Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionATP-dependent activity

MYH1 MYH2 MYH4 ATRX NSF MYO9A ABCA13 YTHDC2 BTAF1 IDE DNAH7 ABCA10 MYO5C MSH6 DNAH17 DDX43 AQR

5.02e-0661415317GO:0140657
GeneOntologyMolecularFunctionmicrofilament motor activity

MYH1 MYH2 MYH4 MYO9A MYO5C

1.01e-05381535GO:0000146
GeneOntologyMolecularFunctioncytoskeletal motor activity

MYH1 MYH2 MYH4 MYO9A DNAH7 MYO5C DNAH17

3.50e-051181537GO:0003774
GeneOntologyMolecularFunctionactin filament binding

MYH1 MYH2 MYH4 MYO9A ESPNL FMNL2 MYO5C FMNL3 ADSS1

6.54e-052271539GO:0051015
GeneOntologyMolecularFunctionSUMO binding

ZCCHC18 ZCCHC12 USP25

3.91e-04191533GO:0032183
GeneOntologyMolecularFunctioncalmodulin binding

MYH1 MYH2 MYH4 MYO5C PLCB1 TRPV6 AKT1 UNC13A

4.05e-042301538GO:0005516
GeneOntologyMolecularFunctioncatalytic activity, acting on a nucleic acid

ATRX DIS3L YTHDC2 BTAF1 DUS2 MSH6 ERI3 RNASET2 PCIF1 XRN1 DDX43 TRMT5 GEN1 AQR

4.51e-0464515314GO:0140640
GeneOntologyMolecularFunctionRNA polymerase II C-terminal domain phosphoserine binding

SCAF4 PCIF1

5.75e-0451532GO:1990269
GeneOntologyMolecularFunctionATP hydrolysis activity

MYH4 ATRX NSF ABCA13 YTHDC2 BTAF1 IDE DNAH7 ABCA10 DDX43 AQR

6.06e-0444115311GO:0016887
GeneOntologyMolecularFunction3'-5' RNA helicase activity

YTHDC2 AQR

8.57e-0461532GO:0034458
GeneOntologyMolecularFunctionribonucleoside triphosphate phosphatase activity

MYH4 RRAS2 ATRX NSF ABCA13 YTHDC2 BTAF1 IDE DNAH7 ABCA10 TUBB6 TUBB4A DDX43 AQR ADSS1

9.21e-0477515315GO:0017111
GeneOntologyMolecularFunctionmodification-dependent protein binding

ATRX L3MBTL2 CGAS IDE MSH6 PSME4 PLCG2

1.07e-032061537GO:0140030
GeneOntologyMolecularFunctionactin binding

MYH1 MYH2 MYH4 TRPM7 MYO9A ESPNL FMNL2 MYO5C FMNL3 DST ADSS1

1.19e-0347915311GO:0003779
GeneOntologyMolecularFunctiondynein light intermediate chain binding

RILPL1 DNAH7 DNAH17

1.26e-03281533GO:0051959
GeneOntologyCellularComponentmyosin complex

MYH1 MYH2 MYH4 MYO9A MYO5C

6.73e-05591515GO:0016459
GeneOntologyCellularComponentmuscle myosin complex

MYH1 MYH2 MYH4

1.93e-04161513GO:0005859
DomainPNMA

ZCCHC18 ZCCHC12 PNMA5 PNMA2

1.30e-06111514IPR026523
DomainPNMA

ZCCHC18 ZCCHC12 PNMA5 PNMA2

1.30e-06111514PF14893
DomainP-loop_NTPase

MYH1 MYH2 MYH4 RRAS2 SAMD9 ATRX NSF MYO9A ABCA13 YTHDC2 BTAF1 CMSS1 DNAH7 ABCA10 MYO5C MSH6 HS2ST1 DDX43 AQR NLRP13 ADSS1

4.79e-0684815121IPR027417
DomainMyosin_N

MYH1 MYH2 MYH4 MYO5C

5.23e-06151514PF02736
DomainMyosin_N

MYH1 MYH2 MYH4 MYO5C

5.23e-06151514IPR004009
DomainMyosin_head_motor_dom

MYH1 MYH2 MYH4 MYO9A MYO5C

1.31e-05381515IPR001609
DomainMYOSIN_MOTOR

MYH1 MYH2 MYH4 MYO9A MYO5C

1.31e-05381515PS51456
DomainMyosin_head

MYH1 MYH2 MYH4 MYO9A MYO5C

1.31e-05381515PF00063
DomainMYSc

MYH1 MYH2 MYH4 MYO9A MYO5C

1.31e-05381515SM00242
DomainMyosin-like_IQ_dom

MYH1 MYH2 MYH4 MYO5C

1.45e-05191514IPR027401
Domain-

MYH1 MYH2 MYH4 MYO5C

1.45e-051915144.10.270.10
DomainARM-type_fold

PPP4R1 GPRASP1 APC ARFGEF2 BTAF1 FMNL2 FMNL3 SF3B1 PSME4 XPO5 AOPEP UTP20

2.07e-0533915112IPR016024
DomainPeptidase_M16_M

NRDC IDE

6.49e-0521512PF16187
DomainPIEZO

PIEZO1 PIEZO2

6.49e-0521512PF15917
DomainPeptidase_M16_M

NRDC IDE

6.49e-0521512IPR032632
DomainPiezo

PIEZO1 PIEZO2

6.49e-0521512IPR027272
DomainPiezo_RRas_bdg

PIEZO1 PIEZO2

6.49e-0521512PF12166
DomainPiezo_RRas-bd_dom

PIEZO1 PIEZO2

6.49e-0521512IPR031334
DomainPiezo_dom

PIEZO1 PIEZO2

6.49e-0521512IPR031805
Domain-

PPP4R1 GPRASP1 APC ARFGEF2 BTAF1 SF3B1 PSME4 XPO5 UTP20

8.26e-0522215191.25.10.10
DomainHEAT_REPEAT

PPP4R1 BTAF1 SF3B1 PSME4 UTP20

2.56e-04701515PS50077
DomainIQ

MYH1 MYH2 MYH4 MYO9A MYO5C

2.74e-04711515PF00612
DomainARM-like

PPP4R1 GPRASP1 APC ARFGEF2 BTAF1 SF3B1 PSME4 XPO5 UTP20

3.57e-042701519IPR011989
DomainMyosin_tail_1

MYH1 MYH2 MYH4

3.87e-04181513PF01576
DomainMyosin_tail

MYH1 MYH2 MYH4

3.87e-04181513IPR002928
DomainIQ

MYH1 MYH2 MYH4 MYO9A MYO5C

5.05e-04811515SM00015
DomainHEAT

PPP4R1 BTAF1 SF3B1 UTP20

6.06e-04481514PF02985
DomainDUF4371

ZMYM1 ZMYM6

6.39e-0451512IPR025398
DomainDUF4371

ZMYM1 ZMYM6

6.39e-0451512PF14291
DomainIQ_motif_EF-hand-BS

MYH1 MYH2 MYH4 MYO9A MYO5C

8.18e-04901515IPR000048
DomainIQ

MYH1 MYH2 MYH4 MYO9A MYO5C

9.49e-04931515PS50096
Domain-

RRAS2 SAMD9 ATRX NSF ABCA13 YTHDC2 BTAF1 CMSS1 DNAH7 ABCA10 MSH6 HS2ST1 DDX43 AQR NLRP13

1.07e-03746151153.40.50.300
DomainHEAT

PPP4R1 BTAF1 SF3B1 UTP20

1.24e-03581514IPR000357
DomainPept_M16_Zn_BS

NRDC IDE

1.33e-0371512IPR001431
DomainPept_M16_dom

NRDC IDE

1.33e-0371512IPR011237
DomainMetalloenz_LuxS/M16

NRDC IDE

1.33e-0371512IPR011249
DomainPeptidase_M16

NRDC IDE

1.33e-0371512PF00675
DomainZnf_MYM

ZMYM1 ZMYM6

1.33e-0371512IPR010507
DomainPeptidase_M16_C

NRDC IDE

1.33e-0371512IPR007863
DomainPeptidase_M16_C

NRDC IDE

1.33e-0371512PF05193
DomainPept_M16_N

NRDC IDE

1.33e-0371512IPR011765
Domain-

NRDC IDE

1.33e-03715123.30.830.10
DomainINSULINASE

NRDC IDE

1.33e-0371512PS00143
Domainzf-FCS

ZMYM1 ZMYM6

1.33e-0371512PF06467
DomainTRASH_dom

ZMYM1 ZMYM6

1.76e-0381512IPR011017
DomainTRASH

ZMYM1 ZMYM6

1.76e-0381512SM00746
DomainDrf_GBD

FMNL2 FMNL3

2.25e-0391512PF06371
DomainDrf_FH3

FMNL2 FMNL3

2.25e-0391512PF06367
DomainFH3_dom

FMNL2 FMNL3

2.25e-0391512IPR010472
DomainGTPase-bd

FMNL2 FMNL3

2.25e-0391512IPR010473
DomainDrf_FH3

FMNL2 FMNL3

2.25e-0391512SM01139
DomainDrf_GBD

FMNL2 FMNL3

2.25e-0391512SM01140
Pubmed

Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein.

PPP4R1 SAMD9 ATRX NRDC APC YTHDC2 BTAF1 ECE1 TUBB6 TGM2 FREM2 DST PSME4 TBK1 XRN1 MTR AQR MAN1B1

7.64e-106501541838777146
Pubmed

Direct evidence for the action of phosphatidylinositol (3,4,5)-trisphosphate-mediated signal transduction in the 2-cell mouse embryo.

PLCB1 AKT1 AKT2 PLCG2

1.28e-087154417634444
Pubmed

E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins.

CFAP47 MYH1 MYH4 PCDHB12 NTMT1 AGPS FMNL2 MSH6 FREM2 LOXHD1 DST TBK1 PCIF1 PKHD1 UTP20 PLXNB3 PSMG4

3.34e-087361541729676528
Pubmed

GASP-2 overexpressing mice exhibit a hypermuscular phenotype with contrasting molecular effects compared to GASP-1 transgenics.

GPRASP1 MYH1 MYH2 MYH4

4.58e-089154431960486
Pubmed

Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.

TRIM46 RABEP2 GPRASP1 WDR7 NSF APC ARHGAP39 BCL9 PEX5L TUBB6 ZNF263 SF3B1 DST GPR158 KIAA1217 TBK1 PLCB1 NEURL4 UNC13A

5.97e-089631541928671696
Pubmed

Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.

AKAP6 PPP4R1 GPRASP1 ZCCHC12 ATRX TRPM7 DIS3L USP25 APC ARFGEF2 RILPL1 FMNL2 TUBB4A SF3B1 DST APPL2 SACS GLUD1 PNMA2 PDZD8 GEN1 PLXNB3

6.04e-0812851542235914814
Pubmed

Transition of myosin heavy chain isoforms in human laryngeal abductors following denervation.

MYH1 MYH2 MYH4

8.51e-083154326059207
Pubmed

Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.

RRAS2 L3MBTL2 CENPC MYO9A CGAS CASP8 AGPS CMSS1 ERLIN1 TUBB6 TGM2 MSH6 GTF2H1 SF3B1 DST PSME4 XRN1 UTP20 PYGL DDX43 PLCG2 AQR

1.47e-0713531542229467282
Pubmed

LRRC31 inhibits DNA repair and sensitizes breast cancer brain metastasis to radiation therapy.

MYH4 ARFGEF2 BTAF1 MYO5C MSH6 XPO5 XRN1 UTP20 NEURL4

3.22e-07202154933005030
Pubmed

Smooth muscle myosin light chain kinase expression in cardiac and skeletal muscle.

MYH1 MYH2 MYH4

3.39e-074154311029314
Pubmed

Modulation of skeletal muscle fiber type by mitogen-activated protein kinase signaling.

MYH1 MYH2 MYH4

3.39e-074154318417546
Pubmed

Comparative sequence analysis of the complete human sarcomeric myosin heavy chain family: implications for functional diversity.

MYH1 MYH2 MYH4

3.39e-074154310388558
Pubmed

A human YAC transgene rescues craniofacial and neural tube development in PDGFRalpha knockout mice and uncovers a role for PDGFRalpha in prenatal lung growth.

MYH1 MYH2 MYH4

3.39e-074154311023856
Pubmed

Regulation of the Ca(2+) channel TRPV6 by the kinases SGK1, PKB/Akt, and PIKfyve.

PIKFYVE TRPV6 AKT1

3.39e-074154320041238
Pubmed

Developmental pattern of mouse skeletal myosin heavy chain gene transcripts in vivo and in vitro.

MYH1 MYH2 MYH4

8.46e-07515433829126
Pubmed

Myosin heavy chain isoforms of the murine masseter muscle during pre- and post-natal development.

MYH1 MYH2 MYH4

8.46e-075154312919077
Pubmed

Detection of Gene and Protein Expression in Mouse Embryos and Tissue Sections.

MYH1 MYH2 MYH4

8.46e-075154330737693
Pubmed

Sequential accumulation of mRNAs encoding different myosin heavy chain isoforms during skeletal muscle development in vivo detected with a recombinant plasmid identified as coding for an adult fast myosin heavy chain from mouse skeletal muscle.

MYH1 MYH2 MYH4

8.46e-07515436196357
Pubmed

Distinct myogenic programs of embryonic and fetal mouse muscle cells: expression of the perinatal myosin heavy chain isoform in vitro.

MYH1 MYH2 MYH4

1.69e-06615431728586
Pubmed

A hypoplastic model of skeletal muscle development displaying reduced foetal myoblast cell numbers, increased oxidative myofibres and improved specific tension capacity.

MYH1 MYH2 MYH4

1.69e-066154320417199
Pubmed

Organization of human and mouse skeletal myosin heavy chain gene clusters is highly conserved.

MYH1 MYH2 MYH4

1.69e-066154310077619
Pubmed

A role for Insulin-like growth factor 2 in specification of the fast skeletal muscle fibre.

MYH1 MYH2 MYH4

1.69e-066154317559643
Pubmed

Spatial and temporal changes in myosin heavy chain gene expression in skeletal muscle development.

MYH1 MYH2 MYH4

1.69e-066154310588881
Pubmed

Gene expression analysis of the embryonic subplate.

ZCCHC18 RRAS2 ZCCHC12 MYO9A CASP8 IDE CITED2 LRRN3

2.85e-06196154821862448
Pubmed

A fast Myosin super enhancer dictates muscle fiber phenotype through competitive interactions with Myosin genes.

MYH1 MYH2 MYH4

2.94e-067154335210422
Pubmed

ANKK1 is found in myogenic precursors and muscle fibers subtypes with glycolytic metabolism.

MYH1 MYH2 MYH4

2.94e-067154329758057
Pubmed

Diversity in transcriptional start site selection and alternative splicing affects the 5'-UTR of mouse striated muscle myosin transcripts.

MYH1 MYH2 MYH4

2.94e-067154316819597
Pubmed

Identifying biological pathways that underlie primordial short stature using network analysis.

RRAS2 NSF YTHDC2 BTAF1 AGPS ERLIN1 SCAF4 MYO5C TUBB6 SF3B1 DST SACS TBK1 GLUD1 UTP20 NEURL4 AQR

3.26e-0610241541724711643
Pubmed

Cell lineage- and expression-based inference of the roles of forkhead box transcription factor Foxc2 in craniofacial development.

MYH1 MYH2 MYH4

4.69e-068154333667029
Pubmed

A Tcf4-positive mesodermal population provides a prepattern for vertebrate limb muscle patterning.

MYH1 MYH2 MYH4

4.69e-068154314667415
Pubmed

Neuromuscular junction immaturity and muscle atrophy are hallmarks of the ColQ-deficient mouse, a model of congenital myasthenic syndrome with acetylcholinesterase deficiency.

MYH1 MYH2 MYH4

4.69e-068154326993635
Pubmed

Appl1 is dispensable for mouse development, and loss of Appl1 has growth factor-selective effects on Akt signaling in murine embryonic fibroblasts.

APPL2 AKT1 AKT2

4.69e-068154320040596
Pubmed

Identification and characterization of a set of conserved and new regulators of cytoskeletal organization, cell morphology and migration.

FMNL2 FMNL3 PDZD8 ZMYM6

8.05e-0629154421834987
Pubmed

Autophagy controls neonatal myogenesis by regulating the GH-IGF1 system through a NFE2L2- and DDIT3-mediated mechanism.

MYH1 MYH2 MYH4 AKT1

1.06e-0531154430081710
Pubmed

Defining the human deubiquitinating enzyme interaction landscape.

GPRASP1 MYH2 MYH4 SUPT3H NRDC NSF USP25 APC YTHDC2 CMSS1 TBK1 PYGL SRPX NEURL4 ZMYM6 AQR

1.08e-0510051541619615732
Pubmed

The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.

SUPT3H ATRX NSF PIEZO1 APC YTHDC2 ARHGAP39 CMSS1 ERLIN1 SCAF4 TUBB6 MSH6 GTF2H1 DST APPL2 XRN1 UTP20 INTS9 AQR MAN1B1

1.10e-0514971542031527615
Pubmed

Genome-wide CRISPR screens identify novel regulators of wild-type and mutant p53 stability.

PPP4R1 ATRX MYO9A APC PIKFYVE PIAS4 TUBB4A ALDH1A2 KIAA1217 TBK1 MTR ZMYM6

1.32e-055881541238580884
Pubmed

Platelet-derived growth factor CC-mediated neuroprotection against HIV Tat involves TRPC-mediated inactivation of GSK 3beta.

TRPC1 AKT1 AKT2

1.37e-0511154323077641
Pubmed

Deletion of the protein kinase A/protein kinase G target SMTNL1 promotes an exercise-adapted phenotype in vascular smooth muscle.

MYH1 MYH2 MYH4

1.37e-0511154318310078
Pubmed

Modulation of contractile protein gene expression in fetal murine crural muscles: emergence of muscle diversity.

MYH1 MYH2 MYH4

1.37e-051115438136524
Pubmed

Calcineurin is necessary for the maintenance but not embryonic development of slow muscle fibers.

MYH1 MYH2 MYH4

1.37e-0511154316024798
Pubmed

Extracellular matrix protein composition dynamically changes during murine forelimb development.

MYH1 MYH2 MYH4

1.37e-0511154338303699
Pubmed

The histone code reader Spin1 controls skeletal muscle development.

MYH1 MYH2 MYH4

1.37e-0511154329168801
Pubmed

Myosin heavy chain-embryonic regulates skeletal muscle differentiation during mammalian development.

MYH1 MYH2 MYH4 AKT1

1.37e-0533154432094117
Pubmed

Appl1 is dispensable for Akt signaling in vivo and mouse T-cell development.

APPL2 AKT1 AKT2

1.82e-0512154320665729
Pubmed

Different functions of AKT1 and AKT2 in molecular pathways, cell migration and metabolism in colon cancer cells.

AKT1 AKT2

1.95e-052154227878243
Pubmed

BAY 1125976, a selective allosteric AKT1/2 inhibitor, exhibits high efficacy on AKT signaling-dependent tumor growth in mouse models.

AKT1 AKT2

1.95e-052154227699769
Pubmed

Identification of proteins that interact with murine cytomegalovirus early protein M112-113 in brain.

ZCCHC18 ZCCHC12

1.95e-052154222340173
Pubmed

Isoform-Specific Role of Akt in Oral Squamous Cell Carcinoma.

AKT1 AKT2

1.95e-052154231252679
Pubmed

Myosin heavy chains IIa and IId are functionally distinct in the mouse.

MYH1 MYH2

1.95e-05215429585413
Pubmed

Akt1 is critical for acute inflammation and histamine-mediated vascular leakage.

AKT1 AKT2

1.95e-052154219622728
Pubmed

Expression of AKT1 along with AKT2 in granulosa-lutein cells of hyperandrogenic PCOS patients.

AKT1 AKT2

1.95e-052154228271235
Pubmed

[Feeling the pressure? Identification of two proteins activated by mechanical forces].

PIEZO1 PIEZO2

1.95e-052154221299953
Pubmed

Role of Akt in cardiac growth and metabolism.

AKT1 AKT2

1.95e-052154217019809
Pubmed

Repression of E1AF transcriptional activity by sumoylation and PIASy.

ETV4 PIAS4

1.95e-052154217585876
Pubmed

Piezo1 channel causes lens sclerosis via transglutaminase 2 activation.

PIEZO1 TGM2

1.95e-052154237951336
Pubmed

Piezo1 expression in chondrocytes controls endochondral ossification and osteoarthritis development.

PIEZO1 PIEZO2

1.95e-052154238395992
Pubmed

Knockout of Akt1/2 suppresses the metastasis of human prostate cancer cells CWR22rv1 in vitro and in vivo.

AKT1 AKT2

1.95e-052154233377281
Pubmed

Differential expression of PIEZO1 and PIEZO2 mechanosensitive channels in ocular tissues implicates diverse functional roles.

PIEZO1 PIEZO2

1.95e-052154237820892
Pubmed

Akt2 mRNA is highly expressed in embryonic brown fat and the AKT2 kinase is activated by insulin.

AKT1 AKT2

1.95e-05215429620559
Pubmed

Mechanisms of mechanotransduction and physiological roles of PIEZO channels.

PIEZO1 PIEZO2

1.95e-052154239251883
Pubmed

Akt1 and Akt2 differently regulate muscle creatine kinase and myogenin gene transcription in insulin-induced differentiation of C2C12 myoblasts.

AKT1 AKT2

1.95e-052154211861503
Pubmed

Akt regulates basic helix-loop-helix transcription factor-coactivator complex formation and activity during neuronal differentiation.

AKT1 AKT2

1.95e-052154212808085
Pubmed

Analysis of mouse conceptuses with uniparental duplication/deficiency for distal chromosome 12: comparison with chromosome 12 uniparental disomy and implications for genomic imprinting.

MYH1 MYH2

1.95e-052154216575183
Pubmed

Immunolocalization of the mechanogated ion channels PIEZO1 and PIEZO2 in human and mouse dental pulp and periodontal ligament.

PIEZO1 PIEZO2

1.95e-052154237975162
Pubmed

Impaired expression and insulin-stimulated phosphorylation of Akt-2 in muscle of obese patients with atypical diabetes.

AKT1 AKT2

1.95e-052154215010337
Pubmed

Reducing Akt2 in retinal pigment epithelial cells causes a compensatory increase in Akt1 and attenuates diabetic retinopathy.

AKT1 AKT2

1.95e-052154236229454
Pubmed

Akt2 regulates cardiac metabolism and cardiomyocyte survival.

AKT1 AKT2

1.95e-052154216950770
Pubmed

Akt isoforms differentially regulate neutrophil functions.

AKT1 AKT2

1.95e-052154220332370
Pubmed

Transduction of Repetitive Mechanical Stimuli by Piezo1 and Piezo2 Ion Channels.

PIEZO1 PIEZO2

1.95e-052154228636944
Pubmed

Molecular cloning of the akt oncogene and its human homologues AKT1 and AKT2: amplification of AKT1 in a primary human gastric adenocarcinoma.

AKT1 AKT2

1.95e-05215423037531
Pubmed

High-intensity muscle contraction-mediated increases in Akt1 and Akt2 phosphorylation do not contribute to mTORC1 activation and muscle protein synthesis.

AKT1 AKT2

1.95e-052154232078465
Pubmed

Defining Akt actions in muscle differentiation.

AKT1 AKT2

1.95e-052154223076793
Pubmed

Function of Akt/PKB signaling to cell motility, invasion and the tumor stroma in cancer.

AKT1 AKT2

1.95e-052154219110052
Pubmed

Loss of Akt1 or Akt2 delays mammary tumor onset and suppresses tumor growth rate in MTB-IGFIR transgenic mice.

AKT1 AKT2

1.95e-052154223919516
Pubmed

Cutaneous human papillomaviruses down-regulate AKT1, whereas AKT2 up-regulation and activation associates with tumors.

AKT1 AKT2

1.95e-052154217804734
Pubmed

Lack of AKT in adipocytes causes severe lipodystrophy.

AKT1 AKT2

1.95e-052154227408773
Pubmed

Isoform-specific requirement for Akt1 in the developmental regulation of cellular metabolism during lactation.

AKT1 AKT2

1.95e-052154217141631
Pubmed

PI3K/AKT Signaling in Breast Cancer Molecular Subtyping and Lymph Node Involvement.

AKT1 AKT2

1.95e-052154231781306
Pubmed

Piezo channels: from structure to function.

PIEZO1 PIEZO2

1.95e-052154225037583
Pubmed

Growth and muscle defects in mice lacking adult myosin heavy chain genes.

MYH1 MYH4

1.95e-05215429382868
Pubmed

Postnatal myosin heavy chain isoform expression in normal mice and mice null for IIb or IId myosin heavy chains.

MYH1 MYH4

1.95e-052154211150240
Pubmed

Myosin heavy chain composition of the human genioglossus muscle.

MYH1 MYH2

1.95e-052154222337492
Pubmed

A strategy to identify protein-N-myristoylation-dependent phosphorylation reactions of cellular proteins by using Phos-tag SDS-PAGE.

FMNL2 FMNL3

1.95e-052154231751425
Pubmed

Akt-1 and Akt-2 Differentially Regulate the Development of Experimental Autoimmune Encephalomyelitis by Controlling Proliferation of Thymus-Derived Regulatory T Cells.

AKT1 AKT2

1.95e-052154230692211
Pubmed

Distinct actions of akt1 on skeletal architecture and function.

AKT1 AKT2

1.95e-052154224663486
Pubmed

rac regulates its effector phospholipase Cgamma2 through interaction with a split pleckstrin homology domain.

AKT1 PLCG2

1.95e-052154218728011
Pubmed

Akt1 and akt2 play distinct roles in the initiation and metastatic phases of mammary tumor progression.

AKT1 AKT2

1.95e-052154219491266
Pubmed

Akt1 and Akt2 are required for alphabeta thymocyte survival and differentiation.

AKT1 AKT2

1.95e-052154217609365
Pubmed

Identification of functional domains in AKT responsible for distinct roles of AKT isoforms in pressure-stimulated cancer cell adhesion.

AKT1 AKT2

1.95e-052154217825284
Pubmed

Depletion of Akt1 and Akt2 Impairs the Repair of Radiation-Induced DNA Double Strand Breaks via Homologous Recombination.

AKT1 AKT2

1.95e-052154231847370
Pubmed

Unique roles of Akt1 and Akt2 in IGF-IR mediated lung tumorigenesis.

AKT1 AKT2

1.95e-052154226654940
Pubmed

The role of PIEZO ion channels in the musculoskeletal system.

PIEZO1 PIEZO2

1.95e-052154236717101
Pubmed

Quantitative analysis of anti-apoptotic function of Akt in Akt1 and Akt2 double knock-out mouse embryonic fibroblast cells under normal and stressed conditions.

AKT1 AKT2

1.95e-052154216923802
Pubmed

Role of AMPK and Akt in triple negative breast cancer lung colonization.

AKT1 AKT2

1.95e-052154233839456
Pubmed

Akt1 and Akt2: differentiating the aktion.

AKT1 AKT2

1.95e-052154221432781
Pubmed

Molecular alterations in AKT and its protein activation in human lung carcinomas.

AKT1 AKT2

1.95e-052154222748472
Pubmed

Akt deficiency impairs normal cell proliferation and suppresses oncogenesis in a p53-independent and mTORC1-dependent manner.

AKT1 AKT2

1.95e-052154217045205
Pubmed

Different pathways regulate expression of the skeletal myosin heavy chain genes.

MYH1 MYH2

1.95e-052154211551968
Pubmed

A Plug-and-Latch Mechanism for Gating the Mechanosensitive Piezo Channel.

PIEZO1 PIEZO2

1.95e-052154232142647
GeneFamilyParaneoplastic Ma antigens

ZCCHC18 ZCCHC12 PNMA5 PNMA2

2.50e-0711974671
GeneFamilyMyosin heavy chains

MYH1 MYH2 MYH4

6.50e-05159731098
GeneFamilyZinc fingers MYM-type

ZMYM1 ZMYM6

4.21e-04697286
GeneFamilyTransient receptor potential cation channels

TRPM7 TRPC1 TRPV6

4.45e-0428973249
GeneFamilyATP binding cassette subfamily A

ABCA13 ABCA10

2.49e-0314972805
CoexpressionRODRIGUES_THYROID_CARCINOMA_ANAPLASTIC_UP

RRAS2 SAMD9 ATRX APC ARFGEF2 BTAF1 AGPS CMSS1 ERLIN1 TGM2 MSH6 SF3B1 GPR158 PNMA2 XRN1 PLCB1 TRMT5

1.27e-0672115417M10237
CoexpressionMANNO_MIDBRAIN_NEUROTYPES_HGABA

AKAP6 TRIM46 GPRASP1 ZCCHC12 SLC16A9 ATRX APC PEX5L FMNL2 CITED2 FSIP2 LRRN3 FAT2 PIEZO2 GPR158 CSAD PNMA2 CATSPERG SVOP UNC13A

8.03e-06110615420M39071
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_3|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

TIGD7 MYO9A ABCA13 TRPC1 BCO1 FSIP2 DNAH17 AKT2

5.76e-08151154816fc903fc71e25717b9908416f0bcd29c0a65a61
ToppCelldroplet-Lung-3m-Epithelial-airway_epithelial-neuroendocrine_cell|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ZCCHC12 ETV4 PEX5L ALDH1A2 PIEZO2 GPR158 PNMA2 UNC13A

2.63e-071841548e0e5a553fb8c0947679634396d20c2ca8455b932
ToppCelldroplet-Lung-3m-Epithelial-airway_epithelial-neuroendocrine_cell-neuroendocrine|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ZCCHC12 ETV4 PEX5L ALDH1A2 PIEZO2 GPR158 PNMA2 UNC13A

2.63e-071841548c3b848e1438a84b3fac8a4e40f3db478cc84d970
ToppCell(5)_Fibroblasts-(5)_Fibroblast-C_(Myofibroblast)|(5)_Fibroblasts / Lung cell shreds - cell class (v4) and cell subclass (v4)

MAOB OLFML3 ADAMTS12 CITED2 TGM2 LRRN3 PIEZO2 DST

3.36e-07190154871e112dfb8c3190fe0286b45a046ea789eb6a8db
ToppCellwk_20-22-Mesenchymal-Fibroblast-intermediate_fibro|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

MAOB ABCA10 OLFML3 ADAMTS12 ALDH1A2 PIEZO2 DST SRPX

4.96e-072001548d769723f8fcb37d9b86589e0c41c1d7f16393cfe
ToppCellmild|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

SAMD9 ATRX CENPC CASP8 BTAF1 SF3B1 XRN1 PLCG2

4.96e-07200154812f1685ce8f218433068e090c9d839cd5a1910bf
ToppCelldroplet-Heart-nan-3m|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

AKAP6 GPRASP1 ATRX TRPM7 MYO9A PSME4 XRN1

2.72e-061761547749b47eac5436fa34e0d243ffbc6f1897f4e431e
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_1|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

MYO9A ABCA13 EML6 DNAH7 ALDH1A2 PKHD1 AKT2

3.65e-061841547da06ff24ee2b2cf4715fdfce43030b2da9e0aaf8
ToppCellGlobus_pallidus-Neuronal|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

TRIM46 GPRASP1 NSF PAK6 GPR158 SVOP UNC13A

4.51e-061901547416de85d8841dac883faa6f5339b2fb461a09e82
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

MYO9A ABCA13 EML6 DNAH7 ALDH1A2 PKHD1 PLCB1

4.67e-061911547d0e9afe7b6334dd515d3e68892efdc76347a55e5
ToppCellPosterior_cortex-Neuronal|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

GPRASP1 ATRX NSF MYO9A PAK6 SVOP UNC13A

5.00e-061931547b4989e3436e84dbec3789b46057e0f7a0ebf09d4
ToppCellPCW_10-12-Mesenchymal-Mesenchymal_fibroblastic-mes_immature_COL13A1^pos_fibro1_(4)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

OLFML3 ADAMTS12 CITED2 IL1RAPL1 ALDH1A2 PIEZO2 DST

5.17e-06194154771d3c7448b1734de54187f902f65649f9283bd4c
ToppCell367C-Fibroblasts-Fibroblast-C_(Myofibroblast)-|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

MAOB OLFML3 CITED2 TGM2 LRRN3 PIEZO2 DST

5.53e-0619615476730743cf088c419ccc2d28765769fc09d3ba6a7
ToppCell367C-Fibroblasts-Fibroblast-C_(Myofibroblast)|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

MAOB OLFML3 CITED2 TGM2 LRRN3 PIEZO2 DST

5.53e-06196154721dab89f3699037138a9c7a0e4dc98739a9fad9c
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Glial-Neuronal-Oligodendrocyte-Oligodendrocyte-F|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

PEX5L IL1RAPL1 TUBB4A AOPEP DNAH17 PLXNB3 SEC14L5

6.31e-062001547829978708463a7459fe1041bd90196775bc4b531
ToppCellPND28-Epithelial-Epithelial_Airway-Neurosecretory-Secretory-Secretory_mature|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CFAP47 BPIFB1 FETUB ALDH1A2 PNMA2 PKHD1

1.15e-0514515469b69bfdbf91ef197b4c483617aa67498d9d2cd79
ToppCellPND28-Epithelial-Epithelial_Airway-Neurosecretory-Secretory|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CFAP47 BPIFB1 FETUB ALDH1A2 PNMA2 PKHD1

1.15e-05145154631af9fce1dcd7e8ae1604476598e099232017ee9
ToppCellPND28-Epithelial-Epithelial_Airway-Neurosecretory|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CFAP47 BPIFB1 FETUB ALDH1A2 PNMA2 PKHD1

1.15e-05145154676f0cde9acdc3ad5948c007dccf312665972c9e6
ToppCellE16.5-samps-Mesenchymal-Matrix_fibroblast-_fetal-matrix_-_immature_3|E16.5-samps / Age Group, Lineage, Cell class and subclass

YTHDC2 TUBB6 LRRN3 PNMA2 ZMYM1 ZMYM6

1.34e-051491546651494e84be03dc7b061ebdfa91756a1c507b9b4
ToppCell10x5'-Liver-Myeloid_Mac-Intestinal_macrophages|Liver / Manually curated celltypes from each tissue

SLC16A9 ESPNL PIEZO2 DST KIAA1217 PNMA2

1.74e-0515615469a897fc79c4fae94c5f2e9012d65297f9225e5e3
ToppCellPCW_07-8.5-Epithelial-Epithelial_ciliated-epi_ciliated_(14)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

CFAP47 DNAH7 MYO5C LRRC9 FREM2 PKHD1

2.38e-0516515460c714e852f912b5749de4cb0895406673979b2e6
ToppCellPCW_07-8.5-Epithelial-Epithelial_ciliated|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

CFAP47 DNAH7 MYO5C LRRC9 FREM2 PKHD1

2.38e-05165154682530f96aaefe28a13bad0474bbad043f127a86c
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_3|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

MYO9A ABCA13 FSIP2 DNAH17 PKHD1 AKT2

2.82e-0517015465d5f208682be21ed58320f5fc083a7898f8712da
ToppCellE18.5-Epithelial-Epithelial_Airway-Neurosecretory-PNEC-PNEC_mature|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ZCCHC18 ZCCHC12 EML6 ZNF2 TUBB4A DNAH17

3.21e-051741546742c73c9e090848b464323cb17579b86658c6792
ToppCell5'-GW_trimst-1.5-SmallIntestine-Epithelial-neuro-epithelial-K_cells_(GIP+)|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MYH1 MYH4 ABCA10 BCO1 PLCG2 SEC14L5

3.21e-0517415463503c7dec498597f76a86dbd5e4bb2311e743bde
ToppCellE18.5-Epithelial-Epithelial_Airway-Neurosecretory-PNEC|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ZCCHC18 ZCCHC12 EML6 ZNF2 TUBB4A DNAH17

3.21e-0517415467fed9722e64c60843092f2ba71256e3043011ef6
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

MYO9A ABCA13 EML6 ALDH1A2 DNAH17 PKHD1

3.42e-051761546327a3e81b724252e36d786de92a3ffd721ea6d7b
ToppCell356C-Fibroblasts-Fibroblast-G|356C / Donor, Lineage, Cell class and subclass (all cells)

MAOB PCDHB12 TGM2 PIEZO2 DST SEC14L5

3.53e-0517715468220cc2fc0ee8764a67a3be51d75248be2453040
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_1|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

MYO9A ABCA13 EML6 ALDH1A2 DNAH17 PKHD1

3.53e-051771546da8802a6351d3e510822f82e2fde8a4314a2216e
ToppCell356C-Fibroblasts-Fibroblast-G-|356C / Donor, Lineage, Cell class and subclass (all cells)

MAOB PCDHB12 TGM2 PIEZO2 DST SEC14L5

3.53e-0517715467617270f49cd6b7ba66db72d20560cee985012b2
ToppCell5'-Adult-LargeIntestine-Endothelial-lymphatic_endothelial-LEC1_(ACKR4+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ADAMTS12 TUBB6 TGM2 ALDH1A2 PIEZO2 PLXNB3

3.53e-051771546b1775e05c28883a15c56628028770bc59d3233fb
ToppCellE16.5-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT1-AT1_prolif|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MAOB DIS3L IDE MYO5C FMNL3 AKT2

4.00e-051811546f6629fa71bb94405f523f63a9264cacf6d15c5f4
ToppCellChildren_(3_yrs)-Immune-enucleated_erythrocyte-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

FBXW12 SLC30A1 KCTD17 MSH6 PCIF1 TRMT5

4.00e-051811546c029cecbd7182c70b9893d8c86f334c16291a0db
ToppCellTCGA-Thymus-Primary_Tumor-Thymoma-Type_B3-4|TCGA-Thymus / Sample_Type by Project: Shred V9

MYH1 MYH2 MYH4 BCO1 NLRP13

4.03e-05110154556e93e8d0d6232ab9090f685e5e4803ef79b2567
ToppCelldroplet-Limb_Muscle-nan-21m-Macroglial-nan|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PCDHB12 ARHGAP39 PEX5L IL1RAPL1 ALDH1A2 PLXNB3

4.13e-051821546a512863304fad80acaab60a8c6107eb7c9cbac99
ToppCell3'-GW_trimst-1.5-SmallIntestine-Neuronal-neurons_A-Branch_A4_(IN)|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

AKAP6 TUBB4A PNMA2 MED12L SVOP UNC13A

4.13e-051821546be32b5b8153c1053cbb55f1fccfa27c3ee97c1e1
ToppCellPBMC_fresh-frozen-Severe-critical_convalescent_d42-56-Lymphocytic-Lymphocytic_B-B_cell-B_c04-SOX5-TNFRSF1B|Severe-critical_convalescent_d42-56 / Compartment, severity and other cell annotations on 10x 3' data (130k)

RABEP2 PIKFYVE DUS2 TUBB6 PLCG2 GEN1

4.13e-0518215469c120ddd109103ef6fac9c32b84d16a7624d0580
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

MYO9A ABCA13 ALDH1A2 DNAH17 PKHD1 AKT2

4.25e-05183154692fbd83a9d13ee91065cbd479fb298f1fd564568
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYH1 ABCA13 FREM2 PIEZO2 LOXHD1 PKHD1

4.39e-0518415462cbed6462fea2622871bb7e49b0df3d984239281
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYH1 ABCA13 FREM2 PIEZO2 LOXHD1 PKHD1

4.39e-051841546ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYH1 ABCA13 FREM2 PIEZO2 LOXHD1 PKHD1

4.39e-0518415462b19a8c5f823e00812908b23e66bb4e563278aff
ToppCelldroplet-Lung-immune-endo-depleted-3m-Epithelial-lung_neuroendocrine_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ZCCHC12 ETV4 PEX5L ALDH1A2 GPR158 PNMA2

4.52e-05185154630263c558ee331e0879abcf8b4c2427ff05f9fe7
ToppCelldroplet-Limb_Muscle-Pre-Sort-18m-Macroglial-unknown|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ARHGAP39 PEX5L IL1RAPL1 FREM2 LRRN3 PNMA2

4.52e-05185154611c147f3f5570c4761d2bcff3bad28146b4a5861
ToppCelldroplet-Lung-immune-endo-depleted-3m-Epithelial-Neuroendocrine|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ZCCHC12 ETV4 PEX5L ALDH1A2 GPR158 PNMA2

4.52e-0518515461b000ca11970db8f347eb97ff44605d562aea70a
ToppCellHippocampus-Neuronal-Excitatory-eN2(Slc17a7_Slc17a6)-Slc17a6|Hippocampus / BrainAtlas - Mouse McCarroll V32

CCDC192 MYH2 MYO5C PNMA5 TRPV6

4.59e-0511315456f270b7e59c18243e876311df721e948ce21e850
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

MYO9A ABCA13 DNAH7 PKHD1 PLCB1 AKT2

4.66e-051861546f0c8de4f6ae9047b9108a47a2af8c5f42bc103b0
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Degenerative_Descending_Thin_Limb_Cell_Type_3|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

MYO9A ABCA13 DNAH7 PKHD1 PLCB1 AKT2

4.80e-051871546c31130fc2f9f882944b2ba366a034a03f051c4b9
ToppCellTCGA-Head_and_Esophagus-Primary_Tumor-Head_and_Neck_Carcinoma-Squamous_Cell_Carcinoma-9|TCGA-Head_and_Esophagus / Sample_Type by Project: Shred V9

PPP4R1 RRAS2 DUS2 TUBB6 GSDME PYGL

4.80e-051871546f002ff1a7cb7577f28acff008bc2aa561ac1a4bf
ToppCell5'-Airway_Nasal-Epithelial-Epithelial_transtional-secretory-club_cell-Club_(non-nasal)-Club_(non-nasal)_L.0.4.0.1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

RRAS2 NSF BPIFB1 RILPL1 PLXNB3 PSMG4

4.80e-051871546f5a202d5f8eb57b57d80815ce98774e04c387383
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

MYO9A ABCA13 DNAH7 PKHD1 PLCB1 AKT2

4.94e-051881546af740fa78542438fdff627ea1f74f4eee43316be
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

MYO9A ABCA13 EML6 DNAH7 ALDH1A2 PKHD1

5.09e-051891546904b8337e2cabac2f0bf5dad5598fc429581ed81
ToppCellrenal_medulla_nuclei|World / Celltypes from Cells and Nuclei per compartment and clinical group

MYO9A EML6 ALDH1A2 KIAA1217 PKHD1 PLCB1

5.09e-051891546830d9cd0dd706bce22eb2416f07b2c31c870a05a
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

MYO9A ABCA13 DNAH7 ALDH1A2 PKHD1 PLCB1

5.24e-0519015463fc9e18c7441c0ae8cda65753cc42d0520f4e116
ToppCellPCW_07-8.5-Mesenchymal-Mesenchymal_fibroblastic-mes_immature_COL13A1^pos_fibro1_(4)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

OLFML3 ADAMTS12 CITED2 IL1RAPL1 ALDH1A2 PIEZO2

5.40e-051911546fa380a8752de158974b2ae5e741573439719cc0d
ToppCellCOPD-Stromal-Myofibroblast|Stromal / Disease state, Lineage and Cell class

MAOB ADAMTS12 TGM2 LRRN3 PIEZO2 DST

5.55e-05192154662904f94dfce430456f05066522cbf9bd29f4d7e
ToppCellTCGA-Prostate-Primary_Tumor-Prostate_Adenocarcinoma-Acinar_Adenocarcinoma-6|TCGA-Prostate / Sample_Type by Project: Shred V9

ATRX BCL9 PCNX1 LRRC8B AQR PUS7L

5.72e-051931546abd71b2cf667ef2b1c4d88acd0c1dd19a12ff659
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Thick_Ascending_Limb_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

MYO9A SH2D3A DNAH7 AOPEP PKHD1 PLCB1

5.72e-051931546f42a0f02ed00fe1bb833ff0a0640d9131bca89bd
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

MYO9A SH2D3A DNAH7 AOPEP PKHD1 PLCB1

5.72e-05193154642df7ed37d11fb542b4d1d714b6f87ae8e1396a6
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Intermediate_tubule_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

MYO9A ABCA13 DNAH7 AOPEP PKHD1 PLCB1

5.88e-051941546e577d9e88390b36b5a09b97fe1026089892275a3
ToppCellPBMC_fresh-frozen-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_B-B_cell-B_c02-MS4A1-CD27|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)

PPP4R1 NSF TUBB6 AKT2 PLCG2 GEN1

5.88e-051941546d852aebf7a763b9a776c4570711f0c759f591910
ToppCellPCW_07-8.5-Mesenchymal-Mesenchymal_fibroblastic-mes_immature1_(0)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

OLFML3 ADAMTS12 CITED2 IL1RAPL1 ALDH1A2 PIEZO2

5.88e-051941546a3e5a15cf6c1361207f661ee15eb634f77daf1cb
ToppCell5'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2-Alveolar_fibroblasts-Alveolar_fibroblasts_L.2.1.1.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ABCA10 OLFML3 ADAMTS12 LRRN3 PIEZO2 DST

6.05e-051951546df409f94f4e83be89f7a608058ee07ce3ce3a149
ToppCellCOVID-19-Fibroblasts-Alveolar_FB|COVID-19 / group, cell type (main and fine annotations)

MAOB ABCA10 ADAMTS12 TGM2 PIEZO2 DST

6.05e-051951546603050beeb33c331d4b2e3fa46cae3f3e0e4bdc7
ToppCell5'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2-Alveolar_fibroblasts|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ABCA10 OLFML3 ADAMTS12 LRRN3 PIEZO2 DST

6.05e-0519515464243190ad291d56694e2155954dbaa879c9d3844
ToppCellBronchial-NucSeq-Stromal-Schwann-Schwann_Myelinating|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

SLC16A9 PEX5L IL1RAPL1 PIEZO2 LRRC8B SEC14L5

6.23e-051961546efeb272bc9e37e60d15d056b7574991c5c7501bc
ToppCell5'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ABCA10 OLFML3 ADAMTS12 LRRN3 PIEZO2 DST

6.23e-05196154642e9828222a9663525d571633e8a454c30bfa7f8
ToppCellnucseq-Mesenchymal-Fibroblastic|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

MAOB ABCA10 OLFML3 ADAMTS12 PIEZO2 DST

6.23e-0519615467d8505dac15fa59935ccf592afc54b04c4c6554f
ToppCellLPS_IL1RA-Epithelial_alveolar-AT_1-Differentiating_AT2|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

SH2D3A MYO5C AOPEP CSAD PKHD1 DDX43

6.40e-051971546b94645d57efe8d9e032bffb8c89af1f425c6421e
ToppCell10x_3'_v2v3-Non-neoplastic-Glial-Neuronal-Oligodendrocyte-Oligodendrocyte-B|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

PEX5L FMNL2 TUBB4A PIEZO2 DST SEC14L5

6.40e-05197154682b8e22317cad6d3786bd70d91107007c0ccd7cd
ToppCell3'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2-Alveolar_fibroblasts-Alveolar_fibroblasts_L.2.1.1.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MAOB OLFML3 ADAMTS12 LRRN3 PIEZO2 DST

6.40e-05197154613896ec65ccda0b928c91d41112dc01b480036b7
ToppCellnucseq-Mesenchymal|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

MAOB ABCA10 OLFML3 ADAMTS12 PIEZO2 DST

6.59e-0519815468f52243ca8b9ba68a75ae411506a3a6de258eb97
ToppCellcellseq-Mesenchymal-Fibroblastic-Fibroblastic_2-AF1|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

MAOB OLFML3 ADAMTS12 LRRN3 PIEZO2 DST

6.59e-051981546f1374f7a50244d59c766ac41f44c08c9117407d2
ToppCellproximal-mesenchymal-Alveolar_Fibroblast|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

OLFML3 ADAMTS12 TGM2 LRRN3 PIEZO2 DST

6.77e-0519915467f4840ae6a888380feca722543e5e52783f3e35d
ToppCellproximal-3-mesenchymal-Alveolar_Fibroblast|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

OLFML3 ADAMTS12 TGM2 LRRN3 PIEZO2 DST

6.77e-051991546301d02bbb37e6f1d24b6e865bc3fe3e91260eb30
ToppCellproximal-mesenchymal-Alveolar_Fibroblast-3|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

OLFML3 ADAMTS12 TGM2 LRRN3 PIEZO2 DST

6.77e-0519915469a16e519fb0651a7c4d8e05b931df4fb3b0eb3d1
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Glial-Neuronal-Oligodendrocyte-Oligodendrocyte-G|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

PEX5L FMNL2 TUBB4A PIEZO2 DST SEC14L5

6.77e-051991546214a6a267e77e5508867b9eb48c4fbc7855ed0a0
ToppCellcellseq-Mesenchymal-Fibroblastic-Fibroblastic_2|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

MAOB OLFML3 ADAMTS12 LRRN3 PIEZO2 DST

6.77e-05199154666a79732caf2f04c09b4d9832377aa01ca477677
ToppCell343B-Fibroblasts-Fibroblast-G|343B / Donor, Lineage, Cell class and subclass (all cells)

MAOB OLFML3 ADAMTS12 TGM2 PIEZO2 DST

6.77e-051991546f4b6c095cbe7a38b310adc49be4069e4d56e6a66
ToppCell343B-Fibroblasts-Fibroblast-G-|343B / Donor, Lineage, Cell class and subclass (all cells)

MAOB OLFML3 ADAMTS12 TGM2 PIEZO2 DST

6.77e-0519915469c6d1c328bfbb6547f4c7bb2a784576a56bd72af
ToppCellBronchial-NucSeq-Stromal-Fibroblastic-Fibro_alveolar|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

MAOB ABCA10 ADAMTS12 TGM2 PIEZO2 DST

6.96e-052001546e8462395fee0a532d1e7ec7f1795f28c42af6541
ToppCellParenchyma_Control_(B.)-Stromal-TX-Fibroblasts-1|Parenchyma_Control_(B.) / Sample group, Lineage and Cell type

MAOB OLFML3 ADAMTS12 LRRN3 PIEZO2 DST

6.96e-052001546aa1a35dcca3b799241eef4237f6eb94660e019f0
ToppCellLPS_IL1RA_TNF-Epithelial_alveolar-AT_1-Differentiating_AT1|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

MYO9A SH2D3A ECE1 MYO5C CSAD PKHD1

6.96e-052001546ddfb1f006365bf16203ee49f20200f68220cc288
ToppCellLung_Parenchyma-Control-Mesenchymal-Mesenchymal-Fibroblasts-1|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

MAOB OLFML3 ADAMTS12 LRRN3 PIEZO2 DST

6.96e-052001546a510deaada669e690329183e18df02870bd204b3
ToppCellMS-Multiple_Sclerosis-Lymphocyte-T/NK-ILC|Multiple_Sclerosis / Disease, condition lineage and cell class

GPRASP1 EML6 DUS2 PNMA5 AOPEP MAN1B1

6.96e-052001546ab9bdc9365cbdffe4ed246ce0c8a008a390e387e
ToppCellLPS_IL1RA_TNF-Mesenchymal_fibroblastic-Fibroblasts|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

MAOB ADAMTS12 TGM2 ALDH1A2 DST SRPX

6.96e-05200154644a68bacdb3d5bf563bd35952176995850933a81
ToppCellLPS_IL1RA_TNF-Mesenchymal_fibroblastic|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

MAOB ADAMTS12 TGM2 ALDH1A2 DST SRPX

6.96e-052001546dc61016c61729f69649cfb21f6264e685ce83dea
ToppCellwk_15-18-Mesenchymal-Fibroblast-intermediate_fibro|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

MAOB ABCA10 OLFML3 ADAMTS12 PIEZO2 DST

6.96e-0520015466461d25fd8fb52921b188f083fbe808535d3130b
ToppCellLung_Parenchyma-Control-Mesenchymal-Mesenchymal-Fibroblasts-1-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

MAOB OLFML3 ADAMTS12 LRRN3 PIEZO2 DST

6.96e-052001546dd4228cbed8a4395166a6332e08d44d88bebe3b9
ToppCellHippocampus-Neuronal-Excitatory-eN2(Slc17a7_Slc17a6)-Slc17a6-Excitatory_Neuron.Slc17a6.Grp_(Neuron.Slc17a6.Grp)-|Hippocampus / BrainAtlas - Mouse McCarroll V32

MYH1 MYH2 ESPNL PKHD1

7.60e-05651544b7bc23af54d6d2f7afd584f4df42c24d7c49e344
ToppCellHippocampus-Neuronal-Excitatory-eN2(Slc17a7_Slc17a6)-Slc17a6-Excitatory_Neuron.Slc17a6.Grp_(Neuron.Slc17a6.Grp)|Hippocampus / BrainAtlas - Mouse McCarroll V32

MYH1 MYH2 ESPNL PKHD1

7.60e-056515443b3630253f5713c4a688c74c4ea0f98c1fe42594
ToppCellFrontal_cortex-Neuronal-Excitatory-eN1(Slc17a7)-eN1_2-Nptxr-Excitatory_Neuron.Slc17a7.Nptxr-Calb1_(Superficial_layer_pyramidal_cells--Layer_2/3)|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

ESPNL RILPL1 BCO1 PNMA5 PKHD1

7.70e-0512615457dcc79bf35482e8e5e5a1de7279ba080edb70522
ToppCell3'_v3-blood-Lymphocytic_T_CD4-T_CD4/CD8|blood / Manually curated celltypes from each tissue

CASP8 BTAF1 PKHD1 PCNX1 PLCG2

1.07e-041351545ae2d3a42e567b5bade304c0caa497eb725be3565
ToppCell(01)_Cycling_Basal_(homeostasis)-(1)_24hpi|(01)_Cycling_Basal_(homeostasis) / shred by cell type and Timepoint

MAOB EML6 ESPNL PKHD1

1.07e-047115446aa56b0daaeb5e0ae30619f9c6945c8e42899b27
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_2|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

MYH1 MYH4 ABCA13 AGPS PKHD1

1.10e-04136154582b1d6d839c0d0c68e0960549f688138479defcc
ToppCellPCW_05-06-Epithelial-Epithelial_ciliated-epi_ciliated_(14)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

CFAP47 PAK6 LRRC9 PKHD1 TRPV6

1.27e-0414015458abbd5dc799943b49cd0045d0da405c3f3d0db6b
ToppCellPCW_05-06-Epithelial-Epithelial_ciliated|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

CFAP47 PAK6 LRRC9 PKHD1 TRPV6

1.27e-041401545e4689232c473d239b07a7fbcaaa3414fbd9badea
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_3|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

MYO9A ABCA13 ALDH1A2 PKHD1 AKT2

1.40e-0414315457a7a9829ba63468c9745904d9e993590051207ab
ToppCellThalamus-Neuronal-Excitatory-eN2(Slc17a7_Slc17a6)-Slc17a7-Tac2-Excitatory_Neuron.Slc17a7.Tac2.Syt15_(Medial_habenula)|Thalamus / BrainAtlas - Mouse McCarroll V32

MYH1 MYH2 MYH4 CATSPERG

1.47e-047715447f624e9262bd0dc2ac4176f43c91a4bc0f521fe5
ToppCellfacs-Marrow-T_cells-18m-Lymphocytic-lymphoid_progenitor_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EML6 LRRC9 ADAMTS12 TUBB4A NEURL4

1.86e-041521545acfafdb64bd5b0eb7371b04cfef51ed2798e9b30
ToppCellfacs-Marrow-T_cells-18m-Lymphocytic-common_lymphoid_progenitor_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EML6 LRRC9 ADAMTS12 TUBB4A NEURL4

1.86e-0415215459d6c88ceca0569dbeb12e488acec7fcb7f972f03
Drugeye gene

MYH1 MYH2 MYH4 MAOB MYO9A TRPC1 MYO5C BCO1 ACTL8 PLCB1 PYGL AKT1 PLCG2

1.34e-0636915313CID000004782
DrugAC1L1IZ2

MYH1 MYH2 MYH4 TRPM7 MYO9A AGPS MYO5C TUBB6 TUBB4A ACTL8 AKT2

6.98e-0630415311CID000004795
DrugRicinine [524-40-3]; Down 200; 24.4uM; MCF7; HT_HG-U133A

CASP8 ECE1 C2orf68 SCAF4 ACTL8 PLCB1 TRPV6 AKT2 ZMYM6

7.11e-0619515396067_DN
DrugNSC339663

MYH1 MYH2 MYH4 MYO9A MYO5C PIKFYVE TUBB6 TUBB4A ACTL8 AKT1

7.73e-0625015310CID000003892
DrugCHEMBL459685

CASP8 PIKFYVE AKT1 AKT2 PLCG2

8.93e-06421535CID010995375
Drug4-chloroaniline

MYH1 MYH2 MYH4 COX11 PAK6 ACTL8 PNMA2 TRPV6 AKT1

9.44e-062021539CID000007812
Drugblebbistatin

MYH1 MYH2 MYH4 MYO9A MYO5C ACTL8 AKT1

1.36e-051161537CID003476986
DrugB0683

MYH1 MYH2 MYH4 MYO9A MYO5C ACTL8 GLUD1

1.44e-051171537CID006398969
DrugET-18-OCH3

TRPM7 AGPS GSDME PLCB1 TRPV6 AKT1 PLCG2

1.70e-051201537CID000001392
DrugArbutin

ABCA13 CASP8 ECE1 DNAH7 ABCA10 KCTD17 FMNL3 SF3B1 PKHD1 AKT1

2.26e-0528315310ctd:D001104
Drugformycin triphosphate

MYH1 MYH2 MYH4 MYO9A MYO5C

2.35e-05511535CID000122274
DrugAC1LADJ6

MYH1 MYH2 MYH4 ETV4 DUS2 ACTL8 GLUD1

2.86e-051301537CID000486032
DiseaseNeoplasm of uncertain or unknown behavior of ovary

RRAS2 MSH6 AKT1 AKT2

1.31e-05291484C0496920
DiseaseHematopoetic Myelodysplasia

SAMD9 ATRX SF3B1 PLCB1

1.31e-05291484C2713368
Diseaseautosomal dominant hyaline body myopathy (implicated_via_orthology)

MYH1 MYH2 MYH4

1.45e-05101483DOID:0111269 (implicated_via_orthology)
Diseasedistal arthrogryposis type 2B3 (implicated_via_orthology)

MYH1 MYH2 MYH4

1.45e-05101483DOID:0111602 (implicated_via_orthology)
Diseasedistal arthrogryposis type 1 (implicated_via_orthology)

MYH1 MYH2 MYH4

1.45e-05101483DOID:0111596 (implicated_via_orthology)
Diseasedilated cardiomyopathy 1S (implicated_via_orthology)

MYH1 MYH2 MYH4

1.45e-05101483DOID:0110454 (implicated_via_orthology)
Diseasecongenital myopathy 6 (implicated_via_orthology)

MYH1 MYH2 MYH4

1.45e-05101483DOID:0080719 (implicated_via_orthology)
Diseaseinclusion body myositis (implicated_via_orthology)

MYH1 MYH2 MYH4

1.45e-05101483DOID:3429 (implicated_via_orthology)
Diseasedistal arthrogryposis type 2A (implicated_via_orthology)

MYH1 MYH2 MYH4

1.45e-05101483DOID:0111605 (implicated_via_orthology)
Diseasefamilial hypertrophic cardiomyopathy (implicated_via_orthology)

MYH1 MYH2 MYH4

1.45e-05101483DOID:0080326 (implicated_via_orthology)
DiseaseOvarian Carcinoma

RRAS2 MSH6 AKT1 AKT2

1.50e-05301484C0029925
Diseasedistal myopathy (implicated_via_orthology)

MYH1 MYH2 MYH4

2.63e-05121483DOID:11720 (implicated_via_orthology)
Diseasemyotonia congenita (implicated_via_orthology)

MYH1 MYH2 MYH4

2.63e-05121483DOID:2106 (implicated_via_orthology)
Diseaserestrictive cardiomyopathy (implicated_via_orthology)

MYH1 MYH2 MYH4

3.41e-05131483DOID:397 (implicated_via_orthology)
Diseasedistal arthrogryposis (implicated_via_orthology)

MYH1 MYH2 MYH4

5.38e-05151483DOID:0050646 (implicated_via_orthology)
DiseaseColorectal Carcinoma

AKAP6 TRPM7 ABCA13 APC CASP8 PAK6 PEX5L ABCA10 TGM2 MSH6 SACS PKHD1 AKT1

5.65e-0570214813C0009402
DiseaseAdenocarcinoma of large intestine

APC MSH6 TBK1 AKT1 AKT2

1.26e-04961485C1319315
Diseasemalignant astrocytoma (is_marker_for)

ATRX AKT1 AKT2

2.03e-04231483DOID:3069 (is_marker_for)
Diseaseadverse effect, response to xenobiotic stimulus

CENPC SCAF4 FMNL3 PLCB1

2.23e-04591484EFO_0009658, GO_0009410
Diseaselactic acidosis (implicated_via_orthology)

PYGL TRMT5

2.47e-0451482DOID:3650 (implicated_via_orthology)
DiseaseTurcot syndrome (disorder)

APC MSH6

2.47e-0451482C0265325
Diseasesuicide ideation measurement

AOPEP PLCB1

2.47e-0451482EFO_0007619
DiseaseMalignant neoplasm of breast

AKAP6 MYH1 SH2D3A ARFGEF2 ETV4 CASP8 TGM2 MSH6 MTR PLCB1 UTP20 AKT1 AKT2 LONRF3 GEN1

3.41e-04107414815C0006142
DiseaseMYELODYSPLASTIC SYNDROME

SAMD9 ATRX SF3B1 PLCB1

3.64e-04671484C3463824
Diseaseheart septal defect

WDR7 YTHDC2

3.70e-0461482MONDO_0002078
DiseaseMalignant Neoplasms

APC CITED2 SF3B1 AKT1 AKT2

4.78e-041281485C0006826
Diseaseovarian neoplasm

RRAS2 BCL9 MSH6 AKT1 AKT2

5.89e-041341485C0919267
DiseaseMalignant neoplasm of ovary

RRAS2 BCL9 MSH6 AKT1 AKT2

6.52e-041371485C1140680
Diseasehypoglycemia (is_implicated_in)

GLUD1 AKT2

6.86e-0481482DOID:9993 (is_implicated_in)
Diseaseovarian cancer (implicated_via_orthology)

APC MSH6

6.86e-0481482DOID:2394 (implicated_via_orthology)
DiseaseBipolar Disorder

MAOB ABCA13 CASP8 BCL9 TGM2 MTR PLCB1 AKT1 AKT2

7.07e-044771489C0005586
Diseaseendometrial cancer (is_implicated_in)

APC MSH6 AKT2

7.82e-04361483DOID:1380 (is_implicated_in)
Diseaseosteoarthritis, hand

MYH2 SUPT3H ALDH1A2

8.48e-04371483EFO_1000789
DiseaseHEPATOCELLULAR CARCINOMA

APC CASP8

8.79e-0491482114550
DiseaseLynch Syndrome

APC MSH6

8.79e-0491482C4552100
DiseaseHepatocellular carcinoma

APC CASP8

8.79e-0491482cv:C2239176
Diseasecholesterol in very small VLDL measurement

ABCA10 ALDH1A2 PCIF1

1.07e-03401483EFO_0022231
Diseaseptosis (implicated_via_orthology)

TUBB6 TUBB4A

1.10e-03101482DOID:0060260 (implicated_via_orthology)
Diseasetubulinopathy (implicated_via_orthology)

TUBB6 TUBB4A

1.10e-03101482DOID:0112227 (implicated_via_orthology)
Diseasefacial paralysis (implicated_via_orthology)

TUBB6 TUBB4A

1.10e-03101482DOID:13934 (implicated_via_orthology)
Diseasecomplex cortical dysplasia with other brain malformations 7 (implicated_via_orthology)

TUBB6 TUBB4A

1.10e-03101482DOID:0090132 (implicated_via_orthology)
DiseaseNeoplasm of uncertain or unknown behavior of breast

CASP8 AKT1 AKT2

1.15e-03411483C0496956
DiseaseBreast adenocarcinoma

CASP8 AKT1 AKT2

1.15e-03411483C0858252
Diseaseoral microbiome measurement

NRDC APPL2 KIAA1217

1.23e-03421483EFO_0801229
Diseasepolybrominated biphenyl measurement, gestational serum measurement, fetal genotype effect measurement, polybrominated diphenyl ether measurement

PEX5L LOXHD1

1.33e-03111482EFO_0007959, EFO_0007961, EFO_0007962, EFO_0007964
Diseasecerebellar ataxia, mental retardation and dysequlibrium syndrome (implicated_via_orthology)

TUBB6 TUBB4A

1.60e-03121482DOID:0050997 (implicated_via_orthology)
Diseasemismatch repair cancer syndrome (is_implicated_in)

MSH6 RNASET2

1.60e-03121482DOID:0112182 (is_implicated_in)
DiseasePancreatic Neoplasm

ATRX APC TGM2 AKT2

1.64e-031001484C0030297
Diseasefree cholesterol in very small VLDL measurement

ABCA10 ALDH1A2 PCIF1

1.71e-03471483EFO_0022275
DiseaseMalignant neoplasm of pancreas

ATRX APC TGM2 AKT2

1.76e-031021484C0346647
Diseasemyopathy (implicated_via_orthology)

MYH1 MYH2 MYH4

1.81e-03481483DOID:423 (implicated_via_orthology)
DiseaseBenign tumor of pancreas

APC AKT2

1.88e-03131482C0347284
DiseaseIntellectual Disability

AKAP6 NSF APC SACS RNASET2 MED12L ZMYM6 MAN1B1

1.94e-034471488C3714756
Diseasetype 2 diabetes mellitus (implicated_via_orthology)

IDE MTR AKT1 AKT2

1.96e-031051484DOID:9352 (implicated_via_orthology)
Diseaselysophosphatidylcholine 15:0 measurement

ALDH1A2 PKHD1

2.19e-03141482EFO_0020941
Diseasephospholipids in IDL measurement

ABCA10 ALDH1A2 PCIF1

2.28e-03521483EFO_0022164
Diseasecholesterol in small VLDL measurement

ABCA10 ALDH1A2 PCIF1

2.41e-03531483EFO_0022228
Diseasepancreatic cancer (is_implicated_in)

APC CASP8 MTR AKT1

2.48e-031121484DOID:1793 (is_implicated_in)
DiseaseMuscular Atrophy

CITED2 AKT1

2.51e-03151482C0026846
DiseaseReplication Error Phenotype

MSH6 XPO5

2.51e-03151482C1721098
DiseaseMicrosatellite Instability

MSH6 XPO5

2.51e-03151482C0920269
DiseaseYu-Zhi constitution type

FREM2 PIEZO2

2.51e-03151482EFO_0007638
Diseasetriglycerides to total lipids in chylomicrons and extremely large VLDL percentage

ALDH1A2 PCIF1

2.51e-03151482EFO_0022328
DiseaseNeurogenic Muscular Atrophy

CITED2 AKT1

2.51e-03151482C0270948
Diseasehepcidin:transferrin saturation ratio

EML6 KCTD17

2.51e-03151482EFO_0007902
DiseaseColorectal Neoplasms

TRPM7 ABCA13 APC CASP8 ABCA10 AKT1

2.81e-032771486C0009404
Diseasetriglycerides in very large VLDL measurement

EXOC6 ALDH1A2 PCIF1

2.82e-03561483EFO_0022325
Diseaseautosomal recessive polycystic kidney disease (implicated_via_orthology)

PKHD1 AKT1

2.86e-03161482DOID:0110861 (implicated_via_orthology)
DiseasePolyposis, Adenomatous Intestinal

APC AKT1

2.86e-03161482C2713442
DiseaseFamilial Intestinal Polyposis

APC AKT1

2.86e-03161482C2713443
Diseaseexecutive function measurement

NSF ARFGEF2 PAK6 ERLIN1 MYO5C PIEZO2 XPO5

2.97e-033761487EFO_0009332
Diseaselow density lipoprotein particle size measurement

SLC16A9 ALDH1A2 PCIF1

3.12e-03581483EFO_0008593
Diseasegout

TRIM46 SLC16A9 ALDH1A2 DST GLUD1

3.16e-031961485EFO_0004274
Diseasecortical surface area measurement

RABEP2 EXOC6 RRAS2 SUPT3H SAMD9 NSF APC ARHGAP39 FMNL2 DNAH7 ALDH1A2 SF3B1 AOPEP XRN1 PKHD1

3.19e-03134514815EFO_0010736
DiseaseAdenomatous Polyposis Coli

APC AKT1

3.23e-03171482C0032580
Diseasecholesterol to total lipids in chylomicrons and extremely large VLDL percentage

ALDH1A2 PCIF1

3.23e-03171482EFO_0022232
DiseaseProstatic Neoplasms

CDK2AP2 SAMD9 APC ETV4 PAK6 ALDH1A2 SF3B1 APPL2 AKT1

4.01e-036161489C0033578
DiseaseMalignant neoplasm of prostate

CDK2AP2 SAMD9 APC ETV4 PAK6 ALDH1A2 SF3B1 APPL2 AKT1

4.01e-036161489C0376358
DiseasePancreatic carcinoma

APC AKT2

4.04e-03191482C0235974
Diseaseesterified cholesterol measurement, high density lipoprotein cholesterol measurement

ALDH1A2 PCIF1

4.04e-03191482EFO_0004612, EFO_0008589
Diseasesusceptibility to hepatitis B infection measurement

EML6 ARFGEF2 YTHDC2

4.12e-03641483EFO_0008405
Diseaseprostate adenocarcinoma (is_implicated_in)

AKT1 AKT2

4.47e-03201482DOID:2526 (is_implicated_in)
DiseaseFetal Growth Retardation

SAMD9 GLUD1

4.47e-03201482C0015934
Diseaseobesity (implicated_via_orthology)

ETV4 ALDH1A2 MED12L PLCB1 PLXNB3

4.67e-032151485DOID:9970 (implicated_via_orthology)
Diseasetotal lipids in large VLDL

EXOC6 ALDH1A2 PCIF1

4.68e-03671483EFO_0022175
Diseaseschizophrenia (implicated_via_orthology)

LRRN3 PLCB1 AKT1

4.88e-03681483DOID:5419 (implicated_via_orthology)
DiseaseBREAST CANCER

CASP8 AKT1

4.93e-03211482114480
Diseasefree cholesterol to total lipids in chylomicrons and extremely large VLDL percentage

ALDH1A2 PCIF1

4.93e-03211482EFO_0022277
Diseasecholesteryl esters to total lipids in chylomicrons and extremely large VLDL percentage

ALDH1A2 PCIF1

4.93e-03211482EFO_0022246

Protein segments in the cluster

PeptideGeneStartEntry
MKIRERNKPEIFELI

UNC13A

631

Q9UPW8
KLFELILMEEIRFPR

AKT1

356

P31749
ERLFELILMEEIRFP

AKT2

356

P31751
EFIPEARGLEFLMIL

CATSPERG

451

Q6ZRH7
IEFPILKLNGRTMEI

ERI3

166

O43414
DILEEIIRQMKVFHP

NT5C3B

161

Q969T7
QELLVKIPLDMVAGF

BPIFB1

106

Q8TDL5
PKEVEQEVKRIIMEL

ABCA10

501

Q8WWZ4
REPADRKKMLEILFE

ACTL8

106

Q9H568
MRIAKEEIFGPVQEI

ALDH1A2

411

O94788
KIPEAIRRNFELMEA

ERLIN1

176

O75477
AVLFDDELLMVLEPV

GSDME

316

O60443
EIMQFDLIPELRAVL

ARFGEF2

1741

Q9Y6D5
PEIRKEVFELLEMGV

CMSS1

251

Q9BQ75
NMFINLPRVKELLED

ABCA13

3261

Q86UQ4
ERFIELMIDLEALLP

AQR

251

O60306
FLQMLLENIPEEKRL

AOPEP

626

Q8N6M6
PMREALKLRIQEEIA

C2orf68

146

Q2NKX9
FDVMFKLEVPRIQLE

CGAS

226

Q8N884
LEMPLSIFVEAEEKR

CCER1

361

Q8TC90
LIPKGARDIRVMEIE

ADAMTS12

721

P58397
GMEFKLIEPEEVARL

ETV4

366

P43268
KLREIVLPMEKEIEE

RABEP2

151

Q9H5N1
ERMLIKVADREPSFL

ARHGAP39

211

Q9C0H5
LMEELVNFIERVPKA

INTS9

136

Q9NV88
KMLPLLEVAEKEREA

OLFML3

61

Q9NRN5
DLKFDDEVIKMEPRI

LRRC9

656

Q6ZRR7
LLLIAEVMGEDIPEK

C8orf76

311

Q96K31
IMDLLGDRVKLERPV

MAOB

221

P27338
VKEEEFIMPLISIIG

SLC16A9

336

Q7RTY1
PDLASLRKERIIMLF

ESPNL

731

Q6ZVH7
KVSPVLRDFLERMLV

PAK6

626

Q9NQU5
LDVLEKIRPMDDDLL

MED12L

256

Q86YW9
KLEAVDLMEPRLICV

L3MBTL2

541

Q969R5
LVPEFRGVMKVDINL

GPR158

296

Q5T848
IIAMLEREKALRPEV

DST

366

Q03001
ALEGIEKFELVLRMP

FREM2

2091

Q5SZK8
EILDIAPFTKMRIRI

LOXHD1

1606

Q8IVV2
DLERPLELRVKVMDI

DSG4

136

Q86SJ6
ISFLFLEPMEEKLVV

FETUB

341

Q9UGM5
FGREIVEMLLEKLQL

FSIP2

2916

Q5CZC0
MEIRLPDLALKRIFS

FBXW12

1

Q6X9E4
FADMELLRKVVVPGI

PCNX1

1841

Q96RV3
LLREDVEFQPLTLMV

PLXNB3

1506

Q9ULL4
LRLIYNIVEEEPLML

FAT2

2201

Q9NYQ8
EERFALEILPDMLEK

IL1RAPL1

426

Q9NZN1
LIEKPMGIFSILEEE

MYH2

526

Q9UKX2
GLPTEERIQKLEFML

PDZD8

1026

Q8NEN9
RLKEGDLPVTILFME

PEX5L

336

Q8IYB4
EALLRPGRLEVKMEI

NSF

381

P46459
LIEKPMGIFSILEEE

MYH1

526

P12882
PPSFLELMKVIREEE

PNMA2

321

Q9UL42
IEGFLDIMEIKEIRP

PLCG2

61

P16885
RLDAIEDLMVVPDKI

MSH6

791

P52701
NIGPLIRIIKDRMEE

KCTD17

116

Q8N5Z5
MIENLPKLREDIKEI

EXOC6

181

Q8TAG9
EMEVLSLELIPEVKL

LRRC8B

441

Q6P9F7
LAFRLEEEQKMRPEI

MAN1B1

111

Q9UKM7
PVFLEKEMLLEIPEN

PCDHB12

131

Q9Y5F1
DDRFILKQMPRLEVQ

PIKFYVE

1871

Q9Y2I7
DPENRIAKKMLLEEI

ATRX

1266

P46100
DLLSVIEEMGKEIRP

CDK2AP2

76

O75956
EIMNDIPIRLSRIKF

PCIF1

266

Q9H4Z3
VLPFLLRRMKEDVLQ

BTAF1

1496

O14981
MKKELNPVELDFLLR

DNAH17

3741

Q9UFH2
RVKDPETREIILMDL

CENPC

826

Q03188
PEADKIFLERNIMVI

GLUD1

411

P00367
PEFAEDPRMIKVDLI

COX11

241

Q9Y6N1
EILEFPELKGIIFMQ

DIS3L

71

Q8TF46
LMRFLPTEAEVKLLR

FMNL3

681

Q8IVF7
LRDIQRMLFPDEKEF

BCL9

366

O00512
DKVIPMLQEFIINRL

DNAH7

3391

Q8WXX0
MVLPIIQFREKDLTE

APPL2

111

Q8NEU8
EPIKDALMLFQRLQE

CASP8

36

Q14790
APVFVLMEEEVLRKL

CSAD

121

Q9Y600
LMRFLPTENEVKVLR

FMNL2

736

Q96PY5
PDLLLFQRFTLEKME

GEN1

351

Q17RS7
LEEFRPDLIEMVLDK

IDE

456

P14735
FEVIVRERDKPMLIL

EML6

306

Q6ZMW3
IEELRAKPLMELIER

ECE1

191

P42892
IFLKEGLRPLEEVMQ

DUS2

251

Q9NX74
PVEEGDRKISLIMEL

CCDC192

211

P0DO97
GVFKIEIIQPLLDMA

SCAF4

121

O95104
PGVKALLRMIEVVED

SEC14L5

396

O43304
QEIEAELRDPLMIFV

SACS

2066

Q9NZJ4
ELRDPLMIFVLNEKV

SACS

2071

Q9NZJ4
RDMQLRVIPAEVKFL

CFAP47

36

Q6ZTR5
FEPQIMKILLDVRPD

DDX43

406

Q9NXZ2
PLRDNEMFEIRIDKL

NEURL4

356

Q96JN8
TKRLLLPLFREVDMV

NTMT1

76

Q9BV86
FEELLLLMEKIRDPF

GPRASP1

1156

Q5JY77
FQLIEEVPMIKDISL

RTP3

131

Q9BQQ7
EEVVRVPLAFAMVKL

UTP20

1816

O75691
REMKLLTELNFLRVP

TRIM46

416

Q7Z4K8
VIEDPEDKESRLIML

TRMT5

126

Q32P41
MEEDLFQLRQLPVVK

SVOP

1

Q8N4V2
MFPTLEIDIEGQLKR

ADSS1

206

Q8N142
KDITERLILPRFCEM

PPP4R1

206

Q8TF05
EILMIGENPIIRIKD

LRRN3

191

Q9H3W5
MPEFKVRERALLEAL

PUS7L

491

Q9H0K6
EDIMPRGKFLVVFLL

SAMD9

531

Q5K651
ELEDFIMLLEAALPR

HS2ST1

256

Q7LGA3
IFVAKEMERLAIRIP

MTR

841

Q99707
ILRVKDRDEFPMILI

RRAS2

111

P62070
KPVIIIFDEPMDIRS

KIAA1217

1441

Q5T5P2
LIEKPMGIFSILEEE

MYH4

526

Q9Y623
EDLFLNVKPRLDMVE

PKHD1

1011

P08F94
LLVENRIKEEMEAFP

PSMG4

106

Q5JS54
LIDTFPLRKEEMVLQ

SRPX

441

P78539
MEKEFPELIRSVGLL

AKAP6

261

Q13023
LLPGLEERLMKEVEQ

ACTRT1

306

Q8TDG2
VIFLEQPFRLDILKM

BCO1

246

Q9HAY6
LLREGMFERIPDIVL

AGPS

196

O00116
LDEPFIQKDVELRIM

APC

1511

P25054
LVIEMGLDRIKELPE

CITED2

231

Q99967
AEPLQLLLAKVMRFE

CNBD2

121

Q96M20
PNFLELMKLIRDEEE

PNMA5

316

Q96PV4
PVEAGEEVKVRMDLL

TGM2

641

P21980
IMLTEEDPILRAFEL

TRPC1

226

P48995
FNLEEIKDLLPEMRA

RNASET2

81

O00584
VDVRVDGLMLKFVIP

UHRF1BP1L

571

A0JNW5
LEEKNRMLQEDPVLF

GTF2H1

111

P32780
LVPIQRDLYKEVMLE

ZNF2

31

Q9BSG1
RVITPEDLLFLMRKD

SUPT3H

76

O75486
ARLMPKVVRVLEILE

RILPL1

51

Q5EBL4
LISKIREEFPDRIMN

TUBB6

151

Q9BUF5
EAALAFEQELKPLMR

SH2D3A

441

Q9BRG2
LILIREFQSPDEEMK

SF3B1

771

O75533
LISKIREEFPDRIMN

TUBB4A

151

P04350
IMFEELPNVDRILKL

PIEZO2

2696

Q9H5I5
LPLLLVDEMEEKDIL

USP25

966

Q9UHP3
IPFIDEKRLLEAMET

XRN1

566

Q8IZH2
LEDRKPLMVLFGDVA

XPO5

281

Q9HAV4
AIIILLVEVPDIFRM

TRPV6

436

Q9H1D0
MLQKLGPEKRIFEEI

NRDC

531

O43847
RILEKLKPLMDVDEE

PSME4

1536

Q14997
RLPLEILEFVQEAMK

PLCB1

1156

Q9NQ66
VRLVKLPFFNMLDEL

PIAS4

131

Q8N2W9
VIPARLLKMEVRAEE

nan

36

A8MV72
RPFEVKEMFLEDILR

YTHDC2

371

Q9H6S0
RDVKEELLFCIEMPT

ZMYM6

936

O95789
LPNFLELIKMIREEE

ZCCHC18

206

P0CG32
IMFEELPCVDRILKL

PIEZO1

2466

Q92508
KLMEPERLNEIVEKF

ZMYM1

1121

Q5SVZ6
ILLEAIERFIEPHEM

SLC30A1

96

Q9Y6M5
LILDFVLKQDMPLVG

TIGD7

51

Q6NT04
AIPELMRIFVDIEKL

PYGL

346

P06737
EILIEKMPTDVVDLL

WDR7

1311

Q9Y4E6
ITEEIPMEVFKEVRI

TRPM7

806

Q96QT4
LRPVDVQMREFEVLK

TBK1

46

Q9UHD2
LPNFLELIRMVREEE

ZCCHC12

206

Q6PEW1
RPEMRTKEQILELLV

ZNF263

71

O14978
GVEQLMFIKEDLILP

FAM50B

231

Q9Y247
VIMEELIAKFLPEEL

LONRF3

521

Q496Y0
IEEFMSQPEKLLFII

NLRP13

296

Q86W25
QPVIDLIEAKMGILE

MYO5C

491

Q9NQX4
EKEELTFEMLVLEPR

MYO9A

2346

B2RTY4