Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	dynein light intermediate chain binding	DNHD1 CCDC88A DNAH12 DNAH17 DNAH11	3.64e-06	28	171	5	GO:0051959
GeneOntologyMolecularFunction	ribose phosphate diphosphokinase activity	PRPS2 PRPS1L1 PRPS1	6.09e-06	5	171	3	GO:0004749
GeneOntologyMolecularFunction	diphosphotransferase activity	PRPS2 PRPS1L1 PRPS1	1.21e-05	6	171	3	GO:0016778
GeneOntologyMolecularFunction	minus-end-directed microtubule motor activity	DNHD1 DNAH12 DNAH17 DNAH11	1.45e-05	18	171	4	GO:0008569
GeneOntologyMolecularFunction	structural constituent of postsynaptic actin cytoskeleton	POTEF POTEE POTEI	9.68e-05	11	171	3	GO:0098973
GeneOntologyMolecularFunction	dynein intermediate chain binding	DNHD1 DNAH12 DNAH17 DNAH11	2.75e-04	37	171	4	GO:0045505
GeneOntologyMolecularFunction	transferase activity, transferring phosphorus-containing groups	PRPS2 CTU2 HK3 GLYCTK OBSCN MAP3K1 NMNAT3 PRPS1L1 BLK PHKG2 NRBP2 SPHK1 SHPK NEK8 CDIPT MAPK4 EIF2AK1 ULK2 PRPS1	4.45e-04	938	171	19	GO:0016772
GeneOntologyMolecularFunction	cytoskeletal motor activity	DNHD1 MYO9A MYO9B DNAH12 DNAH17 DNAH11	5.40e-04	118	171	6	GO:0003774
GeneOntologyMolecularFunction	ADP binding	PRPS2 MYO9B MAT1A PRPS1	7.53e-04	48	171	4	GO:0043531
GeneOntologyMolecularFunction	ATP-dependent activity	DNHD1 ERCC6 ATP7B MYO9A MYO9B DDX11 DNAH12 DNAH17 MCM9 SHOC1 NAV1 ATP11C SNRNP200 DNAH11	8.45e-04	614	171	14	GO:0140657
GeneOntologyMolecularFunction	kinase activity	PRPS2 HK3 GLYCTK OBSCN MAP3K1 PRPS1L1 BLK PHKG2 NRBP2 SPHK1 SHPK NEK8 MAPK4 EIF2AK1 ULK2 PRPS1	8.99e-04	764	171	16	GO:0016301
GeneOntologyBiologicalProcess	5-phosphoribose 1-diphosphate metabolic process	PRPS2 PRPS1L1 PRPS1	1.10e-05	6	171	3	GO:0046391
GeneOntologyBiologicalProcess	5-phosphoribose 1-diphosphate biosynthetic process	PRPS2 PRPS1L1 PRPS1	1.10e-05	6	171	3	GO:0006015
GeneOntologyCellularComponent	ribose phosphate diphosphokinase complex	PRPS2 PRPS1L1 PRPS1	5.41e-06	5	172	3	GO:0002189
GeneOntologyCellularComponent	centriole	RTTN FTCD CEP350 CCDC88A SCLT1 ODAD3 PCM1 PCNT	9.15e-05	172	172	8	GO:0005814
GeneOntologyCellularComponent	laminin-3 complex	LAMA1 LAMA3	2.01e-04	3	172	2	GO:0005608
GeneOntologyCellularComponent	protein acetyltransferase complex	POTEF KANSL3 POTEE NAA25 POTEI BRD1	2.22e-04	104	172	6	GO:0031248
GeneOntologyCellularComponent	acetyltransferase complex	POTEF KANSL3 POTEE NAA25 POTEI BRD1	2.86e-04	109	172	6	GO:1902493
GeneOntologyCellularComponent	FAR/SIN/STRIPAK complex	SIKE1 CTTNBP2NL STRIP1	3.42e-04	17	172	3	GO:0090443
GeneOntologyCellularComponent	striated muscle myosin thick filament	OBSCN TRIM32	4.00e-04	4	172	2	GO:0005863
GeneOntologyCellularComponent	H4 histone acetyltransferase complex	POTEF KANSL3 POTEE POTEI	5.07e-04	45	172	4	GO:1902562
GeneOntologyCellularComponent	supramolecular fiber	DLGAP2 MYO9A MYO9B POTEF SPTAN1 SARM1 OBSCN TOGARAM2 RIBC1 DAG1 MAP3K1 POTEE FXR1 DNAH12 TRIM32 DNAH17 NAV1 POTEI CAMSAP2 PCNT DNAH11	7.10e-04	1179	172	21	GO:0099512
GeneOntologyCellularComponent	supramolecular polymer	DLGAP2 MYO9A MYO9B POTEF SPTAN1 SARM1 OBSCN TOGARAM2 RIBC1 DAG1 MAP3K1 POTEE FXR1 DNAH12 TRIM32 DNAH17 NAV1 POTEI CAMSAP2 PCNT DNAH11	7.73e-04	1187	172	21	GO:0099081
GeneOntologyCellularComponent	dynein complex	DNHD1 DNAH12 DNAH17 DNAH11	1.02e-03	54	172	4	GO:0030286
GeneOntologyCellularComponent	histone acetyltransferase complex	POTEF KANSL3 POTEE POTEI BRD1	1.08e-03	94	172	5	GO:0000123
GeneOntologyCellularComponent	axonemal dynein complex	DNHD1 DNAH12 DNAH17	1.10e-03	25	172	3	GO:0005858
GeneOntologyCellularComponent	ciliary basal body	RTTN CCDC178 CCDC88A CAMSAP2 ODAD3 PCM1 PCNT	1.18e-03	195	172	7	GO:0036064
GeneOntologyCellularComponent	cilium	DNHD1 RTTN TOGARAM2 RIBC1 CCDC178 LRRC43 CCDC88A DNAH12 NEK8 DNAH17 DLEC1 SCLT1 CAMSAP2 ODAD3 PCM1 PCNT DNAH11	1.22e-03	898	172	17	GO:0005929
GeneOntologyCellularComponent	actin filament	MYO9A MYO9B POTEF MAP3K1 POTEE POTEI	1.33e-03	146	172	6	GO:0005884
GeneOntologyCellularComponent	axoneme	DNHD1 RIBC1 LRRC43 DNAH12 DNAH17 ODAD3 DNAH11	1.66e-03	207	172	7	GO:0005930
GeneOntologyCellularComponent	ciliary plasm	DNHD1 RIBC1 LRRC43 DNAH12 DNAH17 ODAD3 DNAH11	1.71e-03	208	172	7	GO:0097014
GeneOntologyCellularComponent	B-WICH complex	ERCC6 SF3B1	1.82e-03	8	172	2	GO:0110016
GeneOntologyCellularComponent	NuA4 histone acetyltransferase complex	POTEF POTEE POTEI	2.28e-03	32	172	3	GO:0035267
GeneOntologyCellularComponent	H4/H2A histone acetyltransferase complex	POTEF POTEE POTEI	2.28e-03	32	172	3	GO:0043189
HumanPheno	Ventriculomegaly	FLII USP18 CTU2 ERCC6 UBE4B LRRC32 RTTN LAMA1 DAG1 MPDZ OCA2 GABBR2 ANKLE2 FANCB CCDC88A SHPK NEK8 PGAP1 NUP188 RERE EXOC2 ODAD3 D2HGDH PCNT DNAH11	7.23e-06	790	66	25	HP:0002119
Domain	PRPP_SYNTHASE	PRPS2 PRPS1L1 PRPS1	6.77e-07	3	165	3	PS00114
Domain	PRib_PP_synth_CS	PRPS2 PRPS1L1 PRPS1	6.77e-07	3	165	3	IPR000842
Domain	Pribosyltran_N	PRPS2 PRPS1L1 PRPS1	6.68e-06	5	165	3	PF13793
Domain	Pribosyl_synth	PRPS2 PRPS1L1 PRPS1	6.68e-06	5	165	3	PF14572
Domain	Rib-P_diPkinase	PRPS2 PRPS1L1 PRPS1	6.68e-06	5	165	3	IPR005946
Domain	Pribosyltran_N	PRPS2 PRPS1L1 PRPS1	6.68e-06	5	165	3	IPR029099
Domain	ARM-type_fold	NOC2L RTTN SARM1 TOGARAM2 NBEA TRIP12 MAP3K1 FOCAD SF3B1 MROH6 EIF4G1 NUP188	4.97e-05	339	165	12	IPR016024
Domain	Pribosyltran	PRPS2 PRPS1L1 PRPS1	1.06e-04	11	165	3	PF00156
Domain	PRTase-like	PRPS2 PRPS1L1 PRPS1	1.40e-04	12	165	3	IPR029057
Domain	PRibTrfase_dom	PRPS2 PRPS1L1 PRPS1	1.40e-04	12	165	3	IPR000836
Domain	-	PRPS2 PRPS1L1 PRPS1	1.40e-04	12	165	3	3.40.50.2020
Domain	Dynein_heavy_dom-2	DNHD1 DNAH12 DNAH11	2.29e-04	14	165	3	IPR013602
Domain	DHC_N2	DNHD1 DNAH12 DNAH11	2.29e-04	14	165	3	PF08393
Domain	DHC_fam	DNHD1 DNAH12 DNAH11	2.85e-04	15	165	3	IPR026983
Domain	Dynein_heavy	DNHD1 DNAH12 DNAH11	2.85e-04	15	165	3	PF03028
Domain	Dynein_heavy_dom	DNHD1 DNAH12 DNAH11	2.85e-04	15	165	3	IPR004273
Domain	Actin_CS	POTEF POTEE POTEI	3.48e-04	16	165	3	IPR004001
Domain	ACTINS_2	POTEF POTEE POTEI	4.20e-04	17	165	3	PS00432
Domain	Actin/actin-like_CS	POTEF POTEE POTEI	5.01e-04	18	165	3	IPR020902
Domain	ACTINS_ACT_LIKE	POTEF POTEE POTEI	5.91e-04	19	165	3	PS01132
Domain	Laminin_domII	LAMA1 LAMA3	7.62e-04	5	165	2	IPR010307
Domain	Laminin_aI	LAMA1 LAMA3	7.62e-04	5	165	2	IPR009254
Domain	Laminin_I	LAMA1 LAMA3	7.62e-04	5	165	2	PF06008
Domain	Laminin_II	LAMA1 LAMA3	7.62e-04	5	165	2	PF06009
Pathway	REACTOME_PENTOSE_PHOSPHATE_PATHWAY	PRPS2 PRPS1L1 SHPK PRPS1	6.34e-06	15	120	4	M27682
Pathway	REACTOME_PENTOSE_PHOSPHATE_PATHWAY	PRPS2 PRPS1L1 SHPK PRPS1	6.34e-06	15	120	4	MM15404
Pathway	KEGG_PENTOSE_PHOSPHATE_PATHWAY	PRPS2 TKTL1 PRPS1L1 PRPS1	7.53e-05	27	120	4	M1386
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	MTA2 PITPNM2 FLII MAN2A2 UBE4B MYO9B RTTN OBSCN ZZEF1 FOCAD KANSL3 MYOF SLC2A4RG MROH6 SPHK1 NEK8 EIF4G1 NAV1 CACNA1H NUP188 ULK2 TTC38 D2HGDH PCNT	1.70e-09	1105	174	24	35748872
Pubmed	In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.	PRPS2 EFCAB5 FAM184B COPA NOC2L POTEF SPTAN1 COX6C TKTL1 LRRC43 ANKLE2 TRIP12 PRPS1L1 DDX11 POTEE FXR1 SF3B1 EIF4G1 ATP11C DLEC1 POTEI CAMSAP2 POFUT2 DOP1A AMIGO2 PCNT PRPS1	3.61e-09	1442	174	27	35575683
Pubmed	Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.	CA11 FLII COPA UBE4B SPTAN1 NBEA NCAPH2 FTCD CPNE5 TRIP12 CCDC85A CEP350 FOCAD NAA25 GDAP1L1 SF3B1 APPL2 TRIM32 HECTD2 EIF4G1 CCDC15 EIF2AK1 SNRNP200 PCM1 PCNT	6.88e-09	1285	174	25	35914814
Pubmed	Promoter regions of the human X-linked housekeeping genes PRPS1 and PRPS2 encoding phosphoribosylpyrophosphate synthetase subunit I and II isoforms.	PRPS2 PRPS1L1 PRPS1	1.23e-07	3	174	3	1314091
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	MYO9A POTEF SPTAN1 MPDZ TRIP12 MEX3C NEDD4 CEP350 VPS13D FXR1 CCDC88A EIF4G1 NAV1 MAPK4 BRD1 CAMSAP2 PCM1 DOP1A	3.71e-07	861	174	18	36931259
Pubmed	Large-scale characterization of HeLa cell nuclear phosphoproteins.	FLII COPA UBE4B KDM5C SPTAN1 TRIP12 CTTNBP2NL STRIP1 KANSL3 MYOF SF3B1 SLC4A1AP EIF4G1 RERE EXOC2 SNRNP200 PCM1	4.04e-07	774	174	17	15302935
Pubmed	Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.	GTPBP4 FLII DLGAP2 SPTAN1 MPDZ NBEA GABBR2 TRIM3 STRIP1 NEDD4 FXR1 CCDC88A SF3B1 TAX1BP1 EIF4G1 NAV1 CAMSAP2 PCM1 PCNT	4.15e-07	963	174	19	28671696
Pubmed	CASPR2 forms a complex with GPR37 via MUPP1 but not with GPR37(R558Q), an autism spectrum disorder-related mutation.	MPDZ GABBR2 CNTNAP2	4.91e-07	4	174	3	25977097
Pubmed	Dystroglycan protein distribution coincides with basement membranes and muscle differentiation during mouse embryogenesis.	LAMA1 LAMA3 DAG1	4.91e-07	4	174	3	17676646
Pubmed	The RNA binding protein MEX3A promotes tumor progression of breast cancer by post-transcriptional regulation of IGFBP4.	COPA MYO9B KDM5C SPTAN1 ANKLE2 MYOF AMOTL1 EIF4G1 SHOC1 NAV1 PCM1	1.03e-06	332	174	11	37433992
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	UBE4B RAPGEF5 STRIP1 NEDD4 FOCAD ZFR2 NAV1 CACNA1H RERE CAMSAP2 ULK2 PCNT	1.12e-06	407	174	12	12693553
Pubmed	ZZW-115-dependent inhibition of NUPR1 nuclear translocation sensitizes cancer cells to genotoxic agents.	PRPS2 GTPBP4 FLII COPA NOC2L SPTAN1 TRIP12 POTEE MYOF FXR1 SF3B1 EIF4G1 NUP188 SNRNP200 PCM1	1.32e-06	660	174	15	32780723
Pubmed	The deubiquitinase TRABID stabilizes the K29/K48-specific E3 ubiquitin ligase HECTD1.	SIKE1 MPDZ NCAPH2 ZZEF1 TRIP12 CTTNBP2NL STRIP1 ANKRD13A PCNT	1.34e-06	212	174	9	33853758
Pubmed	KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.	MTA2 PITPNM2 FLII DLGAP2 COPA MYO9A SPTAN1 COX6C NBEA TRIM3 STRIP1 FXR1 SF3B1 APPL2 CDIPT EIF4G1 NAV1 CAMSAP2 SNRNP200 PCM1 DNAH11 PRPS1	3.08e-06	1431	174	22	37142655
Pubmed	USP45 and Spindly are part of the same complex implicated in cell migration.	COPA SPTAN1 CPNE5 POTEE VPS13D SF3B1 EIF4G1 SNRNP200 PCM1	3.13e-06	235	174	9	30258100
Pubmed	Cloning and expression analyses of mouse dystroglycan gene: specific expression in maternal decidua at the peri-implantation stage.	LAMA1 LAMA3 DAG1	6.77e-06	8	174	3	8872465
Pubmed	Proteomic analysis and identification of cellular interactors of the giant ubiquitin ligase HERC2.	FLII COPA MYO9B PHKG2 TRMT2A EIF4G1 PCM1	6.81e-06	139	174	7	25476789
Pubmed	Proteomic analyses reveal distinct chromatin-associated and soluble transcription factor complexes.	TCF12 HK3 COPA MYO9B NOC2L KDM5C TRIP12 TRIM3 KANSL3 PHKG2 FXR1 SF3B1 TRMT2A EIF4G1 CCDC15 SNRNP200	7.15e-06	857	174	16	25609649
Pubmed	Histone methyltransferase DOT1L coordinates AR and MYC stability in prostate cancer.	FLII FXR1 SF3B1 TRIM32 TAX1BP1 FAM83D NUP188 SNRNP200 PCM1	8.02e-06	264	174	9	32814769
Pubmed	LRRC31 inhibits DNA repair and sensitizes breast cancer brain metastasis to radiation therapy.	FLII COPA MYO9B TRIP12 MYOF EIF4G1 CNTNAP2 SNRNP200	8.76e-06	202	174	8	33005030
Pubmed	A probability-based approach for high-throughput protein phosphorylation analysis and site localization.	FLII TBRG4 ERCC6 COPA KDM5C ANKLE2 TRIP12 CTTNBP2NL STRIP1 SF3B1 EIF4G1 PCM1	9.67e-06	503	174	12	16964243
Pubmed	Interactomes of Glycogen Synthase Kinase-3 Isoforms.	MYO9A MPDZ CTTNBP2NL CEP350 VPS13D CCDC88A CAMSAP2 PCM1	1.12e-05	209	174	8	36779422
Pubmed	The USP10-HDAC6 axis confers cisplatin resistance in non-small cell lung cancer lacking wild-type p53.	SPTAN1 FXR1 SF3B1 EIF4G1 SNRNP200	1.19e-05	59	174	5	32382008
Pubmed	An integrated workflow for charting the human interaction proteome: insights into the PP2A system.	SIKE1 MYO9A ANKLE2 CTTNBP2NL STRIP1 CEP350	1.54e-05	105	174	6	19156129
Pubmed	Angiomotin-Like 1 Links Paramyxovirus M Proteins to NEDD4 Family Ubiquitin Ligases.	NEDD4 AMOTL1	2.49e-05	2	174	2	30708959
Pubmed	[Increased activity of PRPP synthetase].	PRPS2 PRPS1	2.49e-05	2	174	2	18409517
Pubmed	Kendrin/pericentrin-B, a centrosome protein with homology to pericentrin that complexes with PCM-1.	PCM1 PCNT	2.49e-05	2	174	2	11171385
Pubmed	Class IX Myosins: Motorized RhoGAP Signaling Molecules.	MYO9A MYO9B	2.49e-05	2	174	2	32451867
Pubmed	Sphingosine kinase 1 is upregulated with lysophosphatidic acid receptor 2 in human colorectal cancer.	SPHK1 LPAR2	2.49e-05	2	174	2	26937138
Pubmed	A primate-specific POTE-actin fusion protein plays a role in apoptosis.	POTEF POTEE	2.49e-05	2	174	2	19669888
Pubmed	Binding of laminin alpha1-chain LG4-5 domain to alpha-dystroglycan causes tyrosine phosphorylation of syntrophin to initiate Rac1 signaling.	LAMA1 DAG1	2.49e-05	2	174	2	16475793
Pubmed	TRIM32-TAX1BP1-dependent selective autophagic degradation of TRIF negatively regulates TLR3/4-mediated innate immune responses.	TRIM32 TAX1BP1	2.49e-05	2	174	2	28898289
Pubmed	PRPS1-mediated purine biosynthesis is critical for pluripotent stem cell survival and stemness.	PRPS2 PRPS1	2.49e-05	2	174	2	33493137
Pubmed	Dystroglycan binding to laminin alpha1LG4 module influences epithelial morphogenesis of salivary gland and lung in vitro.	LAMA1 DAG1	2.49e-05	2	174	2	11798066
Pubmed	Tissue-differential expression of two distinct genes for phosphoribosyl pyrophosphate synthetase and existence of the testis-specific transcript.	PRPS2 PRPS1	2.49e-05	2	174	2	2537655
Pubmed	Targeting the EIF2AK1 Signaling Pathway Rescues Red Blood Cell Production in SF3B1-Mutant Myelodysplastic Syndromes With Ringed Sideroblasts.	SF3B1 EIF2AK1	2.49e-05	2	174	2	35926182
Pubmed	Human amnion contains a novel laminin variant, laminin 7, which like laminin 6, covalently associates with laminin 5 to promote stable epithelial-stromal attachment.	LAMA1 LAMA3	2.49e-05	2	174	2	8601594
Pubmed	USP7 targets XIAP for cancer progression: Establishment of a p53-independent therapeutic avenue for glioma.	DNHD1 EFCAB5 GTPBP4 LAMA1 TRIP12 FXR1 SF3B1 SNRNP200	2.53e-05	234	174	8	36243803
Pubmed	Molecular dissection of laminin alpha 5 in vivo reveals separable domain-specific roles in embryonic development and kidney function.	LAMA1 LAMA3 NPHS2	2.62e-05	12	174	3	16750824
Pubmed	Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.	MTA2 GTPBP4 COPA NOC2L SPTAN1 TRIP12 FXR1 SF3B1 EIF4G1 NUP188 SNRNP200 PCM1 PCNT	2.76e-05	653	174	13	22586326
Pubmed	The E3 ubiquitin ligase HECTD1 contributes to cell proliferation through an effect on mitosis.	MTA2 GTPBP4 EXOC6 FLII ERCC6 COPA MYO9B NOC2L TRIP12 MAP3K1 FXR1 MCM9 EIF4G1 SNRNP200	3.11e-05	759	174	14	35915203
Pubmed	Fukutin-related protein alters the deposition of laminin in the eye and brain.	LAMA1 LAMA3 DAG1	3.39e-05	13	174	3	21900571
Pubmed	Systematic Analysis of Human Protein Phosphatase Interactions and Dynamics.	FLII SIKE1 MYO9A ANKLE2 CTTNBP2NL STRIP1 CEP350 PHKG2 SF3B1 SLC4A1AP POTEI SNRNP200	3.47e-05	573	174	12	28330616
Pubmed	Identification of dynein heavy chain genes expressed in human and mouse testis: chromosomal localization of an axonemal dynein gene.	DNAH12 DNAH17 DNAH11	4.30e-05	14	174	3	9373155
Pubmed	Genome-wide CRISPR screens identify novel regulators of wild-type and mutant p53 stability.	MYO9A MYO9B KDM5C DDX11 BLK KANSL3 POTEE CCDC88A NAV1 POTEI PCM1 PCNT	4.45e-05	588	174	12	38580884
Pubmed	Fibril treatment changes protein interactions of tau and α-synuclein in human neurons.	COPA SARM1 NBEA TRIP12 TRIM3 STRIP1 GDAP1L1 FXR1 APPL2 NAV1 PRPS1	4.60e-05	498	174	11	36634849
Pubmed	Kelch Domain of Gigaxonin Interacts with Intermediate Filament Proteins Affected in Giant Axonal Neuropathy.	DNHD1 POTEF SPTAN1 RTTN ZZEF1 CACNA1H PCNT	4.62e-05	187	174	7	26460568
Pubmed	Identification of a novel actin isoform in hepatocellular carcinoma.	POTEF POTEE POTEI	5.36e-05	15	174	3	16824795
Pubmed	Ex vivo Quantitative Proteomic Analysis of Serotonin Transporter Interactome: Network Impact of the SERT Ala56 Coding Variant.	FLII DLGAP2 MYO9A GABBR2 FXR1 APPL2 TRIM32 AMOTL1 CCDC15 CAMSAP2	6.70e-05	430	174	10	32581705
Pubmed	Frequent overexpression of the genes FXR1, CLAPM1 and EIF4G located on amplicon 3q26-27 in squamous cell carcinoma of the lung.	FXR1 EIF4G1	7.44e-05	3	174	2	17290396
Pubmed	Non-muscle alpha-dystroglycan is involved in epithelial development.	LAMA1 DAG1	7.44e-05	3	174	2	7790379
Pubmed	SARM1 depletion rescues NMNAT1-dependent photoreceptor cell death and retinal degeneration.	SARM1 NMNAT3	7.44e-05	3	174	2	33107823
Pubmed	Expression of phosphoribosyl pyrophosphate synthetase genes in U87 glioma cells with ERN1 knockdown: effect of hypoxia and endoplasmic reticulum stress.	PRPS2 PRPS1	7.44e-05	3	174	2	25816608
Pubmed	POTEE drives colorectal cancer development via regulating SPHK1/p65 signaling.	POTEE SPHK1	7.44e-05	3	174	2	31723122
Pubmed	Partial reconstitution of mammalian phosphoribosylpyrophosphate synthetase in Escherichia coli cells. Coexpression of catalytic subunits with the 39-kDa associated protein leads to formation of soluble multimeric complexes of various compositions.	PRPS2 PRPS1	7.44e-05	3	174	2	9366267
Pubmed	A complex of synaptic adhesion molecule CADM1, a molecule related to autism spectrum disorder, with MUPP1 in the cerebellum.	MPDZ GABBR2	7.44e-05	3	174	2	22994563
Pubmed	Mouse large can modify complex N- and mucin O-glycans on alpha-dystroglycan to induce laminin binding.	LAMA1 DAG1	7.44e-05	3	174	2	15788414
Pubmed	Evolution and expression of chimeric POTE-actin genes in the human genome.	POTEF POTEE	7.44e-05	3	174	2	17101985
Pubmed	Dystroglycan is a binding protein of laminin and merosin in peripheral nerve.	LAMA1 DAG1	7.44e-05	3	174	2	7925941
Pubmed	Laminin alpha1 chain mediated reduction of laminin alpha2 chain deficient muscular dystrophy involves integrin alpha7beta1 and dystroglycan.	LAMA1 DAG1	7.44e-05	3	174	2	16504180
Pubmed	Molecular mechanism of c-Myc and PRPS1/2 against thiopurine resistance in Burkitt's lymphoma.	PRPS2 PRPS1	7.44e-05	3	174	2	32391636
Pubmed	Cloning of cDNAs for human phosphoribosylpyrophosphate synthetases 1 and 2 and X chromosome localization of PRPS1 and PRPS2 genes.	PRPS2 PRPS1	7.44e-05	3	174	2	1962753
Pubmed	Brain alpha-dystroglycan displays unique glycoepitopes and preferential binding to laminin-10/11.	LAMA1 DAG1	7.44e-05	3	174	2	16709410
Pubmed	Arginylation regulates purine nucleotide biosynthesis by enhancing the activity of phosphoribosyl pyrophosphate synthase.	PRPS2 PRPS1	7.44e-05	3	174	2	26175007
Pubmed	HectD1 controls hematopoietic stem cell regeneration by coordinating ribosome assembly and protein synthesis.	CTU2 COPA TRMT2A EIF4G1 EXOC2	7.85e-05	87	174	5	33711283
Pubmed	LMBR1L regulates lymphopoiesis through Wnt/β-catenin signaling.	EXOC6 TBRG4 COPA UBE4B NOC2L SARM1 DAG1 ANKLE2 TRIP12 ANKRD13A NAA25 TRIM32 CDIPT EIF4G1 NUP188	8.52e-05	942	174	15	31073040
Pubmed	Identification of different proteins binding to Na, K-ATPase α1 in LPS-induced ARDS cell model by proteomic analysis.	GTPBP4 COPA TRIP12 MYOF SF3B1 SNRNP200	9.06e-05	144	174	6	35681168
Pubmed	Notch is required for the formation of all nephron segments and primes nephron progenitors for differentiation.	LAMA1 NPHS2 MAFB	9.50e-05	18	174	3	29113990
Pubmed	Phosphoproteome analysis of the human mitotic spindle.	ERCC6 NOC2L CEP350 FAM83D SNRNP200 PCM1 PCNT	9.58e-05	210	174	7	16565220
Pubmed	LGALS3BP regulates centriole biogenesis and centrosome hypertrophy in cancer cells.	SIKE1 SPTAN1 LAMA3 ANKLE2 CTTNBP2NL GALNT18 CEP350 PHKG2 CCDC88A TRIM32 SNRNP200 PCM1	9.79e-05	639	174	12	23443559
Pubmed	Requirement for the Mitochondrial Pyruvate Carrier in Mammalian Development Revealed by a Hypomorphic Allelic Series.	PRPS2 HK3 PRPS1L1 PHKG2 PRPS1	1.08e-04	93	174	5	27215380
Pubmed	An organelle-specific protein landscape identifies novel diseases and molecular mechanisms.	PRPS2 MTA2 EXOC6 COX6C NCAPH2 ANKLE2 ANKRD13A FANCB PHKG2 CCDC88A TRIM32 NEK8 AMOTL1 NAV1 EXOC2 EIF2AK1 CAMSAP2 SNRNP200	1.21e-04	1321	174	18	27173435
Pubmed	GRWD1 regulates ribosomal protein L23 levels via the ubiquitin-proteasome system.	COPA NOC2L SPTAN1 SF3B1 CDIPT EIF4G1 SNRNP200	1.32e-04	221	174	7	29991511
Pubmed	Hook3 interacts with PCM1 to regulate pericentriolar material assembly and the timing of neurogenesis.	PCM1 PCNT	1.48e-04	4	174	2	20152126
Pubmed	Nudel contributes to microtubule anchoring at the mother centriole and is involved in both dynein-dependent and -independent centrosomal protein assembly.	PCM1 PCNT	1.48e-04	4	174	2	16291865
Pubmed	The Bardet-Biedl protein BBS4 targets cargo to the pericentriolar region and is required for microtubule anchoring and cell cycle progression.	MAFB PCM1	1.48e-04	4	174	2	15107855
Pubmed	TRIP12 functions as an E3 ubiquitin ligase of APP-BP1.	UBE4B TRIP12	1.48e-04	4	174	2	18627766
Pubmed	EB1 is required for primary cilia assembly in fibroblasts.	CEP350 PCNT	1.48e-04	4	174	2	17600711
Pubmed	BIG1 is a binding partner of myosin IXb and regulates its Rho-GTPase activating protein activity.	MYO9A MYO9B	1.48e-04	4	174	2	15644318
Pubmed	TRIM-NHL proteins in development and disease.	TRIM3 TRIM32	1.48e-04	4	174	2	26514622
Pubmed	Molecular recognition by LARGE is essential for expression of functional dystroglycan.	LAMA1 DAG1	1.48e-04	4	174	2	15210115
Pubmed	Integration of Cistromic and Transcriptomic Analyses Identifies Nphs2, Mafb, and Magi2 as Wilms' Tumor 1 Target Genes in Podocyte Differentiation and Maintenance.	NPHS2 MAFB	1.48e-04	4	174	2	25556170
Pubmed	Defining the proximal interaction networks of Arf GTPases reveals a mechanism for the regulation of PLD1 and PI4KB.	TCF12 NBEA TRIP12 STRIP1 CEP350 CCDC88A SF3B1 AMOTL1 GCC1 SCLT1 SNRNP200 PCM1 PRPS1	1.58e-04	777	174	13	35844135
Pubmed	Comparative interactome analysis of α-arrestin families in human and Drosophila.	COPA KDM5C LAMA1 TRIM3 NEDD4 ANKRD13A ATP11C SNRNP200	1.92e-04	313	174	8	38270169
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	SARM1 CCDC85A CEP350 MYOF VPS13D DNAH17 KLHL14 EIF2AK1 SNRNP200 DOP1A	2.04e-04	493	174	10	15368895
Pubmed	Targeting USP10 induces degradation of oncogenic ANLN in esophageal squamous cell carcinoma.	PRPS2 MTA2 GTPBP4 FLII ERCC6 COPA NOC2L SPTAN1 LAMA3 TRIP12 MYOF FXR1 SF3B1 AMOTL1 EIF4G1 NAV1 SNRNP200	2.05e-04	1257	174	17	36526897
Pubmed	Neuron-specific protein network mapping of autism risk genes identifies shared biological mechanisms and disease-relevant pathologies.	PITPNM2 FLII DLGAP2 KCNH7 SPTAN1 DAG1 NBEA GABBR2 ANKLE2 AKR7A2 CCDC88A SF3B1 CNTNAP2 NAV1 CAMSAP2 PCM1	2.07e-04	1139	174	16	36417873
Pubmed	Identifying biological pathways that underlie primordial short stature using network analysis.	MTA2 GTPBP4 FLII COPA MYO9B NOC2L TRIP12 CEP350 FXR1 SF3B1 EIF4G1 NUP188 SNRNP200 PCM1 PCNT	2.11e-04	1024	174	15	24711643
Pubmed	FBXO22 promotes leukemogenesis by targeting BACH1 in MLL-rearranged acute myeloid leukemia.	FLII ERCC6 KDM5C OBSCN TOGARAM2 NBEA TRIP12 VPS13D DNAH12 SLC4A1AP	2.17e-04	497	174	10	36774506
Pubmed	Linkage of phosphoribosylpyrophosphate synthetases 1 and 2, Prps1 and Prps2, on the mouse X chromosome.	PRPS2 PRPS1	2.46e-04	5	174	2	7849396
Pubmed	Expression and distribution of laminin alpha1 and alpha2 chains in embryonic and adult mouse tissues: an immunochemical approach.	LAMA1 LAMA3	2.46e-04	5	174	2	11969289
Pubmed	Iron metabolism mutant hbd mice have a deletion in Sec15l1, which has homology to a yeast gene for vesicle docking.	EXOC6 MYOF	2.46e-04	5	174	2	16289749
Pubmed	Frameshift mutations of ubiquitination-related genes HERC2, HERC3, TRIP12, UBE2Q1 and UBE4B in gastric and colorectal carcinomas with microsatellite instability.	UBE4B TRIP12	2.46e-04	5	174	2	22124266
Pubmed	The centriolar satellite protein Cep131 is important for genome stability.	PCM1 PCNT	2.46e-04	5	174	2	22797915
Pubmed	Differential expression of five laminin alpha (1-5) chains in developing and adult mouse kidney.	LAMA1 LAMA3	2.46e-04	5	174	2	9415429
Pubmed	Complete sequence, recombinant analysis and binding to laminins and sulphated ligands of the N-terminal domains of laminin alpha3B and alpha5 chains.	LAMA1 LAMA3	2.46e-04	5	174	2	11829758
Pubmed	Involvement of Exoc3l, a protein structurally related to the exocyst subunit Sec6, in insulin secretion.	EXOC6 EXOC2	2.46e-04	5	174	2	18480549
Pubmed	Tumor suppressor function of laminin-binding alpha-dystroglycan requires a distinct beta3-N-acetylglucosaminyltransferase.	LAMA1 DAG1	2.46e-04	5	174	2	19587235
Pubmed	Architecture, substructures, and dynamic assembly of STRIPAK complexes in Hippo signaling.	SIKE1 STRIP1	2.46e-04	5	174	2	30622739
Pubmed	Genomic characterization of the lysophosphatidic acid receptor gene, lp(A2)/Edg4, and identification of a frameshift mutation in a previously characterized cDNA.	MYO9B LPAR2	2.46e-04	5	174	2	10729222
Interaction	EXOC1 interactions	EXOC6 SIKE1 SPTAN1 POTEE CCDC88A TRIM32 KXD1 EXOC2 PCNT	3.22e-06	143	168	9	int:EXOC1
GeneFamily	Myosins, class IX	MYO9A MYO9B	2.40e-05	2	89	2	1103
GeneFamily	Ankyrin repeat domain containing\|POTE ankyrin domain containing	POTEF POTEE POTEI	3.18e-05	13	89	3	685
GeneFamily	Dyneins, axonemal	DNAH12 DNAH17 DNAH11	7.46e-05	17	89	3	536
GeneFamily	Protein phosphatase catalytic subunits\|STRIPAK complex	SIKE1 CTTNBP2NL STRIP1	1.24e-04	20	89	3	1371
GeneFamily	Exocyst complex	EXOC6 EXOC2	8.43e-04	9	89	2	1055
GeneFamily	Ankyrin repeat domain containing	POTEF ANKLE2 ANKRD13A POTEE ANKRD60 POTEI	1.24e-03	242	89	6	403
GeneFamily	Laminin subunits	LAMA1 LAMA3	1.53e-03	12	89	2	626
GeneFamily	GATA zinc finger domain containing\|Myb/SANT domain containing	MTA2 RERE	2.41e-03	15	89	2	82
ToppCell	COVID-19-Heart-EC_2\|Heart / Disease (COVID-19 only), tissue and cell type	EXOC6 RAPGEF5 LRRC32 TNFRSF10A CTTNBP2NL GALNT18 CCDC85A MMRN2	7.21e-07	187	173	8	40ffc06a3e3251d9b12da390210d3e045af7537a
ToppCell	368C-Lymphocytic-CD4_T-cell-CD4+_Naive_T_cell_/_CD4+_Trm_cell\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	EFCAB5 MAN2A2 RTTN CHST6 ZFR2 PGAP1 EIF4G1	2.23e-06	152	173	7	ca23261d8ef263cc697b8d7e7cb2afec8bc564f2
ToppCell	368C-Lymphocytic-CD4_T-cell-CD4+_Naive_T_cell_/_CD4+_Trm_cell\|CD4_T-cell / Donor, Lineage, Cell class and subclass (all cells)	EFCAB5 MAN2A2 RTTN CHST6 ZFR2 PGAP1 EIF4G1	3.13e-06	160	173	7	19105debef96ea0c267d6a1d332303ec668ae47e
ToppCell	PCW_13-14-Epithelial-Epithelial_ciliated\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	MAT1A TOGARAM2 RIBC1 LRRC43 DNAH12 DLEC1 ODAD3	5.65e-06	175	173	7	b1369d2b74f461e6822d0c33e9b50fe0dfbceb54
ToppCell	PCW_13-14-Epithelial-Epithelial_ciliated-epi_ciliated_(14)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	MAT1A TOGARAM2 RIBC1 LRRC43 DNAH12 DLEC1 ODAD3	5.65e-06	175	173	7	c82ec6deb6ccdd991a69a62b6d62d5b14c803d7a
ToppCell	normal_Pleural_Fluid-Myeloid_cells-CD163+CD14+_DCs\|normal_Pleural_Fluid / Location, Cell class and cell subclass	C3orf33 SPHK1 TGFBRAP1 SHPK ATP11C CAMSAP2 POFUT2	5.86e-06	176	173	7	7a74217b7fa1032b918f00a3972dff5fab74671a
ToppCell	PBMC-Convalescent-Lymphocyte-B-B_cell-B_intermediate-B_intermediate-1\|Convalescent / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	PPM1J CPNE5 CCDC85A BLK DNAH12 KLHL14 DNAH11	6.32e-06	178	173	7	812e261d9cbdc74fafe3c5c3422151c1cfacb22d
ToppCell	Fetal_29-31_weeks-Epithelial-ciliated_cell-D062\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	MAT1A TOGARAM2 CCDC175 DNAH12 DLEC1 ODAD3 DNAH11	6.32e-06	178	173	7	de5d50d7ca9ee9eb62f50c88a0c6d47f0694b2e6
ToppCell	COVID-19-kidney-AQP1+SLC14A1+EC\|COVID-19 / Disease (COVID-19 only), tissue and cell type	EXOC6 RAPGEF5 LRRC32 CPNE5 CTTNBP2NL GALNT18 NAV1	6.55e-06	179	173	7	1ce8d18f63e8dd2d3db41fbeca4601bd3b305fba
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Renal_corpuscle_epithelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	TOGARAM2 OCA2 CCDC85A NPHS2 FAM180A MAFB AMIGO2	7.57e-06	183	173	7	848fc6dd129150897ee339343e83c645b6e779eb
ToppCell	Children_(3_yrs)-Endothelial-endothelial_cell_of_lymph_vessel-D139\|Children_(3_yrs) / Lineage, Cell type, age group and donor	DLGAP2 MPDZ CPNE5 GALNT18 NEDD4 SPHK1 KLHL14	9.02e-06	188	173	7	aeecbc057dc823f8fcea8a98f18d213bacc7f4db
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Descending_Vasa_Recta_Endothelial_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	EXOC6 RAPGEF5 LRRC32 LAMA3 CCDC85A MMRN2 NAV1	1.03e-05	192	173	7	56b021c297a21dff357531f21e2464f85186106d
ToppCell	COVID-19-Endothelial_cells-Inflamed_endothelial_cells\|COVID-19 / group, cell type (main and fine annotations)	PITPNM2 RAPGEF5 LRRC32 GABBR2 GALNT18 CCDC85A NEDD4	1.07e-05	193	173	7	979ebefa527f86bebeea5d94e626ee6c1cc7d53b
ToppCell	PCW_10-12-Endothelial-Endothelial_immature-endo_immature4_(5)\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	PITPNM2 RAPGEF5 LRRC32 TNFRSF10A GALNT18 CCDC85A MMRN2	1.11e-05	194	173	7	53a5e8863d79a052dff0758f389be5ac3883c721
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Descending_Vasa_Recta_Endothelial_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	EXOC6 RAPGEF5 LAMA3 CTTNBP2NL CCDC85A MMRN2 NAV1	1.14e-05	195	173	7	6bdef651cf73d7381e5012d0eb3c809138fb6b92
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Descending_Vasa_Recta_Endothelial_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	EXOC6 RAPGEF5 LRRC32 LAMA3 CCDC178 CTTNBP2NL MMRN2	1.14e-05	195	173	7	d35102f95bb1e419d2df05ff0a01b6c5c923acef
ToppCell	PCW_13-14-Endothelial-Endothelial_mature\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	RAPGEF5 LRRC32 TNFRSF10A CPNE5 GALNT18 CCDC85A MMRN2	1.14e-05	195	173	7	31353269591c9eee84872838e91995d4a035da46
ToppCell	PCW_10-12-Endothelial-Endothelial_mature\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	PITPNM2 RAPGEF5 LRRC32 CPNE5 GALNT18 CCDC85A MMRN2	1.18e-05	196	173	7	481d79bdaec069ad2746a28d39eeee8d3edf7305
ToppCell	Epithelial-Epithelial-A_(AT1)\|Epithelial / shred on cell class and cell subclass (v4)	LAMA3 DAG1 CTTNBP2NL GALNT18 TRIM3 SPHK1 CDIPT	1.18e-05	196	173	7	41b21a18125cc95bc8adde3369e4abd029cf137d
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	EXOC6 RAPGEF5 LRRC32 CCDC85A NEDD4 MMRN2 NAV1	1.18e-05	196	173	7	b8f89a50114932c08fc5daac4b549adfe9df8e66
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	EXOC6 RAPGEF5 LRRC32 CCDC85A NEDD4 MMRN2 NAV1	1.18e-05	196	173	7	145fcf73deba9638b391a1af6c39fa205dc9829f
ToppCell	COVID-19-lung-Capillary_1\|COVID-19 / Disease (COVID-19 only), tissue and cell type	PITPNM2 EXOC6 RAPGEF5 LRRC32 GALNT18 CCDC85A NAV1	1.18e-05	196	173	7	ac28e9be288af6f00a841aea4ce4b99aed6b4505
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Endothelial\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	EXOC6 RAPGEF5 LRRC32 CCDC85A NEDD4 MMRN2 NAV1	1.18e-05	196	173	7	d0ff1082898d2db47c88d2678466514e9e9193d3
ToppCell	PCW_10-12-Endothelial-Endothelial_immature-endo_immature3_(11)\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	PITPNM2 RAPGEF5 LRRC32 TNFRSF10A GALNT18 CCDC85A MMRN2	1.22e-05	197	173	7	a7922f65a8af4a773e4ce80114e4d895a594fa2f
ToppCell	COVID-19-lung-Capillary_1\|lung / Disease (COVID-19 only), tissue and cell type	PITPNM2 RAPGEF5 LRRC32 GALNT18 CCDC85A NEDD4 NAV1	1.22e-05	197	173	7	7e86ff9dafcbaaa7464d61484dd48bfeb7eae6e4
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	EXOC6 RAPGEF5 LRRC32 CCDC85A NEDD4 MMRN2 NAV1	1.26e-05	198	173	7	b027a141ab531d0f5d6a26811a53427e7b0771dd
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	EXOC6 RAPGEF5 LRRC32 CCDC85A NEDD4 MMRN2 NAV1	1.26e-05	198	173	7	953630dbe3154b1b102b87de0feca2cbf124eabe
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	EXOC6 RAPGEF5 LRRC32 CCDC85A NEDD4 MMRN2 NAV1	1.26e-05	198	173	7	8e45551224fbb30c0658ad47dd98335ecf165437
ToppCell	LPS_IL1RA-Endothelial-Endothelial-Gen_Cap\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	PITPNM2 RAPGEF5 SPTAN1 MPDZ GALNT18 NEDD4 PCNT	1.35e-05	200	173	7	dccec522ab0d7fff62ad6273b02aa9022dbbb8eb
ToppCell	Control_saline-Endothelial-Endothelial-Gen_Cap\|Control_saline / Treatment groups by lineage, cell group, cell type	PITPNM2 EXOC6 RAPGEF5 SPTAN1 LRRC32 MPDZ GALNT18	1.35e-05	200	173	7	3b97920e1e6e2f09ddba2a861baa9c00c2970f4c
ToppCell	LPS_only-Epithelial_airway-Ciliated_cells-Ciliated\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	MAT1A TOGARAM2 LRRC43 DLEC1 ODAD3 DNAH11	3.11e-05	154	173	6	9ca71d440c4f87781e6525b8141e7d8d470b6a8e
ToppCell	LPS_only-Epithelial_airway-Ciliated_cells\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	MAT1A TOGARAM2 LRRC43 DLEC1 ODAD3 DNAH11	3.11e-05	154	173	6	58072ce422d09f2de602580325eaac6c4ec6c136
ToppCell	368C-Myeloid-Macrophage-FABP4+_Macrophage_2\|Macrophage / Donor, Lineage, Cell class and subclass (all cells)	PITPNM2 OCA2 BLK SHPK FAM180A POFUT2	4.57e-05	165	173	6	3d2acdae0dd2b79a15f74158e8e566ce22b4218e
ToppCell	3'_v3-bone_marrow-Lymphocytic_B-GC_B_(I)\|bone_marrow / Manually curated celltypes from each tissue	RTTN TMEM185A STRIP1 BLK KANSL3 PGAP1	5.95e-05	173	173	6	67f0f0bf88eab69987b71d96b864ed2b14975adb
ToppCell	droplet-Marrow-nan-18m-Myeloid-basophil\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CPNE5 ZZEF1 TRIM3 CEP350 APPL2 MCM9	6.14e-05	174	173	6	55cc8300489d11322724159ec7d0e1d32a702e91
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	MYO9A GALNT18 MAP3K1 NMNAT3 DNAH17 DNAH11	6.54e-05	176	173	6	327a3e81b724252e36d786de92a3ffd721ea6d7b
ToppCell	Fetal_29-31_weeks-Endothelial-endothelial_cell_of_artery\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	EXOC6 RAPGEF5 LRRC32 CTTNBP2NL GALNT18 MMRN2	6.75e-05	177	173	6	5ff8dcfb030312126695d53a026d2e104a401b83
ToppCell	facs-Lung-EPCAM-18m-Endothelial\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RAPGEF5 LRRC32 GALNT18 FANCB MMRN2 AMIGO2	6.75e-05	177	173	6	2433924dcb085ebbe2545d476ebd7ee68e6092fb
ToppCell	15-Airway-Epithelial-Multiciliated_precursor\|Airway / Age, Tissue, Lineage and Cell class	MAT1A RIBC1 DNAH12 DNAH17 DLEC1 DNAH11	6.96e-05	178	173	6	d8e0a696bdd6af6422d72af0413f9dbd6bc02afa
ToppCell	COVID-19-Heart-EC_2\|COVID-19 / Disease (COVID-19 only), tissue and cell type	RAPGEF5 LRRC32 CTTNBP2NL GALNT18 CCDC85A MMRN2	7.18e-05	179	173	6	2a53d94f6c30bf887dfe88f1693ea057218c852d
ToppCell	facs-Lung-EPCAM-18m-Endothelial-endothelial_cell_of_lung\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RAPGEF5 LRRC32 GALNT18 FANCB PRDM11 MMRN2	7.41e-05	180	173	6	082c6116e0bbba8d9a3a82d14af55bdc8990c8c0
ToppCell	facs-Lung-EPCAM-18m-Endothelial-Capillary_endothelial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RAPGEF5 LRRC32 GALNT18 FANCB PRDM11 MMRN2	7.41e-05	180	173	6	53043d764fad9ac33ee40e356e562e759931adef
ToppCell	COVID-19-Endothelial_cells-Capillary_endothelial_cells\|COVID-19 / group, cell type (main and fine annotations)	PITPNM2 RAPGEF5 GABBR2 GALNT18 CCDC85A NEDD4	7.64e-05	181	173	6	c5f9c92af1384d9089c65afdf41c6feb8345a3ae
ToppCell	Adult-Epithelial-ciliated_cell-D122\|Adult / Lineage, Cell type, age group and donor	MAT1A TOGARAM2 DNAH12 DLEC1 ODAD3 DNAH11	7.87e-05	182	173	6	7ded554a4b441e6496db673ba206c0d76ccad7d9
ToppCell	TCGA-Lung-Primary_Tumor-Lung_Carcinoma-Lung_Squamous_Cell_Carcinoma-3\|TCGA-Lung / Sample_Type by Project: Shred V9	NMNAT3 FXR1 PGAP1 EIF4G1 CNTNAP2 FAM83D	8.36e-05	184	173	6	ea4ccebe2d54279fcc517e4f0bfa652b91a808bb
ToppCell	PCW_10-12-Endothelial-Endothelial_mature-endo_arterial_(9)\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	EXOC6 RAPGEF5 LRRC32 CPNE5 GALNT18 MMRN2	8.36e-05	184	173	6	a809b0fa52df8a159f60f87eefcef61220af5e34
ToppCell	COVID-19-Endothelial_cells-Arterial_endothelial_cells\|COVID-19 / group, cell type (main and fine annotations)	EXOC6 RAPGEF5 LRRC32 CTTNBP2NL GALNT18 MMRN2	8.36e-05	184	173	6	0f19494789f38ab1a420545e15e748ca7eb345c3
ToppCell	droplet-Limb_Muscle-nan-3m-Macroglial-nan\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FAM184B DAG1 CPNE5 STRIP1 C3orf33 SHPK	8.61e-05	185	173	6	554c5d812197fbf66bf279fcc953277e926ade15
ToppCell	Adult-Epithelial-ciliated_cell-D175\|Adult / Lineage, Cell type, age group and donor	TOGARAM2 CCDC175 DNAH12 DLEC1 ODAD3 DNAH11	8.61e-05	185	173	6	30f4980dee6cd5959655f8d74049f3bfb5312611
ToppCell	LPS-IL1RA+antiTNF-Endothelial-Endothelial-Activated_Alv_Cap\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	PITPNM2 KCNH7 RAPGEF5 GALNT18 CCDC85A NEDD4	9.14e-05	187	173	6	f3397dbc23b6c2f24e2c1ba887d8f9aef3ee01a1
ToppCell	PCW_07-8.5-Endothelial-Endothelial_mature-endo_capillary_(2)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	PITPNM2 RAPGEF5 LRRC32 TNFRSF10A CCDC85A MMRN2	9.14e-05	187	173	6	106f50ad85a92403037214f0e94702230284837f
ToppCell	COVID-19-lung-Artery_EC\|lung / Disease (COVID-19 only), tissue and cell type	EXOC6 RAPGEF5 LRRC32 CTTNBP2NL GALNT18 MMRN2	9.41e-05	188	173	6	eecd7482b3c97d7f49993cb17edfab30c61232fc
ToppCell	PCW_13-14-Endothelial-Endothelial_immature-endo_immature_arterial2_(6)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	RAPGEF5 LRRC32 CPNE5 GALNT18 CCDC85A MMRN2	9.41e-05	188	173	6	b66f1f08827dd6c48583d871f9f33ea41e48bfb2
ToppCell	Ciliated_cells-B-Donor_07\|World / lung cells shred on cell class, cell subclass, sample id	TOGARAM2 RIBC1 CHST6 DNAH12 DLEC1 DNAH11	9.41e-05	188	173	6	606907c865bd2f11bb6474932716550f7723d858
ToppCell	Fetal_29-31_weeks-Epithelial-lung_neuroendocrine_cell_(PNEC)-D150\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	DLGAP2 KCNH7 BCL2L10 POTEI GOLGA7B AMIGO2	9.41e-05	188	173	6	c4c3b21ab723b0e9beff9ec84f8d68485f771528
ToppCell	PCW_13-14-Endothelial-Endothelial_mature-endo_bronchial_(8)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	PITPNM2 RAPGEF5 LRRC32 TNFRSF10A GALNT18 MMRN2	9.41e-05	188	173	6	986aaf31161ec3d1e6c76ee2dd17f44848a21f7e
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Descending_Vasa_Recta_Endothelial_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	EXOC6 RAPGEF5 LAMA3 CCDC85A MMRN2 NAV1	9.68e-05	189	173	6	6463890d8dbee4bc198f91628a5f784970de786a
ToppCell	Control-Endothelial-Endothelial-Alv_Gen_Intermediate\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	PITPNM2 TNFRSF10A GALNT18 CCDC85A NEDD4 ATP11C	9.68e-05	189	173	6	5d7ae1ead7f4fbaeec26f651833c9c2106e1e4d1
ToppCell	control-Myeloid-CD14_Monocytes_2\|Myeloid / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs	TCF12 COX6C MYOF CCDC88A NAV1 MAFB	9.68e-05	189	173	6	7f78b5bb8195f99b18082cbb612e9199b7a1538c
ToppCell	PCW_10-12-Endothelial-Endothelial_mature-endo_bronchial_(8)\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	PITPNM2 RAPGEF5 LRRC32 TNFRSF10A GALNT18 MMRN2	9.68e-05	189	173	6	033a2be8bbb7bfb437e6f1657b6ca02070c74aa8
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Afferent_/_Efferent_Arteriole_Endothelial_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	EXOC6 LRRC32 CTTNBP2NL CCDC85A MMRN2 NAV1	9.97e-05	190	173	6	bf9bc57a605c7e3979bc4f7260e6fb92c3eb8690
ToppCell	BALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c03-ITGA4\|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)	SPTAN1 MAP3K1 NMNAT3 PGAP1 LPAR2 BRD1	9.97e-05	190	173	6	91ba66d4b56c59523485b17738e93f14bb00afa4
ToppCell	COVID-19-lung-Artery_EC\|COVID-19 / Disease (COVID-19 only), tissue and cell type	EXOC6 RAPGEF5 LRRC32 CTTNBP2NL GALNT18 CCDC85A	9.97e-05	190	173	6	07b675befcd1d0a9c90cb17b5d22323468325d51
ToppCell	Severe-Lymphoid-NK-Treg\|Severe / Condition, Lineage, Cell class and cell subclass	SARM1 TMEM185A DDX11 C3orf33 GOLGA7B AMIGO2	9.97e-05	190	173	6	e67803bf55a3f8e47a69ff1829c9100f870d7527
ToppCell	PCW_10-12-Endothelial-Endothelial_immature-endo_immature_arterial2_(6)\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	RAPGEF5 LRRC32 CPNE5 GALNT18 CCDC85A MMRN2	9.97e-05	190	173	6	7ba2be2630183df86de21689289a8620a4cd507e
ToppCell	droplet-Lung-1m-Endothelial-venous_endothelial\|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	LAMA1 OBSCN NEDD4 AMOTL1 MMRN2 AMIGO2	1.06e-04	192	173	6	1990dc8a81594018a5bf596be99d0b5f0af0f58f
ToppCell	COVID-19-kidney-AQP1+PLVAP+EC\|COVID-19 / Disease (COVID-19 only), tissue and cell type	PITPNM2 RAPGEF5 LRRC32 CPNE5 GALNT18 NAV1	1.06e-04	192	173	6	27ff3621e177e7932dd44dd6baa81551ea75a874
ToppCell	human_hepatoblastoma-Endothelial_cells\|human_hepatoblastoma / Sample and Cell Type and Tumor Cluster (all cells)	RAPGEF5 CPNE5 GALNT18 CCDC85A NAV1 ATP11C	1.06e-04	192	173	6	e09f609fed033a25baacaf4a07bbbae1076da366
ToppCell	droplet-Lung-1m-Endothelial-venous_endothelial-vein_endothelial_cell-vein_endothelial_cell\|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	LAMA1 OBSCN NEDD4 AMOTL1 MMRN2 AMIGO2	1.06e-04	192	173	6	845cc9c18b4436b07dd3ce7980052683937546d2
ToppCell	droplet-Lung-1m-Endothelial-venous_endothelial-vein_endothelial_cell\|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	LAMA1 OBSCN NEDD4 AMOTL1 MMRN2 AMIGO2	1.06e-04	192	173	6	c72a082c93a8825adbfef37f889ba3a7052f201b
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	EXOC6 RAPGEF5 LRRC32 CCDC85A MMRN2 NAV1	1.06e-04	192	173	6	28eb3a5728e8901bcb5ba12f6b009f41b065fa37
ToppCell	nucseq-Endothelial-Endothelial_Vascular-Endothelial_capillary\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	PITPNM2 RAPGEF5 LRRC32 GALNT18 NEDD4 NAV1	1.09e-04	193	173	6	f582e939e3e08a8a3f71deec78c33715be8faa51
ToppCell	PCW_05-06-Endothelial-Endothelial_mature-endo_capillary_(2)\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	PITPNM2 RAPGEF5 LRRC32 GALNT18 CCDC85A MMRN2	1.09e-04	193	173	6	4f38aae346ea3b4258744e9dc1e5aeb4fea13d06
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Descending_Vasa_Recta_Endothelial_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	EXOC6 RAPGEF5 CTTNBP2NL CCDC85A MMRN2 NAV1	1.09e-04	193	173	6	2e72309607902dabe3218888b22a77fe941f3570
ToppCell	PCW_10-12-Endothelial-Endothelial_cycling-endo_proliferating1_(10)\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	PITPNM2 RAPGEF5 LRRC32 TNFRSF10A GALNT18 MMRN2	1.09e-04	193	173	6	643f992dbce639e7d147924d8b8f455fcebf215a
ToppCell	Control-Endothelial-Endothelial-Gen_Cap\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	PITPNM2 EXOC6 GALNT18 CCDC85A NEDD4 NAV1	1.09e-04	193	173	6	e1d546165dcc2392f540162206852c4717d7306f
ToppCell	Fetal_29-31_weeks-Endothelial-capillary_endothelial_cell_(Cap1)-D088\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	PITPNM2 RAPGEF5 LRRC32 GALNT18 CCDC85A NAV1	1.09e-04	193	173	6	ad2df9b77999780860141be6ec366afc0172a331
ToppCell	PCW_13-14-Endothelial-Endothelial_immature-endo_immature4_(5)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	RAPGEF5 LRRC32 TNFRSF10A GALNT18 CCDC85A MMRN2	1.09e-04	193	173	6	01c71aa48875b5ad6c50cc810a72862e72f26ad0
ToppCell	PCW_13-14-Endothelial-Endothelial_mature-endo_venous_(13)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	RAPGEF5 LRRC32 CPNE5 CCDC85A SPHK1 MMRN2	1.09e-04	193	173	6	84d1c1b7d3a1cb80f175527e3c89a2c3da7657f7
ToppCell	PCW_07-8.5-Endothelial-Endothelial_mature\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	RAPGEF5 LRRC32 TNFRSF10A CPNE5 CCDC85A MMRN2	1.12e-04	194	173	6	8c88a0ddd61ad900426e312ca4ab13061c0380b8
ToppCell	LPS-IL1RA-Endothelial\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	PITPNM2 RAPGEF5 GALNT18 CCDC85A NEDD4 NAV1	1.12e-04	194	173	6	43f92b0533e26633dc94cce554045d641ef8fd76
ToppCell	PCW_13-14-Endothelial-Endothelial_immature-endo_immature_arterial1_(12)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	RAPGEF5 LRRC32 TNFRSF10A CPNE5 GALNT18 MMRN2	1.12e-04	194	173	6	32ba2cf9b8726bc3c6e9dc24b54d22ff188bb12b
ToppCell	LPS-IL1RA-Endothelial-Endothelial\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	PITPNM2 RAPGEF5 GALNT18 CCDC85A NEDD4 NAV1	1.12e-04	194	173	6	1d39d968730a7e85b6161c1c8a6bd38afe9bcad7
ToppCell	LPS_only-Endothelial\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	PITPNM2 RAPGEF5 GALNT18 CCDC85A NEDD4 NAV1	1.12e-04	194	173	6	58f069efdefa0366033764446b9d6ffd4a17807e
ToppCell	LPS_only-Endothelial-Endothelial\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	PITPNM2 RAPGEF5 GALNT18 CCDC85A NEDD4 NAV1	1.12e-04	194	173	6	bfd92ec75facb0ba55c31e5f2e089d983b3d0169
ToppCell	3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.3.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	TOGARAM2 NBEA DNAH12 SHOC1 DLEC1 DNAH11	1.12e-04	194	173	6	4a2c127c90d1fefe604fcb9e796577d21b489dd6
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	EXOC6 RAPGEF5 LRRC32 CCDC85A MMRN2 NAV1	1.12e-04	194	173	6	b0c15e7e4bcf30856fb628dedd7ba82df33489f5
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Ascending_Vasa_Recta_Endothelial_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	RAPGEF5 LRRC32 CCDC85A NEDD4 MMRN2 NAV1	1.12e-04	194	173	6	fa6d51f36a3dae8763a595c20892987ed454c0f0
ToppCell	wk_15-18-Epithelial-Proximal_epithelial-Ciliated\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	TOGARAM2 RIBC1 LRRC43 DNAH12 DLEC1 DNAH11	1.15e-04	195	173	6	cfcf554b436083179dea1d6fd6e3a800ea2430fe
ToppCell	PCW_10-12-Endothelial-Endothelial_immature-endo_immature_arterial1_(12)\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	RAPGEF5 LRRC32 TNFRSF10A CPNE5 GALNT18 MMRN2	1.15e-04	195	173	6	3826bfafe85f8aa9a508202ceb2b02e81b090498
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Endothelial\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	EXOC6 RAPGEF5 LRRC32 CCDC85A MMRN2 NAV1	1.18e-04	196	173	6	8ad8efb631164b46f0c082572270188e5ead20bf
ToppCell	PCW_10-12-Endothelial-Endothelial_mature-endo_capillary_(2)\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	PITPNM2 RAPGEF5 LRRC32 GALNT18 CCDC85A MMRN2	1.18e-04	196	173	6	2a2a93b89dcb98043cb1f8b422ac8c55e2edc37b
ToppCell	PCW_13-14-Endothelial\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	RAPGEF5 LRRC32 TNFRSF10A GALNT18 CCDC85A MMRN2	1.18e-04	196	173	6	7286de29a34e13834cd6347c67a1443897fa4ade
ToppCell	PCW_13-14-Endothelial-Endothelial_cycling-endo_proliferating1_(10)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	PITPNM2 RAPGEF5 LRRC32 TNFRSF10A GALNT18 MMRN2	1.18e-04	196	173	6	b826dce5b3daa8eb3d4a530b9564de58d9ce3767
ToppCell	PCW_10-12-Endothelial-Endothelial_immature-endo_immature1_(0)\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	PITPNM2 RAPGEF5 LRRC32 GALNT18 CCDC85A MMRN2	1.18e-04	196	173	6	29ed8b1c4cd730db8632fde6eece404f1883a86d
ToppCell	PCW_10-12-Endothelial-Endothelial_immature\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	RAPGEF5 LRRC32 TNFRSF10A GALNT18 CCDC85A MMRN2	1.18e-04	196	173	6	c65b8c7ea34a21897c390e6fb42ee8ca41e9c976
ToppCell	Epithelial-A_(AT1)\|World / shred on cell class and cell subclass (v4)	LAMA3 DAG1 CTTNBP2NL TRIM3 NRBP2 SPHK1	1.18e-04	196	173	6	484bbc6b1f58bc260964babb949d14f5df101393
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Endothelial-blood_vessel_endothelial_cell_of_kidney\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	RAPGEF5 LRRC32 CPNE5 GALNT18 MMRN2 NAV1	1.18e-04	196	173	6	d37f714d4fb57e958f3738fdda085560813e5bb5
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	EXOC6 RAPGEF5 LRRC32 CCDC85A MMRN2 NAV1	1.18e-04	196	173	6	9606ea7e42f707e69ea891b3521037613b9675f5
ToppCell	PCW_10-12-Endothelial-Endothelial_immature-endo_immature_venous_(4)\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	RAPGEF5 LRRC32 TNFRSF10A GALNT18 CCDC85A MMRN2	1.18e-04	196	173	6	81278e696d823744267d6315c4d42799c4ea0b2c
Drug	Primaquine diphosphate [63-45-6]; Down 200; 8.8uM; MCF7; HT_HG-U133A	SIKE1 COPA KDM5C MPDZ NCAPH2 FXR1 PGAP1 CCDC15 EIF2AK1 ULK2	1.67e-06	186	173	10	3279_DN
Drug	Lobelanidine hydrochloride [6112-86-3]; Up 200; 10.6uM; MCF7; HT_HG-U133A	BCL2L10 SARM1 GABBR2 TRIM3 KANSL3 MYOF VPS13D CCDC88A CNTNAP2 CACNA1H	2.56e-06	195	173	10	2897_UP
Drug	PAPM/BP	BCL2L10 PRPS1L1 CDIPT	4.26e-06	5	173	3	CID000115235
Drug	methyl iodoacetate	PRPS2 PRPS1L1 PRPS1	8.48e-06	6	173	3	CID006429536
Drug	APP-MP	PRPS2 PRPS1L1 PRPS1	8.48e-06	6	173	3	CID003081102
Drug	pyrimidine-5-nucleotide	PRPS2 PRPS1L1 PRPS1	8.48e-06	6	173	3	CID000440040
Drug	fructose 3-phosphate	PRPS2 PRPS1L1 AKR7A2 PRPS1	1.42e-05	20	173	4	CID000130872
Drug	Nomifensine maleate [32795-47-4]; Down 200; 11.2uM; PC3; HT_HG-U133A	SIKE1 MAN2A2 UBE4B KDM5C SARM1 MPDZ CEP350 MYOF LPAR2	2.15e-05	198	173	9	2062_DN
Disease	autosomal recessive limb-girdle muscular dystrophy type 2H (implicated_via_orthology)	TRIM3 TRIM32	9.18e-05	3	164	2	DOID:0110282 (implicated_via_orthology)
Disease	Malignant neoplasm of breast	CTU2 ERCC6 ATP7B HK3 SPTAN1 OBSCN OCA2 MAP3K1 NEDD4 PPP1R3A NAA25 FXR1 TRMT2A TAX1BP1 DLEC1 DOP1A PRPS1	1.07e-04	1074	164	17	C0006142
Disease	cortical surface area measurement	PITPNM2 EFCAB5 EXOC6 MYO9B RAPGEF5 TSPY26P MAP3K1 STRIP1 FOCAD CCDC88A SF3B1 NAV1 KIAA1755 YDJC RERE EXOC2 BRD1 DNAH11	5.18e-04	1345	164	18	EFO_0010736
Disease	Colorectal Carcinoma	ERCC6 ATP7B HK3 LAMA1 OBSCN GDAP1L1 EIF4G1 MMRN2 ATP11C CAMSAP2 SNRNP200 PRPS1	5.86e-04	702	164	12	C0009402
Disease	zinc-alpha-2-glycoprotein measurement	SARM1 NPHS2	8.41e-04	8	164	2	EFO_0802228
Disease	Mastocytosis	FTCD FXR1 CACNA1H	1.33e-03	39	164	3	EFO_0009001
Disease	eosinophil percentage of granulocytes	GTPBP4 PPP1R3A KANSL3 RERE EXOC2 D2HGDH	2.03e-03	234	164	6	EFO_0007996
Disease	Amino Acid Metabolism, Inherited Disorders	MAT1A D2HGDH	2.30e-03	13	164	2	C0750905
Disease	Amino Acid Metabolism, Inborn Errors	MAT1A D2HGDH	2.30e-03	13	164	2	C0002514
Disease	response to ketamine, dissociation measurement	TOGARAM2 GDAP1L1	2.30e-03	13	164	2	EFO_0009748, EFO_0009750
Disease	Kartagener syndrome (implicated_via_orthology)	ODAD3 DNAH11	2.67e-03	14	164	2	DOID:0050144 (implicated_via_orthology)
Disease	Autosomal recessive limb-girdle muscular dystrophy	DAG1 TRIM32	2.67e-03	14	164	2	cv:C2931907
Disease	insulin metabolic clearance rate measurement, glucose homeostasis measurement	COX6C ZZEF1	2.67e-03	14	164	2	EFO_0006830, EFO_0006896
Disease	C-reactive protein measurement	OR8U1 UBE4B LRRC43 ZZEF1 TRIP12 MAP3K1 BLK NRBP2 MROH6 SLC4A1AP DNAH17 NKPD1 MAFB RERE DNAH11	3.07e-03	1206	164	15	EFO_0004458
Disease	Down syndrome (implicated_via_orthology)	POFUT2 DOP1A	3.07e-03	15	164	2	DOID:14250 (implicated_via_orthology)
Disease	head and neck squamous cell carcinoma (is_implicated_in)	TNFRSF10A FANCB	3.07e-03	15	164	2	DOID:5520 (is_implicated_in)
Disease	Autistic Disorder	DLGAP2 KDM5C NBEA GABBR2 CNTNAP2 CACNA1H	3.49e-03	261	164	6	C0004352
Disease	2-hydroxyglutarate measurement	D2HGDH PCNT	3.50e-03	16	164	2	EFO_0021506
Disease	autosomal recessive polycystic kidney disease (implicated_via_orthology)	NEK8 SCLT1	3.50e-03	16	164	2	DOID:0110861 (implicated_via_orthology)
Disease	thrombomodulin measurement	LAMA1 NPHS2	3.95e-03	17	164	2	EFO_0007774
Disease	Tourette syndrome, schizophrenia	PITPNM2 RERE	4.43e-03	18	164	2	EFO_0004895, MONDO_0005090
Disease	maximal midexpiratory flow rate	OCA2 GALNT18	5.46e-03	20	164	2	EFO_0004313

Protein segments in the cluster

Peptide	Gene	Start	Entry
RMLSQLAAAESRHRK	CTTNBP2NL	96	Q9P2B4
ERSRHKQLSSMLVLE	CTTNBP2NL	171	Q9P2B4
RRIEVHAIFISNDMR	BRINP3	506	Q76B58
AVRIAFDRAMNHLSR	BRD1	1031	O95696
VHGSQLRRMARLAEL	ANKLE2	921	Q86XL3
MLSAASRVVSRAAVH	AKR7A2	1	O43488
LVALLSSRLMGQHRA	BCL2L10	141	Q9HD36
TDRSLEKAMLSRQHV	AADAC	256	P22760
SLRHRSANMDVLIVL	ATP7B	721	P35670
IEMQAITALAHLRAA	GTPBP4	236	Q9BZE4
SIAHRLNHTLSERQM	ANKRD60	291	Q9BZ19
LNHTLSERQMVLLHR	ANKRD60	296	Q9BZ19
DIMVHLLAVRSRQRA	DNAH11	1171	Q96DT5
GHVRSLSERIMQLSL	AMOTL1	256	Q8IY63
AMNLALETAAAQRHL	DLGAP2	671	Q9P1A6
SAALHVVLRRDMSLN	DOP1A	271	Q5JWR5
SRHSRQVLLLQDSFM	AMIGO2	266	Q86SJ2
DRALNITSLQMHSLR	CA11	256	O75493
HSMAQHVARLVRVLA	DNHD1	2866	Q96M86
VIHLITAARNMAALD	CDIPT	191	O14735
SSSLLAKMRARNHLI	ERCC6	1386	Q03468
HRTLAAMLGSLAALA	OCA2	351	Q04671
SRDITLFHAMDTLQR	MTA2	226	O94776
IRRHLANATTDLMKL	GDAP1L1	181	Q96MZ0
RHLDVMDLSKNQIRS	LRRC57	131	Q8N9N7
MLQDIQRHSSVSRLA	NPAT	1246	Q14207
AAHTLMILSRAAISR	NPAT	1331	Q14207
IIDLMARTSAHFARL	ANKRD13A	381	Q8IZ07
VHNVLVSAAMRRDRF	ERCC6	676	P0DP91
HENSTLREEIAMLRL	POTEF	646	A5A3E0
AIARARHSLSDPNMR	NRBP2	266	Q9NSY0
AMTALQTLHLRSTQR	FLII	196	Q13045
LVSMSVRELNRHLRG	MAFB	216	Q9Y5Q3
VLCRSAVIDHMSRIA	LAMA3	996	Q16787
ALLMRHRALSIENSQ	LDOC1	11	O95751
AIAVERHRSVMAVQL	LPAR2	121	Q9HBW0
MAQSLRLHFAARRSN	NEDD4	1	P46934
RHESAKADLLRSQSM	KCNH7	866	Q9NS40
MAAERQRTDLETLLH	KIAA1755	946	Q5JYT7
IALSDARSMKHALRE	MAPK4	51	P31152
LQRNLSELHMTTARR	MMRN2	376	Q9H8L6
VNILSDMHLRSIRTK	FXR1	181	P51114
MATEVHNLQELRRSA	GOLGA7B	1	Q2TAP0
KAQLEASHQRALRML	FAM184B	656	Q9ULE4
FLNMKVRRTHLVSDS	HECTD2	416	Q5U5R9
QRIDLLHRMRSFSEV	DAG1	206	Q14118
RIRSLDKEHSVMLNN	CCDC178	596	Q5BJE1
AAVSAMLHAVAASRL	CCDC97	61	Q96F63
DASLRMHNLSILVRQ	CCDC88A	71	Q3V6T2
REQRLAHLVLSFLTM	IDO2	91	Q6ZQW0
GNTVIHLDQALARMR	PCM1	1511	Q15154
DLRVRCVMATLQHTA	EXOC2	581	Q96KP1
LSSARLQQMSERFLH	KXD1	51	Q9BQD3
LAMLSRRTLFTENHL	FAM83D	546	Q9H4H8
NSLHSLQSRMEDRLD	TCF12	391	Q99081
MLRSVHDVIAAARLA	DNAH12	1076	Q6ZR08
ALLNLHTDVGSVRMR	NEK8	261	Q86SG6
RMENASLLLSSLAHV	NPHS2	196	Q9NP85
LAHKLNARMADLRRS	MAT1A	156	Q00266
AHVSAQQVAMLARAR	MROH6	661	A6NGR9
ILLTVHRMNSAEGRR	OR2T35	221	Q8NGX2
FLLRQVMRHDNSSIL	PITPNM2	956	Q9BZ72
MLLHAATRQAAGIRL	DDX11	371	Q96FC9
VAMVTAVAARLAAHR	HK3	466	P52790
IRQLAIHLRNAMTTR	NOC2L	381	Q9Y3T9
IISAILRMHSAEGRQ	OR8U9	221	P0C7N5
ELEALRLSLSNMHTA	PCNT	246	O95613
RSIMRSLLEAVSFLH	PHKG2	131	P15735
NMALSKIIAVLRAHS	EXOC6	366	Q8TAG9
ANSNALLHTLLMARL	OR1F2P	151	Q96R84
LMINQHLIRTRSTAS	PPP1R3A	321	Q16821
LSLLMDQAHDSRFRL	FANCB	506	Q8NB91
TAALLAHLQRRREAM	OBSCN	216	Q5VST9
HLSLAHNRLAMATAL	LRRC32	101	Q14392
HENSTLREEIAMLRL	POTEE	646	Q6S8J3
MTSLFAQEIRLSKRH	C3orf14	1	Q9HBI5
LMNALERSHIESLRN	EFCAB5	961	A4FU69
MSSNIISRNHVTRLL	GSAP	771	A4D1B5
ASMILHDIARARENI	EEF1DP3	41	Q658K8
RHMLFTIKDNTLRAT	CEFIP	851	Q711Q0
RAQEQSDHALMLREL	GCC1	236	Q96CN9
TKRAIHTLAVMNDRL	KLHL14	506	Q9P2G3
ENSSHRRAILMELER	BFAR	231	Q9NZS9
HRRIDMSLAELQSKQ	BCLAF3	521	A2AJT9
ARLASSMALAEQARQ	GLYCTK	26	Q8IVS8
ARKHARFVLSLNQTM	CCDC175	171	P0C221
NRTMRLVFEISHLRT	DNAH17	2236	Q9UFH2
HLAFRSVSMAIQRIS	DNAH17	2611	Q9UFH2
NRAITHLMRSAKERV	EIF2AK1	121	Q9BQI3
VARNRFAVLDRMHSL	COPA	421	P53621
IERMNSIHRDLRAAN	BLK	351	P51451
ARRLRNHMAVAFVLS	COX6C	16	P09669
ALSVLLRSIHSAMER	GALNT18	166	Q6P9A2
EEMRAAHQSSLLRLR	CEP350	1691	Q5VT06
LAARAIHNIFRMTES	APPL2	521	Q8NEU8
AMLDHSNLIREVNRR	CCDC85A	66	Q96PX6
DDHLRLVRNISTGMA	C3orf33	31	Q6P1S2
TLERSAIAREHMGQL	EIF4G1	1286	Q04637
LRRANLTSMLIQRVH	MAN2A2	301	P49641
SRLEGLQSENHRLRM	GABBR2	786	O75899
SLVSLFQALRHDLMR	FAM180A	151	Q6UWF9
RMGTSLLFQLSVHER	KANSL3	16	Q9P2N6
RSINLTLDRSMQHFR	CNTNAP2	286	Q9UHC6
AVSMKLHRVREALAL	DCST2	311	Q5T1A1
QLMREQRARHLSNDS	CACNA1H	431	O95180
MLERHITQAQARAIA	DLEC1	151	Q9Y238
RDTTQLLASEMVHLR	CAMSAP2	751	Q08AD1
SIHRLMEAFILRLQT	CTU2	341	Q2VPK5
RTGNHVLSMARLARD	CPNE5	531	Q9HCH3
IILSTARMNRVLSFH	D2HGDH	146	Q8N465
MQSRVHVAALLRKLS	FOCAD	1156	Q5VW36
ARVASRLIDMSRHQG	FTCD	66	O95954
DSNQAAMVLIRLSHL	TBRG4	96	Q969Z0
DLQSMVTSLRTLRHL	LRRC43	236	Q8N309
EMALRRLSHDVSGAL	MAP3K1	581	Q13233
AEAHARLMFRDTVTL	MCM9	576	Q9NXL9
QSLVNMTSRLRHLAE	NAV1	1116	Q8NEY1
IISAILRMHSAEGRQ	OR8U1	221	Q8NH10
LMSLLAVSRRAQKHA	RTTN	1866	Q86VV8
MAAAAASHLNLDALR	TRIM32	1	Q13049
LTVRTSRRHQAMAIA	TRMT2A	316	Q8IZ69
VNVRDRTMADLHTAR	TAX1BP1	381	Q86VP1
FLRSMDVIAEQRRTH	TMEM185A	196	Q8NFB2
LSRSLQEHMGSRLLD	TOGARAM2	956	Q6ZUX3
TVNLDHSIRRRMGLI	NKPD1	521	Q17RQ9
SARSVMLDRAENLLH	POFUT2	211	Q9Y2G5
SLRLLEMAEAQNRHT	ODAD3	186	A5D8V7
TQHRRQEAMAALRFL	SLC2A8	211	Q9NY64
IRTLNADLMTLSHRE	LAMA1	231	P25391
GIRAMDLSHDQRTLI	NBEA	2906	Q8NFP9
RLHSMSQETIHRNLA	PRDM11	266	Q9NQV5
REILSAAEHFSMIRA	MEX3C	291	Q5U5Q3
MLNRVRSAVAHLVSS	PPM1J	1	Q5JR12
ELDTNQHRTHAMRLL	STRIP1	116	Q5VSL9
MIADTVRTLRHCRTN	RAPGEF5	526	Q92565
IRQIADHSLMTSKRD	SHOC1	1011	Q5VXU9
LHRRVAAMREAGTAL	SIKE1	36	Q9BRV8
AVGAALVMLRRHLNQ	SHPK	461	Q9UHJ6
HLRLSANDAEDSLRM	PGAP1	801	Q75T13
HENSTLREEIAMLRL	POTEI	646	P0CG38
LAAERIHAERMASLT	RERE	1396	Q9P2R6
ARERTLAMQAGNLHL	TEX45	101	Q8NA69
DISMILAEAIRRTHN	PRPS1L1	291	P21108
QALSETMKQARHRLA	CCDC15	171	Q0P6D6
ATLHMAVRDLVRSVF	CHST6	86	Q9GZX3
AVDTMSLRLLTHQRA	NCAPH2	576	Q6IBW4
ELLHTLNFDAVRRRM	ATP11C	536	Q8NB49
DSIHARRTMQVALGL	TGFBRAP1	776	Q8WUH2
VTASAQHALRMLAFR	ZFR2	876	Q9UPR6
ATHLARLEESCRAAM	RIBC1	196	Q8N443
TNAQARAMLRRHSLI	MPDZ	1066	O75970
LGVHRARILTAAREM	SARM1	531	Q6SZW1
LSTASAMQRHIRLVH	SLC2A4RG	211	Q9NR83
ALMDRDLVHRQTASA	SF3B1	1176	O75533
ASETIRTRLMELHRQ	SPTAN1	116	Q13813
DISMILAEAIRRTHN	PRPS2	291	P11908
TIMDRSIILRHLLNS	UBE4B	1251	O95155
MSAHRVSGALARVLE	YDJC	216	A8MPS7
MHLTDSVVRRQLFLD	NUP188	1121	Q5SRE5
MEDSNRNSIVELRHL	SCLT1	566	Q96NL6
RNASIHTLLDALERM	TNFRSF10A	421	O00220
TRAALMSRFILNHLV	PLPP6	216	Q8IY26
QRRLDLVHTAALMLD	SNRNP200	951	O75643
DTIRVFLHQIAAAMR	ULK2	106	Q8IYT8
SSVHKNVARSLLMER	TTC38	431	Q5R3I4
TLTIHLMRFSIRNSQ	USP41	251	Q3LFD5
ILRFLHRNRLSSAVM	ZZEF1	186	O43149
RAFRIASELAQHIRM	ZNF648	511	Q5T619
DISMILAEAIRRTHN	PRPS1	291	P60891
EISFTLMLTERRNHA	SPHK1	46	Q9NYA1
TLTIHLMRFSIRNSQ	USP18	251	Q9UMW8
LMNLEVRELRHSRTG	TSPY26P	221	Q9H489
QALTALEMLSRRHSK	TRIP12	541	Q14669
LEMLSRRHSKAILQA	TRIP12	546	Q14669
LQVLQDMASRLRIHS	TKTL1	21	P51854
RKHMRERLAALAAQA	TRIM3	271	O75382
REHDIRVSLRMASVQ	VPS13D	1961	Q5THJ4
HRVAGLQMTLTELRA	KDM5C	841	P41229
HRLRMADILSQSETL	SLC4A1AP	51	Q9BWU0
HLVRIALQEDTNRMS	MYO9A	2191	B2RTY4
AMLSQSLDLSDRHRA	MYO9B	1326	Q13459
SHRLDAVNTLLAMAE	MYOF	651	Q9NZM1
RSRSLSQIHEAAVRM	MYOF	726	Q9NZM1
SLHFAQVRTERMLLD	NAA25	606	Q14CX7
SHHRVAMARLALQTS	NMNAT3	61	Q96T66