Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyCellularComponentruffle membrane

PSD2 SRC ITGA5 PTPRZ1 TRPV4 PLCG1

7.24e-051081356GO:0032587
GeneOntologyCellularComponentruffle

PSD2 SRC ITGA5 PTPRZ1 FGD1 TRPV4 PLCG1

3.89e-042061357GO:0001726
GeneOntologyCellularComponentcell leading edge

PSD2 SRC ADGRV1 ITGA5 DUOX1 ARHGAP31 PTPRZ1 FGD1 TRPV4 PLCG1 SCRIB

4.09e-0450013511GO:0031252
GeneOntologyCellularComponentleading edge membrane

PSD2 SRC ADGRV1 ITGA5 PTPRZ1 TRPV4 PLCG1

4.37e-042101357GO:0031256
HumanPhenoBiliary tract neoplasm

STK11 BRCA2 PKHD1 ROS1

6.77e-0616424HP:0100574
DomainEGF_dom

NID2 CUBN MEGF8

6.92e-05121303IPR024731
DomainEGF_3

NID2 CUBN MEGF8

6.92e-05121303PF12947
Pubmed

Integrin alpha(v)beta(3) is a pleiotrophin receptor required for pleiotrophin-induced endothelial cell migration through receptor protein tyrosine phosphatase beta/zeta.

SRC ITGA5 PTPRZ1

1.24e-066139319141530
Pubmed

Small molecule inhibitors uncover synthetic genetic interactions of human flap endonuclease 1 (FEN1) with DNA damage response genes.

FANCD2 BRCA2 UBE2N

5.16e-069139328628639
Pubmed

Proteome-scale mapping of binding sites in the unstructured regions of the human proteome.

PRUNE2 AFTPH UBR4 TRIP12 LARP4B ZNF469 TNRC18 PIAS3 ARHGAP31 CLSPN

9.71e-064301391035044719
Pubmed

Specificity of the binding of synapsin I to Src homology 3 domains.

BIN1 SRC PLCG1

1.01e-0511139310899172
Pubmed

Defining the proximal interaction networks of Arf GTPases reveals a mechanism for the regulation of PLD1 and PI4KB.

SRC MCCC2 NCAPH TRIP12 CNNM3 VPS52 MKI67 GCC1 SCRIB CLSPN ADGRL2 SMAP2 PCDH7

1.54e-057771391335844135
Pubmed

Targeted disruption of the murine Bin1/Amphiphysin II gene does not disable endocytosis but results in embryonic cardiomyopathy with aberrant myofibril formation.

BIN1 MKI67

1.59e-052139212773571
Pubmed

Scribble, Lgl1, and myosin II form a complex in vivo to promote directed cell migration.

LLGL1 SCRIB

1.59e-052139232697665
Pubmed

The human papillomavirus type 16 E7 oncoprotein activates the Fanconi anemia (FA) pathway and causes accelerated chromosomal instability in FA cells.

FANCD2 BRCA2

1.59e-052139217898070
Pubmed

Steroid receptor coactivator-1 upregulates integrin α₅ expression to promote breast cancer cell adhesion and migration.

SRC ITGA5

1.59e-052139221343398
Pubmed

PLC-γ directly binds activated c-Src, which is necessary for carbachol-mediated inhibition of NHE3 activity in Caco-2/BBe cells.

SRC PLCG1

1.59e-052139223703528
Pubmed

Role of c-Src in regulation of endothelial nitric oxide synthase expression during exercise training.

SRC NOS3

1.59e-052139212595302
Pubmed

Pharmacological Characterization of a Betaine/GABA Transporter 1 (BGT1) Inhibitor Displaying an Unusual Biphasic Inhibition Profile and Anti-seizure Effects.

ADGRV1 SLC6A12

1.59e-052139232248400
Pubmed

DOCK4 stimulates MUC2 production through its effect on goblet cell differentiation.

DOCK4 MUC2

1.59e-052139233559155
Pubmed

Electrotransjection of pp60v-src monoclonal antibody inhibits activation of phospholipase C in platelets. A new mechanism for platelet-activating factor responses.

SRC PLCG1

1.59e-05213927510703
Pubmed

Evidence for LKB1/AMP-activated protein kinase/ endothelial nitric oxide synthase cascade regulated by hepatocyte growth factor, S-adenosylmethionine, and nitric oxide in hepatocyte proliferation.

STK11 NOS3

1.59e-052139219177591
Pubmed

BRCA/Fanconi anemia pathway implicates chemoresistance to gemcitabine in biliary tract cancer.

FANCD2 BRCA2

1.59e-052139225736055
Pubmed

Homozygous germ line mutation in exon 27 of murine Brca2 disrupts the Fancd2-Brca2 pathway in the homologous recombination-mediated DNA interstrand cross-links' repair but does not affect meiosis.

FANCD2 BRCA2

1.59e-052139216127665
Pubmed

Impaired TRPV4-eNOS signaling in trabecular meshwork elevates intraocular pressure in glaucoma.

TRPV4 NOS3

1.59e-052139233853948
Pubmed

AMBRA1 is involved in T cell receptor-mediated metabolic reprogramming through an ATG7-independent pathway.

ATG7 AMBRA1

1.59e-052139228789945
Pubmed

Histamine-mediated potentiation of transient receptor potential (TRP) ankyrin 1 and TRP vanilloid 4 signaling in submucosal neurons in patients with irritable bowel syndrome.

NEU1 TRPV4

1.59e-052139230629470
Pubmed

Microcell mediated chromosome transfer maps the Fanconi anaemia group D gene to chromosome 3p.

FANCD2 BRCA2

1.59e-05213927581463
Pubmed

Macroautophagy inhibition maintains fragmented mitochondria to foster T cell receptor-dependent apoptosis.

ATG7 AMBRA1

1.59e-052139227390127
Pubmed

AP180 binds to the C-terminal SH2 domain of phospholipase C-gamma1 and inhibits its enzymatic activity.

SNAP91 PLCG1

1.59e-052139211779129
Pubmed

Endothelial cell-derived matrix promotes the metabolic functional maturation of hepatocyte via integrin-Src signalling.

SRC ITGA5

1.59e-052139228470937
Pubmed

Interaction of transient receptor potential vanilloid 4, integrin, and SRC tyrosine kinase in mechanical hyperalgesia.

SRC TRPV4

1.59e-052139218234883
Pubmed

Positional cloning of a novel Fanconi anemia gene, FANCD2.

FANCD2 BRCA2

1.59e-052139211239453
Pubmed

Endothelial TRPV4-eNOS coupling as a vital therapy target for treatment of hypertension.

TRPV4 NOS3

1.59e-052139234822720
Pubmed

Cell cycle-related kinase is a crucial regulator for ciliogenesis and Hedgehog signaling in embryonic mouse lung development.

RFX2 MKI67 DNAH9 DNAH11

2.00e-0540139432317081
Pubmed

Hepatitis B Virus HBx Protein Mediates the Degradation of Host Restriction Factors through the Cullin 4 DDB1 E3 Ubiquitin Ligase Complex.

DMGDH DSC1 UBR4 ECPAS GSDMA DECR2 ADGRL2 CNOT1

3.25e-05304139832235678
Pubmed

PTPRA Phosphatase Regulates GDNF-Dependent RET Signaling and Inhibits the RET Mutant MEN2A Oncogenic Potential.

SRC FANCD2 LLGL1 PLCG1 PCDH7

3.91e-0594139532062451
Pubmed

Fanconi anemia complementation group D2 (FANCD2) functions independently of BRCA2- and RAD51-associated homologous recombination in response to DNA damage.

FANCD2 BRCA2

4.75e-053139215671039
Pubmed

Src Kinase Is the Connecting Player between Protein Kinase A (PKA) Activation and Hyperpolarization through SLO3 Potassium Channel Regulation in Mouse Sperm.

SRC KCNU1

4.75e-053139226060254
Pubmed

Combined inhibition of PLC{gamma}-1 and c-Src abrogates epidermal growth factor receptor-mediated head and neck squamous cell carcinoma invasion.

SRC PLCG1

4.75e-053139218594017
Pubmed

Regulation of asymmetric cell division and polarity by Scribble is not required for humoral immunity.

LLGL1 SCRIB

4.75e-053139223653213
Pubmed

TRPV4 activation of endothelial nitric oxide synthase resists nonalcoholic fatty liver disease by blocking CYP2E1-mediated redox toxicity.

TRPV4 NOS3

4.75e-053139227913210
Pubmed

ErbB2 requires integrin alpha5 for anoikis resistance via Src regulation of receptor activity in human mammary epithelial cells.

SRC ITGA5

4.75e-053139220332114
Pubmed

Fanconi anemia complementation group FANCD2 protein serine 331 phosphorylation is important for fanconi anemia pathway function and BRCA2 interaction.

FANCD2 BRCA2

4.75e-053139219861535
Pubmed

Autophagy compensates for Lkb1 loss to maintain adult mice homeostasis and survival.

ATG7 STK11

4.75e-053139233236987
Pubmed

Variant estrogen receptor-c-Src molecular interdependence and c-Src structural requirements for endothelial NO synthase activation.

SRC NOS3

4.75e-053139217921256
Pubmed

Differential regulation of Dlg1, Scrib, and Lgl1 expression in a transgenic mouse model of ocular cancer.

LLGL1 SCRIB

4.75e-053139219098995
Pubmed

Autophagy modulates lipid metabolism to maintain metabolic flexibility for Lkb1-deficient Kras-driven lung tumorigenesis.

ATG7 STK11

4.75e-053139230692209
Pubmed

Mechanism of RAD51-dependent DNA interstrand cross-link repair.

FANCD2 BRCA2

4.75e-053139221719678
Pubmed

Localization of phospholipase C-gamma 1 to mouse chromosome 2.

SRC PLCG1

4.75e-05313921358284
Pubmed

Ambra1 spatially regulates Src activity and Src/FAK-mediated cancer cell invasion via trafficking networks.

SRC AMBRA1

4.75e-053139228362576
Pubmed

The Fanconi Anemia Pathway Protects Genome Integrity from R-loops.

FANCD2 BRCA2

4.75e-053139226584049
Pubmed

Hyper-activation of pp60Src limits nitric oxide signaling by increasing asymmetric dimethylarginine levels during acute lung injury.

SRC NOS3

4.75e-053139227838434
Pubmed

Studies of protein-protein interactions in Fanconi anemia pathway to unravel the DNA interstrand crosslink repair mechanism.

FANCD2 BRCA2

4.75e-053139228684355
Pubmed

Oxidation-Dependent Activation of Src Kinase Mediates Epithelial IL-33 Production and Signaling during Acute Airway Allergen Challenge.

SRC DUOX1

4.75e-053139234088769
Pubmed

FANCD2 Maintains Fork Stability in BRCA1/2-Deficient Tumors and Promotes Alternative End-Joining DNA Repair.

FANCD2 BRCA2

4.75e-053139227264184
Pubmed

LPS induces pp60c-src-mediated tyrosine phosphorylation of Hsp90 in lung vascular endothelial cells and mouse lung.

SRC NOS3

4.75e-053139223585225
Pubmed

Epithelial cancer in Fanconi anemia complementation group D2 (Fancd2) knockout mice.

FANCD2 BRCA2

4.75e-053139212893777
Pubmed

Endothelial VEGFR2-PLCγ signaling regulates vascular permeability and antitumor immunity through eNOS/Src.

PLCG1 NOS3

4.75e-053139237651195
Pubmed

YAP/TAZ-Dependent Reprogramming of Colonic Epithelium Links ECM Remodeling to Tissue Regeneration.

SRC MKI67 MUC2

4.88e-0518139329249464
Pubmed

Global genetic analysis in mice unveils central role for cilia in congenital heart disease.

PIGV MEGF8 CC2D2A CPLANE1 DNAH11

5.27e-05100139525807483
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

CAND2 AMBRA1 ADGRV1 ECPAS NCAPH AMIGO3 SEMA5B ARHGAP31 ADGRL2 CNOT1

5.63e-055291391014621295
Pubmed

Systematic identification of SH3 domain-mediated human protein-protein interactions by peptide array target screening.

BIN1 SRC CSMD2 MEPE BRCA2 MKI67 PLCG1 SLC23A1

5.67e-05329139817474147
Pubmed

The transcriptional repressor Blimp1/Prdm1 regulates postnatal reprogramming of intestinal enterocytes.

NEU1 MKI67 MUC2

7.88e-0521139321670299
Pubmed

Systematic mapping of genetic interactions for de novo fatty acid synthesis identifies C12orf49 as a regulator of lipid metabolism.

NUDT21 UBR4 SYS1 VARS2 INO80D FANCD2 CNNM3 SNX14 VPS52 ANKRD11 HELZ PLCG1 CLSPN CNOT1 SLC23A1 PADI3

8.49e-0513271391632694731
Pubmed

FANCD2, FANCJ and BRCA2 cooperate to promote replication fork recovery independently of the Fanconi Anemia core complex.

FANCD2 BRCA2

9.47e-054139225659033
Pubmed

Identification of regions of the Wiskott-Aldrich syndrome protein responsible for association with selected Src homology 3 domains.

SRC PLCG1

9.47e-05413928824280
Pubmed

An inherent role of microtubule network in the action of nuclear receptor.

SRC PBXIP1

9.47e-054139217043237
Pubmed

ICAM-1-activated Src and eNOS signaling increase endothelial cell surface PECAM-1 adhesivity and neutrophil transmigration.

SRC NOS3

9.47e-054139222806890
Pubmed

Regulation of the hDlg/hScrib/Hugl-1 tumour suppressor complex.

LLGL1 SCRIB

9.47e-054139218793635
Pubmed

MERIT40 cooperates with BRCA2 to resolve DNA interstrand cross-links.

FANCD2 BRCA2

9.47e-054139226338419
Pubmed

Tip60 is required for DNA interstrand cross-link repair in the Fanconi anemia pathway.

FANCD2 BRCA2

9.47e-054139218263878
Pubmed

Alpha5beta1 integrin engagement increases large conductance, Ca2+-activated K+ channel current and Ca2+ sensitivity through c-src-mediated channel phosphorylation.

SRC ITGA5

9.47e-054139219887442
Pubmed

ATP-mediated transactivation of the epidermal growth factor receptor in airway epithelial cells involves DUOX1-dependent oxidation of Src and ADAM17.

SRC DUOX1

9.47e-054139223349873
Pubmed

Clustering of Genetic Anomalies of Cilia Outer Dynein Arm and Central Apparatus in Patients with Transposition of the Great Arteries.

DNAH9 DNAH11

9.47e-054139236140829
Pubmed

Defects of FA/BRCA pathway in lymphoma cell lines.

FANCD2 BRCA2

9.47e-054139219011769
Pubmed

Calcium-induced human keratinocyte differentiation requires src- and fyn-mediated phosphatidylinositol 3-kinase-dependent activation of phospholipase C-gamma1.

SRC PLCG1

9.47e-054139215872086
Pubmed

Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.

CAND2 AFTPH UBR4 MCCC2 VARS2 PPIB DNAJB3 TXNL1 CNNM3 LLGL1 UBE2N ANKRD11 SCRIB ADGRL2 SMAP2 PCDH7 PBXIP1

9.63e-0514871391733957083
Pubmed

Pro-prion, as a membrane adaptor protein for E3 ligase c-Cbl, facilitates the ubiquitination of IGF-1R, promoting melanoma metastasis.

DOCK4 PODNL1 TPRN UBR4 MCCC2 NCAPH PPIB TNRC18 MMP17 RUSF1 DNAH11

1.08e-046891391136543142
Pubmed

KAP1 facilitates reinstatement of heterochromatin after DNA replication.

CAND2 HDHD5 UBR4 NUP88 NCAPH TRIP12 FANCD2 ALDH4A1 PLCG1 SCRIB CNOT1

1.30e-047041391129955894
Pubmed

Expression of members of the putative olfactory receptor gene family in mammalian germ cells.

OR7A5 OR7D2 OR7A17

1.35e-042513931370859
Pubmed

TFAM is required for maturation of the fetal and adult intestinal epithelium.

CUBN MKI67 MUC2

1.52e-0426139329684311
Pubmed

Crystal structure of the alpha appendage of AP-2 reveals a recruitment platform for clathrin-coat assembly.

BIN1 SNAP91

1.57e-045139210430869
Pubmed

The CCR4-NOT deadenylase complex controls Atg7-dependent cell death and heart function.

ATG7 CNOT1

1.57e-045139229438013
Pubmed

The multiple-specificity landscape of modular peptide recognition domains.

SLC6A12 SCRIB

1.57e-045139221525870
Pubmed

Integrin-mediated signal transduction linked to Ras pathway by GRB2 binding to focal adhesion kinase.

SRC PLCG1

1.57e-04513927997267
Pubmed

Functional variant analyses (FVAs) predict pathogenicity in the BRCA1 DNA double-strand break repair pathway.

FANCD2 BRCA2

1.57e-045139225652403
Pubmed

The Csk-binding protein PAG regulates PDGF-induced Src mitogenic signaling via GM1.

SRC NEU1

1.57e-045139218695048
Pubmed

Tumor suppressor PALB2 maintains redox and mitochondrial homeostasis in the brain and cooperates with ATG7/autophagy to suppress neurodegeneration.

ATG7 BRCA2

1.57e-045139235404932
Pubmed

Nrf2 Transcriptional Activity Governs Intestine Development.

MKI67 MUC2

1.57e-045139235682851
Pubmed

Functional interaction of monoubiquitinated FANCD2 and BRCA2/FANCD1 in chromatin.

FANCD2 BRCA2

1.57e-045139215199141
Pubmed

Tyrosines 1021 and 1009 are phosphorylation sites in the carboxy terminus of the platelet-derived growth factor receptor beta subunit and are required for binding of phospholipase C gamma and a 64-kilodalton protein, respectively.

SRC PLCG1

1.57e-04513927678051
Pubmed

Functional interaction between the Fanconi Anemia D2 protein and proliferating cell nuclear antigen (PCNA) via a conserved putative PCNA interaction motif.

FANCD2 BRCA2

1.57e-045139219704162
Pubmed

DNAH11 Localization in the Proximal Region of Respiratory Cilia Defines Distinct Outer Dynein Arm Complexes.

DNAH9 DNAH11

1.57e-045139226909801
Pubmed

A Membrane-Tethered Ubiquitination Pathway Regulates Hedgehog Signaling and Heart Development.

RNF157 MEGF8

1.57e-045139232966817
Pubmed

Autophagy induction in atrophic muscle cells requires ULK1 activation by TRIM32 through unanchored K63-linked polyubiquitin chains.

AMBRA1 UBE2N

1.57e-045139231123703
Pubmed

A dynamic constitutive and inducible binding of c-Cbl by PLCgamma1 SH3 and SH2 domains (negatively) regulates antigen receptor-induced PLCgamma1 activation in lymphocytes.

SRC PLCG1

1.57e-045139212941616
Pubmed

Recruitment of fanconi anemia and breast cancer proteins to DNA damage sites is differentially governed by replication.

FANCD2 BRCA2

1.57e-045139219748364
Pubmed

Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.

NID2 TPRN AMBRA1 QTRT2 CHD9 INO80D FANCD2 LARP4B ZNF469 VPS52 HELZ SCRIB CLSPN ADGRL2

1.60e-0411161391431753913
Pubmed

Fibril treatment changes protein interactions of tau and α-synuclein in human neurons.

BIN1 NUDT21 UBR4 ECPAS TRIP12 VPS52 UBE2N PLCG1 SCRIB

1.87e-04498139936634849
Pubmed

A probability-based approach for high-throughput protein phosphorylation analysis and site localization.

AFTPH NUP88 NCAPH TRIP12 ZXDA LARP4B MKI67 SCRIB EPHA1

2.01e-04503139916964243
Pubmed

HSF1 phosphorylation establishes an active chromatin state via the TRRAP-TIP60 complex and promotes tumorigenesis.

DSC1 NUDT21 NUP88 TMED7 ECPAS NCAPH BRCA2 ZBTB25 MKI67 DCHS1 ROS1

2.35e-047541391135906200
Pubmed

Loss of p53 partially rescues embryonic development of Palb2 knockout mice but does not foster haploinsufficiency of Palb2 in tumour suppression.

BRCA2 MKI67

2.35e-046139221404276
Pubmed

Binding of SH2 domains of phospholipase C gamma 1, GAP, and Src to activated growth factor receptors.

SRC PLCG1

2.35e-04613922173144
Pubmed

FANCG promotes formation of a newly identified protein complex containing BRCA2, FANCD2 and XRCC3.

FANCD2 BRCA2

2.35e-046139218212739
Pubmed

p600 Plays Essential Roles in Fetal Development.

UBR4 MKI67

2.35e-046139223824717
Pubmed

Phospholipase C-gamma1 interacts with conserved phosphotyrosyl residues in the linker region of Syk and is a substrate for Syk.

SRC PLCG1

2.35e-04613928657103
Cytoband7q32.1

KCP GCC1 PRRT4

1.15e-043113937q32.1
CytobandEnsembl 112 genes in cytogenetic band chr7q32

KCP PLXNA4 GCC1 PRRT4

2.24e-04971394chr7q32
GeneFamilyMembrane associated guanylate kinases|PDZ domain containing|Scribble complex

LLGL1 SCRIB

1.43e-0448921224
ToppCellPCW_05-06-Neuronal-Neuronal_SCP-neuro_proliferating_SCP1_(1)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

TMPRSS9 ADGRV1 CSMD2 CRYM PTPRZ1 PLXNA4 KIAA1755 MMP17

1.18e-071851388a8946379fc066903fe8f4bc9cbf693b7b424a0cd
ToppCellfacs-Marrow-B-cells-24m-Lymphocytic-precursor_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KCP ADGRV1 CRYM PTPRZ1 PKHD1 ABCC12 DNAH9

6.91e-071601387c381ec6be8cf887861cc18f831a20db42f953fe1
ToppCellfacs-Marrow-B-cells-24m-Lymphocytic-pre_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KCP ADGRV1 CRYM PTPRZ1 PKHD1 ABCC12 DNAH9

6.91e-07160138725c8f3d2a6d14ff0ca0b965fce89d3ff22f40585
ToppCellnormal_Lung-Fibroblasts-Myofibroblasts|Fibroblasts / Location, Cell class and cell subclass

PODNL1 FAM53A RNF157 STMN4 ZNF469 PCDH7 LRRC17

8.16e-0716413879b4a6007abae992db871d9f6f731d5af724de30d
ToppCellPCW_05-06-Neuronal-Neuronal_SCP|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

ADGRV1 CSMD2 CRYM PTPRZ1 PLXNA4 KIAA1755 MMP17

1.64e-061821387b4fc5e4f5d8440a3c9ee0a6fd0da87b43cabc8c6
ToppCellproximal-Hematologic-Proliferating_Macrophage|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

NCAPH FANCD2 BRCA2 RECQL4 MKI67 CLSPN PRRT4

2.77e-0619713870b1fa881abbfcc54b322fc27124db3f8947af016
ToppCellproximal-3-Hematologic-Proliferating_Macrophage|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

NCAPH FANCD2 BRCA2 RECQL4 MKI67 CLSPN PRRT4

2.77e-0619713870dd9058aa19d1268ebba9a65555870224b5a5978
ToppCellproximal-Hematologic-Proliferating_Macrophage-3|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

NCAPH FANCD2 BRCA2 RECQL4 MKI67 CLSPN PRRT4

2.77e-0619713879243617b307acf3df40d93c41cd8d4788699a7ea
ToppCellFetal_brain-fetalBrain_Zhong_nature-GW19-Stem_cells-Stem_cells|GW19 / Sample Type, Dataset, Time_group, and Cell type.

MANEA ADGRV1 NCAPH RFX2 FANCD2 MKI67 CLSPN

2.86e-06198138750f236ab7ef6f00721f6cd714e3eee183077beeb
ToppCellFetal_brain-fetalBrain_Zhong_nature-GW19-Stem_cells|GW19 / Sample Type, Dataset, Time_group, and Cell type.

MANEA ADGRV1 NCAPH RFX2 FANCD2 MKI67 CLSPN

2.86e-061981387dc0c6189ff9dd76675f63acf1cbc7dda60e75f3f
ToppCellTracheal-NucSeq-Epithelial-Epi_airway_basal-Dividing_Basal|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

NCAPH FANCD2 BRCA2 RECQL4 MKI67 CLSPN PCDH7

2.86e-061981387f088badb90c6c2d916195f5649eda102119c9ac6
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW19-Stem_cells|GW19 / Sample Type, Dataset, Time_group, and Cell type.

MANEA NCAPH RFX2 FANCD2 BRCA2 MKI67 CLSPN

3.06e-06200138731dd81df9aa754a1e69b905bf9b8ce73ff8175aa
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW19-Stem_cells-Neuroepithelial_cell|GW19 / Sample Type, Dataset, Time_group, and Cell type.

MANEA NCAPH RFX2 FANCD2 BRCA2 MKI67 CLSPN

3.06e-06200138754174a485a82480726fa06efa6e050ddea77cb3c
ToppCellCOVID-19_Severe-CD8+_T_naive|World / disease group, cell group and cell class

CAND2 DSC1 ADGRV1 RNF157 CATSPERB LRRC17

8.64e-061541386b568417d88a78d8c46688847f0f5f4989bd36387
ToppCellVE-CD8-CD4_Treg|VE / Condition, Cell_class and T cell subcluster

ADGRV1 RNF157 DUOX1 ZC3H12D NOS3 TRPT1

1.11e-051611386a114f4f75859d9ef900e5146686438d051241429
ToppCelldroplet-Heart-nan-18m-Mesenchymal-nan|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KCP MCCC2 ADGRV1 DNAJB3 C2CD4D LRP3

1.32e-0516613869adceb746e67e955fd8b3e0984f4eed44b64a270
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

NCAPH BRCA2 RECQL4 MKI67 CLSPN PRRT4

1.37e-05167138650c29ea660bf07b890e4ac1a1985d0761d863dee
ToppCelldroplet-Heart-nan-24m-Hematologic-coronary_vascular_endothelial_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HDHD5 NCAPH BRCA2 MKI67 PLCG1 CLSPN

1.37e-051671386bad33497ceeab968a7eb8a48b921c6f936390743
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Cycling_Endothelial_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

NCAPH FANCD2 BRCA2 RECQL4 MKI67 CLSPN

1.37e-051671386bc132b51dec4e8f1cd2b2cd89f83641976e09292
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_G2M|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

NCAPH BRCA2 RECQL4 MKI67 CLSPN PRRT4

1.42e-051681386d35944fd9fea9934ce1e76b2b35d48e2300cca61
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_S-high|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

NCAPH FANCD2 BRCA2 RECQL4 MKI67 CLSPN

1.47e-0516913860bc8ef341ce307b19018d4ac8de0a4d04254209d
ToppCellfacs-Diaphragm-Limb_Muscle-24m|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADGRV1 CUBN PLXNA4 PKHD1 DNAH9 DNAH11

1.47e-05169138612bdc709bc000d7f9061ecd9fbd57233eaacb7e2
ToppCellfacs-Marrow-T-cells-3m-Myeloid-granulocytopoietic_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NCAPH FANCD2 SLC6A12 PIAS3 AMIGO3 MKI67

1.57e-051711386913bae728b5e653771a27c79a309eb023699f1d0
ToppCellfacs-Marrow-T-cells-3m-Myeloid-granulocytopoietic_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NCAPH FANCD2 SLC6A12 PIAS3 AMIGO3 MKI67

1.57e-051711386f28b2336057e353b96a6ff4581ec9fd0ca0789d9
ToppCell3'-GW_trimst-2-SmallIntestine-Neuronal-Glial_immature-ENCC/glia_Progenitor|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ADGRV1 RNF157 CRYM SNAP91 PTPRZ1 PLXNA4

1.57e-051711386b51bbeacb172e8b5de519ada85543d7ae9914b3c
ToppCell3'-GW_trimst-1.5-SmallIntestine-Neuronal-Glial_immature-ENCC/glia_Progenitor|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ADGRV1 ZXDA ZDHHC24 CRYM PTPRZ1 C2CD4D

1.67e-05173138623e50492bc673aff9df95d97f0b9be4ce57cbf01
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CSMD2 FANCD2 BRCA2 RECQL4 MKI67 CLSPN

2.09e-051801386f8a15c13d85c1bbbf86ce49bb6f86c368ddf22df
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PRUNE2 DMGDH RIPOR3 ADGRV1 SLC6A12 PKHD1

2.16e-0518113869d782ba5cf5a172cb4f447763fc50e5b13ef7dd9
ToppCellPCW_07-8.5-Neuronal-Neuronal_SCP-neuro_SCP_(0)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

CSMD2 CRYM PTPRZ1 PLXNA4 KIAA1755 MMP17

2.16e-051811386fad7ba168f541ac9d04edebc206f191e48bb7e99
ToppCell356C-Lymphocytic-CD4_T-cell-Proliferating_T_cell|356C / Donor, Lineage, Cell class and subclass (all cells)

TMPRSS9 RIPOR3 NCAPH FAM117A MKI67 CLSPN

2.16e-051811386be4f35c9eb5b3083acb2264128f095fac1f3da45
ToppCell5'-GW_trimst-1.5-LargeIntestine-Neuronal-Glial_immature-cycling_ENCC/glia|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ADGRV1 RNF157 CRYM PTPRZ1 MKI67 MMP17

2.16e-051811386f2ebeb4941510c4b6e50f2379c574d1778d6ced1
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_3|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PRUNE2 DMGDH RIPOR3 ADGRV1 SLC6A12 PKHD1

2.23e-051821386eb138aa1dca9373f1586600f258df06dcf56d81f
ToppCell10x5'-Liver-Lymphocytic_T_CD4/8-lo-Cycling_T|Liver / Manually curated celltypes from each tissue

NCAPH BRCA2 RECQL4 MKI67 CLSPN LRRC17

2.23e-05182138681557cdc88777f3bd4e1dd18a760b08fc29122ef
ToppCellPCW_05-06-Neuronal-Neuronal_SCP-neuro_proliferating_SCP2_(1)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

ADGRV1 CSMD2 CRYM PTPRZ1 PLXNA4 MMP17

2.23e-051821386f7f9be9c7ef8da9864d6aefe20043b26e1bb8697
ToppCellPBMC-Control-Myeloid-Neutrophil-immature_Neutrophil|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

ABHD2 ECPAS NCAPH FANCD2 SELENOO MKI67

2.37e-051841386a8c6028d745aaa6ee7842259238694cb50ce0526
ToppCellPBMC-Control-Myeloid-Neutrophil-immature_Neutrophil-Neu_4|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

ABHD2 ECPAS NCAPH FANCD2 SELENOO MKI67

2.37e-051841386081d045f3bc98a36f342de7d50f39c9a888dd7eb
ToppCellControl-Myeloid_G-immature_Neutrophil|Control / Disease group, lineage and cell class

ABHD2 ECPAS NCAPH FANCD2 SELENOO MKI67

2.37e-05184138645f873236f7e90fb78c8e291d3b5b92d121acec9
ToppCellPBMC-Control-Myeloid-Neutrophil-immature_Neutrophil|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

ABHD2 ECPAS NCAPH FANCD2 SELENOO MKI67

2.37e-05184138684c20730cd92b9aaa50077d7b625e37e7f9e91d2
ToppCellPBMC-Control-Myeloid-Neutrophil-immature_Neutrophil-Neu_4|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

ABHD2 ECPAS NCAPH FANCD2 SELENOO MKI67

2.37e-051841386d31d4116d1d196633784863781fa45673607a421
ToppCellControl-immature_Neutrophil-|Control / Disease condition and Cell class

ABHD2 ECPAS NCAPH FANCD2 SELENOO MKI67

2.37e-051841386c4e8ba82a6aa76c46f05a71d5f1c7926555318cf
ToppCellControl-immature_Neutrophil|Control / Disease condition and Cell class

ABHD2 ECPAS NCAPH FANCD2 SELENOO MKI67

2.37e-0518413862fdae5c6b3eb2232881d933a8c1061fda3623016
ToppCellBac-SEP-Lymphocyte-T_NK-T_NK_proliferative|Bac-SEP / Disease, Lineage and Cell Type

NCAPH FANCD2 BRCA2 RECQL4 MKI67 CLSPN

2.37e-051841386848d05afd5a2ef61fb8a09c0f5fa2a56fd5c160b
ToppCellPCW_07-8.5-Neuronal-Neuronal_SCP|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

CSMD2 CRYM PTPRZ1 PLXNA4 KIAA1755 MMP17

2.44e-05185138656c7a0dbf141728ac76b8c90af197719942ca67c
ToppCellPCW_05-06-Neuronal|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

ADGRV1 STMN4 PTPRZ1 PLXNA4 KIAA1755 MMP17

2.59e-05187138603a2ed85b171c887d4f3b0f4fe2e1cb4a853e658
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

NCAPH FANCD2 BRCA2 RECQL4 MKI67 CLSPN

2.59e-0518713869351fa87b69a951af85b10bf91fe9b1cce8c0517
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PRUNE2 DMGDH RIPOR3 ADGRV1 SLC6A12 PKHD1

2.59e-051871386c41a2c81dd2ceef303f39f699032aa7d6ea67cf0
ToppCell10x5'-Liver-Lymphocytic_NK-Cycling_NK|Liver / Manually curated celltypes from each tissue

NCAPH FANCD2 BRCA2 RECQL4 MKI67 CLSPN

2.67e-0518813865eb94e652a734c6f15c68a178e9d05f0febcf34c
ToppCellControl-Endothelial-Endothelial-FOXM1|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

NCAPH FANCD2 BRCA2 RECQL4 MKI67 CLSPN

2.75e-0518913861e1499b062d9c647c8f38b0c4e0d871d159be5dd
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_ascending_limb_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PRUNE2 RIPOR3 ADGRV1 SLC6A12 PLXNA4 PKHD1

2.84e-0519013861cf023e3c6924d6a06f353d4b62444b6f2fee8a7
ToppCellPrimary_Motor_Cortex_(M1)-Non-neuronal-Macroglial-Astro-Astrocyte|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

PSD2 ADGRV1 RFX2 ARHGAP31 PTPRZ1 PBXIP1

3.10e-051931386b03d908d4b8940927f72c76a1b0f237d13f39056
ToppCellNS-moderate-d_0-4|moderate / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

ADGRV1 PTPRZ1 CPLANE1 DNAH9 PCDH7 DNAH11

3.10e-051931386ea345d34440b25f65358a53dc72831998d1c3620
ToppCellPCW_10-12-Mesenchymal-Mesenchymal_myocytic-mes_proliferating_SM_(20)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

NCAPH FANCD2 BRCA2 RECQL4 PLXNA4 CLSPN

3.10e-051931386bbdfda6665941cfa1965418bb91ef9ff43b1326f
ToppCellPrimary_Motor_Cortex_(M1)-Non-neuronal-Macroglial-Astro|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

PSD2 ADGRV1 RFX2 ARHGAP31 PTPRZ1 PBXIP1

3.10e-05193138640edc07b6e7f19f6ee885fa5af0b63ef1b0f2468
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Afferent_/_Efferent_Arteriole_Endothelial_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

DOCK4 ITGA5 CC2D2B ARHGAP31 PLXNA4 NOS3

3.10e-0519313860b328f725f6feba263783eaca60c142e80df90f3
ToppCellPCW_07-8.5-Mesenchymal-Mesenchymal_myocytic-mes_proliferating_SM_(20)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

NCAPH FANCD2 BRCA2 MKI67 PLXNA4 CLSPN

3.10e-051931386516ea2c12bdc7a5dc676159d627e36f6abe13ef0
ToppCell3'-Distal_airway-Immune_Myeloid-Myeloid_macrophage-alveolar_macrophage-Alveolar_macrophage_proliferating-|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

NCAPH FANCD2 BRCA2 RECQL4 MKI67 CLSPN

3.10e-051931386444de545117dae8ab24a22880583ac2f0b2d6eac
ToppCell3'_v3-Lung-Myeloid_Mac-Cycling_Myeloid-Mac|Lung / Manually curated celltypes from each tissue

NCAPH FANCD2 BRCA2 RECQL4 MKI67 CLSPN

3.19e-051941386a8ae49157ca3f9e8b3f1750a995aee012dc859b6
ToppCellControl-Lymphocyte-T_NK-T_NK_proliferative|Control / Disease, Lineage and Cell Type

NCAPH FANCD2 BRCA2 RECQL4 MKI67 CLSPN

3.19e-051941386844731b7943d1cfca819b7b89e4e62067bfa0230
ToppCell(7)_Epithelial_cells-(7)_Epithelial-J_(AT1-AT2_progenitors)|(7)_Epithelial_cells / Lung cell shreds - cell class (v4) and cell subclass (v4)

NCAPH FANCD2 BRCA2 RECQL4 MKI67 CLSPN

3.19e-0519413864d6ae2b25db11a4ae6dadee83be5c8c05b1225c3
ToppCell10x5'-lymph-node_spleen-Lymphocytic_B_plasma-Plasmablasts|lymph-node_spleen / Manually curated celltypes from each tissue

NCAPH PPIB AMIGO3 RECQL4 MKI67 CLSPN

3.28e-0519513861390728b9a514db534e8bc6dcf72cf51a1065780
ToppCellPCW_10-12-Mesenchymal-Mesenchymal_cycling-mes_proliferating3_(7)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

NCAPH FANCD2 BRCA2 RECQL4 MKI67 CLSPN

3.47e-05197138684ed777cdba569200a3ef1654d8a12f17fcfb7f1
ToppCellCOVID-19_Severe-T/NK_proliferative|COVID-19_Severe / Disease condition and Cell class

NCAPH FANCD2 BRCA2 RECQL4 MKI67 CLSPN

3.47e-051971386718a84e9a8248080f2d964e7c6a3ba183ece9592
ToppCellmedial-2-Hematologic-Proliferating_Macrophage|2 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

NCAPH FANCD2 BRCA2 RECQL4 MKI67 CLSPN

3.57e-05198138664a2bcf5a9ba66a4fe08fbde33f1886c136cde8f
ToppCellmedial-Hematologic-Proliferating_Macrophage-2|medial / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

NCAPH FANCD2 BRCA2 RECQL4 MKI67 CLSPN

3.57e-051981386fcc14ac3eb5088b9d6cd6af5a34dee5b81c0ece8
ToppCelldistal-1-Hematologic-Proliferating_Macrophage|1 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

NCAPH FANCD2 BRCA2 RECQL4 MKI67 CLSPN

3.57e-051981386df3f5559ecd1f3cd1fd60e39dbad8741309e83a3
ToppCelldistal-Hematologic-Proliferating_Macrophage-2|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

NCAPH FANCD2 BRCA2 RECQL4 MKI67 CLSPN

3.57e-0519813868afeb1f9bc9d8551482c8fefe4c5f88d9cd13ee2
ToppCelldistal-Hematologic-Proliferating_Macrophage-1|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

NCAPH FANCD2 BRCA2 RECQL4 MKI67 CLSPN

3.57e-0519813862b0716e900bce54ad1825d6dcdaf4ebf31f355c4
ToppCellCOVID-19_Severe-T/NK_proliferative|World / disease group, cell group and cell class

NCAPH FANCD2 BRCA2 RECQL4 MKI67 CLSPN

3.57e-05198138648045689d0969ff0a14eee7086b8e19b0d6b6065
ToppCellcycling_basal_cell|World / shred by cell class for turbinate

NCAPH FANCD2 BRCA2 RECQL4 MKI67 CLSPN

3.57e-051981386e86c1224f5b0890a50a25257628e90c790aae7cd
ToppCell(0)_NK_Dividing|World / Lung cell shreds - cell class (v4) and cell subclass (v4)

NCAPH FANCD2 BRCA2 RECQL4 MKI67 CLSPN

3.57e-0519813865ebb4965b723302152b42bfaf48bb77a57dd02c5
ToppCellmedial-Hematologic-Proliferating_Macrophage|medial / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

NCAPH FANCD2 BRCA2 RECQL4 MKI67 CLSPN

3.57e-051981386da6963184c32761c896a9b91a5321ad84b583736
ToppCellPBMC-Mild-Lymphocyte-T/NK-Other_T-T/NK_proliferative-|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

NCAPH FANCD2 BRCA2 RECQL4 MKI67 CLSPN

3.67e-05199138611c3d9fe811a4619347f47d2b0e94066e3085625
ToppCellMNPs-Dividing_Macrophages|MNPs / lung cells shred on cell class, cell subclass, sample id

NCAPH FANCD2 BRCA2 RECQL4 MKI67 CLSPN

3.67e-0519913865952980d0ece5d73f3e9f340c56a38b34d2f2309
ToppCellPBMC-Mild-Lymphocyte-T/NK-Other_T-T/NK_proliferative-|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

NCAPH FANCD2 BRCA2 RECQL4 MKI67 CLSPN

3.67e-05199138636c80907b2ec1cbcd1b4e841e6c02a4792591d74
ToppCellPBMC-Mild-Lymphocyte-T/NK-Other_T-T/NK_proliferative|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)

NCAPH FANCD2 BRCA2 RECQL4 MKI67 CLSPN

3.67e-051991386bf4c31902ae8358215245a2e11b5a2fe4ca1bc8c
ToppCellCOVID-19_Mild-Lymphoid_T/NK-T/NK_proliferative|COVID-19_Mild / Disease group, lineage and cell class

NCAPH FANCD2 BRCA2 RECQL4 MKI67 CLSPN

3.67e-051991386ddea0e5c1cb6a096ab8e09a8c3c37c1bff381d9c
ToppCellBiopsy_Control_(H.)-Epithelial-Proliferating_Epithelial_cells|Biopsy_Control_(H.) / Sample group, Lineage and Cell type

NCAPH FANCD2 BRCA2 RECQL4 MKI67 CLSPN

3.67e-0519913864fcf5bec207e4384fd73c5e8801a7e414e3ee7b0
ToppCellPBMC-Mild-Lymphocyte-T/NK-Other_T-T/NK_proliferative|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

NCAPH FANCD2 BRCA2 RECQL4 MKI67 CLSPN

3.67e-0519913867beb0e07a27fea94674f24eb61c381b0de38ed3e
ToppCellCOVID-19_Mild-T/NK_proliferative|COVID-19_Mild / Disease condition and Cell class

NCAPH FANCD2 BRCA2 RECQL4 MKI67 CLSPN

3.67e-0519913869f9a88d2b099646c1e1a7ee3f8d39cb1a2498ad7
ToppCellDividing_Macrophages|World / lung cells shred on cell class, cell subclass, sample id

NCAPH FANCD2 BRCA2 RECQL4 MKI67 CLSPN

3.67e-0519913865c755b6876e164dc847ef7c723f850f227cf3a87
ToppCellNon-neuronal|World / Primary Cells by Cluster

ADGRV1 BRCA2 PTPRZ1 MKI67 CLSPN LRRC17

3.67e-051991386165d9de6cedc79e13bb6fa244e8898a5dacc54ff
ToppCellParenchymal-10x3prime_v2-Epithelial-Epi_airway_basal-Dividing_Basal|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

NCAPH CRYM PTPRZ1 RECQL4 MKI67 CLSPN

3.67e-051991386f0c289523957258d16135c04679db379d43d28d9
ToppCelldistal-Hematologic-Proliferating_Macrophage|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

NCAPH FANCD2 BRCA2 RECQL4 MKI67 CLSPN

3.78e-0520013863835a8a9739b8cd5bf19c40765ef76907ac1ad38
ToppCellCOVID-19-COVID-19_Mild-Lymphocyte-T/NK-T/NK_proliferative|COVID-19_Mild / Disease, condition lineage and cell class

NCAPH FANCD2 BRCA2 RECQL4 MKI67 CLSPN

3.78e-0520013866126a3bbafe2110fba0c1c4493035df4e8193d22
ToppCelldistal-2-Hematologic-Proliferating_Macrophage|2 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

NCAPH FANCD2 BRCA2 RECQL4 MKI67 CLSPN

3.78e-0520013860cd3b01fb7f579e5abf000adb8ec8adc7cd779c4
ToppCellControl-Control-Lymphocyte-T/NK-T/NK_proliferative|Control / Disease, condition lineage and cell class

NCAPH FANCD2 BRCA2 RECQL4 MKI67 CLSPN

3.78e-0520013866cf63dd57f6bc0c42e7182322dd24ff9afbe9186
ToppCellBiopsy_IPF-Epithelial-Proliferating_Epithelial_cells|Biopsy_IPF / Sample group, Lineage and Cell type

NCAPH FANCD2 BRCA2 RECQL4 MKI67 CLSPN

3.78e-05200138663c5402f050fdb12abab3c8b7f33d4914ae26b9b
ToppCell356C-Lymphocytic-NK_cells-Proliferating_NK_cell|NK_cells / Donor, Lineage, Cell class and subclass (all cells)

NCAPH FANCD2 BRCA2 RECQL4 MKI67 CLSPN

3.78e-05200138697e47eb69d1d4cab45256acca9589837eb7817e7
ToppCellhealthy_donor-Lymphocytic-Proliferative_Lymphocyte|healthy_donor / Disease condition, Lineage, Cell class and subclass

NCAPH FANCD2 BRCA2 RECQL4 MKI67 CLSPN

3.78e-052001386e4eb915c29909cf8535a3603c68976545c05e54b
ToppCell3'_v3-lymph-node_spleen-Lymphocytic_B_plasma-Plasmablasts|lymph-node_spleen / Manually curated celltypes from each tissue

NCAPH PPIB AMIGO3 RECQL4 MKI67 CLSPN

3.78e-052001386b0d708715f09ec1f67fdef3b100a91c8ff2747a7
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

NCAPH FANCD2 BRCA2 RECQL4 MKI67 CLSPN

3.78e-05200138628c702449040ac15fe4e0c6340bb6f137e88539d
ToppCellSepsis-Bac-SEP-Lymphocyte-T/NK-T/NK_proliferative|Bac-SEP / Disease, condition lineage and cell class

NCAPH FANCD2 BRCA2 RECQL4 MKI67 CLSPN

3.78e-052001386a09b4e07b273880e94032b939ab191caaf6d656e
ToppCellhealthy_donor-Lymphocytic-Proliferative_Lymphocyte-|healthy_donor / Disease condition, Lineage, Cell class and subclass

NCAPH FANCD2 BRCA2 RECQL4 MKI67 CLSPN

3.78e-052001386415e7556b5ac45688e2c6c30a52bd40e0eb27c7d
ToppCelldistal-Hematologic-Proliferating_Macrophage-3|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

NCAPH FANCD2 BRCA2 RECQL4 MKI67 CLSPN

3.78e-0520013869c03a8da12d29618f72c429836c1d1bd84a78b12
ToppCell5'-GW_trimst-1.5-SmallIntestine-Neuronal-Glial_immature-ENCC/glia_Progenitor|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TMPRSS9 ADGRV1 RNF157 CRYM PTPRZ1 MMP17

3.78e-052001386de55100e98d3e9b8a74e37aebcd3afa2b0996527
ToppCell356C-Lymphocytic-NK_cells-Proliferating_NK_cell|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

NCAPH FANCD2 BRCA2 RECQL4 MKI67 CLSPN

3.78e-0520013865d11a2c0021805e78d97dc1638bf73ca1faede66
ToppCellCOVID_non-vent-Lymphocytic-Proliferative_Lymphocyte-|COVID_non-vent / Disease condition, Lineage, Cell class and subclass

NCAPH FANCD2 BRCA2 RECQL4 MKI67 CLSPN

3.78e-05200138604bf9e6a0fbd792b49eed63dabba5d6fafed8c07
ToppCellBiopsy_Other_PF-Immune-Proliferating_Macrophages|Biopsy_Other_PF / Sample group, Lineage and Cell type

NCAPH FANCD2 BRCA2 RECQL4 MKI67 CLSPN

3.78e-05200138661473e8613f39a92002d5b631e6bd563735566e4
ToppCellParenchymal-NucSeq-Epithelial-Epi_alveolar-Dividing_AT2|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

NCAPH FANCD2 BRCA2 RECQL4 MKI67 CLSPN

3.78e-052001386af3dc76b4507bf4edd265169f5dfbbb8a19eb394
ToppCellCOVID_non-vent-Lymphocytic-Proliferative_Lymphocyte|COVID_non-vent / Disease condition, Lineage, Cell class and subclass

NCAPH FANCD2 BRCA2 RECQL4 MKI67 CLSPN

3.78e-052001386f6b5320cdfe640a71e6e2df26f30d42e64b1c921
DrugThyroxine (L) [51-48-9]; Down 200; 5.2uM; MCF7; HT_HG-U133A

BIN1 SRC ITGA5 ECPAS STK11 ZBTB25 FGD1 HELZ PBXIP1

2.88e-0619813594150_DN
DrugBemegride [64-65-3]; Down 200; 25.8uM; PC3; HT_HG-U133A

ABHD2 MANEA INO80D MINDY3 VWA5A FGD1 CPLANE1 CNOT1 RUSF1

2.88e-0619813596668_DN
Drugdopamine hydrochloride; Down 200; 1uM; MCF7; HG-U133A

ABHD2 CHD9 ITGA5 STK11 MINDY3 LARP4B LLGL1 LRP3 ALDH4A1

3.01e-061991359491_DN
DiseaseX-23636 measurement

DMGDH SLC6A12

1.90e-0521292EFO_0800852
DiseaseMalignant neoplasm of breast

NID2 UBR4 SRC MANEA CUBN RFX2 LLGL1 BRCA2 SEMA5B MKI67 CLSPN DNAH9 NOS3 RUSF1 PADI3

7.36e-05107412915C0006142
DiseaseCiliopathies

ADGRV1 PKHD1 CC2D2A CPLANE1 DNAH11

1.25e-041101295C4277690
Diseasemucositis (biomarker_via_orthology)

MKI67 MUC2

1.88e-0451292DOID:0080178 (biomarker_via_orthology)
Diseasewhole-brain volume

CUBN DNAH11

1.88e-0451292EFO_0005089
Diseasesquamous cell carcinoma

SRC BRCA2 ANKRD11 DNAH11

2.16e-04671294EFO_0000707
Diseaseductal carcinoma in situ (is_implicated_in)

SRC BRCA2

3.93e-0471292DOID:0060074 (is_implicated_in)
Diseasecreatinine measurement

DMGDH CAND2 CHD9 ADGRV1 CUBN DUOX1 LARP4B PKHD1 ANKRD11 KIAA1755 TRPV4 ADGRL2 SLC23A1

4.31e-0499512913EFO_0004518
Diseasevisceral heterotaxy (implicated_via_orthology)

MEGF8 CC2D2A DNAH11

5.69e-04371293DOID:0050545 (implicated_via_orthology)
Diseasecolon cancer (biomarker_via_orthology)

MKI67 PLCG1 MUC2

6.65e-04391293DOID:219 (biomarker_via_orthology)
DiseaseAutosomal Recessive Polycystic Kidney Disease

SRC PKHD1

6.69e-0491292C0085548
Diseasemelanoma

DSC1 UBR4 CUBN STK11 BRCA2 ROS1

7.98e-042481296C0025202
DiseaseFanconi anemia (is_implicated_in)

FANCD2 BRCA2

8.34e-04101292DOID:13636 (is_implicated_in)
Diseasegrey matter volume measurement

CUBN SEMA5B ADGRL2

9.48e-04441293EFO_0005420
Diseasekidney cancer (implicated_via_orthology)

LLGL1 SCRIB

1.02e-03111292DOID:263 (implicated_via_orthology)
DiseaseBarrett's esophagus (is_marker_for)

MKI67 MUC2

1.02e-03111292DOID:9206 (is_marker_for)
Diseasenon-melanoma skin carcinoma

ATG7 CSMD2 ZNF469 BRCA2 C2CD4D ANKRD11

1.12e-032651296EFO_0009260
Diseasecancer (implicated_via_orthology)

CAND2 SRC TRIP12 LLGL1 BRCA2 SCRIB

1.19e-032681296DOID:162 (implicated_via_orthology)
Diseaseright ventricular stroke volume measurement

KIAA1755 NOS3

1.22e-03121292EFO_0021817
DiseaseBenign tumor of pancreas

STK11 BRCA2

1.43e-03131292C0347284
Diseaseurate measurement, bone density

RIPOR3 LARP4B HELZ2 PLXNA4 ANKRD11 KIAA1755 DNAH9 SLC23A1 DNAH11

1.64e-036191299EFO_0003923, EFO_0004531
DiseaseFanconi anemia

FANCD2 BRCA2

1.67e-03141292cv:C0015625
DiseaseCarcinoma, Granular Cell

STK11 MKI67 MUC2 NOS3

1.71e-031161294C0205644
DiseaseAdenocarcinoma, Tubular

STK11 MKI67 MUC2 NOS3

1.71e-031161294C0205645
DiseaseAdenocarcinoma, Oxyphilic

STK11 MKI67 MUC2 NOS3

1.71e-031161294C0205642
DiseaseCarcinoma, Cribriform

STK11 MKI67 MUC2 NOS3

1.71e-031161294C0205643
DiseaseAdenocarcinoma, Basal Cell

STK11 MKI67 MUC2 NOS3

1.71e-031161294C0205641
DiseaseAdenocarcinoma

STK11 MKI67 MUC2 NOS3

1.71e-031161294C0001418
Diseasecreatine kinase measurement

BIN1 CAND2 ROS1

2.22e-03591293EFO_0004534
Diseasebone mineral content measurement

MANEA ADGRV1 STMN4 LARP4B

2.59e-031301294EFO_0007621
DiseaseBone marrow hypocellularity

FANCD2 BRCA2

2.77e-03181292C1855710
Diseasecarcinoma (implicated_via_orthology)

SRC LLGL1 SCRIB

2.80e-03641293DOID:305 (implicated_via_orthology)
Diseaseovarian neoplasm

ATG7 STK11 BRCA2 MKI67

2.89e-031341294C0919267
DiseasePancreatic carcinoma

STK11 BRCA2

3.09e-03191292C0235974
DiseaseMalignant neoplasm of ovary

ATG7 STK11 BRCA2 MKI67

3.13e-031371294C1140680
DiseaseFamilial aplasia of the vermis

CC2D2A CPLANE1

3.42e-03201292cv:C0431399
Diseasebrain age measurement

DMGDH RNF157

3.42e-03201292EFO_0010602
Diseasebreast cancer (is_implicated_in)

FANCD2 BRCA2 MKI67 NOS3

4.32e-031501294DOID:1612 (is_implicated_in)

Protein segments in the cluster

PeptideGeneStartEntry
GPQDSPFEGGTFKLE

UBE2N

41

P61088
ETLNGLAQFPDTLPG

EPHA1

206

P21709
GLTAFLEVSFTEPPG

ANKRD11

1316

Q6UB99
VDFEGTNGVPLFPDL

CLSTN3

656

Q9BQT9
LTLGRFEASGPPTAF

CATSPERB

506

Q9H7T0
FEIFDGPSGQSPLLK

CSMD2

2411

Q7Z408
GGSTLLNLDFFGPVD

AFTPH

821

Q6ULP2
HLGFFEGSVLFPEPL

ABHD2

376

P08910
AFLEDGSPSPVLAFA

FAM117A

311

Q9C073
SLPFFAPLGLQGSIN

GSDMA

176

Q96QA5
AVTPDDIGPFNGSVL

ADGRV1

701

Q8WXG9
PVFLGLVGDLFPALD

DNAH11

2111

Q96DT5
FVPADGPLFGDTVTS

ALDH4A1

261

P30038
PNTEGFSRAALPFGL

ADGRL2

21

O95490
TAPPALDIFGDLFES

SNAP91

556

O60641
PEPEAFNTGFTTLLG

AMIGO3

376

Q86WK7
AFIPSSQRGFPDEGI

AMBRA1

906

Q9C0C7
PADGEVGSNVPFLLE

CC2D2B

591

Q6DHV5
FSDPLLGFEPRGTAI

DISP1

216

Q96F81
PLETALANFSSGPEG

CRYM

26

Q14894
DPPALFSGDALSVAG

HAGHL

126

Q6PII5
EFLLLGFSQEPGLQP

OR7A5

11

Q15622
ALSFQLPSRPGFDGA

LLGL1

116

Q15334
LFPGLFHDDGSELPQ

DUOX1

1166

Q9NRD9
AGNSPPLFTLDEQSG

DCHS1

726

Q96JQ0
LAAEGASSPFGLEPQ

DCHS1

1036

Q96JQ0
LGPFLQEFFPDQGSS

MINDY3

361

Q9H8M7
PASFILNGVPGLEDT

OR52N4

11

Q8NGI2
SIQLGDTPPFALGFN

KIAA0100

431

Q14667
IDPGSPFLELSQFAG

MCCC2

91

Q9HCC0
DISPFSGDGQPFKDI

MEPE

251

Q9NQ76
FTDEIAGSLPAFGPD

IMPG1

376

Q17R60
AGSLPAFGPDTQSEL

IMPG1

381

Q17R60
QGDGLSFLLDFLIPA

KIAA1755

41

Q5JYT7
SNGIEFIDPAAFLGL

LRRC17

301

Q8N6Y2
ILQEDGLSGFLPDPF

CD300H

116

A0A0K2S4Q6
ERGPGLLESPSIFNF

LARP4B

426

Q92615
GTTVLPFNPAAFGEI

ECPAS

581

Q5VYK3
NPVFEAFGPSGILEL

PLXNA4

1141

Q9HCM2
TAAPFLLTGFPGLEA

OR51B2

6

Q9Y5P1
GNPFKLFEIDPTSGV

PCDH7

786

O60245
FLSDGVLFSPLEFGN

MUC2

181

Q02817
PNGVKGLPDFASFSA

DECR2

276

Q9NUI1
LPSGCQAGLDFSQPF

DEFB105A

21

Q8NG35
AAGAFLSPPGLLAVF

MEGF8

231

Q7Z7M0
ASPDLFGAARGPSDL

LRP3

266

O75074
SLFTDGFCGLILNPP

KCNU1

561

A8MYU2
EPLLPTSESFGGNVF

MKI67

796

P46013
DLAGFKELFQTPGPS

MKI67

1101

P46013
ILAAGDSEITPGFPQ

PTPRZ1

1581

P23471
PSVFFLLGIPGLEQF

OR52P1

11

Q8NH57
VSGLDSFGNLEVSPP

PADI3

401

Q9ULW8
SFIDENPSGLPIGEA

HELZ

1481

P42694
PNTATFGAPFGLDLL

MANEA

31

Q5SRI9
LEIGGLEFPAAPFSG

NOS3

341

P29474
TDIGLPNGLTFDPFS

NID2

1271

Q14112
LSNAGLPPDAFRGSE

PODNL1

181

Q6PEZ8
GFNLDAEAPAVLSGP

ITGA5

41

P08648
GFLLDGFQGNPTTLE

QTRT2

216

Q9H974
EGELFLPELSGPFTH

CUBN

716

O60494
GLSDDAFVQPGPVSL

CHD9

21

Q3L8U1
GVQLPGLTFPDSVDD

GCC1

71

Q96CN9
GDPGLSKLQFAPFSS

ATG7

6

O95352
PFLPDTVSFGGICDL

CC2D2A

1336

Q9P2K1
QTLKDFISFGSGEPP

DOCK4

436

Q8N1I0
FPLPLSSLFSDGGNV

BRCA2

2801

P51587
AKTFSPGDGFPLLQF

CPLANE1

2216

Q9H799
GQDPFSFDLLGNPLE

DNAJB3

106

Q8WWF6
FFDGLGPPDLAARSL

C2CD4D

291

B7Z1M9
TNGVPPGFGKELFES

DMGDH

326

Q9UI17
SISGPGVDKEPFNLF

DSC1

171

Q08554
NLGDPSPFSNLLGAD

INO80D

896

Q53TQ3
LGTIFIQAFDDAPGL

DNAH9

526

Q9NYC9
TTFFKLPGGELNPGE

NUDT21

101

O43809
NTTFFDPAGGGDPIL

MT-CO1

216

P00395
LLSPGALAPEFFTDA

HELZ2

881

Q9BYK8
PGPFSEQASLLDLDF

BIN1

381

O00499
AFLQGLLGTEPAEAF

CAND2

501

O75155
AGELRGPVPSFAFSQ

PERM1

716

Q5SV97
PLLFSQDFAKDGGPV

FANCD2

701

Q9BXW9
VPELFTDPLFSKSGG

CROT

521

Q9UKG9
FDFGPLAAVPKTLFG

NUP88

241

Q99567
DFFPPTSELLEGGNQ

OR1P1

6

Q8NH06
SGLQAVFLPQGFPDS

RUSF1

71

Q96GQ5
FDAEILGFSTPPGRL

SYS1

51

Q8N2H4
LLFSVAFPVDGEPDA

VARS2

316

Q5ST30
PAAAEPKLFGGFNSS

SRC

56

P12931
EGLPAESPDSNFAGL

RNF157

566

Q96PX1
FFPNSDLSEGQLPAG

PRUNE2

521

Q8WUY3
VSDFSLPPGGIDAAF

MMP17

421

Q9ULZ9
EFPAPDLGSFLLQDG

RFX2

346

P48378
LGPSGQLAETPAEVF

RECQL4

456

O94761
PEGLLLPSEAAFGNS

KCP

1361

Q6ZWJ8
EFFLLGLSGDPELQP

OR7G3

11

Q8NG95
AQSPPTFGFLLDIDG

HDHD5

41

Q9BXW7
LDPQFVGPSDTSLGA

FGD1

56

P98174
NLSLDIGTEVFAPGP

NEU1

186

Q99519
AESGPGLAFIAFPKA

SLC6A12

356

P48065
SVFFLLLPGPSAADE

PPIB

21

P23284
ALFFSGNALLPGAEP

SELENOO

121

Q9BVL4
EGPNGPAFLAFARAL

CCT8L1P

431

A6NM43
GLSEEPELQPFLFGL

OR7A17

16

O14581
GLSEDPELQPFIFGL

OR7D2

16

Q96RA2
SLEGDPLPGASFSLN

PKHD1

1446

P08F94
PPEIANGLDTFSGFK

STK11

221

Q15831
GQSFEVILKPPSFDG

STMN4

61

Q9H169
DFSGNPLSRLPDGFT

SCRIB

111

Q14160
LAPNPVDDAGLLSFA

ABCC12

41

Q96J65
GPLALADGIPFFRSA

TRPT1

181

Q86TN4
DDLFVGPVGNSDLSP

NCAPH

576

Q15003
SPEPKTLFLGAGDFQ

CLSPN

846

Q9HAW4
DTPDATFLLRLFGPG

CNNM3

56

Q8NE01
GFLPTNDLSQPTGFL

CNOT1

1581

A5YKK6
PFGVPASILESNDLG

ZBTB25

266

P24278
PLGADIQGLDLFSFL

PIAS3

521

Q9Y6X2
AFFPGFPLALLVGTE

PIGV

86

Q9NUD9
PFLLQPTAAADADGL

TNRC18

1096

O15417
IEELLSPPFGGLVAF

VPS52

601

Q8N1B4
LPLSPAFFGEDGIFR

PBXIP1

636

Q96AQ6
PGAASALPELTFQGD

SPATA12

61

Q7Z6I5
GFLPLTFGPHASIEE

RIPOR3

426

Q96MK2
FTALFASLPDPILGG

SLC23A1

416

Q9UHI7
GSAGSVPENLNLFPE

SMAP2

236

Q8WU79
GSVFLPSLDFLADPD

SNX14

276

Q9Y5W7
LDGGNPFLDVPQALS

PSD2

496

Q9BQI7
LGLPGFFPSQEHEAT

TEX37

81

Q96LM6
PGGASEITFELPDNA

TMED7

31

Q9Y3B3
AFLGTPFLSGAEGQL

TMPRSS9

881

Q7Z410
IFPAKENGDLSPFSG

PLCG1

1211

P19174
LLAPGLFQGPAFEDA

PRRT4

741

C9JH25
SIPGHPLQLFVFTDG

VWA5A

381

O00534
LNSFGPGEFLSSDIG

ROS1

691

P08922
SFREFSGLKGAEAPP

ARHGAP31

1006

Q2M1Z3
PGARDFSQLALDPSG

SEMA5B

121

Q9P283
AGGSFDLRPFLTQPQ

nan

11

A8MWL6
FAPAIGFPQATGLSV

PTBP3

311

O95758
FLASPLPGDGITFQT

ZDHHC24

261

Q6UX98
FSRLAFSDDLGPLGP

ZC3H12D

346

A2A288
SLSPFPAALADGRGD

ZNF469

3526

Q96JG9
PSGGGDDFFLVLLDP

ZXDA

81

P98168
EGSGSEEKPFALFLP

TPRN

621

Q4KMQ1
SVEDLGLDFTLPGFP

TRIP12

1786

Q14669
NPSPLEALLAGAEGF

UBR4

2786

Q5T4S7
PGGEAFPLSSLANLF

TRPV4

26

Q9HBA0
PDFQPELSGAGSRLA

TXNL1

11

O43396
SQAATGPDFSFLPGL

FAM53A

61

Q6NSI3