Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	magnesium ion binding	ENOSF1 RAP2A MAST2 PGM5 MSH6 MAST4 GEN1 MAST3	1.32e-04	247	121	8	GO:0000287
GeneOntologyMolecularFunction	very-low-density lipoprotein particle receptor binding	LRPAP1 PCSK9	2.17e-04	4	121	2	GO:0070326
Domain	DUF1908	MAST2 MAST4 MAST3	9.54e-07	4	117	3	PF08926
Domain	MA_Ser/Thr_Kinase_dom	MAST2 MAST4 MAST3	9.54e-07	4	117	3	IPR015022
Domain	MAST_pre-PK_dom	MAST2 MAST4 MAST3	9.54e-07	4	117	3	IPR023142
Domain	-	MAST2 MAST4 MAST3	9.54e-07	4	117	3	1.20.1480.20
Domain	Laminin_G	FAT4 COL12A1 FAT3 NRXN3	4.78e-04	58	117	4	IPR001791
Domain	-	BRIP1 RAP2A RAP2B MYO7B AK9 BTAF1 ARHGAP35 DICER1 MSH6 DNAH12 UCK2 DSEL RAP2C	8.02e-04	746	117	13	3.40.50.300
Domain	HEAT_REPEAT	PPP4R1 COPG2 BTAF1 PPP2R1B	9.75e-04	70	117	4	PS50077
Domain	Atg8	MAP1LC3B2 MAP1LC3B	1.06e-03	8	117	2	PF02991
Domain	Atg8-like	MAP1LC3B2 MAP1LC3B	1.06e-03	8	117	2	IPR004241
Domain	RAS	RAP2A RAP2B RAP2C	1.35e-03	35	117	3	PS51421
Domain	Small_GTPase_Ras	RAP2A RAP2B RAP2C	1.59e-03	37	117	3	IPR020849
Domain	LAM_G_DOMAIN	FAT4 FAT3 NRXN3	1.72e-03	38	117	3	PS50025
Domain	Laminin_G_2	FAT4 FAT3 NRXN3	2.00e-03	40	117	3	PF02210
Domain	Kinase-like_dom	TEX14 ARHGAP35 TEK MAST2 AATK MAST4 MAPK11 MAP2K5 WNK3 MAST3	2.17e-03	542	117	10	IPR011009
Domain	P-loop_NTPase	BRIP1 RAP2A RAP2B MYO7B AK9 BTAF1 ARHGAP35 DICER1 MSH6 DNAH12 UCK2 DSEL RAP2C	2.52e-03	848	117	13	IPR027417
Domain	LamG	FAT4 FAT3 NRXN3	2.63e-03	44	117	3	SM00282
Domain	HTH_Tnp_Tc5	DCHS2 TIGD1	2.90e-03	13	117	2	PF03221
Domain	-	FAT4 COL12A1 FAT3 NRXN3	3.00e-03	95	117	4	2.60.120.200
Domain	HEAT	PPP4R1 BTAF1 PPP2R1B	3.38e-03	48	117	3	PF02985
Domain	fn3	COL12A1 FNDC3A TEK MYBPC1 MYBPC3	3.54e-03	162	117	5	PF00041
Domain	ASX_HYDROXYL	FAT4 FAT3 F9 NRXN3	3.61e-03	100	117	4	PS00010
Domain	Prot_kinase_dom	TEX14 TEK MAST2 AATK MAST4 MAPK11 MAP2K5 WNK3 MAST3	3.66e-03	489	117	9	IPR000719
Domain	PROTEIN_KINASE_DOM	TEX14 TEK MAST2 AATK MAST4 MAPK11 MAP2K5 WNK3 MAST3	3.85e-03	493	117	9	PS50011
Domain	-	GBF1 PSD3	3.87e-03	15	117	2	1.10.1000.11
Domain	Sec7	GBF1 PSD3	3.87e-03	15	117	2	PF01369
Domain	Sec7_alpha_orthog	GBF1 PSD3	3.87e-03	15	117	2	IPR023394
Domain	SEC7	GBF1 PSD3	4.41e-03	16	117	2	PS50190
Domain	Sec7	GBF1 PSD3	4.41e-03	16	117	2	SM00222
Domain	Sec7_dom	GBF1 PSD3	4.41e-03	16	117	2	IPR000904
Domain	EGF-type_Asp/Asn_hydroxyl_site	FAT4 FAT3 F9 NRXN3	4.45e-03	106	117	4	IPR000152
Domain	HEAT_type_2	PPP4R1 PPP2R1B	4.98e-03	17	117	2	IPR021133
Domain	AGC-kinase_C	MAST2 MAST4 MAST3	5.22e-03	56	117	3	IPR000961
Domain	AGC_KINASE_CTER	MAST2 MAST4 MAST3	5.22e-03	56	117	3	PS51285
Domain	S_TK_X	MAST2 MAST4 MAST3	5.22e-03	56	117	3	SM00133
Domain	HEAT	PPP4R1 BTAF1 PPP2R1B	5.75e-03	58	117	3	IPR000357
Domain	FN3	COL12A1 FNDC3A TEK MYBPC1 MYBPC3	6.20e-03	185	117	5	SM00060
Pubmed	Rap2, but not Rap1 GTPase is expressed in human red blood cells and is involved in vesiculation.	RAP2A RAP2B RAP2C	1.68e-07	4	122	3	16540189
Pubmed	Ubiquitylation by Rab40b/Cul5 regulates Rap2 localization and activity during cell migration.	RAP2A RAP2B RAP2C	4.19e-07	5	122	3	35293963
Pubmed	CaV2.2 channel cell surface expression is regulated by the light chain 1 (LC1) of the microtubule-associated protein B (MAP1B) via UBE2L3-mediated ubiquitination and degradation.	MAP1B MAP1LC3B2 MAP1LC3B	4.19e-07	5	122	3	24566975
Pubmed	Comprehensive Interactome Mapping of the DNA Repair Scaffold SLX4 Using Proximity Labeling and Affinity Purification.	BRIP1 ZFC3H1 REV3L YEATS2 MSH6 UBN1 PPIL2 IK	1.25e-06	222	122	8	37071664
Pubmed	Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.	GBF1 PSD3 FNDC3A ARHGAP35 DICER1 KMT2C AATK DOP1B	1.39e-06	225	122	8	12168954
Pubmed	Gene network analysis in a pediatric cohort identifies novel lung function genes.	BRIP1 PSD3 MICAL3 MYBPC1	1.45e-06	24	122	4	24023788
Pubmed	Expression of mouse dchs1, fjx1, and fat-j suggests conservation of the planar cell polarity pathway identified in Drosophila.	DCHS2 FAT4 FAT3	1.46e-06	7	122	3	16059920
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	RAP2B GBF1 RHBDF1 PCNX3 UBE3B HECTD4 BTAF1 REV3L ARHGAP35 MAST2 KMT2C TNRC18 AATK UBN1 KLHL21 MICAL3	1.70e-06	1105	122	16	35748872
Pubmed	Perinatal lethality of microtubule-associated protein 1B-deficient mice expressing alternative isoforms of the protein at low levels.	MAP1B MAP1LC3B2 MAP1LC3B	2.33e-06	8	122	3	11085878
Pubmed	Synaptic Vesicle Precursors and Lysosomes Are Transported by Different Mechanisms in the Axon of Mammalian Neurons.	MAP1LC3B2 SYP MAP1LC3B	3.48e-06	9	122	3	32553155
Pubmed	JAM-A associates with ZO-2, afadin, and PDZ-GEF1 to activate Rap2c and regulate epithelial barrier function.	RAP2B F11R RAP2C	4.96e-06	10	122	3	23885123
Pubmed	Cathepsin D in pancreatic acinar cells is implicated in cathepsin B and L degradation, but not in autophagic activity.	MAP1LC3B2 MAP1LC3B CTSV	6.81e-06	11	122	3	26682926
Pubmed	A novel missense mutation in the myosin binding protein-C gene is responsible for hypertrophic cardiomyopathy with left ventricular dysfunction and dilation in elderly patients.	MYBPC1 MYBPC3	1.22e-05	2	122	2	12628722
Pubmed	Nutrient starvation affects expression of LC3 family at the feto-maternal interface during murine placentation.	MAP1LC3B2 MAP1LC3B	1.22e-05	2	122	2	25421500
Pubmed	Autophagic protein LC3B confers resistance against hypoxia-induced pulmonary hypertension.	MAP1LC3B2 MAP1LC3B	1.22e-05	2	122	2	20889906
Pubmed	Microtubule-associated protein 1B is involved in the initial stages of axonogenesis in peripheral nervous system cultured neurons.	MAP1LC3B2 MAP1LC3B	1.22e-05	2	122	2	12088839
Pubmed	Lc3 over-expression improves survival and attenuates lung injury through increasing autophagosomal clearance in septic mice.	MAP1LC3B2 MAP1LC3B	1.22e-05	2	122	2	22968077
Pubmed	Whole exome sequencing of breast cancer (TNBC) cases from India: association of MSH6 and BRIP1 variants with TNBC risk and oxidative DNA damage.	BRIP1 MSH6	1.22e-05	2	122	2	30136158
Pubmed	Cross-talk between miR-471-5p and autophagy component proteins regulates LC3-associated phagocytosis (LAP) of apoptotic germ cells.	MAP1LC3B2 MAP1LC3B	1.22e-05	2	122	2	28928467
Pubmed	Identification and biochemical characterization of Rap2C, a new member of the Rap family of small GTP-binding proteins.	RAP2B RAP2C	1.22e-05	2	122	2	16213650
Pubmed	Transcriptomic Changes Predict Metabolic Alterations in LC3 Associated Phagocytosis in Aged Mice.	MAP1LC3B2 MAP1LC3B	1.22e-05	2	122	2	37047689
Pubmed	Cell-Penetrating Nanoparticles Activate the Inflammasome to Enhance Antibody Production by Targeting Microtubule-Associated Protein 1-Light Chain 3 for Degradation.	MAP1LC3B2 MAP1LC3B	1.22e-05	2	122	2	32057231
Pubmed	Prenyl group identification of rap2 proteins: a ras superfamily member other than ras that is farnesylated.	RAP2A RAP2B	1.22e-05	2	122	2	8424780
Pubmed	Andrographolide alleviates imiquimod-induced psoriasis in mice via inducing autophagic proteolysis of MyD88.	MAP1LC3B2 MAP1LC3B	1.22e-05	2	122	2	27265145
Pubmed	Slowly progressive behavioral frontotemporal dementia syndrome in a family co-segregating the C9orf72 expansion and a Synaptophysin mutation.	SYP C9orf72	1.22e-05	2	122	2	34310040
Pubmed	Individual Atg8 paralogs and a bacterial metabolite sequentially promote hierarchical CASM-xenophagy induction and transition.	MAP1LC3B2 MAP1LC3B	1.22e-05	2	122	2	38656870
Pubmed	Identification of new human cadherin genes using a combination of protein motif search and gene finding methods.	DCHS2 FAT4	1.22e-05	2	122	2	15003449
Pubmed	[Preparation of an autophagy-targeted antituberculosis DNA vaccine encoding LpqH fused with LC3].	MAP1LC3B2 MAP1LC3B	1.22e-05	2	122	2	24909277
Pubmed	Microtubule-Associated Protein 1 Light Chain 3B, (LC3B) Is Necessary to Maintain Lipid-Mediated Homeostasis in the Retinal Pigment Epithelium.	MAP1LC3B2 MAP1LC3B	1.22e-05	2	122	2	30349463
Pubmed	Susceptibility of microtubule-associated protein 1 light chain 3β (MAP1LC3B/LC3B) knockout mice to lung injury and fibrosis.	MAP1LC3B2 MAP1LC3B	1.22e-05	2	122	2	31431059
Pubmed	Peroxisome turnover and diurnal modulation of antioxidant activity in retinal pigment epithelia utilizes microtubule-associated protein 1 light chain 3B (LC3B).	MAP1LC3B2 MAP1LC3B	1.22e-05	2	122	2	31577510
Pubmed	LC3 conjugation system in mammalian autophagy.	MAP1LC3B2 MAP1LC3B	1.22e-05	2	122	2	15325588
Pubmed	LC3B is lipidated to large lipid droplets during prolonged starvation for noncanonical autophagy.	MAP1LC3B2 MAP1LC3B	1.22e-05	2	122	2	37315562
Pubmed	Characterization of the interactome of the human MutL homologues MLH1, PMS1, and PMS2.	BRIP1 PSD3 COPG2 REV3L MSH6	1.44e-05	87	122	5	17148452
Pubmed	Rap2A links intestinal cell polarity to brush border formation.	RAP2A RAP2B RAP2C	1.86e-05	15	122	3	22797597
Pubmed	Proteome-scale mapping of binding sites in the unstructured regions of the human proteome.	GBF1 INPP5K NDFIP2 TEX14 TNRC18 AATK MIA2 UBN1 MAP1LC3B	2.21e-05	430	122	9	35044719
Pubmed	Altered heparan sulfate metabolism during development triggers dopamine-dependent autistic-behaviours in models of lysosomal storage disorders.	MAP1LC3B2 SYP MAP1LC3B	2.28e-05	16	122	3	34108486
Pubmed	Requirement of FAT and DCHS protocadherins during hypothalamic-pituitary development.	DCHS2 FAT4 FAT3	3.31e-05	18	122	3	33108146
Pubmed	Signaling and regulation of the platelet glycoprotein Ib-IX-V complex.	F5 F9	3.65e-05	3	122	2	17414217
Pubmed	Mesenchymal Stromal Cells Deficient in Autophagy Proteins Are Susceptible to Oxidative Injury and Mitochondrial Dysfunction.	MAP1LC3B2 MAP1LC3B	3.65e-05	3	122	2	27636016
Pubmed	Classical autophagy proteins LC3B and ATG4B facilitate melanosome movement on cytoskeletal tracks.	MAP1LC3B2 MAP1LC3B	3.65e-05	3	122	2	28598240
Pubmed	Factor V Leiden improves in vivo hemostasis in murine hemophilia models.	F5 F9	3.65e-05	3	122	2	16359510
Pubmed	HIV protease inhibitor-induced cardiac dysfunction and fibrosis is mediated by platelet-derived TGF-β1 and can be suppressed by exogenous carbon monoxide.	MAP1LC3B2 MAP1LC3B	3.65e-05	3	122	2	29088262
Pubmed	Epac, Rap and Rab3 act in concert to mobilize calcium from sperm's acrosome during exocytosis.	RAB3GAP1 LRPAP1	3.65e-05	3	122	2	25159528
Pubmed	Autophagy is required and protects against apoptosis during myoblast differentiation.	MAP1LC3B2 MAP1LC3B	3.65e-05	3	122	2	24865278
Pubmed	Developmental expression of LC3alpha and beta: absence of fibronectin or autophagy phenotype in LC3beta knockout mice.	MAP1LC3B2 MAP1LC3B	3.65e-05	3	122	2	18069693
Pubmed	BAT3 modulates p300-dependent acetylation of p53 and autophagy-related protein 7 (ATG7) during autophagy.	MAP1LC3B2 MAP1LC3B	3.65e-05	3	122	2	24591579
Pubmed	The crystal structure of mouse LC3B in complex with the FYCO1 LIR reveals the importance of the flanking region of the LIR motif.	MAP1LC3B2 MAP1LC3B	3.65e-05	3	122	2	28291748
Pubmed	Autophagy plays an essential role in cigarette smoke-induced expression of MUC5AC in airway epithelium.	MAP1LC3B2 MAP1LC3B	3.65e-05	3	122	2	27036871
Pubmed	Microtubule-Associated Protein 1 Light Chain 3 (LC3) Isoforms in RPE and Retina.	MAP1LC3B2 MAP1LC3B	3.65e-05	3	122	2	29721994
Pubmed	Regulation of autophagic flux by dynein-mediated autophagosomes trafficking in mouse coronary arterial myocytes.	MAP1LC3B2 MAP1LC3B	3.65e-05	3	122	2	24095928
Pubmed	Human cDNAs rap1 and rap2 homologous to the Drosophila gene Dras3 encode proteins closely related to ras in the 'effector' region.	RAP2A RAP2B	3.65e-05	3	122	2	3045729
Pubmed	Autophagy proteins are modulated in the liver and hypothalamus of the offspring of mice with diet-induced obesity.	MAP1LC3B2 MAP1LC3B	3.65e-05	3	122	2	27180121
Pubmed	ATG7 is dispensable for LC3-PE conjugation in thioglycolate-elicited mouse peritoneal macrophages.	MAP1LC3B2 MAP1LC3B	3.65e-05	3	122	2	33459130
Pubmed	BNIP3-dependent mitophagy promotes cytosolic localization of LC3B and metabolic homeostasis in the liver.	MAP1LC3B2 MAP1LC3B	3.65e-05	3	122	2	33459136
Pubmed	Chromatin remodeling enzyme Snf2h regulates embryonic lens differentiation and denucleation.	CDKN1C MAP1LC3B2 MAP1LC3B	3.92e-05	19	122	3	27246713
Pubmed	Rap2 function requires palmitoylation and recycling endosome localization.	RAP2A RAP2B RAP2C	5.35e-05	21	122	3	19061864
Pubmed	E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins.	FAT4 REV3L NDUFS3 CCN4 MSH6 KMT2C KCNJ9 PKHD1 SNX31 ALB DOP1B	5.92e-05	736	122	11	29676528
Pubmed	Dicer1 activity in the stromal compartment regulates nephron differentiation and vascular patterning during mammalian kidney organogenesis.	CDKN1C DICER1 CCN4	6.18e-05	22	122	3	25651362
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	GBF1 ZFC3H1 ARHGAP35 RAB3GAP1 TNRC18 DNAH17 MICAL3 FAM135A MAST3	6.36e-05	493	122	9	15368895
Pubmed	p62 aggregates mediated Caspase 8 activation is responsible for progression of ovarian cancer.	MAP1LC3B2 MAP1LC3B	7.29e-05	4	122	2	30941888
Pubmed	The Hedgehog signalling pathway regulates autophagy.	MAP1LC3B2 MAP1LC3B	7.29e-05	4	122	2	23149744
Pubmed	MAP1LC3B overexpression protects against Hermansky-Pudlak syndrome type-1-induced defective autophagy in vitro.	MAP1LC3B2 MAP1LC3B	7.29e-05	4	122	2	26719147
Pubmed	The Contribution of Melanoregulin to Microtubule-Associated Protein 1 Light Chain 3 (LC3) Associated Phagocytosis in Retinal Pigment Epithelium.	MAP1LC3B2 MAP1LC3B	7.29e-05	4	122	2	25301234
Pubmed	Binding of PTEN to specific PDZ domains contributes to PTEN protein stability and phosphorylation by microtubule-associated serine/threonine kinases.	MAST2 MAST3	7.29e-05	4	122	2	15951562
Pubmed	The Atg8 conjugation system is indispensable for proper development of autophagic isolation membranes in mice.	MAP1LC3B2 MAP1LC3B	7.29e-05	4	122	2	18768753
Pubmed	Hepatocellular carcinoma-related cyclin D1 is selectively regulated by autophagy degradation system.	MAP1LC3B2 MAP1LC3B	7.29e-05	4	122	2	29328502
Pubmed	Perturbation of PI3K/Akt signaling affected autophagy modulation in dystrophin-deficient myoblasts.	MAP1LC3B2 MAP1LC3B	7.29e-05	4	122	2	34706731
Pubmed	Acetylation modulates LC3 stability and cargo recognition.	MAP1LC3B2 MAP1LC3B	7.29e-05	4	122	2	30633346
Pubmed	Hyperoxia-induced LC3B interacts with the Fas apoptotic pathway in epithelial cell death.	MAP1LC3B2 MAP1LC3B	7.29e-05	4	122	2	22095627
Pubmed	Immunity-related GTPase induces lipophagy to prevent excess hepatic lipid accumulation.	MAP1LC3B2 MAP1LC3B	7.29e-05	4	122	2	32376415
Pubmed	Autophagy mediates tolerance to Staphylococcus aureus alpha-toxin.	MAP1LC3B2 MAP1LC3B	7.29e-05	4	122	2	25816775
Pubmed	Identification and characterization of potential effector molecules of the Ras-related GTPase Rap2.	RAP2A RAP2B	7.29e-05	4	122	2	10085114
Pubmed	STING induces LC3B lipidation onto single-membrane vesicles via the V-ATPase and ATG16L1-WD40 domain.	MAP1LC3B2 MAP1LC3B	7.29e-05	4	122	2	33201170
Pubmed	PARG1, a protein-tyrosine phosphatase-associated RhoGAP, as a putative Rap2 effector.	RAP2A RUNDC3A	7.29e-05	4	122	2	15752761
Pubmed	Differential roles of Ras and Rap1 in growth factor-dependent activation of phospholipase C epsilon.	RAP2A RAP2B	7.29e-05	4	122	2	12444546
Pubmed	Leucine-rich repeat containing 4 act as an autophagy inhibitor that restores sensitivity of glioblastoma to temozolomide.	MAP1LC3B2 MAP1LC3B	7.29e-05	4	122	2	32372061
Pubmed	Deficiency of autophagy protein Map1-LC3b mediates IL-17-dependent lung pathology during respiratory viral infection via ER stress-associated IL-1.	MAP1LC3B2 MAP1LC3B	7.29e-05	4	122	2	25669150
Pubmed	Aging is associated with hypermethylation of autophagy genes in macrophages.	MAP1LC3B2 MAP1LC3B	7.29e-05	4	122	2	26909551
Pubmed	Modulation of autophagy influences development and apoptosis in mouse embryos developing in vitro.	MAP1LC3B2 MAP1LC3B	7.29e-05	4	122	2	21681844
Pubmed	Histone deacetylase 6-mediated selective autophagy regulates COPD-associated cilia dysfunction.	MAP1LC3B2 MAP1LC3B	7.29e-05	4	122	2	24200693
Pubmed	Atg8 transfer from Atg7 to Atg3: a distinctive E1-E2 architecture and mechanism in the autophagy pathway.	MAP1LC3B2 MAP1LC3B	7.29e-05	4	122	2	22055190
Pubmed	Autophagic compartments gain access to the MHC class II compartments in thymic epithelium.	MAP1LC3B2 MAP1LC3B	7.29e-05	4	122	2	19915056
Pubmed	Autophagy exacerbates electrical remodeling in atrial fibrillation by ubiquitin-dependent degradation of L-type calcium channel.	MAP1LC3B2 MAP1LC3B	7.29e-05	4	122	2	30158642
Pubmed	WD40 repeat and FYVE domain containing 3 is essential for cardiac development.	CDKN1C MAP1LC3B2 MAP1LC3B	9.15e-05	25	122	3	30428088
Pubmed	Mab21l2 is essential for embryonic heart and liver development.	CDKN1C TEK ALB	9.15e-05	25	122	3	22412967
Pubmed	Differential expression of sex-linked and autosomal germ-cell-specific genes during spermatogenesis in the mouse.	TEX14 TAF7L	1.21e-04	5	122	2	16118233
Pubmed	Autophagy proteins are required for club cell structure and function in airways.	MAP1LC3B2 MAP1LC3B	1.21e-04	5	122	2	31116580
Pubmed	Isoform transitions of the myosin binding protein C family in developing human and mouse muscles: lack of isoform transcomplementation in cardiac muscle.	MYBPC1 MYBPC3	1.21e-04	5	122	2	9440711
Pubmed	Cytosolic clearance of replication-deficient mutants reveals Francisella tularensis interactions with the autophagic pathway.	MAP1LC3B2 MAP1LC3B	1.21e-04	5	122	2	22863802
Pubmed	Autophagy proteins regulate innate immune responses by inhibiting the release of mitochondrial DNA mediated by the NALP3 inflammasome.	MAP1LC3B2 MAP1LC3B	1.21e-04	5	122	2	21151103
Pubmed	Angiopoietin-1 requires p190 RhoGAP to protect against vascular leakage in vivo.	ARHGAP35 TEK	1.21e-04	5	122	2	17562701
Pubmed	NEDD4-family E3 ligase dysfunction due to PKHD1/Pkhd1 defects suggests a mechanistic model for ARPKD pathobiology.	NDFIP2 PKHD1	1.21e-04	5	122	2	28798345
Pubmed	Identification of a specific effector of the small GTP-binding protein Rap2.	RAP2A RUNDC3A	1.21e-04	5	122	2	9523700
Pubmed	Selective degradation of PU.1 during autophagy represses the differentiation and antitumour activity of TH9 cells.	MAP1LC3B2 MAP1LC3B	1.21e-04	5	122	2	28916785
Pubmed	Autophagy prior to chondrocyte cell death during the degeneration of Meckel's cartilage.	MAP1LC3B2 MAP1LC3B	1.21e-04	5	122	2	22371349
Pubmed	Differential expression of C-protein isoforms in developing and degenerating mouse striated muscles.	MYBPC1 MYBPC3	1.21e-04	5	122	2	10024132
Pubmed	In Vivo Evidence for Lysosome Depletion and Impaired Autophagic Clearance in Hereditary Spastic Paraplegia Type SPG11.	MAP1LC3B2 MAP1LC3B	1.21e-04	5	122	2	26284655
Pubmed	The fructose-2,6-bisphosphatase TIGAR suppresses NF-κB signaling by directly inhibiting the linear ubiquitin assembly complex LUBAC.	RNF31 NFKBIA	1.21e-04	5	122	2	29650758
Pubmed	Autophagy-related gene Atg5 is essential for astrocyte differentiation in the developing mouse cortex.	MAP1LC3B2 MAP1LC3B	1.21e-04	5	122	2	25227738
Cytoband	6q12-q13	COL12A1 RIMS1	6.97e-05	5	122	2	6q12-q13
GeneFamily	Cadherin related	DCHS2 FAT4 FAT3	5.63e-05	17	81	3	24
GeneFamily	RAS type GTPase family	RAP2A RAP2B RAP2C	3.56e-04	31	81	3	389
GeneFamily	Fibronectin type III domain containing\|I-set domain containing\|Myosin binding proteins	MYBPC1 MYBPC3	5.45e-04	8	81	2	658
GeneFamily	Fibronectin type III domain containing	COL12A1 FNDC3A TEK MYBPC1 MYBPC3	7.60e-04	160	81	5	555
GeneFamily	Dyneins, axonemal	DNAH12 DNAH17	2.58e-03	17	81	2	536
ToppCell	COVID-19-kidney-Fibroblast-2\|COVID-19 / Disease (COVID-19 only), tissue and cell type	COL12A1 MAP1B REV3L CCN4 SRPX2 CYP7B1 GFPT2	1.07e-06	195	121	7	3d62ce1c696f47d4d7eb0c5bb0eec2c24b122bb2
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	MAP1B COPG2 RTN1 NRXN3 CSRNP3 SYP RIMS1	1.11e-06	196	121	7	676c56b44ac29f7baecb62f49bb8597cc74c0a88
ToppCell	Somatosensory_Cortex_(S1)-Neuronal\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	MAP1B COPG2 RTN1 NRXN3 CSRNP3 SYP RIMS1	1.19e-06	198	121	7	c01091ef18e096d792ea2a7a715764a5b215355f
ToppCell	primary_auditory_cortex_(A1C)-Neuronal\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	MAP1B COPG2 RTN1 NRXN3 CSRNP3 SYP RIMS1	1.19e-06	198	121	7	6d18b45eda4014759e6dd282d78ffd28df8a6044
ToppCell	Primary_Motor_Cortex_(M1)-Neuronal\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	MAP1B COPG2 RTN1 NRXN3 CSRNP3 SYP RIMS1	1.19e-06	198	121	7	4ca5ff320905ab4ff60ed90a5522227c782142a6
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Neuronal\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	MAP1B COPG2 RTN1 NRXN3 CSRNP3 SYP RIMS1	1.19e-06	198	121	7	0ff30edfd3c133a42e8cb96e1631a1143215f808
ToppCell	Neuronal\|World / cells hierarchy compared to all cells using T-Statistic	MAP1B COPG2 RTN1 NRXN3 CSRNP3 SYP RIMS1	1.27e-06	200	121	7	48d801219bc771d6c7e151dc88ca4c179988de85
ToppCell	Brain_organoid-organoid_Tanaka_cellReport-2m-Neuronal-Interneuron\|2m / Sample Type, Dataset, Time_group, and Cell type.	RTN1 RUNDC3A NRXN3 CSRNP3 SYP NUP93 DSEL	1.27e-06	200	121	7	08bee924a2654e05df3b39e8a51f93c8b3472175
ToppCell	Brain_organoid-organoid_Tanaka_cellReport-1m-Neuronal-Interneuron\|1m / Sample Type, Dataset, Time_group, and Cell type.	DCHS2 MAP1B RTN1 BRWD3 RUNDC3A NRXN3 CSRNP3	1.27e-06	200	121	7	fc839e9c33ea1d4ee0f42f21fd32a54e7cbe1f5a
ToppCell	facs-Marrow-B-cells-24m-Lymphocytic-precursor_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL12A1 WDR64 MYO7B FAT3 AADACL2 PKHD1	5.05e-06	160	121	6	c381ec6be8cf887861cc18f831a20db42f953fe1
ToppCell	facs-Marrow-B-cells-24m-Lymphocytic-pre_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL12A1 WDR64 MYO7B FAT3 AADACL2 PKHD1	5.05e-06	160	121	6	25c8f3d2a6d14ff0ca0b965fce89d3ff22f40585
ToppCell	facs-Heart-LV-3m-Endothelial-endothelial_cell_of_endocardium\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LBP GCNT2 DICER1 PGM5 NRXN3 GEN1	7.64e-06	172	121	6	f2c17c49b375b28ad47dc6cabda62f1c238023dd
ToppCell	facs-Heart-LV-3m-Endothelial-endocardial_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LBP GCNT2 DICER1 PGM5 NRXN3 GEN1	7.64e-06	172	121	6	6ab4f01098dddb789df298ddf97b3c384405ee6c
ToppCell	3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.0.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CATSPERE CFAP300 AK9 ZBBX DNAH12 IK	1.12e-05	184	121	6	2df903924df9cb71039159416bcbe6a6614e21fe
ToppCell	facs-Brain_Non-Myeloid-Hippocampus-24m-Neuronal-neuron\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MAP1B RTN1 DLGAP3 SRPX2 NRXN3 SYP	1.23e-05	187	121	6	e04a84989d624378141042768383b9c846901f2d
ToppCell	facs-Brain_Non-Myeloid-Hippocampus-24m-Neuronal-nan\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MAP1B RTN1 DLGAP3 SRPX2 NRXN3 SYP	1.23e-05	187	121	6	24cc03c748e15f7ef0e6509ca5a6ca583fb9c573
ToppCell	facs-Brain_Non-Myeloid-Hippocampus-24m-Neuronal\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MAP1B RTN1 DLGAP3 SRPX2 NRXN3 SYP	1.23e-05	187	121	6	2f153b203fe79f206319603cf94d3a03ab49a05d
ToppCell	RV-15._Ventricular_Cardiomyocyte_III\|World / Chamber and Cluster_Paper	PSD3 FNDC3A MAST2 MAST4 MICAL3 MYBPC3	1.31e-05	189	121	6	0a82931b5f6c0a6427ca3edd5e2235ac49099d40
ToppCell	RV-15._Ventricular_Cardiomyocyte_III\|RV / Chamber and Cluster_Paper	PSD3 FNDC3A MAST2 MAST4 MICAL3 MYBPC3	1.35e-05	190	121	6	93c3188dfeb0b2f9889f8ae9b9c1f2f34129c99b
ToppCell	IPF-Epithelial-Ciliated\|IPF / Disease state, Lineage and Cell class	CFAP300 AK9 CLIC6 ZBBX DNAH12 AADACL2	1.43e-05	192	121	6	354adc1354bf596fbc60dd45c0169688e6f45165
ToppCell	ASK452-Epithelial-Ciliated\|Epithelial / Donor, Lineage and Cell class of Lung cells from Dropseq	CFAP300 AK9 CLIC6 ZBBX DNAH12 IK	1.47e-05	193	121	6	c0d10075862ac878aa05fc49c8b73e470783bf16
ToppCell	severe-Myeloid-Neutrophils_3\|Myeloid / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs	ACOX1 MSL1 F5 UBN1 HCLS1 MAST3	1.47e-05	193	121	6	f4d43dfbf4115dd0f843ea5cf08049220342a047
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	ENOSF1 MAST4 GLDC PKHD1 MICAL3 FAM135A	1.51e-05	194	121	6	7002937e8903e037332a215d00fbc7c7843b33f2
ToppCell	ASK452-Epithelial-Ciliated\|ASK452 / Donor, Lineage and Cell class of Lung cells from Dropseq	CFAP300 AK9 CLIC6 ZBBX DNAH12 IK	1.51e-05	194	121	6	5aeb44657ab6f61b1abf98af28d3397d8e44c1aa
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	FAT4 COL12A1 CCN4 SRPX2 CYP7B1 GFPT2	1.65e-05	197	121	6	9b480f9c799a244bfee64487abd8a1bf07c9a3a2
ToppCell	Primary_Visual_cortex_(V1C)-Neuronal\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	MAP1B COPG2 RTN1 CSRNP3 SYP RIMS1	1.70e-05	198	121	6	8ab40fae14fe02e39bc8c8da187a5cd60c787643
ToppCell	NS-critical-d_07-13\|critical / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	PPP4R1 PSD3 NDFIP2 CLIC6 SRPX2 F11R	1.70e-05	198	121	6	a6e11c87b31beffb6af190c64b4ef3ee1d9dab8d
ToppCell	LPS_only-Epithelial_airway-airway_epithelial\|LPS_only / Treatment groups by lineage, cell group, cell type	CLIC6 ZBBX TRPV6 ALB CTSV MYBPC1	1.70e-05	198	121	6	e035380578c01b0243bfef29ca9b50cc17cce771
ToppCell	LPS_only-Epithelial_airway\|LPS_only / Treatment groups by lineage, cell group, cell type	CLIC6 ZBBX TRPV6 ALB CTSV MYBPC1	1.70e-05	198	121	6	ba090210392e001a3f7bdf09371b3f0e0c8c7ef3
ToppCell	Bronchial-10x5prime-Stromal-Fibroblastic-Fibro_myofibroblast\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	FAT4 COL12A1 MAP1B CCN4 SRPX2 GFPT2	1.75e-05	199	121	6	21335475bbfbad8a6943b8076a6c1c67f3eec5d3
ToppCell	Tracheal-NucSeq-Stromal-Schwann-Schwann_Myelinating\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	FAT3 AATK MAP1LC3B2 GLDC TAF7L PKHD1	1.75e-05	199	121	6	4e4bdcd2e8b518156d5ebd294804180acaa3566b
ToppCell	LPS_IL1RA-Endothelial-Endothelial-Gen_Cap\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	FAT4 COL12A1 TEK KMT2C MAST4 FAM135A	1.80e-05	200	121	6	dccec522ab0d7fff62ad6273b02aa9022dbbb8eb
ToppCell	NS-critical-d_07-13-Epithelial-unknown_epithelial\|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	CDKN1C RHBDF1 HECTD4 RIMS1 GFPT2	4.18e-05	141	121	5	33ad925ff7be3c682741a6328216a89f9d4033e9
ToppCell	Mild/Remission-B_intermediate-14\|Mild/Remission / disease group and sub_cluster of B and Plasma cells(res = 0.5)	CATSPERE GCNT2 DLGAP3 SYP GEN1	4.18e-05	141	121	5	69e32125a0e8f0c8561e5e7a93607f368f09546f
ToppCell	Fetal_29-31_weeks-Epithelial-lung_neuroendocrine_cell_(PNEC)-D062\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	MYO7B RUNDC3A SNX31 ALB MYBPC1	4.32e-05	142	121	5	819e983688d126d89a71abc03d72525cc759a347
ToppCell	3'-GW_trimst-1-SmallIntestine-Mesenchymal-myocytic-myofibroblast_(RSPO2+)\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	FAT4 MAST2 NRXN3 GID4 RIMS1	4.47e-05	143	121	5	39060dc1d87505a16e2df95140087c731f099570
ToppCell	TCGA-Breast-Primary_Tumor-Breast_Carcinoma-Infiltrating_Ductal_and_Lobular_Carcinoma-6\|TCGA-Breast / Sample_Type by Project: Shred V9	COL12A1 PSD3 CLIC6 CCN4 NRXN3	5.44e-05	149	121	5	3904f8ce9078de238600ceceee0116af52256a1c
ToppCell	Globus_pallidus-Neuronal-Excitatory-eN3(Slc17a7_Gad1Gad2)-Drd1\|Globus_pallidus / BrainAtlas - Mouse McCarroll V32	CLIC6 TAF7L PCSK9 MYBPC3	5.79e-05	77	121	4	10969743351c49a1d6d8ae1ef93098e7786ca3fe
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Degenerative_Connecting_Tubule_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	F9 ZBBX TRPV6 RIMS1 CTSV	6.36e-05	154	121	5	9316732964a819a8e935a952faa3823109f90b77
ToppCell	3'-Distal_airway-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.0.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	AGMO RIMS1 MAPK11 MYBPC1 MYBPC3	6.55e-05	155	121	5	62b59cb32b12bd55b19e98786a866d788fc9e4bf
ToppCell	facs-Liver-Hepatocytes\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	F5 F9 GLDC AGMO SERPIND1	6.76e-05	156	121	5	e2cda3ad4e5f44a80133864c5a38b766afb952ce
ToppCell	Control-Treg\|World / Disease group and Cell class	NDFIP2 DLGAP3 MAST4 CYP7B1 PCSK9	7.84e-05	161	121	5	ead9f5a491321f9e307f7c97e47a4ca124f59bb6
ToppCell	3'-Parenchyma_lung-Epithelial-Airway_epithelium-respiratory_basal_cell-Basal_resting-Basal_resting_L.0.0.0.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	GCNT2 PGM5 F11R NFKBIA FAM135A	7.84e-05	161	121	5	0d863d7d369391dd6148e1de6d6f8033dcb8fe0f
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-proliferative_fibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	BRIP1 CCN4 SRPX2 KLHL30 DHRS7C	8.08e-05	162	121	5	bfaeff19bb56598fdc8c82be71d51787cf13928f
ToppCell	facs-Diaphragm-Limb_Muscle-24m\|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FAT3 NRXN3 CSRNP3 NFKBIA PKHD1	9.86e-05	169	121	5	12bdc709bc000d7f9061ecd9fbd57233eaacb7e2
ToppCell	Control-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_2\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	DCHS2 FAT3 HECTD4 PSD3 KCNS3	1.01e-04	170	121	5	5570c0e825bca77613bf0ebde620cf744fa1cb84
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	FAT4 RNF31 MAP1B SRPX2 GFPT2	1.04e-04	171	121	5	972fab891135bd755d5526cbc5a963200067b0a6
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Cycling_Myofibroblast-\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	BRIP1 COL12A1 MAP1B CCN4 CCDC15	1.04e-04	171	121	5	b0373ed8283ee1792b6a490bff93906546978593
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Cycling_Myofibroblast\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	BRIP1 COL12A1 MAP1B CCN4 CCDC15	1.04e-04	171	121	5	b92963f9f247d2e5e2e6c51c6dbf70e527cd2f55
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast-\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	FAT4 RNF31 MAP1B SRPX2 GFPT2	1.04e-04	171	121	5	2a77ed79c6f2e700e789c80451a70ecb31639719
ToppCell	nucseq-Epithelial-Epithelial_Neuro-Secretory-PNEC\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	MAP1B F5 RUNDC3A SYP CTSV	1.04e-04	171	121	5	f4321133190a3df9d31f5d4021a464d3840145f1
ToppCell	nucseq-Epithelial-Epithelial_Neuro-Secretory-PNEC-PNEC\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	MAP1B F5 RUNDC3A SYP CTSV	1.04e-04	171	121	5	ed4fb6c84579d99df33de5f8f928c3cd2f3d3d72
ToppCell	nucseq-Epithelial-Epithelial_Neuro-Secretory\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	MAP1B F5 RUNDC3A SYP CTSV	1.07e-04	172	121	5	d0cdedd734406988a9a93d7300c7b1a8b4b45c38
ToppCell	Children_(3_yrs)-Epithelial-lung_goblet_cell-D139\|Children_(3_yrs) / Lineage, Cell type, age group and donor	DCHS2 CLIC6 NRXN3 TRPV6 RIMS1	1.10e-04	173	121	5	464267a2ff3f5c387b6c9c6fa4dab135a221f448
ToppCell	E16.5-Immune-Immune_Myeloid-Granulocytic-Basophil\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	FAT3 F5 TNRC18 CSRNP3 HCLS1	1.10e-04	173	121	5	2cba41c3d9d3076f703115d19729073a3ac3feb6
ToppCell	E16.5-Immune-Immune_Myeloid-Granulocytic-Basophil-Basophil_mature\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	FAT3 F5 TNRC18 CSRNP3 HCLS1	1.10e-04	173	121	5	11d69a4ab4a87b8820cd3bd204de8c4124450a90
ToppCell	droplet-Pancreas-Exocrine-21m-Epithelial-pancreatic_ductal_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CFAP300 FAT3 CLIC6 CCNA1 ALB	1.13e-04	174	121	5	a0ccda8fd6f55251cdeff24cf66e72e4a31d2104
ToppCell	wk_15-18-Epithelial-Distal_epithelial-type_I_pneumocyte\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	TEX14 AATK F11R TRPV6 ALB	1.13e-04	174	121	5	2cd6638b361ca05ab83d09ce657194aed97873b7
ToppCell	droplet-Kidney-KIDNEY-30m-Mesenchymal-podocyte\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DET1 CLIC6 RTN1 PGM5 YEATS2	1.16e-04	175	121	5	31f0fb2e47e357dbf9c15436b7df85b3c370ded7
ToppCell	5'-Adult-LargeIntestine-Epithelial-neuro-epithelial-EC_cells_(TAC1+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	F5 ZBBX RUNDC3A SYP KCNS3	1.16e-04	175	121	5	182e45f5c02214d6b9f317ff5dc43af8b42de978
ToppCell	facs-Large_Intestine-Distal-18m-Epithelial-Brush_cell_of_epithelium_proper_of_large_intestine\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CDKN1C TEK DLGAP3 SRPX2 MAST4	1.16e-04	175	121	5	f24b664b9056b5976bf2222e8013f15c09e049ad
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast-\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	FAT4 COL12A1 CCN4 CSRNP3 GFPT2	1.19e-04	176	121	5	9bc87cd5cda2372e1bce94c9dfd408eb1dfd8d0c
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	FAT4 COL12A1 CCN4 CSRNP3 GFPT2	1.19e-04	176	121	5	3f8274a7ab67f9f8a8923193763a5543cfe4defa
ToppCell	COVID-19-Myeloid-MoAM4\|COVID-19 / Condition, Lineage and Cell class	RAP2A RTN1 KLHL30 CYP7B1 MAP2K5	1.22e-04	177	121	5	ca5d0c3d5c700bbe4c2da068eb02be6229afb9a0
ToppCell	3'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_II_pneumocyte-AT2-AT2_L.0.1.2.3\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	LBP AATK PKHD1 KCNS3 SERPIND1	1.26e-04	178	121	5	f3b5eeca6081d65d48824b5d13e3b8eb5fdeb2dd
ToppCell	facs-Brain_Non-Myeloid-Hippocampus_-18m-Mesenchymal-ependymal_cell\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CFAP300 CLIC6 LBP F5 ZBBX	1.29e-04	179	121	5	9d7e39357b269d30ff1e8007a91f8645f3d80e73
ToppCell	droplet-Bladder-nan-24m-Epithelial-nan\|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CDKN1C FAT3 LBP AATK GFPT2	1.29e-04	179	121	5	dfd9d29281510d32f1a2e8336d2e58ef496cfd1d
ToppCell	Fetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)-D150\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	CDKN1C CLIC6 GCNT2 NRXN3 MAST4	1.29e-04	179	121	5	815b959ce8721c5ded70c0ca6e318dafc691746e
ToppCell	facs-Brain_Non-Myeloid-Hippocampus_-18m-Mesenchymal-Ependyma\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CFAP300 CLIC6 LBP F5 ZBBX	1.29e-04	179	121	5	1611e11f5f74432627e2f57a27e352b1e46be618
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_ascending_limb_epithelial_cell-Ascending_Thin_Limb_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	FAT3 GCNT2 DNAH17 NUP93 PCSK9	1.29e-04	179	121	5	55bc69f107fc710db7617c428575792adfdbbcc1
ToppCell	facs-Lung-24m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell-pulmonary_artery_endothelial_cell_l25\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	COL12A1 TEK BRWD3 F11R FAM135A	1.32e-04	180	121	5	baa5825e6ce23a98d9c21d024a4b0ab8ba353d0c
ToppCell	Children_(3_yrs)-Epithelial-club_cell-D046\|Children_(3_yrs) / Lineage, Cell type, age group and donor	CLIC6 TEX14 NRXN3 MAST4 RIMS1	1.32e-04	180	121	5	b509c7d6bdfba672065fb722874bdc68de72ba1c
ToppCell	facs-Lung-24m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	COL12A1 TEK BRWD3 F11R FAM135A	1.32e-04	180	121	5	2d608b9394d28d19cfc85c6ac94003d5177c8a92
ToppCell	facs-Lung-24m-Endothelial-arterial_endothelial\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	COL12A1 TEK BRWD3 F11R FAM135A	1.32e-04	180	121	5	0f9b27054358c4737eed06c8ea01987cccc3cb55
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast-\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	COL12A1 MAP1B FAT3 CCN4 SRPX2	1.36e-04	181	121	5	c6d2a13df3b74fade3b0c71e285b4c14c8e52413
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	COL12A1 MAP1B FAT3 CCN4 SRPX2	1.36e-04	181	121	5	c62b0a2422377ffadaab63edd538e87a06fa5017
ToppCell	facs-Liver-Hepatocytes-24m-Epithelial\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	F5 F9 MIA2 GLDC PCSK9	1.39e-04	182	121	5	770ce9f3f4538d0181a0181543841bc964c68274
ToppCell	368C-Epithelial_cells-Epithelial-F_(Ciliated)-\|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)	CATSPERE CFAP300 ZBBX DNAH12 CCNA1	1.39e-04	182	121	5	975f6275777fc578eba528e50f69891c66ec44ad
ToppCell	5'-Airway_Nasal-Epithelial-Airway_epithelium-brush_cell_of_trachebronchial_tree-Tuft\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	BRIP1 TIGD1 CTSV WNK3 DOP1B	1.39e-04	182	121	5	d1c3cc2942faec7527a3c25869fd65c17899e5e4
ToppCell	368C-Epithelial_cells-Epithelial-F_(Ciliated)\|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)	CATSPERE CFAP300 ZBBX DNAH12 CCNA1	1.39e-04	182	121	5	f8c28fa76751062c4cfba0db8af1b377f947f739
ToppCell	facs-Liver-Hepatocytes-24m-Epithelial-nan\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	F5 F9 MIA2 GLDC PCSK9	1.39e-04	182	121	5	77ab860e2add49dad0c1ffbfc64278ad499dfbd5
ToppCell	facs-Liver-Hepatocytes-24m-Epithelial-hepatocyte\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	F5 F9 MIA2 GLDC PCSK9	1.39e-04	182	121	5	4921c7d5687cc79f896b39753bb621d7e3d2972f
ToppCell	5'-Airway_Nasal-Epithelial-Airway_epithelium-brush_cell_of_trachebronchial_tree\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	BRIP1 TIGD1 CTSV WNK3 DOP1B	1.39e-04	182	121	5	92f83f29e358000cd86a709eb8b6199761ffe8bd
ToppCell	5'-Airway_Nasal-Epithelial-Airway_epithelium-brush_cell_of_trachebronchial_tree-Tuft-Tuft_L.0.7.1.0\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	BRIP1 TIGD1 CTSV WNK3 DOP1B	1.39e-04	182	121	5	02baca9a72c7b559c3e452693b3b134af804c868
ToppCell	droplet-Heart-HEART_(LV+RV_ONLY)-30m-Neuronal-cardiac_neuron\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL12A1 F5 AATK SNX31 SERPIND1	1.43e-04	183	121	5	876b4f128c2168fdae7488201ff44f19c06c8415
ToppCell	droplet-Heart-HEART_(LV+RV_ONLY)-30m-Neuronal\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL12A1 F5 AATK SNX31 SERPIND1	1.43e-04	183	121	5	b190b650e61b1b20baf5e42d04acac82d3fd1400
ToppCell	E17.5-Epithelial-airway_epithelial_cell\|E17.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	AK9 ZBBX DNAH12 CCNA1 SNX31	1.43e-04	183	121	5	07cebb0e186e1bff14ac2a6bb6f8412d4aaa2350
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_ascending_limb_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	FAT3 GCNT2 DNAH17 NUP93 PCSK9	1.43e-04	183	121	5	83592c332b1e82673f993d37c7f480befdc3dcda
ToppCell	E17.5-Epithelial-airway_epithelial_cell-club_cell\|E17.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	AK9 ZBBX DNAH12 CCNA1 SNX31	1.43e-04	183	121	5	e8e85e5be909f9cd85a6a041190bfcb855dfa1a4
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FAT4 COL12A1 MYO7B FAT3 PKHD1	1.47e-04	184	121	5	2cbed6462fea2622871bb7e49b0df3d984239281
ToppCell	TCGA-Pancreas-Primary_Tumor-Pancreatic_Adenocarcinoma-Ductal_Adenocarcinoma-4\|TCGA-Pancreas / Sample_Type by Project: Shred V9	FAT4 REV3L TEK CSRNP3 CYP7B1	1.47e-04	184	121	5	67164bb6bcae7322cb89b585c7aa10bce35b0ecd
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FAT4 COL12A1 MYO7B FAT3 PKHD1	1.47e-04	184	121	5	ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FAT4 COL12A1 MYO7B FAT3 PKHD1	1.47e-04	184	121	5	2b19a8c5f823e00812908b23e66bb4e563278aff
ToppCell	PCW_05-06-Epithelial-Epithelial_alveolar-distal-epi_SOX9^high_Etv5^high_distal_(10)\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	CLIC6 GCNT2 GLDC PKHD1 TRPV6	1.47e-04	184	121	5	fa4915b0498f3069fd5ef497286445528f75187e
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	COL12A1 MAP1B CCN4 SNX31 RIMS1	1.51e-04	185	121	5	7092436b4db90289516ed130ade596e3021cffaf
ToppCell	facs-Brain_Non-Myeloid-Cerebellum-3m-Neuronal-neuron\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PSD3 RTN1 NRXN3 KCNJ9 SYP	1.51e-04	185	121	5	70de48988c1f8e0809afc8092b663aa439d8e528
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte-\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	COL12A1 MAP1B CCN4 SNX31 RIMS1	1.51e-04	185	121	5	a8ca7819066d5297ef6966e7f3e2c9f8a7673fdc
ToppCell	facs-Brain_Non-Myeloid-Cerebellum\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RTN1 NRXN3 KCNJ9 RIMS1 MYBPC1	1.51e-04	185	121	5	c083a4974590b9ed3ecafedd3e9cdebc5047fe39
ToppCell	367C-Endothelial_cells-Endothelial-B_(Artery)-\|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)	MYO7B TEX14 SRPX2 AATK MAST4	1.51e-04	185	121	5	b57dae20c21f984edd2acee4344d86f033108ebf
ToppCell	367C-Endothelial_cells-Endothelial-B_(Artery)\|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)	MYO7B TEX14 SRPX2 AATK MAST4	1.51e-04	185	121	5	d3b054d203e575c1bb5455aa7a2e551a0957a760
Drug	Dinoprost trometamol [38362-01-5]; Down 200; 8.4uM; MCF7; HT_HG-U133A	RNF31 PSD3 GCNT2 ZNF783 RUNDC3A DNAH17 TRPV6 PPIL2 GFPT2	1.14e-06	196	122	9	5409_DN
Drug	(cis-) Nanophine [5072-45-7]; Down 200; 26.8uM; MCF7; HT_HG-U133A	ARHGAP35 MAST2 DICER1 ZNF783 TRPV6 PPIL2 MAPK11 MAP2K5 DOP1B	1.35e-06	200	122	9	6049_DN
Drug	Iopanoic acid [96-83-3]; Down 200; 7uM; MCF7; HT_HG-U133A	INPP5K ARHGAP35 MAST2 MAST4 TRPV6 GFPT2 MAPK11 MAP2K5	1.01e-05	194	122	8	5448_DN
Drug	Midecamycin [35457-80-8]; Up 200; 5uM; MCF7; HT_HG-U133A	UBE3B PSD3 FNDC3A ARHGAP35 F5 F11R PPIL2 MAPK11	1.09e-05	196	122	8	5345_UP
Drug	Melatonin [73-31-4]; Down 200; 17.2uM; MCF7; HT_HG-U133A	INPP5K PSD3 GCNT2 ZNF783 MIA2 TRPV6 PPIL2 MAP2K5	1.17e-05	198	122	8	5393_DN
Drug	Ketotifen fumarate [34580-14-8]; Down 200; 9.4uM; PC3; HT_HG-U133A	FAT4 RNF31 PSD3 MAST4 F11R CCNA1 SERPIND1 MAST3	1.26e-05	200	122	8	5842_DN
Drug	trichostatin A, Streptomyces sp.; Up 200; 1uM; MCF7; HT_HG-U133A	MAP1B TEX14 PPP2R1B CCNA1 GFPT2 CTSV MAST3	5.95e-05	183	122	7	6434_UP
Drug	AC1LAFI2	F5 F9 SERPIND1	6.52e-05	15	122	3	CID000467477
Drug	PHA-00846566E [724718-26-7]; Down 200; 10uM; PC3; HT_HG-U133A	ENOSF1 INPP5K FNDC3A ARHGAP35 ZNF783 F11R PPIL2	7.78e-05	191	122	7	7086_DN
Drug	actarit	ENOSF1 FNDC3A SYP	7.99e-05	16	122	3	CID000002018
Drug	Trichlorfon [52-68-6]; Down 200; 15.6uM; MCF7; HT_HG-U133A	INPP5K ARHGAP35 ZNF783 PPIL2 MAPK11 MAP2K5 MAST3	8.31e-05	193	122	7	5989_DN
Drug	Azaguanine-8 [134-58-7]; Down 200; 26.2uM; MCF7; HT_HG-U133A	INPP5K PSD3 ZFC3H1 MAST2 YEATS2 MAPK11 DOP1B	8.58e-05	194	122	7	1670_DN
Drug	Roxithromycin [80214-83-1]; Down 200; 4.8uM; PC3; HT_HG-U133A	CDKN1C DET1 F5 AATK CSRNP3 CYP7B1 MAP2K5	8.58e-05	194	122	7	4192_DN
Drug	Ethambutol dihydrochloride [1070-11-7]; Down 200; 14.4uM; PC3; HT_HG-U133A	CDKN1C GBF1 RHBDF1 GCNT2 ARHGAP35 MAST2 TRPV6	8.58e-05	194	122	7	4001_DN
Drug	Picrotoxinin [17617-45-7]; Down 200; 13.6uM; PC3; HT_HG-U133A	ARHGAP35 RUNDC3A MIA2 CSRNP3 GID4 CYP7B1 KCNS3	8.86e-05	195	122	7	4260_DN
Drug	Hydralazine hydrochloride [304-20-1]; Down 200; 20.4uM; MCF7; HT_HG-U133A	CDKN1C ARHGAP35 F11R TRPV6 PPIL2 MAPK11 MAST3	8.86e-05	195	122	7	2311_DN
Drug	Indomethacin [53-86-1]; Down 200; 11.2uM; HL60; HT_HG-U133A	ACOX1 FNDC3A F5 YEATS2 PPP2R1B CCDC15 MICAL3	9.15e-05	196	122	7	2377_DN
Drug	Ipratropium bromide [22254-24-6]; Up 200; 9.8uM; MCF7; HT_HG-U133A	PSD3 LBP DICER1 TAF7L PPIL2 MAP2K5 MAST3	9.15e-05	196	122	7	2762_UP
Drug	CAY10397; Down 200; 10uM; PC3; HT_HG-U133A	BRIP1 RNF31 PSD3 REV3L DICER1 ZNF783 F11R	9.15e-05	196	122	7	7087_DN
Drug	Folinic acid calcium salt [6035-45-6]; Up 200; 7.8uM; MCF7; HT_HG-U133A	INPP5K GCNT2 ARHGAP35 MAST2 F11R CYP7B1 MAP2K5	9.44e-05	197	122	7	3442_UP
Drug	Bromopride [4093-35-0]; Up 200; 11.6uM; PC3; HT_HG-U133A	FNDC3A TEX14 MAST4 CSRNP3 DNAH17 TAF7L DOP1B	9.44e-05	197	122	7	3719_UP
Drug	Vincamine [1617-90-9]; Down 200; 11.2uM; PC3; HT_HG-U133A	CDKN1C FNDC3A F5 NRXN3 TRPV6 PPIL2 MAP2K5	9.44e-05	197	122	7	3784_DN
Drug	Alprostadil [745-65-3]; Up 200; 11.2uM; MCF7; HT_HG-U133A	ZNF783 PPP2R1B DNAH17 PPIL2 MAP2K5 DOP1B MYBPC3	9.44e-05	197	122	7	7358_UP
Drug	Azaperone [1649-18-9]; Down 200; 12.2uM; MCF7; HT_HG-U133A	GBF1 PSD3 MAST2 GID4 KLHL21 PPIL2 MICAL3	9.44e-05	197	122	7	7231_DN
Drug	Edrophonium chloride [116-38-1]; Up 200; 19.8uM; MCF7; HT_HG-U133A	FAT4 DNAH17 CYP7B1 PPIL2 MAP2K5 MAST3 MYBPC3	9.44e-05	197	122	7	5001_UP
Drug	Tracazolate hydrochloride [41094-88-6]; Up 200; 11.8uM; MCF7; HT_HG-U133A	MAP1B F5 RUNDC3A NRXN3 DNAH17 MAPK11 MAST3	9.75e-05	198	122	7	4964_UP
Drug	Alfaxalone [23930-19-0]; Down 200; 12uM; MCF7; HT_HG-U133A	INPP5K ARHGAP35 MAST2 MAST4 TRPV6 PPIL2 MAPK11	9.75e-05	198	122	7	5451_DN
Drug	Avermectin B1 [71751-41-2]; Up 200; 4.8uM; HL60; HT_HG-U133A	CDKN1C RAP2B ACOX1 PSD3 ARHGAP35 RTN1 CTSV	9.75e-05	198	122	7	2519_UP
Drug	Mafenide hydrochloride [138-37-4]; Up 200; 18uM; PC3; HT_HG-U133A	CDKN1C GBF1 ARHGAP35 ZNF783 CSRNP3 CCNA1 RIMS1	9.75e-05	198	122	7	2124_UP
Drug	Alfuzosin hydrochloride [81403-68-1]; Down 200; 9.4uM; MCF7; HT_HG-U133A	RNF31 PSD3 ARHGAP35 MAST4 MIA2 MICAL3 MAST3	9.75e-05	198	122	7	5242_DN
Drug	alpha-estradiol; Down 200; 0.01uM; PC3; HT_HG-U133A	CDKN1C RHBDF1 ARHGAP35 AATK KCNS3 TRPV6 MAPK11	9.75e-05	198	122	7	4434_DN
Drug	Cloperastine hydrochloride [14984-68-0]; Up 200; 11uM; HL60; HT_HG-U133A	CDKN1C RAP2B TEK RUNDC3A SRPX2 MAP2K5 MYBPC1	9.75e-05	198	122	7	2549_UP
Drug	beta- Belladonnine dichloroethylate [191355-47-2]; Up 200; 6uM; MCF7; HT_HG-U133A	PSD3 LBP ZNF783 RUNDC3A CYP7B1 PPIL2 MAST3	1.01e-04	199	122	7	4984_UP
Drug	Methotrexate [59-05-2]; Up 200; 8.8uM; PC3; HG-U133A	CDKN1C LBP MAST4 PPIL2 MAPK11 MAP2K5 MAST3	1.01e-04	199	122	7	1957_UP
Drug	Mephenesin [59-47-2]; Up 200; 22uM; PC3; HT_HG-U133A	CDKN1C MAP1B UBE3B MAST2 PPIL2 MAP2K5 DOP1B	1.01e-04	199	122	7	7374_UP
Drug	Cloxacillin sodium salt [642-78-4]; Up 200; 8.8uM; MCF7; HT_HG-U133A	UBE3B MIA2 GID4 PPIL2 MICAL3 MAST3 DOP1B	1.04e-04	200	122	7	7483_UP
Drug	Oxantel pamoate [68813-55-8]; Up 200; 6.6uM; MCF7; HT_HG-U133A	CDKN1C RAP2B GCNT2 ARHGAP35 PPP2R1B RUNDC3A GFPT2	1.04e-04	200	122	7	2632_UP
Disease	signal-transducing adaptor protein 1 measurement	LBP ALB	9.46e-05	4	118	2	EFO_0803075
Disease	physical activity measurement, body mass index	RASA2 MAST2 NRXN3 PKHD1 MAP2K5	9.74e-05	114	118	5	EFO_0004340, EFO_0008002
Disease	Parkinson disease	BRIP1 COL12A1 GBF1 DNAH17 KCNS3 RIMS1 GFPT2	3.18e-04	321	118	7	MONDO_0005180
Disease	Venous Thromboembolism	F5 SERPIND1	4.37e-04	8	118	2	C1861172
Disease	obstructive jaundice (biomarker_via_orthology)	LBP ALB	6.99e-04	10	118	2	DOID:13603 (biomarker_via_orthology)
Disease	sodium measurement	MAST2 NRXN3 CSRNP3 PKHD1	7.92e-04	103	118	4	EFO_0009282
Disease	1-methylxanthine measurement	PSD3 CYP7B1	8.52e-04	11	118	2	EFO_0021174
Disease	mean arterial pressure	ENOSF1 PCNX3 HECTD4 NDUFS3 YEATS2 USP8 PKHD1 SNX31	9.13e-04	499	118	8	EFO_0006340
Disease	osteosarcoma, overall survival	GLDC AGMO	1.02e-03	12	118	2	EFO_0000637, EFO_0000638
Disease	squamous cell carcinoma, multiple keratinocyte carcinoma susceptibility measurement, basal cell carcinoma	BRIP1 PKHD1	1.20e-03	13	118	2	EFO_0000707, EFO_0004193, EFO_0007932
Disease	Carcinoma, Granular Cell	CDKN1C FAT4 KMT2C CYP7B1	1.23e-03	116	118	4	C0205644
Disease	Adenocarcinoma, Tubular	CDKN1C FAT4 KMT2C CYP7B1	1.23e-03	116	118	4	C0205645
Disease	Adenocarcinoma, Oxyphilic	CDKN1C FAT4 KMT2C CYP7B1	1.23e-03	116	118	4	C0205642
Disease	Carcinoma, Cribriform	CDKN1C FAT4 KMT2C CYP7B1	1.23e-03	116	118	4	C0205643
Disease	Adenocarcinoma, Basal Cell	CDKN1C FAT4 KMT2C CYP7B1	1.23e-03	116	118	4	C0205641
Disease	Adenocarcinoma	CDKN1C FAT4 KMT2C CYP7B1	1.23e-03	116	118	4	C0001418
Disease	Antithrombotic agent use measurement	HECTD4 F5 PCSK9	1.41e-03	55	118	3	EFO_0009925
Disease	Adenocarcinoma of lung (disorder)	ARHGAP35 MSH6 AATK UCK2 ALB	1.46e-03	206	118	5	C0152013
Disease	cholesterol to total lipids in large LDL percentage	NUP93 PCSK9 MYBPC3	1.48e-03	56	118	3	EFO_0022235
Disease	comparative body size at age 10, self-reported	RASA2 NDUFS3 AATK NRXN3 MAST4 PKHD1 MAP2K5	1.53e-03	420	118	7	EFO_0009819
Disease	fibroblast growth factor basic measurement	MAP1B PCNX3 NRXN3	1.72e-03	59	118	3	EFO_0008130
Disease	Brain Ischemia	F5 NFKBIA ALB	1.81e-03	60	118	3	C0007786
Disease	Cerebral Ischemia	F5 NFKBIA ALB	1.81e-03	60	118	3	C0917798
Disease	tea consumption measurement	HECTD4 MSH6 NRXN3 PKHD1	1.82e-03	129	118	4	EFO_0010091
Disease	pancreatitis	HECTD4 MYBPC1	1.83e-03	16	118	2	EFO_0000278
Disease	methylcobalamin deficiency type cblE, brain serotonin transporter measurement	PSD3 AGMO	1.83e-03	16	118	2	EFO_0004569, MONDO_0009354
Disease	response to radiation, Urinary retention	AGMO LRPAP1	2.07e-03	17	118	2	GO_0009314, HP_0000016
Disease	food allergy measurement, parental genotype effect measurement	DCHS2 CYP7B1	2.33e-03	18	118	2	EFO_0005939, EFO_0007016
Disease	venous thromboembolism, fibrinogen measurement	DCHS2 HECTD4 F5	2.48e-03	67	118	3	EFO_0004286, EFO_0004623
Disease	congenital heart disease (implicated_via_orthology)	KMT2C MYBPC1 MYBPC3	2.70e-03	69	118	3	DOID:1682 (implicated_via_orthology)
Disease	maximal midexpiratory flow rate	BRIP1 MICAL3	2.87e-03	20	118	2	EFO_0004313
Disease	phosphatidylcholine 34:2 measurement	MAST2 F9	2.87e-03	20	118	2	EFO_0010376
Disease	coagulation factor V measurement	F5 MAST4	2.87e-03	20	118	2	EFO_0008087
Disease	seborrheic dermatitis	TNRC18 MAST4	2.87e-03	20	118	2	EFO_1000764
Disease	coronary artery disease	FAT4 MAP1B PCNX3 UBE3B HECTD4 PSD3 TEK PPP2R1B MAST4 PKHD1 KCNS3 PCSK9	3.02e-03	1194	118	12	EFO_0001645
Disease	bone density, lean body mass	CSRNP3 GID4	3.17e-03	21	118	2	EFO_0003923, EFO_0004995
Disease	sex interaction measurement, bilirubin measurement	COL12A1 PSD3	3.48e-03	22	118	2	EFO_0004570, EFO_0008343
Disease	granulocyte count	RASA2 HECTD4 MAST2 USP8 KCNJ9	3.61e-03	254	118	5	EFO_0007987

Protein segments in the cluster

Peptide	Gene	Start	Entry
SELLPFLTDTIYDED	PPP2R1B	61	P30154
DEYITVTDTTFVDIP	AADACL2	76	Q6P093
EVDETYVPKEFNAET	ALB	516	P02768
PDEEERYLFVESSHT	CATSPERE	86	Q5SY80
LDSEESYPYVAVDEI	CTSV	196	O60911
SETSFQTLEEVPDYV	AGMO	26	Q6ZNB7
EEAASLEAPLSEEEY	DUX4L4	401	P0CJ87
FDQLSYEVTLSESEP	FAT4	996	Q6V0I7
DYQDVIDTPVDFSTV	BRWD3	1361	Q6RI45
DIFADLESYPDFSEI	CCN4	351	O95388
YSTEAEFEEPRVIDL	LRPAP1	246	P30533
YEDDLLTVSAVFPEV	DET1	261	Q7L5Y6
YLDPSKAVEEDDFVV	DICER1	1511	Q9UPY3
LPDEIDAYSTEDVTV	CLIC6	611	Q96NY7
LDFTQESEPSYISDV	NUP93	156	Q8N1F7
EPESEVFEITDFTTA	RAB3GAP1	6	Q15042
IEDFYRKEIEVDSSP	RAP2A	36	P10114
IEDFYRKEIEVDSSP	RAP2B	36	P61225
IEDFYRKEIEVDSSP	RAP2C	36	Q9Y3L5
IRIDATTVFVDPYEE	PPIL2	426	Q13356
TTVFVDPYEEADAQI	PPIL2	431	Q13356
KEPDDYSNFVIEDSV	RASA2	791	Q15283
EVDYASFHETFEVPT	KCNJ9	316	Q92806
DYIDIVDSLSVSPTD	SERPIND1	91	P05546
TLDVVEVESYDPYTD	KLHL30	386	Q0D2K2
VSTPISEVYESEKDE	MAP1LC3B	91	Q9GZQ8
TDSFEYVDPVDGTVT	PGM5	476	Q15124
TPATSIEDFSEVYLV	MAPK11	91	Q15759
LPVTTEIDSFADIDY	LBP	216	P18428
PSEEYEVTTEDGYIL	LIPN	46	Q5VXI9
SVEEIPFADDVEDTY	MICAL3	1516	Q7RTP6
SGEFDIIAYTDPELD	KMT2C	2751	Q8NEZ4
LSEFTEYLSESVEVP	MAP1B	226	P46821
EDESETIPTDKTVTY	MAP1B	2181	P46821
DLTYDETTSDEEKIP	MAGEB18	181	Q96M61
ETLSEEEAGFPLAYT	GCNT2	86	Q8N0V5
ATFPVYLSEEETEQL	DOP1B	761	Q9Y3R5
YSIADSFEIETEPQA	CSRNP3	311	Q8WYN3
DPDYSAAYVVIETDA	ENOSF1	31	Q7L5Y1
SSVPYFSVEEEDGSE	FAM135A	1231	Q9P2D6
SDPTFSLSVDEDYDL	PCNX3	1526	Q9H6A9
DYIEEDSSVFAQSIP	PCSK9	141	Q8NBP7
VLPEATTTAFEYEDE	MAP2K5	51	Q13163
FPDVDYVNSTEAETI	F9	196	P00740
PPTDDEDFYTTFSLV	NRXN3	1421	Q9Y4C0
LGYEFEVIPSDTSDT	DNAH12	2971	Q6ZR08
TESEFTEFTEDELPY	NFKBIA	291	P25963
FYATLAVDTKEEESE	KCNS3	266	Q9BQ31
LTIEEDREFTYPSDV	HECTD4	841	Q9Y4D8
FEEYIPLDSDTVSTT	MSH6	706	P52701
FSSEIEDLPYLSTTE	MSL1	416	Q68DK7
APEFIVSSYDIEVLE	DCHS2	1826	Q6V1P9
PEYTSCEDVELESES	RIMS1	541	Q86UR5
FETEAEDESIYFTPE	BRIP1	1121	Q9BX63
EEYPTLTTFFEGEII	GID4	166	Q8IVV7
VEVPTTSDTEVYGEF	NDFIP2	156	Q9NV92
DSEKYEIFSQPDREE	CFAP300	151	Q9BRQ4
ETTATYDPETQEFIL	ACOX1	151	Q15067
DNTFELSDVVEAYDP	KLHL21	521	Q9UJP4
KGYEFESETDTETIA	GFPT2	136	O94808
EELFNDEDLDYTPTS	BTAF1	166	O14981
PETEYVVTITSYDEV	COL12A1	86	Q99715
EVSITAIYPDESESD	COL12A1	1721	Q99715
VEDLSTALFYDTVPD	DNAH17	4266	Q9UFH2
EVDSDSVPAFYRETV	CDKN1C	81	P49918
ETDESSVPELYGYEV	FNDC3A	296	Q9Y2H6
VYIDISNIPTTEDEF	INPP5K	396	Q9BT40
PEVDEFVYITDDTYT	CCNA1	306	P78396
ATESADSIEIYIPEA	DLGAP3	961	O95886
TEELDFESSPEIYRF	FAT3	531	Q8TDW7
SEPVQLTEAETEYFV	COPG2	631	Q9UBF2
IPQLESEDDTSYFDT	MAST2	801	Q6P0Q8
VPQLEAEDDTSYFDT	MAST3	656	O60307
AEFIPQLESEDDTSY	MAST4	856	O15021
EEEEEKPQTTYSAFI	DNAJC18	216	Q9H819
EESLFEAAYPEIVAV	GEN1	441	Q17RS7
KALVSVTPDEETYDE	GBF1	1136	Q92538
FVEEDLTLSSETGDY	CYP7B1	371	O75881
EEYDVVISTVSPTFI	DHRS7C	211	A6NNS2
AYIDIPETELEIDSF	DSEL	886	Q8IZU8
DTIIYTDESFTPDLN	C9orf72	351	Q96LT7
ELVFDPLSASDTGEY	F11R	196	Q9Y624
EEVYFEPSSSKDSDE	MIA2	536	Q96PC5
EITNFLIPEDDTTYA	MOXD2P	196	A6NHM9
YTAEPIDDSSEEFVN	RUNDC3A	46	Q59EK9
EESTFAPYIDDLSEE	RTN1	256	Q16799
TESDLSIEVEFEYPF	SYP	61	P08247
SFTEYIESPDVENEV	TAF7L	251	Q5H9L4
YSDTAPTEDLIEEVT	AK9	561	Q5TCS8
SEDITDEFLTPDGEY	TEX14	1076	Q8IWB6
DDYSSESDVIIIPSA	PPP4R1	21	Q8TF05
VQSSEDDYAEIDYVP	F5	1531	P12259
TDIEDSDDIPEDTTY	F5	1601	P12259
DYEEVLEPEDSSFSS	HCLS1	396	P14317
DDVTVYLFDQESPTR	AATK	1236	Q6ZMQ8
PTDDEDFYTTFSLVT	NRXN3	416	Q9HDB5
YTDELTPIESAVSVF	NDUFS3	146	O75489
EELSTYPDEVFESPS	RHBDF1	271	Q96CC6
TFDFDAEYIDSPVIL	PKHD1	166	P08F94
EEDIEPSYSLFREDT	ARHGAP35	986	Q9NRY4
DFELPYVSLGSSEVE	SNX31	181	Q8N9S9
EEPDYEESSSLVTDE	CCDC15	256	Q0P6D6
DPATLYEVEELETAT	RNF31	1016	Q96EP0
LGTEFEYTDSESEVK	TNRC18	1906	O15417
VSTPISEVYESEKDE	MAP1LC3B2	91	A6NCE7
ESSIFDYEEDIPSVT	REV3L	656	O60673
IDDYEGFKTSVEEVS	TIGD1	411	Q96MW7
TPEEIFTFIDDYLLS	SRPX2	436	O60687
SAFYIIFQTEDPEEL	TRPV6	546	Q9H1D0
VDLDDEYADTDIPTT	IK	241	Q13123
IFPSSEDDFYVEVER	TEK	566	Q02763
EETVTVYPADVVLFE	UCK2	121	Q9BZX2
VFYSSVDELPSLDSE	UBE3B	811	Q7Z3V4
DSFIDNSEAYDELVP	UBN1	136	Q9NPG3
ELEALESIYPDSFTV	RWDD1	11	Q9H446
EIPLSAEVTTEESFY	PSD3	196	Q9NYI0
EEVSISLDFTYPSLE	USP8	326	P40818
VVTPDDVRYFTNETD	ZFC3H1	1331	O60293
DNIVDPDVYSSDIEK	ZBBX	481	A8MT70
PDVYSSDIEKIEEST	ZBBX	486	A8MT70
RTIKETDPDYEDVSV	YEATS2	6	Q9ULM3
YFSSEEDPIASQLDE	WDR64	96	B1ANS9
VPVTFDDVAVYFSEL	ZNF783	141	Q6ZMS7
SFNLETDTPEEVAYE	WNK3	451	Q9BYP7
YPDTEGKVEDFTELV	GLDC	266	P23378
EEYEFVSPSSVAIAE	MYO7B	1476	Q6PIF6
ESYPDSSTLVIDIAE	MYBPC1	576	Q00872
LTIDDVTPADEADYS	MYBPC3	601	Q14896