Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	protein-containing complex destabilizing activity	IQCA1 HSPA1A HSPA1B	8.47e-05	15	117	3	GO:0140776
GeneOntologyMolecularFunction	denatured protein binding	HSPA1A HSPA1B	1.02e-04	3	117	2	GO:0031249
GeneOntologyMolecularFunction	thyroxine 5'-deiodinase activity	DIO1 DIO2	1.02e-04	3	117	2	GO:0004800
GeneOntologyMolecularFunction	tRNA (cytidine-3-)-methyltransferase activity	METTL2A METTL2B	2.03e-04	4	117	2	GO:0052735
GeneOntologyMolecularFunction	sodium channel activity	ASIC3 NALCN ASIC4 CNGA1	2.44e-04	52	117	4	GO:0005272
GeneOntologyMolecularFunction	ATP-dependent activity	MYO1H DHX57 DNAH12 IQCA1 ABCE1 KIF13A HSPA1A HSPA1B DNAH8 XRCC6 DYNC1I1 SLC27A2	2.60e-04	614	117	12	GO:0140657
GeneOntologyMolecularFunction	death receptor agonist activity	HSPA1A HSPA1B	3.37e-04	5	117	2	GO:0038177
GeneOntologyMolecularFunction	ATP-dependent protein disaggregase activity	HSPA1A HSPA1B	5.03e-04	6	117	2	GO:0140545
GeneOntologyMolecularFunction	C3HC4-type RING finger domain binding	HSPA1A HSPA1B	5.03e-04	6	117	2	GO:0055131
GeneOntologyMolecularFunction	cytoskeletal motor activity	MYO1H DNAH12 KIF13A DNAH8 DYNC1I1	6.55e-04	118	117	5	GO:0003774
GeneOntologyMolecularFunction	microtubule motor activity	DNAH12 KIF13A DNAH8 DYNC1I1	7.62e-04	70	117	4	GO:0003777
GeneOntologyMolecularFunction	ATP hydrolysis activity	DHX57 DNAH12 IQCA1 ABCE1 KIF13A HSPA1A HSPA1B DNAH8 XRCC6	1.16e-03	441	117	9	GO:0016887
GeneOntologyMolecularFunction	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity	ALDH1A1 ALDH1B1	1.19e-03	9	117	2	GO:0043878
GeneOntologyMolecularFunction	tRNA (cytidine) methyltransferase activity	METTL2A METTL2B	1.49e-03	10	117	2	GO:0016427
GeneOntologyMolecularFunction	selenium binding	DIO1 DIO2	1.49e-03	10	117	2	GO:0008430
GeneOntologyBiologicalProcess	lysosomal transport	VPS11 ANKFY1 TGFBRAP1 KIF13A HSPA1A HSPA1B MGRN1	2.35e-05	151	116	7	GO:0007041
GeneOntologyBiologicalProcess	regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway	ERBIN HSPA1A HSPA1B	2.77e-05	11	116	3	GO:0070432
GeneOntologyBiologicalProcess	vacuolar transport	VPS11 ANKFY1 TGFBRAP1 KIF13A HSPA1A HSPA1B MGRN1	9.13e-05	187	116	7	GO:0007034
GeneOntologyBiologicalProcess	regulation of nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway	ERBIN HSPA1A HSPA1B	9.20e-05	16	116	3	GO:0070424
GeneOntologyBiologicalProcess	endosomal vesicle fusion	VPS11 ANKFY1 TGFBRAP1	9.20e-05	16	116	3	GO:0034058
GeneOntologyCellularComponent	dynein complex	DNAH12 CFAP70 DNAH8 DYNC1I1	2.22e-04	54	115	4	GO:0030286
GeneOntologyCellularComponent	axonemal dynein complex	DNAH12 CFAP70 DNAH8	3.42e-04	25	115	3	GO:0005858
GeneOntologyCellularComponent	plasma membrane bounded cell projection cytoplasm	CLXN EFCAB6 ARFGEF2 DNAH12 DST CFAP70 DNAH8 DYNC1I1	3.72e-04	317	115	8	GO:0032838
GeneOntologyCellularComponent	Pwp2p-containing subcomplex of 90S preribosome	WDR36 PWP2	4.44e-04	6	115	2	GO:0034388
GeneOntologyCellularComponent	CORVET complex	VPS11 TGFBRAP1	6.19e-04	7	115	2	GO:0033263
GeneOntologyCellularComponent	cytoplasmic region	CLXN EFCAB6 ARFGEF2 DNAH12 DST CFAP70 DNAH8 DYNC1I1	8.56e-04	360	115	8	GO:0099568
GeneOntologyCellularComponent	axoneme	CLXN EFCAB6 ARFGEF2 DNAH12 CFAP70 DNAH8	1.01e-03	207	115	6	GO:0005930
GeneOntologyCellularComponent	ciliary plasm	CLXN EFCAB6 ARFGEF2 DNAH12 CFAP70 DNAH8	1.03e-03	208	115	6	GO:0097014
GeneOntologyCellularComponent	COP9 signalosome	THEMIS HSPA1A HSPA1B	1.19e-03	38	115	3	GO:0008180
Domain	T4_deiodinase	DIO1 DIO2	1.18e-04	3	118	2	PF00837
Domain	T4_DEIODINASE	DIO1 DIO2	1.18e-04	3	118	2	PS01205
Domain	Iodothyronine_deiodinase_AS	DIO1 DIO2	1.18e-04	3	118	2	IPR008261
Domain	Iodothyronine_deiodinase	DIO1 DIO2	1.18e-04	3	118	2	IPR000643
Domain	MeTrfase	METTL2A METTL2B	2.36e-04	4	118	2	IPR026113
Domain	WD40/YVTN_repeat-like_dom	VPS11 WDR36 NBEAL1 SF3B3 WDR87 PWP2 IFT122 DYNC1I1 SEMA3E	2.78e-04	335	118	9	IPR015943
Domain	Methyltransf_12	METTL2A METTL2B	5.84e-04	6	118	2	IPR013217
Domain	Methyltransf_12	METTL2A METTL2B	5.84e-04	6	118	2	PF08242
Domain	WD40_repeat_dom	VPS11 WDR36 NBEAL1 SF3B3 WDR87 PWP2 IFT122 DYNC1I1	6.00e-04	297	118	8	IPR017986
Domain	Clathrin	VPS11 TGFBRAP1	8.14e-04	7	118	2	PF00637
Domain	CHCR	VPS11 TGFBRAP1	8.14e-04	7	118	2	PS50236
Domain	Clathrin_H-chain/VPS_repeat	VPS11 TGFBRAP1	1.08e-03	8	118	2	IPR000547
Domain	K_chnl_volt-dep_Kv1	KCNA2 KCNA10	1.08e-03	8	118	2	IPR003972
Domain	Na+channel_ASC_CS	ASIC3 ASIC4	1.08e-03	8	118	2	IPR020903
Domain	ASC	ASIC3 ASIC4	1.38e-03	9	118	2	PF00858
Domain	ASC	ASIC3 ASIC4	1.38e-03	9	118	2	PS01206
Domain	Na+channel_ASC	ASIC3 ASIC4	1.38e-03	9	118	2	IPR001873
Domain	ARM-type_fold	KPNA4 VPS11 NBEAL1 ARFGEF2 DOCK5 PPP2R1B MROH2B CAB39L	1.41e-03	339	118	8	IPR016024
Domain	GrpE_coiled_coil	DNAH8 CNGA1	2.51e-03	12	118	2	IPR013805
Domain	Dynein_heavy_chain_D4_dom	DNAH12 DNAH8	3.43e-03	14	118	2	IPR024317
Domain	Dynein_heavy_dom-2	DNAH12 DNAH8	3.43e-03	14	118	2	IPR013602
Domain	DHC_N2	DNAH12 DNAH8	3.43e-03	14	118	2	PF08393
Domain	ATPase_dyneun-rel_AAA	DNAH12 DNAH8	3.43e-03	14	118	2	IPR011704
Domain	AAA_8	DNAH12 DNAH8	3.43e-03	14	118	2	PF12780
Domain	AAA_5	DNAH12 DNAH8	3.43e-03	14	118	2	PF07728
Domain	CUB	CSMD3 TLL1 CSMD1	3.67e-03	49	118	3	PF00431
Domain	CUB	CSMD3 TLL1 CSMD1	3.88e-03	50	118	3	SM00042
Domain	DHC_fam	DNAH12 DNAH8	3.94e-03	15	118	2	IPR026983
Domain	Dynein_heavy	DNAH12 DNAH8	3.94e-03	15	118	2	PF03028
Domain	Dynein_heavy_dom	DNAH12 DNAH8	3.94e-03	15	118	2	IPR004273
Domain	-	CSMD3 TLL1 CSMD1	4.34e-03	52	118	3	2.60.120.290
Domain	Sushi	CD46 CSMD3 CSMD1	4.34e-03	52	118	3	PF00084
Domain	GRAM	TBC1D9 MTMR2	4.48e-03	16	118	2	SM00568
Domain	HSP70	HSPA1A HSPA1B	4.48e-03	16	118	2	PF00012
Domain	Ald_DH_CS_GLU	ALDH1A1 ALDH1B1	4.48e-03	16	118	2	IPR029510
Domain	CUB	CSMD3 TLL1 CSMD1	4.58e-03	53	118	3	PS01180
Domain	Quinoprotein_ADH-like_supfam	WDR36 WDR87 PWP2	4.58e-03	53	118	3	IPR011047
Domain	CCP	CD46 CSMD3 CSMD1	4.82e-03	54	118	3	SM00032
Domain	HSP70_2	HSPA1A HSPA1B	5.06e-03	17	118	2	PS00329
Domain	HSP70_1	HSPA1A HSPA1B	5.06e-03	17	118	2	PS00297
Domain	Ald_DH_CS_CYS	ALDH1A1 ALDH1B1	5.06e-03	17	118	2	IPR016160
Domain	HSP70_3	HSPA1A HSPA1B	5.06e-03	17	118	2	PS01036
Domain	-	VPS11 WDR36 NBEAL1 WDR87 IFT122 DYNC1I1 SEMA3E	5.25e-03	333	118	7	2.130.10.10
Domain	SUSHI	CD46 CSMD3 CSMD1	5.34e-03	56	118	3	PS50923
Domain	Sushi_SCR_CCP_dom	CD46 CSMD3 CSMD1	5.61e-03	57	118	3	IPR000436
Domain	CUB_dom	CSMD3 TLL1 CSMD1	5.61e-03	57	118	3	IPR000859
Domain	Channel_four-helix_dom	KCNA2 KCNA10 NALCN	5.61e-03	57	118	3	IPR027359
Domain	-	KCNA2 KCNA10 NALCN	5.61e-03	57	118	3	1.20.120.350
Domain	ALDEHYDE_DEHYDR_CYS	ALDH1A1 ALDH1B1	5.67e-03	18	118	2	PS00070
Domain	ALDEHYDE_DEHYDR_GLU	ALDH1A1 ALDH1B1	5.67e-03	18	118	2	PS00687
Domain	Hsp_70_fam	HSPA1A HSPA1B	5.67e-03	18	118	2	IPR013126
Domain	Ion_trans_dom	KCNA2 KCNA10 NALCN CNGA1	5.93e-03	114	118	4	IPR005821
Domain	Ion_trans	KCNA2 KCNA10 NALCN CNGA1	5.93e-03	114	118	4	PF00520
Domain	WD40	WDR36 NBEAL1 WDR87 PWP2 IFT122 DYNC1I1	6.08e-03	259	118	6	PF00400
Domain	-	ALDH1A1 ALDH1B1	6.31e-03	19	118	2	3.40.605.10
Domain	Aldedh	ALDH1A1 ALDH1B1	6.31e-03	19	118	2	PF00171
Domain	Ald_DH_C	ALDH1A1 ALDH1B1	6.31e-03	19	118	2	IPR016163
Domain	Ald_DH_N	ALDH1A1 ALDH1B1	6.31e-03	19	118	2	IPR016162
Domain	Ald_DH/histidinol_DH	ALDH1A1 ALDH1B1	6.31e-03	19	118	2	IPR016161
Domain	Aldehyde_DH_dom	ALDH1A1 ALDH1B1	6.31e-03	19	118	2	IPR015590
Domain	-	ALDH1A1 ALDH1B1	6.31e-03	19	118	2	3.40.309.10
Pubmed	Analysis of HSF4 binding regions reveals its necessity for gene regulation during development and heat shock response in mouse lenses.	CSMD3 XYLT1 HSPA1A HSPA1B	1.36e-06	24	120	4	18755693
Pubmed	A protein interaction network for Ecm29 links the 26 S proteasome to molecular motors and endosomal components.	VPS11 RNF217 DST HSPA1A DYNC1I1	2.11e-06	60	120	5	20682791
Pubmed	Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.	WDR36 ERH DSC2 PON2 KIAA1549 PSMD8 NIBAN2 ERBIN KIAA0753 SF3B3 SNX6 BUB1B PWP2 IFT122 CRYBG3 HSPA1A HSPA1B XRCC6	3.56e-06	1487	120	18	33957083
Pubmed	BioID reveals an ATG9A interaction with ATG13-ATG101 in the degradation of p62/SQSTM1-ubiquitin clusters.	NBEAL1 VPS50 AP4S1 POLR3B DST SNX6 ABCE1 TGFBRAP1	7.01e-06	285	120	8	34369648
Pubmed	A high-throughput approach for measuring temporal changes in the interactome.	KPNA4 ANKFY1 UBE4B ARFGEF2 PSMD8 NIBAN2 UBR7 TERF2IP PPP2R1B SNX6 ABCE1 BUB1B MTMR2 ALDH1B1 KIF13A HSPA1A XRCC6	1.08e-05	1455	120	17	22863883
Pubmed	A CASPR1-ATP1B3 protein interaction modulates plasma membrane localization of Na+/K+-ATPase in brain microvascular endothelial cells.	HSPA1A HSPA1B XRCC6	1.12e-05	13	120	3	30792309
Pubmed	Interaction of U-box-type ubiquitin-protein ligases (E3s) with molecular chaperones.	UBE4B HSPA1A HSPA1B	1.12e-05	13	120	3	15189447
Pubmed	Exercise induces hepatosplanchnic release of heat shock protein 72 in humans.	HSPA1A HSPA1B	1.18e-05	2	120	2	12411538
Pubmed	Molecular cloning and analysis of DNA complementary to three mouse Mr = 68,000 heat shock protein mRNAs.	HSPA1A HSPA1B	1.18e-05	2	120	2	2868009
Pubmed	Genetic manipulation of cardiac Hsp72 levels does not alter substrate metabolism but reveals insights into high-fat feeding-induced cardiac insulin resistance.	HSPA1A HSPA1B	1.18e-05	2	120	2	25618331
Pubmed	Up-regulation of inducible heat shock protein-70 expression in multiple sclerosis patients.	HSPA1A HSPA1B	1.18e-05	2	120	2	24328534
Pubmed	In vitro transcription of a human hsp 70 heat shock gene by extracts prepared from heat-shocked and non-heat-shocked human cells.	HSPA1A HSPA1B	1.18e-05	2	120	2	3786141
Pubmed	Extracellular heat shock protein 72 is a marker of the stress protein response in acute lung injury.	HSPA1A HSPA1B	1.18e-05	2	120	2	16679378
Pubmed	Inducible 70 kDa heat shock proteins protect embryos from teratogen-induced exencephaly: Analysis using Hspa1a/a1b knockout mice.	HSPA1A HSPA1B	1.18e-05	2	120	2	19639652
Pubmed	Type 1 and type 2 iodothyronine deiodinases in the thyroid gland of patients with huge goitrous Hashimoto's thyroiditis.	DIO1 DIO2	1.18e-05	2	120	2	30737677
Pubmed	Effect of mutation of amino acids 246-251 (KRKHKK) in HSP72 on protein synthesis and recovery from hypoxic injury.	HSPA1A HSPA1B	1.18e-05	2	120	2	16100242
Pubmed	Role of the C-terminal region of mouse inducible Hsp72 in the recognition of peptide substrate for chaperone activity.	HSPA1A HSPA1B	1.18e-05	2	120	2	15498567
Pubmed	Biological activity of truncated C-terminus human heat shock protein 72.	HSPA1A HSPA1B	1.18e-05	2	120	2	21094186
Pubmed	Characterization of the binding between a 70-kDa heat shock protein, HspA1A, and phosphoinositides.	HSPA1A HSPA1B	1.18e-05	2	120	2	26923070
Pubmed	Positive correlation between type 1 and 2 iodothyronine deiodinases activities in human goiters.	DIO1 DIO2	1.18e-05	2	120	2	22207295
Pubmed	Surface expression of HSP72 by LPS-stimulated neutrophils facilitates gammadeltaT cell-mediated killing.	HSPA1A HSPA1B	1.18e-05	2	120	2	16482515
Pubmed	Geranylgeranylaceton induces heat shock protein 72 in skeletal muscle cells.	HSPA1A HSPA1B	1.18e-05	2	120	2	17482577
Pubmed	Effect of hyaluronan oligosaccharides on the expression of heat shock protein 72.	HSPA1A HSPA1B	1.18e-05	2	120	2	11864979
Pubmed	Structure and expression of an inducible HSP70-encoding gene from Mus musculus.	HSPA1A HSPA1B	1.18e-05	2	120	2	8076831
Pubmed	The 70 kDa heat shock protein protects against experimental traumatic brain injury.	HSPA1A HSPA1B	1.18e-05	2	120	2	23816752
Pubmed	Hippocampal 72-kDa heat shock protein expression varies according to mice learning performance independently from chronic exposure to stress.	HSPA1A HSPA1B	1.18e-05	2	120	2	15719414
Pubmed	Hsp70 protects from stroke in atrial fibrillation patients by preventing thrombosis without increased bleeding risk.	HSPA1A HSPA1B	1.18e-05	2	120	2	26976620
Pubmed	Targeting membrane heat-shock protein 70 (Hsp70) on tumors by cmHsp70.1 antibody.	HSPA1A HSPA1B	1.18e-05	2	120	2	21187371
Pubmed	Inducible expression of an hsp68-lacZ hybrid gene in transgenic mice.	DST HSPA1B	1.18e-05	2	120	2	2557196
Pubmed	Radiation therapy induces circulating serum Hsp72 in patients with prostate cancer.	HSPA1A HSPA1B	1.18e-05	2	120	2	20430459
Pubmed	Astrocyte targeted overexpression of Hsp72 or SOD2 reduces neuronal vulnerability to forebrain ischemia.	HSPA1A HSPA1B	1.18e-05	2	120	2	20235222
Pubmed	Genetic determinants of HSP70 gene expression following heat shock.	HSPA1A HSPA1B	1.18e-05	2	120	2	20876613
Pubmed	The C-terminal BAG domain of BAG5 induces conformational changes of the Hsp70 nucleotide-binding domain for ADP-ATP exchange.	HSPA1A HSPA1B	1.18e-05	2	120	2	20223214
Pubmed	Structure of a new crystal form of human Hsp70 ATPase domain.	HSPA1A HSPA1B	1.18e-05	2	120	2	10216320
Pubmed	Membrane-associated Hsp72 from tumor-derived exosomes mediates STAT3-dependent immunosuppressive function of mouse and human myeloid-derived suppressor cells.	HSPA1A HSPA1B	1.18e-05	2	120	2	20093776
Pubmed	Bacterial infection elicits heat shock protein 72 release from pleural mesothelial cells.	HSPA1A HSPA1B	1.18e-05	2	120	2	23704948
Pubmed	Optimal bone strength and mineralization requires the type 2 iodothyronine deiodinase in osteoblasts.	DIO1 DIO2	1.18e-05	2	120	2	20368437
Pubmed	The association of polymorphisms in the type 1 and 2 deiodinase genes with circulating thyroid hormone parameters and atrophy of the medial temporal lobe.	DIO1 DIO2	1.18e-05	2	120	2	17105838
Pubmed	Effects of voluntary exercise and genetic selection for high activity levels on HSP72 expression in house mice.	HSPA1A HSPA1B	1.18e-05	2	120	2	14672969
Pubmed	Structure and expression of the human gene encoding major heat shock protein HSP70.	HSPA1A HSPA1B	1.18e-05	2	120	2	2858050
Pubmed	Nuclear heat shock protein 72 as a negative regulator of oxidative stress (hydrogen peroxide)-induced HMGB1 cytoplasmic translocation and release.	HSPA1A HSPA1B	1.18e-05	2	120	2	17513788
Pubmed	IL-6 activates HSP72 gene expression in human skeletal muscle.	HSPA1A HSPA1B	1.18e-05	2	120	2	12207910
Pubmed	Genetic Modulation of HSPA1A Accelerates Kindling Progression and Exerts Pro-convulsant Effects.	HSPA1A HSPA1B	1.18e-05	2	120	2	29964156
Pubmed	Inducing heat shock protein 70 expression provides a robust antithrombotic effect with minimal bleeding risk.	HSPA1A HSPA1B	1.18e-05	2	120	2	28837204
Pubmed	Molecular cloning of sequences encoding the human heat-shock proteins and their expression during hyperthermia.	HSPA1A HSPA1B	1.18e-05	2	120	2	3019832
Pubmed	Sequence analysis of HSPA1A and HSPA1B in a multi-ethnic study population.	HSPA1A HSPA1B	1.18e-05	2	120	2	17364813
Pubmed	Activating HSP72 in rodent skeletal muscle increases mitochondrial number and oxidative capacity and decreases insulin resistance.	HSPA1A HSPA1B	1.18e-05	2	120	2	24430435
Pubmed	Effects of heat shock protein 72 (Hsp72) on evolution of astrocyte activation following stroke in the mouse.	HSPA1A HSPA1B	1.18e-05	2	120	2	22940431
Pubmed	Concurrent action of purifying selection and gene conversion results in extreme conservation of the major stress-inducible Hsp70 genes in mammals.	HSPA1A HSPA1B	1.18e-05	2	120	2	29572464
Pubmed	Protective effect of heat shock proteins 70.1 and 70.3 on retinal photic injury after systemic hyperthermia.	HSPA1A HSPA1B	1.18e-05	2	120	2	15988927
Pubmed	Expression of 5'-deiodinase enzymes in normal pituitaries and in various human pituitary adenomas.	DIO1 DIO2	1.18e-05	2	120	2	12153750
Pubmed	The role of heat shock protein 70 in mediating age-dependent mortality in sepsis.	HSPA1A HSPA1B	1.18e-05	2	120	2	21296977
Pubmed	Adult mice lacking the type 2 iodothyronine deiodinase have increased subchondral bone but normal articular cartilage.	DIO1 DIO2	1.18e-05	2	120	2	25549200
Pubmed	The anti-inflammatory effects of heat shock protein 72 involve inhibition of high-mobility-group box 1 release and proinflammatory function in macrophages.	HSPA1A HSPA1B	1.18e-05	2	120	2	17617616
Pubmed	Hsp70 (HSPA1) Lysine Methylation Status as a Potential Prognostic Factor in Metastatic High-Grade Serous Carcinoma.	HSPA1A HSPA1B	1.18e-05	2	120	2	26448330
Pubmed	Downregulation of Heat Shock Protein 70 Impairs Osteogenic and Chondrogenic Differentiation in Human Mesenchymal Stem Cells.	HSPA1A HSPA1B	1.18e-05	2	120	2	29323151
Pubmed	HSP70.1 and -70.3 are required for late-phase protection induced by ischemic preconditioning of mouse hearts.	HSPA1A HSPA1B	1.18e-05	2	120	2	12714332
Pubmed	Inflammation-induced, 3'UTR-dependent translational inhibition of Hsp70 mRNA impairs intestinal homeostasis.	HSPA1A HSPA1B	1.18e-05	2	120	2	19299581
Pubmed	Insights into regulation and function of the major stress-induced hsp70 molecular chaperone in vivo: analysis of mice with targeted gene disruption of the hsp70.1 or hsp70.3 gene.	HSPA1A HSPA1B	1.18e-05	2	120	2	11713291
Pubmed	Heat shock protein 72 (Hsp72) improves long term recovery after focal cerebral ischemia in mice.	HSPA1A HSPA1B	1.18e-05	2	120	2	21108992
Pubmed	The septic shock associated HSPA1B1267 polymorphism influences production of HSPA1A and HSPA1B.	HSPA1A HSPA1B	1.18e-05	2	120	2	15232679
Pubmed	Prion disease is accelerated in mice lacking stress-induced heat shock protein 70 (HSP70).	HSPA1A HSPA1B	1.18e-05	2	120	2	31320473
Pubmed	Heat shock protein 72 supports extracellular matrix production in metastatic mammary tumors.	HSPA1A HSPA1B	1.18e-05	2	120	2	38703814
Pubmed	Structure and function of Hip, an attenuator of the Hsp70 chaperone cycle.	HSPA1A HSPA1B	1.18e-05	2	120	2	23812373
Pubmed	Loss of Hsp70 exacerbates pathogenesis but not levels of fibrillar aggregates in a mouse model of Huntington's disease.	HSPA1A HSPA1B	1.18e-05	2	120	2	19605647
Pubmed	hsp72, a host determinant of measles virus neurovirulence.	HSPA1A HSPA1B	1.18e-05	2	120	2	16971451
Pubmed	Human immunodeficiency virus-1 Nef suppresses Hsp70-mediated Tat activation.	HSPA1A HSPA1B	1.18e-05	2	120	2	21970979
Pubmed	Induction of heat shock protein 70 inhibits ischemic renal injury.	HSPA1A HSPA1B	1.18e-05	2	120	2	21270764
Pubmed	[Relationship between heat stress protein 70 gene polymorphisms and the risk of acute mountain sickness].	HSPA1A HSPA1B	1.18e-05	2	120	2	15748471
Pubmed	Heat shock protein 70 upregulation by geldanamycin reduces brain injury in a mouse model of intracerebral hemorrhage.	HSPA1A HSPA1B	1.18e-05	2	120	2	20849898
Pubmed	Heat shock protein 70 promotes lipogenesis in HepG2 cells.	HSPA1A HSPA1B	1.18e-05	2	120	2	29631603
Pubmed	Coordinated post-transcriptional regulation of Hsp70.3 gene expression by microRNA and alternative polyadenylation.	HSPA1A HSPA1B	1.18e-05	2	120	2	21757701
Pubmed	Inducible heat shock protein 70 prevents multifocal flat dysplastic lesions and invasive tumors in an inflammatory model of colon cancer.	HSPA1A HSPA1B	1.18e-05	2	120	2	19005184
Pubmed	Life without thyroxine to 3,5,3'-triiodothyronine conversion: studies in mice devoid of the 5'-deiodinases.	DIO1 DIO2	1.18e-05	2	120	2	19196796
Pubmed	Role of membrane Hsp70 in radiation sensitivity of tumor cells.	HSPA1A HSPA1B	1.18e-05	2	120	2	26197988
Pubmed	Effects of HSP70.1/3 gene knockout on acute respiratory distress syndrome and the inflammatory response following sepsis.	HSPA1A HSPA1B	1.18e-05	2	120	2	16361353
Pubmed	Glutamine's protection against sepsis and lung injury is dependent on heat shock protein 70 expression.	HSPA1A HSPA1B	1.18e-05	2	120	2	17234954
Pubmed	Hsp72 overexpression accelerates the recovery from caerulein-induced pancreatitis.	HSPA1A HSPA1B	1.18e-05	2	120	2	22792201
Pubmed	Ku70 and non-homologous end joining protect testicular cells from DNA damage.	TERF2IP XRCC6	1.18e-05	2	120	2	23857907
Pubmed	Association between phenols and thyroid hormones: The role of iodothyronine deiodinase genes.	DIO1 DIO2	1.18e-05	2	120	2	35964788
Pubmed	Conserved features of eukaryotic hsp70 genes revealed by comparison with the nucleotide sequence of human hsp70.	HSPA1A HSPA1B	1.18e-05	2	120	2	3931075
Pubmed	Inhibition of hsp70-1 and hsp70-3 expression disrupts preimplantation embryogenesis and heightens embryo sensitivity to arsenic.	HSPA1A HSPA1B	1.18e-05	2	120	2	9820195
Pubmed	Surface expression of a C-terminal alpha-helix region in heat shock protein 72 on murine LL/2 lung carcinoma can be recognized by innate immune sentinels.	HSPA1A HSPA1B	1.18e-05	2	120	2	19157555
Pubmed	Tumor necrosis factor alpha and inflammation disrupt the polarity complex in intestinal epithelial cells by a posttranslational mechanism.	HSPA1A HSPA1B	1.18e-05	2	120	2	21135124
Pubmed	Heat Shock Protein 70 Is Involved in the Efficiency of Preconditioning with Cyclosporine A in Renal Ischemia Reperfusion Injury by Modulating Mitochondrial Functions.	HSPA1A HSPA1B	1.18e-05	2	120	2	37298493
Pubmed	Heat-shock protein 70 genes and human longevity: a view from Denmark.	HSPA1A HSPA1B	1.18e-05	2	120	2	16804002
Pubmed	Deletion of the inducible 70-kDa heat shock protein genes in mice impairs cardiac contractile function and calcium handling associated with hypertrophy.	HSPA1A HSPA1B	1.18e-05	2	120	2	16735677
Pubmed	The role of type 1 and type 2 5'-deiodinase in the pathophysiology of the 3,5,3'-triiodothyronine toxicosis of McCune-Albright syndrome.	DIO1 DIO2	1.18e-05	2	120	2	18349068
Pubmed	HspA1A, a 70-kDa heat shock protein, differentially interacts with anionic lipids.	HSPA1A HSPA1B	1.18e-05	2	120	2	26476215
Pubmed	Impact of hepatic HSP72 on insulin signaling.	HSPA1A HSPA1B	1.18e-05	2	120	2	30532989
Pubmed	Cloning and in vitro expression of the human selenoprotein, type I iodothyronine deiodinase.	DIO1 DIO2	1.18e-05	2	120	2	1400883
Pubmed	Functional region of mouse heat shock protein 72 for its binding to lymphoid neoplastic P388D1 cells.	HSPA1A HSPA1B	1.18e-05	2	120	2	17126904
Pubmed	Syntenic conservation of HSP70 genes in cattle and humans.	HSPA1A HSPA1B	1.18e-05	2	120	2	1478667
Pubmed	Heat-shock protein 70 can replace viral protein R of HIV-1 during nuclear import of the viral preintegration complex.	KPNA4 HSPA1A HSPA1B	1.77e-05	15	120	3	10964507
Pubmed	Heat shock protein 70 inhibits alpha-synuclein fibril formation via preferential binding to prefibrillar species.	HSPA1A HSPA1B	3.53e-05	3	120	2	15671022
Pubmed	Chromosomal location of human genes encoding major heat-shock protein HSP70.	HSPA1A HSPA1B	3.53e-05	3	120	2	3470951
Pubmed	Genomic instability and enhanced radiosensitivity in Hsp70.1- and Hsp70.3-deficient mice.	HSPA1A HSPA1B	3.53e-05	3	120	2	14701760
Pubmed	The 5'-deiodinases are not essential for the fasting-induced decrease in circulating thyroid hormone levels in male mice: possible roles for the type 3 deiodinase and tissue sequestration of hormone.	DIO1 DIO2	3.53e-05	3	120	2	24635350
Pubmed	Negative Regulation of IKKε-Mediated IRF7 Phosphorylation by HSP70.	HSPA1A HSPA1B	3.53e-05	3	120	2	32169844
Pubmed	Identification of two new members of the CSMD gene family.	CSMD3 CSMD1	3.53e-05	3	120	2	12906867
Interaction	STX6 interactions	VPS11 ANKFY1 DSC2 VPS50 ARFGEF2 LMTK2 NIBAN2 ERBIN DST SNX6 CRYBG3 KIF13A STX11	2.28e-06	448	118	13	int:STX6
Interaction	DNAJC7 interactions	UBE4B MKNK1 KIAA0753 ABCE1 SVIL BUB1B PWP2 IFT122 ALDH1B1 HSPA1A HSPA1B DYNC1I1	7.53e-06	425	118	12	int:DNAJC7
Cytoband	Ensembl 112 genes in cytogenetic band chr7q21	VPS50 LMTK2 PON2 DYNC1I1 SEMA3E	1.10e-04	178	120	5	chr7q21
Cytoband	7q21.3	VPS50 LMTK2 PON2	1.49e-04	39	120	3	7q21.3
GeneFamily	Acid sensing ion channel subunits	ASIC3 ASIC4	2.65e-04	5	94	2	290
GeneFamily	WD repeat domain containing\|UTPB complex	WDR36 PWP2	3.96e-04	6	94	2	1225
GeneFamily	Methyltransferase like	METTL2A METTL22 METTL2B	6.63e-04	33	94	3	963
GeneFamily	Mitogen-activated protein kinase-activated protein kinases	RPS6KA2 MKNK1	1.43e-03	11	94	2	1156
GeneFamily	WD repeat domain containing	WDR36 NBEAL1 WDR87 PWP2 IFT122 DYNC1I1	2.46e-03	262	94	6	362
GeneFamily	Hyalectan proteoglycans\|V-set domain containing\|Sushi domain containing\|C-type lectin domain containing	CD46 CSMD3 CSMD1	3.25e-03	57	94	3	1179
GeneFamily	Dyneins, axonemal	DNAH12 DNAH8	3.46e-03	17	94	2	536
GeneFamily	Heat shock 70kDa proteins	HSPA1A HSPA1B	3.46e-03	17	94	2	583
GeneFamily	Aldehyde dehydrogenases	ALDH1A1 ALDH1B1	4.32e-03	19	94	2	398
CoexpressionAtlas	DevelopingLowerUrinaryTract_e13.5_bladder neck-urethr epithel_emap-30875_top-relative-expression-ranked_1000	KPNA4 CLXN DSC2 ZNF316 PON2 PEX13 RNF217 TBC1D9 PPP2R1B DST TLL1 DIO2 ALDH1A1 KIF13A HSPA1A HSPA1B SLC27A2 SEMA3E	3.87e-07	800	117	18	gudmap_developingLowerUrinaryTract_e13.5_bladder neck-urethr epithel_1000
CoexpressionAtlas	dev gonad_e12.5_M_SertoliCell_Sox9_top-relative-expression-ranked_500	PDE2A DSC2 RPS6KA2 GSTM2 XYLT1 DOCK5 DST SVIL ALDH1A1 ALDH1B1 CNGA1	3.30e-05	441	117	11	gudmap_dev gonad_e12.5_M_SertoliCell_Sox9_500
ToppCell	droplet-Bladder-nan-24m-Epithelial-nan\|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DAPK2 LBP RNF157 KCNA2 MMP3 CSMD1 HSPA1A	5.71e-07	179	120	7	dfd9d29281510d32f1a2e8336d2e58ef496cfd1d
ToppCell	PND07-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-VEC-VEC_prolif\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	THEMIS LBP TLL1 KATNIP CRYBG3 DYNC1I1	6.37e-06	168	120	6	32e4d82efaccf336d347e4063253c3635a3ec672
ToppCell	E16.5-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Deuterosomal-Deuterosomal_prolif\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	DAPK2 DNAH12 ALDH1A1 CFAP70 CSMD1 SLC27A2	7.05e-06	171	120	6	4f2a83d8091f1fd29542d2e5add57fd482e921b5
ToppCell	3'_v3-blood-Mast\|blood / Manually curated celltypes from each tissue	DAPK2 LMTK2 KIAA1549 CCR3 ALDH1A1 SLC27A2	7.29e-06	172	120	6	e7a46bbeff749ca59b9f1357409ce1ad59dd22dd
ToppCell	primary_auditory_cortex_(A1C)-Neuronal-Glutamatergic_Excit-Glut_E_(THEMIS)-Glut_IT_L5/L6_Car3_THEMIS-Exc_L6_THEMIS_C6orf48\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	THEMIS SMYD1 NIBAN2 TLL1 HHIPL2 ALDH1A1	7.53e-06	173	120	6	8bc916ccf687df0341ec1d77d62844bf890cad47
ToppCell	3'_v3-blood-Mast-Mast_cell_granulo-myelo\|blood / Manually curated celltypes from each tissue	DAPK2 KIAA1549 CAB39L ALDH1A1 HSPA1A SLC27A2	8.31e-06	176	120	6	d421b6b8e13894dbcf29548c0a6516c3dee8f9b1
ToppCell	facs-Brain_Non-Myeloid-Striatum_-18m-Mesenchymal-Ependyma\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CLXN LBP TBC1D9 IQCA1 CAB39L CFAP70	9.44e-06	180	120	6	729f0d7af573c7796d8e28e6eec3af2fc0bd33a2
ToppCell	facs-Brain_Non-Myeloid-Striatum_-18m-Mesenchymal-ependymal_cell\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CLXN LBP TBC1D9 IQCA1 CAB39L CFAP70	9.44e-06	180	120	6	9ef79a7c60227e352ac166c7274adb31f585f5ca
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_3\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	GPT KIAA1549 LBP DIO1 CSMD1 SLC27A2	1.04e-05	183	120	6	85446581999cd66b171c4f69b7eb8b0bbbaa8617
ToppCell	PND14-Epithelial-Epithelial_Airway\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CLXN DNAH12 IQCA1 ALDH1A1 CFAP70 SEMA3E	1.17e-05	187	120	6	1399c703505211c510b3f14c7a2aa9930566c473
ToppCell	ILEUM-inflamed-(3)_MNP-(3)_moDC\|(3)_MNP / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)	STAB1 DOCK5 FRMD4A DST HSPA1A HSPA1B	1.17e-05	187	120	6	0099def970fbc828756fbf853eca2ce77b8cd342
ToppCell	P15-Epithelial-airway_epithelial_cell-club_cell\|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	CLXN EFCAB6 MFSD6L DNAH12 IQCA1 CFAP70	1.17e-05	187	120	6	a70aaae32426e9ddb1cbfbd0e0db24ccc96b9f40
ToppCell	P15-Epithelial-airway_epithelial_cell\|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	CLXN EFCAB6 MFSD6L DNAH12 IQCA1 CFAP70	1.21e-05	188	120	6	e3e71c0f2e374330620cb4d27638953ffa9f5298
ToppCell	BAL-Severe-Myeloid-TRAM-TRAM1-\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	DSC2 FRMD4A DST NALCN SVIL ALDH1A1	1.28e-05	190	120	6	0eef5a8bd88ef8a25a67d9dd522d9472fa4b3d2f
ToppCell	BAL-Severe-Myeloid-TRAM-TRAM1\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	DSC2 FRMD4A DST NALCN SVIL ALDH1A1	1.28e-05	190	120	6	2724e8f375d8d9f5f2a77444e0491af264babac5
ToppCell	PND14-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Ciliated\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CLXN DNAH12 IQCA1 ALDH1A1 CFAP70 SEMA3E	1.28e-05	190	120	6	088e3f39a1e5e11354d6e7458e8e6a39f14936b3
ToppCell	PND14-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CLXN DNAH12 IQCA1 ALDH1A1 CFAP70 SEMA3E	1.28e-05	190	120	6	35248a8be476ea8d06d67c3d98a25be1f7c150b7
ToppCell	PND14-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Ciliated-Ciliated_mature\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CLXN DNAH12 IQCA1 ALDH1A1 CFAP70 SEMA3E	1.28e-05	190	120	6	5f5206f9e725070d865f4c891ff08bb750e58582
ToppCell	BAL-Severe-Myeloid-TRAM-TRAM1-\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	DSC2 FRMD4A DST NALCN SVIL ALDH1A1	1.28e-05	190	120	6	11fbd4e9f02750354b3aadf30edc991f8d4f8f41
ToppCell	BAL-Severe-Myeloid-TRAM-TRAM1\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	DSC2 FRMD4A DST NALCN SVIL ALDH1A1	1.28e-05	190	120	6	148d43dd72e2e22b2cd68e17fedae6bd98b32aee
ToppCell	Severe_COVID-19-Myeloid-TRAM1\|Severe_COVID-19 / Disease group,lineage and cell class （2021.01.30）	DSC2 FRMD4A DST NALCN SVIL ALDH1A1	1.32e-05	191	120	6	bd641aab36276dd952a7265ee79ba455b38d8e6b
ToppCell	mild-HLA-DR-_S100A+_Monocyte\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	DSC2 NIBAN2 TBC1D9 STAB1 DOCK5 KIF13A	1.67e-05	199	120	6	d0d286eafe935f9b3aaba5b783e8911251121b4a
ToppCell	Macroglial-Polydendrocytes-PDGFRA-\|Macroglial / cells hierarchy compared to all cells using T-Statistic	CSMD3 XYLT1 TLL1 SLC4A10 ASIC4 CSMD1	1.72e-05	200	120	6	f17b5a54e8f9eba9dcd0808ba4e8d275ac41bce2
ToppCell	Macroglial-Polydendrocytes-PDGFRA--\|Macroglial / cells hierarchy compared to all cells using T-Statistic	CSMD3 XYLT1 TLL1 SLC4A10 ASIC4 CSMD1	1.72e-05	200	120	6	cc3409518f8b436ea92deb955e81114b3f410ff7
ToppCell	Macroglial-Polydendrocytes-PDGFRA\|Macroglial / cells hierarchy compared to all cells using T-Statistic	CSMD3 XYLT1 TLL1 SLC4A10 ASIC4 CSMD1	1.72e-05	200	120	6	c24a3099e3d96d8b72f6d05286bb355d661a0377
ToppCell	Tracheal-10x3prime_v2-Epithelial\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	CLXN DNAH12 IQCA1 ALDH1A1 CFAP70 SLC27A2	1.72e-05	200	120	6	e1da1b15d2ca06796ee1ab7cef586ae0b4dc0a0a
ToppCell	Macroglial-Polydendrocytes-PDGFRA---\|Macroglial / cells hierarchy compared to all cells using T-Statistic	CSMD3 XYLT1 TLL1 SLC4A10 ASIC4 CSMD1	1.72e-05	200	120	6	4fc3de4bff7ed2bf40b38462c4b4e9b87af6a4ca
ToppCell	Macroglial-Polydendrocytes-PDGFRA----L1-6\|Macroglial / cells hierarchy compared to all cells using T-Statistic	CSMD3 XYLT1 TLL1 SLC4A10 ASIC4 CSMD1	1.72e-05	200	120	6	310cd53db1c137f6af74e6ae682221d7ac27310c
ToppCell	Macroglial-Polydendrocytes\|Macroglial / cells hierarchy compared to all cells using T-Statistic	CSMD3 XYLT1 TLL1 SLC4A10 ASIC4 CSMD1	1.72e-05	200	120	6	961858738ce35db8760c8c2e136f8369bc444ccf
ToppCell	343B-Lymphocytic-CD8+_Cytotoxic_T-cell\|343B / Donor, Lineage, Cell class and subclass (all cells)	THEMIS MYO1H CSMD3 RNF157 SLC4A10	3.38e-05	136	120	5	b4a934feea46eeb10d407d1545bd225173078792
ToppCell	PND01-03-samps-Epithelial-Epithelial-non_alveolar\|PND01-03-samps / Age Group, Lineage, Cell class and subclass	CLXN EFCAB6 MFSD6L CFAP70 SLC27A2	5.93e-05	153	120	5	fc0d2d50aa3b6b2772bbf3626c9df5c5e8d7d11e
ToppCell	PND01-03-samps-Epithelial-Epithelial-non_alveolar-Ciliated_cell_of_lung_parenchyma\|PND01-03-samps / Age Group, Lineage, Cell class and subclass	CLXN EFCAB6 MFSD6L CFAP70 SLC27A2	5.93e-05	153	120	5	2482247d9c39c7b99bb45fb9153442f64fd6012f
ToppCell	COVID-19_Severe-CD8+_T_naive\|World / disease group, cell group and cell class	TRABD2A THEMIS RCAN3 RNF157 IQCA1	6.11e-05	154	120	5	b568417d88a78d8c46688847f0f5f4989bd36387
ToppCell	mild_COVID-19_(asymptomatic)-CD8+_T_naive\|mild_COVID-19_(asymptomatic) / disease group, cell group and cell class (v2)	TRABD2A RCAN3 RNF157 PGBD4 SEMA3E	6.30e-05	155	120	5	e2c901d5c9e42d25d7702e5e8fc19b06f7c817be
ToppCell	facs-Marrow-KLS-3m-Lymphocytic-BM_CD8_+_CD4_T_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	THEMIS DAPK2 RAVER2 CSMD1 DNAH8	7.11e-05	159	120	5	e967b557fe6ae4879d36f62c0297cbf6a2ad1ce9
ToppCell	facs-Marrow-KLS-3m-Lymphocytic-mature_alpha-beta_T_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	THEMIS DAPK2 RAVER2 CSMD1 DNAH8	7.11e-05	159	120	5	9db971130509c62d439e0cab16588a4d994d7aa0
ToppCell	E16.5-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Deuterosomal-Deuterosomal_G2M\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	DAPK2 DNAH12 IQCA1 ALDH1A1 CFAP70	8.23e-05	164	120	5	d9531848105d606adedde65426177cf851140e31
ToppCell	droplet-Liver-LIVER_HEPATOCYTES-30m-Lymphocytic\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PRDM5 CSMD3 HSPA1A HSPA1B SEMA3E	8.96e-05	167	120	5	e1b1a952fce27ab9cf16919b290625ff4a75261e
ToppCell	COVID-19-Heart-Neuronal\|COVID-19 / Disease (COVID-19 only), tissue and cell type	DOCK5 FRMD4A DST CAB39L ALDH1A1	9.22e-05	168	120	5	88c2c574f428c2502b5fe099bd73b0758f668ef6
ToppCell	BAL-Severe-Myeloid-cDC-cDC-cDC_4\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	TRABD2A DSC2 GPT PON2 CSMD1	9.22e-05	168	120	5	d60f7cd8269f373827f49c7785002cb38e4570a9
ToppCell	343B-Lymphocytic-NK_cells-NK_cell_B0\|NK_cells / Donor, Lineage, Cell class and subclass (all cells)	THEMIS MKNK1 DIO2 C1QTNF1 SEMA3E	9.48e-05	169	120	5	89b5452e0d8d058648a1d2659f1611fd6aebc6b6
ToppCell	BAL-Severe-Myeloid-cDC-cDC-cDC_4\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	TRABD2A DSC2 GPT PON2 CSMD1	9.48e-05	169	120	5	ccd98f9005aa0a88bd49f153be4e7200cc3dd0ac
ToppCell	PND10-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2-AF2_prolif\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ZNF316 PRDM5 C1QTNF1 MMP3 ALDH1B1	9.74e-05	170	120	5	8465c3069bbc08705d070927e712b6bc85ac7c5b
ToppCell	Ciliated_cells-B-IPF_04\|World / lung cells shred on cell class, cell subclass, sample id	CLXN SERPINB8 DNAH12 IQCA1 CFAP70	1.03e-04	172	120	5	187ae91148d293537afc77e10da2b64302322224
ToppCell	facs-Brain_Myeloid-Hippocampus-3m-Myeloid-macrophage\|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LMTK2 XYLT1 DOCK5 MMP3 STX11	1.06e-04	173	120	5	c63a615998d13b1725b5767f4ad2ec7e2b61db68
ToppCell	AT1_cells-Donor_07\|World / lung cells shred on cell class, cell subclass, sample id	SERPINB8 ALDH1B1 HSPA1A HSPA1B SEMA3E	1.06e-04	173	120	5	b29816427428c7053017477f59b828bf1357f3b2
ToppCell	droplet-Liver-LIVER_HEPATOCYTES-30m-Lymphocytic-B_cell\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CD46 PRDM5 CSMD3 HSPA1A HSPA1B	1.12e-04	175	120	5	59249c9e83952d7277010e7be3c779e26399eb5d
ToppCell	droplet-Liver-LIVER_HEPATOCYTES-30m-Lymphocytic-B_cell\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CD46 PRDM5 CSMD3 HSPA1A HSPA1B	1.12e-04	175	120	5	b35cc1357495f2a03a6500f807c6e6f8c877734d
ToppCell	facs-Marrow-KLS-18m-Lymphocytic-early_pro_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	VPS11 DIO2 ALDH1B1 STX11 DNAH8	1.15e-04	176	120	5	7292e014b8f697f0c2e9f47c48333de95cb44a69
ToppCell	droplet-Large_Intestine-COLON_-_"PROM_Tm"\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GPT PHOSPHO1 ALDH1A1 HSPA1A HSPA1B	1.15e-04	176	120	5	3c3b6c02d7acdc1305878ee34e9cbabbf9e87892
ToppCell	droplet-Large_Intestine-COLON_-_"PROM_Tm"-30m\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GPT PHOSPHO1 ALDH1A1 HSPA1A HSPA1B	1.15e-04	176	120	5	7c743b7e954c1ebfa289ed529abacb88504112ea
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_3\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	GPT SLC26A9 DIO1 CSMD1 SLC27A2	1.15e-04	176	120	5	1595dbeee336a81e581325d63208ec6262664ee9
ToppCell	facs-Marrow-KLS-18m-Lymphocytic-early_pro-B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	VPS11 DIO2 ALDH1B1 STX11 DNAH8	1.15e-04	176	120	5	88ca2f83d8301633232735f39b0683efe49d0b86
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_3\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	GPT KIAA1549 DIO1 CSMD1 SLC27A2	1.18e-04	177	120	5	2f81b26be89cc2fd8eafadaf7eae3c6ad6521462
ToppCell	droplet-Limb_Muscle-nan-24m-Endothelial-unknown\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ZNF316 CSMD3 KIAA0753 XYLT1 KCNA2	1.21e-04	178	120	5	f2002a5c4758d0af6c1880ca12f0af0d5e8888e4
ToppCell	E17.5-Endothelial-large_vessel_endothelial_cell-endothelial_cell_of_vein\|E17.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	PDE2A LBP DST TLL1 DYNC1I1	1.21e-04	178	120	5	0139b42494c1186390b12106dea7957e2b6717c2
ToppCell	droplet-Fat-BAT+GAT+MAT-30m-Epithelial\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CLXN EFCAB6 SLC26A9 CFAP70 SLC27A2	1.21e-04	178	120	5	58857bb8c13e0e1c6d9f5c1258f00fff62063d68
ToppCell	droplet-Spleen-nan-24m-Hematologic-erythroblast\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DAPK2 FRMD4A PHOSPHO1 FECH ALDH1A1	1.21e-04	178	120	5	9c4950357087212b2388116ba8866c359628694d
ToppCell	droplet-Fat-BAT+GAT+MAT-30m-Epithelial-nan\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CLXN EFCAB6 SLC26A9 CFAP70 SLC27A2	1.21e-04	178	120	5	8b7df6ab8709d9ab9dff97677cc4561aec2745bc
ToppCell	droplet-Fat-BAT+GAT+MAT-30m-Epithelial-epithelial_cell\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CLXN EFCAB6 SLC26A9 CFAP70 SLC27A2	1.21e-04	178	120	5	b0baf5667e3301898b3e45e974b8a8530af6a338
ToppCell	5'-Adult-Appendix-Epithelial-Tuft-related-Microfold_cell\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	TRABD2A DSC2 SMYD1 GPT KCNA2	1.24e-04	179	120	5	7aa4137f672dadb3be92009cde6e0ea60a15372d
ToppCell	368C-Lymphocytic-ILC-ILC-2\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	POLH ZNF316 XYLT1 DOCK5 ALDH1A1	1.27e-04	180	120	5	eb5a57604c7f2ad256c300085dbf5069d0ae1ad0
ToppCell	368C-Lymphocytic-ILC\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	POLH ZNF316 XYLT1 DOCK5 ALDH1A1	1.27e-04	180	120	5	ddba4dc3bbcfe4e4a22400be73bbc62d3ff27d3c
ToppCell	Mesenchymal_cells-Chondrocytes\|Mesenchymal_cells / Lineage and Cell class	CLXN NIBAN2 XYLT1 HHIPL2 DYNC1I1	1.27e-04	180	120	5	6e399368430ef3afa9ce1ef0ed90f614ccef9987
ToppCell	facs-Brain_Non-Myeloid-Cerebellum-3m-Mesenchymal-ependymal_cell\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CLXN MFSD6L LBP IQCA1 CFAP70	1.34e-04	182	120	5	587636c0f127231de21acd8aa632b74ff22ca8c2
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_3\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	GPT SLC26A9 DIO1 CSMD1 SLC27A2	1.34e-04	182	120	5	4a9c13932e7163fd37a3dcc4c6ca3bbea5372459
ToppCell	droplet-Heart-4Chambers-18m-Neuronal-cardiac_neuron\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	XYLT1 KCNA2 ALDH1A1 CSMD1 SEMA3E	1.34e-04	182	120	5	6fdaf3c8c3952a8f14dd7288e523ed58eb1d3517
ToppCell	facs-Brain_Non-Myeloid-Cerebellum-3m-Mesenchymal-Ependyma\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CLXN MFSD6L LBP IQCA1 CFAP70	1.34e-04	182	120	5	adfadd7893e74b3002f13f00875e3667d3493e0c
ToppCell	kidney_cells-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_3\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	GPT SLC26A9 LBP CSMD1 SLC27A2	1.38e-04	183	120	5	d73cac83cde82665f110baad7cf28db75f9ffe52
ToppCell	Healthy-CD8+_T_naive\|Healthy / disease group, cell group and cell class	TRABD2A THEMIS RCAN3 RNF157 IQCA1	1.38e-04	183	120	5	5e7a611cfb8a21106bb07361878ccc77ff251502
ToppCell	droplet-Kidney-nan-21m-Epithelial-Pecam____kidney_capillary_endothelial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ASIC3 C1QTNF1 ASIC4 DYNC1I1 SEMA3E	1.38e-04	183	120	5	f55081068213cc1cdb2acad58ff10f6b48b44c72
ToppCell	Mesenchymal_cells-Chondrocytes\|World / Lineage and Cell class	CLXN NIBAN2 XYLT1 HHIPL2 DYNC1I1	1.41e-04	184	120	5	1e03f9f08de5ad4d45388a95afad9f23ff0d0e28
ToppCell	droplet-Limb_Muscle-nan-3m-Macroglial-unknown\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CSMD3 KCNA2 CSMD1 STX11 SEMA3E	1.41e-04	184	120	5	da8d6e7944eb35e6cbea2feb7cbc2894787d723f
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d03-09-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c02-GPR183\|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)	TRABD2A THEMIS ASIC3 RCAN3 RNF157	1.45e-04	185	120	5	847257d232b9993cad50c814fd4ffeef52385295
ToppCell	remission-CD8+_T_naive\|World / disease stage, cell group and cell class	TRABD2A PRDM5 RCAN3 IQCA1 SEMA3E	1.45e-04	185	120	5	69304d7dd406ac7e96d51c239d7035a06d88704f
ToppCell	CV-Moderate-7\|Moderate / Virus stimulation, Condition and Cluster	ANKFY1 WDR36 CD46 DENND4B SLC27A2	1.45e-04	185	120	5	a6c9203ce6c2892a4a369c9bcfb85720f01cbb3f
ToppCell	droplet-Kidney-KIDNEY-1m-Epithelial-Epcam____podocyte\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LBP GSTM2 RAVER2 C1QTNF1 SEMA3E	1.45e-04	185	120	5	872720275789d249c9859de825a923803d458875
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_3\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	GPT KIAA1549 DIO1 CSMD1 SLC27A2	1.48e-04	186	120	5	a417e1e21313a7e05951038cdef5ac672a9f727c
ToppCell	Smart-seq2-lymph_node_(Smart-seq2)-lymphocytic-innate_lymphocytic\|lymph_node_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	GSTM2 DOCK5 DST SVIL SLC4A10	1.48e-04	186	120	5	855c2e5a8a6cf94c7de31982e0e2416f924439d3
ToppCell	severe_influenza-RBC\|World / disease group, cell group and cell class (v2)	FRMD4A PHOSPHO1 FECH HSPA1A HSPA1B	1.52e-04	187	120	5	f846750575f318503d21ade30f5bfd2e1d4c84af
ToppCell	Primary_Visual_cortex_(V1C)-Non-neuronal-Macroglial-Oligo-OPC\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	PON2 XYLT1 TLL1 ASIC4 KIF13A	1.52e-04	187	120	5	daff7ccd3f1924cf2b34d3aca3eccde245aaf371
ToppCell	ILEUM-inflamed-(1)_CD8_Trm\|inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)	THEMIS DAPK2 RCAN3 ASIC4 HSPA1B	1.52e-04	187	120	5	a77d7ae44f47410bd92fb3aa0f44dce891752b63
ToppCell	10x5'-lymph-node_spleen-Hematopoietic_Erythro-Mega-Erythrocytic_early\|lymph-node_spleen / Manually curated celltypes from each tissue	GPT NIBAN2 FECH BUB1B ALDH1A1	1.52e-04	187	120	5	61d346c9873c2edb3ce224a0c063c54d9a68309e
ToppCell	Monocytes-M2-like_CD16+_macrophages\|Monocytes / Immune cells in Kidney/Urine in Lupus Nephritis	MKNK1 STAB1 FRMD4A SNX6 ALDH1A1	1.52e-04	187	120	5	59e31c51183ed4c9a3d0792c8005ea3a12b28dfa
ToppCell	Primary_Visual_cortex_(V1C)-Non-neuronal-Macroglial-Oligo-OPC-OPC_L1-6_MYT1\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	PON2 XYLT1 TLL1 ASIC4 KIF13A	1.52e-04	187	120	5	5b7a1edee602e55d3400dc17dbb6b8aaa26defc0
ToppCell	P03-Endothelial-large_vessel_endothelial_cell-endothelial_cell_of_vein\|P03 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	PDE2A LBP DST TLL1 DYNC1I1	1.56e-04	188	120	5	5eb107122064f0a99dfd445cc87d3766f7257216
ToppCell	Epithelial-Epithelial-D_(Ciliated)\|Epithelial / shred on cell class and cell subclass (v4)	CLXN DNAH12 IQCA1 ALDH1A1 CFAP70	1.56e-04	188	120	5	8f30535a32968a81a304315a49c0d90a77d36948
ToppCell	Influenza_Severe-RBC\|World / Disease group and Cell class	FRMD4A PHOSPHO1 FECH HSPA1A HSPA1B	1.56e-04	188	120	5	f0438e6a77ee1f0456cb65926685266fff470983
ToppCell	COVID-19-kidney-T-cells-2\|COVID-19 / Disease (COVID-19 only), tissue and cell type	TRABD2A THEMIS RNF157 HSPA1A HSPA1B	1.56e-04	188	120	5	15484c05cb496cd98ed3f79a6134c5cec8f09a4d
ToppCell	PND07-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Ciliated-Ciliated_mature\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CLXN DNAH12 IQCA1 ALDH1A1 CFAP70	1.60e-04	189	120	5	057d7a03fdbe779122b203619a6f947f49b84d28
ToppCell	PND01-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Ciliated-Ciliated_mature\|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CLXN DNAH12 IQCA1 ALDH1A1 CFAP70	1.60e-04	189	120	5	b55de812043b670cbde810d7d42f45909b6d66ef
ToppCell	PND10-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Ciliated-Ciliated_mature\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CLXN DNAH12 IQCA1 ALDH1A1 CFAP70	1.60e-04	189	120	5	02c6128a9ab5818e0881dcadafdad5f08b9a67cf
ToppCell	PND10-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Ciliated\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CLXN DNAH12 IQCA1 ALDH1A1 CFAP70	1.60e-04	189	120	5	164ea92ff6a1aa2ead1c9b8f64f99a9d65437232
ToppCell	PND10-Epithelial-Epithelial_Airway\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CLXN DNAH12 IQCA1 ALDH1A1 CFAP70	1.60e-04	189	120	5	407d8a59969d83f014600aae1a55092283a13970
ToppCell	Epithelial-D_(Ciliated)\|World / shred on cell class and cell subclass (v4)	CLXN DNAH12 IQCA1 ALDH1A1 CFAP70	1.60e-04	189	120	5	0bf560b595c7a8450a46bc821b742b67965bd9f9
ToppCell	PND07-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CLXN DNAH12 IQCA1 ALDH1A1 CFAP70	1.60e-04	189	120	5	9f57a131902d23494bf389baf6e6e2d99f88b2c8
ToppCell	PND10-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CLXN DNAH12 IQCA1 ALDH1A1 CFAP70	1.60e-04	189	120	5	a85099bd598a27ee64ee0664d051d89fa8d62fc9
ToppCell	PND01-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Ciliated\|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CLXN DNAH12 IQCA1 ALDH1A1 CFAP70	1.60e-04	189	120	5	4e83e49d1265ffe507fdb72924c77c4d1c73f0bd
ToppCell	PND07-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Ciliated\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CLXN DNAH12 IQCA1 ALDH1A1 CFAP70	1.60e-04	189	120	5	e443b02502edaefa94567a9e8af5756e8e11ff30
ToppCell	Children_(3_yrs)-Endothelial-endothelial_cell_of_lymph_vessel-D032\|Children_(3_yrs) / Lineage, Cell type, age group and donor	PDE2A DOCK5 NALCN TLL1 DYNC1I1	1.64e-04	190	120	5	6e6ce6dd549d1c38cfef5b3f8be06ab01ce344b7
Disease	Drug habituation	CSMD3 MKNK1 XYLT1 FRMD4A CSMD1 DNAH8	7.10e-06	115	118	6	C0013170
Disease	Drug abuse	CSMD3 MKNK1 XYLT1 FRMD4A CSMD1 DNAH8	7.10e-06	115	118	6	C0013146
Disease	Prescription Drug Abuse	CSMD3 MKNK1 XYLT1 FRMD4A CSMD1 DNAH8	7.10e-06	115	118	6	C4316881
Disease	Substance-Related Disorders	CSMD3 MKNK1 XYLT1 FRMD4A CSMD1 DNAH8	7.10e-06	115	118	6	C0236969
Disease	Drug Use Disorders	CSMD3 MKNK1 XYLT1 FRMD4A CSMD1 DNAH8	7.10e-06	115	118	6	C0013222
Disease	Drug Dependence	CSMD3 MKNK1 XYLT1 FRMD4A CSMD1 DNAH8	7.10e-06	115	118	6	C1510472
Disease	Substance Dependence	CSMD3 MKNK1 XYLT1 FRMD4A CSMD1 DNAH8	7.10e-06	115	118	6	C0038580
Disease	Substance Use Disorders	CSMD3 MKNK1 XYLT1 FRMD4A CSMD1 DNAH8	7.10e-06	115	118	6	C0038586
Disease	Organic Mental Disorders, Substance-Induced	CSMD3 MKNK1 XYLT1 FRMD4A CSMD1 DNAH8	7.10e-06	115	118	6	C0029231
Disease	Substance abuse problem	CSMD3 MKNK1 XYLT1 FRMD4A CSMD1 DNAH8	7.46e-06	116	118	6	C0740858
Disease	graft-versus-host disease (biomarker_via_orthology)	HSPA1A HSPA1B	1.57e-04	5	118	2	DOID:0081267 (biomarker_via_orthology)
Disease	vascular dementia (is_implicated_in)	PON2 HSPA1A	3.29e-04	7	118	2	DOID:8725 (is_implicated_in)
Disease	cerebrospinal fluid clusterin measurement	DST TLL1 CSMD1	3.72e-04	35	118	3	EFO_0007657
Disease	Major depression, single episode	HSPA1A HSPA1B	5.60e-04	9	118	2	C0024517
Disease	anti-topoisomerase-I-antibody-positive systemic scleroderma	IFT122 METTL22	6.99e-04	10	118	2	EFO_0008537
Disease	obstructive jaundice (biomarker_via_orthology)	GPT LBP	6.99e-04	10	118	2	DOID:13603 (biomarker_via_orthology)
Disease	Tourette syndrome	CSMD3 XYLT1 POLR3B	1.07e-03	50	118	3	EFO_0004895
Disease	Thyroid Diseases	DIO1 DIO2	1.20e-03	13	118	2	C0040128
Disease	glycodeoxycholate measurement	SVIL CSMD1	1.40e-03	14	118	2	EFO_0010493
Disease	Idiopathic hypogonadotropic hypogonadism	POLR3B SEMA3E	2.33e-03	18	118	2	C0342384
Disease	Profound Mental Retardation	UBR7 POLR3B KCNA2 SLC4A10	2.39e-03	139	118	4	C0020796
Disease	Mental Retardation, Psychosocial	UBR7 POLR3B KCNA2 SLC4A10	2.39e-03	139	118	4	C0025363
Disease	Mental deficiency	UBR7 POLR3B KCNA2 SLC4A10	2.39e-03	139	118	4	C0917816
Disease	emphysema imaging measurement	CAB39L MMP3 ALDH1B1 CSMD1	2.85e-03	146	118	4	EFO_0007626
Disease	periodontitis (biomarker_via_orthology)	LBP MMP3	3.17e-03	21	118	2	DOID:824 (biomarker_via_orthology)
Disease	Manic	RPS6KA2 STAB1 DNAH8	3.81e-03	78	118	3	C0338831
Disease	free androgen index	PDE2A UBE4B GSTM2 DOCK5 SERPINB8 TGFBRAP1	4.00e-03	374	118	6	EFO_0007005

Protein segments in the cluster

Peptide	Gene	Start	Entry
DFSYSVDLRVQLDVF	BUB1B	911	O60566
FLTDTIYDEDEVLLA	PPP2R1B	66	P30154
YVELSTFDIASDAFA	CAB39L	171	Q9H9S4
FAFEERLFLLADEVY	GPT	261	P24298
IFTFEKTLEELYLDA	ERBIN	41	Q96RT1
TFALEEDFDILSVYD	CSMD1	76	Q96PZ7
TDFQLEEGYDFLEIS	CSMD1	251	Q96PZ7
FEEFDLEIGYDTLTI	CSMD3	591	Q7Z407
TIFDNFLITDDEEYA	CALR3	311	Q96L12
DYVFEEPSISLFALE	CRYBG3	2746	Q68DQ2
FVEESIYNEFLERTV	ALDH1B1	326	P30837
FYEALNEVLLSDVFA	ARFGEF2	1416	Q9Y6D5
ASRIFVEESIYDEFV	ALDH1A1	306	P00352
EADLSGLDEVIFSYV	CUEDC2	21	Q9H467
YTESTIDFLDRAIFD	CCM2	221	Q9BSQ5
VELELTEFHYFDDIL	IQCA1	91	Q86XH1
VDREQYESFEIIAFA	DSC2	201	Q02487
VSSYEQFLDVDFEKL	NBEAL1	31	Q6ZS30
ERFEALFTIYDDQVT	RCAN3	66	Q9UKA8
ISFTSEEFEELVRAY	RAVER2	151	Q9HCJ3
ITDPLQYFELFFTEE	PGBD4	101	Q96DM1
QYFELFFTEELVSKI	PGBD4	106	Q96DM1
DFARFILVENTYEEV	NIBAN2	526	Q96TA1
FYLAVEDIETDTELL	PRDM5	106	Q9NQX1
VELKVYELFTDFTFL	KIAA1549	986	Q9HCM3
NFVEVLDEYFSRVSE	AP4S1	86	Q9Y587
IYTDELEFREDDVFL	ANKFY1	121	Q9P2R3
LVEEFSSVADFLLVY	DIO2	146	Q92813
LFSSAVYFAEADERE	KCNA2	341	P16389
EIDSFADIDYSLVEA	LBP	221	P18428
FYLEEGITDEEAISL	IFT122	1096	Q9HBG6
SEVEVFEYLDAVTYS	CD46	176	P15529
LETTAFDVQFFISEY	DST	3571	Q03001
FTTDDDILEAIFYSD	KATNIP	1126	O60303
VLYSLEFTFDADARV	MGRN1	116	O60291
EFTFDADARVAITIY	MGRN1	121	O60291
IFDIEDYIFTTEAHL	EDEM3	481	Q9BZQ6
DAAYEVTSKDLVFIF	MMP3	341	P08254
IERALAEDSDIFFDY	DYNC1I1	241	O14576
VADDSLYEFLDFVDA	MFSD6L	266	Q8IWD5
SLEIDSLFEGIDFYT	HSPA1B	281	P0DMV9
ELTNYLEDIEIFALF	PDE2A	676	O00408
TYDISQLFDFIDDLA	ERH	51	P84090
EAAVFLTLYEKVFED	DNAH8	2286	Q96JB1
IFTDSEIKDEAFLEY	DNAH8	2876	Q96JB1
DKITFVDFIAYDVLE	GSTM2	151	P28161
RVYFFTQEELDTLFT	METTL2B	321	Q6P1Q9
DEYTEFIEKFLSLAS	DNAH12	441	Q6ZR08
TAFEFNEYFLITILD	MTMR2	496	Q13614
VTFFDDVTVYLFDQE	LMTK2	1356	Q8IWU2
ETYIRENFLVLDVFF	ASIC4	406	Q96FT7
EAYIAENVLALDIFF	ASIC3	401	Q9UHC3
IDDILTVRFTTDYFE	DEFB118	81	Q96PH6
RVYFFTQEELDTLFT	METTL2A	321	Q96IZ6
ISTFIDNDDTVYLFV	PON2	116	Q15165
EDFSSIADFLVIYIE	DIO1	141	P49895
IFADEISFYELGSEA	KCNA10	161	Q16322
VILFSSAVYFAEVDE	KCNA10	386	Q16322
IDVDSEVVFELASYI	FRMD4A	131	Q9P2Q2
VVEHDLSVLDYLSDF	ABCE1	271	P61221
ENAIFSEELDTYITF	C1QTNF1	256	Q9BXJ1
SETYDFLVFDALVFI	DOCK5	686	Q9H7D0
EFLDSVAAIYEDLLS	CSTPP1	151	Q9H6J7
AVLAALPEFIFYETE	CCR3	161	P51677
YSINLSEEEFFHILE	EFCAB6	1466	Q5THR3
LANITAVSYDFDEEF	DAPK2	236	Q9UIK4
ELQTFISELYVFLVD	CFAP70	596	Q5T0N1
IEDASFLYELEIRFS	DHX57	346	Q6P158
EFLYDKALTFAETSE	DHX57	391	Q6P158
EEASLEFLLTDYEAV	DENND4B	541	O75064
SSAALDETLLDEFYI	IFNA8	96	P32881
SLEIDSLFEGIDFYT	HSPA1A	281	P0DMV8
AFTSDHIETLYELDI	FECH	336	P22830
IISFAEDEAGELYFL	HHIPL2	566	Q6UWX4
DFSTAELVDFILAFI	OR6B2	191	Q6IFH4
EFESFIDVYAIRSAE	PIP4K2C	346	Q8TBX8
IEFFEDDTRFYLVFE	MKNK1	111	Q9BUB5
DYVVNVTEEFLEFIS	KIF13A	931	Q9H1H9
EFTFDTDARVAITIY	RNF157	121	Q96PX1
LEIYLTDEDFEFALD	SVIL	2176	O95425
VTFIERSDEESYIVF	TLL1	191	O43897
DRAAYSLTLFDDEFE	SLC26A9	11	Q7LBE3
FLLFRDETLTYAQVD	SLC27A2	71	O14975
VLEEDLDIAVDFFSF	POMGNT1	391	Q8WZA1
DIIFAERAYSAVVFD	SMYD1	31	Q8NB12
YDFAAVSEEEISFRA	PEX13	281	Q92968
FAVIERASIDEAYVD	POLH	106	Q9Y253
ITECFEFLEETTVVY	RNF217	306	Q8TC41
EEISDLYDHTTILFA	METTL22	286	Q9BUU2
TILFAAEVFYDDDLT	METTL22	296	Q9BUU2
EDYAEAVFTSEFLEA	KIAA0753	951	Q2KHM9
DEFVVLALAELATSY	MROH2B	106	Q7Z745
DFSTAELVDFILAFI	OR6B3	191	Q8NGW1
FYQAELEELSFAEDT	SERPINB8	111	P50452
VRDSEYVFVVVDFLI	CNGA1	366	P29973
SFADYELAVREETLL	CLXN	166	Q9HAE3
LEEDITDSYLLISDF	THEMIS	481	Q8N1K5
IFKYDDFIFVLDIIS	VPS50	406	Q96JG6
FDISLFYRDIISIAE	XRCC6	211	P12956
SFPYVIALDDEFITV	TGFBRAP1	256	Q8WUH2
IAATYDILIESTAEF	XYLT1	791	Q86Y38
IAYSTVFEDVVDVLA	VPS11	321	Q9H270
ELYVEKVLEFLASSF	PWP2	796	Q15269
EDIVFETDHILESLY	STX11	31	O75558
VFAALPEFYVEDVAE	UBE4B	876	O95155
AVSFADVAVYFSREE	ZNF747	36	Q9BV97
FIYEALEKLFELSEA	SLC4A10	636	Q6U841
SFTIDELEELYALFK	TBC1D9	821	Q6ZT07
RFLLTFDFDETIVDE	PHOSPHO1	26	Q8TCT1
EAFLQSSIVYFELDL	TRABD2A	76	Q86V40
LDFLDDELTYKTLFV	STAB1	2356	Q9NY15
FEDFLHESLVEYLDV	POLR3B	621	Q9NW08
IEDEFDAYIIVSFVN	SF3B3	466	Q15393
VDDFFEHERTFLLEY	SNX6	206	Q9UNH7
ELVTFEDVAVYFSLE	ZNF316	156	A6NFI3
LDVLFLTDEYDTVLA	UBR7	326	Q8N806
GIDTYFDELEDVFLL	SEMA3E	301	O15041
YTFFIDILLDTIRDE	PSMD8	256	P48556
EELYRLQFIDSITFF	WDR87	286	Q6ZQQ6
FTDADDVAILTYVKE	TERF2IP	136	Q9NYB0
SEEEYLQLTFDKSVF	WDR36	191	Q8NI36
ELFLAAAETTVELVY	ZNF628	281	Q5EBL2
LAYEIIDQFFSSDDI	KPNA4	476	O00629
ASTLFEIDEFVKIYD	LEUTX	156	A8MZ59
FTEEDVKFYLAELAL	RPS6KA2	156	Q15349
DEFYLAEVAFTVLFD	NALCN	416	Q8IZF0
FVLLDAYTSESAFVD	MYO1H	16	Q8N1T3