAMTS6	9.66e-06	198	166	7	953630dbe3154b1b102b87de0feca2cbf124eabe
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	PALD1 FN1 KALRN SH2D3C NEDD4 HEG1 ADAMTS6	9.66e-06	198	166	7	8e45551224fbb30c0658ad47dd98335ecf165437
ToppCell	Tracheal-10x5prime-Endothelial-Endothelia_vascular-VE_systemic_arterial\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	FAT4 FN1 ARHGAP4 TGM2 HEG1 ADAMTS6 MPPED2	1.03e-05	200	166	7	5ec31c1be6bcc4124e1489d136570f3de33cc2e9
ToppCell	LPS_IL1RA_TNF-Endothelial-Endothelial-Activated_Alv_Cap\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	SH2D3C OAS3 SNRK NEDD4 TGM2 HEG1 DDX60L	1.03e-05	200	166	7	89821a264e872ed53e08e9d3609d5cc5c314503e
ToppCell	Neuronal-Excitatory\|Neuronal / cells hierarchy compared to all cells using T-Statistic	UNC13B KALRN FAT3 SLC6A7 FAM13A NGEF CPNE4	1.03e-05	200	166	7	4409065bc7aa995354c71e0f9d6f3726cf393d6b
ToppCell	Tracheal-10x5prime-Immune_Myeloid-Macrophage_other-Macro_AW_CX3CR1\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	DOCK2 PALD1 GAPT KCNK13 ARHGAP4 KCNJ5 PLCB2	1.03e-05	200	166	7	27f498bcd706d0751091662996795b5270e46f14
ToppCell	facs-Thymus-Thymus_Flowthrough-18m-Epithelial\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PNLIPRP2 FAT3 FGF21 ARHGEF37 IL23R GABBR1	2.85e-05	158	166	6	12661763d1c309106801cb710c04cd2b62d16cba
ToppCell	facs-Thymus-Thymus_Flowthrough-18m-Epithelial-TECs\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PNLIPRP2 FAT3 FGF21 ARHGEF37 IL23R GABBR1	2.85e-05	158	166	6	0792c39e6fc0745095af7812de2d50949540d60f
ToppCell	facs-Thymus-Thymus_Flowthrough-18m-Epithelial-epithelial_cell_of_thymus\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PNLIPRP2 FAT3 FGF21 ARHGEF37 IL23R GABBR1	2.85e-05	158	166	6	e7db50d6dfaf7280a73a0d5b5aa4f43ea2762d72
ToppCell	Posterior_cortex\|World / BrainAtlas - Mouse McCarroll V32	KALRN EXPH5 C1QL3 USP2 VPS13A FGF5	2.95e-05	159	166	6	18e9fe2efbe0bca7c3990f3b12b6f549e2c1263a
ToppCell	COVID-19-kidney-Technical/muscle_(Mes)\|kidney / Disease (COVID-19 only), tissue and cell type	FAT3 NDST4 CSMD2 CSMD3 XIRP2 CPNE4	2.95e-05	159	166	6	5335cbcdeaf2bbd0268bbfe0e45c8c0d288e640d
ToppCell	facs-Marrow-B-cells-24m-Lymphocytic-precursor_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FAT3 LAMA1 TECTB CRYM KIAA1549L HSD3B2	3.06e-05	160	166	6	c381ec6be8cf887861cc18f831a20db42f953fe1
ToppCell	facs-Marrow-Granulocytes-18m-Hematologic-megakaryocyte-erythroid_progenitor_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ERBB4 FN1 TMEM106A OTOGL KCNJ5 LRP1	3.06e-05	160	166	6	56e6f4b82b5dc41c45f9d253c2db314a6f702b84
ToppCell	facs-Marrow-B-cells-24m-Lymphocytic-pre_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FAT3 LAMA1 TECTB CRYM KIAA1549L HSD3B2	3.06e-05	160	166	6	25c8f3d2a6d14ff0ca0b965fce89d3ff22f40585
ToppCell	facs-Marrow-Granulocytes-18m-Hematologic-megakaryocyte-erythroid_progenitor_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ERBB4 FN1 TMEM106A OTOGL KCNJ5 LRP1	3.06e-05	160	166	6	bb1b966fb9e801db15e67d03e49db4609d6f935a
ToppCell	facs-Marrow-Granulocytes-18m-Hematologic\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ERBB4 FN1 TMEM106A OTOGL KCNJ5 LRP1	3.16e-05	161	166	6	60f433eab9d5531bdf6aa86b0265f20b866b904c
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell_of_renal_cortex-lymphatic_endothelial_cell_of_renal_cortex\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	PALD1 ELAPOR2 FLNC FN1 KALRN SH2D3C	3.28e-05	162	166	6	2ac02523348660e514d464f8f2434ee0c312d784
ToppCell	Posterior_cortex-Neuronal-Excitatory-eN1(Slc17a7)-eN1_1-Bcl6-Excitatory_Neuron.Slc17a7.Bcl6-Ptgfr_(Postsubiculum)\|Posterior_cortex / BrainAtlas - Mouse McCarroll V32	RAD51 CFAP47 ZGRF1 NDST4 ATXN2	3.31e-05	98	166	5	9865a9de11dea6db0b75dd04fee523cd2da44766
ToppCell	TCGA-Uterus-Primary_Tumor-Uterine_Carcinoma-Uterine_Carcinosarcoma-3\|TCGA-Uterus / Sample_Type by Project: Shred V9	ZFYVE16 GLYATL2 LYST FAT2 CRYM PCDH19	3.39e-05	163	166	6	d64dd39b077105c73e570ccef70f0e74a2c586ac
ToppCell	Children_(3_yrs)-Mesenchymal-airway_smooth_muscle_cell-D046\|Children_(3_yrs) / Lineage, Cell type, age group and donor	FAT4 FN1 SLC6A7 ADAMTS6 CT55 KLHL4	3.51e-05	164	166	6	e3983f655cdba308fb192182829f17bef99ce0ba
ToppCell	facs-Marrow-T_cells-18m-Lymphocytic-late_pro_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RAD51 PLCZ1 KALRN GDPD2 CENPI CLEC16A	3.63e-05	165	166	6	0edd56e8d14eaeced9882dd9206ea93e8f402e8d
ToppCell	facs-Marrow-T_cells-18m-Lymphocytic-late_pro-B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RAD51 PLCZ1 KALRN GDPD2 CENPI CLEC16A	3.63e-05	165	166	6	fa3aadfff6fb1e7f142db333c60c2cba02b17e6c
ToppCell	droplet-Lung-nan-21m-Lymphocytic-Proliferating_NK\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RAD51 CATSPERD ZGRF1 CENPI TIMELESS MYB	3.75e-05	166	166	6	21ba5fd755c0fb31ada42a1b5d60bede0153323d
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Afferent_/_Efferent_Arteriole_Endothelial_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	FAT4 SH2D3C GLYATL2 HEG1 ADAMTS6 KLHL4	3.75e-05	166	166	6	ec719368295133da2f7ff587c5329ed6db1dd56d
ToppCell	frontal_cortex-Neuronal-glutamatergic_neuron-L5_IT\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	EXPH5 C1QL3 FAT3 CRYM RASL11B CPNE4	3.88e-05	167	166	6	f1ce6e64ebede1f3ef36fe982f46919fd1f814dd
ToppCell	Somatosensory_Cortex_(S1)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_2-Exc_L3-5_RORB_CMAHP\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	CCDC168 ARHGAP4 ADAMTS6 OTOGL CPNE4 MPPED2	4.01e-05	168	166	6	1d58731a481ecac84c15affa84f8041dd67d944c
ToppCell	primary_auditory_cortex_(A1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_2-Exc_L3-5_RORB_CMAHP\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	CCDC168 ARHGAP4 ADAMTS6 OTOGL CPNE4 MPPED2	4.29e-05	170	166	6	49fc45d8a5c3ad89d1649fa46d7a285891379392
ToppCell	COVID-19-Heart-CM_+_Macrophage\|Heart / Disease (COVID-19 only), tissue and cell type	DOCK2 FLNC NRAP XIRP2 PLCB2 DDX60L	4.29e-05	170	166	6	4232fe937909f93d3736988c707b8f95ce993398
ToppCell	droplet-Skin-nan-18m-Epithelial-keratinocyte_stem_cell\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ELAPOR2 FLNC FAT4 KALRN FAM13A KLKB1	4.29e-05	170	166	6	10e0912dd0beab5d0bbe2bd49e477b5962687925
ToppCell	Control-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_2\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	DCHS2 FAT3 HECTD4 OTOGL LRP1 GABBR1	4.29e-05	170	166	6	5570c0e825bca77613bf0ebde620cf744fa1cb84
ToppCell	Healthy_donor-HSPC\|Healthy_donor / disease group, cell group and cell class (v2)	CATSPERD CRYM PABPC3 CENPI PBX1 MYB	4.58e-05	172	166	6	bc7549faadfc92c683c0e26bea380458706774b5
ToppCell	3'-Adult-SmallIntestine-Endothelial-blood_vessel_EC-Mature_venous_EC\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SH2D3C TGM2 HEG1 PCDH19 OSMR GABBR1	4.73e-05	173	166	6	b57d14e2c2368304cb903562d06ce8228f53857c
ToppCell	droplet-Liver-HEPATOCYTES-1m-Epithelial-Hepatocyte_(Periportal)\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FN1 ITIH3 NEDD4 FGF21 KLKB1 G6PC1	5.04e-05	175	166	6	5c38d4b6c03473d841e6203a7efaa6dcb2d59386
ToppCell	Control\|World / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ELAPOR2 SNRK CLIC5 PBX1 MPPED2 KLHL4	5.37e-05	177	166	6	b8ff6940e31b749776e81ae4f5bbd577dba9749c
ToppCell	CV-Severe-7\|Severe / Virus stimulation, Condition and Cluster	KALRN UGGT1 LYST ARID2 SIK2 IL23R	5.37e-05	177	166	6	82fdd6185b368f54f03de389427cbe3071d21a99
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Descending_Vasa_Recta_Endothelial_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	FAT4 FN1 SH2D3C HEG1 KIAA1549L ADAMTS6	5.54e-05	178	166	6	5f779a66aa42d1d8e8af17b4a08d5dcc733efd4c
ToppCell	Primary_Motor_Cortex_(M1)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_2\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	FAT3 CCDC168 SLC6A7 ADAMTS6 OTOGL CPNE4	5.71e-05	179	166	6	8766a5a066091879f521acfc612abf563ff78808
ToppCell	E18.5-Immune-Immune_Myeloid-Megakaryocyte/Platelet-Megakaryocyte/Platelet-Megakaryocyte/Platelet_mature\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	KALRN C1QL3 HECTD4 LYST KCNJ5 VPS13A	5.89e-05	180	166	6	4e9e8cde2919610c4ac0025b1c9819808048bc1d
ToppCell	E18.5-Immune-Immune_Myeloid-Megakaryocyte/Platelet\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	KALRN C1QL3 HECTD4 LYST KCNJ5 VPS13A	5.89e-05	180	166	6	ca2a35bfb67347e47f511589a3d0f763e6664634
ToppCell	E18.5-Immune-Immune_Myeloid-Megakaryocyte/Platelet-Megakaryocyte/Platelet\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	KALRN C1QL3 HECTD4 LYST KCNJ5 VPS13A	5.89e-05	180	166	6	466381bf93c3da6a2a241daadb68e9aad2964eae
ToppCell	frontal_cortex-Neuronal-glutamatergic_neuron\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	UNC13B EXPH5 C1QL3 CRYM NGEF RASL11B	6.08e-05	181	166	6	58f76bb9ea1518c2b629a0256a3f6595a9278152
ToppCell	facs-Thymus-Epithelium-3m\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	STAP2 TGM2 CLIC5 UNC45B ATOH8 OSMR	6.08e-05	181	166	6	bce56e12ab93693c9c04fa6aad8f2e1dff0c4d45
ToppCell	Severe-Lymphoid-pDC-\|Severe / Condition, Lineage, Cell class and cell subclass	PALD1 GAPT SLC9A7 MPPED2 MYB MCOLN2	6.08e-05	181	166	6	277ce4c49121da0990a5933b19d2c6af9bbe253e
ToppCell	Severe-Lymphoid-pDC\|Severe / Condition, Lineage, Cell class and cell subclass	PALD1 GAPT SLC9A7 MPPED2 MYB MCOLN2	6.08e-05	181	166	6	2caecb7c5dcdad46fd02b4ffb73cb613ce835187
ToppCell	Fetal_29-31_weeks-Mesenchymal-myofibroblast_cell-D062\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	FAT4 FN1 NDST4 ADAMTS6 RASL11B PBX3	6.08e-05	181	166	6	d7e04e0ca549eac6d9b1192b6578f9b54943d54f
ToppCell	PCW_05-06-Neuronal-Neuronal_SCP\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	ERBB4 CSMD2 C1QL1 CRYM KCNA4 SLC9A7	6.26e-05	182	166	6	b4fc5e4f5d8440a3c9ee0a6fd0da87b43cabc8c6
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	MAN1A1 FAT3 SLC6A7 CRYM OTOGL CPNE4	6.26e-05	182	166	6	14a117c5e50db31ee1b2cf4df4d133451fd6d55f
ToppCell	droplet-Spleen-nan-18m\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MAN1A1 ASH1L LYST IQGAP1 ZFP36L2 SNX9	6.26e-05	182	166	6	eeb5dfa4539e9ca5220f26bc2b65717ddcf13b6c
ToppCell	facs-Trachea-3m-Endothelial-endothelial_cell_of_trachea-tracheal_endothelial_cell-tracheal_endothelial_cell_l54\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	UNC13B SH2D3C STAP2 ITIH3 TGM2 KLHL4	6.26e-05	182	166	6	d22ab50b135482915687c70e6dad29bfe2bb2c68
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell_of_renal_cortex\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	PALD1 ELAPOR2 FLNC KALRN SH2D3C PLD1	6.26e-05	182	166	6	41b070085edba7a58b81c20aa4942d06f745acf8
ToppCell	pdx-Tumor_cells-T6\|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)	DOCK2 ZSWIM6 IQGAP1 KCNJ5 MPPED2 USP6NL	6.26e-05	182	166	6	7b24a4f712e1ae1525e8f1c8ec4e1fc43489cbee
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell_of_renal_cortex-lymphatic_endothelial_cell_of_renal_cortex\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	PALD1 ELAPOR2 FLNC KALRN SH2D3C PLD1	6.26e-05	182	166	6	5e9a67b2de0daa4fdc344b10a857d8a901ad810e
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Endothelial-lymphatic_endothelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	PALD1 ELAPOR2 FLNC KALRN SH2D3C PLD1	6.26e-05	182	166	6	b0fe042c71d6ab8c75abd7ba9d2de00b72d01c0c
ToppCell	droplet-Spleen-nan-18m-Lymphocytic\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MAN1A1 ASH1L LYST IQGAP1 ZFP36L2 SNX9	6.46e-05	183	166	6	28cbf909424f3be4491d49832f0aca0386560814
ToppCell	Control-APC-like-Dendritic_cells\|Control / group, cell type (main and fine annotations)	DOCK2 PALD1 FNBP1 KCNK13 SLC9A7 MCOLN2	6.46e-05	183	166	6	8f9c8e2436f18ea7c265b08e4e149e19cb513a16
Disease	Colorectal Carcinoma	MYC UNC13B FLNC FN1 KALRN LAMA1 ZBTB8B PBX4 CSMD3 TGM2 KCNA10 ZFP36L2 VPS13A LRP1 AGTPBP1 NLRP8	1.78e-06	702	162	16	C0009402
Disease	apolipoprotein B measurement	DCHS2 FN1 PMPCB PBX4 BABAM2 IQGAP1 KCNA4 ATXN2 FGF21 PCSK7 FGF5 PLCB3 MPPED2 KLKB1	1.90e-05	663	162	14	EFO_0004615
Disease	diastolic blood pressure, unipolar depression	HECTD4 NAA25 ATXN2 FGF5	2.15e-05	30	162	4	EFO_0003761, EFO_0006336
Disease	retinal vasculature measurement	ERBB4 HIPK2 USP2 KCNA4 XIRP2 ATXN2 MICA CPNE4 OSMR HERC2 MPPED2 UNC13A	3.08e-05	517	162	12	EFO_0010554
Disease	carbohydrate intake measurement	HECTD4 NAA25 ATXN2 FGF21	3.57e-05	34	162	4	EFO_0010811
Disease	low density lipoprotein cholesterol measurement, response to selective serotonin reuptake inhibitor	CSMD2 ADAMTS6 USP6NL	7.04e-05	15	162	3	EFO_0004611, EFO_0005658
Disease	intraocular pressure measurement	KALRN ST7 ST7L BABAM2 ZNF891 NEDD4 CLIC5 ADAMTS6 ZFP36L2 ATXN2 HERC2	1.25e-04	509	162	11	EFO_0004695
Disease	urate measurement	ERBB4 INTS7 ASH1L HECTD4 BABAM2 USP2 NAA25 FAM13A ATXN2 LRP1 FGF5 PLCB3 HSD3B2 MPPED2 G6PC1	1.31e-04	895	162	15	EFO_0004531
Disease	waist-hip ratio	RAD51 ERBB4 MAN1A1 FN1 HECTD4 NUP205 MEP1A FAM13A ADAMTS6 ATXN2 PDE8B PLCB3 PLD1 FKBP8 CPNE4 PBX1 MPPED2 CLEC16A	1.46e-04	1226	162	18	EFO_0004343
Disease	neutrophil percentage of leukocytes	PALD1 KALRN SH2D3C COPS3 IQGAP1 ZFP36L2 ATXN2 SLC9A7 MICA CLEC16A G6PC1 MYB	1.48e-04	610	162	12	EFO_0007990
Disease	hematocrit	KALRN ASH1L HECTD4 SENP1 KCNA4 FAM13A ATXN2 PDE8B ARID2 SLC9A7 FGF5 PLCB3 FKBP8 CPNE4 OSMR MYB	1.50e-04	1011	162	16	EFO_0004348
Disease	lymphocyte count	DOCK2 PALD1 FN1 KALRN EXPH5 PCDHGA1 HECTD4 PBX4 LYST IQGAP1 ARHGAP4 ZFP36L2 ATXN2 MICA DDX60L MORC3 PBX1 SETD3 CLEC16A MYB	1.62e-04	1464	162	20	EFO_0004587
Disease	Flushing	HECTD4 ATXN2	1.78e-04	4	162	2	HP_0031284
Disease	mean arterial pressure, alcohol drinking	HECTD4 ST7L NAA25 ATXN2 FGF5	2.11e-04	98	162	5	EFO_0004329, EFO_0006340
Disease	epilepsy (implicated_via_orthology)	UNC13B KALRN KCNA4 KCNA10 LRP1 UNC13A	2.91e-04	163	162	6	DOID:1826 (implicated_via_orthology)
Disease	Amyotrophic Lateral Sclerosis	ERBB4 PON3 ATXN2 UNC13A	2.95e-04	58	162	4	C0002736
Disease	Malignant neoplasm of breast	RAD51 ERBB4 FN1 KALRN NEDD4 TGM2 NAA25 KMT2D OTOGL UNC45B ANKRD30A SCP2 TIMELESS HERC2 G6PC1 NLRP8	2.95e-04	1074	162	16	C0006142
Disease	lymphocyte percentage of leukocytes	PALD1 PBX4 IQGAP1 ZFP36L2 ATXN2 SLC9A7 FCRLB MICA PLCB3 SETD3 G6PC1 MYB	3.24e-04	665	162	12	EFO_0007993
Disease	diastolic blood pressure, alcohol drinking	HECTD4 ST7L NAA25 ATXN2 FGF5	4.98e-04	118	162	5	EFO_0004329, EFO_0006336
Disease	asthma, Eczema, allergic rhinitis	MYC IQGAP1 ATXN2 SIK2 CLEC16A	5.58e-04	121	162	5	EFO_0005854, HP_0000964, MONDO_0004979
Disease	erythrocyte measurement	SENP1 KCNA4 ATXN2 PLD1 FKBP8 TERB2 MYB	5.68e-04	257	162	7	EFO_0005047
Disease	serum alanine aminotransferase measurement, response to combination chemotherapy	FNBP1 MYH13 CSMD2 CPNE4	6.39e-04	71	162	4	EFO_0004735, EFO_0007965
Disease	cardiomyopathy (implicated_via_orthology)	RAD51 ERBB4 MYH13 LRP1	6.39e-04	71	162	4	DOID:0050700 (implicated_via_orthology)
Disease	myocardial infarction	FN1 KALRN HECTD4 OAS3 NAA25 ATXN2 FGF5 PLCB2	7.35e-04	350	162	8	EFO_0000612
Disease	response to vaccine, cytokine measurement	DCHS2 MAN1A1 ITIH3 TIMELESS NLRP8	8.00e-04	131	162	5	EFO_0004645, EFO_0004873
Disease	Male sterility due to Y-chromosome deletions	DAZ4 DAZ1	8.21e-04	8	162	2	C2931163
Disease	Partial chromosome Y deletion	DAZ4 DAZ1	8.21e-04	8	162	2	C1507149
Disease	testis-expressed sequence 29 protein measurement	PON3 KLKB1	8.21e-04	8	162	2	EFO_0802125
Disease	coronary artery disease	FAT4 ERBB4 FN1 PNLIPRP2 HECTD4 NEDD4 NAA25 SENP1 CLIC5 ATXN2 LRP1 SIK2 FGF5 PLCB2 UNC13A GABBR1	9.22e-04	1194	162	16	EFO_0001645
Disease	coronary aneurysm	DOCK2 CSMD2 CPNE4	9.34e-04	35	162	3	EFO_1000881
Disease	Congenital adrenal hyperplasia	PDE8B HSD3B2	1.05e-03	9	162	2	C0001627
Disease	plasma renin activity measurement	XIRP2 KLKB1	1.05e-03	9	162	2	EFO_0006828
Disease	Graves ophthalmopathy (is_implicated_in)	TSHR IL23R	1.31e-03	10	162	2	DOID:0081120 (is_implicated_in)
Disease	transmembrane glycoprotein NMB measurement	NUP42 KLKB1	1.31e-03	10	162	2	EFO_0008303
Disease	eye color	MAN1A1 NUP205 KCNA4 HERC2	1.55e-03	90	162	4	EFO_0003949
Disease	beta-2 microglobulin measurement	ATXN2 MICA	1.59e-03	11	162	2	EFO_0005197
Disease	level of Ceramide (d40:1) in blood serum	PBX4 G6PC1	1.59e-03	11	162	2	OBA_2045185
Disease	serum gamma-glutamyl transferase measurement	GLYAT KALRN ASH1L HECTD4 CSMD3 BABAM2 FGF21 FBXO42 SLC9A7 SNX9 G6PC1 USP6NL GOLGA4	1.66e-03	914	162	13	EFO_0004532
Disease	Squamous cell carcinoma of esophagus	FAT4 FAT3 FAT2 KMT2D	1.89e-03	95	162	4	C0279626
Disease	alcohol consumption measurement, alcohol drinking	HECTD4 OAS3	1.91e-03	12	162	2	EFO_0004329, EFO_0007878
Disease	uric acid measurement	FAT4 ERBB4 INTS7 FAT3 HECTD4 TSHR USP2 NAA25 SIK2 FGF5	2.07e-03	610	162	10	EFO_0004761
Disease	hair colour measurement	ZFYVE16 LYST KMT2D CLIC5 FAM13A NGEF LRP1 FGF5 HERC2 MYB	2.20e-03	615	162	10	EFO_0007822
Disease	cholesteryl esters:total lipids ratio, high density lipoprotein cholesterol measurement	PON3 FAM13A ATXN2 FGF21 PCSK7 PLCB3	2.31e-03	243	162	6	EFO_0004612, EFO_0020944
Disease	gastroesophageal reflux disease	ERBB4 SNRK ATXN2 PBX3	2.36e-03	101	162	4	EFO_0003948
Disease	cholesteryl esters:total lipids ratio, intermediate density lipoprotein measurement	ATXN2 PCSK7 MICA PLCB3	2.54e-03	103	162	4	EFO_0008595, EFO_0020944
Disease	atopic eczema	DCHS2 IQGAP1 XIRP2 SIK2 CLEC16A GOLGA4	2.76e-03	252	162	6	EFO_0000274
Disease	African Burkitt's lymphoma	MYC PBX1	3.00e-03	15	162	2	C0343640
Disease	Ischemic stroke, tissue plasminogen activator measurement	HECTD4 ATXN2	3.00e-03	15	162	2	EFO_0004791, HP_0002140
Disease	Burkitt Leukemia	MYC PBX1	3.00e-03	15	162	2	C4721444
Disease	X-17654 measurement	PNLIPRP2 HEATR4	3.00e-03	15	162	2	EFO_0800784
Disease	Precursor T-Cell Lymphoblastic Leukemia-Lymphoma	MYC ZFP36L2 MYB	3.11e-03	53	162	3	C1961099
Disease	diastolic blood pressure, alcohol consumption measurement	HECTD4 ATXN2 FGF5	3.28e-03	54	162	3	EFO_0006336, EFO_0007878
Disease	coronary artery disease, factor VII measurement	PMPCB NAA25 ATXN2 FGF5	3.32e-03	111	162	4	EFO_0001645, EFO_0004619
Disease	Ischemic stroke, plasminogen activator inhibitor 1 measurement	HECTD4 ATXN2	3.42e-03	16	162	2	EFO_0004792, HP_0002140
Disease	resting metabolic rate measurement	RBM44 FGF21	3.42e-03	16	162	2	EFO_0008004
Disease	eosinophil count	NAA60 HECTD4 PBX4 THOC2 NUP205 NAA25 CLIC5 ZFP36L2 ATXN2 PDE8B SIK2 MICA PLCB3 PLD1 CLEC16A GABBR1 MYB	3.46e-03	1488	162	17	EFO_0004842
Disease	non-melanoma skin carcinoma	ZSWIM6 CSMD2 MICA HERC2 CLEC16A GABBR1	3.53e-03	265	162	6	EFO_0009260
Disease	factor XI measurement, coronary artery disease	MYH13 NAA25 ATXN2 FGF5	3.77e-03	115	162	4	EFO_0001645, EFO_0004694
Disease	dental caries	ZGRF1 CPNE4 MPPED2 KLKB1 NLRP8	3.80e-03	187	162	5	EFO_0003819
Disease	Graves disease, thyrotoxic periodic paralysis	DCHS2 MICA	3.86e-03	17	162	2	EFO_0004237, MONDO_0019201
Disease	factor XI measurement, Ischemic stroke	HECTD4 ATXN2	3.86e-03	17	162	2	EFO_0004694, HP_0002140
Disease	von Willebrand factor measurement, coronary artery disease	PMPCB HECTD4 ATXN2 FGF5	4.14e-03	118	162	4	EFO_0001645, EFO_0004629
Disease	HbA1c measurement	ASH1L NAA25 SENP1 KCNA4 ZFP36L2 ATXN2 VPS13A PLCB3 PLD1 MYB	4.25e-03	675	162	10	EFO_0004541
Disease	brain infarction	FGF5 SNX9	4.33e-03	18	162	2	EFO_0004277
Disease	alcohol use disorder (implicated_via_orthology)	UNC13B ERBB4 CLIC5 ARID2 UNC13A	4.53e-03	195	162	5	DOID:1574 (implicated_via_orthology)
Disease	anorectal malformation	CSMD2 NLRP8	4.82e-03	19	162	2	MONDO_0019938
Disease	glomerulonephritis (is_marker_for)	FN1 KLKB1	4.82e-03	19	162	2	DOID:2921 (is_marker_for)
Disease	factor VIII measurement, Ischemic stroke	HECTD4 ATXN2	4.82e-03	19	162	2	EFO_0004630, HP_0002140
Disease	oral squamous cell carcinoma (is_marker_for)	ERBB4 KMT2D ARID2	5.07e-03	63	162	3	DOID:0050866 (is_marker_for)
Disease	colorectal health	ST7 EXPH5 BABAM2 CLIC5 HERC2	5.15e-03	201	162	5	EFO_0008460

Protein segments in the cluster

Peptide	Gene	Start	Entry
LANINAYYAHTTAST	UNC13A	901	Q9UPW8
TTFQLEHNFNAKYTY	ERBB4	271	Q15303
HQSYDNLNYILSKEF	HSD3B2	261	P26439
LTYDYNFHSFNVEKQ	ASH1L	2256	Q9NR48
NLVYFSENYTSEAHQ	ELMOD2	176	Q8IZ81
QSSEDLHVFYSYQQL	CATSPERD	556	Q86XM0
NSTSNQLYLHFYSDI	CSMD2	1876	Q7Z408
LEYQDLTYSHQISSF	CSMD2	2071	Q7Z408
ETSLYFHSDYSQNKQ	CSMD3	2196	Q7Z407
LSNAYHELAQVYSTN	COPS3	256	Q9UNS2
YQEEAARHTYQALNS	ARHGEF37	386	A1IGU5
ADQNYDYASNSVVLH	C1QL3	206	Q5VWW1
QNYDYASNSVILHLD	C1QL4	191	Q86Z23
NSTNYTFYFEEEQRA	FAT4	1101	Q6V0I7
YNYQQHSVSDYLRQS	ARID2	131	Q68CP9
FSQLVYTSNDSYIVH	ANKRD30A	21	Q9BXX3
QNYDYASNSVILHLD	C1QL1	211	O75973
YYQFQAQETLEHNLA	DNHD1	3366	Q96M86
EYDLILNSDINSNHY	AGTPBP1	731	Q9UPW5
LYATQLNTHEYDFVS	CLIC5	46	Q9NZA1
SQEEFLTYLEHYQLT	ADAMTS6	31	Q9UKP5
VQAYSHYEIFTEQFS	CRYM	146	Q14894
AHLSIINEYLSQSYQ	IQGAP1	1246	P46940
QEYHSAEEQEYISNH	RBM44	186	Q6ZP01
DSQETYNFTLIAENY	OSMR	301	Q99650
YARAFNTDHQTQLLY	RAD51	191	Q06609
YQSLLTQVASEHFYF	INTS7	546	Q9NVH2
QSANDFFSYYDSHRQ	NUP205	1821	Q92621
AQLSENTYHVYHNTE	PALD1	216	Q9ULE6
VDYNTFHDTYETNTP	KCNJ5	346	P48544
IHEDNSTRSSQHFYY	MICA	121	Q29983
SYSSISHVIYNNHQD	ATOH8	191	Q96SQ7
SLTSSLNYFDYHQQT	PCDH19	806	Q8TAB3
YSFDSNYVNSRAHLI	PCDH19	876	Q8TAB3
ITQRFSHSACYYDAN	FBXO42	116	Q6P3S6
DEYSSNPTQAFTHYN	MPPED2	16	Q15777
EVVFDYLHATAYQNT	PMPCB	191	O75439
NKQATEILNEYFYSH	PBX1	241	P40424
ATEILNEYFYSHLSN	PBX3	246	P40426
INEDNIYISNSIYFS	CT55	121	Q8WUE5
SQYPAQFAHQTYISA	HIPK2	1161	Q9H2X6
LFEYSATDNYTLQIN	NEDD4	1026	P46934
NAQALASDHDYRTQY	NRAP	1371	Q86VF7
FYFHCQEVNQTTDQS	NLRP8	241	Q86W28
YLHVLTTNNTAINFY	NAA60	136	Q9H7X0
YQSATHEQTKAYEEQ	GOLGA4	806	Q13439
APAQYQHQFATQSYI	HIPK1	1171	Q86Z02
LQTSQIHYSYNEEKD	HERC2	1346	O95714
SFNIYNSHVRYIQNS	GABBR1	611	Q9UBS5
YSKNTDYTELHQQNT	GOLGA5	36	Q8TBA6
LTVFENYLYATNSDN	LRP1	416	Q07954
YFAISTGSLAQQYAH	ATXN2	1121	Q99700
TDDLDHYTNTYQIYS	GLYAT	66	Q6IB77
FLQDHSYKNQSYEVR	DDX60L	941	Q5H9U9
YNDDDIYLFNSSHSD	DCAF8L2	441	P0C7V8
SIYADLSHSNIYQSI	FSIP2	4866	Q5CZC0
AVAFNKHYQINDIYS	PCSK7	271	Q16549
DEEFTSLSTYQINHY	FAT2	696	Q9NYQ8
HNKQDFDYTNEYRLT	MORC3	356	Q14149
FQVIEANYHSSNAYH	PDE8B	601	O95263
YNDEDIYLFNSSHSD	DCAF8	406	Q5TAQ9
QRYLYTDDAQQTEAH	FGF21	46	Q9NSA1
QFYVDAINSRHVSAY	FLNC	1851	Q14315
LYENTGQSNFEEHIY	GAPT	111	Q8N292
GVSYQYALDLQTQHN	KALRN	341	O60229
ENKRYESYHSQNVYQ	EXPH5	411	Q8NEV8
ESYHSQNVYQRVSLN	EXPH5	416	Q8NEV8
QNHTYYDTFVIQTLE	GDPD2	361	Q9HCC8
SQNAHYESQGLYRFA	KCNK13	246	Q9HB14
NHSRDFQTAEVAYYS	KIAA1549L	511	Q6ZVL6
NNDYSYYHISEAQNV	MYB	241	P10242
FFHAQTERSNISSYD	HEG1	601	Q9ULI3
TFLSNYYRDHNVELS	NDST4	836	Q9H3R1
ATAQQQYDSDTSCHY	HECTD4	2196	Q9Y4D8
NYNTLFEVEYTENDH	FAM13A	226	O94988
FYHEKENQSLHYDFS	ELAPOR2	676	A8MWY0
HTYLNTVESYDAQRN	KLHL4	681	Q9C0H6
SSNYAYVNFQHTKDA	PABPC3	51	Q9H361
EYHNFLTSNNLQSYL	NUP42	161	O15504
IYQASVSESQLYNAH	DCHS2	2246	Q6V1P9
YFINSSHNTYLTAGQ	PLCB3	326	Q01970
FQENSYNTYASAIHR	FGF5	166	P12034
IVSNFNYFYHRETEN	KCNA10	456	Q16322
ATEVLNEYFYSHLNN	PBX4	221	Q9BYU1
HYQRADFVLAANSYD	FKBP8	231	Q14318
SLFHYSEYLVTAVNN	ICMT	101	O60725
SAVQVTTGYQFHVYN	DAZ1	696	Q9NQZ3
LEAYIQQHFSATLAY	DOCK2	696	Q92608
YHFTNSGQLYSQAQK	BABAM2	331	Q9NXR7
QFDIYSSQQSKYSHT	C5orf24	31	Q7Z6I8
SSILQKFNHEQHEYY	FNBP1	191	Q96RU3
NYEQDQKYSFCTDHT	FN1	391	P02751
FGIQSTHYLQVNYQD	G6PC1	11	P35575
YTVSHDFAINFNEDN	CPNE4	371	Q96A23
IVQDTYNSTDYFHID	FAT3	2326	Q8TDW7
YSFDHLYNTNDIIHT	HEATR4	91	Q86WZ0
DTNFTYVQQSEFYLE	IL23R	271	Q5VWK5
QQDYHARSYFQSHVV	C17orf98	46	A8MV24
YTGQITNFEYLTHLN	LYST	3136	Q99698
VYLLHESYDDVQQSF	MAN1A1	591	P33908
SYATQTFHKAEYRNN	KLKB1	151	P03952
SADYEEQKNSFHNYL	C2orf66	101	Q6UXQ4
SAVQVTTGYQFHVYN	DAZ4	531	Q86SG3
YEVQFTSQAQYINHN	CCDC168	311	Q8NDH2
YFHSSANYTVLQARA	FCRLB	146	Q6BAA4
NFSSKTYQEFNHYLT	CENPI	631	Q92674
YVNHDFAYTTFEKQQ	CFAP47	616	Q6ZTR5
DAYESIFFAINQYHQ	MCOLN2	126	Q8IZK6
NHLRSFEYYSSSVLN	PNLIPRP2	281	P54317
NYFLYVHDNDTLSLE	OTOGL	1281	Q3ZCN5
SSQVYVDLIHSYSNA	OAS3	906	Q9Y6K5
NDNSPVFHQDSYSAY	PCDHGA1	446	Q9Y5H4
VFHQDSYSAYIPENN	PCDHGA1	451	Q9Y5H4
VSVSENYNDVYSAFH	RASL11B	181	Q9BPW5
LSHSEQLVFQSYEYV	TMEM106A	231	Q96A25
EMNHFHSNRIYDYNS	SNX9	551	Q9Y5X1
LTIYFYNSNRDFQHV	STAP2	46	Q9UGK3
QDAIHNFSPAYQQYT	TMEM184B	351	Q9Y519
YRNYHATTEFLDISQ	PLD1	196	Q13393
LNDYFISSSHNTYLV	PLCZ1	161	Q86YW0
NFSPAYQHYTQQATH	TMEM184A	366	Q6ZMB5
DLTQNTYQHFYDGSE	ITIH3	486	Q06033
SFTNRNYDLDYDSVQ	MYC	6	P01106
SLNATSAAYVHYNIQ	LAMA1	1896	P25391
DQILSGYQHNFDTYD	MEP1A	181	Q16819
AADHFSVYITYVSNQ	NGEF	356	Q8N5V2
QYTYHVDANDHDQSR	SEMG1	66	P04279
NQEQLSHSVYSLSSY	SENP1	261	Q9P0U3
YLQSTQAIHDVFSQY	SETD3	196	Q86TU7
LILYSSNSANEVFHY	ST6GALNAC6	56	Q969X2
ESLQNKSYNHFAAIY	SIK2	316	Q9H0K1
HADKYSYTIDSNQEF	SLC26A10	301	Q8NG04
CTYHSTYLVNQAAFD	TECTB	121	Q96PL2
TYYDMNLSAQDHQTF	ST7	161	Q9NRC1
HSVNNPYSQFQDEYS	SCP2	191	P22307
ALETNRYNHITATYF	SNRK	316	Q9NRH2
ASVNAAVSNYYLHDV	ARHGAP4	251	P98171
QVFNNSPDESSYYRH	SEC23A	591	Q15436
LLTFASYNTFHQNIY	SLC6A7	306	Q99884
SYNTFHQNIYRDTFI	SLC6A7	311	Q99884
FSQLVYTNNDSYVIH	ANKRD30BL	21	A7E2S9
FYNEHTNDFALYTEA	CLEC16A	161	Q2KHT3
THISNNYGDNFLNYS	ZNF525	186	Q8N782
YNSAHDQNSNLLIEY	TGM2	301	P21980
ITSSRNTFAQYQYQH	XIRP2	91	A4UGR9
RTFHFIEQNLTNYYE	TIMELESS	406	Q9UNS1
HFQLQDYKAATNSYS	UNC45B	16	Q8IWX7
QQYYSLVHGDAFISN	TTLL8	306	A6PVC2
QQSLFHVLAAYSIYN	USP6NL	166	Q92738
SLVDQSQVSLYEYFH	VPS13A	2756	Q96RL7
SHDSSTYRDFQQALY	THOC2	36	Q8NI27
YQSLDYIEDNATVFH	TERB2	51	Q8NHR7
SHEDTLLQASYQFAY	ZBED8	86	Q8IZ13
TFQLSSERSYHIFYQ	MYH13	276	Q9UKX3
YYDMNLSAQDHQTFF	ST7L	181	Q8TDW4
QFYATRDHYFTNSLL	PON3	176	Q15166
ANINAYYAHTTASTN	UNC13B	826	O14795
YFINSSHNTYLTAGQ	PLCB2	321	Q00722
TNYCYHDDTENSLFD	ZSWIM6	541	Q9HCJ5
KSTENLYYQHQSENT	ZGRF1	306	Q86YA3
ESYTHIQYLFEQESF	SH2D3C	276	Q8N5H7
ITQAHYTYNNLSVES	SLC9A7	391	Q96T83
FASENTNHAVYNLYA	USP2	531	O75604
HNFAAVAAAAYYRSQ	ZFP36L2	381	P47974
HFQRNQTVQKEYTYS	ZNF891	256	A8MT65
NYVAQEVDDYHAFQT	UGGT1	556	Q9NYU2
QDYLQDVQNAYDSNH	ZFYVE16	26	Q7Z3T8
SKFQDTHNNAHYYVF	TSHR	341	P16473
THNNAHYYVFFEEQE	TSHR	346	P16473
QAVDLAYSNYHVKQF	ZBTB8B	266	Q8NAP8
DDQDHYTNTYHIFTK	GLYATL2	66	Q8WU03
SNFNYFYHRETENEE	KCNA4	561	P22459
QHSYTYNVSNLDVRQ	KMT2D	4891	O14686
HSNQKDTSEYIIQAY	NAA25	571	Q14CX7
FDNTTYKNLQHHDYS	NDUFV3	66	P56181