Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	actin filament binding	MYO7A MYO9A MYO10 SPTA1 SPTB GAS2 ITPRID2 FGD4 AVIL MACF1 TRPV4	1.36e-05	227	193	11	GO:0051015
GeneOntologyMolecularFunction	cytoskeletal protein binding	VAPB HAUS6 MYO7A MYO9A MYO10 SPTA1 SPTB GAS2 LRRK2 GAS8 OBSCN CLSTN2 ITPRID2 TUBGCP2 PTK2 PTPRC BMP10 FGD4 SYNE2 UTRN KIF16B AVIL MACF1 TRPV4 MX1 KIF1C	2.21e-05	1099	193	26	GO:0008092
GeneOntologyMolecularFunction	actin binding	MYO7A MYO9A MYO10 SPTA1 SPTB GAS2 LRRK2 ITPRID2 PTK2 FGD4 SYNE2 UTRN AVIL MACF1 TRPV4	6.84e-05	479	193	15	GO:0003779
GeneOntologyMolecularFunction	phosphatidylinositol-3,4,5-trisphosphate binding	MYO10 OBSCN AKT1 PLEKHB2 KIF16B	1.08e-04	49	193	5	GO:0005547
GeneOntologyMolecularFunction	protein serine/threonine kinase activity	HIPK1 RPS6KA3 LRRK2 OBSCN MELK PIK3R4 PHKG2 RPS6KA6 AKT1 ULK1 HIPK4 PDPK2P BRD2 PRKDC	1.17e-04	446	193	14	GO:0004674
GeneOntologyMolecularFunction	cytoskeletal motor activity	MYO7A MYO9A MYO10 DNAH10 KIF16B DNAH1 KIF1C	1.51e-04	118	193	7	GO:0003774
GeneOntologyMolecularFunction	microtubule binding	VAPB HAUS6 GAS2 LRRK2 GAS8 TUBGCP2 KIF16B MACF1 TRPV4 MX1 KIF1C	2.13e-04	308	193	11	GO:0008017
GeneOntologyMolecularFunction	kinase activity	HIPK1 RPS6KA3 LRRK2 OBSCN GCK MELK PTK2 PIK3R4 PHKG2 RPS6KA6 ALDH18A1 AKT1 ULK1 HIPK4 PDPK2P BRD2 PRKDC PALS2	4.59e-04	764	193	18	GO:0016301
GeneOntologyMolecularFunction	protein kinase activity	HIPK1 RPS6KA3 LRRK2 OBSCN MELK PTK2 PIK3R4 PHKG2 RPS6KA6 AKT1 ULK1 HIPK4 PDPK2P BRD2 PRKDC	7.58e-04	600	193	15	GO:0004672
GeneOntologyMolecularFunction	protein serine kinase activity	HIPK1 RPS6KA3 LRRK2 OBSCN MELK PIK3R4 RPS6KA6 AKT1 ULK1 HIPK4 PRKDC	8.43e-04	363	193	11	GO:0106310
GeneOntologyCellularComponent	cell cortex	MYO7A MYO10 ERC1 SPTA1 SPTB GCK MELK PTK2 AKT1 GRB2 PDE4DIP MACF1 TRPV4 RIMS2	1.08e-05	371	195	14	GO:0005938
GeneOntologyCellularComponent	filopodium	MYO10 FGD4 SYNE2 UTRN VCAM1 NPTXR TRPV4	1.57e-04	123	195	7	GO:0030175
GeneOntologyCellularComponent	supramolecular fiber	HAUS6 MYO9A GAS2 GAS8 OBSCN GCK DBI TUBGCP2 CMYA5 KAT2B BMP10 SYNE2 DNAH10 KIF16B DNAH1 AVIL PDE4DIP CCT8 MACF1 TRPV4 TUBE1 MX1 AHNAK2 KIF1C	2.72e-04	1179	195	24	GO:0099512
GeneOntologyCellularComponent	supramolecular polymer	HAUS6 MYO9A GAS2 GAS8 OBSCN GCK DBI TUBGCP2 CMYA5 KAT2B BMP10 SYNE2 DNAH10 KIF16B DNAH1 AVIL PDE4DIP CCT8 MACF1 TRPV4 TUBE1 MX1 AHNAK2 KIF1C	3.00e-04	1187	195	24	GO:0099081
GeneOntologyCellularComponent	lamellipodium	MYO10 PTK2 FGD4 SYNE2 AKT1 ARHGEF6 AVIL CSPG4 TRPV4	3.21e-04	230	195	9	GO:0030027
Domain	Spectrin	SPTA1 SPTB SYNE2 UTRN MACF1	3.24e-06	23	193	5	PF00435
Domain	CH	SPEF2 SPTB GAS2 SYNE2 UTRN ARHGEF6 MACF1	1.03e-05	73	193	7	PS50021
Domain	Spectrin_repeat	SPTA1 SPTB SYNE2 UTRN MACF1	1.09e-05	29	193	5	IPR002017
Domain	CH-domain	SPEF2 SPTB GAS2 SYNE2 UTRN ARHGEF6 MACF1	1.24e-05	75	193	7	IPR001715
Domain	SPEC	SPTA1 SPTB SYNE2 UTRN MACF1	1.80e-05	32	193	5	SM00150
Domain	Spectrin/alpha-actinin	SPTA1 SPTB SYNE2 UTRN MACF1	1.80e-05	32	193	5	IPR018159
Domain	CH	SPTB GAS2 SYNE2 UTRN ARHGEF6 MACF1	5.61e-05	65	193	6	SM00033
Domain	ACTININ_2	SPTB SYNE2 UTRN MACF1	8.39e-05	23	193	4	PS00020
Domain	ACTININ_1	SPTB SYNE2 UTRN MACF1	8.39e-05	23	193	4	PS00019
Domain	Actinin_actin-bd_CS	SPTB SYNE2 UTRN MACF1	8.39e-05	23	193	4	IPR001589
Domain	CH	SPTB GAS2 SYNE2 UTRN ARHGEF6 MACF1	8.53e-05	70	193	6	PF00307
Domain	-	SPTB GAS2 SYNE2 UTRN ARHGEF6 MACF1	9.24e-05	71	193	6	1.10.418.10
Pubmed	N-Terminomics for the Identification of In Vitro Substrates and Cleavage Site Specificity of the SARS-CoV-2 Main Protease.	RABEP2 ERG ERC1 SPTB EHD2 SAFB ALDH18A1 UTRN HSPA4 SF3B2 PPFIBP1 MACF1 PRKDC LRRFIP1 AHNAK2	3.04e-09	360	199	15	33111431
Pubmed	A Degradation Motif in STAU1 Defines a Novel Family of Proteins Involved in Inflammation.	ZNF346 HAUS6 MYCBP2 ERC1 HNRNPA1 PTK2 WIZ ASCC2 DNAJC13 LIMD1 PATL1 PPP1R10 IBTK RRN3 UTP4 CCT8 UNK MACF1 LRRFIP1 AHNAK2	8.07e-09	724	199	20	36232890
Pubmed	Tagging genes with cassette-exchange sites.	VAPB BNC2 ZNF346 UGGT1 TM7SF3 PTK2 DMXL1 ZNF462 SAFB PLXNA1 CHD8 RNF220 DNAJC11 MACF1	9.99e-09	335	199	14	15741177
Pubmed	N-Terminal Acetyltransferase Naa40p Whereabouts Put into N-Terminal Proteoform Perspective.	VAPB STAM2 HAUS6 ERC1 TIPRL HNRNPA1 SAFB WIZ UTRN HSPA4 SF3B2 LIMD1 POLDIP3 SMCHD1 THOC2 PPP1R10 IBTK UTP4 CCT8 MACF1 PRKDC AHNAK2	2.43e-08	934	199	22	33916271
Pubmed	Transcriptome characterization elucidates signaling networks that control human ES cell growth and differentiation.	CPNE2 MYCBP2 SPTB PKD1L1 KIAA0586 LRRK2 OBSCN ETV1 GON4L COPS2 DMXL1 TASOR2 BNC1 SAFB TRANK1 GCLM AKT1 ADAM17 UTRN CHD8 TRIM33 RNF220 BRD2 PWWP3B RIMS2	3.56e-08	1215	199	25	15146197
Pubmed	Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.	KDM3A ERG MYCBP2 ERC1 HIPK1 SPTB CMYA5 PTK2 PIK3R4 GDAP1L1 WIZ USP32 UTRN SF3B2 PLEKHB2 RAP1GDS1 PPFIBP1 TRIM33 RNF220 BRD2 PDE4DIP MACF1 PRKDC PALS2 LRRFIP1	1.04e-07	1285	199	25	35914814
Pubmed	Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.	KCNH8 MYCBP2 MYO9A SPTB TM7SF3 OBSCN ETV1 ADCY3 PTK2 TTC19 TASOR2 ZNF462 RPTOR UTRN UBR2 DNAJC13 LIMD1 PATL1 PPP4R4 DNAH1 ANKRD44 SLC35A3 FAM13A USP40 MACF1 ELK3 PALS2	1.26e-07	1489	199	27	28611215
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	STAM2 CCDC8 MYCBP2 MYO9A ERC1 ITPRID2 MELK MEX3C PIK3R4 RPTOR SYNE2 UTRN HIPK4 LIMD1 PPFIBP1 PPP4R4 FAM13A MACF1 AHNAK2 KIF1C	1.36e-07	861	199	20	36931259
Pubmed	SR protein kinases promote splicing of nonconsensus introns.	MYCBP2 ERC1 PKD1L1 F5 HNRNPA1 SAFB CPLANE1 DNAJC13 RASGRF1 POLDIP3 SMCHD1 MACF1 PRKDC	1.91e-07	361	199	13	26167880
Pubmed	Transcriptome analysis of mouse stem cells and early embryos.	ZSCAN5DP HPSE2 RGL1 RPS6KA6 UTRN RAP1GDS1 COL12A1 ZSCAN4 SMCHD1 KIF16B UTP4 PDE4DIP PWWP3B	2.03e-07	363	199	13	14691545
Pubmed	The protein network surrounding the human telomere repeat binding factors TRF1, TRF2, and POT1.	MYO10 F5 SYNE2 PLOD2 UTRN HSPA4 POLDIP3 CHD8 BRD2 MACF1	2.28e-07	197	199	10	20811636
Pubmed	Loss of ER retention motif of AGR2 can impact mTORC signaling and promote cancer metastasis.	VAPB MYCBP2 ERC1 SPTA1 UGGT1 CLSTN2 HNRNPA1 SAFB ALDH18A1 UTRN HSPA4 CHD8 DNAH1 CCT8 MACF1 PRKDC PALS2 DISP1 AHNAK2	2.32e-07	807	199	19	30575818
Pubmed	RSPO-LGR4 functions via IQGAP1 to potentiate Wnt signaling.	MYCBP2 UGGT1 PTK2 NUP205 SAFB DNAJC13 SMCHD1 THOC2 PRKDC LRRFIP1	2.88e-07	202	199	10	24639526
Pubmed	Protein interaction network of the mammalian Hippo pathway reveals mechanisms of kinase-phosphatase interactions.	ERC1 TUBGCP2 TIPRL ALDH18A1 UTRN HSPA4 LIMD1 PPFIBP1 THOC2 ANKRD44 DNAJC11 UNK PRKDC KIF1C	3.38e-07	446	199	14	24255178
Pubmed	Proteomic Analysis Reveals a Role for RSK in p120-catenin Phosphorylation and Melanoma Cell-Cell Adhesion.	RPS6KA3 GCLM RPS6KA6 AKT1 PPFIBP1 TRIM33 IBTK DNAJC11 MACF1	3.92e-07	160	199	9	31678930
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	KDM3A ZSCAN12 MELK NUP205 TRANK1 PSME4 RPTOR SMCHD1 KIF16B CHD8 TRIM33 IBTK UNK RIMS2 MINDY1	4.63e-07	529	199	15	14621295
Pubmed	Identifying biological pathways that underlie primordial short stature using network analysis.	CCDC8 MYCBP2 UGGT1 ITPRID2 F5 HNRNPA1 NUP205 SAFB SYNE2 UTRN HSPA4 SF3B2 POLDIP3 SMCHD1 THOC2 PPP1R10 BRD2 UTP4 CCT8 MACF1 PRKDC	5.05e-07	1024	199	21	24711643
Pubmed	The human cytoplasmic dynein interactome reveals novel activators of motility.	VAPB HAUS6 ERC1 PKD1L1 DBI TUBGCP2 FHIP1B NUP205 GCLM CPLANE1 LIMD1 PPFIBP1 PATL1 CEP164 AP4E1 IBTK CCT8 UNK KIF1C	5.36e-07	853	199	19	28718761
Pubmed	Large-scale characterization of HeLa cell nuclear phosphoproteins.	KDM3A ERG MYCBP2 ITPRID2 SAFB PTPRC RPTOR SF3B2 ARHGEF6 DNAJC13 PATL1 THOC2 BRD2 FAM13A UNK ELK3 PRKDC LRRFIP1	5.85e-07	774	199	18	15302935
Pubmed	Expression pattern of the Rsk2, Rsk4 and Pdk1 genes during murine embryogenesis.	RPS6KA3 RPS6KA6 PDPK2P	7.35e-07	4	199	3	12711546
Pubmed	SRCAP complex promotes lung cancer progression by reprograming the oncogenic transcription of Hippo-YAP/TAZ signaling pathway.	KDM3A STAM2 HAUS6 MYCBP2 ERC1 TIPRL WIZ LIMD1 SMCHD1 CHD8 THOC2 PPP1R10 CCT8 PRKDC LRRFIP1	7.37e-07	549	199	15	38280479
Pubmed	Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.	VAPB RABEP2 STAM2 CCDC8 MYCBP2 ERC1 UGGT1 ITPRID2 TIPRL PTPRC WIZ SYNE2 ALDH18A1 PDP2 UTRN UBR2 DNAJC13 GRB2 PPP4R4 PPP1R10 BRD2	7.43e-07	1049	199	21	27880917
Pubmed	In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.	VAPB ERC1 SPTA1 SPEF2 LIN54 UGGT1 HNRNPA1 TASOR2 NUP205 SAFB SYNE2 ULK1 SMCHD1 PPP4R4 ZNF675 BRD2 GSTK1 AVIL DNAJC11 CSPG4 VPS35 MACF1 PABPC1L PRKDC RIMS2	8.73e-07	1442	199	25	35575683
Pubmed	Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.	MYCBP2 MYO9A MELK HNRNPA1 PTK2 NUP205 PIK3R4 SAFB PSME4 RPTOR ALDH18A1 UTRN HSPA4 SF3B2 DNAJC13 POLDIP3 SMCHD1 CHD8 UTP4 VPS35 CCT8 MACF1 PRKDC AHNAK2	9.89e-07	1353	199	24	29467282
Pubmed	Targeting USP10 induces degradation of oncogenic ANLN in esophageal squamous cell carcinoma.	CPNE2 ERC1 UGGT1 ITPRID2 TUBGCP2 F5 HNRNPA1 TASOR2 NUP205 SAFB ASCC2 ALDH18A1 SF3B2 POLDIP3 PPFIBP1 SMCHD1 THOC2 PPP1R10 UTP4 DNAJC11 CCT8 PRKDC LRRFIP1	1.00e-06	1257	199	23	36526897
Pubmed	Proteome-wide identification of HSP70/HSC70 chaperone clients in human cells.	VAPB LIN54 UGGT1 DBI TIPRL COPS2 HNRNPA1 NUP205 SAFB SYNE2 ALDH18A1 UTRN HSPA4 SF3B2 DNAJC13 RAP1GDS1 POLDIP3 GSTK1 PTRH2 CCT8 PRKDC VPS28 LRRFIP1 AHNAK2	1.18e-06	1367	199	24	32687490
Pubmed	FBXO22 promotes leukemogenesis by targeting BACH1 in MLL-rearranged acute myeloid leukemia.	RABEP2 MYO7A TOPAZ1 OBSCN COPS2 TTC19 PIK3R4 TRANK1 USP32 ASCC2 GRB2 PPP1R10 VPS35 MINDY1	1.22e-06	497	199	14	36774506
Pubmed	Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.	MYCBP2 UGGT1 TASOR2 NUP205 SYNE2 ALDH18A1 UTRN HSPA4 SF3B2 POLDIP3 SMCHD1 CHD8 THOC2 UTP4 MACF1 PRKDC	1.30e-06	653	199	16	22586326
Pubmed	Functional proteomics mapping of a human signaling pathway.	STAM2 MYCBP2 HIPK1 PTPRC ASCC2 UTRN PLEKHB2 LIMD1 ZSCAN4 ZNF675 PPP1R10 CSPG4 VPS35 PDE4DIP MACF1	1.83e-06	591	199	15	15231748
Pubmed	A protein-interaction network of interferon-stimulated genes extends the innate immune system landscape.	VAPB RPS6KA3 UGGT1 ITPRID2 TUBGCP2 COPS2 NUP205 EHD2 SYNE2 ASCC2 ALDH18A1 PLOD2 HSPA4 POLDIP3 PPFIBP1 GRB2 THOC2 VPS35 PTRH2 CCT8 PRKDC MX1 LRRFIP1 AHNAK2	2.90e-06	1440	199	24	30833792
Pubmed	The N6-methyladenosine-mediated lncRNA WEE2-AS1 promotes glioblastoma progression by stabilizing RPN2.	VAPB CPNE2 STAM2 PTK2 GCLM DNAJC13 PPFIBP1 GSTK1 CSPG4 PTRH2 PALS2	3.09e-06	325	199	11	36168628
Pubmed	Interactomes of Glycogen Synthase Kinase-3 Isoforms.	MYO9A ERC1 KIAA0586 UTRN LIMD1 PPFIBP1 IBTK UNK MACF1	3.61e-06	209	199	9	36779422
Pubmed	SIN1/MIP1 maintains rictor-mTOR complex integrity and regulates Akt phosphorylation and substrate specificity.	RPTOR AKT1 HSPA4	3.64e-06	6	199	3	16962653
Pubmed	An Interaction Landscape of Ubiquitin Signaling.	RABEP2 STAM2 LAMA1 COPS2 USP32 ASCC2 PDP2 PDPK2P IBTK RNF220 USP40 MACF1 VPS28	4.63e-06	481	199	13	28190767
Pubmed	Resolution of cell fate decisions revealed by single-cell gene expression analysis from zygote to blastocyst.	BNC2 ZNF346 ZSCAN12 ZSCAN5DP ETV1 ZNF354C ZNF462 KAT2B WIZ SF3B2 PLXNA1 LIMD1 PPP1R10 IBTK BRD2 ZKSCAN3 UNK	4.64e-06	808	199	17	20412781
Pubmed	Transcription factor protein interactomes reveal genetic determinants in heart disease.	VAPB HNRNPA1 TASOR2 ZNF462 SAFB WIZ DNMT3A POLDIP3 CHD8 TRIM33 BRD2 PRKDC	4.99e-06	411	199	12	35182466
Pubmed	Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.	VAPB STAM2 CCDC8 MYCBP2 UGGT1 ITPRID2 HNRNPA1 DMXL1 SYNE2 ASCC2 PLOD2 HSPA4 SF3B2 DNAJC13 PPFIBP1 KIF16B GRB2 VARS2 BRD2 UTP4 DNAJC11 VPS35 PTRH2 MACF1	5.00e-06	1487	199	24	33957083
Pubmed	Proximity biotinylation and affinity purification are complementary approaches for the interactome mapping of chromatin-associated protein complexes.	EPC2 HAUS6 MYCBP2 ERC1 GON4L F5 PHKG2 KAT2B UTRN ARHGEF6 DNMT3A SMCHD1 THOC2 PPP1R10 BRD2	5.27e-06	645	199	15	25281560
Pubmed	Paralog knockout profiling identifies DUSP4 and DUSP6 as a digenic dependence in MAPK pathway-driven cancers.	KDM3A KCNH8 HIPK1 RPS6KA3 GCK PTK2 DMXL1 KAT2B RPS6KA6 AKT1 ULK1 PLXNA1 DNAH10 GRB2 BRD2 TUBE1	5.37e-06	730	199	16	34857952
Pubmed	A genome-wide association study of chemotherapy-induced alopecia in breast cancer patients.	STAM2 ZNF462 TMEM132C CTH	5.77e-06	21	199	4	24025145
Pubmed	Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.	HAUS6 MYCBP2 ERC1 LIN54 ZNF462 WIZ UTRN DNAJC13 ZSCAN4 CHD8 ZKSCAN3 CCT8	5.92e-06	418	199	12	34709266
Pubmed	Mapping the Ku Interactome Using Proximity-Dependent Biotin Identification in Human Cells.	TIPRL WIZ SF3B2 POLDIP3 SMCHD1 CHD8 THOC2 PPP1R10 CCT8 PRKDC	6.00e-06	283	199	10	30585729
Pubmed	Mapping a dynamic innate immunity protein interaction network regulating type I interferon production.	BNC2 ZNF346 HAUS6 UGGT1 COPS2 RPTOR UBR2 GRB2 VPS35 PALS2	6.00e-06	283	199	10	21903422
Pubmed	Systems analysis of RhoGEF and RhoGAP regulatory proteins reveals spatially organized RAC1 signalling from integrin adhesions.	VAPB ZNF346 MYO9A UGGT1 CHN1 NUP205 FGD4 ALDH18A1 NKTR PLOD2 UTRN ARHGEF6 LIMD1 GRB2 PPP1R10 FAM13A UTP4 DNAJC11	6.17e-06	916	199	18	32203420
Pubmed	Tails of unconventional myosins.	MYO7A MYO9A MYO10	6.35e-06	7	199	3	11212352
Pubmed	ZZW-115-dependent inhibition of NUPR1 nuclear translocation sensitizes cancer cells to genotoxic agents.	UGGT1 ITPRID2 F5 HNRNPA1 NUP205 SAFB ALDH18A1 POLDIP3 SMCHD1 THOC2 BRD2 UTP4 MACF1 PRKDC LRRFIP1	6.93e-06	660	199	15	32780723
Pubmed	Human transcription factor protein interaction networks.	EPC2 CCDC8 ERG LIN54 GON4L NUP205 ZNF462 KAT2B WIZ SYNE2 HSPA4 LIMD1 DNAH10 POLDIP3 SMCHD1 CHD8 PATL1 TRIM33 BRD2 ZKSCAN3 UNK PABPC1L ELK3	8.35e-06	1429	199	23	35140242
Pubmed	KSHV episome tethering sites on host chromosomes and regulation of latency-lytic switch by CHD4.	KDM3A HNRNPA1 SAFB SF3B2 POLDIP3 THOC2 CCT8	1.05e-05	130	199	7	35545047
Pubmed	Defining the proximal interaction networks of Arf GTPases reveals a mechanism for the regulation of PLD1 and PI4KB.	SPATA7 HAUS6 CCDC8 LIN54 LRRK2 HNRNPA1 DMXL1 TASOR2 WIZ ALDH18A1 DNAJC13 PPFIBP1 AP4E1 TRIM33 CCT8 PRKDC	1.16e-05	777	199	16	35844135
Pubmed	Human Sos1: a guanine nucleotide exchange factor for Ras that binds to GRB2.	SPTA1 SPTB PTK2 GRB2	1.20e-05	25	199	4	8493579
Pubmed	BioID identifies novel c-MYC interacting partners in cultured cells and xenograft tumors.	EPC2 LIN54 WIZ SF3B2 CHD8 TRIM33 PPP1R10	1.28e-05	134	199	7	25452129
Pubmed	P90 Ribosomal s6 kinase 2 negatively regulates axon growth in motoneurons.	ERC1 RPS6KA3 AKT1	1.51e-05	9	199	3	19555761
Pubmed	The deacetylase SIRT1 promotes membrane localization and activation of Akt and PDK1 during tumorigenesis and cardiac hypertrophy.	KAT2B AKT1 PDPK2P	1.51e-05	9	199	3	21775285
Pubmed	Convergent proliferative response and divergent morphogenic pathways induced by epicardial and endocardial signaling in fetal heart development.	BMP10 AKT1 VCAM1	1.51e-05	9	199	3	15582777
Pubmed	BioID-based intact cell interactome of the Kv1.3 potassium channel identifies a Kv1.3-STAT3-p53 cellular signaling pathway.	VAPB STAM2 HAUS6 MYO9A ERC1 TIPRL HNRNPA1 GCLM ALDH18A1 HSPA4 SF3B2 PPFIBP1 CCT8 MACF1 PRKDC	1.58e-05	708	199	15	39231216
Pubmed	Large-scale mapping of human protein-protein interactions by mass spectrometry.	MYCBP2 ERC1 UGGT1 GAS8 TIPRL CMYA5 COPS2 MYCBPAP PTK2 NUP205 PIK3R4 GCLM ULK1 PLOD2 SF3B2 PLEKHB2 PPFIBP1 PKD1L3 IBTK GSTK1 VPS35	1.67e-05	1284	199	21	17353931
Pubmed	Protein interactome mining defines melatonin MT1 receptors as integral component of presynaptic protein complexes of neurons.	VAPB MYO9A ADCY3 PSME4 SYNE2 USP32 AP4E1 VPS35 MACF1 PRKDC	1.84e-05	322	199	10	26514267
Pubmed	Dependence of leucine-rich repeat kinase 2 (LRRK2) kinase activity on dimerization.	LRRK2 HSPA4 PRKDC	2.15e-05	10	199	3	19826009
Pubmed	Hsp70 associates with Rictor and is required for mTORC2 formation and activity.	RPTOR AKT1 HSPA4	2.15e-05	10	199	3	18505677
Pubmed	E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins.	MYO7A TOPAZ1 RNF112 LAMA1 OBSCN CHN1 NUP205 WIZ ALDH18A1 UTRN ZNF675 CCT8 PWWP3B PRKDC TUBE1	2.48e-05	736	199	15	29676528
Pubmed	Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.	VAPB UGGT1 KIAA0586 CMYA5 HNRNPA1 NUP205 PIK3R4 SAFB RPTOR ALDH18A1 HSPA4 SF3B2 PLXNA1 DNAH10 POLDIP3 SMCHD1 THOC2 UTP4 DNAJC11 VPS35 CCT8 PRKDC	2.51e-05	1425	199	22	30948266
Pubmed	Prediction of the coding sequences of unidentified human genes. XVIII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.	HAUS6 OBSCN GON4L KIF16B CHD8 PPP4R4	2.63e-05	101	199	6	10997877
Pubmed	A human MAP kinase interactome.	MYO9A HIPK1 ITPRID2 PTK2 RGL1 NKTR CPLANE1 RAP1GDS1 GRB2 CHD8 MACF1 PRKDC	2.64e-05	486	199	12	20936779
Pubmed	Systematic Analysis of Human Protein Phosphatase Interactions and Dynamics.	MYO9A TIPRL NUP205 PHKG2 UTRN HSPA4 SF3B2 LIMD1 GRB2 ANKRD44 PPP1R10 CCT8 PRKDC	2.93e-05	573	199	13	28330616
Pubmed	mTORC1/2 signaling is downregulated by amino acid-free culture of mouse preimplantation embryos and is only partially restored by amino acid readdition.	RPTOR AKT1 PDPK2P	2.94e-05	11	199	3	33052068
Pubmed	MTORC1-mediated NRBF2 phosphorylation functions as a switch for the class III PtdIns3K and autophagy.	PIK3R4 RPTOR ULK1	2.94e-05	11	199	3	28059666
Pubmed	Cell cycle-dependent phosphorylation regulates RECQL4 pathway choice and ubiquitination in DNA double-strand break repair.	VAPB ZNF346 CCDC8 UGGT1 TIPRL COPS2 HNRNPA1 NUP205 ASCC2 ALDH18A1 PLOD2 HSPA4 SF3B2 POLDIP3 GRB2 RNF220 WDR87 VPS35 PTRH2 CCT8 PRKDC	2.95e-05	1335	199	21	29229926
Pubmed	Impaired plasma membrane localization of ubiquitin ligase complex underlies 3-M syndrome development.	CCDC8 MYO7A TASOR2 NUP205 DNAJC13 POLDIP3 PPFIBP1 DNAH1 USP40 MACF1 DISP1 KIF1C	3.21e-05	496	199	12	31343991
Pubmed	PKBalpha/Akt1 acts downstream of DNA-PK in the DNA double-strand break response and promotes survival.	AKT1 PRKDC	3.26e-05	2	199	2	18439899
Pubmed	LRRK2 directly phosphorylates Akt1 as a possible physiological substrate: impairment of the kinase activity by Parkinson's disease-associated mutations.	LRRK2 AKT1	3.26e-05	2	199	2	21658387
Pubmed	beta1-Integrins induce phosphorylation of Akt on serine 473 independently of focal adhesion kinase and Src family kinases.	PTK2 AKT1	3.26e-05	2	199	2	15309026
Pubmed	Beta-spectrin Promiss-ao: a translation initiation codon mutation of the beta-spectrin gene (ATG --> GTG) associated with hereditary spherocytosis and spectrin deficiency in a Brazilian family.	SPTA1 SPTB	3.26e-05	2	199	2	9414314
Pubmed	Mutation of a highly conserved residue of betaI spectrin associated with fatal and near-fatal neonatal hemolytic anemia.	SPTA1 SPTB	3.26e-05	2	199	2	9005995
Pubmed	Akt1 binds focal adhesion kinase via the Akt1 kinase domain independently of the pleckstrin homology domain.	PTK2 AKT1	3.26e-05	2	199	2	26579576
Pubmed	DNA damage promotes microtubule dynamics through a DNA-PK-AKT axis for enhanced repair.	AKT1 PRKDC	3.26e-05	2	199	2	33404607
Pubmed	Cooperation between ETS transcription factor ETV1 and histone demethylase JMJD1A in colorectal cancer.	KDM3A ETV1	3.26e-05	2	199	2	33174020
Pubmed	SMCHD1 terminates the first embryonic genome activation event in mouse two-cell embryos and contributes to a transcriptionally repressive state.	ZSCAN4 SMCHD1	3.26e-05	2	199	2	31365290
Pubmed	DNA-PK mediates AKT activation and apoptosis inhibition in clinically acquired platinum resistance.	AKT1 PRKDC	3.26e-05	2	199	2	22131882
Pubmed	An insertional frameshift mutation of the beta-spectrin gene associated with elliptocytosis in spectrin nice (beta 220/216).	SPTA1 SPTB	3.26e-05	2	199	2	2070088
Pubmed	Dopaminergic neurodegeneration induced by Parkinson's disease-linked G2019S LRRK2 is dependent on kinase and GTPase activity.	LRRK2 VPS35	3.26e-05	2	199	2	32631998
Pubmed	The serine/threonine kinase ULK1 is a target of multiple phosphorylation events.	AKT1 ULK1	3.26e-05	2	199	2	21819378
Pubmed	Thrombosis and secondary hemochromatosis play major roles in the pathogenesis of jaundiced and spherocytic mice, murine models for hereditary spherocytosis.	SPTA1 SPTB	3.26e-05	2	199	2	9373273
Pubmed	The C-terminal region of the focal adhesion kinase F1 domain binds Akt1 and inhibits pressure-induced cell adhesion.	PTK2 AKT1	3.26e-05	2	199	2	28820394
Pubmed	NG2 expression in microglial cells affects the expression of neurotrophic and proinflammatory factors by regulating FAK phosphorylation.	PTK2 CSPG4	3.26e-05	2	199	2	27306838
Pubmed	Spectrin mutations in hereditary elliptocytosis and hereditary spherocytosis.	SPTA1 SPTB	3.26e-05	2	199	2	8844207
Pubmed	MicroRNA-7 inhibits cell proliferation, migration and invasion in human non-small cell lung cancer cells by targeting FAK through ERK/MAPK signaling pathway.	LILRB1 PTK2	3.26e-05	2	199	2	27764812
Pubmed	Regulation of profibrotic responses by ADAM17 activation in high glucose requires its C-terminus and FAK.	PTK2 ADAM17	3.26e-05	2	199	2	29361535
Pubmed	Structural and functional heterogeneity of alpha spectrin mutations involving the spectrin heterodimer self-association site: relationships to hematologic expression of homozygous hereditary elliptocytosis and hereditary pyropoikilocytosis.	SPTA1 SPTB	3.26e-05	2	199	2	2346784
Pubmed	YK-4-279 inhibits ERG and ETV1 mediated prostate cancer cell invasion.	ERG ETV1	3.26e-05	2	199	2	21559405
Pubmed	ULK1 and JNK are involved in mitophagy incurred by LRRK2 G2019S expression.	LRRK2 ULK1	3.26e-05	2	199	2	27023913
Pubmed	Stimulated shedding of vascular cell adhesion molecule 1 (VCAM-1) is mediated by tumor necrosis factor-alpha-converting enzyme (ADAM 17).	ADAM17 VCAM1	3.26e-05	2	199	2	12878595
Pubmed	Akt directly regulates focal adhesion kinase through association and serine phosphorylation: implication for pressure-induced colon cancer metastasis.	PTK2 AKT1	3.26e-05	2	199	2	21209368
Pubmed	Targeting of AKT1 enhances radiation toxicity of human tumor cells by inhibiting DNA-PKcs-dependent DNA double-strand break repair.	AKT1 PRKDC	3.26e-05	2	199	2	18644989
Pubmed	Properties of human red cell spectrin heterodimer (side-to-side) assembly and identification of an essential nucleation site.	SPTA1 SPTB	3.26e-05	2	199	2	1634521
Pubmed	HSPA4 regulated glioma progression via activation of AKT signaling pathway.	AKT1 HSPA4	3.26e-05	2	199	2	37339521
Pubmed	Combinatorial activation of FAK and AKT by transforming growth factor-beta1 confers an anoikis-resistant phenotype to myofibroblasts.	PTK2 AKT1	3.26e-05	2	199	2	17113264
Pubmed	Basonuclins 1 and 2, whose genes share a common origin, are proteins with widely different properties and functions.	BNC2 BNC1	3.26e-05	2	199	2	16891417
Pubmed	A deletional frameshift mutation of the beta-spectrin gene associated with elliptocytosis in spectrin Tokyo (beta 220/216).	SPTA1 SPTB	3.26e-05	2	199	2	1391962
Pubmed	Increased Phospho-AKT in Blood Cells from LRRK2 G2019S Mutation Carriers.	LRRK2 AKT1	3.26e-05	2	199	2	35929078
Pubmed	Chaperone activity and prodan binding at the self-associating domain of erythroid spectrin.	SPTA1 SPTB	3.26e-05	2	199	2	15492010
Interaction	YWHAG interactions	VAPB STAM2 CCDC8 MYCBP2 MYO9A ERC1 RPS6KA3 LRRK2 ITPRID2 MELK PTK2 PIK3R4 RPTOR SYNE2 AKT1 NKTR ULK1 UTRN HSPA4 ARHGEF6 FOXO6 LIMD1 PPFIBP1 GRB2 PPP4R4 FAM13A UNK MACF1 PRKDC PDE7B AHNAK2 KIF1C	3.99e-07	1248	195	32	int:YWHAG
Interaction	YWHAH interactions	VAPB STAM2 CCDC8 MYCBP2 MYO9A ERC1 RPS6KA3 LRRK2 ITPRID2 MELK MEX3C PIK3R4 RPTOR SYNE2 NKTR UTRN HSPA4 ARHGEF6 FOXO6 LIMD1 PPFIBP1 GRB2 PPP4R4 FAM13A MACF1 RIMS2 AHNAK2 KIF1C	2.78e-06	1102	195	28	int:YWHAH
Interaction	CALM1 interactions	CCDC8 MYCBP2 MYO7A MYO10 LRRK2 OBSCN ITPRID2 DMXL1 PHKG2 GCLM SYNE2 AKT1 UTRN HSPA4 DNAJC13 TRIM33 PDE4DIP UNK TRPV4 KIF1C	3.07e-06	626	195	20	int:CALM1
Interaction	YWHAE interactions	VAPB CCDC8 MYCBP2 MYO9A ERC1 LRRK2 ITPRID2 MELK HNRNPA1 MEX3C PIK3R4 RPTOR AKT1 ULK1 HSPA4 SF3B2 VCAM1 UBR2 RAP1GDS1 RASGRF1 PPFIBP1 GRB2 PPP4R4 FAM13A UNK MACF1 RIMS2 PDE7B KIF1C	1.15e-05	1256	195	29	int:YWHAE
Interaction	YWHAB interactions	VAPB MYCBP2 MYO9A ERC1 RPS6KA3 LRRK2 ITPRID2 MELK HNRNPA1 PIK3R4 USP32 HSPA4 VCAM1 FOXO6 RASGRF1 PPFIBP1 GRB2 PPP4R4 TRIM33 FAM13A UNK MACF1 PDE7B AHNAK2 KIF1C	1.67e-05	1014	195	25	int:YWHAB
GeneFamily	Pleckstrin homology domain containing\|Rho guanine nucleotide exchange factors\|C2 domain containing	MYO10 SPTB FGD4 AKT1 ARHGEF6 PLEKHB2 RASGRF1	9.11e-04	206	135	7	682
GeneFamily	EF-hand domain containing\|Spectrins	SPTA1 SPTB	1.13e-03	7	135	2	1113
GeneFamily	ETS transcription factor family	ERG ETV1 ELK3	1.16e-03	28	135	3	534
GeneFamily	Pleckstrin homology domain containing\|Rho guanine nucleotide exchange factors\|C2 domain containing	OBSCN FGD4 ARHGEF6 RASGRF1	1.50e-03	66	135	4	722
Coexpression	ONKEN_UVEAL_MELANOMA_UP	WWC3 HNRNPA1 ADCY3 PTK2 MEX3C DMXL1 PTPRC PSME4 SYNE2 NIPA2 ADAM17 DNAJC13 RAP1GDS1 SMCHD1 TRIM33 PPP1R10 RRN3 CSPG4 PDE4DIP PTRH2 MACF1 PRKDC VPS28 LRRFIP1 AHNAK2	1.65e-09	790	198	25	M12490
Coexpression	DACOSTA_UV_RESPONSE_VIA_ERCC3_DN	KDM3A MYCBP2 MYO10 ERC1 RPS6KA3 TIPRL MELK PTK2 PIK3R4 RGL1 PSME4 SYNE2 ADAM17 PLOD2 UBR2 DNAJC13 SMCHD1 THOC2 TRIM33 IBTK SLC35A3 MACF1 PALS2 LRRFIP1	3.62e-08	856	198	24	M4500
Coexpression	GSE27241_WT_VS_RORGT_KO_TH17_POLARIZED_CD4_TCELL_TREATED_WITH_DIGOXIN_UP	MYO10 ERC1 NUP205 ULK1 UTRN TRIM33 PPP1R10 MACF1 PWWP3B	9.80e-06	180	198	9	M8239
Coexpression	GSE11057_EFF_MEM_VS_CENT_MEM_CD4_TCELL_DN	MYCBP2 PIWIL1 MYCBPAP F5 PTK2 CCDC110 FAM13A MACF1 PDE7B	1.45e-05	189	198	9	M3112
Coexpression	BUYTAERT_PHOTODYNAMIC_THERAPY_STRESS_UP	KDM3A HAUS6 MYO9A GON4L COPS2 RGL1 GCLM ADAM17 ULK1 HSPA4 PLEKHB2 UBR2 TRIM33 IBTK BRD2 FAM13A PDE4DIP CTH AHNAK2	1.66e-05	822	198	19	M6782
Coexpression	GSE46606_DAY1_VS_DAY3_CD40L_IL2_IL5_STIMULATED_IRF4MID_BCELL_DN	UPB1 HIPK1 ITPRID2 TIPRL PLOD2 ARHGEF6 PLEKHB2 UBR2 LIMD1	2.27e-05	200	198	9	M9842
Coexpression	EBAUER_TARGETS_OF_PAX3_FOXO1_FUSION_UP	MYO10 CLSTN2 UTRN ARHGEF6 FAM13A ARSF PDE4DIP MACF1 AHNAK2	2.27e-05	200	198	9	M78
Coexpression	GSE27896_HDAC6_KO_VS_WT_TREG_UP	MYO9A MEX3C KAT2B SAFB UTRN THOC2 BRD2 LRRFIP1	6.06e-05	176	198	8	M8248
Coexpression	HOEBEKE_LYMPHOID_STEM_CELL_UP	KDM3A HNRNPA1 UBR2 TRIM33 MACF1 LRRFIP1	9.62e-05	97	198	6	M14698
Coexpression	GSE21033_1H_VS_12H_POLYIC_STIM_DC_DN	EPC2 STAM2 SMYD1 PTK2 NKTR EMB SLC35A3	1.02e-04	141	198	7	M7720
Coexpression	GSE19888_ADENOSINE_A3R_ACT_VS_TCELL_MEMBRANES_ACT_IN_MAST_CELL_DN	NKTR ULK1 SF3B2 DNMT3A PATL1 AP4E1 RNF220 DNAJC11	1.03e-04	190	198	8	M7317
Coexpression	GSE21063_3H_VS_16H_ANTI_IGM_STIM_BCELL_DN	WWC3 ERC1 TM7SF3 KAT2B USP32 AKT1 ARHGEF6 DNAJC13	1.33e-04	197	198	8	M8271
Coexpression	GSE41176_UNSTIM_VS_ANTI_IGM_STIM_BCELL_3H_DN	TRIT1 KIAA0586 DMXL1 KAT2B DNAJC13 LIMD1 FAM13A MACF1	1.33e-04	197	198	8	M9916
Coexpression	GSE25088_ROSIGLITAZONE_VS_IL4_AND_ROSIGLITAZONE_STIM_STAT6_KO_MACROPHAGE_DAY10_UP	WWC3 HIPK1 F5 TRANK1 PTPRC SYNE2 AKT1 ULK1	1.38e-04	198	198	8	M7948
Coexpression	GSE25087_TREG_VS_TCONV_ADULT_UP	UGGT1 CHN1 ADCY3 KAT2B PARPBP UTRN SMCHD1 IBTK	1.42e-04	199	198	8	M4650
Coexpression	GSE22432_MULTIPOTENT_VS_COMMON_DC_PROGENITOR_UP	VAPB MYO7A RPS6KA3 GAS8 RAP1GDS1 RRN3 UTP4 PDE4DIP	1.42e-04	199	198	8	M7821
Coexpression	GSE40666_UNTREATED_VS_IFNA_STIM_STAT4_KO_EFFECTOR_CD8_TCELL_90MIN_DN	WWC3 MYO9A SPEF2 PTK2 UTRN PPFIBP1 HELQ DISP1	1.42e-04	199	198	8	M9236
Coexpression	GSE27786_LIN_NEG_VS_BCELL_DN	EHD2 SYNE2 SF3B2 POLDIP3 THOC2 CEP164 PDE4DIP KIF1C	1.47e-04	200	198	8	M4768
Coexpression	GSE45881_CXCR6HI_VS_CXCR1LO_COLONIC_LAMINA_PROPRIA_UP	NUP205 PTPRC PSME4 NKTR ULK1 PLEKHB2 THOC2 MACF1	1.47e-04	200	198	8	M9889
Coexpression	GSE18281_SUBCAPSULAR_VS_PERIMEDULLARY_CORTICAL_REGION_OF_THYMUS_UP	MYO7A MYO9A HIPK1 UGGT1 ETV1 VCAM1 GSTK1 KIF1C	1.47e-04	200	198	8	M7235
Coexpression	GSE22140_GERMFREE_VS_SPF_ARTHRITIC_MOUSE_CD4_TCELL_UP	MYO7A ADCY3 DMXL1 RGL1 GCLM IBTK ELK3 MX1	1.47e-04	200	198	8	M7649
Coexpression	HAMAI_APOPTOSIS_VIA_TRAIL_UP	HAUS6 MYCBP2 MYO9A MYO10 TM7SF3 DMXL1 TASOR2 SYNE2 NKTR CPLANE1 PARPBP DNAJC13 SMCHD1 KIF16B TRIM33	1.49e-04	656	198	15	M18979
CoexpressionAtlas	DevelopingGonad_e14.5_ epididymis_emap-29141_top-relative-expression-ranked_1000	VAPB BNC2 ETV1 CLSTN2 FHIP1B DMXL1 ZNF462 TMEM132C BNC1 RGL1 SYNE2 NKTR CPLANE1 PLOD2 UTRN DNMT3A DNAJC13 CHD8 THOC2 BRD2 ZKSCAN3 USP40 TUBE1	9.47e-07	801	191	23	gudmap_developingGonad_e14.5_ epididymis_1000
CoexpressionAtlas	DevelopingGonad_e12.5_epididymis_emap-29139_top-relative-expression-ranked_1000	VAPB BNC2 MYO10 KIAA0586 DMXL1 ZNF462 BNC1 RGL1 SYNE2 NKTR CPLANE1 PLOD2 UTRN DNMT3A DNAJC13 CHD8 THOC2 LEFTY2 BRD2 ZKSCAN3 USP40 TUBE1	3.77e-06	806	191	22	gudmap_developingGonad_e12.5_epididymis_1000
CoexpressionAtlas	DevelopingGonad_e14.5_ epididymis_emap-29141_top-relative-expression-ranked_500	VAPB BNC2 DMXL1 BNC1 RGL1 SYNE2 NKTR CPLANE1 PLOD2 UTRN DNMT3A DNAJC13 CHD8 ZKSCAN3 TUBE1	5.33e-06	413	191	15	gudmap_developingGonad_e14.5_ epididymis_500
CoexpressionAtlas	DevelopingGonad_e11.5_ovary + mesonephros_emap-3226_k-means-cluster#2_top-relative-expression-ranked_1000	VAPB KIAA0586 CLSTN2 SYNE2 RPS6KA6 NKTR CPLANE1 UTRN DNMT3A DNAJC13 CHD8 THOC2 TUBE1	7.74e-06	323	191	13	gudmap_developingGonad_e11.5_ovary + mesonephros_k2_1000
CoexpressionAtlas	DevelopingGonad_e16.5_epididymis_emap-29702_top-relative-expression-ranked_1000	VAPB BNC2 FHIP1B DMXL1 ZNF462 TMEM132C BNC1 SYNE2 NKTR CPLANE1 PLOD2 UTRN DNMT3A DNAJC13 CHD8 THOC2 BRD2 ZKSCAN3 USP40 TUBE1 AHNAK2	9.51e-06	790	191	21	gudmap_developingGonad_e16.5_epididymis_1000
CoexpressionAtlas	DevelopingGonad_e11.5_ovary + mesonephros_emap-3226_top-relative-expression-ranked_1000	VAPB BNC2 SPTA1 KIAA0586 CLSTN2 DMXL1 ZNF462 BNC1 RGL1 SYNE2 RPS6KA6 NKTR CPLANE1 UTRN DNMT3A DNAJC13 CHD8 THOC2 BRD2 ZKSCAN3 TUBE1	1.52e-05	815	191	21	gudmap_developingGonad_e11.5_ovary + mesonephros_1000
CoexpressionAtlas	DevelopingGonad_e16.5_epididymis_emap-29702_k-means-cluster#4_top-relative-expression-ranked_1000	DMXL1 BNC1 SYNE2 CPLANE1 DNAJC13 CHD8 THOC2 USP40	1.99e-05	127	191	8	gudmap_developingGonad_e16.5_epididymis_1000_k4
CoexpressionAtlas	DevelopingKidney_e15.5_Medullary collecting duct_emap-28063_k-means-cluster#4_top-relative-expression-ranked_1000	MYCBP2 MYO10 GON4L TTC19 CPLANE1 PARPBP UTRN CEP164 IBTK SLC35A3 LRRFIP1	2.58e-05	261	191	11	gudmap_developingKidney_e15.5_Medullary collecting duct_1000_k4
CoexpressionAtlas	FacebaseRNAseq_e10.5_Lateral Nasal Eminence_top-relative-expression-ranked_2500_k-means-cluster#1	SPATA7 ZSCAN12 MYO9A ERC1 HIPK1 LIN54 KIAA0586 GON4L CHN1 C17orf75 SYNE2 RPS6KA6 NKTR CPLANE1 HSPA4 UBR2 HELQ CEP164 ZKSCAN3 MACF1	2.62e-05	780	191	20	Facebase_RNAseq_e10.5_Lateral Nasal Eminence_2500_K1
CoexpressionAtlas	dev gonad_e13.5_F_MeioticGermCell_Oct_k-means-cluster#4_top-relative-expression-ranked_1000	MYO9A TRANK1 USP32 PPP4R4 USP40	3.22e-05	41	191	5	gudmap_dev gonad_e13.5_F_MeioticGermCell_Oct_k4_1000
CoexpressionAtlas	DevelopingGonad_e18.5_epididymis_emap-13166_top-relative-expression-ranked_1000	VAPB BNC2 ETV1 DMXL1 ZNF462 TMEM132C SYNE2 NKTR CPLANE1 PLOD2 UTRN DNMT3A DNAJC13 COL12A1 CHD8 THOC2 BRD2 ZKSCAN3 TUBE1 AHNAK2	3.68e-05	799	191	20	gudmap_developingGonad_e18.5_epididymis_1000
CoexpressionAtlas	DevelopingGonad_e14.5_ epididymis_emap-29141_k-means-cluster#3_top-relative-expression-ranked_1000	CLSTN2 DMXL1 SYNE2 NKTR CPLANE1 UTRN DNMT3A DNAJC13 CHD8 THOC2 USP40	4.15e-05	275	191	11	gudmap_developingGonad_e14.5_ epididymis_1000_k3
CoexpressionAtlas	DevelopingGonad_e16.5_ovary_emap-9563_k-means-cluster#2_top-relative-expression-ranked_1000	SPTA1 KIAA0586 SYNE2 NKTR CPLANE1 UTRN DNMT3A DNAJC13 CHD8 THOC2	4.64e-05	230	191	10	gudmap_developingGonad_e16.5_ovary_1000_k2
CoexpressionAtlas	DevelopingGonad_e16.5_epididymis_emap-29702_k-means-cluster#3_top-relative-expression-ranked_500	DMXL1 BNC1 SYNE2 CPLANE1 CHD8	5.10e-05	45	191	5	gudmap_developingGonad_e16.5_epididymis_500_k3
CoexpressionAtlas	DevelopingLowerUrinaryTract_e14.5_ urethra_emap-30902_k-means-cluster#4_top-relative-expression-ranked_1000	ERG RPS6KA3 GAS2 ETV1 TASOR2 TMEM132C BNC1 ANKRD44	5.68e-05	147	191	8	DevelopingLowerUrinaryTract_e14.5_ urethra_emap-30902_k4_1000
CoexpressionAtlas	DevelopingKidney_e15.5_Peripheral blastema_emap-27731_k-means-cluster#4_top-relative-expression-ranked_1000	GAS2 LRRK2 VCAM1 CTH	6.92e-05	25	191	4	gudmap_developingKidney_e15.5_Peripheral blastema_1000_k4
CoexpressionAtlas	FacebaseRNAseq_e9.5_Mandibular Arch_top-relative-expression-ranked_1000_k-means-cluster#4	SPATA7 EPC2 HAUS6 KIAA0586 SYNE2 RPS6KA6 ADAM17 UTRN MACF1	9.62e-05	203	191	9	Facebase_RNAseq_e9.5_Mandibular Arch_1000_K4
CoexpressionAtlas	DevelopingGonad_P2_epididymis_emap-30199_k-means-cluster#4_top-relative-expression-ranked_1000	CLSTN2 DMXL1 SYNE2 CPLANE1 CHD8 THOC2	1.63e-04	90	191	6	gudmap_developingGonad_P2_epididymis_1000_k4
CoexpressionAtlas	FacebaseRNAseq_e9.5_Mandibular Arch_top-relative-expression-ranked_2500_k-means-cluster#2	SPATA7 EPC2 HAUS6 MYCBP2 KIAA0586 GAS8 PIK3R4 RPS6KA6 PARPBP UTRN SMCHD1 THOC2 AP4E1 TRIM33 MACF1	1.88e-04	564	191	15	Facebase_RNAseq_e9.5_Mandibular Arch_2500_K2
CoexpressionAtlas	DevelopingGonad_e14.5_ ovary_emap-6699_k-means-cluster#3_top-relative-expression-ranked_1000	MYO9A RPS6KA6 NKTR CPLANE1 UTRN DNAJC13 CHD8 THOC2 ZKSCAN3	2.09e-04	225	191	9	gudmap_developingGonad_e14.5_ ovary_1000_k3
CoexpressionAtlas	DevelopingGonad_e18.5_epididymis_emap-13166_k-means-cluster#3_top-relative-expression-ranked_1000	VAPB TMEM132C SYNE2 NKTR UTRN DNMT3A DNAJC13 COL12A1 ZKSCAN3 TUBE1	2.41e-04	281	191	10	gudmap_developingGonad_e18.5_epididymis_1000_k3
CoexpressionAtlas	DevelopingGonad_e12.5_epididymis_emap-29139_k-means-cluster#5_top-relative-expression-ranked_1000	DMXL1 BNC1 SYNE2 CPLANE1 CHD8 THOC2 USP40	2.56e-04	138	191	7	gudmap_developingGonad_e12.5_epididymis_k5_1000
CoexpressionAtlas	DevelopingLowerUrinaryTract_e14.5_ bladder_emap-30872_k-means-cluster#5_top-relative-expression-ranked_1000	BNC2 MYO10 ETV1 C17orf75 RPTOR CPLANE1 UTRN DNMT3A IBTK SLC35A3 TUBE1 PDE7B	2.66e-04	397	191	12	gudmap_developingLowerUrinaryTract_e14.5_ bladder_1000_k5
CoexpressionAtlas	DevelopingKidney_e15.5_Medullary collecting duct_emap-28063_top-relative-expression-ranked_1000	MYCBP2 MYO10 GON4L F5 TTC19 FGD4 PDP2 CPLANE1 PARPBP UTRN LIMD1 CEP164 IBTK SLC35A3 TRPV4 CTH PDE7B LRRFIP1	2.74e-04	786	191	18	gudmap_developingKidney_e15.5_Medullary collecting duct_1000
CoexpressionAtlas	DevelopingGonad_P2_epididymis_emap-30199_top-relative-expression-ranked_1000	VAPB BNC2 ETV1 CLSTN2 DMXL1 TMEM132C SYNE2 NKTR CPLANE1 UTRN DNMT3A DNAJC13 COL12A1 CHD8 THOC2 BRD2 TUBE1 AHNAK2	3.24e-04	797	191	18	gudmap_developingGonad_P2_epididymis_1000
CoexpressionAtlas	DevelopingGonad_e16.5_epididymis_emap-29702_top-relative-expression-ranked_500	BNC2 DMXL1 TMEM132C BNC1 SYNE2 NKTR CPLANE1 UTRN DNAJC13 CHD8 ZKSCAN3 TUBE1	3.25e-04	406	191	12	gudmap_developingGonad_e16.5_epididymis_500
CoexpressionAtlas	FacebaseRNAseq_e10.5_Neural Epithelium Overlying Central Eminence_top-relative-expression-ranked_1000_k-means-cluster#4	CPNE2 EPC2 MYO10 KIAA0586 FGD4 MANEAL SYNE2 HSPA4 CHD8 RIMS2	3.84e-04	298	191	10	Facebase_RNAseq_e10.5_Neural Epithelium Overlying Central Eminence_1000_K4
CoexpressionAtlas	DevelopingGonad_e11.5_ovary + mesonephros_emap-3226_top-relative-expression-ranked_500	BNC2 SPTA1 CLSTN2 DMXL1 ZNF462 BNC1 RGL1 SYNE2 DNMT3A CHD8 ZKSCAN3 TUBE1	4.13e-04	417	191	12	gudmap_developingGonad_e11.5_ovary + mesonephros_500
CoexpressionAtlas	DevelopingGonad_e14.5_ epididymis_emap-29141_k-means-cluster#2_top-relative-expression-ranked_500	DMXL1 SYNE2 NKTR CPLANE1 DNAJC13 CHD8	4.17e-04	107	191	6	gudmap_developingGonad_e14.5_ epididymis_500_k2
CoexpressionAtlas	DevelopingKidney_e15.5_S-shaped body_emap-27855_k-means-cluster#5_top-relative-expression-ranked_1000	MYCBP2 MYO10 FHIP1B TTC19 PARPBP LIMD1 MACF1	4.61e-04	152	191	7	gudmap_developingKidney_e15.5_S-shaped body_1000_k5
CoexpressionAtlas	DevelopingGonad_P2_epididymis_emap-30199_k-means-cluster#4_top-relative-expression-ranked_200	DMXL1 SYNE2 CHD8	5.29e-04	18	191	3	gudmap_developingGonad_P2_epididymis_200_k4
ToppCell	10x5'-GI_small-bowel-Lymphocytic_T_CD4-T_CD4/CD8\|GI_small-bowel / Manually curated celltypes from each tissue	HIPK1 TASOR2 PTPRC SYNE2 NKTR UTRN SMCHD1 ANKRD44 PPP1R10 FAM13A MACF1	9.37e-10	188	199	11	ab9b725d6e0cdab8e9ddda6dee09e14730e9a578
ToppCell	LPS_IL1RA-Endothelial-Endothelial-Activated_Alv_Cap\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	ERG MYCBPAP PTK2 EHD2 SYNE2 SMCHD1 MACF1 CTH ELK3 DISP1 MX1	1.80e-09	200	199	11	79e51afb57ca38aacebd0298e5e727b55c0cfff9
ToppCell	droplet-Liver-Hepatocytes-24m-Myeloid-Kupffer_cell\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CCDC8 MYO9A ADCY3 ADAM17 PLXNA1 VCAM1 PLEKHB2 RAP1GDS1 DNAH10 MX1	3.50e-09	163	199	10	8dc0128eeede933537e3bcc5d6ec0322711552f3
ToppCell	droplet-Liver-Hepatocytes-24m-Myeloid-Kupffer_cell\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CCDC8 MYO9A ADCY3 ADAM17 PLXNA1 VCAM1 PLEKHB2 RAP1GDS1 DNAH10 MX1	3.50e-09	163	199	10	fd243ca223079033be480a24817a399f281fa4d4
ToppCell	mild\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	MYCBP2 PTPRC SYNE2 NKTR UTRN UBR2 SMCHD1 ANKRD44 MACF1 MX1	2.48e-08	200	199	10	12f1685ce8f218433068e090c9d839cd5a1910bf
ToppCell	saliva-Mild-Moderate_progression_d12-25-Myeloid-Granulocytic-Neutrophil-Neu_c2-CXCR4(low)\|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)	LRRK2 TRANK1 PTPRC USP32 UBR2 SMCHD1 DNAH1 ANKRD44 PRKDC	2.77e-08	151	199	9	b698ddc74565d47892c09c3f16d78038da2dd5e7
ToppCell	droplet-Liver-Hepatocytes-24m-Myeloid\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CCDC8 MYO9A PTPRC ADAM17 PLXNA1 PLEKHB2 RAP1GDS1 DNAH10 MX1	3.89e-08	157	199	9	ec433d2fe827abdb647be4176c231b7052482b6f
ToppCell	CV-Moderate-7\|CV / Virus stimulation, Condition and Cluster	MYCBP2 PTPRC PDP2 VCAM1 UBR2 SMCHD1 ANKRD44 MACF1 PRKDC	1.66e-07	186	199	9	8571956890fc9894d766ba294a28e376b4aba428
ToppCell	renal_cortex_nuclei-Adult_normal_reference\|renal_cortex_nuclei / Celltypes from Cells and Nuclei per compartment and clinical group	UPB1 MYO10 TM7SF3 FGD4 SYNE2 NKTR KIF16B THOC2 ACSM2B	1.90e-07	189	199	9	a48df46274d51e84ffb40264646de7346104efb9
ToppCell	MS-CD8-antiviral_CD4\|MS / Condition, Cell_class and T cell subcluster	RABEP2 TRIT1 MELK GCLM LRP5L HSPA4 HELQ PABPC1L MX1	1.99e-07	190	199	9	8c831c4560b8e70f92b4c15644fea39f7f7afcf2
ToppCell	LPS_IL1RA_TNF\|World / Treatment groups by lineage, cell group, cell type	LRRK2 ETV1 PXDNL PLOD2 UTRN VARS2 PPP1R10 FAM13A MX1	2.70e-07	197	199	9	0a6550dce156fc81f15b1e7830d331ca50d87d06
ToppCell	Control-Control-Lymphocyte-T/NK-NK_activated\|Control / Disease, condition lineage and cell class	ZNF354C MEX3C TRANK1 SYNE2 UTRN NPTXR MACF1 PABPC1L MX1	2.82e-07	198	199	9	76d5fe4e5bbe6c73a6ca409b80b5c3924e07cab7
ToppCell	systemic_lupus_erythematosus-flare\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	HNRNPA1 TTC19 PTPRC SYNE2 NKTR EMB SMCHD1 MACF1 MX1	2.82e-07	198	199	9	4c93ee921d56132d80832d8e94563f32ccf13bbc
ToppCell	LPS_IL1RA-Endothelial-Endothelial-Gen_Cap\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	ERG SPEF2 ITPRID2 SYNE2 NKTR UTRN COL12A1 MACF1 ELK3	3.07e-07	200	199	9	dccec522ab0d7fff62ad6273b02aa9022dbbb8eb
ToppCell	LPS_only-Endothelial-Endothelial-Activated_Alv_Cap\|LPS_only / Treatment groups by lineage, cell group, cell type	ERG EHD2 SYNE2 SMCHD1 MACF1 CTH ELK3 DISP1 MX1	3.07e-07	200	199	9	edb64556b3fefe3144f73b6efe23b9ffd34091d2
ToppCell	LPS_anti-TNF-Endothelial-Endothelial-Gen_Cap\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	ERG SPEF2 ITPRID2 PTK2 SYNE2 NKTR UTRN MACF1 ELK3	3.07e-07	200	199	9	a2b9d1cd291d17abddc3ee2e242121412c864b8b
ToppCell	10x5'-bone_marrow-Lymphocytic_T_CD4-T_CD4/CD8\|bone_marrow / Manually curated celltypes from each tissue	HIPK1 PTPRC PSME4 SYNE2 NKTR SMCHD1 ANKRD44 MACF1	5.27e-07	156	199	8	1545169694f686d28648a68b552c2ae606599d66
ToppCell	TCGA-Mesothelium-Primary_Tumor-Mesothelioma-Epitheliod-2\|TCGA-Mesothelium / Sample_Type by Project: Shred V9	ADCY3 RGL1 TRANK1 FGD4 EMB PKD1L3 HELQ MINDY1	6.39e-07	160	199	8	d288b0a315f6adc0be4bdc89fa67bf93679a743f
ToppCell	LPS-IL1RA+antiTNF\|World / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	MYO9A LRRK2 ETV1 TMEM132C PXDNL PLOD2 UTRN FAM13A	1.37e-06	177	199	8	b7fee75de7e96924af488a5baa2334711889ae7c
ToppCell	RSV-Healthy-0\|RSV / Virus stimulation, Condition and Cluster	CHN1 KAT2B PTPRC SYNE2 CPLANE1 UTRN GSTK1 MX1	1.55e-06	180	199	8	974044056e2f7e909cb11c6f6ca89e58bf95f7e5
ToppCell	RSV-Healthy-0\|Healthy / Virus stimulation, Condition and Cluster	CHN1 KAT2B PTPRC SYNE2 CPLANE1 UTRN GSTK1 MX1	1.55e-06	180	199	8	703a1d0f9536af94d56757eb01221878d7b7fe61
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	MYO9A LAMA1 LRRK2 CLSTN2 COL12A1 PPFIBP1 PALS2 RIMS2	1.62e-06	181	199	8	9d782ba5cf5a172cb4f447763fc50e5b13ef7dd9
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_3\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	MYO9A LAMA1 LRRK2 CLSTN2 COL12A1 PPFIBP1 PALS2 RIMS2	1.68e-06	182	199	8	eb138aa1dca9373f1586600f258df06dcf56d81f
ToppCell	CV-Moderate-7\|Moderate / Virus stimulation, Condition and Cluster	MYCBP2 PTPRC PDP2 UBR2 SMCHD1 ANKRD44 MACF1 PRKDC	1.90e-06	185	199	8	a6c9203ce6c2892a4a369c9bcfb85720f01cbb3f
ToppCell	renal_medulla_nuclei\|World / Celltypes from Cells and Nuclei per compartment and clinical group	MYO9A MYO10 ERC1 LAMA1 PTK2 PXDNL UTRN PDE7B	2.23e-06	189	199	8	830d9cd0dd706bce22eb2416f07b2c31c870a05a
ToppCell	CD8+_Memory_T_cell-CV-7\|CD8+_Memory_T_cell / cell class, Virus stimulation and cluster	MYCBP2 PTPRC NKTR UBR2 SMCHD1 ANKRD44 MACF1 PRKDC	2.41e-06	191	199	8	9454f642c3621370fa23640b631301346b300950
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	BNC2 LRRK2 CLSTN2 ZNF462 VCAM1 PPFIBP1 PALS2 ACSM2B	2.41e-06	191	199	8	1cb02007adb344f17ef73d58890f91298c7cf5a1
ToppCell	severe-low-quality_cells\|severe / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	SYNE2 NKTR UTRN SMCHD1 ANKRD44 TRIM33 MACF1 PABPC1L	2.61e-06	193	199	8	9337bc93e3904c7fc7c93c328518bcd6453b1e8c
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_1\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ZNF346 CCDC8 MYO7A MYO9A SPTA1 SYNE2 GJA10	2.82e-06	137	199	7	761cc0e2b4971e98f6d0691d4575b5cd208b602d
ToppCell	mild-low-quality_cells\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	BNC2 SYNE2 NKTR UTRN UBR2 SMCHD1 ANKRD44 MACF1	3.27e-06	199	199	8	f0b0097df0026496470a80d8cc9375ffd8389b00
ToppCell	LPS_IL1RA-Endothelial-Endothelial\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	ERG ITPRID2 PTK2 EHD2 SYNE2 MACF1 ELK3 DISP1	3.40e-06	200	199	8	72ea9882a8ed26fa1534aeb6ba0d1897dccc20c5
ToppCell	Tracheal-NucSeq-Stromal-Chondrocytic\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	BNC2 ERG PLOD2 PPP4R4 CSPG4 PDE4DIP CTH PALS2	3.40e-06	200	199	8	b5a54b9baf79aea01f76a161f0a39bbe87eb4945
ToppCell	mild-CD8+_Tem\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	TRANK1 PTPRC SYNE2 UTRN EMB SMCHD1 MACF1 MX1	3.40e-06	200	199	8	d8aec4904c9420b8f9d7508658ba1e36c66cdfcc
ToppCell	LPS_IL1RA-Endothelial\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	ERG ITPRID2 PTK2 EHD2 SYNE2 MACF1 ELK3 DISP1	3.40e-06	200	199	8	5c092b2ecc081b5d04476c56333c338cd89ab984
ToppCell	Tracheal-NucSeq-Stromal-Chondrocytic-Chondrocyte\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	BNC2 ERG PLOD2 PPP4R4 CSPG4 PDE4DIP CTH PALS2	3.40e-06	200	199	8	f5bd0b30e478dac09f68c46b0781f5f2e7e3c693
ToppCell	LPS_only-Endothelial\|LPS_only / Treatment groups by lineage, cell group, cell type	ERG ITPRID2 EHD2 SYNE2 MACF1 CTH ELK3 DISP1	3.40e-06	200	199	8	81e76508c9050d533853d5fd2f3097b27613d836
ToppCell	LPS_IL1RA_TNF-Endothelial-Endothelial-Activated_Alv_Cap\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	ERG WWC3 SYNE2 SMCHD1 CTH ELK3 DISP1 MX1	3.40e-06	200	199	8	89821a264e872ed53e08e9d3609d5cc5c314503e
ToppCell	LPS_anti-TNF-Endothelial-Endothelial-Alv_Cap\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	ERG MYCBPAP EHD2 SMCHD1 CTH ELK3 DISP1 KIF1C	3.40e-06	200	199	8	66f7e8ee63c828f17468e79a4b816346b33e8980
ToppCell	VE\|World / Condition, Cell_class and T cell subcluster	MYCBP2 TRANK1 PTPRC SYNE2 UTRN SMCHD1 MACF1 MX1	3.40e-06	200	199	8	8ae7cb81de3ffac5acdf3466d4b516d80cac95d3
ToppCell	Bronchial-NucSeq-Stromal-Chondrocytic\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	ERG CMYA5 PPP4R4 CSPG4 TRPV4 CTH PALS2 PDE7B	3.40e-06	200	199	8	b7b9441fa7ab0d43741a2ebd5ec1a48d537c6d47
ToppCell	COVID-19-COVID-19_Mild-Lymphocyte-T/NK-NK_activated\|COVID-19_Mild / Disease, condition lineage and cell class	KAT2B TRANK1 PTPRC SYNE2 UTRN MACF1 LGR6 MX1	3.40e-06	200	199	8	2281debd86e5d92e8fe0397aec9ef670800f7471
ToppCell	COVID-19\|World / Disease, condition lineage and cell class	MYCBP2 SYNE2 UTRN EMB SMCHD1 GRB2 MACF1 MX1	3.40e-06	200	199	8	7dec470c379cd89f05a0f37c8628b21f136e52f0
ToppCell	LPS_only-Endothelial-Endothelial\|LPS_only / Treatment groups by lineage, cell group, cell type	ERG ITPRID2 EHD2 SYNE2 MACF1 CTH ELK3 DISP1	3.40e-06	200	199	8	4bb609a284d4e6066f17470a1736076aa4a1f84c
ToppCell	Bronchial-NucSeq-Stromal-Chondrocytic-Chondrocyte\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	ERG CMYA5 PPP4R4 CSPG4 TRPV4 CTH PALS2 PDE7B	3.40e-06	200	199	8	7c673ad0ea503ebd196579684d25d5f9e6a41030
ToppCell	10x5'-blood-Lymphocytic_T_CD4-T_CD4/CD8\|blood / Manually curated celltypes from each tissue	PTPRC SYNE2 NKTR UTRN SMCHD1 ANKRD44 MACF1	8.51e-06	162	199	7	b4535bcb3f469bc139e73f1122f4070013e5a1de
ToppCell	TCGA-Ovary-Primary_Tumor-Ovarian_Carcinoma-Serous_Cystadenocarcinoma-5\|TCGA-Ovary / Sample_Type by Project: Shred V9	ERC1 HIPK1 GAS8 OBSCN GON4L CPLANE1 USP40	9.98e-06	166	199	7	32d2eaf8a5d03881bf74d680825af2d5110b082d
ToppCell	3'_v3-lymph-node_spleen-Lymphocytic_T_CD4-T_CD4/CD8\|lymph-node_spleen / Manually curated celltypes from each tissue	HIPK1 PTPRC SYNE2 NKTR UTRN SMCHD1 MACF1	1.21e-05	171	199	7	2e9a20f8980b78325c52065a9c14ab3656267c05
ToppCell	PND03-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	BNC2 SMYD1 RNF112 BNC1 SYNE2 PALS2 AHNAK2	1.31e-05	173	199	7	30d67738633493d47f06ae452424382f069b6c0a
ToppCell	PND03-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial-Mesothelial_mature\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	BNC2 SMYD1 RNF112 BNC1 SYNE2 PALS2 AHNAK2	1.35e-05	174	199	7	a9c6edf5c3fc119c24425f921c5566a8356c30fe
ToppCell	droplet-Heart-nan-3m\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYO9A RPS6KA3 CMYA5 PSME4 PPP1R10 IBTK MACF1	1.46e-05	176	199	7	749b47eac5436fa34e0d243ffbc6f1897f4e431e
ToppCell	droplet-Limb_Muscle-MUSCLE-30m\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ERG MYO10 RPS6KA3 SYNE2 UTRN SMCHD1 PPP1R10	1.57e-05	178	199	7	01dafd19de04eff459253eaa9a35debf8f3deedf
ToppCell	systemic_lupus_erythematosus-treated-Lymphocytic_T-T4_reg-female\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	CHN1 HNRNPA1 TTC19 PTPRC SYNE2 FAM13A GSTK1	1.57e-05	178	199	7	90dedb3cef9b01907b9f8eec64218d6d2072be1f
ToppCell	wk_15-18-Mesenchymal-Chondrocyte-ASPN+_chondrocyte\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	ADCY3 COL12A1 CCDC110 DNAH1 AVIL CSPG4 AHNAK2	1.57e-05	178	199	7	a55130670aa95a87b833dd3cd2de461d779e4c06
ToppCell	systemic_lupus_erythematosus-treated-Lymphocytic_T-T4_reg\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	CHN1 HNRNPA1 TTC19 PTPRC SYNE2 FAM13A GSTK1	1.57e-05	178	199	7	d6312286bf6cc5b107ccd7adb583d9667d4e1d21
ToppCell	COVID-19-T_cells-Tregs\|COVID-19 / group, cell type (main and fine annotations)	F5 KAT2B PTPRC SYNE2 EMB SMCHD1 ANKRD44	1.75e-05	181	199	7	534659cf754326c6a73c0daa30e9d610612a0292
ToppCell	10x5'-Liver-Lymphocytic_T_CD4-T_CD4/CD8\|Liver / Manually curated celltypes from each tissue	PTPRC SYNE2 NKTR SMCHD1 ANKRD44 PPP1R10 MACF1	1.75e-05	181	199	7	f2315414e714ac86211546a935660c4be6e85f1b
ToppCell	Somatosensory_Cortex_(S1)-Non-neuronal-Macroglial-Oligo-OPC\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	KCNH8 MYO10 ZNF462 TMEM132C KAT2B LIMD1 CSPG4	1.81e-05	182	199	7	8a8b08ac4bb3cba3541dbe234e088703842285b9
ToppCell	Somatosensory_Cortex_(S1)-Non-neuronal-Macroglial-Oligo-OPC-OPC_L1-6_MYT1\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	KCNH8 MYO10 ZNF462 TMEM132C KAT2B LIMD1 CSPG4	1.81e-05	182	199	7	e36766309c4d96a90d213ce37d3acef1029a3fdc
ToppCell	droplet-Trachea-3m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell-smooth_muscle_cell_of_trachea_l44-58\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	MYO7A ZNF354C TMEM132C FOXO6 VARS2 DNAH1 UNK	1.88e-05	183	199	7	dc9602bed3136db91faeffef177006246dc92743
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SPTA1 LAMA1 OBSCN TRANK1 COL12A1 DNAH10 DNAH1	1.94e-05	184	199	7	2cbed6462fea2622871bb7e49b0df3d984239281
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SPTA1 LAMA1 OBSCN TRANK1 COL12A1 DNAH10 DNAH1	1.94e-05	184	199	7	ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SPTA1 LAMA1 OBSCN TRANK1 COL12A1 DNAH10 DNAH1	1.94e-05	184	199	7	2b19a8c5f823e00812908b23e66bb4e563278aff
ToppCell	10x5'-Lung-Mast\|Lung / Manually curated celltypes from each tissue	ERG MYO10 SPTB ZNF462 ARHGEF6 PDE7B AHNAK2	2.16e-05	187	199	7	f8ac5ca5cbe9c6f3d8c0fffc20fe08ca1aea43c0
ToppCell	10x5'-Lung-Mast-Mast_cells\|Lung / Manually curated celltypes from each tissue	ERG MYO10 SPTB ZNF462 ARHGEF6 PDE7B AHNAK2	2.16e-05	187	199	7	da275d2c774b3e6a8ed77f777dd0676ecf2ddd2c
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Degenerative_Descending_Thin_Limb_Cell_Type_3\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	BNC2 MYO9A LAMA1 LRRK2 SYNE2 PALS2 RIMS2	2.16e-05	187	199	7	c31130fc2f9f882944b2ba366a034a03f051c4b9
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	BNC2 LRRK2 CLSTN2 ZNF462 PPFIBP1 PALS2 ACSM2B	2.16e-05	187	199	7	9d77ca45f7563bd6f2a0c1be5d99d93ad30983f7
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Endothelial-lymphatic_endothelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ERG RNF112 EHD2 BNC1 UTRN PPFIBP1 ELK3	2.16e-05	187	199	7	65d406122dffe18279f14a1ed35ba091730b97be
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	BNC2 MYO9A LAMA1 LRRK2 PPFIBP1 PALS2 RIMS2	2.16e-05	187	199	7	c41a2c81dd2ceef303f39f699032aa7d6ea67cf0
ToppCell	Fetal_29-31_weeks-Mesenchymal-myofibroblast_cell\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	ERG HPSE2 CLSTN2 CHN1 TMEM132C COL12A1 DISP1	2.16e-05	187	199	7	c104fbfef2d0bef64077ac721edf2379fd59d547
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell_of_renal_cortex-lymphatic_endothelial_cell_of_renal_cortex\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ERG RNF112 EHD2 BNC1 UTRN PPFIBP1 ELK3	2.16e-05	187	199	7	4c15c0ed41a55271fc793cb76fee97fa64190369
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell_of_renal_cortex\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ERG RNF112 EHD2 BNC1 UTRN PPFIBP1 ELK3	2.16e-05	187	199	7	5274f2b302bbf7fed30c480af4f35058d2cf61e0
ToppCell	VE-Treg-CD4_Treg\|VE / Condition, Cell_class and T cell subcluster	CPNE2 CHN1 F5 SYNE2 SMCHD1 FAM13A MX1	2.23e-05	188	199	7	fa88ceb336e30de3585e62608527a0d44df74190
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	BNC2 MYO9A LAMA1 LRRK2 SYNE2 PALS2 RIMS2	2.23e-05	188	199	7	af740fa78542438fdff627ea1f74f4eee43316be
ToppCell	VE-Treg\|VE / Condition, Cell_class and T cell subcluster	CPNE2 CHN1 F5 SYNE2 SMCHD1 FAM13A MX1	2.23e-05	188	199	7	ef048517dfe2fc995d13eb1f08106a487354a4cc
ToppCell	systemic_lupus_erythematosus-flare-Lymphocytic_T-T4_reg\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	CHN1 HNRNPA1 TTC19 PTPRC SYNE2 SMCHD1 GSTK1	2.23e-05	188	199	7	e5c480b9a030536578f1cc91fb61738f752525b3
ToppCell	COVID-19-Heart-EC_(POSTN)\|COVID-19 / Disease (COVID-19 only), tissue and cell type	BNC2 ERG CHN1 F5 TMEM132C PWWP3B PDE7B	2.31e-05	189	199	7	7346c1112e2e155dbd71b6dbc80e680fd262a691
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	BNC2 LRRK2 CLSTN2 VCAM1 PPFIBP1 PALS2 ACSM2B	2.31e-05	189	199	7	3b48b0d220cc24d5170713d61fa91f5bb6c21841
ToppCell	tumor_Lung-Fibroblasts-Pericytes\|Fibroblasts / Location, Cell class and cell subclass	CHN1 ADCY3 PTK2 EHD2 PXDNL SYNE2 CSPG4	2.31e-05	189	199	7	9c407b17d7945e81e1ae6c18452f5d20fb09d563
ToppCell	droplet-Lung-LUNG-1m-Mesenchymal-bronchial_smooth_muscle_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	BNC2 ETV1 CLSTN2 CMYA5 ZNF462 PDP2 LGR6	2.31e-05	189	199	7	4dc32b463546bbe7250dddd281b92ad17ec22da1
ToppCell	droplet-Lung-LUNG-1m-Mesenchymal-Airway_Smooth_Muscle\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	BNC2 ETV1 CLSTN2 CMYA5 ZNF462 PDP2 LGR6	2.31e-05	189	199	7	0d06bf0d7191d13a1c4f30a7881e7ea1093bfd6f
ToppCell	BAL-Control-Lymphocyte-B-B_cell\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	LRRK2 ZNF829 SYNE2 EMB PABPC1L PALS2 PDE7B	2.39e-05	190	199	7	da7341a8a423e5fe4d8e733d8e50c10a3318ac1c
ToppCell	5'-Parenchyma_lung-Immune_Lymphocytic-Lymphocytic_T/NK-CD8-positive,_alpha-beta_T_cell-CD8_T_cells-CD8_T_cells_L.1.1.4.0\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	PTPRC SYNE2 UTRN SMCHD1 ANKRD44 MACF1 LGR6	2.39e-05	190	199	7	d153a0bdedcd6865e6ee19575234a78b5d859ff1
ToppCell	BAL-Control-Lymphocyte-B-B_cell-B_cell\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	LRRK2 ZNF829 SYNE2 EMB PABPC1L PALS2 PDE7B	2.39e-05	190	199	7	42312f7d79fe889397d32910b625793e2535cc26
ToppCell	BAL-Control-Lymphocyte-B-B_cell-B_cell-B_activate-7\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	LRRK2 ZNF829 SYNE2 EMB PABPC1L PALS2 PDE7B	2.39e-05	190	199	7	682418a7a2096743112eae3790d40e7e600612c0
ToppCell	systemic_lupus_erythematosus-flare-Lymphocytic_T-T4_reg-female\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	CHN1 TTC19 PTPRC SYNE2 SMCHD1 FAM13A GSTK1	2.47e-05	191	199	7	c5e22df4a8741b8096cdd1618271fd48d6265846
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Myocytic_interstitial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	ERG HPSE2 ADCY3 UTRN COL12A1 CSPG4 LGR6	2.47e-05	191	199	7	04c4d454b57e29a8d1dcdeb4678ce71bdc29b77b
ToppCell	COVID-19-Heart-EC_(POSTN)\|Heart / Disease (COVID-19 only), tissue and cell type	BNC2 ERG CHN1 TMEM132C VCAM1 PWWP3B PDE7B	2.55e-05	192	199	7	c0c34785a7bdf461722029b322e9184e3d9b3c26
ToppCell	10x5'-lymph-node_spleen-Lymphocytic_T_CD4-T_CD4/CD8\|lymph-node_spleen / Manually curated celltypes from each tissue	HIPK1 PTPRC SYNE2 NKTR SMCHD1 ANKRD44 MACF1	2.55e-05	192	199	7	47646d7e4990be85072987f92bf18d52f8da752e
ToppCell	renal_cortex_nuclei\|World / Celltypes from Cells and Nuclei per compartment and clinical group	BNC2 ERC1 PTK2 FGD4 SYNE2 MACF1 ACSM2B	2.55e-05	192	199	7	e8cc4d08fcfceeab75a02558817e4ccd7dbafe3a
ToppCell	TCGA-Prostate-Primary_Tumor-Prostate_Adenocarcinoma-Acinar_Adenocarcinoma-6\|TCGA-Prostate / Sample_Type by Project: Shred V9	TASOR2 USP32 CPLANE1 UTRN THOC2 TRIM33 PRKDC	2.64e-05	193	199	7	abd71b2cf667ef2b1c4d88acd0c1dd19a12ff659
ToppCell	10x_3'_v3-thymus_(10x_3'_v3)-lymphocytic-T_lymphocytic-CD8-positive,_alpha-beta_T_cell\|thymus_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	PTPRC SYNE2 NKTR UTRN EMB PPP1R10 MACF1	2.64e-05	193	199	7	a594f89a18273797506287d9e22f72abe53e4920
ToppCell	wk_08-11-Hematologic-Meg-ery-Definitive_erythroblast\|wk_08-11 / Celltypes from embryonic and fetal-stage human lung	HIPK1 SPTA1 SPTB UGGT1 ULK1 UBR2 PKD1L3	2.64e-05	193	199	7	be75abfdf5301cf33df8ee9ed92504d44fdf19a6
ToppCell	RV-10._Endothelium_II\|World / Chamber and Cluster_Paper	ERG TMEM132C SYNE2 VCAM1 PPFIBP1 PWWP3B PDE7B	2.64e-05	193	199	7	2531266bc57339d4e2b22a88817008e32b8c1598
ToppCell	10x_3'_v2v3-Non-neoplastic-Lymphoid-CD4/CD8-CD8_NK_sig-C\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	ERC1 LIN54 ZNF829 PTPRC PDP2 NKTR AHNAK2	2.73e-05	194	199	7	6be74e4ba631b0c46cef2c580553f4c1ed29579e
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ERG HPSE2 ADCY3 UTRN COL12A1 CSPG4 LGR6	2.73e-05	194	199	7	ebb038f94f49f5c655578d1b018676e10c6b7e3c
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	ERG HPSE2 ADCY3 UTRN COL12A1 CSPG4 LGR6	2.91e-05	196	199	7	b8759e6231e0254797d6c30930407b79440c57bb
ToppCell	distal-Endothelial-Lymphatic-1\|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	MYO7A SPTA1 BNC1 ZSCAN4 PPFIBP1 ELK3 PDE7B	2.91e-05	196	199	7	b0f23dc802a2c2a56a08d398a464ea78b58ade4c
ToppCell	COVID_non-vent-Lymphocytic-T_cell-CD8+_Memory_T_cell\|COVID_non-vent / Disease condition, Lineage, Cell class and subclass	TRANK1 PTPRC SYNE2 NKTR UTRN MACF1 LGR6	3.01e-05	197	199	7	836061acd7f0d5de89b16f52ec679bdf09eac9db
ToppCell	severe-low-quality_cells\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	PTPRC SYNE2 NKTR UTRN SMCHD1 ANKRD44 MACF1	3.01e-05	197	199	7	57ebd552f10d6278623b52a3d484d4b91ae1d028
ToppCell	Control-Control-Lymphocyte-T/NK-CD4+_T_activated\|Control / Disease, condition lineage and cell class	EPC2 TRANK1 SYNE2 SMCHD1 MACF1 PABPC1L MX1	3.11e-05	198	199	7	ee71543559836fd59adc0da877b2ca538cba60cb
Drug	C.I. 337	ERG ERC1 PTK2 PIK3R4 VCAM1 EMB AVIL	3.82e-07	54	195	7	CID006331826
Drug	chlorpromazine hydrochloride; Down 200; 1uM; MCF7; HT_HG-U133A_EA	SPATA7 STAM2 MYO9A ITPRID2 COPS2 PSME4 AKT1 NKTR HSPA4 PLEKHB2 RRN3	1.24e-06	199	195	11	1055_DN
Drug	plakin	SPTA1 SPTB GAS2 COPS2 SYNE2 UTRN MACF1	6.71e-06	82	195	7	CID000018752
Drug	Norfloxacin [70458-96-7]; Down 200; 12.6uM; PC3; HT_HG-U133A	RABEP2 GON4L ADCY3 BNC1 UTRN LIMD1 PPFIBP1 NPTXR MX1 KIF1C	7.76e-06	196	195	10	2090_DN
Drug	S 131	CHN1 KAT2B CTH MX1	8.76e-06	16	195	4	CID005744397
Disease	amygdala volume change measurement	PKD1L1 EMB SPATA31C2	1.36e-04	16	189	3	EFO_0021490
Disease	Coffin-Lowry syndrome (implicated_via_orthology)	RPS6KA3 RPS6KA6	2.43e-04	4	189	2	DOID:3783 (implicated_via_orthology)
Disease	Hereditary elliptocytosis	SPTA1 SPTB	2.43e-04	4	189	2	cv:C0013902
Disease	Adenocarcinoma of lung (disorder)	HNRNPA1 RPS6KA6 ALDH18A1 AKT1 ULK1 TRIM33 PRKDC	3.82e-04	206	189	7	C0152013
Disease	hereditary spherocytosis (is_implicated_in)	SPTA1 SPTB	4.03e-04	5	189	2	DOID:12971 (is_implicated_in)
Disease	Hereditary spherocytosis	SPTA1 SPTB	4.03e-04	5	189	2	cv:C0037889
Disease	JOUBERT SYNDROME 17	KIAA0586 CPLANE1	4.03e-04	5	189	2	C3553264
Disease	Anemia, hereditary spherocytic hemolytic	SPTA1 SPTB	4.03e-04	5	189	2	C0221409
Disease	Parkinson's disease (implicated_via_orthology)	HIPK1 AKT1 FOXO6 HIPK4 RRN3 VPS35	5.41e-04	157	189	6	DOID:14330 (implicated_via_orthology)
Disease	Elliptocytosis, Hereditary	SPTA1 SPTB	6.02e-04	6	189	2	C0013902
Disease	Ciliopathies	SPATA7 MYO7A CPLANE1 CEP164 LEFTY2	7.27e-04	110	189	5	C4277690
Disease	Ovarian Mucinous Adenocarcinoma	LRRK2 MELK ULK1	1.02e-03	31	189	3	C1335167
Disease	Hereditary spherocytosis	SPTA1 SPTB	1.11e-03	8	189	2	C0037889
Disease	Ewings sarcoma	ERG ETV1	1.11e-03	8	189	2	C0553580
Disease	Situs ambiguous	PKD1L1 LEFTY2	1.43e-03	9	189	2	C1167664
Disease	Kartagener Syndrome	SPEF2 GAS8 DNAH1	1.46e-03	35	189	3	C0022521
Disease	Ciliary Dyskinesia, Primary, 1, With Or Without Situs Inversus	SPEF2 GAS8 DNAH1	1.46e-03	35	189	3	C4551906
Disease	Polynesian Bronchiectasis	SPEF2 GAS8 DNAH1	1.46e-03	35	189	3	C4317124
Disease	Parkinson's disease (is_implicated_in)	LRRK2 AKT1 DNAJC13 VPS35	1.46e-03	76	189	4	DOID:14330 (is_implicated_in)
Disease	Facies	DNMT3A CHD8	1.78e-03	10	189	2	C0282631
Disease	macrovascular complications of diabetes	F5 PDE4DIP	1.78e-03	10	189	2	EFO_0010977
Disease	osteonecrosis (is_implicated_in)	F5 TRPV4	1.78e-03	10	189	2	DOID:10159 (is_implicated_in)
Disease	Hodgkins lymphoma	TM7SF3 CLSTN2 CPLANE1 KIF16B	1.93e-03	82	189	4	EFO_0000183
Disease	urate measurement	BNC2 MYO9A GON4L GJA10 DNAJC13 GRB2 VARS2 DNAH1 ZNF675 AP4E1 CACNA2D4 FAM13A CSPG4 PALS2	1.97e-03	895	189	14	EFO_0004531
Disease	Profound Mental Retardation	LAMA1 GON4L DNMT3A CHD8 AP4E1	2.06e-03	139	189	5	C0020796
Disease	Mental Retardation, Psychosocial	LAMA1 GON4L DNMT3A CHD8 AP4E1	2.06e-03	139	189	5	C0025363
Disease	Mental deficiency	LAMA1 GON4L DNMT3A CHD8 AP4E1	2.06e-03	139	189	5	C0917816
Disease	hair colour measurement	BNC2 GAS8 ETV1 BNC1 SYNE2 PLXNA1 FOXO6 EMB PKD1L3 FAM13A PALS2	2.15e-03	615	189	11	EFO_0007822
Disease	cocaine use	HSPA4 DNMT3A	2.16e-03	11	189	2	C3496069
Disease	triglycerides:total lipids ratio, high density lipoprotein cholesterol measurement	GCK SYNE2 DNAH10 DNAH1 FAM13A RRN3	2.19e-03	206	189	6	EFO_0004612, EFO_0020947
Disease	forced expiratory volume, response to bronchodilator	SPEF2 NPSR1 ETV1 CLSTN2 CHN1 NUP205 FGD4 PPP4R4 FAM13A	2.40e-03	445	189	9	EFO_0004314, GO_0097366
Disease	FEV/FEC ratio	BNC2 TRIT1 WWC3 ERC1 SPEF2 KIAA0586 ETV1 COPS2 ADCY3 ZNF354C PTK2 SYNE2 ASCC2 HSPA4 TRIM33 FAM13A CSPG4	2.43e-03	1228	189	17	EFO_0004713
Disease	neurodegenerative disease (implicated_via_orthology)	VAPB LRRK2 HNRNPA1L3 HNRNPA1 UBR2	2.47e-03	145	189	5	DOID:1289 (implicated_via_orthology)
Disease	aspartate aminotransferase measurement, serum alanine aminotransferase measurement, low density lipoprotein triglyceride measurement, body fat percentage, high density lipoprotein cholesterol measurement, sex hormone-binding globulin measurement	BNC2 ADCY3 RPTOR DNAH10 SMCHD1 ANKRD44 FAM13A MACF1	2.50e-03	364	189	8	EFO_0004612, EFO_0004696, EFO_0004735, EFO_0004736, EFO_0007800, EFO_0009946
Disease	calcium measurement	HPSE2 COPS2 SYNE2 DNMT3A CHD8 PPP4R4 USP40 PTRH2 MACF1 PDE7B MINDY1	2.53e-03	628	189	11	EFO_0004838
Disease	spleen volume	SPTA1 ASCC2 KIF1C	2.64e-03	43	189	3	EFO_0600047
Disease	Muscular Dystrophy, Facioscapulohumeral	HSPA4 SMCHD1	3.04e-03	13	189	2	C0238288
Disease	heart rate variability measurement, response to antipsychotic drug	UGGT1 RGL1 COL12A1	3.21e-03	46	189	3	EFO_0008003, GO_0097332
Disease	triglyceride measurement, very low density lipoprotein cholesterol measurement	GCK SYNE2 DNAH10 DNAH1 RRN3 MACF1	3.31e-03	224	189	6	EFO_0004530, EFO_0008317
Disease	apolipoprotein A 1 measurement	CPNE2 LIN54 NUP205 TRANK1 PDP2 AKT1 DNAH10 PKD1L3 CEP164 FAM13A MACF1 MINDY1 LRRFIP1	3.36e-03	848	189	13	EFO_0004614
Disease	Paroxysmal atrial fibrillation	PTK2 MEX3C ZNF462 SYNE2 DNAH10	3.39e-03	156	189	5	C0235480
Disease	familial atrial fibrillation	PTK2 MEX3C ZNF462 SYNE2 DNAH10	3.39e-03	156	189	5	C3468561
Disease	Persistent atrial fibrillation	PTK2 MEX3C ZNF462 SYNE2 DNAH10	3.39e-03	156	189	5	C2585653
Disease	Primary Ciliary Dyskinesia	SPEF2 GAS8 DNAH1	3.41e-03	47	189	3	C4551720
Disease	age at menopause	ZNF346 PIWIL1 TASOR2 BNC1 HELQ DNAJC11 PRKDC	3.45e-03	302	189	7	EFO_0004704
Disease	Atrial Fibrillation	PTK2 MEX3C ZNF462 SYNE2 DNAH10	3.77e-03	160	189	5	C0004238
Disease	Malignant neoplasm of breast	KDM3A RPS6KA3 OBSCN PIK3R4 RGL1 PTPRC SYNE2 AKT1 DNMT3A KIF16B HELQ MACF1 ELK3 LGR6 LRRFIP1	4.00e-03	1074	189	15	C0006142
Disease	Situs ambiguus	PKD1L1 LEFTY2	4.06e-03	15	189	2	C0266642
Disease	B-cell acute lymphoblastic leukemia	ERG ELK3	4.06e-03	15	189	2	EFO_0000094
Disease	red blood cell density measurement	TRIT1 ERG MYO9A SPTA1 LIN54 NUP205 ZNF462 KAT2B PTPRC DNMT3A DNAH10 TRIM33 FAM13A	4.57e-03	880	189	13	EFO_0007978
Disease	Polyposis, Adenomatous Intestinal	F5 AKT1	4.62e-03	16	189	2	C2713442
Disease	Familial Intestinal Polyposis	F5 AKT1	4.62e-03	16	189	2	C2713443
Disease	obesity	RABEP2 GAS8 CMYA5 ADCY3 RPTOR LRRFIP1	4.72e-03	241	189	6	EFO_0001073
Disease	Adenomatous Polyposis Coli	F5 AKT1	5.21e-03	17	189	2	C0032580
Disease	sexual dimorphism measurement	ZNF346 ADCY3 ZNF462 TRANK1 DNMT3A FOXO6 DNAH10 RASGRF1 SPATA31C2 GRB2 PKD1L3 CEP164 RRN3 AVIL MACF1	5.22e-03	1106	189	15	EFO_0021796
Disease	aspartate aminotransferase measurement	WWC3 MYO7A OBSCN ETV1 HPSE2 RGL1 PTPRC DNAJC13 KIF16B GRB2 PDPK2P FAM13A PDE7B	5.70e-03	904	189	13	EFO_0004736
Disease	Glioblastoma Multiforme	RPS6KA3 PTK2 TRIM33 BRD2	5.73e-03	111	189	4	C1621958

Protein segments in the cluster

Peptide	Gene	Start	Entry
EEQEKKPLRQMIDSH	ZNF354C	136	Q86Y25
AEEMEVSLAKPKHRV	AKT1	131	P31749
HDDKPNIVLIMVDDL	ARSF	26	P54793
IMDRISTEHDPVLKQ	EPC2	461	Q52LR7
LLHTKPEVAAQERMV	AVIL	376	O75366
MEEPNHLDVDLETRI	CHD8	2301	Q9HCK8
DREKMSVRDHDPEVL	LINC01590	36	Q5TEZ4
EETRHAVVQASKLPM	CPNE2	451	Q96FN4
LLQELERHMEDTHPD	ARHGEF6	386	Q15052
NIMDDPFIREHIEEL	COPS2	336	P61201
HVQPTLDLMEAELRK	CSPG4	451	Q6UVK1
NPVMIDAKEVSAAHR	DNMT3A	776	Q9Y6K1
KVLMNSERPDENHSE	BNC2	751	Q6ZN30
VASAPEVVDMQKRLH	ASCC2	106	Q9H1I8
KSHLRAQMENPDLDL	GJA10	111	Q969M2
PKLLEALDEMLTHDI	EHD2	376	Q9NZN4
DDVDKALQNSPRLMH	ERG	206	P11308
HAVEKINPDEREEMK	GCLM	76	P48507
EKRHNLSSDEDMPLQ	BNC1	556	Q01954
PAIMTHASVLKNDRD	CTH	351	P32929
KHMLDVENSPLIADD	AADACL4	316	Q5VUY2
DPKSEVLEEMLHNLD	CLSTN2	681	Q9H4D0
THMLETDEENTKPRV	DMXL1	1456	Q9Y485
SLQRSIEEHLPKMAE	DISP1	1376	Q96F81
LHENVELMKSLLPVD	AP4E1	596	Q9UPM8
EKSHLVPLMDARINA	KIF16B	1106	Q96L93
EEVDAAMNARPHKVD	HNRNPA1L3	21	A0A2R8Y4L2
PEMSDRIQHLEREIT	ERC1	731	Q8IUD2
HEDSEKLREIVLPME	RABEP2	146	Q9H5N1
RAMLKHNLDSDPAEE	RGL1	681	Q9NZL6
LHEKLNLPVENMDVT	PARPBP	71	Q9NWS1
DLMKLDHEEEPQLSE	GDAP1L1	191	Q96MZ0
RLETHEEASVKMLPT	GCK	46	P35557
HMVPLVEEINRLADE	INTS15	321	Q96N11
RDDMIHQLPLLTEKQ	NUP205	291	Q92621
VELDLNQAHMEETPK	MELK	506	Q14680
HVMLSQKPAVRDVDL	FHIP1B	431	Q8N612
SLEEERPALMDDRKH	PATL1	546	Q86TB9
HQVMVLDSEALRIPK	DNAJC11	536	Q9NVH1
VLHKRLSQVDPEMAA	TRIT1	161	Q9H3H1
PERKTLMHLADAAEV	LIN54	636	Q6MZP7
SLVEVHKSEENEEPM	HSPA4	496	P34932
ALTQRLEREMDAHPK	LIMD1	451	Q9UGP4
MTDSHVLEEAKKPRV	KAT2B	431	Q92831
RTERHEMQILSKPEF	NPSR1	356	Q6W5P4
PDREALAEHADLKSM	HIPK4	306	Q8NE63
AEAQHQKRDAMELPD	PPFIBP1	876	Q86W92
DLDELQLEMEDSKPH	LGR6	526	Q9HBX8
LIHADLKPENIMLVD	HIPK1	311	Q86Z02
SALDLVMKDRPTHVV	IBTK	121	Q9P2D0
KMERDILVEVNHPFI	RPS6KA3	116	P51812
DKLHVEMELSPDSQI	KIAA1109	721	Q2LD37
IEDHPVLKEMEVQAN	PLXNA1	1336	Q9UIW2
ESRLLAHLPKEMTQD	PDE7B	256	Q9NP56
INPEMKDRRHEESIL	FAM205C	266	A6NFA0
RPLLKTDMERHINEE	ETV1	431	P50549
SPLELEQLDQHHEMK	FGD4	186	Q96M96
MAAKLRAHQVDVDPD	FOXO6	1	A8MYZ6
PSRDEIEALIHRQEM	MYO10	1686	Q9HD67
MVIHAPKEEEIETLN	NIPA2	126	Q8N8Q9
LRMERVIPLAQDHED	KIF1C	866	O43896
PQKEVITSDELMAHL	MINDY1	156	Q8N5J2
TSHKILVSEDMDEPR	LRP5L	66	A4QPB2
MKRHETSLPVQLEAL	LRRK2	491	Q5S007
DDLKIDLMPHDLITQ	TUBGCP2	571	Q9BSJ2
KMERDILVEVNHPFI	RPS6KA6	121	Q9UK32
PEEIRMLIHKTEDVN	ANKRD44	21	Q8N8A2
HRDLKPENILLNEDM	PDPK2P	176	Q6A1A2
LMLESPESLHAKIDE	PABPC1L	581	Q4VXU2
IAQHPDVMLELQREK	HPSE2	166	Q8WWQ2
ASIPELLEHLQEMRE	FAM13A	946	O94988
PRAKAEEMLSKQRHD	GRB2	66	P62993
TPEEEQELEKRVMEH	ITPRID2	776	P28290
HEEMPEAKNVIAVLE	C17orf75	371	Q9HAS0
HEPMELLINDKVAQL	NPTXR	356	O95502
HRDLKPENILLDDNM	PHKG2	151	P15735
EEMRQLRESIAEHKP	MACF1	5821	Q9UPN3
MLATLEPEQRAEIIH	ALDH18A1	376	P54886
VPTDDIHMKQVDLEN	PLOD2	606	O00469
SNILMVHPAREDIKI	OBSCN	6591	Q5VST9
EPLMEHRVLEEEAAR	OBSCN	6916	Q5VST9
MPDLSHLTEEERKII	RIMS2	26	Q9UQ26
KREIQMPHESVVEQE	NT5DC4	386	Q86YG4
IAAPELETLRAMHKA	PALS2	456	Q9NZW5
KREHPESEDRTIIME	PDP2	321	Q9P2J9
PVDKDMELSHLRSRQ	PXDNL	1326	A1KZ92
EDLESMHPLLEEAAK	DNAH1	2851	Q9P2D7
ADQLPHVERKMLQDD	FCAMR	501	Q8WWV6
EKEAMSTIEPHRQVA	KDM3A	636	Q9Y4C1
RKEELNEMISHEQLP	BMP10	266	O95393
RVPEADSQLTEKMTH	CPLANE1	786	Q9H799
KNLPEDAIHTMIENL	COL12A1	951	Q99715
KNHDMVVVSPILERD	UPB1	156	Q9UBR1
DIDPDHRKLSQLEAM	CACNA2D4	691	Q7Z3S7
EKSEAMLAEAHPEIR	CMYA5	2596	Q8N3K9
MLAEAHPEIREAKAV	CMYA5	2601	Q8N3K9
NLVLEKSSRDMPDHS	CMYA5	2656	Q8N3K9
VNLEHPEMLEKASRE	GSTK1	106	Q9Y2Q3
IEHDKREMIFEVLAP	RAP1GDS1	236	P52306
KASLPSIQEELRHMA	GON4L	921	Q3T8J9
EEVRHLKTKPSDEEM	DBI	11	P07108
ENLMLSILPKHVADE	ADCY3	276	O60266
SSDLVPEKDADRMHV	DNAJC13	666	O75165
PEKDADRMHVRDNVK	DNAJC13	671	O75165
LKMDPHAVEISRESL	ELK3	91	P41970
ADMEKLVIPAHVRAQ	LEFTY2	46	O00292
RDPEVLREHMTQLKE	MANEAL	166	Q5VSG8
RTKEPIQMDAEHREV	HAUS6	606	Q7Z4H7
IQMDAEHREVLPESL	HAUS6	611	Q7Z4H7
EHSSMPVEKNITLER	EMB	66	Q6PCB8
KMDPDHLVALVTEVI	HELQ	561	Q8TDG4
SAKIMDPDEQLETLH	CHN1	366	P15882
TLEDVARIMEKSTPH	CCDC8	51	Q9H0W5
HFKDDVEVVMRDPIL	DNAH10	2716	Q8IVF4
LETPKLEEAEMVENH	PKD1L1	2771	Q8TDX9
EMSEHPSQTVRKALD	LRRFIP1	751	Q32MZ4
KMTVNNLHPRVTEED	POLDIP3	281	Q9BY77
NVMKDLAVHTRLTPE	PIWIL1	401	Q96J94
ASRHEANLLPMKEDL	GAS2	26	O43903
AAIHRSMANPEELDK	FOXN4	291	Q96NZ1
ERLDQMVHPVAERLD	RRN3	301	Q9NYV6
LDKAASHLRQLMDEP	VARS2	1041	Q5ST30
DTHLVFRPLMEKVEV	UTP4	306	Q969X6
HIEKIMAFREEIAPI	UTRN	2731	P46939
EIHQRLMEEEKENQP	SPEF2	1271	Q9C093
LASLENHVKIEPADM	TRIM33	831	Q9UPN9
RAKLHIDEMDSVPTV	VCAM1	196	P19320
DDQTRQNIEDKVHMP	PLEKHB2	36	Q96CS7
RMISKPADSQDVHEL	SMCHD1	251	A6NHR9
IELTHDPVANVRMKL	PPP4R4	611	Q6NUP7
RENSRKPNLEKHEEM	SPATA31C2	956	B4DYI2
MKLEEPHVATLQDSR	TMEM132C	616	Q8N3T6
EEEKRHLQEMANSLP	SYNE2	1481	Q8WXH0
TRKMHDRLEPEDEES	F5	706	P12259
VKHTQPEDGVEMDTR	LILRB1	536	Q8NHL6
PDINIVLKQDMATEH	NKTR	1156	P30414
KLHNEDAREPMAVTS	PWWP3B	516	Q5H9M0
PASTHREIEMAQKLL	PTK2	976	Q05397
ADLMTLSHREPKELD	LAMA1	236	P25391
MPENVDRAREEIEMH	MEX3C	376	Q5U5Q3
HPITKDLEAMRVQTE	SMYD1	431	Q8NB12
KRHTEPVEDILEMSL	PKD1L3	376	Q7Z443
PLLVAHMEKLSQSEE	MYCBP2	1636	O75592
EDSVIVRTMKPHAEL	WIZ	96	O95785
LRPSELQEHMEQELE	RNF220	231	Q5VTB9
RDKVHPMILAQEEDD	METTL22	141	Q9BUU2
VMHDPELLTQERKAA	RASGRF1	986	Q13972
VMKIPEEHDLESQIR	RPTOR	971	Q8N122
MKELPEQLQEHAIED	SAFB	171	Q15424
PDHDVVAMARKLQDV	BRD2	431	P25440
DKDEVAPQSAIHMDL	AHNAK2	4991	Q8IVF2
APKLDHQRMDTIQED	ADAM17	751	P78536
MSPEKQHREEDEVDS	CCDC110	1	Q8TBZ0
SEVENALMKHPAVVE	ACSM2B	476	Q68CK6
DASQELEISEHMKEP	CEP164	381	Q9UPV0
LEISEHMKEPQLSDS	CEP164	386	Q9UPV0
KEHDLAMINQLLDDP	CNK3/IPCEF1	831	G9CGD6
TQMIHREPDKRLEAE	PIK3R4	291	Q99570
PDEETLIALLAHAKM	PTRH2	121	Q9Y3E5
SIMKDEPEEAELILH	TTC19	106	Q6DKK2
KQLVARPDVVEMHDV	SF3B2	466	Q13435
EQPLEEERMHVGKNT	TTC30B	631	Q8N4P2
RPDLHTKEQILDMLV	ZSCAN5DP	71	P0CG00
IIEALANPEKERMKH	THOC2	616	Q8NI27
TSPDEMAAQLHDLRK	RNF112	446	Q9ULX5
MKELNEHADCVLPID	TUBE1	196	Q9UJT0
ADVEKLADELHMPSL	TIPRL	31	O75663
ERMKCFSEENHEPLR	VPS35	636	Q96QK1
DEIQPDLRELMETMH	VPS28	151	Q9UK41
VMVLPDENHREDALM	MYCBPAP	731	Q8TBZ2
EIKDDALQHSSPRAM	SPATA7	331	Q9P0W8
PMIDEKLEEIDRKHS	STAM2	331	O75886
MPDTLEDLEVVQHRF	SPTB	876	P11277
LMDSHPEQKEDIGQR	SPTB	1021	P11277
ESHPDATEDLQRQKM	SPTA1	1251	P02549
LKPLMDVDEEIQNHV	PSME4	1541	Q14997
PEEEERMHDELLQAV	ZNF829	16	Q3KNS6
QRDPTVHDDVLELEM	PRKDC	2071	P78527
EDMPLRDVIVHLTKQ	ZSCAN4	146	Q8NAM6
LEQEKEPLTVKRHEM	ZNF675	56	Q8TD23
LMDHLLSVPETVEKE	TOPAZ1	391	Q8N9V7
VEALHQNREMIDPDK	ZNF346	171	Q9UL40
EQPLEEERMHVGKNT	TTC30A	631	Q86WT1
QPEMHSKEQILELLV	ZKSCAN3	76	Q9BRR0
VSREEIHPKEIMENS	ZNF462	2446	Q96JM2
RVLHDEILNKPMETL	SLC35A3	71	Q9Y2D2
MAKVEQVLSLEPQHE	VAPB	1	O95292
DLPDNVEEVKLLLHM	TASOR2	781	Q5VWN6
LAPNRDDENMDKTHL	TRANK1	2346	O15050
EEVDAAMNARPHKVD	HNRNPA1	66	P09651
MAHSELVKSLPEDEN	UBR2	791	Q8IWV8
ASHAMIEKILSEEPR	UNK	191	Q9C0B0
TILRELEVQHPAAKM	CCT8	71	P50990
TARRLSHDNMEEKVP	PPP1R10	446	Q96QC0
RDDEKQLMNVEPIHA	PTPRC	621	P08575
QSEEEIDHPLMILKA	USP40	336	Q9NVE5
AIQAHMDQDEPLEVK	ZSCAN12	6	O43309
QHKEKMPEEEERLGR	WDR87	1786	Q6ZQQ6
SKIENRHEMLAVEPI	TRPV4	441	Q9HBA0
PEETLMEQEHTEILR	ULK1	831	O75385
KDNRTDDIPELHMDL	USP32	301	Q8NFA0
MDHINKLTQIEDPRE	WWC3	1	Q9ULE0
LDPDELETITMHKIL	UGGT1	646	Q9NYU2
LHPRAIVMSVAKDEE	KIAA0586	1156	Q9BVV6
LPENDLTEEMLLKHL	TM7SF3	201	Q9NS93
LAPEDMSKEQVEEHV	GAS8	21	O95995
PDELRSDITMHLNKE	KCNH8	531	Q96L42
QIKALEEPAVDMLHT	MX1	461	P20591
SMLEDRPTSNLEKLH	MYO7A	1141	Q13402
VKDFREKNTDHMRPD	MYO9A	661	B2RTY4
EKNTDHMRPDIVALL	MYO9A	666	B2RTY4
KQQLLHLLEEPTSME	PDE4DIP	196	Q5VU43