Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	DNA-binding transcription factor activity, RNA polymerase II-specific	ZNF7 ZNF771 ZNF384 ZNF18 ZNF836 ZNF22 ZNF573 ZBTB16 ZNF211 ZNF562 ZNF33A ZNF43 ZNF570 ZNF180 ZNF197 ZNF184 ZNF480 ZNF76 ZSCAN2 ZNF841 ZNF225 ZNF30 ZNF112 ZNF519 ZNF454 ZBTB42 ZNF404 ZNF71	2.63e-13	1412	79	28	GO:0000981
GeneOntologyMolecularFunction	RNA polymerase II transcription regulatory region sequence-specific DNA binding	ZNF7 ZNF771 ZNF384 ZNF18 ZNF836 ZNF22 ZNF573 ZBTB16 ZNF211 ZNF562 ZNF33A ZNF43 ZNF570 ZNF180 ZNF197 ZNF184 ZNF480 ZNF76 ZSCAN2 CHD2 ZNF841 ZNF225 ZNF30 ZNF112 ZNF519 ZNF454 ZNF404 ZNF71	5.85e-13	1459	79	28	GO:0000977
GeneOntologyMolecularFunction	RNA polymerase II cis-regulatory region sequence-specific DNA binding	ZNF7 ZNF771 ZNF384 ZNF18 ZNF836 ZNF22 ZNF573 ZBTB16 ZNF211 ZNF562 ZNF33A ZNF43 ZNF570 ZNF197 ZNF184 ZNF480 ZNF76 ZSCAN2 CHD2 ZNF841 ZNF225 ZNF30 ZNF112 ZNF519 ZNF454 ZNF71	7.43e-13	1244	79	26	GO:0000978
GeneOntologyMolecularFunction	cis-regulatory region sequence-specific DNA binding	ZNF7 ZNF771 ZNF384 ZNF18 ZNF836 ZNF22 ZNF573 ZBTB16 ZNF211 ZNF562 ZNF33A ZNF43 ZNF570 ZNF197 ZNF184 ZNF480 ZNF76 ZSCAN2 CHD2 ZNF841 ZNF225 ZNF30 ZNF112 ZNF519 ZNF454 ZNF71	1.21e-12	1271	79	26	GO:0000987
GeneOntologyMolecularFunction	DNA-binding transcription activator activity, RNA polymerase II-specific	ZNF771 ZNF384 ZNF836 ZBTB16 ZNF33A ZNF43 ZNF197 ZNF76 ZSCAN2 ZNF841 ZNF225 ZNF112 ZNF519 ZNF71	3.69e-08	560	79	14	GO:0001228
GeneOntologyMolecularFunction	DNA-binding transcription activator activity	ZNF771 ZNF384 ZNF836 ZBTB16 ZNF33A ZNF43 ZNF197 ZNF76 ZSCAN2 ZNF841 ZNF225 ZNF112 ZNF519 ZNF71	4.21e-08	566	79	14	GO:0001216
GeneOntologyMolecularFunction	adenylate cyclase activity	ADCY4 ADCY2 ADCY7	4.66e-05	18	79	3	GO:0004016
GeneOntologyMolecularFunction	cyclase activity	ADCY4 ADCY2 ADCY7	1.14e-04	24	79	3	GO:0009975
GeneOntologyMolecularFunction	phosphorus-oxygen lyase activity	ADCY4 ADCY2 ADCY7	1.29e-04	25	79	3	GO:0016849
GeneOntologyBiologicalProcess	regulation of adenylate cyclase activity	ADCY4 P2RY13 GABBR2 ADCY2 ADCY7	2.90e-06	59	78	5	GO:0045761
GeneOntologyBiologicalProcess	regulation of cyclase activity	ADCY4 P2RY13 GABBR2 ADCY2 ADCY7	6.32e-06	69	78	5	GO:0031279
GeneOntologyBiologicalProcess	regulation of lyase activity	ADCY4 P2RY13 GABBR2 ADCY2 ADCY7	8.34e-06	73	78	5	GO:0051339
GeneOntologyBiologicalProcess	cAMP biosynthetic process	ADCY4 ADCY2 ADCY7	8.40e-06	11	78	3	GO:0006171
GeneOntologyBiologicalProcess	cyclic purine nucleotide metabolic process	ADCY4 PDE1A ADCY2 ADCY7	2.29e-05	44	78	4	GO:0052652
GeneOntologyBiologicalProcess	cyclic nucleotide metabolic process	ADCY4 PDE1A ADCY2 ADCY7	2.51e-05	45	78	4	GO:0009187
GeneOntologyBiologicalProcess	cyclic nucleotide biosynthetic process	ADCY4 ADCY2 ADCY7	8.72e-05	23	78	3	GO:0009190
GeneOntologyBiologicalProcess	cAMP metabolic process	ADCY4 ADCY2 ADCY7	1.13e-04	25	78	3	GO:0046058
GeneOntologyBiologicalProcess	positive regulation of transcription by RNA polymerase II	KDM3A ZNF384 KMT2C ZNF836 ZNF609 ZBTB16 ZNF33A ZNF43 ZNF197 ZNF76 ZNF841 ZNF225 ZNF112 ZFPM2 ZNF71	1.93e-04	1390	78	15	GO:0045944
GeneOntologyBiologicalProcess	activation of adenylate cyclase activity	ADCY4 ADCY2 ADCY7	2.86e-04	34	78	3	GO:0007190
GeneOntologyBiologicalProcess	adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway	ADCY4 GABBR2 ADCY2 ADCY7	3.18e-04	86	78	4	GO:0007193
GeneOntologyBiologicalProcess	positive regulation of adenylate cyclase activity	ADCY4 ADCY2 ADCY7	4.65e-04	40	78	3	GO:0045762
GeneOntologyCellularComponent	protein phosphatase type 2A complex	PPP2R2A PPP2R2C PPP2R2D	4.07e-05	18	79	3	GO:0000159
Domain	-	ZNF7 ZNF771 ZNF384 ZNF18 ZNF836 ZNF22 ZNF573 ZBTB16 ZNF211 ZNF562 ZNF33A ZNF43 ZNF570 ZNF180 ZNF197 ZNF184 ZIM2 ZNF480 ZNF76 ZSCAN2 ZNF841 ZNF225 ZNF30 ZNF112 ZNF519 ZNF235 ZNF454 ZBTB42 ZFPM2 ZNF404 ZNF71	3.26e-24	679	80	31	3.30.160.60
Domain	Znf_C2H2/integrase_DNA-bd	ZNF7 ZNF771 ZNF384 ZNF18 ZNF836 ZNF22 ZNF573 ZBTB16 ZNF211 ZNF562 ZNF33A ZNF43 ZNF570 ZNF180 ZNF197 ZNF184 ZIM2 ZNF480 ZNF76 ZSCAN2 ZNF841 ZNF225 ZNF30 ZNF112 ZNF519 ZNF235 ZNF454 ZBTB42 ZFPM2 ZNF404 ZNF71	6.26e-24	694	80	31	IPR013087
Domain	ZINC_FINGER_C2H2_2	ZNF7 ZNF771 ZNF384 ZNF18 ZNF836 ZNF22 ZNF609 ZNF573 ZBTB16 ZNF211 ZNF562 ZNF33A ZNF43 ZNF570 ZNF180 ZNF197 ZNF184 ZIM2 ZNF480 ZNF76 ZSCAN2 ZNF841 ZNF225 ZNF30 ZNF112 ZNF519 ZNF235 ZNF454 ZBTB42 ZFPM2 ZNF404 ZNF71	1.06e-23	775	80	32	PS50157
Domain	ZINC_FINGER_C2H2_1	ZNF7 ZNF771 ZNF384 ZNF18 ZNF836 ZNF22 ZNF609 ZNF573 ZBTB16 ZNF211 ZNF562 ZNF33A ZNF43 ZNF570 ZNF180 ZNF197 ZNF184 ZIM2 ZNF480 ZNF76 ZSCAN2 ZNF841 ZNF225 ZNF30 ZNF112 ZNF519 ZNF235 ZNF454 ZBTB42 ZFPM2 ZNF404 ZNF71	1.14e-23	777	80	32	PS00028
Domain	Znf_C2H2-like	ZNF7 ZNF771 ZNF384 ZNF18 ZNF836 ZNF22 ZNF609 ZNF573 ZBTB16 ZNF211 ZNF562 ZNF33A ZNF43 ZNF570 ZNF180 ZNF197 ZNF184 ZIM2 ZNF480 ZNF76 ZSCAN2 ZNF841 ZNF225 ZNF30 ZNF112 ZNF519 ZNF235 ZNF454 ZBTB42 ZFPM2 ZNF404 ZNF71	2.40e-23	796	80	32	IPR015880
Domain	Znf_C2H2	ZNF7 ZNF771 ZNF384 ZNF18 ZNF836 ZNF22 ZNF609 ZNF573 ZBTB16 ZNF211 ZNF562 ZNF33A ZNF43 ZNF570 ZNF180 ZNF197 ZNF184 ZIM2 ZNF480 ZNF76 ZSCAN2 ZNF841 ZNF225 ZNF30 ZNF112 ZNF519 ZNF235 ZNF454 ZBTB42 ZFPM2 ZNF404 ZNF71	3.38e-23	805	80	32	IPR007087
Domain	ZnF_C2H2	ZNF7 ZNF771 ZNF384 ZNF18 ZNF836 ZNF22 ZNF609 ZNF573 ZBTB16 ZNF211 ZNF562 ZNF33A ZNF43 ZNF570 ZNF180 ZNF197 ZNF184 ZIM2 ZNF480 ZNF76 ZSCAN2 ZNF841 ZNF225 ZNF30 ZNF112 ZNF519 ZNF235 ZNF454 ZBTB42 ZFPM2 ZNF404 ZNF71	3.79e-23	808	80	32	SM00355
Domain	zf-C2H2	ZNF7 ZNF771 ZNF384 ZNF18 ZNF836 ZNF22 ZNF573 ZBTB16 ZNF211 ZNF562 ZNF33A ZNF43 ZNF570 ZNF180 ZNF197 ZNF184 ZIM2 ZNF480 ZNF76 ZSCAN2 ZNF841 ZNF225 ZNF30 ZNF112 ZNF519 ZNF235 ZNF454 ZFPM2 ZNF404 ZNF71	1.01e-22	693	80	30	PF00096
Domain	KRAB	ZNF7 ZNF18 ZNF836 ZNF573 ZNF211 ZNF562 ZNF33A ZNF43 ZNF570 ZNF180 ZNF197 ZNF184 ZIM2 ZNF480 ZNF225 ZNF30 ZNF112 ZNF519 ZNF235 ZNF454 ZNF404	1.73e-18	358	80	21	PS50805
Domain	KRAB	ZNF7 ZNF18 ZNF836 ZNF573 ZNF211 ZNF562 ZNF33A ZNF43 ZNF570 ZNF180 ZNF197 ZNF184 ZIM2 ZNF480 ZNF225 ZNF30 ZNF112 ZNF519 ZNF235 ZNF454 ZNF404	1.73e-18	358	80	21	PF01352
Domain	KRAB	ZNF7 ZNF18 ZNF836 ZNF573 ZNF211 ZNF562 ZNF33A ZNF43 ZNF570 ZNF180 ZNF197 ZNF184 ZIM2 ZNF480 ZNF225 ZNF30 ZNF112 ZNF519 ZNF235 ZNF454 ZNF404	3.21e-18	369	80	21	SM00349
Domain	KRAB	ZNF7 ZNF18 ZNF836 ZNF573 ZNF211 ZNF562 ZNF33A ZNF43 ZNF570 ZNF180 ZNF197 ZNF184 ZIM2 ZNF480 ZNF225 ZNF30 ZNF112 ZNF519 ZNF235 ZNF454 ZNF404	3.40e-18	370	80	21	IPR001909
Domain	zf-C2H2_6	ZNF771 ZNF384 ZNF836 ZNF573 ZBTB16 ZNF211 ZNF562 ZNF43 ZNF570 ZNF197 ZNF184 ZNF480 ZSCAN2 ZNF841 ZNF225 ZNF30 ZNF404 ZNF71	9.81e-16	314	80	18	PF13912
Domain	PP2A_PR55	PPP2R2A PPP2R2C PPP2R2D	3.02e-07	4	80	3	IPR000009
Domain	PP2A_PR55_CS	PPP2R2A PPP2R2C PPP2R2D	3.02e-07	4	80	3	IPR018067
Domain	PR55_2	PPP2R2A PPP2R2C PPP2R2D	3.02e-07	4	80	3	PS01025
Domain	PR55_1	PPP2R2A PPP2R2C PPP2R2D	3.02e-07	4	80	3	PS01024
Domain	Adcy_conserved_dom	ADCY4 ADCY2 ADCY7	1.50e-06	6	80	3	IPR009398
Domain	DUF1053	ADCY4 ADCY2 ADCY7	1.50e-06	6	80	3	PF06327
Domain	AC_N	ADCY4 ADCY2 ADCY7	4.17e-06	8	80	3	IPR032628
Domain	Adcy	ADCY4 ADCY2 ADCY7	4.17e-06	8	80	3	IPR030672
Domain	AC_N	ADCY4 ADCY2 ADCY7	4.17e-06	8	80	3	PF16214
Domain	A/G_cyclase_CS	ADCY4 ADCY2 ADCY7	4.93e-05	17	80	3	IPR018297
Domain	Nucleotide_cyclase	ADCY4 ADCY2 ADCY7	5.90e-05	18	80	3	IPR029787
Domain	-	ADCY4 ADCY2 ADCY7	5.90e-05	18	80	3	3.30.70.1230
Domain	GUANYLATE_CYCLASE_1	ADCY4 ADCY2 ADCY7	6.98e-05	19	80	3	PS00452
Domain	Guanylate_cyc	ADCY4 ADCY2 ADCY7	6.98e-05	19	80	3	PF00211
Domain	GUANYLATE_CYCLASE_2	ADCY4 ADCY2 ADCY7	6.98e-05	19	80	3	PS50125
Domain	A/G_cyclase	ADCY4 ADCY2 ADCY7	6.98e-05	19	80	3	IPR001054
Domain	CYCc	ADCY4 ADCY2 ADCY7	6.98e-05	19	80	3	SM00044
Domain	SCAN	ZNF18 ZNF197 ZSCAN2	1.78e-03	56	80	3	SM00431
Domain	SCAN_BOX	ZNF18 ZNF197 ZSCAN2	1.97e-03	58	80	3	PS50804
Domain	SCAN	ZNF18 ZNF197 ZSCAN2	1.97e-03	58	80	3	PF02023
Domain	SCAN_dom	ZNF18 ZNF197 ZSCAN2	1.97e-03	58	80	3	IPR003309
Domain	Retrov_capsid_C	ZNF18 ZNF197 ZSCAN2	2.07e-03	59	80	3	IPR008916
Domain	zf-RanBP	TAB2 TAF15	3.96e-03	22	80	2	PF00641
Domain	ZnF_RBZ	TAB2 TAF15	4.32e-03	23	80	2	SM00547
Domain	ZF_RANBP2_2	TAB2 TAF15	4.32e-03	23	80	2	PS50199
Domain	ZF_RANBP2_1	TAB2 TAF15	4.70e-03	24	80	2	PS01358
Domain	Znf_RanBP2	TAB2 TAF15	5.10e-03	25	80	2	IPR001876
Domain	-	PAPPA2 CELSR2 ADGRD1	7.89e-03	95	80	3	2.60.120.200
Pathway	REACTOME_RNA_POLYMERASE_II_TRANSCRIPTION	FANCD2 ZNF771 KMT2C ZNF18 ZNF573 ZNF211 ZNF562 ZNF33A ZNF43 ZNF570 ZNF180 ZNF197 ZNF184 ZIM2 ZNF480 TAF15 ZNF225 ZNF30 ZNF112 ZNF519 ZNF235 ZNF454 ZNF71 BID	2.88e-09	1387	64	24	M734
Pathway	REACTOME_CA_DEPENDENT_EVENTS	ADCY4 PDE1A ADCY2 ADCY7	5.36e-06	26	64	4	MM14495
Pathway	REACTOME_ADENYLATE_CYCLASE_ACTIVATING_PATHWAY	ADCY4 ADCY2 ADCY7	1.05e-05	10	64	3	M19522
Pathway	REACTOME_ADENYLATE_CYCLASE_ACTIVATING_PATHWAY	ADCY4 ADCY2 ADCY7	1.05e-05	10	64	3	MM14668
Pathway	KEGG_MEDICUS_REFERENCE_ADRB3_UCP1_SIGNALING_PATHWAY	KDM3A ADCY4 ADCY2 ADCY7	1.82e-05	35	64	4	M47969
Pathway	REACTOME_CA_DEPENDENT_EVENTS	ADCY4 PDE1A ADCY2 ADCY7	2.28e-05	37	64	4	M749
Pathway	REACTOME_G_PROTEIN_MEDIATED_EVENTS	ADCY4 PDE1A ADCY2 ADCY7	2.82e-05	39	64	4	MM14496
Pathway	REACTOME_ADENYLATE_CYCLASE_INHIBITORY_PATHWAY	ADCY4 ADCY2 ADCY7	3.13e-05	14	64	3	MM14669
Pathway	REACTOME_ADENYLATE_CYCLASE_INHIBITORY_PATHWAY	ADCY4 ADCY2 ADCY7	3.13e-05	14	64	3	M750
Pathway	REACTOME_DAG_AND_IP3_SIGNALING	ADCY4 PDE1A ADCY2 ADCY7	3.45e-05	41	64	4	M512
Pathway	KEGG_MEDICUS_REFERENCE_EP_NE_ADRB_CAMP_SIGNALING_PATHWAY	ADCY4 ADCY2 ADCY7	3.91e-05	15	64	3	M47794
Pathway	PID_LPA4_PATHWAY	ADCY4 ADCY2 ADCY7	3.91e-05	15	64	3	M56
Pathway	KEGG_MEDICUS_REFERENCE_PTH_PTH1R_PKA_SIGNALING_PATHWAY	ADCY4 ADCY2 ADCY7	3.91e-05	15	64	3	M47504
Pathway	REACTOME_GABA_B_RECEPTOR_ACTIVATION	ADCY4 GABBR2 ADCY2 ADCY7	4.17e-05	43	64	4	M954
Pathway	REACTOME_GABA_B_RECEPTOR_ACTIVATION	ADCY4 GABBR2 ADCY2 ADCY7	4.58e-05	44	64	4	MM15709
Pathway	WP_MAJOR_RECEPTORS_TARGETED_BY_EPINEPHRINE_AND_NOREPINEPHRINE	ADCY4 ADCY2 ADCY7	4.79e-05	16	64	3	M39849
Pathway	KEGG_MEDICUS_REFERENCE_LHCGR_GNAS_PKA_SIGNALING_PATHWAY	ADCY4 ADCY2 ADCY7	4.79e-05	16	64	3	M47645
Pathway	KEGG_MEDICUS_REFERENCE_FSHR_GNAS_PKA_SIGNALING_PATHWAY	ADCY4 ADCY2 ADCY7	4.79e-05	16	64	3	M47650
Pathway	REACTOME_PKA_MEDIATED_PHOSPHORYLATION_OF_CREB	ADCY4 ADCY2 ADCY7	4.79e-05	16	64	3	MM14492
Pathway	REACTOME_PKA_ACTIVATION_IN_GLUCAGON_SIGNALLING	ADCY4 ADCY2 ADCY7	5.80e-05	17	64	3	M26995
Pathway	KEGG_MEDICUS_REFERENCE_CX3CR1_GNAI_AC_PKA_SIGNALING_PATHWAY	ADCY4 ADCY2 ADCY7	5.80e-05	17	64	3	M47544
Pathway	KEGG_MEDICUS_REFERENCE_PP2A_AKT_SIGNALING_PATHWAY	PPP2R2A PPP2R2C PPP2R2D	8.21e-05	19	64	3	M47525
Pathway	REACTOME_PKA_MEDIATED_PHOSPHORYLATION_OF_CREB	ADCY4 ADCY2 ADCY7	9.63e-05	20	64	3	M759
Pathway	REACTOME_G_PROTEIN_MEDIATED_EVENTS	ADCY4 PDE1A ADCY2 ADCY7	1.03e-04	54	64	4	M26911
Pathway	WP_PHOSPHODIESTERASES_IN_NEURONAL_FUNCTION	ADCY4 PDE1A ADCY2 ADCY7	1.11e-04	55	64	4	M39763
Pathway	KEGG_MEDICUS_REFERENCE_CD80_CD86_CTLA4_PP2A_SIGNALING_PATHWAY	PPP2R2A PPP2R2C PPP2R2D	1.29e-04	22	64	3	M47919
Pathway	REACTOME_GABA_RECEPTOR_ACTIVATION	ADCY4 GABBR2 ADCY2 ADCY7	1.56e-04	60	64	4	M976
Pathway	REACTOME_GABA_RECEPTOR_ACTIVATION	ADCY4 GABBR2 ADCY2 ADCY7	1.56e-04	60	64	4	MM15708
Pathway	KEGG_MEDICUS_VARIANT_MUTATION_ACTIVATED_GNAS_TO_CRHR_PKA_ACTH_SIGNALING_PATHWAY	ADCY4 ADCY2 ADCY7	1.69e-04	24	64	3	M47520
Pathway	KEGG_MEDICUS_PATHOGEN_HCMV_UL33_TO_GNAI_AC_PKA_SIGNALING_PATHWAY	ADCY4 ADCY2 ADCY7	2.15e-04	26	64	3	M47553
Pathway	KEGG_MEDICUS_REFERENCE_CRHR_PKA_ACTH_SIGNALING_PATHWAY	ADCY4 ADCY2 ADCY7	2.42e-04	27	64	3	M47518
Pathway	KEGG_MEDICUS_VARIANT_MUTATION_INACTIVATED_RASD1_TO_CRHR_PKA_ACTH_SIGNALING_PATHWAY	ADCY4 ADCY2 ADCY7	2.42e-04	27	64	3	M47519
Pathway	KEGG_MEDICUS_REFERENCE_GHRHR_PKA_GH_SIGNALING_PATHWAY	ADCY4 ADCY2 ADCY7	2.70e-04	28	64	3	M47647
Pathway	REACTOME_OPIOID_SIGNALLING	ADCY4 PDE1A ADCY2 ADCY7	2.99e-04	71	64	4	MM14491
Pathway	KEGG_MEDICUS_VARIANT_MUTATION_ACTIVATED_GNAS_TO_ACTH_CORTISOL_SIGNALING_PATHWAY	ADCY4 ADCY2 ADCY7	3.00e-04	29	64	3	M47515
Pathway	KEGG_MEDICUS_REFERENCE_TSH_TG_SIGNALING_PATHWAY	ADCY4 ADCY2 ADCY7	3.00e-04	29	64	3	M47627
Pathway	KEGG_MEDICUS_VARIANT_CYP11B1_CYP11B2_FUSION_TO_ACTH_CORTISOL_SIGNALING_PATHWAY	ADCY4 ADCY2 ADCY7	3.66e-04	31	64	3	M47507
Pathway	KEGG_MEDICUS_REFERENCE_ACTH_CORTISOL_SIGNALING_PATHWAY	ADCY4 ADCY2 ADCY7	4.03e-04	32	64	3	M47506
Pathway	REACTOME_G_ALPHA_Z_SIGNALLING_EVENTS	ADCY4 ADCY2 ADCY7	4.42e-04	33	64	3	MM15058
Pathway	REACTOME_GLUCAGON_SIGNALING_IN_METABOLIC_REGULATION	ADCY4 ADCY2 ADCY7	4.42e-04	33	64	3	M11575
Pathway	REACTOME_REGULATION_OF_ENDOGENOUS_RETROELEMENTS	ZNF33A ZNF30 ZNF519 ZNF454 TASOR	4.57e-04	142	64	5	M48257
Pathway	REACTOME_OPIOID_SIGNALLING	ADCY4 PDE1A ADCY2 ADCY7	7.37e-04	90	64	4	M6467
Pathway	WP_G_PROTEIN_SIGNALING_PATHWAYS	ADCY4 PDE1A ADCY2 ADCY7	7.37e-04	90	64	4	MM15882
Pathway	WP_G_PROTEIN_SIGNALING	ADCY4 PDE1A ADCY2 ADCY7	7.68e-04	91	64	4	M39426
Pathway	REACTOME_ADORA2B_MEDIATED_ANTI_INFLAMMATORY_CYTOKINES_PRODUCTION	ADCY4 ADCY2 ADCY7	9.68e-04	43	64	3	M29837
Pathway	REACTOME_VASOPRESSIN_REGULATES_RENAL_WATER_HOMEOSTASIS_VIA_AQUAPORINS	ADCY4 ADCY2 ADCY7	9.68e-04	43	64	3	M933
Pathway	REACTOME_EPIGENETIC_REGULATION_OF_GENE_EXPRESSION	KMT2C ZNF33A ZNF30 ZNF519 ZNF454 TASOR	1.01e-03	254	64	6	M27131
Pathway	REACTOME_GPER1_SIGNALING	ADCY4 ADCY2 ADCY7	1.11e-03	45	64	3	M45008
Pathway	WP_ENVELOPE_PROTEINS_AND_THEIR_POTENTIAL_ROLES_IN_EDMD_PHYSIOPATHOLOGY	ADCY4 ADCY2 ADCY7	1.18e-03	46	64	3	M39828
Pathway	REACTOME_G_ALPHA_Z_SIGNALLING_EVENTS	ADCY4 ADCY2 ADCY7	1.33e-03	48	64	3	M10775
Pathway	REACTOME_REGULATION_OF_ENDOGENOUS_RETROELEMENTS_BY_KRAB_ZFP_PROTEINS	ZNF33A ZNF30 ZNF519 ZNF454	1.41e-03	107	64	4	M48260
Pathway	WP_THERMOGENESIS	KDM3A ADCY4 ADCY2 ADCY7	1.45e-03	108	64	4	M39746
Pathway	REACTOME_AQUAPORIN_MEDIATED_TRANSPORT	ADCY4 ADCY2 ADCY7	1.68e-03	52	64	3	M920
Pathway	REACTOME_G_ALPHA_I_SIGNALLING_EVENTS	ADCY4 PDE1A P2RY13 GABBR2 ADCY2 ADCY7	1.95e-03	289	64	6	MM15057
Pathway	REACTOME_GENERIC_TRANSCRIPTION_PATHWAY	ZNF18 ZNF836 ZNF43 ZNF180 ZNF184 TAF15 ZNF112 ZNF519 ZNF235 ZNF454	2.27e-03	768	64	10	MM14851
Pathway	PID_ENDOTHELIN_PATHWAY	ADCY4 ADCY2 ADCY7	2.92e-03	63	64	3	M8
Pathway	REACTOME_G_ALPHA_I_SIGNALLING_EVENTS	ADCY4 PDE1A P2RY13 GABBR2 ADCY2 ADCY7	2.95e-03	314	64	6	M600
Pathway	PID_LYSOPHOSPHOLIPID_PATHWAY	ADCY4 ADCY2 ADCY7	3.19e-03	65	64	3	M15
Pathway	REACTOME_SIGNALING_BY_HEDGEHOG	SEL1L ADCY4 ADCY2 ADCY7	3.46e-03	137	64	4	MM15182
Pathway	REACTOME_NEUROTRANSMITTER_RECEPTORS_AND_POSTSYNAPTIC_SIGNAL_TRANSMISSION	ADCY4 GABBR2 ADCY2 ADCY7	4.13e-03	144	64	4	MM14501
Pathway	REACTOME_SIGNALING_BY_HEDGEHOG	SEL1L ADCY4 ADCY2 ADCY7	4.77e-03	150	64	4	M27440
Pubmed	Acetylation-Mimic Mutation of TRIM28-Lys304 to Gln Attenuates the Interaction with KRAB-Zinc-Finger Proteins and Affects Gene Expression in Leukemic K562 Cells.	ZNF7 ZNF22 ZNF211 ZNF562 ZNF33A ZNF197 ZNF184 ZNF480 ZNF841 ZNF235	1.36e-11	181	80	10	37372979
Pubmed	Differential expansion of zinc-finger transcription factor loci in homologous human and mouse gene clusters.	ZNF180 ZNF225 ZNF112 ZNF235 ZNF404	8.56e-10	20	80	5	12743021
Pubmed	Multiple genes encoding zinc finger domains are expressed in human T cells.	ZNF7 ZNF18 ZNF22 ZNF43 ZNF30	9.20e-09	31	80	5	2288909
Pubmed	Twenty-seven nonoverlapping zinc finger cDNAs from human T cells map to nine different chromosomes with apparent clustering.	ZNF18 ZNF22 ZNF33A ZNF43	2.55e-08	14	80	4	2014798
Pubmed	HSF1 transcriptional activity is modulated by IER5 and PP2A/B55.	PPP2R2A PPP2R2C PPP2R2D	4.07e-07	7	80	3	25816751
Pubmed	Coexistence within one cell of microvillous and ciliary phototransductions across M1- through M6-IpRGCs.	ADCY4 ADCY2 ADCY7	4.07e-07	7	80	3	38109525
Pubmed	Role of the calcium modulated cyclases in the development of the retinal projections.	ADCY4 ADCY2 ADCY7	9.75e-07	9	80	3	17229090
Pubmed	Akt-dependent Pp2a activity is required for epidermal barrier formation during late embryonic development.	PPP2R2A PPP2R2C PPP2R2D	9.75e-07	9	80	3	19762425
Pubmed	Crystal structure of the catalytic domains of adenylyl cyclase in a complex with Gsalpha.GTPgammaS.	ADCY4 ADCY2 ADCY7	9.75e-07	9	80	3	9417641
Pubmed	Characterization of the human adenylyl cyclase gene family: cDNA, gene structure, and tissue distribution of the nine isoforms.	ADCY4 ADCY2 ADCY7	9.75e-07	9	80	3	12503609
Pubmed	Purification and characterization of a soluble form of mammalian adenylyl cyclase.	ADCY4 ADCY2 ADCY7	1.39e-06	10	80	3	8663304
Pubmed	Mechanism of human immunodeficiency virus-induced complement expression in astrocytes and neurons.	ADCY4 ADCY2 ADCY7	1.39e-06	10	80	3	11884542
Pubmed	Comprehensive analysis of the expression patterns of the adenylate cyclase gene family in the developing and adult mouse brain.	ADCY4 ADCY2 ADCY7	1.39e-06	10	80	3	16615126
Pubmed	Involvement of adenylate cyclase and p70(S6)-kinase activation in IL-10 up-regulation in human monocytes by gp41 envelope protein of human immunodeficiency virus type 1.	ADCY4 ADCY2 ADCY7	1.91e-06	11	80	3	10089566
Pubmed	gp120- and TNF-alpha-induced modulation of human B cell function: proliferation, cyclic AMP generation, Ig production, and B-cell receptor expression.	ADCY4 ADCY2 ADCY7	1.91e-06	11	80	3	10808179
Pubmed	Human immunodeficiency virus type 1 Tat protein decreases cyclic AMP synthesis in rat microglia cultures.	ADCY4 ADCY2 ADCY7	1.91e-06	11	80	3	11299302
Pubmed	Expression of adenylyl cyclase mRNAs in the denervated and in the developing mouse skeletal muscle.	ADCY4 ADCY2 ADCY7	2.54e-06	12	80	3	9611134
Pubmed	HIV-1 envelope protein gp41 modulates expression of interleukin-10 and chemokine receptors on monocytes, astrocytes and neurones.	ADCY4 ADCY2 ADCY7	2.54e-06	12	80	3	10807185
Pubmed	Isoforms of mammalian adenylyl cyclase: multiplicities of signaling.	ADCY4 ADCY2 ADCY7	4.19e-06	14	80	3	14993377
Pubmed	Regulation and immunohistochemical localization of betagamma-stimulated adenylyl cyclases in mouse hippocampus.	ADCY4 ADCY2	5.23e-06	2	80	2	9870949
Pubmed	TAF15 and the leukemia-associated fusion protein TAF15-CIZ/NMP4 are cleaved by caspases-3 and -7.	ZNF384 TAF15	5.23e-06	2	80	2	19426707
Pubmed	Two highly related regulatory subunits of PP2A exert opposite effects on TGF-beta/Activin/Nodal signalling.	PPP2R2A PPP2R2D	5.23e-06	2	80	2	18697906
Pubmed	Identification of the TAF15-ZNF384 fusion gene in two new cases of acute lymphoblastic leukemia with a t(12;17)(p13;q12).	ZNF384 TAF15	5.23e-06	2	80	2	21504714
Pubmed	cAMP-dependent protein kinase: framework for a diverse family of regulatory enzymes.	ADCY4 ADCY2 ADCY7	5.23e-06	15	80	3	2165385
Pubmed	Molecular characterization of the ankle-link complex in cochlear hair cells and its role in the hair bundle functioning.	ADCY4 ADCY2 ADCY7	6.42e-06	16	80	3	17567809
Pubmed	A census of human transcription factors: function, expression and evolution.	ZNF7 THAP2 ZNF384 ZNF22 ZNF43 ZNF180 ZNF197 ZNF76 ZSCAN2 ZNF30 ZFPM2	7.34e-06	908	80	11	19274049
Pubmed	Ppp2r2a Knockout Mice Reveal That Protein Phosphatase 2A Regulatory Subunit, PP2A-B55α, Is an Essential Regulator of Neuronal and Epidermal Embryonic Development.	PPP2R2A PPP2R2C PPP2R2D	1.11e-05	19	80	3	32582689
Pubmed	Expression of KIF3C kinesin during neural development and in vitro neuronal differentiation.	KIF3B KIF3C	1.57e-05	3	80	2	11331403
Pubmed	Kinesin-2 KIF3AC and KIF3AB Can Drive Long-Range Transport along Microtubules.	KIF3B KIF3C	1.57e-05	3	80	2	26445448
Pubmed	Heterodimerization of Kinesin-2 KIF3AB Modulates Entry into the Processive Run.	KIF3B KIF3C	1.57e-05	3	80	2	27637334
Pubmed	Brain protein phosphatase 2A: developmental regulation and distinct cellular and subcellular localization by B subunits.	PPP2R2A PPP2R2C	1.57e-05	3	80	2	9514514
Pubmed	Recurrent rearrangement of the Ewing's sarcoma gene, EWSR1, or its homologue, TAF15, with the transcription factor CIZ/NMP4 in acute leukemia.	ZNF384 TAF15	1.57e-05	3	80	2	12359745
Pubmed	Kinesin-2 and photoreceptor cell death: requirement of motor subunits.	KIF3B KIF3C	1.57e-05	3	80	2	16337628
Pubmed	Characterization and mapping of human genes encoding zinc finger proteins.	ZNF7 ZNF22 ZNF71	1.75e-05	22	80	3	1946370
Pubmed	Disrupted in Schizophrenia 1 Interactome: evidence for the close connectivity of risk genes and a potential synaptic basis for schizophrenia.	ZNF211 ZNF197 TAB2 CNKSR2 KIF3C	2.67e-05	151	80	5	17043677
Pubmed	Sequence comparison of human and mouse genes reveals a homologous block structure in the promoter regions.	SEL1L THAP2 ZNF384 KMT2C ZNF573 ZNF562 ZNF570 ZNF180 CNKSR2 ATP13A3 ADCY7 ZNF71	3.87e-05	1293	80	12	15342556
Pubmed	Glucagon and regulation of glucose metabolism.	ADCY4 ADCY2 ADCY7	5.03e-05	31	80	3	12626323
Pubmed	Mammalian adenylyl cyclase family members are randomly located on different chromosomes.	ADCY4 ADCY2	5.20e-05	5	80	2	7959689
Pubmed	Human bronchial smooth muscle cells express adenylyl cyclase isoforms 2, 4, and 6 in distinct membrane microdomains.	ADCY4 ADCY2	5.20e-05	5	80	2	21228062
Pubmed	Activation of protein phosphatase-2A1 by HIV-1 Vpr cell death causing peptide in intact CD(4+) T cells and in vitro.	PPP2R2A PPP2R2C	5.20e-05	5	80	2	15578586
Pubmed	H3K9 Demethylases JMJD1A and JMJD1B Control Prospermatogonia to Spermatogonia Transition in Mouse Germline.	KDM3A ZBTB16	7.79e-05	6	80	2	32679061
Pubmed	Mapping of adenylyl cyclase genes type I, II, III, IV, V, and VI in mouse.	ADCY4 ADCY2	7.79e-05	6	80	2	7766992
Pubmed	Protein phosphatase 2A (PP2A) holoenzymes regulate death-associated protein kinase (DAPK) in ceramide-induced anoikis.	PPP2R2A PPP2R2D	7.79e-05	6	80	2	20220139
Pubmed	Expression and regulation of adenylyl cyclase isoforms in the human adrenal gland.	ADCY4 ADCY2	7.79e-05	6	80	2	11549699
Pubmed	Differential expression of adenylyl cyclase mRNAs in lacrimal glands of NZB/NZW and NOD pre-autoimmune mice.	ADCY4 ADCY2	1.09e-04	7	80	2	12613887
Pubmed	A GO catalogue of human DNA-binding transcription factors.	ZNF22 ZIM2 ZNF235	1.26e-04	42	80	3	34673265
Pubmed	Type 2A protein phosphatase, the complex regulator of numerous signaling pathways.	PPP2R2A PPP2R2C	1.45e-04	8	80	2	11007961
Pubmed	The role of Vpr in HIV-1 pathogenesis.	PPP2R2A PPP2R2C	1.45e-04	8	80	2	15638722
Pubmed	A PP2A phosphatase high density interaction network identifies a novel striatin-interacting phosphatase and kinase complex linked to the cerebral cavernous malformation 3 (CCM3) protein.	PPP2R2A PPP2R2C PPP2R2D	1.66e-04	46	80	3	18782753
Pubmed	Rapid and efficient cloning of cDNAs encoding Krüppel-like zinc finger proteins by degenerate PCR.	ZNF7 ZNF836 ZNF43	2.00e-04	49	80	3	9630514
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	KDM3A KMT2C PPP2R2A ZNF609 PPP2R2D NFASC ZZEF1	2.21e-04	529	80	7	14621295
Pubmed	Interleukin-32α modulates promyelocytic leukemia zinc finger gene activity by inhibiting protein kinase Cɛ-dependent sumoylation.	ZBTB16 ZFPM2	4.01e-04	13	80	2	25178676
Pubmed	Bromodomain protein Brd4 regulates human immunodeficiency virus transcription through phosphorylation of CDK9 at threonine 29.	PPP2R2A PPP2R2C	4.01e-04	13	80	2	18971272
Pubmed	Functional proteomics mapping of a human signaling pathway.	PAPPA2 THAP2 ZBTB16 KIF3B ZNF76 GPNMB ZZEF1	4.30e-04	591	80	7	15231748
Pubmed	Direct activation of protein phosphatase-2A0 by HIV-1 encoded protein complex NCp7:vpr.	PPP2R2A PPP2R2C	4.67e-04	14	80	2	9013886
Pubmed	Increasing the ratio of PP2A core enzyme to holoenzyme inhibits Tat-stimulated HIV-1 transcription and virus production.	PPP2R2A PPP2R2C	4.67e-04	14	80	2	9400615
Pubmed	Dephosphorylation of CDK9 by protein phosphatase 2A and protein phosphatase-1 in Tat-activated HIV-1 transcription.	PPP2R2A PPP2R2C	4.67e-04	14	80	2	16048649
Pubmed	Mechanism of GTP hydrolysis by G-protein alpha subunits.	ADCY2 ADCY7	5.38e-04	15	80	2	7937899
Pubmed	Prohibitin is required for Ras-induced Raf-MEK-ERK activation and epithelial cell migration.	PPP2R2A PPP2R2C	5.38e-04	15	80	2	16041367
Pubmed	Resolution of cell fate decisions revealed by single-cell gene expression analysis from zygote to blastocyst.	ZNF7 ZNF18 ZNF836 ZNF609 ZNF43 ZNF180 ZNF76 ZNF235	5.45e-04	808	80	8	20412781
Pubmed	Clustered organization of homologous KRAB zinc-finger genes with enhanced expression in human T lymphoid cells.	ZNF43 ZNF112	6.14e-04	16	80	2	8467795
Pubmed	Regulation of HIV-1 transcription by protein phosphatase 1.	PPP2R2A PPP2R2C	6.95e-04	17	80	2	17266553
Pubmed	[Action of protein phosphatase-1 on Tat-dependent HIV-1 transcription and its related inhibitors].	PPP2R2A PPP2R2C	6.95e-04	17	80	2	21351466
Pubmed	Molecular mechanisms involved in HIV-1-Tat mediated inhibition of telomerase activity in human CD4(+) T lymphocytes.	PPP2R2A PPP2R2C	7.81e-04	18	80	2	23287597
Pubmed	Functional dynamics of H3K9 methylation during meiotic prophase progression.	KDM3A ZBTB16	8.71e-04	19	80	2	17599069
Pubmed	Trans-ancestry analysis reveals genetic and nongenetic associations with COVID-19 susceptibility and severity.	NFASC HPSE2	9.66e-04	20	80	2	33888907
Pubmed	A year of COVID-19 GWAS results from the GRASP portal reveals potential genetic risk factors.	NFASC HPSE2	9.66e-04	20	80	2	35224516
Pubmed	Systematic Affinity Purification Coupled to Mass Spectrometry Identified p62 as Part of the Cannabinoid Receptor CB2 Interactome.	SEL1L FANCD2 ZZEF1	9.76e-04	84	80	3	31616248
Pubmed	Clustering of C2-H2 zinc finger motif sequences within telomeric and fragile site regions of human chromosomes.	ZNF22 ZNF71	1.17e-03	22	80	2	1505991
Pubmed	Identification and classification of 16 new kinesin superfamily (KIF) proteins in mouse genome.	KIF3B KIF3C	1.51e-03	25	80	2	9275178
Pubmed	HIV-1 Vpr induces cell cycle G2 arrest in fission yeast (Schizosaccharomyces pombe) through a pathway involving regulatory and catalytic subunits of PP2A and acting on both Wee1 and Cdc25.	PPP2R2A PPP2R2C	1.64e-03	26	80	2	11531413
Pubmed	Genome-Wide Mapping and Interrogation of the Nmp4 Antianabolic Bone Axis.	ZNF384 CHD2	1.64e-03	26	80	2	26244796
Pubmed	Identification, partial characterization, and genetic mapping of kinesin-like protein genes in mouse.	KIF3B KIF3C	1.64e-03	26	80	2	9339368
Pubmed	Prediction of the coding sequences of unidentified human genes. XI. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.	KDM3A NFASC TAB2	1.66e-03	101	80	3	9872452
Pubmed	The STUbL RNF4 regulates protein group SUMOylation by targeting the SUMO conjugation machinery.	SEL1L ZNF771 ZNF384 ZNF22 ZNF609 ZNF184 NFASC TAB2 CHD2	1.77e-03	1203	80	9	29180619
Pubmed	An integrated workflow for charting the human interaction proteome: insights into the PP2A system.	PPP2R2A PPP2R2C PPP2R2D	1.86e-03	105	80	3	19156129
Pubmed	Regulator of sex-limitation (Rsl) encodes a pair of KRAB zinc-finger genes that control sexually dimorphic liver gene expression.	ZNF43 ADCY2	2.04e-03	29	80	2	14563677
Pubmed	Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.	KMT2C PPP2R2A PPP2R2C ZNF609 ZBTB16 ZNF33A TTLL11 NFASC CHD2 ADGRD1	2.17e-03	1489	80	10	28611215
Pubmed	Follow-up association studies of chromosome region 9q and nonsyndromic cleft lip/palate.	TTLL11 GABBR2	2.18e-03	30	80	2	20583170
Pubmed	Mouse screen reveals multiple new genes underlying mouse and human hearing loss.	SEL1L ZNF562 KIF3B GLDC TTLL11 ZNF184 ZSCAN2 ADCY2 ADGRD1	2.19e-03	1242	80	9	30973865
Interaction	SERTAD4 interactions	PPP2R2A PPP2R2C PPP2R2D ZNF235	8.53e-07	19	80	4	int:SERTAD4
Interaction	ZNF836 interactions	ZNF836 ARHGAP24 ZNF562	1.19e-06	6	80	3	int:ZNF836
Interaction	IER5 interactions	PPP2R2A PPP2R2C PPP2R2D	1.67e-05	13	80	3	int:IER5
Interaction	ZNF235 interactions	ARHGAP24 ZNF112 ZNF235	1.67e-05	13	80	3	int:ZNF235
Interaction	ZCCHC8 interactions	FANCD2 PPP2R2A PPP2R2C PPP2R2D GLDC TAF15	3.41e-05	154	80	6	int:ZCCHC8
Interaction	TRIM28 interactions	FANCD2 ZNF7 ZNF22 ZNF573 ARHGAP24 ZNF211 ZNF562 ZNF33A ZNF197 ZNF184 ZIM2 ZNF480 TAF15 ZNF841 ZNF30 ZNF112 ZNF235	5.45e-05	1474	80	17	int:TRIM28
Cytoband	Ensembl 112 genes in cytogenetic band chr19q13	ZNF836 ZNF573 ZNF211 ZNF570 ZNF180 ZIM2 ZNF480 ZNF841 ZNF225 ZNF30 ZNF112 ZNF235 ZNF404 ZNF71	1.80e-08	1192	80	14	chr19q13
Cytoband	19q13.2	ZNF180 ZNF225 ZNF112 ZNF235	2.01e-04	164	80	4	19q13.2
Cytoband	19q13.41	ZNF836 ZNF480 ZNF841	3.53e-04	78	80	3	19q13.41
Cytoband	19q13.4	ZNF211 ZIM2 ZNF71	3.66e-04	79	80	3	19q13.4
GeneFamily	Zinc fingers C2H2-type\|ZF class homeoboxes and pseudogenes	ZNF7 ZNF771 ZNF384 ZNF18 ZNF836 ZNF22 ZNF609 ZNF573 ZBTB16 ZNF211 ZNF562 ZNF33A ZNF43 ZNF570 ZNF180 ZNF197 ZNF184 ZIM2 ZNF480 ZNF76 ZSCAN2 ZNF841 ZNF225 ZNF30 ZNF112 ZNF519 ZNF235 ZNF454 ZBTB42 ZFPM2 ZNF404 ZNF71	2.69e-27	718	67	32	28
GeneFamily	Adenylate cyclases\|Deafness associated genes	ADCY4 ADCY2 ADCY7	5.73e-06	10	67	3	53
GeneFamily	WD repeat domain containing\|Protein phosphatase 2 regulatory subunits	PPP2R2A PPP2R2C PPP2R2D	2.14e-05	15	67	3	696
GeneFamily	Zinc fingers RANBP2-type \|RNA binding motif containing	TAB2 TAF15	2.71e-03	21	67	2	89
Coexpression	HOWLIN_CITED1_TARGETS_2_DN	TRIM34 ZNF519 BID	2.16e-05	18	80	3	M1708
Coexpression	GSE14769_UNSTIM_VS_120MIN_LPS_BMDM_UP	ZNF771 OGFRL1 TOR4A TUBGCP4 ZBTB42 BID	3.35e-05	199	80	6	M3503
Coexpression	GSE4748_CTRL_VS_CYANOBACTERIUM_LPSLIKE_STIM_DC_3H_UP	KMT2C ZBTB16 CHD2 TAF15 TUBGCP4 FBXL3	3.44e-05	200	80	6	M6477
Coexpression	GSE7852_LN_VS_FAT_TCONV_UP	THAP2 ZNF43 TRIM34 ATP13A3 ZNF841 TUBGCP4	3.44e-05	200	80	6	M5747
ToppCell	severe-unassigned\|severe / disease stage, cell group and cell class	ZNF18 ZNF573 KIF3C ZNF841 TUBGCP4	1.20e-05	165	80	5	f9ddd547992fec065d539a1d0305acba8fc7d79c
ToppCell	390C-Lymphocytic-CD4_T-cell-Treg_cell_1\|CD4_T-cell / Donor, Lineage, Cell class and subclass (all cells)	ZNF7 ZNF211 ZNF562 ZBTB42 ZNF71	2.25e-05	188	80	5	2c4e791df69a9df29922f9117e5cac7787c129ce
ToppCell	390C-Lymphocytic-CD4_T-cell-Treg_cell_1\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	ZNF7 ZNF211 ZNF562 ZBTB42 ZNF71	2.25e-05	188	80	5	b1ec7c45aedcc3d22cac898c6a3679e7f8b44c77
ToppCell	facs-Lung-nan-3m-Mesenchymal-pulmonary_interstitial_fibroblast\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PAPPA2 PDE1A HPSE2 ADCY2 ZFPM2	2.37e-05	190	80	5	c7bd087f36321cec61b98657433b4d19d135791f
ToppCell	PCW_13-14\|World / Celltypes from embryonic and fetal-stage human lung	ARHGAP24 ZBTB16 STXBP6 HPSE2 CNKSR2	2.37e-05	190	80	5	62a3ec1ae0829602b0569cc051210551644f1d46
ToppCell	facs-Lung-nan-3m-Mesenchymal-Myofibroblast\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PAPPA2 PDE1A HPSE2 ADCY2 ZFPM2	2.37e-05	190	80	5	834218fcc59df5e7e52de154272f3d55d81d0dac
ToppCell	facs-Lung-3m-Mesenchymal-myofibroblast\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	PAPPA2 PDE1A CALHM5 HPSE2 ADCY2	2.43e-05	191	80	5	fd8331c7abdd999f55ba43d307945c6abfccbf84
ToppCell	PCW_13-14-Mesenchymal-Mesenchymal_fibroblastic-mes_immature_COL13A1^pos_fibro1_(4)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	ZBTB16 HPSE2 CNKSR2 ADCY2 ZFPM2	2.55e-05	193	80	5	9f69edc97b868d23998abc98928a2e89a885ef8a
ToppCell	facs-Lung-3m-Mesenchymal-myofibroblast-myofibroblast_cell\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	PAPPA2 PDE1A CALHM5 HPSE2 ADCY2	2.68e-05	195	80	5	c6bb16c0076639c6ddef1a15d8cba44bc29c077d
ToppCell	facs-Lung-3m-Mesenchymal-myofibroblast-myofibroblast_cell-pulmonary_interstitial_myofibroblast\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	PAPPA2 PDE1A CALHM5 HPSE2 ADCY2	2.68e-05	195	80	5	ea89f80d3d7e9f737442f7c1aa1791d277ffc90c
ToppCell	Tracheal-NucSeq-Stromal-Peri/Epineurial_-NAF_epineurial\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	PDE1A STXBP6 CNKSR2 ADGRD1 ZFPM2	2.96e-05	199	80	5	9c2db0bb94cba71a3cc1827844da090e213e0258
ToppCell	Tracheal-NucSeq-Stromal-Schwann-Schwann_Myelinating\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	CELSR2 GLDC ZIM2 NFASC GABBR2	2.96e-05	199	80	5	4e4bdcd2e8b518156d5ebd294804180acaa3566b
Drug	vinylene	ZNF18 ZNF22 ZBTB16 ZNF33A ZNF180 ZNF197 ZIM2 ZNF480 ZNF235 ZFPM2 ZNF71	9.75e-10	245	80	11	CID000006326
Drug	2',5'-dd3'-FSBA	ADCY4 ADCY2 ADCY7	4.92e-06	10	80	3	CID003081206
Drug	NC-5Z	ADCY4 ADCY2 ADCY7	4.92e-06	10	80	3	CID003035914
Drug	Paroxetine maleate [64006-44-6]; Down 200; 1uM; PC3; HT_HG-U133A	PAPPA2 ZNF609 ZNF573 STXBP6 ZSCAN2 GPNMB ADCY2	5.69e-06	195	80	7	3821_DN
Drug	Cephalexin monohydrate [23325-78-2]; Down 200; 11uM; PC3; HT_HG-U133A	ZNF609 ZNF197 ZNF76 ZSCAN2 ATP13A3 ZNF235 GABBR2	6.28e-06	198	80	7	4654_DN
Drug	AC1NY9KD	ADCY4 ADCY2 ADCY7	6.75e-06	11	80	3	CID005771741
Drug	AC1L40QM	ADCY4 ADCY2 ADCY7	6.75e-06	11	80	3	CID000099213
Drug	B-Mlvp	ADCY4 ADCY2 ADCY7	6.75e-06	11	80	3	CID000195648
Drug	FCE 23884	ADCY4 ADCY2 ADCY7	1.16e-05	13	80	3	CID000065898
Drug	BMY 42393	ADCY4 ADCY2 ADCY7	1.84e-05	15	80	3	CID000131961
Drug	Ro 41-9067	ADCY4 ADCY2 ADCY7	3.89e-05	19	80	3	CID000125800
Drug	SK&F 82958	ADCY4 ADCY2 ADCY7	3.89e-05	19	80	3	ctd:C071262
Drug	NSC-4928	PAPPA2 ADCY4 ADCY2 ADCY7	5.19e-05	58	80	4	CID000221086
Drug	reproterol	ADCY4 ADCY2 ADCY7	5.31e-05	21	80	3	CID000025654
Drug	GSK835726	ADCY4 ADCY2 ADCY7	6.13e-05	22	80	3	CID005311268
Drug	8-phenyltheophylline	ADCY4 P2RY13 ADCY2 ADCY7	6.75e-05	62	80	4	CID000001922
Drug	beta-CNA	ADCY4 ADCY2 ADCY7	7.03e-05	23	80	3	CID005486190
Drug	Scpb	ADCY4 ADCY2 ADCY7	7.03e-05	23	80	3	CID000123843
Drug	Amikacin hydrate [37517-28-5]; Down 200; 6.6uM; MCF7; HT_HG-U133A	ZNF7 KDM3A ZNF384 ZNF211 TAB2 ATP13A3	7.06e-05	198	80	6	5314_DN
Drug	NAIN	ADCY4 ADCY2 ADCY7	8.02e-05	24	80	3	CID000195228
Drug	TL-99	ADCY4 ADCY2 ADCY7	8.02e-05	24	80	3	CID000122132
Drug	trimetoquinol	ADCY4 ADCY2 ADCY7	8.02e-05	24	80	3	CID000005581
Drug	AC1L8VEV	ADCY4 ADCY2 ADCY7	8.02e-05	24	80	3	CID000433433
Drug	PD 81,723	ADCY4 ADCY2 ADCY7	9.09e-05	25	80	3	CID000122028
Drug	octimibate	ADCY4 ADCY2 ADCY7	9.09e-05	25	80	3	CID000065676
Drug	metaproterenol	ADCY4 ADCY2 ADCY7	1.02e-04	26	80	3	CID000004086
Drug	SM-10906	ADCY4 ADCY2 ADCY7	1.15e-04	27	80	3	CID006442261
Drug	3'-AMP	ADCY4 P2RY13 ADCY2 ADCY7	1.21e-04	72	80	4	CID000041211
Drug	ethacrynic acid	ADCY4 KIF3B KIF3C ADCY2 ADCY7	1.27e-04	138	80	5	CID000003278
Drug	tetrahydrofurfuryl alcohol	ADCY4 ADCY2 ADCY7	1.28e-04	28	80	3	CID000007360
Drug	prenalterol	ADCY4 ADCY2 ADCY7	1.28e-04	28	80	3	CID000042396
Drug	desacetylnantradol	ADCY4 ADCY2 ADCY7	1.28e-04	28	80	3	CID000125211
Drug	Nocloprostum	ADCY4 ADCY2 ADCY7	1.28e-04	28	80	3	CID006435380
Drug	tolazoline	ADCY4 ADCY2 ADCY7	1.43e-04	29	80	3	CID000005504
Drug	etazolate	ADCY4 GABBR2 ADCY7	1.43e-04	29	80	3	CID000003277
Drug	AC1N2DGT	ADCY4 ADCY2 ADCY7	1.58e-04	30	80	3	CID004045015
Drug	Peptavlon	ADCY4 ZNF22 ADCY2 ADCY7	1.65e-04	78	80	4	CID000021701
Drug	Tyr-D-Ala-Gly-N-methyl-Phe-Gly-ol	ADCY4 GABBR2 ADCY2 ADCY7	1.82e-04	80	80	4	CID004488326
Drug	sumatriptan	ADCY4 P2RY13 ADCY2 ADCY7	1.82e-04	80	80	4	CID000005358
Drug	dopexamine	ADCY4 ADCY2 ADCY7	1.93e-04	32	80	3	CID000055483
Drug	DPDPE	ADCY4 GABBR2 ADCY2 ADCY7	2.01e-04	82	80	4	CID000104787
Drug	6,7-ADTN	ADCY4 ADCY2 ADCY7	2.11e-04	33	80	3	CID000003153
Drug	phosphonate analog	ADCY4 ADCY2 ADCY7	2.11e-04	33	80	3	CID000475766
Disease	autosomal dominant cerebellar ataxia (implicated_via_orthology)	PPP2R2A PPP2R2C PPP2R2D	3.55e-06	12	76	3	DOID:1441 (implicated_via_orthology)
Disease	central nervous system cancer	PAPPA2 ZBTB16 HPSE2	7.01e-05	31	76	3	EFO_0000326
Disease	Pathological accumulation of air in tissues	PPP2R2A PPP2R2C	4.25e-04	12	76	2	C0013990
Disease	cystatin-F measurement	KIF3B ZFPM2	7.67e-04	16	76	2	EFO_0008104
Disease	amyotrophic lateral sclerosis (implicated_via_orthology)	TAF15 ATP13A3	2.72e-03	30	76	2	DOID:332 (implicated_via_orthology)
Disease	Epileptic encephalopathy	CHD2 GABBR2	2.72e-03	30	76	2	C0543888

Protein segments in the cluster

Peptide	Gene	Start	Entry
RIFANGHTYHINSIS	PPP2R2C	166	Q9Y2T4
IFANAHTYHINSISI	PPP2R2A	171	P63151
TIRNQRYHIHANLSF	ADGRD1	596	Q6QNK2
QTESQQIRYFTHHSV	ATP13A3	131	Q9H7F0
NHTVNHTYVLNGTFS	GPNMB	296	Q14956
RIFANAHTYHINSIS	PPP2R2D	176	Q66LE6
ESTNNFHSLYVKRHQ	ADCY4	256	Q8NFM4
NTHRPVFQSSHYTVN	CELSR2	706	Q9HCU4
NFHSLYVKRHQNVSI	ADCY7	266	P51828
NSAITYRITNHSHFR	CDHR5	396	Q9HBB8
QQSYHSQRENYSHHT	TAF15	146	Q92804
TTFFHHINLQYSTIS	MOB2	61	Q70IA6
FQHLNESQHNYLRIT	OGFRL1	226	Q5TC84
AFHQYSNNISTLDVH	KMT2C	4276	Q8NEZ4
SVINFHQHLFSHLTQ	ZFPM2	346	Q8WW38
HIFTHISRSQNQQYL	KIF3C	126	O14782
YEHTGTTNNFHIQTR	PDE1A	261	P54750
HLSISHVNYFLDQFQ	TUBGCP4	116	Q9UGJ1
NHHNHNYVRGSITLF	HPSE2	486	Q8WWQ2
FHFARVPYTHSQTNN	P2RY13	271	Q9BPV8
INHRHYTVNLNTYTA	PARP14	1571	Q460N5
YSCNARFHFTHTIQQ	NFASC	211	O94856
QNVLFHHTTSVLLNF	PAPPA2	1331	Q9BXP8
HNRLSTYDNVHQQFS	ARHGAP24	526	Q8N264
NNFHNLYVKRHTNVS	ADCY2	276	Q08462
LTQEFRYLSQTHTNH	KDM3A	1276	Q9Y4C1
HYTFQQPRHQSSVKL	CCDC126	31	Q96EE4
QAYRHILFNTQINIH	ARV1	86	Q9H2C2
TIQTISFLSYLFHQH	CHD2	516	O14647
QIIKRHSNHLQYVSF	FBXL3	101	Q9UKT7
FHQSQQHYSTLHRVV	CALHM5	271	Q8N5C1
FHTTVNFINQNLRTY	BID	171	P55957
LHASSRHQRIQDFNY	GABBR2	376	O75899
LSQSVHYLQNFHQSI	FANCD2	1111	Q9BXW9
ISYSFEHLQANQHLA	TRIM34	61	Q9BYJ4
TFSTHSLGNQHIYQR	TRIM42	521	Q8IWZ5
TDHTVTFLQYQVFSH	TSEN54	146	Q7Z6J9
TSLNLDLQSQNIYHH	TAB2	76	Q9NYJ8
FIHYRLASEQQHSAQ	SEL1L	651	Q9UBV2
NIIHLNLSYNHFTDL	OMG	56	P23515
NLSYNHFTDLHNQLT	OMG	61	P23515
HFTDLHNQLTQYTNL	OMG	66	P23515
HQFSHFNVLTHQTFL	TASOR	1606	Q9UK61
ETTLYHTFQQSSLQH	CNKSR2	531	Q8WXI2
FSSGSYLVQHQRIHT	ZNF30	521	P17039
SFRNSSSFNVHIQIH	ZNF562	296	Q6V9R5
HLTNYSLNIHSGNFI	TTLL11	431	Q8NHH1
TFFQILHHTCQRYLT	STXBP6	121	Q8NFX7
FANTSYLAQHLRIHS	ZNF384	326	Q8TF68
FTQSAYLFDHQRLHN	ZNF197	631	O14709
FSYNSNLIRHQRIHT	ZSCAN2	371	Q7Z7L9
FAQSSNYAQHLRVHT	ZNF771	156	Q7L3S4
FRSGYQLTLHQRFHT	ZNF573	171	Q86YE8
TFTLYRNLTRHQNIH	ZNF573	366	Q86YE8
FTLYRNLTRHQNIHT	ZNF573	451	Q86YE8
ILFHRNSQHYTLDFL	ZBTB16	61	Q05516
AFNRGSYLTQHQRIH	ZNF519	356	Q8TB69
IFTHISRSQNQQYLV	KIF3B	126	O15066
HTHLLSTNTAYRQQY	ZNF609	991	O15014
SFSQIYSLNSHRKVH	ZNF211	321	Q13398
FNQYSNLTTHNKIHT	ZNF43	771	P17038
FRFYSQLIQHQIIHT	ZNF404	196	Q494X3
AFYQKSQLTQHQRIH	ZNF33A	616	Q06730
SRNSYLIQHYRTHTQ	ZIM2	476	Q9NZV7
FTQNSQLYSHRRVHT	ZNF225	521	Q9UK10
FQYSHNLSRHTVVHT	ZBTB42	371	B2RXF5
VFYQNSQLVRHQIIH	ZNF841	321	Q6ZN19
SFSQSYKLVAHQRTH	ZNF180	501	Q9UJW8
FSNNSYLARHQRIHA	ZNF480	296	Q8WV37
QRSHHFHNAIYVLLS	TOR4A	286	Q9NXH8
SFSQRSYLQSHQSVH	ZNF112	701	Q9UJU3
FSQFAYLAQHQRVHT	ZNF570	311	Q96NI8
SFFQSSNLIQHRRIH	ZNF22	91	P17026
QYSQHFAFIASHLLQ	ZZEF1	2321	O43149
AFNQSTSFLQHQRIH	ZNF454	336	Q8N9F8
TFYRNSQLIFHQRTH	ZNF18	416	P17022
ATTYNKHINISFHRF	THAP2	11	Q9H0W7
SQSSYLIQHQRFHIG	ZNF71	336	Q9NQZ8
QSSYFQAHQRVHTGE	ZNF235	526	Q14590
FTSATNYKNHVRIHT	ZNF76	296	P36508
FSQSYNLAIHQRIHT	ZNF836	311	Q6ZNA1
FSYLSNLNQHQKTHT	ZNF184	511	Q99676
TFSQSTYLIQHQRIH	ZNF184	706	Q99676
AFSQNSTLFQHQIIH	ZNF7	561	P17097
THQVFNSYHSETNIV	GLDC	521	P23378