Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionvoltage-gated sodium channel activity

SCN11A HCN4 SCN4A HCN3 SCN5A SCN7A SCN8A CACNA1G

4.46e-1426768GO:0005248
GeneOntologyMolecularFunctionsodium channel activity

SCN11A HCN4 SCN4A HCN3 SCN5A SCN7A SCN8A CACNA1G CNGB1

3.31e-1352769GO:0005272
GeneOntologyMolecularFunctionchannel activity

GPM6A SCN11A SLC9C1 PIEZO2 TMC1 HCN4 KCNJ4 KCNJ6 SCN4A HCN3 SCN5A SCN7A SCN8A TRPV3 CACNA1G CNGB1 SLC1A7 RHAG

8.25e-135257618GO:0015267
GeneOntologyMolecularFunctionpassive transmembrane transporter activity

GPM6A SCN11A SLC9C1 PIEZO2 TMC1 HCN4 KCNJ4 KCNJ6 SCN4A HCN3 SCN5A SCN7A SCN8A TRPV3 CACNA1G CNGB1 SLC1A7 RHAG

8.52e-135267618GO:0022803
GeneOntologyMolecularFunctionmonoatomic ion channel activity

GPM6A SCN11A SLC9C1 PIEZO2 TMC1 HCN4 KCNJ4 KCNJ6 SCN4A HCN3 SCN5A SCN7A SCN8A TRPV3 CACNA1G CNGB1 SLC1A7

1.14e-124597617GO:0005216
GeneOntologyMolecularFunctionmetal ion transmembrane transporter activity

GPM6A SCN11A SLC9C1 TMC1 HCN4 KCNJ4 KCNJ6 SCN4A HCN3 SCN5A SCN7A SCN8A SLC39A6 TRPV3 CACNA1G CNGB1 SLC1A7

1.41e-124657617GO:0046873
GeneOntologyMolecularFunctioninorganic cation transmembrane transporter activity

GPM6A SCN11A SLC9C1 TMC1 HCN4 KCNJ4 KCNJ6 SCN4A HCN3 SCN5A SCN7A SCN8A SLC39A6 COX15 TRPV3 CACNA1G CNGB1 SLC1A7 RHAG

1.52e-126277619GO:0022890
GeneOntologyMolecularFunctionmonoatomic cation channel activity

GPM6A SCN11A PIEZO2 TMC1 HCN4 KCNJ4 KCNJ6 SCN4A HCN3 SCN5A SCN7A SCN8A TRPV3 CACNA1G CNGB1

2.72e-123437615GO:0005261
GeneOntologyMolecularFunctionmonoatomic cation transmembrane transporter activity

GPM6A SCN11A SLC9C1 PIEZO2 TMC1 HCN4 KCNJ4 KCNJ6 SCN4A HCN3 SCN5A SCN7A SCN8A SLC39A6 COX15 TRPV3 CACNA1G CNGB1 SLC1A7

4.14e-126647619GO:0008324
GeneOntologyMolecularFunctiontransporter activity

NPC1 GPM6A SCN11A SLC9C1 PIEZO2 TMC1 HCN4 SLC38A9 KCNJ4 KCNJ6 SCN4A HCN3 SCN5A SCN7A SCN8A SLC39A6 COX15 TRPV3 CACNA1G ABCD1 FLVCR2 CNGB1 SLC1A7 RHAG ATP10D

4.53e-1212897625GO:0005215
GeneOntologyMolecularFunctiontransmembrane transporter activity

GPM6A SCN11A SLC9C1 PIEZO2 TMC1 HCN4 SLC38A9 KCNJ4 KCNJ6 SCN4A HCN3 SCN5A SCN7A SCN8A SLC39A6 COX15 TRPV3 CACNA1G ABCD1 FLVCR2 CNGB1 SLC1A7 RHAG

3.76e-1111807623GO:0022857
GeneOntologyMolecularFunctioninorganic molecular entity transmembrane transporter activity

GPM6A SCN11A SLC9C1 TMC1 HCN4 KCNJ4 KCNJ6 SCN4A HCN3 SCN5A SCN7A SCN8A SLC39A6 COX15 TRPV3 CACNA1G CNGB1 SLC1A7 RHAG

4.07e-117587619GO:0015318
GeneOntologyMolecularFunctionsodium ion transmembrane transporter activity

SCN11A SLC9C1 HCN4 SCN4A HCN3 SCN5A SCN7A SCN8A CACNA1G CNGB1 SLC1A7

4.65e-111717611GO:0015081
GeneOntologyMolecularFunctionmonoatomic ion transmembrane transporter activity

GPM6A SCN11A SLC9C1 PIEZO2 TMC1 HCN4 KCNJ4 KCNJ6 SCN4A HCN3 SCN5A SCN7A SCN8A SLC39A6 COX15 TRPV3 CACNA1G CNGB1 SLC1A7

8.78e-117937619GO:0015075
GeneOntologyMolecularFunctiongated channel activity

PIEZO2 TMC1 HCN4 KCNJ4 KCNJ6 HCN3 SCN7A CACNA1G CNGB1 SLC1A7

5.38e-073347610GO:0022836
GeneOntologyMolecularFunctiontransmembrane receptor protein serine/threonine kinase activity

BMPR1A BMPR1B ACVR2A ACVR2B

8.96e-0720764GO:0004675
GeneOntologyMolecularFunctiontransmembrane signaling receptor activity

NPC1 BMPR1A BMPR1B OR4K2 PTPRC OR13C8 SCN7A OR1D5 CCRL2 ADGRF5 ADGRV1 ACVR2A ACVR2B OR1D4 GPR160 ADGRL3 NRP2 OR1D2

2.33e-0613537618GO:0004888
GeneOntologyMolecularFunctionBMP receptor activity

BMPR1A BMPR1B ACVR2A

2.93e-068763GO:0098821
GeneOntologyMolecularFunctionintracellularly cAMP-activated cation channel activity

HCN4 HCN3 CNGB1

6.24e-0610763GO:0005222
GeneOntologyMolecularFunctionintracellularly cyclic nucleotide-activated monoatomic cation channel activity

HCN4 HCN3 CNGB1

1.47e-0513763GO:0005221
GeneOntologyMolecularFunctioncyclic nucleotide-activated monoatomic ion channel activity

HCN4 HCN3 CNGB1

1.47e-0513763GO:0043855
GeneOntologyMolecularFunctiontransmembrane receptor protein kinase activity

BMPR1A BMPR1B ACVR2A ACVR2B NRP2

1.81e-0585765GO:0019199
GeneOntologyMolecularFunctionvoltage-gated monoatomic cation channel activity

TMC1 HCN4 KCNJ4 KCNJ6 HCN3 CACNA1G

2.48e-05152766GO:0022843
GeneOntologyMolecularFunctionvoltage-gated monoatomic ion channel activity

TMC1 HCN4 KCNJ4 KCNJ6 HCN3 CACNA1G

6.80e-05182766GO:0005244
GeneOntologyMolecularFunctionvoltage-gated channel activity

TMC1 HCN4 KCNJ4 KCNJ6 HCN3 CACNA1G

7.23e-05184766GO:0022832
GeneOntologyMolecularFunctionvery-long-chain (3R)-3-hydroxyacyl-CoA dehydratase activity

HACD3 HACD1

8.54e-054762GO:0102158
GeneOntologyMolecularFunctionankyrin binding

PTPRC SCN5A RHAG

8.88e-0523763GO:0030506
GeneOntologyMolecularFunctionligand-gated monoatomic ion channel activity

HCN4 KCNJ4 KCNJ6 HCN3 CNGB1 SLC1A7

9.40e-05193766GO:0015276
GeneOntologyMolecularFunctionligand-gated channel activity

HCN4 KCNJ4 KCNJ6 HCN3 CNGB1 SLC1A7

1.05e-04197766GO:0022834
GeneOntologyMolecularFunctioncAMP binding

HCN4 HCN3 CNGB1

1.15e-0425763GO:0030552
GeneOntologyMolecularFunctioncalcium channel activity

GPM6A TMC1 TRPV3 CACNA1G CNGB1

1.33e-04129765GO:0005262
GeneOntologyMolecularFunctiontransforming growth factor beta receptor activity, type I

BMPR1A BMPR1B

1.42e-045762GO:0005025
GeneOntologyMolecularFunctioninhibin binding

ACVR2A ACVR2B

1.42e-045762GO:0034711
GeneOntologyMolecularFunctionligand-gated monoatomic cation channel activity

HCN4 KCNJ4 KCNJ6 HCN3 CNGB1

1.95e-04140765GO:0099094
GeneOntologyMolecularFunctionglycerophosphodiester phosphodiesterase activity

GDPD4 GDE1

2.12e-046762GO:0008889
GeneOntologyMolecularFunctionintracellularly ligand-gated monoatomic ion channel activity

HCN4 HCN3 CNGB1

2.66e-0433763GO:0005217
GeneOntologyMolecularFunctioncalcium ion transmembrane transporter activity

GPM6A TMC1 TRPV3 CACNA1G CNGB1

2.78e-04151765GO:0015085
GeneOntologyMolecularFunctioncytokine binding

BMPR1A BMPR1B CCRL2 ACVR2B NRP2

3.32e-04157765GO:0019955
GeneOntologyMolecularFunction3-hydroxyacyl-CoA dehydratase activity

HACD3 HACD1

3.94e-048762GO:0018812
GeneOntologyMolecularFunctioncyclic nucleotide binding

HCN4 HCN3 CNGB1

4.39e-0439763GO:0030551
GeneOntologyMolecularFunctionpotassium ion transmembrane transporter activity

SLC9C1 HCN4 KCNJ4 KCNJ6 HCN3

4.41e-04167765GO:0015079
GeneOntologyMolecularFunctionactivin receptor activity

ACVR2A ACVR2B

5.06e-049762GO:0017002
GeneOntologyMolecularFunctionphosphoric diester hydrolase activity

GDPD4 PDE1A PLCD4 GDE1

5.14e-0497764GO:0008081
GeneOntologyMolecularFunctionG-protein alpha-subunit binding

KCNJ6 PLCD4 ADGRV1

5.86e-0443763GO:0001965
GeneOntologyMolecularFunctionvoltage-gated potassium channel activity

HCN4 KCNJ4 KCNJ6 HCN3

6.21e-04102764GO:0005249
GeneOntologyMolecularFunctionenoyl-CoA hydratase activity

HACD3 HACD1

9.21e-0412762GO:0004300
GeneOntologyMolecularFunctionactivin binding

ACVR2A ACVR2B

9.21e-0412762GO:0048185
GeneOntologyMolecularFunctiontransforming growth factor beta receptor activity

BMPR1A BMPR1B

1.09e-0313762GO:0005024
GeneOntologyMolecularFunctionpotassium channel activity

HCN4 KCNJ4 KCNJ6 HCN3

1.45e-03128764GO:0005267
GeneOntologyMolecularFunctionG protein-coupled receptor activity

OR4K2 OR13C8 OR1D5 CCRL2 ADGRF5 ADGRV1 OR1D4 GPR160 ADGRL3 OR1D2

1.86e-038847610GO:0004930
GeneOntologyMolecularFunctionmechanosensitive monoatomic ion channel activity

PIEZO2 TMC1

2.10e-0318762GO:0008381
GeneOntologyMolecularFunctiongrowth factor binding

SCN5A ACVR2A ACVR2B NRP2

2.97e-03156764GO:0019838
GeneOntologyMolecularFunctionBMP binding

BMPR1A BMPR1B

3.14e-0322762GO:0036122
GeneOntologyMolecularFunctioncarbon-oxygen lyase activity

HACD3 POLG HACD1

3.78e-0382763GO:0016835
GeneOntologyMolecularFunctionSMAD binding

BMPR1A BMPR1B USP9X

4.32e-0386763GO:0046332
GeneOntologyMolecularFunctioninward rectifier potassium channel activity

KCNJ4 KCNJ6

5.07e-0328762GO:0005242
GeneOntologyBiologicalProcessmonoatomic ion transmembrane transport

GPM6A SCN11A SLC9C1 PIEZO2 TMC1 PTPRC PSEN2 HCN4 ATP6AP2 KCNJ4 KCNJ6 SCN4A HCN3 SCN5A SCN7A SCN8A SLC39A6 COX15 TRPV3 CACNA1G CNGB1 SLC1A7 ATP10D LARGE1

5.54e-1311157524GO:0034220
GeneOntologyBiologicalProcessinorganic ion transmembrane transport

GPM6A SCN11A SLC9C1 TMC1 PTPRC PSEN2 HCN4 ATP6AP2 KCNJ4 KCNJ6 SCN4A HCN3 SCN5A SCN7A SCN8A SLC39A6 COX15 TRPV3 CACNA1G CNGB1 SLC1A7 RHAG LARGE1

6.93e-1310177523GO:0098660
GeneOntologyBiologicalProcessinorganic cation transmembrane transport

GPM6A SCN11A SLC9C1 TMC1 PTPRC PSEN2 HCN4 ATP6AP2 KCNJ4 KCNJ6 SCN4A HCN3 SCN5A SCN7A SCN8A SLC39A6 COX15 TRPV3 CACNA1G CNGB1 RHAG LARGE1

8.59e-139227522GO:0098662
GeneOntologyBiologicalProcessmonoatomic cation transport

GPM6A SCN11A SLC9C1 PIEZO2 TMC1 PTPRC PSEN2 HCN4 ATP6AP2 KCNJ4 KCNJ6 SCN4A HCN3 SCN5A SCN7A SCN8A SLC39A6 COX15 TRPV3 CACNA1G FLVCR2 CNGB1 ATP10D LARGE1

1.22e-1211577524GO:0006812
GeneOntologyBiologicalProcessmonoatomic cation transmembrane transport

GPM6A SCN11A SLC9C1 PIEZO2 TMC1 PTPRC PSEN2 HCN4 ATP6AP2 KCNJ4 KCNJ6 SCN4A HCN3 SCN5A SCN7A SCN8A SLC39A6 COX15 TRPV3 CACNA1G CNGB1 LARGE1

1.31e-129427522GO:0098655
GeneOntologyBiologicalProcessmonoatomic ion transport

GPM6A SCN11A SLC9C1 PIEZO2 TMC1 PTPRC PSEN2 HCN4 ATP6AP2 KCNJ4 KCNJ6 SCN4A HCN3 SCN5A SCN7A SCN8A SLC39A6 COX15 TRPV3 CACNA1G FLVCR2 CNGB1 SLC1A7 ATP10D LARGE1

6.47e-1213747525GO:0006811
GeneOntologyBiologicalProcessmetal ion transport

GPM6A SCN11A SLC9C1 TMC1 PTPRC PSEN2 HCN4 KCNJ4 KCNJ6 SCN4A HCN3 SCN5A SCN7A SCN8A SLC39A6 TRPV3 CACNA1G FLVCR2 CNGB1 LARGE1

2.71e-1010007520GO:0030001
GeneOntologyBiologicalProcessmembrane depolarization

SCN11A HCN4 SCN4A HCN3 SCN5A SCN8A CACNA1G ABCD1 CNGB1

5.52e-10121759GO:0051899
GeneOntologyBiologicalProcessmembrane depolarization during action potential

SCN11A HCN4 SCN4A SCN5A SCN8A CACNA1G

3.37e-0936756GO:0086010
GeneOntologyBiologicalProcesssodium ion transmembrane transport

SCN11A SLC9C1 HCN4 SCN4A HCN3 SCN5A SCN7A SCN8A CACNA1G CNGB1

4.10e-092087510GO:0035725
GeneOntologyBiologicalProcesscardiac muscle cell action potential

SCN11A HCN4 SCN4A SCN5A SCN7A SCN8A CACNA1G

2.92e-0887757GO:0086001
GeneOntologyBiologicalProcesscardiac muscle cell contraction

SCN11A HCN4 SCN4A SCN5A SCN7A SCN8A CACNA1G

4.66e-0893757GO:0086003
GeneOntologyBiologicalProcessinorganic ion import across plasma membrane

SLC9C1 HCN4 KCNJ4 KCNJ6 SCN5A SLC39A6 TRPV3 CACNA1G

4.73e-08142758GO:0099587
GeneOntologyBiologicalProcessinorganic cation import across plasma membrane

SLC9C1 HCN4 KCNJ4 KCNJ6 SCN5A SLC39A6 TRPV3 CACNA1G

4.73e-08142758GO:0098659
GeneOntologyBiologicalProcesssodium ion transport

SCN11A SLC9C1 HCN4 SCN4A HCN3 SCN5A SCN7A SCN8A CACNA1G CNGB1

5.83e-082757510GO:0006814
GeneOntologyBiologicalProcessstriated muscle contraction

SCN11A PSEN2 HCN4 SCN4A SCN5A SCN7A SCN8A CACNA1G LARGE1

9.21e-08217759GO:0006941
GeneOntologyBiologicalProcesscardiac muscle cell action potential involved in contraction

SCN11A SCN4A SCN5A SCN7A SCN8A CACNA1G

9.86e-0862756GO:0086002
GeneOntologyBiologicalProcessregulation of membrane potential

SCN11A PIEZO2 HCN4 KCNJ6 SCN4A HCN3 SCN5A SCN7A SCN8A CACNA1G ABCD1 CNGB1 SLC1A7

1.01e-075597513GO:0042391
GeneOntologyBiologicalProcesscardiac muscle contraction

SCN11A PSEN2 HCN4 SCN4A SCN5A SCN7A SCN8A CACNA1G

1.66e-07167758GO:0060048
GeneOntologyBiologicalProcessactin-mediated cell contraction

SCN11A HCN4 SCN4A SCN5A SCN7A SCN8A CACNA1G

3.98e-07127757GO:0070252
GeneOntologyBiologicalProcessmembrane depolarization during SA node cell action potential

HCN4 SCN5A CACNA1G

4.59e-075753GO:0086046
GeneOntologyBiologicalProcesspositive regulation of bone mineralization

BMPR1A BMPR1B ADGRV1 ACVR2A ACVR2B

9.35e-0749755GO:0030501
GeneOntologyBiologicalProcessactin filament-based movement

SCN11A HCN4 SCN4A SCN5A SCN7A SCN8A CACNA1G

1.40e-06153757GO:0030048
GeneOntologyBiologicalProcessimport across plasma membrane

SLC9C1 HCN4 KCNJ4 KCNJ6 SCN5A SLC39A6 TRPV3 CACNA1G

1.88e-06230758GO:0098739
GeneOntologyBiologicalProcesspositive regulation of biomineral tissue development

BMPR1A BMPR1B ADGRV1 ACVR2A ACVR2B

2.59e-0660755GO:0070169
GeneOntologyBiologicalProcessregulation of membrane depolarization

HCN4 HCN3 SCN5A CACNA1G ABCD1

2.82e-0661755GO:0003254
GeneOntologyBiologicalProcessneuronal action potential

SCN11A SCN4A SCN5A SCN8A CACNA1G

3.31e-0663755GO:0019228
GeneOntologyBiologicalProcesspositive regulation of ossification

BMPR1A BMPR1B ADGRV1 ACVR2A ACVR2B

4.17e-0666755GO:0045778
GeneOntologyBiologicalProcessSA node cell to atrial cardiac muscle cell signaling

HCN4 SCN5A CACNA1G

5.44e-0610753GO:0086018
GeneOntologyBiologicalProcessSA node cell action potential

HCN4 SCN5A CACNA1G

5.44e-0610753GO:0086015
GeneOntologyBiologicalProcesspotassium ion transport

SLC9C1 HCN4 KCNJ4 KCNJ6 SCN4A HCN3 CNGB1 LARGE1

6.49e-06272758GO:0006813
GeneOntologyBiologicalProcessSA node cell to atrial cardiac muscle cell communication

HCN4 SCN5A CACNA1G

7.46e-0611753GO:0086070
GeneOntologyBiologicalProcessaction potential

SCN11A HCN4 SCN4A SCN5A SCN7A SCN8A CACNA1G

8.52e-06201757GO:0001508
GeneOntologyBiologicalProcessheart contraction

SCN11A PSEN2 HCN4 SCN4A SCN5A SCN7A SCN8A CACNA1G

1.26e-05298758GO:0060047
GeneOntologyBiologicalProcesscardiac conduction system development

BMPR1A HCN4 SCN5A CACNA1G

1.33e-0540754GO:0003161
GeneOntologyBiologicalProcessmuscle contraction

SCN11A PSEN2 HCN4 SCN4A SCN5A SCN7A SCN8A CACNA1G LARGE1

1.44e-05400759GO:0006936
GeneOntologyBiologicalProcessheart process

SCN11A PSEN2 HCN4 SCN4A SCN5A SCN7A SCN8A CACNA1G

1.64e-05309758GO:0003015
GeneOntologyBiologicalProcessregulation of bone mineralization

BMPR1A BMPR1B ADGRV1 ACVR2A ACVR2B

2.02e-0591755GO:0030500
GeneOntologyBiologicalProcessfatty acid elongation

HACD3 ABCD1 HACD1

2.04e-0515753GO:0030497
GeneOntologyBiologicalProcesssensory perception of mechanical stimulus

SCN11A PIEZO2 TMC1 SCN8A ADGRV1 USH2A LARGE1

2.54e-05238757GO:0050954
GeneOntologyBiologicalProcessdetection of stimulus involved in sensory perception

SCN11A PIEZO2 OR4K2 TMC1 OR13C8 OR1D5 ADGRV1 OR1D4 CNGB1 OR1D2

4.72e-055827510GO:0050906
GeneOntologyBiologicalProcesstransmission of nerve impulse

SCN11A SCN4A SCN5A SCN8A CACNA1G

5.50e-05112755GO:0019226
GeneOntologyBiologicalProcessdetection of mechanical stimulus involved in sensory perception

SCN11A PIEZO2 TMC1 ADGRV1

5.50e-0557754GO:0050974
GeneOntologyBiologicalProcessanatomical structure arrangement

BMPR1A USP9X NRP2

5.86e-0521753GO:0048532
GeneOntologyBiologicalProcessregulation of biomineral tissue development

BMPR1A BMPR1B ADGRV1 ACVR2A ACVR2B

5.99e-05114755GO:0070167
GeneOntologyBiologicalProcesssphingolipid biosynthetic process

ACER1 HACD3 UGCG HACD1 LARGE1

6.78e-05117755GO:0030148
GeneOntologyBiologicalProcessmembrane depolarization during cardiac muscle cell action potential

HCN4 SCN5A CACNA1G

7.76e-0523753GO:0086012
GeneOntologyBiologicalProcesscalcium ion transmembrane transport

GPM6A SCN11A TMC1 PTPRC PSEN2 TRPV3 CACNA1G CNGB1

8.80e-05392758GO:0070588
GeneOntologyBiologicalProcessbiomineral tissue development

BMPR1A BMPR1B ADGRV1 ACVR2A ACVR2B HACD1

9.66e-05203756GO:0031214
GeneOntologyBiologicalProcesssensory perception

SCN11A PIEZO2 OR4K2 TMC1 OR13C8 SCN8A OR1D5 ADGRV1 USH2A OR1D4 CNGB1 OR1D2 LARGE1

1.18e-0410727513GO:0007600
GeneOntologyBiologicalProcesssodium ion import across plasma membrane

SLC9C1 HCN4 SCN5A

1.27e-0427753GO:0098719
GeneOntologyBiologicalProcessmaintenance of animal organ identity

ADGRV1 USH2A

1.30e-045752GO:0048496
GeneOntologyBiologicalProcessmuscle system process

SCN11A PSEN2 HCN4 SCN4A SCN5A SCN7A SCN8A CACNA1G LARGE1

1.61e-04547759GO:0003012
GeneOntologyBiologicalProcessdetection of mechanical stimulus

SCN11A PIEZO2 TMC1 ADGRV1

1.61e-0475754GO:0050982
GeneOntologyBiologicalProcessmembrane depolarization during AV node cell action potential

SCN5A CACNA1G

1.94e-046752GO:0086045
GeneOntologyBiologicalProcessregulation of ossification

BMPR1A BMPR1B ADGRV1 ACVR2A ACVR2B

1.98e-04147755GO:0030278
GeneOntologyBiologicalProcesspotassium ion transmembrane transport

SLC9C1 HCN4 KCNJ4 KCNJ6 HCN3 LARGE1

2.00e-04232756GO:0071805
GeneOntologyBiologicalProcessbone mineralization

BMPR1A BMPR1B ADGRV1 ACVR2A ACVR2B

2.11e-04149755GO:0030282
GeneOntologyBiologicalProcessodontogenesis

BMPR1A SCN5A ACVR2A ACVR2B HACD1

2.25e-04151755GO:0042476
GeneOntologyBiologicalProcesscell-cell signaling involved in cardiac conduction

HCN4 SCN5A CACNA1G

2.55e-0434753GO:0086019
GeneOntologyBiologicalProcessmembrane lipid biosynthetic process

ACER1 HACD3 UGCG HACD1 LARGE1

2.69e-04157755GO:0046467
GeneOntologyBiologicalProcessdetection of stimulus

SCN11A PIEZO2 OR4K2 TMC1 OR13C8 OR1D5 ADGRV1 OR1D4 CNGB1 OR1D2

2.76e-047227510GO:0051606
GeneOntologyBiologicalProcessvery long-chain fatty acid metabolic process

HACD3 ABCD1 HACD1

2.78e-0435753GO:0000038
GeneOntologyBiologicalProcesspositive regulation of osteoblast differentiation

BMPR1A BMPR1B ACVR2A ACVR2B

2.98e-0488754GO:0045669
GeneOntologyBiologicalProcesspositive regulation of activin receptor signaling pathway

ACVR2A ACVR2B

3.60e-048752GO:0032927
GeneOntologyBiologicalProcessperoxisome organization

USP9X ABCD1 MFF

3.84e-0439753GO:0007031
GeneOntologyBiologicalProcessdetection of external stimulus

SCN11A PIEZO2 TMC1 ADGRV1 CNGB1

4.21e-04173755GO:0009581
GeneOntologyBiologicalProcessdetection of abiotic stimulus

SCN11A PIEZO2 TMC1 ADGRV1 CNGB1

4.44e-04175755GO:0009582
GeneOntologyBiologicalProcessregulation of heart rate by cardiac conduction

HCN4 SCN5A CACNA1G

4.46e-0441753GO:0086091
GeneOntologyBiologicalProcesssphingolipid metabolic process

ACER1 HACD3 UGCG HACD1 LARGE1

4.55e-04176755GO:0006665
GeneOntologyBiologicalProcessimport into cell

NPC1 SLC9C1 PTPRC HCN4 KCNJ4 KCNJ6 SCN5A SLC39A6 TRPV3 CACNA1G SLC1A7 MFF

4.68e-0410747512GO:0098657
GeneOntologyBiologicalProcesscalcium ion transport

GPM6A SCN11A TMC1 PTPRC PSEN2 TRPV3 CACNA1G CNGB1

5.15e-04509758GO:0006816
GeneOntologyBiologicalProcessblood circulation

SCN11A PSEN2 HCN4 ATP6AP2 SCN4A SCN5A SCN7A SCN8A CACNA1G

5.58e-04648759GO:0008015
GeneOntologyBiologicalProcessregulation of atrial cardiac muscle cell membrane depolarization

SCN5A CACNA1G

5.76e-0410752GO:0060371
GeneOntologyBiologicalProcessodontogenesis of dentin-containing tooth

BMPR1A SCN5A ACVR2A ACVR2B

6.27e-04107754GO:0042475
GeneOntologyBiologicalProcessphotoreceptor cell maintenance

ADGRV1 USH2A CNGB1

6.67e-0447753GO:0045494
GeneOntologyBiologicalProcessnerve development

SCN8A CNGB1 NRP2 LARGE1

6.72e-04109754GO:0021675
GeneOntologyBiologicalProcessprotein kinase A signaling

SCN11A MROH2B ADGRV1

7.10e-0448753GO:0010737
GeneOntologyBiologicalProcessBMP signaling pathway

BMPR1A BMPR1B USP9X ACVR2A ACVR2B

7.59e-04197755GO:0030509
GeneOntologyBiologicalProcesssensory perception of sound

TMC1 SCN8A ADGRV1 USH2A LARGE1

7.76e-04198755GO:0007605
GeneOntologyBiologicalProcessAV node cell to bundle of His cell signaling

SCN5A CACNA1G

8.41e-0412752GO:0086027
GeneOntologyBiologicalProcessAV node cell action potential

SCN5A CACNA1G

8.41e-0412752GO:0086016
GeneOntologyBiologicalProcesspotassium ion import across plasma membrane

HCN4 KCNJ4 KCNJ6

8.48e-0451753GO:1990573
GeneOntologyBiologicalProcesssinoatrial node development

HCN4 CACNA1G

9.92e-0413752GO:0003163
GeneOntologyBiologicalProcessvery long-chain fatty acid biosynthetic process

HACD3 HACD1

9.92e-0413752GO:0042761
GeneOntologyBiologicalProcesspharyngeal arch artery morphogenesis

BMPR1A ADGRF5

9.92e-0413752GO:0061626
GeneOntologyBiologicalProcessresponse to BMP

BMPR1A BMPR1B USP9X ACVR2A ACVR2B

1.12e-03215755GO:0071772
GeneOntologyBiologicalProcesscellular response to BMP stimulus

BMPR1A BMPR1B USP9X ACVR2A ACVR2B

1.12e-03215755GO:0071773
GeneOntologyBiologicalProcesspositive regulation of extrinsic apoptotic signaling pathway via death domain receptors

BMPR1B PSEN2

1.15e-0314752GO:1902043
GeneOntologyBiologicalProcessneuron migration

GPM6A USP9X ADGRL3 NRP2 LARGE1

1.19e-03218755GO:0001764
GeneOntologyBiologicalProcesscell communication involved in cardiac conduction

HCN4 SCN5A CACNA1G

1.30e-0359753GO:0086065
GeneOntologyBiologicalProcessAV node cell to bundle of His cell communication

SCN5A CACNA1G

1.33e-0315752GO:0086067
GeneOntologyBiologicalProcesscirculatory system process

SCN11A PSEN2 HCN4 ATP6AP2 SCN4A SCN5A SCN7A SCN8A CACNA1G

1.33e-03733759GO:0003013
GeneOntologyBiologicalProcesswalking behavior

NPC1 SCN8A LARGE1

1.36e-0360753GO:0090659
GeneOntologyBiologicalProcessartery development

SCN11A BMPR1A ADGRF5 ACVR2B

1.41e-03133754GO:0060840
GeneOntologyBiologicalProcessG protein-coupled receptor signaling pathway

SCN11A OR4K2 OR13C8 OR1D5 CCRL2 ADGRF5 ADGRV1 OR1D4 CNGB1 GPR160 ADGRL3 GDE1 OR1D2

1.45e-0313957513GO:0007186
GeneOntologyBiologicalProcessmembrane lipid metabolic process

ACER1 HACD3 UGCG HACD1 LARGE1

1.48e-03229755GO:0006643
GeneOntologyBiologicalProcesspositive regulation of extrinsic apoptotic signaling pathway

BMPR1B PTPRC PSEN2

1.57e-0363753GO:2001238
GeneOntologyBiologicalProcessretina homeostasis

ADGRV1 USH2A CNGB1

1.64e-0364753GO:0001895
GeneOntologyBiologicalProcessregionalization

BMPR1A BMPR1B PSEN2 ATP6AP2 ACVR2A ACVR2B NRP2

1.75e-03478757GO:0003002
GeneOntologyCellularComponentvoltage-gated sodium channel complex

SCN11A SCN4A SCN5A SCN7A SCN8A CACNA1G

2.45e-1117776GO:0001518
GeneOntologyCellularComponentsodium channel complex

SCN11A SCN4A SCN5A SCN7A SCN8A CACNA1G

9.09e-1029776GO:0034706
GeneOntologyCellularComponentcation channel complex

SCN11A HCN4 KCNJ4 KCNJ6 SCN4A HCN3 SCN5A SCN7A SCN8A CACNA1G CNGB1

9.98e-102357711GO:0034703
GeneOntologyCellularComponentaxon

GPM6A AMFR SCN11A HCN4 ATP6AP2 USP9X KCNJ6 POLG SCN4A HCN3 SCN5A SCN8A UNC13C USH2A CNGB1 SLC1A7 ADGRL3 NRP2

2.77e-098917718GO:0030424
GeneOntologyCellularComponentmembrane protein complex

AMFR SCN11A BMPR1A BMPR1B PSEN2 HCN4 SLC38A9 CLMN ATP6AP2 KCNJ4 KCNJ6 SCN4A HCN3 SCN5A SCN7A SCN8A COX15 CACNA1G ACVR2A ACVR2B CNGB1 RHAG

1.24e-0814987722GO:0098796
GeneOntologyCellularComponenttransporter complex

SCN11A HCN4 ATP6AP2 KCNJ4 KCNJ6 SCN4A HCN3 SCN5A SCN7A SCN8A CACNA1G CNGB1 ATP10D

9.91e-085507713GO:1990351
GeneOntologyCellularComponentmonoatomic ion channel complex

SCN11A HCN4 KCNJ4 KCNJ6 SCN4A HCN3 SCN5A SCN7A SCN8A CACNA1G CNGB1

1.34e-073787711GO:0034702
GeneOntologyCellularComponentplasma membrane protein complex

SCN11A BMPR1A BMPR1B PSEN2 HCN4 KCNJ4 KCNJ6 SCN4A HCN3 SCN5A SCN7A SCN8A CACNA1G ACVR2A ACVR2B

1.47e-077857715GO:0098797
GeneOntologyCellularComponenttransmembrane transporter complex

SCN11A HCN4 ATP6AP2 KCNJ4 KCNJ6 SCN4A HCN3 SCN5A SCN7A SCN8A CACNA1G CNGB1

4.45e-075237712GO:1902495
GeneOntologyCellularComponentdistal axon

GPM6A AMFR SCN11A HCN4 USP9X POLG HCN3 UNC13C USH2A CNGB1 SLC1A7

5.43e-074357711GO:0150034
GeneOntologyCellularComponentpresynapse

GPM6A SCN11A PSEN2 HCN4 ATP6AP2 KCNJ6 POLG HCN3 SCN8A RTN3 UNC13C USH2A CNGB1 SLC1A7 MFF

6.87e-078867715GO:0098793
GeneOntologyCellularComponentcell body

GPM6A AMFR SCN11A PDE1A BMPR1A BMPR1B PSEN2 HCN4 ATP6AP2 KCNJ4 KCNJ6 HCN3 SCN8A CACNA1G USH2A

1.24e-069297715GO:0044297
GeneOntologyCellularComponentterminal bouton

HCN4 POLG UNC13C USH2A CNGB1 SLC1A7

1.46e-0696776GO:0043195
GeneOntologyCellularComponentneuronal cell body

GPM6A AMFR SCN11A PDE1A BMPR1A BMPR1B PSEN2 HCN4 KCNJ4 KCNJ6 HCN3 SCN8A CACNA1G USH2A

1.91e-068357714GO:0043025
GeneOntologyCellularComponentsynaptic membrane

GPM6A SCN11A PSEN2 ATP6AP2 KCNJ4 KCNJ6 SCN8A UNC13C SLC1A7 ADGRL3 NRP2

9.11e-065837711GO:0097060
GeneOntologyCellularComponentaxon terminus

HCN4 POLG HCN3 UNC13C USH2A CNGB1 SLC1A7

1.24e-05210777GO:0043679
GeneOntologyCellularComponentparallel fiber to Purkinje cell synapse

GPM6A KCNJ6 SCN8A UNC13C

1.88e-0543774GO:0098688
GeneOntologyCellularComponentneuron projection terminus

HCN4 POLG HCN3 UNC13C USH2A CNGB1 SLC1A7

2.42e-05233777GO:0044306
GeneOntologyCellularComponentsomatodendritic compartment

GPM6A AMFR SCN11A PDE1A BMPR1A BMPR1B PSEN2 HCN4 ATP6AP2 KCNJ4 KCNJ6 HCN3 SCN8A CACNA1G USH2A

3.55e-0512287715GO:0036477
GeneOntologyCellularComponentpresynaptic membrane

GPM6A SCN11A PSEN2 KCNJ6 SCN8A UNC13C SLC1A7

7.25e-05277777GO:0042734
GeneOntologyCellularComponentHCN channel complex

HCN4 HCN3

8.00e-054772GO:0098855
GeneOntologyCellularComponentUSH2 complex

ADGRV1 USH2A

8.00e-054772GO:1990696
GeneOntologyCellularComponentstereocilia ankle link

ADGRV1 USH2A

1.99e-046772GO:0002141
GeneOntologyCellularComponentstereocilia ankle link complex

ADGRV1 USH2A

1.99e-046772GO:0002142
GeneOntologyCellularComponentactivin receptor complex

ACVR2A ACVR2B

1.99e-046772GO:0048179
GeneOntologyCellularComponentstereocilium membrane

ADGRV1 USH2A

1.99e-046772GO:0060171
GeneOntologyCellularComponentpericiliary membrane compartment

ADGRV1 USH2A

1.99e-046772GO:1990075
GeneOntologyCellularComponentdendrite

GPM6A AMFR BMPR1A BMPR1B HCN4 ATP6AP2 KCNJ4 KCNJ6 HCN3 SCN8A CACNA1G

2.94e-048587711GO:0030425
GeneOntologyCellularComponentdendritic tree

GPM6A AMFR BMPR1A BMPR1B HCN4 ATP6AP2 KCNJ4 KCNJ6 HCN3 SCN8A CACNA1G

2.99e-048607711GO:0097447
GeneOntologyCellularComponentvoltage-gated potassium channel complex

HCN4 KCNJ4 KCNJ6 HCN3

3.57e-0491774GO:0008076
GeneOntologyCellularComponentstereocilia coupling link

ADGRV1 USH2A

3.70e-048772GO:0002139
GeneOntologyCellularComponentHFE-transferrin receptor complex

BMPR1A BMPR1B

3.70e-048772GO:1990712
GeneOntologyCellularComponentpotassium channel complex

HCN4 KCNJ4 KCNJ6 HCN3

5.92e-04104774GO:0034705
GeneOntologyCellularComponentexcitatory synapse

GPM6A KCNJ6 SCN8A UNC13C

6.59e-04107774GO:0060076
GeneOntologyCellularComponentcell surface

BMPR1A TMC1 PTPRC ATP6AP2 KCNJ6 SCN5A CD274 SLC39A6 CCRL2 ADGRF5 ADGRV1 ACVR2A

7.17e-0411117712GO:0009986
GeneOntologyCellularComponentnuclear outer membrane-endoplasmic reticulum membrane network

AMFR ACER1 PSEN2 HACD3 CLMN ATP6AP2 ZDHHC22 RTN3 PLCD4 ABCD1 FLVCR2 HACD1 ATP10D

1.05e-0313277713GO:0042175
GeneOntologyCellularComponentreceptor complex

BMPR1A BMPR1B TRPV3 ADGRV1 ACVR2A ACVR2B GPR160 NRP2

1.33e-03581778GO:0043235
GeneOntologyCellularComponentstereocilium

TMC1 ADGRV1 USH2A

2.11e-0369773GO:0032420
GeneOntologyCellularComponentendoplasmic reticulum membrane

AMFR ACER1 PSEN2 HACD3 ATP6AP2 ZDHHC22 RTN3 PLCD4 ABCD1 FLVCR2 HACD1 ATP10D

2.61e-0312937712GO:0005789
GeneOntologyCellularComponentendoplasmic reticulum subcompartment

AMFR ACER1 PSEN2 HACD3 ATP6AP2 ZDHHC22 RTN3 PLCD4 ABCD1 FLVCR2 HACD1 ATP10D

2.71e-0312997712GO:0098827
GeneOntologyCellularComponentglutamatergic synapse

GPM6A SCN11A PSEN2 KCNJ4 SCN8A RTN3 SLC1A7 ADGRL3 NRP2

3.05e-03817779GO:0098978
GeneOntologyCellularComponentstereocilium bundle

TMC1 ADGRV1 USH2A

3.11e-0379773GO:0032421
GeneOntologyCellularComponentneuron projection membrane

ATP6AP2 ADGRV1 USH2A

3.45e-0382773GO:0032589
GeneOntologyCellularComponentpostsynaptic membrane

ATP6AP2 KCNJ4 SCN8A SLC1A7 ADGRL3 NRP2

3.80e-03405776GO:0045211
GeneOntologyCellularComponentpostsynapse

GPM6A ATP6AP2 USP9X KCNJ4 KCNJ6 SCN8A RTN3 SLC1A7 ADGRL3 NRP2

4.07e-0310187710GO:0098794
GeneOntologyCellularComponentcell projection membrane

SLC9C1 ATP6AP2 SLC39A6 ADGRV1 USH2A CNGB1

5.13e-03431776GO:0031253
GeneOntologyCellularComponentleading edge membrane

ATP6AP2 SLC39A6 ADGRV1 USH2A

7.56e-03210774GO:0031256
GeneOntologyCellularComponentcytoplasmic vesicle membrane

NPC1 PTPRC SLC38A9 ATP6AP2 KCNJ4 CD274 UNC13C SCAMP2 CNGB1 MFF GDE1

8.17e-0313077711GO:0030659
GeneOntologyCellularComponentvesicle membrane

NPC1 PTPRC SLC38A9 ATP6AP2 KCNJ4 CD274 UNC13C SCAMP2 CNGB1 MFF GDE1

9.01e-0313257711GO:0012506
HumanPhenoAplasia/Hypoplasia involving the skeletal musculature

PIEZO2 SCN4A FLVCR2 HACD1 LARGE1

1.58e-0551335HP:0001460
HumanPhenoApneic episodes in infancy

SCN4A SCN5A HACD1

2.88e-0510333HP:0005949
HumanPhenoAstereognosis

ATP6AP2 ABCD1

4.07e-052332HP:0010527
HumanPhenoTactile agnosia

ATP6AP2 ABCD1

4.07e-052332HP:5200406
HumanPhenoMask-like facies

PIEZO2 ATP6AP2 KCNJ6 POLG HACD1 LARGE1

5.79e-05109336HP:0000298
HumanPhenoDisturbed perception with a stimulus

BMPR1A PSEN2 ATP6AP2 ABCD1

7.43e-0536334HP:5200204
HumanPhenoDisturbed sensory perception

BMPR1A PSEN2 ATP6AP2 ABCD1

7.43e-0536334HP:0010524
HumanPhenoAbnormal interpretation of external stimuli

BMPR1A PSEN2 ATP6AP2 ABCD1

8.30e-0537334HP:5200202
MousePhenoabnormal action potential

SCN11A HCN3 SCN5A TSPAN7 SCN8A CACNA1G CNGB1

1.92e-06133627MP:0005402
MousePhenoabnormal nervous system electrophysiology

SCN11A HCN4 HCN3 SCN5A TSPAN7 SCN8A CACNA1G ABCD1 CNGB1

1.34e-05329629MP:0002272
DomainIon_trans_dom

SCN11A SLC9C1 HCN4 SCN4A HCN3 SCN5A SCN7A SCN8A TRPV3 CACNA1G CNGB1

1.28e-121147711IPR005821
DomainIon_trans

SCN11A SLC9C1 HCN4 SCN4A HCN3 SCN5A SCN7A SCN8A TRPV3 CACNA1G CNGB1

1.28e-121147711PF00520
DomainNa_channel_asu

SCN11A SCN4A SCN5A SCN7A SCN8A

2.59e-1010775IPR001696
DomainNa_trans_assoc

SCN11A SCN4A SCN5A SCN7A SCN8A

2.59e-1010775IPR010526
DomainNa_trans_assoc

SCN11A SCN4A SCN5A SCN7A SCN8A

2.59e-1010775PF06512
DomainActivin_recp

BMPR1A BMPR1B ACVR2A ACVR2B

5.50e-0810774IPR000472
DomainActivin_recp

BMPR1A BMPR1B ACVR2A ACVR2B

5.50e-0810774PF01064
DomainChannel_four-helix_dom

SCN11A SCN4A SCN5A SCN7A SCN8A CACNA1G

1.24e-0757776IPR027359
Domain-

SCN11A SCN4A SCN5A SCN7A SCN8A CACNA1G

1.24e-07577761.20.120.350
DomainTGFB_receptor

BMPR1A BMPR1B ACVR2A ACVR2B

1.29e-0712774IPR000333
DomainCNMP_BINDING_1

SLC9C1 HCN4 HCN3 CNGB1

8.80e-0632774PS00888
DomainCNMP_BINDING_2

SLC9C1 HCN4 HCN3 CNGB1

8.80e-0632774PS00889
DomaincNMP

SLC9C1 HCN4 HCN3 CNGB1

1.13e-0534774SM00100
DomaincNMP_binding

SLC9C1 HCN4 HCN3 CNGB1

1.13e-0534774PF00027
DomaincNMP-bd_dom

SLC9C1 HCN4 HCN3 CNGB1

1.27e-0535774IPR000595
DomainCNMP_BINDING_3

SLC9C1 HCN4 HCN3 CNGB1

1.27e-0535774PS50042
DomaincNMP-bd-like

SLC9C1 HCN4 HCN3 CNGB1

1.77e-0538774IPR018490
Domain-

SLC9C1 HCN4 HCN3 CNGB1

4.53e-05487742.60.120.10
DomainRmlC-like_jellyroll

SLC9C1 HCN4 HCN3 CNGB1

5.76e-0551774IPR014710
DomainIon_trans_N

HCN4 HCN3

1.00e-044772PF08412
DomainIon_trans_N

HCN4 HCN3

1.00e-044772IPR013621
DomainTyr_Pase-like_PTPLA

HACD3 HACD1

1.00e-044772IPR007482
DomainPTPLA

HACD3 HACD1

1.00e-044772PF04387
Domain-

GDPD4 PLCD4 GDE1

1.45e-04257733.20.20.190
DomainPLC-like_Pdiesterase_TIM-brl

GDPD4 PLCD4 GDE1

1.45e-0425773IPR017946
DomainNa_trans_cytopl

SCN5A SCN8A

2.49e-046772PF11933
DomainNa_trans_cytopl

SCN5A SCN8A

2.49e-046772IPR024583
DomainGS

BMPR1A BMPR1B

3.48e-047772SM00467
DomainGS_dom

BMPR1A BMPR1B

3.48e-047772IPR003605
DomainGP_PDE_dom

GDPD4 GDE1

3.48e-047772IPR030395
DomainGS

BMPR1A BMPR1B

3.48e-047772PS51256
DomainGlyceroP-diester-Pdiesterase

GDPD4 GDE1

3.48e-047772IPR004129
DomainTGF_beta_GS

BMPR1A BMPR1B

3.48e-047772PF08515
DomainGP_PDE

GDPD4 GDE1

3.48e-047772PS51704
DomainGDPD

GDPD4 GDE1

3.48e-047772PF03009
DomainIQ

SCN4A SCN5A SCN7A SCN8A

3.49e-0481774SM00015
DomainGPS

ADGRF5 ADGRV1 ADGRL3

3.68e-0434773SM00303
DomainGPS

ADGRF5 ADGRV1 ADGRL3

4.01e-0435773PF01825
DomainGPS

ADGRF5 ADGRV1 ADGRL3

4.36e-0436773PS50221
DomainGPS

ADGRF5 ADGRV1 ADGRL3

4.73e-0437773IPR000203
DomainIQ_motif_EF-hand-BS

SCN4A SCN5A SCN7A SCN8A

5.22e-0490774IPR000048
DomainG_PROTEIN_RECEP_F2_1

ADGRF5 ADGRV1 ADGRL3

5.96e-0440773PS00649
DomainGPCR_2_extracellular_dom

ADGRF5 ADGRV1 ADGRL3

5.96e-0440773IPR001879
DomainG_PROTEIN_RECEP_F2_3

ADGRF5 ADGRV1 ADGRL3

5.96e-0440773PS50227
DomainG_PROTEIN_RECEP_F2_2

ADGRF5 ADGRV1 ADGRL3

1.15e-0350773PS00650
Domain7tm_2

ADGRF5 ADGRV1 ADGRL3

1.15e-0350773PF00002
DomainSSD

NPC1 ZDHHC22

1.27e-0313772IPR000731
DomainSSD

NPC1 ZDHHC22

1.27e-0313772PS50156
DomainK_chnl_volt-dep_EAG/ELK/ERG

HCN4 HCN3

1.48e-0314772IPR003938
DomainK_chnl_inward-rec_Kir_cyto

KCNJ4 KCNJ6

1.94e-0316772IPR013518
DomaincNMP-bd_CS

HCN4 CNGB1

1.94e-0316772IPR018488
DomainIRK

KCNJ4 KCNJ6

1.94e-0316772PF01007
Domain-

KCNJ4 KCNJ6

1.94e-03167722.60.40.1400
DomainK_chnl_inward-rec_Kir

KCNJ4 KCNJ6

1.94e-0316772IPR016449
DomainGPCR_2_secretin-like

ADGRF5 ADGRV1 ADGRL3

1.95e-0360773IPR000832
DomainGPCR_2-like

ADGRF5 ADGRV1 ADGRL3

1.95e-0360773IPR017981
DomainG_PROTEIN_RECEP_F2_4

ADGRF5 ADGRV1 ADGRL3

2.04e-0361773PS50261
DomainTetraspanin_CS

TSPAN7 TSPAN6

3.35e-0321772IPR018503
DomainTM4_1

TSPAN7 TSPAN6

5.11e-0326772PS00421
DomainIQ

SCN4A SCN5A SCN8A

6.70e-0393773PS50096
DomainTetraspanin

TSPAN7 TSPAN6

7.68e-0332772IPR000301
PathwayREACTOME_INTERACTION_BETWEEN_L1_AND_ANKYRINS

SCN11A SCN4A SCN5A SCN7A SCN8A

2.36e-0731635M877
PathwayREACTOME_PHASE_0_RAPID_DEPOLARISATION

SCN11A SCN4A SCN5A SCN7A SCN8A

2.78e-0732635M27455
PathwayKEGG_MEDICUS_REFERENCE_BMP_SIGNALING_PATHWAY

BMPR1A BMPR1B ACVR2A ACVR2B

1.66e-0620634M47843
PathwayREACTOME_SIGNALING_BY_BMP

BMPR1A BMPR1B ACVR2A ACVR2B

1.04e-0531634M1662
PathwayREACTOME_SIGNALING_BY_BMP

BMPR1A BMPR1B ACVR2A ACVR2B

1.04e-0531634MM14789
PathwayREACTOME_L1CAM_INTERACTIONS

SCN11A SCN4A SCN5A SCN7A SCN8A NRP2

1.61e-05121636M872
PathwayREACTOME_CARDIAC_CONDUCTION

SCN11A KCNJ4 SCN4A SCN5A SCN7A SCN8A

2.42e-05130636M27454
PathwayREACTOME_MUSCLE_CONTRACTION

SCN11A KCNJ4 SCN4A SCN5A SCN7A SCN8A CACNA1G

3.24e-05203637M5485
PathwayREACTOME_SIGNALING_BY_TGFB_FAMILY_MEMBERS

BMPR1A BMPR1B PSEN2 USP9X ACVR2A ACVR2B

8.02e-05161636M27871
PathwayREACTOME_SIGNALING_BY_TGFB_FAMILY_MEMBERS

BMPR1A BMPR1B USP9X ACVR2A ACVR2B

1.80e-04118635MM15588
PathwayREACTOME_NERVOUS_SYSTEM_DEVELOPMENT

SCN11A PTPRC PSEN2 SCN4A SCN5A SCN7A SCN8A CACNA1G ADGRV1 NRP2

2.14e-045756310M29853
PathwayKEGG_MEDICUS_REFERENCE_BMP_HAMP_SIGNALING_PATHWAY_AUXILIARY_FACTOR

BMPR1A ACVR2B

4.07e-047632M47851
PathwayKEGG_MEDICUS_REFERENCE_NODAL_SIGNALING_PATHWAY

ACVR2A ACVR2B

5.41e-048632M47849
PathwayKEGG_MEDICUS_REFERENCE_ACTIVIN_SIGNALING_PATHWAY

ACVR2A ACVR2B

5.41e-048632M47846
PathwayKEGG_TGF_BETA_SIGNALING_PATHWAY

BMPR1A BMPR1B ACVR2A ACVR2B

5.85e-0486634M2642
PathwayKEGG_MEDICUS_REFERENCE_AMH_SIGNALING_PATHWAY

BMPR1A BMPR1B

6.93e-049632M47844
PathwayREACTOME_NEURONAL_SYSTEM

HCN4 KCNJ4 KCNJ6 HCN3 TSPAN7 RTN3 SLC1A7

7.10e-04335637MM14503
PathwayREACTOME_POTASSIUM_CHANNELS

HCN4 KCNJ4 KCNJ6 HCN3

9.56e-0498634MM14545
PathwayKEGG_MEDICUS_REFERENCE_BMP_HAMP_SIGNALING_PATHWAY

BMPR1A ACVR2B

1.05e-0311632M47848
PathwayREACTOME_POTASSIUM_CHANNELS

HCN4 KCNJ4 KCNJ6 HCN3

1.15e-03103634M1073
PathwayWP_BONE_MORPHOGENIC_PROTEIN_SIGNALING_AND_REGULATION

BMPR1A BMPR1B

1.26e-0312632M39519
PathwayREACTOME_REGULATION_OF_SIGNALING_BY_NODAL

ACVR2A ACVR2B

1.26e-0312632M26952
Pubmed

Large-scale analysis of ion channel gene expression in the mouse heart during perinatal development.

SCN11A HCN4 KCNJ4 KCNJ6 SCN4A HCN3 SCN5A SCN7A SCN8A CACNA1G

6.54e-13139771016985003
Pubmed

DRAGON, a bone morphogenetic protein co-receptor.

BMPR1A BMPR1B ACVR2A ACVR2B

1.54e-09877415671031
Pubmed

Identification of type I and type II serine/threonine kinase receptors for growth/differentiation factor-5.

BMPR1A BMPR1B ACVR2A ACVR2B

1.54e-0987748702914
Pubmed

Characterization of bone morphogenetic protein-6 signaling pathways in osteoblast differentiation.

BMPR1A BMPR1B ACVR2A ACVR2B

1.54e-09877410504300
Pubmed

Mutant GDF5 enhances ameloblast differentiation via accelerated BMP2-induced Smad1/5/8 phosphorylation.

BMPR1A BMPR1B ACVR2A ACVR2B

2.77e-09977427030100
Pubmed

International Union of Pharmacology. XLVII. Nomenclature and structure-function relationships of voltage-gated sodium channels.

SCN11A SCN4A SCN5A SCN8A

2.77e-09977416382098
Pubmed

Human retroviral gag- and gag-pol-like proteins interact with the transforming growth factor-beta receptor activin receptor-like kinase 1.

BMPR1A BMPR1B ACVR2A ACVR2B

4.62e-091077415611116
Pubmed

BMP-2/4 and BMP-6/7 differentially utilize cell surface receptors to induce osteoblastic differentiation of human bone marrow-derived mesenchymal stem cells.

BMPR1A BMPR1B ACVR2A ACVR2B

4.62e-091077418436533
Pubmed

Modulation of activin signal transduction by inhibin B and inhibin-binding protein (INhBP).

BMPR1A BMPR1B ACVR2A ACVR2B

4.62e-091077411266516
Pubmed

Endofin acts as a Smad anchor for receptor activation in BMP signaling.

BMPR1A BMPR1B ACVR2A ACVR2B

7.24e-091177417356069
Pubmed

Convergence of bone morphogenetic protein and laminin-1 signaling pathways promotes proliferation and colony formation by fetal mouse pancreatic cells.

BMPR1A BMPR1B ACVR2A ACVR2B

1.08e-081277415913604
Pubmed

Hemojuvelin regulates hepcidin expression via a selective subset of BMP ligands and receptors independently of neogenin.

BMPR1A BMPR1B ACVR2A ACVR2B

1.56e-081377418326817
Pubmed

Early development of electrical excitability in the mouse enteric nervous system.

SCN11A SCN5A SCN8A

1.04e-07577322875929
Pubmed

Bone morphogenetic protein receptor type II is a receptor for growth differentiation factor-9.

BMPR1A BMPR1B ACVR2A

1.04e-07577312135884
Pubmed

Structure/function characterization of micro-conotoxin KIIIA, an analgesic, nearly irreversible blocker of mammalian neuronal sodium channels.

SCN4A SCN5A SCN8A

1.04e-07577317724025
Pubmed

Truncated activin type II receptors inhibit bioactivity by the formation of heteromeric complexes with activin type I. receptors.

BMPR1B ACVR2A ACVR2B

1.04e-0757738612709
Pubmed

Cerebral Vein Malformations Result from Loss of Twist1 Expression and BMP Signaling from Skull Progenitor Cells and Dura.

BMPR1A BMPR1B ACVR2A ACVR2B

1.05e-072077428844842
Pubmed

Bone morphogenetic proteins.

BMPR1A BMPR1B ACVR2A ACVR2B

1.90e-072377415621726
Pubmed

Fstl1 antagonizes BMP signaling and regulates ureter development.

BMPR1A BMPR1B ACVR2A ACVR2B

2.71e-072577422485132
Pubmed

The TGFβ type I receptor TGFβRI functions as an inhibitor of BMP signaling in cartilage.

BMPR1A BMPR1B ACVR2A ACVR2B

3.20e-072677431311865
Pubmed

Type I receptor binding of bone morphogenetic protein 6 is dependent on N-glycosylation of the ligand.

BMPR1A BMPR1B ACVR2A

3.63e-07777318070108
Pubmed

Molecular recognition of BMP-2 and BMP receptor IA.

BMPR1A BMPR1B ACVR2B

3.63e-07777315064755
Pubmed

L-type voltage-dependent calcium channel alpha subunit 1C is a novel candidate gene associated with secondary hyperparathyroidism: an application of haplotype-based analysis for multiple linked single nucleotide polymorphisms.

KCNJ4 KCNJ6 SCAMP2 ACVR2A ACVR2B SLC1A7

8.11e-0714377620424473
Pubmed

New insights into the molecular mechanism of multiple synostoses syndrome (SYNS): mutation within the GDF5 knuckle epitope causes noggin-resistance.

BMPR1A BMPR1B ACVR2A

8.68e-07977321976273
Pubmed

Expression pattern of neuronal and skeletal muscle voltage-gated Na+ channels in the developing mouse heart.

SCN4A SCN5A SCN8A

8.68e-07977315746173
Pubmed

BMP signaling negatively regulates bone mass through sclerostin by inhibiting the canonical Wnt pathway.

BMPR1A BMPR1B ACVR2A ACVR2B

9.79e-073477418927151
Pubmed

Trait-associated noncoding variant regions affect TBX3 regulation and cardiac conduction.

HCN4 SCN5A CACNA1G

1.24e-061077332672536
Pubmed

RLP, a novel Ras-like protein, is an immediate-early transforming growth factor-beta (TGF-beta) target gene that negatively regulates transcriptional activity induced by TGF-beta.

BMPR1A BMPR1B ACVR2B

1.24e-061077315239668
Pubmed

International Union of Pharmacology. LI. Nomenclature and structure-function relationships of cyclic nucleotide-regulated channels.

HCN4 HCN3 CNGB1

1.24e-061077316382102
Pubmed

An improved method for the synthesis of cellulose membrane-bound peptides with free C termini is useful for PDZ domain binding studies.

KCNJ4 SCN4A ACVR2A ACVR2B SLC1A7

1.26e-068477515123239
Pubmed

Endoglin is an accessory protein that interacts with the signaling receptor complex of multiple members of the transforming growth factor-beta superfamily.

BMPR1B ACVR2A ACVR2B

1.70e-06117739872992
Pubmed

The STUbL RNF4 regulates protein group SUMOylation by targeting the SUMO conjugation machinery.

AMFR GBF1 HACD3 ATP6AP2 RNF149 SLC39A6 RTN3 COX15 SCAMP2 ABCD1 USP6NL GDE1 ANAPC4

2.24e-061203771329180619
Pubmed

A missense mutation of ErbB2 produces a novel mouse model of stillbirth associated with a cardiac abnormality but lacking abnormalities of placental structure.

HCN4 SCN5A CACNA1G

2.26e-061277332492036
Pubmed

TSC-22 promotes transforming growth factor β-mediated cardiac myofibroblast differentiation by antagonizing Smad7 activity.

BMPR1A BMPR1B ACVR2A

3.73e-061477321791611
Pubmed

Pacsin 2 is required for the maintenance of a normal cardiac function in the developing mouse heart.

HCN4 HCN3 SCN5A

3.73e-061477329107716
Pubmed

Assignment of the BMPR1A and BMPR1B genes to human chromosome 10q22.3 and 4q23-->q24 byin situ hybridization and radiation hybrid map ping.

BMPR1A BMPR1B

4.84e-0627729730621
Pubmed

Expression of bone morphogenetic protein receptors type-IA, -IB and -II correlates with tumor grade in human prostate cancer tissues.

BMPR1A BMPR1B

4.84e-06277210850425
Pubmed

Differential molecular regulation of processing and membrane expression of Type-I BMP receptors: implications for signaling.

BMPR1A BMPR1B

4.84e-06277228357470
Pubmed

Distinct roles of BMP receptors Type IA and IB in osteo-/chondrogenic differentiation in mesenchymal progenitors (C3H10T1/2).

BMPR1A BMPR1B

4.84e-06277215322331
Pubmed

Deubiquitination and stabilization of programmed cell death ligand 1 by ubiquitin-specific peptidase 9, X-linked in oral squamous cell carcinoma.

USP9X CD274

4.84e-06277229992764
Pubmed

Novel G protein-coupled receptors: a gene family of putative human olfactory receptor sequences.

OR1D5 OR1D2

4.84e-0627721315913
Pubmed

Mouse heart Na+ channels: primary structure and function of two isoforms and alternatively spliced variants.

SCN4A SCN5A

4.84e-06277211834499
Pubmed

BMPR1A is necessary for chondrogenesis and osteogenesis, whereas BMPR1B prevents hypertrophic differentiation.

BMPR1A BMPR1B

4.84e-06277232764110
Pubmed

[BMP7 signaling via BMPR1A, BMPR1B inhibits the proliferation of lung large carcinoma NCI-H460 cell].

BMPR1A BMPR1B

4.84e-06277220673479
Pubmed

Expression of activin receptor II and IIB mRNA isoforms in mouse reproductive organs and oocytes.

ACVR2A ACVR2B

4.84e-0627728049070
Pubmed

Specialized functions of Nav1.5 and Nav1.9 channels in electrogenesis of myenteric neurons in intact mouse ganglia.

SCN11A SCN5A

4.84e-06277224719102
Pubmed

Disease expression in Usher syndrome caused by VLGR1 gene mutation (USH2C) and comparison with USH2A phenotype.

ADGRV1 USH2A

4.84e-06277215671307
Pubmed

Characteristics of Retinitis Pigmentosa Associated with ADGRV1 and Comparison with USH2A in Patients from a Multicentric Usher Syndrome Study Treatrush.

ADGRV1 USH2A

4.84e-06277234638692
Pubmed

mRNAs for activin receptors II and IIB are expressed in mouse oocytes and in the epiblast of pregastrula and gastrula stage mouse embryos.

ACVR2A ACVR2B

4.84e-0627727748787
Pubmed

Epithelial Bmpr1a regulates differentiation and proliferation in postnatal hair follicles and is essential for tooth development.

BMPR1A BMPR1B

4.84e-06277215102710
Pubmed

Usher's Syndrome Type II: A Comparative Study of Genetic Mutations and Vestibular System Evaluation.

ADGRV1 USH2A

4.84e-06277228653555
Pubmed

Ca2+-dependent regulation of sodium channels NaV1.4 and NaV1.5 is controlled by the post-IQ motif.

SCN4A SCN5A

4.84e-06277230944319
Pubmed

Nomenclature of voltage-gated sodium channels.

SCN11A SCN7A

4.84e-06277211144347
Pubmed

Fibrodysplasia ossificans progressiva (FOP), a disorder of ectopic osteogenesis, misregulates cell surface expression and trafficking of BMPRIA.

BMPR1A ACVR2A

4.84e-06277215940369
Pubmed

BMPR1A and BMPR1B Missense Mutations Cause Primary Ovarian Insufficiency.

BMPR1A BMPR1B

4.84e-06277231769494
Pubmed

Formation and activation by phosphorylation of activin receptor complexes.

ACVR2A ACVR2B

4.84e-0627728721982
Pubmed

Tetraspanin 7 and its closest paralog tetraspanin 6: membrane organizers with key functions in brain development, viral infection, innate immunity, diabetes and cancer.

TSPAN7 TSPAN6

4.84e-06277232468130
Pubmed

Activin receptor type 2A (ACVR2A) functions directly in osteoblasts as a negative regulator of bone mass.

ACVR2A ACVR2B

4.84e-06277228659341
Pubmed

Structure of the mouse activin receptor type II gene.

ACVR2A ACVR2B

4.84e-0627721318045
Pubmed

Characterization of type II activin receptors. Binding, processing, and phosphorylation.

ACVR2A ACVR2B

4.84e-0627728395525
Pubmed

Expression of Fgf and Tgfbeta signaling related genes during embryonic endochondral ossification.

BMPR1A BMPR1B ACVR2A ACVR2B

5.13e-065177415963767
Pubmed

Defective Tbx2-dependent patterning of the atrioventricular canal myocardium causes accessory pathway formation in mice.

HCN4 SCN5A CACNA1G

5.72e-061677321266775
Pubmed

Sequence, structure, and evolution of a complete human olfactory receptor gene cluster.

OR1D5 OR1D4 OR1D2

5.72e-061677310673334
Pubmed

TGFbeta superfamily signals are required for morphogenesis of the kidney mesenchyme progenitor population.

BMPR1A BMPR1B ACVR2A ACVR2B

6.95e-065577415342483
Pubmed

An enhancer cluster controls gene activity and topology of the SCN5A-SCN10A locus in vivo.

SCN11A SCN5A ACVR2B

8.31e-061877331666509
Pubmed

Biochemical and Cellular Analysis Reveals Ligand Binding Specificities, a Molecular Basis for Ligand Recognition, and Membrane Association-dependent Activities of Cripto-1 and Cryptic.

BMPR1A ACVR2A ACVR2B

9.86e-061977328126904
Pubmed

The formation and function of the cardiac conduction system.

HCN4 SCN5A CACNA1G

1.35e-052177326786210
Pubmed

Expression and misexpression of members of the FGF and TGFbeta families of growth factors in the developing mouse pancreas.

BMPR1A BMPR1B ACVR2A ACVR2B

1.44e-056677412666204
Pubmed

Functional roles of Ca(v)1.3, Ca(v)3.1 and HCN channels in automaticity of mouse atrioventricular cells: insights into the atrioventricular pacemaker mechanism.

HCN4 CACNA1G

1.45e-05377221406960
Pubmed

Expression of activin subunits and receptors in the developing human ovary: activin A promotes germ cell survival and proliferation before primordial follicle formation.

ACVR2A ACVR2B

1.45e-05377214738881
Pubmed

Age-Associated Increase in BMP Signaling Inhibits Hippocampal Neurogenesis.

BMPR1A BMPR1B

1.45e-05377225538007
Pubmed

PDZD7 is a modifier of retinal disease and a contributor to digenic Usher syndrome.

ADGRV1 USH2A

1.45e-05377220440071
Pubmed

Dendrite complexity of sympathetic neurons is controlled during postnatal development by BMP signaling.

BMPR1A BMPR1B

1.45e-05377224048844
Pubmed

Distinct developmental programs require different levels of Bmp signaling during mouse retinal development.

BMPR1A BMPR1B

1.45e-05377215673568
Pubmed

New insights into the role of tetraspanin 6, 7, and 8 in physiology and pathology.

TSPAN7 TSPAN6

1.45e-05377239031113
Pubmed

Impact of a New Fusion Receptor on PD-1-Mediated Immunosuppression in Adoptive T Cell Therapy.

PTPRC CD274

1.45e-05377226105028
Pubmed

Structure of the ternary signaling complex of a TGF-beta superfamily member.

BMPR1A ACVR2A

1.45e-05377216672363
Pubmed

Glucosylceramide synthase and its functional interaction with RTN-1C regulate chemotherapeutic-induced apoptosis in neuroepithelioma cells.

UGCG RTN3

1.45e-05377212873973
Pubmed

Expression patterns of BMPRs in the developing mouse molar.

BMPR1A BMPR1B

1.45e-05377216432712
Pubmed

Activin type IIA and IIB receptors mediate Gdf11 signaling in axial vertebral patterning.

ACVR2A ACVR2B

1.45e-05377212414726
Pubmed

Analysis of the native murine bone morphogenetic protein serine threonine kinase type I receptor (ALK-3).

BMPR1A BMPR1B

1.45e-0537728707881
Pubmed

The mode of bone morphogenetic protein (BMP) receptor oligomerization determines different BMP-2 signaling pathways.

BMPR1A BMPR1B

1.45e-05377211714695
Pubmed

N6-methyladenosine regulator YTHDF1 represses the CD8 + T cell-mediated antitumor immunity and ferroptosis in prostate cancer via m6A/PD-L1 manner.

GPM6A CD274

1.45e-05377237698736
Pubmed

Transdifferentiation of alveolar epithelial type II to type I cells is controlled by opposing TGF-β and BMP signaling.

BMPR1A BMPR1B

1.45e-05377223831617
Pubmed

The type I BMP receptor ACVR1/ALK2 is required for chondrogenesis during development.

BMPR1A BMPR1B

1.45e-05377225413979
Pubmed

Granulosa cell-expressed BMPR1A and BMPR1B have unique functions in regulating fertility but act redundantly to suppress ovarian tumor development.

BMPR1A BMPR1B

1.45e-05377220363875
Pubmed

BMP signaling specifies the development of a large and fast CNS synapse.

BMPR1A BMPR1B

1.45e-05377223708139
Pubmed

Distinct spatial and temporal expression patterns of two type I receptors for bone morphogenetic proteins during mouse embryogenesis.

BMPR1A BMPR1B

1.45e-0537727750489
Pubmed

BMPR1a and BMPR1b signaling exert opposing effects on gliosis after spinal cord injury.

BMPR1A BMPR1B

1.45e-05377220130193
Pubmed

Assignment of ACVR2 and ACVR2B the human activin receptor type II and IIB genes to chromosome bands 2q22.2-->q23.3 and 3p22 and the human follistatin gene (FST) to chromosome 5q11.2 by FISH.

ACVR2A ACVR2B

1.45e-05377210702675
Pubmed

Presenilin Deficiency Results in Cellular Cholesterol Accumulation by Impairment of Protein Glycosylation and NPC1 Function.

NPC1 PSEN2

1.45e-05377238791456
Pubmed

Bone morphogenetic protein type IB receptor is progressively expressed in malignant glioma tumours.

BMPR1A BMPR1B

1.45e-0537728605097
Pubmed

Non-USH2A mutations in USH2 patients.

ADGRV1 USH2A

1.45e-05377222147658
Pubmed

Role of type I receptors for anti-Müllerian hormone in the SMAT-1 Sertoli cell line.

BMPR1A BMPR1B

1.45e-05377215897891
Pubmed

Soluble LR11/SorLA represses thermogenesis in adipose tissue and correlates with BMI in humans.

BMPR1A BMPR1B

1.45e-05377226584636
Pubmed

Expression of bone morphogenetic protein receptors in the developing mouse metanephros.

BMPR1A BMPR1B

1.45e-05377211701996
Pubmed

Inhibition of G protein-gated K+ channels by tertiapin-Q rescues sinus node dysfunction and atrioventricular conduction in mouse models of primary bradycardia.

SCN5A CACNA1G

1.45e-05377232555258
Pubmed

Regulation of muscle growth by multiple ligands signaling through activin type II receptors.

ACVR2A ACVR2B

1.45e-05377216330774
Pubmed

Human voltage-gated sodium channel mutations that cause inherited neuronal and muscle channelopathies increase resurgent sodium currents.

SCN4A SCN5A

1.45e-05377220038812
Pubmed

Frequent expression of CD45RO memory T cell marker as well as low to high expression of PD-1 and PD-L1 inhibitory molecules in seminoma and dysgerminoma.

PTPRC CD274

1.45e-05377238171036
InteractionRGMB interactions

BMPR1A BMPR1B ACVR2A ACVR2B

1.22e-088754int:RGMB
InteractionIGSF1 interactions

BMPR1A BMPR1B ACVR2A ACVR2B

2.34e-0715754int:IGSF1
InteractionHEPACAM2 interactions

BMPR1A UGCG RNF149 ACVR2A ACVR2B

3.25e-0739755int:HEPACAM2
InteractionSCN8A interactions

SCN11A SCN4A SCN5A SCN8A

8.19e-0720754int:SCN8A
InteractionBMP6 interactions

BMPR1A BMPR1B ACVR2A ACVR2B

1.01e-0621754int:BMP6
InteractionRNF133 interactions

BMPR1A GBF1 UGCG RNF149

2.11e-0625754int:RNF133
InteractionBMP2 interactions

BMPR1A BMPR1B ACVR2A ACVR2B

2.49e-0626754int:BMP2
InteractionGDF5 interactions

BMPR1A BMPR1B ACVR2A ACVR2B

8.49e-0635754int:GDF5
InteractionMRAP2 interactions

BMPR1A UGCG RNF149 ACVR2A ACVR2B

1.00e-0577755int:MRAP2
InteractionGPR35 interactions

NPC1 KCNJ4 TSPAN7 SLC39A6 RTN3 SCAMP2

1.02e-05133756int:GPR35
InteractionRAB14 interactions

NPC1 GPM6A ATP6AP2 RNF149 TSPAN6 CD274 SCAMP2

2.05e-05225757int:RAB14
InteractionSCN11A interactions

SCN11A SCN5A SCN8A

2.18e-0515753int:SCN11A
InteractionRNF149 interactions

GPM6A AMFR BMPR1A HACD3 ATP6AP2 RNF149 SLC39A6 SCAMP2 ACVR2A ACVR2B

3.51e-055497510int:RNF149
InteractionPARP16 interactions

NPC1 MDN1 HACD3 SCN4A

3.58e-0550754int:PARP16
InteractionTM6SF1 interactions

TM6SF1 MFF

4.09e-053752int:TM6SF1
InteractionPEG10 interactions

BMPR1A BMPR1B USP9X ACVR2A ACVR2B

4.72e-05106755int:PEG10
InteractionGPR182 interactions

AMFR GBF1 MDN1 CLMN POLG SLC39A6 COX15 SCAMP2 ABCD1

4.73e-05455759int:GPR182
InteractionCRLF2 interactions

BMPR1A UGCG RNF149 ACVR2A

7.86e-0561754int:CRLF2
InteractionRTN1 interactions

GPM6A AMFR UGCG RTN3 SCAMP2

8.52e-05120755int:RTN1
InteractionEDAR interactions

BMPR1A UGCG RNF149 ACVR2A

9.49e-0564754int:EDAR
InteractionDERL2 interactions

NPC1 GPM6A AMFR GBF1 RTN3

9.95e-05124755int:DERL2
InteractionRHOA interactions

NPC1 BMPR1A MDN1 HACD3 ATP6AP2 USP9X UGCG RNF149 SLC39A6 RTN3 COX15 ABCD1 USP6NL MFF

1.19e-0411997514int:RHOA
InteractionGPR45 interactions

AMFR GBF1 MDN1 ATP6AP2 POLG SLC39A6 ACVR2A

1.26e-04300757int:GPR45
InteractionMARCHF1 interactions

BMPR1A RNF149 ACVR2A ADGRL3

1.35e-0470754int:MARCHF1
InteractionCCDC126 interactions

GPM6A MFF

1.36e-045752int:CCDC126
InteractionTSPAN17 interactions

GPM6A BMPR1A HACD3 RNF149

1.50e-0472754int:TSPAN17
InteractionKCNK18 interactions

BMPR1A UGCG ACVR2A

1.69e-0429753int:KCNK18
InteractionART3 interactions

MDN1 PSEN2 SCAMP2

1.69e-0429753int:ART3
InteractionATP2A1 interactions

MDN1 HACD3 CLMN ATP6AP2 USP9X RTN3 COX15 ABCD1

1.74e-04423758int:ATP2A1
InteractionSYNGR2 interactions

NPC1 ATP6AP2 CD274 SCAMP2

1.76e-0475754int:SYNGR2
InteractionRETREG3 interactions

AMFR USP9X SLC39A6 RTN3 SCAMP2 MFF

1.78e-04222756int:RETREG3
InteractionSYVN1 interactions

NPC1 AMFR CLMN ATP6AP2 SCN4A RNF149 RTN3

2.03e-04324757int:SYVN1
InteractionMROH2B interactions

GBF1 MROH2B

2.03e-046752int:MROH2B
InteractionDHCR24 interactions

NPC1 AMFR CD274 RTN3 ANAPC4

2.14e-04146755int:DHCR24
InteractionBMP7 interactions

BMPR1A BMPR1B ACVR2A ACVR2B

2.26e-0480754int:BMP7
InteractionCTXN1 interactions

BMPR1A UGCG ACVR2A

2.49e-0433753int:CTXN1
InteractionDLG2 interactions

KCNJ4 KCNJ6 SCN4A SCN5A

2.60e-0483754int:DLG2
InteractionGINM1 interactions

BMPR1A RNF149 ACVR2A ACVR2B

2.73e-0484754int:GINM1
InteractionGJD3 interactions

NPC1 GBF1 HACD3 ATP6AP2 RNF149 SLC39A6 RTN3 USP6NL

2.81e-04454758int:GJD3
InteractionINHBC interactions

ACVR2A ACVR2B

2.84e-047752int:INHBC
InteractionGDF6 interactions

BMPR1A BMPR1B

2.84e-047752int:GDF6
InteractionGDF2 interactions

ACVR2A ACVR2B

2.84e-047752int:GDF2
InteractionSLC20A1 interactions

BMPR1A UGCG RNF149 ACVR2B

3.40e-0489754int:SLC20A1
InteractionRAB9A interactions

NPC1 HACD3 SLC38A9 CLMN ATP6AP2 RNF149 SLC39A6 RTN3 SCAMP2

3.55e-04595759int:RAB9A
InteractionIL17RB interactions

BMPR1A RNF149 ACVR2B

3.80e-0438753int:IL17RB
InteractionADGRG5 interactions

GPM6A BMPR1A KLRG2 ACVR2B

4.02e-0493754int:ADGRG5
InteractionATP2A2 interactions

NPC1 AMFR BMPR1A HACD3 RNF149 CD274 HACD1

4.44e-04369757int:ATP2A2
InteractionACVR2B interactions

BMPR1A RNF149 ACVR2A ACVR2B

4.72e-0497754int:ACVR2B
InteractionHCN4 interactions

HCN4 HCN3

4.84e-049752int:HCN4
InteractionACVR2A interactions

BMPR1A RNF149 ACVR2A ACVR2B

5.30e-04100754int:ACVR2A
InteractionSMIM5 interactions

BMPR1A RNF149 KLRG2

5.49e-0443753int:SMIM5
InteractionLRRIQ1 interactions

BMPR1A ACVR2A ACVR2B

5.49e-0443753int:LRRIQ1
InteractionDLK1 interactions

PSEN2 RNF149 SCAMP2 ACVR2B

5.50e-04101754int:DLK1
InteractionATP2C1 interactions

NPC1 SCN11A SCN5A RNF149

5.50e-04101754int:ATP2C1
InteractionRUSF1 interactions

BMPR1A UGCG RNF149 ACVR2A ACVR2B

5.74e-04181755int:RUSF1
InteractionMANSC1 interactions

BMPR1A RNF149 KLRG2 ACVR2B

6.14e-04104754int:MANSC1
InteractionSNTA1 interactions

KCNJ4 SCN4A SCN5A SLC1A7

6.37e-04105754int:SNTA1
InteractionTMEM192 interactions

NPC1 USP9X RNF149 TSPAN6 KLRG2

6.65e-04187755int:TMEM192
InteractionCANX interactions

NPC1 AMFR BMPR1A HACD3 CLMN ATP6AP2 RNF149 TSPAN6 SLC39A6 COX15 ACVR2A ACVR2B NRP2

7.09e-0412617513int:CANX
InteractionSCN5A interactions

SCN11A SCN5A SCN8A

7.14e-0447753int:SCN5A
InteractionNODAL interactions

ACVR2A ACVR2B

7.35e-0411752int:NODAL
InteractionHCN3 interactions

HCN4 HCN3

7.35e-0411752int:HCN3
InteractionSCN10A interactions

SCN11A SCN5A

7.35e-0411752int:SCN10A
InteractionPDE1A interactions

PDE1A GBF1

7.35e-0411752int:PDE1A
InteractionBMPR2 interactions

BMPR1A BMPR1B RNF149 ACVR2A

7.58e-04110754int:BMPR2
InteractionAPBA2 interactions

PSEN2 KLRG2 SP110

7.59e-0448753int:APBA2
CytobandXp11.4

ATP6AP2 USP9X TSPAN7

2.61e-0534773Xp11.4
Cytoband17p13.3

OR1D5 OR1D4 OR1D2

4.49e-048877317p13.3
Cytoband3p21

SCN5A CCRL2

1.42e-03337723p21
Cytoband10q24

GBF1 COX15

1.59e-033577210q24
Cytoband6p12.3

ADGRF5 RHAG

1.69e-03367726p12.3
CytobandEnsembl 112 genes in cytogenetic band chr17p13

OR1D5 TRPV3 OR1D4 OR1D2

2.78e-03346774chr17p13
CytobandEnsembl 112 genes in cytogenetic band chr3p22

SCN11A SCN5A ACVR2B

3.73e-03184773chr3p22
GeneFamilySodium voltage-gated channel alpha subunits

SCN11A SCN4A SCN5A SCN8A

1.27e-0895941203
GeneFamilyCyclic nucleotide gated channels

HCN4 HCN3 CNGB1

3.90e-0610593250
GeneFamilyFibronectin type III domain containing|USH2 complex

ADGRV1 USH2A

6.26e-0545921244
GeneFamilyType 2 receptor serine/threonine kinases

ACVR2A ACVR2B

1.04e-045592346
GeneFamilyType 1 receptor serine/threonine kinases

BMPR1A BMPR1B

2.18e-047592345
GeneFamilyOlfactory receptors, family 1

OR1D5 OR1D4 OR1D2

2.99e-0440593147
GeneFamilyPotassium voltage-gated channel subfamily J

KCNJ4 KCNJ6

1.22e-0316592276
GeneFamilyADAM metallopeptidase domain containing|CD molecules

BMPR1A BMPR1B PTPRC TSPAN7 CD274 RHAG

1.75e-03394596471
GeneFamilySolute carriers

SLC9C1 SLC38A9 SLC39A6 FLVCR2 SLC1A7 RHAG

1.78e-03395596752
GeneFamilyCD molecules|Tetraspanins

TSPAN7 TSPAN6

5.18e-0333592768
GeneFamilyX-linked mental retardation|Angiotensin receptors

USP9X TSPAN7

1.30e-0253592103
ToppCell10x3'2.3-week_14-16-Endothelial-stroma-sinusoidal_EC|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

GPM6A PIEZO2 UGCG TSPAN7 TSPAN6 ADGRF5 NRP2

5.15e-08197777f1080d93acf1a4756d2f2c8cabd1fb50bc7bcd09
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Transitional_Principal-Intercalated_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

AMFR BMPR1B ATP6AP2 SLC39A6 ADGRF5 HACD1

4.56e-07167776166b7b4ca0663cde6d88219ee0bcc1988d03dab8
ToppCellIonocyte|World / Class top

HACD3 ATP6AP2 PLCD4 ADGRF5 TM6SF1 GDE1

5.06e-07170776d2e592f2a679e6a8d32f2b752d9a3c493e50ced4
ToppCell3'-Pediatric_IBD-SmallIntestine-Endothelial-lymphatic_endothelial-LEC1_(ACKR4+)|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract

GPM6A PDE1A PIEZO2 TSPAN7 PLCD4 NRP2

5.06e-071707764848965bc7e9356c6601bb41eeea1553d2eea87e
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_2-Exc_L3-4_RORB_PRSS12|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

BMPR1B SLC9C1 CLMN ADGRF5 UNC13C CNGB1

5.60e-071737768ac2e9d39c0f76e674f8bd59d1da246bab4867c8
ToppCell5'-Adult-SmallIntestine-Mesenchymal-fibroblastic-Stromal_3_(C7+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PIEZO2 NWD2 SCN7A PLCD4 CACNA1G ATP10D

6.40e-07177776bd602db857f37869ef76d14c05ef522c509f08ee
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PDE1A BMPR1B SLC9C1 RTN3 UNC13C GPR160

1.09e-0619477604bfc555743f7d8821439d05ae442d15e9886c59
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

BMPR1B HACD3 SLC39A6 RTN3 UNC13C GPR160

1.09e-061947764d6c9b016e3a0641954a8ea10c97d1cd76fadd9f
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PDE1A BMPR1B SLC9C1 RTN3 UNC13C GPR160

1.09e-0619477669bff17df4a760ccf081cf52ff04af02c14f448d
ToppCell(4)_Endothelial_cells-(42)_EC-sinusoidal|World / Cell class and subclass of bone marrow stroma cells in homeostatis

GPM6A UGCG TSPAN7 ADGRF5 TM6SF1 GPR160

1.09e-061947764428b472c2042f88eae028b1770767512a515b75
ToppCellkidney_cells-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

BMPR1B HACD3 ATP6AP2 SLC39A6 RTN3 ADGRF5

1.16e-06196776cd8c22c6f52f068a33525723108d6b5b23fe822d
ToppCell10x5'v1-week_14-16-Endothelial-stroma-sinusoidal_EC|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

GPM6A PIEZO2 TSPAN7 TSPAN6 ADGRF5 NRP2

1.31e-06200776ae429f2de652cc1976e63644781197e9ce0e70c8
ToppCellPND03-Endothelial-Endothelial_blood-vessel-Microvascular_EC-CAP1-CAP1_prolif|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

PIEZO2 SCN7A TSPAN7 ADGRF5 TRPV3

7.83e-061577752c946c6ab284fac3c25db688ed0aabe5a3f9ffa5
ToppCellChildren_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

GPM6A BMPR1B KCNJ6 ADGRF5 ADGRV1

8.33e-061597758680b054622f573a82b1625fb93c2d5db81d1034
ToppCell356C-Fibroblasts-Fibroblast-G-|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

PIEZO2 SCN7A CD274 PLCD4 TM6SF1

8.58e-061607750293b244c063a62819690bf22bbc2681f8d15252
ToppCell356C-Fibroblasts-Fibroblast-G|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

PIEZO2 SCN7A CD274 PLCD4 TM6SF1

8.58e-061607753eaae86fa08f7651021316f8e5811bf48055591e
ToppCellfacs-Trachea-nan-18m-Myeloid-granulocyte|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SCN11A PTPRC LIPM CD274 CCRL2

1.03e-051667757f8b4cf63c3e292ae421f111edaa4572717f4db1
ToppCell5'-Adult-Appendix-Hematopoietic-Myeloid-Lymphoid_DC|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TMC1 CD274 PLCD4 CNGB1 NRP2

1.06e-051677758b223333c0c7a85b5a1af6f2f5b12ee0d94357f6
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_2-Exc_L3-5_RORB_HSPB3|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

NWD2 CLMN ADGRF5 UNC13C CNGB1

1.15e-05170775985c6c9e3c593ed0628a481f06c2c91b2ab5d746
ToppCellControl-Epithelial_cells-ECM-high_epithelial|Control / group, cell type (main and fine annotations)

GPM6A SLC9C1 ADGRF5 ADGRV1 OR1D2

1.15e-05170775e2023d66e70983c87dacbd6181d3426488d1fc57
ToppCellBAL-Mild-Epithelial-Epithelial-AT1/AT2|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

PDE1A KCNJ6 ADGRF5 UNC13C ADGRL3

1.29e-05174775b7f5492ce8098f7eb0aef30ee558d00738d59d0e
ToppCellBAL-Mild-Epithelial-Epithelial-AT1/AT2-|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

PDE1A KCNJ6 ADGRF5 UNC13C ADGRL3

1.29e-0517477571730503be3d9c839c4c9e950145e2101d682a1c
ToppCellBAL-Mild-Epithelial-Epithelial-AT1/AT2|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)

PDE1A KCNJ6 ADGRF5 UNC13C ADGRL3

1.29e-05174775ee8ac51fa0b426ad7b7453371bb79c8bf8c1d358
ToppCellBAL-Mild-Epithelial-Epithelial-AT1/AT2-|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

PDE1A KCNJ6 ADGRF5 UNC13C ADGRL3

1.29e-05174775cafe4d6b5f08d8888e9db6e196c66df991c03e7b
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

AMFR PDE1A BMPR1B ATP6AP2 ADGRF5

1.29e-051747755f4436863a40f8bca46e2989bca66c02b6be88d4
ToppCellPND10-Endothelial-Endothelial_blood-vessel-Microvascular_EC-CAP1-CAP1_prolif|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

PIEZO2 SCN7A TSPAN7 TSPAN6 ADGRF5

1.36e-05176775269326c2bf44a9003d95bc6dbc839f08f25737ca
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Intercalated_Cell_Type_B|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

BMPR1B ATP6AP2 KCNJ6 UNC13C NRP2

1.36e-051767756c7edf1cb38644500bce6c5a1dd90bbe17415cdb
ToppCellfacs-Aorta-Heart-24m-Endothelial-nan|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

UGCG TSPAN7 TSPAN6 CD274 ADGRF5

1.40e-05177775c6b955765aee8a196fcf4f7bb16139c95b76dc4e
ToppCellfacs-Aorta-Heart-24m-Endothelial-aortic_endothelial_cell|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

UGCG TSPAN7 TSPAN6 CD274 ADGRF5

1.44e-051787758017aaecd6275d8173c516f6f3a68ea991f3c1b0
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Intercalated_Cell_Type_B|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

BMPR1B PTPRC ATP6AP2 KCNJ6 UNC13C

1.44e-0517877551d2188406f04329311b2efd1108fc36617a860e
ToppCellfacs-Aorta-Heart-24m-Endothelial|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

UGCG TSPAN7 TSPAN6 CD274 ADGRF5

1.44e-0517877546333db0d205580189062bf9df839c97196ad161
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Intercalated_Cell_Type_B|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

BMPR1B PSEN2 ATP6AP2 KCNJ6 UNC13C

1.52e-05180775cfc8bfbfd3617aabbb49f9730c29b673ca157e74
ToppCellfacs-Heart-RA-24m-Endothelial|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GPM6A TSPAN7 TSPAN6 ADGRF5 CNGB1

1.52e-05180775174c643e046646e3b305dd7e5b120d2c9a46690f
ToppCellRA-16._Neuronal|RA / Chamber and Cluster_Paper

BMPR1B CLMN SCN7A ADGRL3 RHAG

1.52e-051807755842febfdabac61ce970254fb0ef17a628f1b8c0
ToppCellRA-16._Neuronal|World / Chamber and Cluster_Paper

BMPR1B CLMN SCN7A ADGRL3 RHAG

1.56e-051817757d22a43f887e0747f0cb87ba364ff27905ee6eec
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

PDE1A NWD2 ADGRF5 UNC13C CNGB1

1.60e-0518277514a117c5e50db31ee1b2cf4df4d133451fd6d55f
ToppCellpdx-Tumor_cells-T6|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)

SCN7A UGCG USP6NL GPR160 NRP2

1.60e-051827757b24a4f712e1ae1525e8f1c8ec4e1fc43489cbee
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PIEZO2 UNC13C ADGRV1 USH2A ADGRL3

1.69e-051847752cbed6462fea2622871bb7e49b0df3d984239281
ToppCelldroplet-Heart-4Chambers-21m-Endothelial|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GPM6A TSPAN7 TSPAN6 ADGRF5 NRP2

1.69e-05184775f17d713af4a97dff4eeeab24c405677ef2ffcf84
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PIEZO2 UNC13C ADGRV1 USH2A ADGRL3

1.69e-05184775ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PIEZO2 UNC13C ADGRV1 USH2A ADGRL3

1.69e-051847752b19a8c5f823e00812908b23e66bb4e563278aff
ToppCelldroplet-Lung-LUNG-1m-Myeloid|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PTPRC CLMN RNF149 FLVCR2 TM6SF1

1.73e-0518577553a5218c1e6eb12daccde3d6e02f337e2586d74c
ToppCelldroplet-Tongue-nan-24m-Epithelial-suprabasal|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ACER1 LIPM TSPAN7 SLC39A6 NRP2

1.78e-051867752913b5fd0617d024d600ba7015ec7b1961dade83
ToppCell5'-GW_trimst-2-LargeIntestine-Mesenchymal-myocytic-SMC_(PLPP2+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

GPM6A BMPR1B PLCD4 HACD1 NRP2

1.82e-051877753912bbb610a4a84791e9bda92a2d57a52c31d29e
ToppCellFetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_1-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

NPC1 SLC9C1 CLMN CD274 USP6NL

1.87e-0518877543a3a59f92ad93509d4166bd025aed0b1b39a008
ToppCellfacs-Skin-nan-18m-Mesenchymal-nan|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GPM6A PDE1A CACNA1G SP110 NRP2

1.92e-0518977529287525120be2953b76881ba3cfc4379c265e7a
ToppCellfacs-Skin-nan-18m-Mesenchymal-fibroblast|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GPM6A PDE1A CACNA1G SP110 NRP2

1.92e-051897757150dad9a92a715487c2d8130fa01b752ea69663
ToppCellfacs-Skin-nan-18m-Mesenchymal|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GPM6A PDE1A CACNA1G SP110 NRP2

1.92e-051897756e4c0effd5192fd00052abc048fdb87a74fb6554
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell_of_renal_cortex|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

GPM6A PIEZO2 TM6SF1 RHAG NRP2

1.97e-05190775876bd2eb9ed2624cb23bdcf6b989e4fa34d099e3
ToppCellkidney_cells-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Connecting_Tubule_Intercalated_Cell_Type_A|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

AMFR HACD3 ATP6AP2 TSPAN7 ADGRF5

1.97e-05190775223587b5df037794a2cee234babf87d12bf48ac8
ToppCellnormal_Lymph_Node-Myeloid_cells-Activated_DCs|normal_Lymph_Node / Location, Cell class and cell subclass

SCN11A PIEZO2 PSEN2 CD274 NRP2

1.97e-0519077515978ddd37b521343f88b62dad1643077fc22b2b
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell_of_renal_cortex-lymphatic_endothelial_cell_of_renal_cortex|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

GPM6A PIEZO2 TM6SF1 RHAG NRP2

1.97e-05190775be9f36127028f52ca5fc1b32ba15a6c26aad69ac
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Endothelial-lymphatic_endothelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

GPM6A PIEZO2 TM6SF1 RHAG NRP2

1.97e-0519077509a8855901c3c9332dbaab3e40166485b696d0f1
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Inner_Medullary_Collecting_Duct_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PDE1A BMPR1B SLC9C1 UNC13C GPR160

2.02e-051917753e828cffa24ded19f591a7ed6c1fe88ad57fdcac
ToppCellEpithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)|World / Lineage, Cell type, age group and donor

GPM6A SLC9C1 ADGRF5 ADGRV1 LARGE1

2.02e-05191775d3733c8c4bda70c4390e5601fdda6188a64be944
ToppCellkidney_cells-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

BMPR1B HACD3 SLC39A6 RTN3 HACD1

2.07e-051927759e031bf93eb8757fdd0cc22f01b44e48f85532d5
ToppCellkidney_cells-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Degenerative_Outer_Medullary_Collecting_Duct_Principal_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

BMPR1B HACD3 SLC39A6 RTN3 HACD1

2.07e-051927753d777d07878269b87ec7e1f06489cae7c989d633
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Degenerative_Outer_Medullary_Collecting_Duct_Principal_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

BMPR1B HACD3 SLC39A6 RTN3 HACD1

2.07e-05192775d5ec4cdb15620a5abfc83577353501186c2bc86a
ToppCelldroplet-Lung-LUNG-30m-Endothelial-Capillary_Aerocyte_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PDE1A PIEZO2 SCN7A TSPAN7 ADGRF5

2.07e-0519277535f7926628a967f85b26371e795a1b93c6f103ab
ToppCell(4)_Endothelial_cells|World / Cell class and subclass of bone marrow stroma cells in homeostatis

GPM6A UGCG TSPAN7 ADGRF5 TM6SF1

2.12e-05193775ae6ba13d4d9f2a700887cdda2790c32007b29ac8
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

BMPR1B HACD3 SLC39A6 RTN3 HACD1

2.12e-051937755da60321bcf761913eb30779b6d8b1e933c5e51e
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Degenerative_Outer_Medullary_Collecting_Duct_Principal_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

BMPR1B HACD3 SLC39A6 RTN3 GPR160

2.17e-05194775be869e186386d03ebb670971dd24fa656b4b0edf
ToppCelldroplet-Lung-30m-Endothelial-capillary_endothelial-capillary_endothelial_cell-capillary_aerocyte_endothelial_cell|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

PDE1A PIEZO2 SCN7A TSPAN7 ADGRF5

2.17e-05194775cf7f232827945fbafd2c298c08a799ab916c2472
ToppCelldroplet-Tongue-TONGUE-1m-Epithelial-suprabasal|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ACER1 LIPM TSPAN7 SLC39A6 NRP2

2.17e-05194775a3adcdc8b87332e8beb9bcd70cf36424af10633d
ToppCell(4)_Endothelial_cells-(42)_EC-sinusoidal|(4)_Endothelial_cells / Cell class and subclass of bone marrow stroma cells in homeostatis

GPM6A PSEN2 UGCG TSPAN7 GPR160

2.17e-051947754199900d16623eca02d674d5ada7f0989e47955e
ToppCellfacs-Lung-nan-3m-Endothelial-endothelial_cell_of_lung|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PIEZO2 SCN7A TSPAN7 ADGRF5 ADGRL3

2.17e-05194775f159ef8541d75a4e98468947f231bb463bec922c
ToppCellChildren_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

NPC1 ADGRF5 ADGRV1 GPR160 LARGE1

2.17e-0519477597534c8bba895a7913665e03ae4e5c4a6ad71daf
ToppCellfacs-Heart-LA-3m-Endothelial|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GPM6A TSPAN7 TSPAN6 ADGRF5 NRP2

2.17e-0519477533cc4f1d716cb71d54cdedbe9bbdc0d7b17c4777
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

GPM6A PIEZO2 SCN4A ADGRF5 NRP2

2.17e-05194775e55dc30e200c9f576804acb642175eb4fa9146b5
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

BMPR1B HACD3 ATP6AP2 SLC39A6 RTN3

2.23e-051957750ac7762197cdd8d643f87148573a8df6e936c1b0
ToppCellTracheal-NucSeq-Endothelial-Endothelia_lymphatic-Endothelia_Lymphatic|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

GPM6A PDE1A PIEZO2 TSPAN7 NRP2

2.28e-0519677509a7edf4a7defb7fe70d9777dd9500ee8421ff31
ToppCellTracheal-NucSeq-Endothelial-Endothelia_lymphatic|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

GPM6A PDE1A PIEZO2 TSPAN7 NRP2

2.28e-05196775e50d2c66d5c5cd25fdfecdcc4c8506a1d0a85755
ToppCellbackground-Endothelial_cells|background / Sample and Cell Type and Tumor Cluster (all cells)

GPM6A PIEZO2 TSPAN7 ADGRF5 NRP2

2.28e-05196775e6fb0bfab1779ec64a8c35d01519eaafbf62e977
ToppCell10x3'2.3-week_17-19-Endothelial-stroma-sinusoidal_EC|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

PIEZO2 TSPAN7 TSPAN6 ADGRF5 NRP2

2.34e-051977754e58bbf3ecb30b4c8199adcc04d2eb134d90de56
ToppCellTracheal-NucSeq-Stromal-Myofibroblastic-Muscle_smooth_pulmonary|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

GPM6A CCRL2 HACD1 ADGRL3 NRP2

2.34e-05197775ac4f53acb2f8a428b0f2fab3c30a34e095a1bed7
ToppCellfacs-Brain_Non-Myeloid-Cortex-3m|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NPC1 AMFR CLMN TSPAN7 RTN3

2.40e-05198775a7e5de81eb7d3d23812c179a001adbaab1506596
ToppCellBronchial-NucSeq-Endothelial-Endothelia_lymphatic-Endothelia_Lymphatic|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

GPM6A PDE1A PIEZO2 RHAG NRP2

2.40e-05198775b3a020522e064bb61949d38e442f24026e339364
ToppCellBronchial-NucSeq-Endothelial-Endothelia_lymphatic|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

GPM6A PDE1A PIEZO2 RHAG NRP2

2.40e-05198775fc4b7c3ad52bc5c8b40fa04a156bfbb58afa2872
ToppCell10x3'2.3-week_14-16-Endothelial|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

PIEZO2 UGCG TSPAN7 ADGRF5 NRP2

2.46e-0519977541f046646fff65b7e51b63d3204f76ef32054781
ToppCell10x3'2.3-week_14-16-Endothelial-stroma|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

PIEZO2 UGCG TSPAN7 ADGRF5 NRP2

2.46e-05199775ef7f7f7c861827574b120f48cf4052c563929081
ToppCellLPS-antiTNF-Epithelial_alveolar-Mes-like|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

MDN1 KCNJ6 COX15 ADGRL3

8.60e-0513477464979e1a056b7406e1be39c5ebe2f8d731ac3c17
ToppCellCOVID-19_Convalescent-PLT_3|World / Disease Group and Platelet Clusters

NPC1 HCN3 SLC39A6 USP6NL

9.37e-05137774bb54bb81b450462ad521b57e1a07a80ce1678e67
ToppCellBac-SEP-Lymphocyte-T_NK-CD8_Naive|Bac-SEP / Disease, Lineage and Cell Type

BMPR1A TSPAN6 PLCD4 HACD1

1.14e-04144774fdcf84e8b5fdc0730f243919f9cc30492e24dd75
ToppCellfacs-Lung-Endomucin-24m-Endothelial-Capillary_Type_1_Cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC9C1 NWD2 ADGRV1 USH2A

1.17e-0414577496712c68ab759d7ade0d912581a1a7c25dc6def8
ToppCellLPS-antiTNF-Stromal_mesenchymal-Myocytic-Pericyte_3|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SLC9C1 HCN4 CLMN HACD1

1.20e-041467742ac9b487a7991fdc15444aeb93533030e09825bb
ToppCellCOVID-19-kidney-Technical/muscle_(PCT)|kidney / Disease (COVID-19 only), tissue and cell type

KCNJ6 TRPV3 USH2A ADGRL3

1.20e-04146774c55f1bdb6ac43b4118cb27ea7c879527e1afcbab
ToppCellRV-16._Neuronal|World / Chamber and Cluster_Paper

CLMN SCN7A ADGRL3 RHAG

1.30e-041497743a2f8c4173dcf9e3f8d3b8ffddbc597098adf7a9
ToppCellNS-critical-d_16-33-Myeloid-Monocyte-derived_Macrophage|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

POLG CD274 ABCD1 HACD1

1.43e-04153774859de35b24c5d7d73be1c213b90b43362ee2e0eb
ToppCellRV-16._Neuronal|RV / Chamber and Cluster_Paper

CLMN SCN7A ADGRL3 RHAG

1.43e-04153774bed8bbf5c5cbfbf46a816066da472c3fdddecb5d
ToppCellLPS-IL1RA-Myeloid_granulocytic|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

GPM6A GBF1 TRPV3 UNC13C

1.47e-04154774d55fb73461885e1e02061a344ff89624ef4de487
ToppCellfacs-Marrow-KLS-18m-Lymphocytic|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PDE1A SCN7A TSPAN7 ADGRV1

1.47e-0415477437765512dfae557b9f6eb30a29463b93682a4404
ToppCellLPS-IL1RA-Myeloid_granulocytic-Neutrophils|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

GPM6A GBF1 TRPV3 UNC13C

1.47e-0415477443735f7c58cac51855ded486ee8d8729a1b9909e
ToppCell368C-Endothelial_cells-Endothelial-E|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)

AMFR CD274 ADGRF5 UNC13C

1.55e-041567744877aabf647238c0279e497345b6a6d5ee07ef9c
ToppCell368C-Endothelial_cells-Endothelial-E-|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)

AMFR CD274 ADGRF5 UNC13C

1.55e-041567741d681fa17e62815f5d5f90c86be3c248b38e011b
ToppCellPND07-Endothelial-Endothelial_blood-vessel-Microvascular_EC-EPC-EPC_mature|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

PIEZO2 SCN7A KLRG2 PLCD4

1.55e-041567741928c86deb3bcd01db4ae76919a351066aadb39a
ToppCellChildren_(3_yrs)-Mesenchymal-chondrocyte-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

PIEZO2 MROH2B SCN7A PLCD4

1.62e-04158774e5636c0b608d68bd426a2b446ac508e4512e86a4
ToppCellPND10-Immune-Immune_Myeloid-Granulocytic-Mast|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

GPM6A PSEN2 HCN3 CD274

1.70e-041607746393e3d5c5c8176c93aecd89b313bd054a00d474
ToppCellPND10-Immune-Immune_Myeloid-Granulocytic-Mast-Mast_mature|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

GPM6A PSEN2 HCN3 CD274

1.70e-041607742065938e944eb99478fd8132c2c03adeaee6d447
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-lymphatic_endothelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

GPM6A PIEZO2 RHAG NRP2

1.74e-04161774fb59d96c2aa9e4654f02bf6ce36bf832776cb4dd
ToppCellfacs-Pancreas-Endocrine-24m-Hematologic-nan|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PTPRC CCRL2 TM6SF1 SP110

1.74e-041617745680939068b5a63aa1064202b4ee8847156c8ccd
DrugZonisamide

SCN11A SCN4A SCN5A CACNA1G

2.78e-0717774DB00909
DrugCID5255110

HCN4 KCNJ4 KCNJ6 SCN4A HCN3

1.42e-0657775CID005255110
DrugTrifluridine [70-00-8]; Up 200; 13.6uM; HL60; HT_HG-U133A

GPM6A CACNA1G CNGB1 SLC1A7 RHAG NRP2 LARGE1

5.03e-061997776136_UP
DrugFlecainide

SCN4A SCN5A

1.13e-052772DB01195
Diseasegeneralized epilepsy with febrile seizures plus 2 (implicated_via_orthology)

SCN11A SCN4A SCN5A SCN7A SCN8A

2.64e-1110775DOID:0111294 (implicated_via_orthology)
DiseaseDravet syndrome (implicated_via_orthology)

SCN11A SCN4A SCN5A SCN7A SCN8A

2.64e-1110775DOID:0080422 (implicated_via_orthology)
Diseasegeneralized epilepsy with febrile seizures plus (implicated_via_orthology)

SCN11A SCN4A SCN5A SCN7A SCN8A

8.28e-1112775DOID:0060170 (implicated_via_orthology)
Diseasejuvenile polyposis syndrome (implicated_via_orthology)

BMPR1A BMPR1B ACVR2A ACVR2B

3.01e-0813774DOID:0050787 (implicated_via_orthology)
Diseaseepilepsy (implicated_via_orthology)

SCN11A SCN4A SCN5A SCN7A SCN8A UNC13C SLC1A7

2.40e-07163777DOID:1826 (implicated_via_orthology)
Diseasesick sinus syndrome (implicated_via_orthology)

HCN4 SCN5A

2.01e-053772DOID:13884 (implicated_via_orthology)
DiseaseSick sinus syndrome

HCN4 SCN5A

2.01e-053772cv:C0037052
DiseaseFamilial sick sinus syndrome

HCN4 SCN5A

2.01e-053772cv:C0340491
Diseasesick sinus syndrome (is_implicated_in)

HCN4 SCN5A

6.69e-055772DOID:13884 (is_implicated_in)
DiseaseSick Sinus Syndrome

HCN4 SCN5A

1.00e-046772C0037052
DiseaseBrugada syndrome

HCN4 SCN5A

1.86e-048772cv:C1142166
DiseaseGastric Adenocarcinoma

BMPR1A BMPR1B ACVR2A

2.24e-0445773C0278701
DiseaseMarfan syndrome (implicated_via_orthology)

ACVR2A ACVR2B

2.98e-0410772DOID:14323 (implicated_via_orthology)
DiseaseCongenital myopathy (disorder)

SCN4A HACD1

4.36e-0412772C0270960
DiseaseBrugada Syndrome 1

HCN4 SCN5A

5.15e-0413772C4551804
DiseaseTremor, Rubral

NPC1 SCN8A

7.88e-0416772C0750940
DiseaseAtaxia, Appendicular

NPC1 SCN8A

7.88e-0416772C0750937
DiseaseAtaxia, Motor

NPC1 SCN8A

7.88e-0416772C0278161
DiseaseAbnormal coordination

NPC1 SCN8A

7.88e-0416772C0520966
Diseasefourth ventricle volume measurement

SCN7A ATP10D

7.88e-0416772EFO_0010303
DiseaseAtaxia, Truncal

NPC1 SCN8A

7.88e-0416772C0427190
DiseaseAtaxia, Sensory

NPC1 SCN8A

7.88e-0416772C0240991
Diseaseresponse to ketamine

SCN11A MROH2B LARGE1

7.91e-0469773EFO_0009748
DiseaseEye Abnormalities

BMPR1A BMPR1B

8.91e-0417772C0015393
Diseasesevere acute respiratory syndrome, COVID-19

HACD3 USP9X TSPAN7 UNC13C ADGRL3 ANAPC4

1.12e-03447776EFO_0000694, MONDO_0100096
DiseaseBrugada Syndrome (disorder)

HCN4 SCN5A

1.79e-0324772C1142166
DiseaseAtaxia

NPC1 SCN8A

1.94e-0325772C0004134
Diseasehearing impairment

TMC1 ADGRV1 USH2A

2.17e-0398773C1384666
Diseaseretinitis pigmentosa (implicated_via_orthology)

USH2A CNGB1

2.26e-0327772DOID:10584 (implicated_via_orthology)

Protein segments in the cluster

PeptideGeneStartEntry
FAIMVVFLLMWAPYN

CCRL2

241

O00421
AFFRWLYVAMLRMTE

ANAPC4

416

Q9UJX5
VVWVLFMIIGLFSMY

ACER1

61

Q8TDN7
AFLRIDMYAMGLVLW

ACVR2A

381

P27037
AFTWMFLEGVQLYIM

ADGRL3

941

Q9HAR2
MAYRHFWMLVLFVIF

ADGRV1

6126

Q8WXG9
IMADMYSFGLILWEV

BMPR1B

396

O00238
LLAGFYMFWTMIILL

ATP10D

366

Q9P241
LYGIIMNFSWLYTMI

NWD2

851

Q9ULI1
MRIFAVFIFMTYWHL

CD274

1

Q9NZQ7
RYMLMIFSAAFLVSW

KCNJ4

56

P48050
LLERLWYVMLEQFLM

ABCD1

321

P33897
MLDMGTLFTFRYHVW

LARGE1

616

O95461
YLAMLWRYKVTADFM

MDN1

2936

Q9NU22
FYMLTCIDMDWKVLT

HACD3

261

Q9P035
EMVMYSITVAFWLLN

MFF

321

Q9GZY8
EMWLLILVAYMFQRN

LIPM

16

Q5VYY2
FVMVYTVTWLFFGMI

KCNJ6

96

P48051
VSAWFIMLTYLFMLA

GPM6A

126

P51674
WELQMFFFMVFSLLY

OR4K2

21

Q8NGD2
LHYRWTMALMEEFFL

PDE1A

376

P54750
MDMFPLTWVFLALYF

NRP2

1

O60462
VDYLHLMLVAMKWLF

POLG

1106

P54098
LMLVAMKWLFEEFAI

POLG

1111

P54098
KFYVFMWLLADIISV

GDPD4

466

Q6W3E5
DFRFYWDLIMLLLMV

HCN3

91

Q9P1Z3
FRFYWDLTMLLLMVG

HCN4

261

Q9Y3Q4
QSYWLSFFMVMILFV

GPR160

181

Q9UJ42
IMWITYMAFLLVFFG

NPC1

271

O15118
FEYSVVFNMVLWIMI

ATP6AP2

301

O75787
YDTFWKHFIFVMMDI

GDE1

241

Q9NZC3
MYVKSLYWALAFMAV

KLRG2

256

A4D1S0
YLWTTFMAVIVGIFM

SLC1A7

96

O00341
ITLEGWVDIMYFVMD

CACNA1G

351

O43497
IISEWMGYFLLFESM

PRMT3

326

O60678
GWLVLAIAMVRFYME

HACD1

86

B0YJ81
IMADIYSFGLIIWEM

BMPR1A

426

P36894
VLWLMHFMAIIYTRL

UGCG

21

Q16739
FAIDWLSMCYMLTYI

FLVCR2

121

Q9UPI3
AALWLTILDFMDKYM

GBF1

1641

Q92538
DMTLTEFKFIWYMEY

COX15

136

Q7KZN9
GAMIVYWVLMSNFLF

SLC38A9

211

Q8NBW4
ILFWMFLSMYLVTVV

OR1D2

26

P34982
ILFWMFLSMYLVTVL

OR1D4

26

P47884
ILFWMFLSMYLVTVL

OR1D5

26

P58170
VFFVLILWMYLMILL

OR13C8

26

Q8NGS7
DSLKLAVFMWLMTYV

RTN3

956

O95197
EFYSELWFIVLMAML

USH2A

5036

O75445
YMMDDLELIGLDYLW

USP9X

761

Q93008
VFTYIFIMEMLLKWV

SCN4A

1071

P35499
LAMLRFVVMDYDWKS

PLCD4

696

Q9BRC7
TAFDMDTYMLQKLFW

SLC9C1

91

Q4G0N8
FTYVFVLEMLLKWVA

SCN5A

1246

Q14524
MLYYLWMLHSVTLFL

SCAMP2

151

O15127
LITEMYTVAWFVRDM

SP110

626

Q9HB58
RLSDKIFMLFWYIME

MROH2B

181

Q7Z745
SMWIFALTAGLFMYV

SLC39A6

686

Q13433
FLRWMYGVNMVLFIL

TMC1

191

Q8TDI8
FYLSVFFWMLTLGLM

ADGRF5

1096

Q8IZF2
FFWMLTLGLMLFYRL

ADGRF5

1101

Q8IZF2
WLSMASLVIFMQLRY

AMFR

286

Q9UKV5
FLRIDMYAMGLVLWE

ACVR2B

381

Q13705
LVQQPDMMYFILFLW

CLMN

971

Q96JQ2
DMMYFILFLWLLVYC

CLMN

976

Q96JQ2
LTNLMYVLWLFFVVM

CNGB1

651

Q14028
MMIISLAWLIFYYIQ

RNF149

211

Q8NC42
LLMYMNEEDAFWALV

USP6NL

196

Q92738
SEMFVILMLYLWFAI

ZDHHC22

181

Q8N966
MWTLFALDMKYALEE

UNC13C

1631

Q8NB66
FWMSVVIYTMLVLIF

PIEZO2

736

Q9H5I5
WLIMSSLMLLFLFTY

PSEN2

171

P49810
YSDLFAMIGTLFLWM

RHAG

206

Q02094
WLDFSVIMMAYITEF

SCN8A

196

Q9UQD0
SAWMLKLYAMFLTLV

TSPAN6

86

O43657
LVLAMALGWANMLYY

TRPV3

551

Q8NET8
TYIFILEMLLKWMAY

SCN7A

976

Q01118
LIMFIYAILGMNWFS

SCN11A

1506

Q9UI33
WMLKLYAMFLSLVFL

TSPAN7

86

P41732
MTMYLWLKLLAFGFA

PTPRC

1

P08575
LMYLVMVAAIAWEET

TM6SF1

121

Q9BZW5