Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyBiologicalProcessmigracytosis

TSPAN4 TSPAN9

1.97e-06862GO:0140495
GeneOntologyBiologicalProcessmitocytosis

TSPAN4 TSPAN9

1.97e-06862GO:0160040
GeneOntologyBiologicalProcessmitochondrion distribution

TSPAN4 TSPAN9

2.47e-052762GO:0048311
GeneOntologyBiologicalProcessestablishment of mitochondrion localization

TSPAN4 TSPAN9

5.20e-053962GO:0051654
GeneOntologyBiologicalProcessmitochondrion localization

TSPAN4 TSPAN9

1.37e-046362GO:0051646
GeneOntologyBiologicalProcessregulation of mitochondrial membrane potential

TSPAN4 TSPAN9

3.45e-0410062GO:0051881
GeneOntologyCellularComponentmigrasome

TSPAN4 TSPAN9

2.47e-06962GO:0140494
GeneOntologyCellularComponentfocal adhesion

TSPAN4 TSPAN9

6.02e-0343162GO:0005925
GeneOntologyCellularComponentcell-substrate junction

TSPAN4 TSPAN9

6.35e-0344362GO:0030055
GeneOntologyCellularComponentexternal encapsulating structure

TSPAN9 PKHD1L1

1.36e-0265862GO:0030312
DomainTetraspanin_CS

TSPAN4 TSPAN9

1.80e-052162IPR018503
DomainTM4_1

TSPAN4 TSPAN9

2.79e-052662PS00421
DomainTetraspanin

TSPAN4 TSPAN9

4.25e-053262IPR000301
DomainTetraspanin_EC2

TSPAN4 TSPAN9

4.25e-053262IPR008952
DomainTetraspanin/Peripherin

TSPAN4 TSPAN9

4.52e-053362IPR018499
DomainTetraspannin

TSPAN4 TSPAN9

4.52e-053362PF00335
Domain-

SEMA3G PKHD1L1

1.72e-02663622.60.40.10
DomainIg-like_fold

SEMA3G PKHD1L1

1.93e-0270662IPR013783
Pubmed

Mitocytosis, a migrasome-mediated mitochondrial quality-control process.

TSPAN4 TSPAN9

1.12e-06106234048705
Pubmed

Appearance of new tetraspanin genes during vertebrate evolution.

TSPAN4 TSPAN9

4.71e-06206218291621
Pubmed

Complexes of tetraspanins with integrins: more than meets the eye.

TSPAN4 TSPAN9

6.83e-06246211739647
Pubmed

Analysis of the myosin-II-responsive focal adhesion proteome reveals a role for β-Pix in negative regulation of focal adhesion maturation.

TSPAN4 TSPAN9

9.82e-042856221423176
Pubmed

Transcriptome analysis of human gastric cancer.

PRSS36 TSPAN4

6.96e-037726216341674
Pubmed

Novel genetic loci identified for the pathophysiology of childhood obesity in the Hispanic population.

SLCO3A1 PKHD1L1

7.71e-038146223251661
GeneFamilyCD molecules|Tetraspanins

TSPAN4 TSPAN9

3.22e-053352768
CoexpressionCHIARADONNA_NEOPLASTIC_TRANSFORMATION_KRAS_DN

TSPAN4 SLCO3A1

4.25e-0414162M10381
CoexpressionCHIARADONNA_NEOPLASTIC_TRANSFORMATION_KRAS_DN

TSPAN4 SLCO3A1

4.56e-0414662MM973
CoexpressionGSE40274_EOS_VS_FOXP3_AND_EOS_TRANSDUCED_ACTIVATED_CD4_TCELL_UP

TSPAN4 TSPAN9

5.00e-0415362M9151
CoexpressionAKT_UP_MTOR_DN.V1_DN

TSPAN4 SLCO3A1

7.30e-0418562M2664
CoexpressionAKT_UP.V1_DN

TSPAN4 SLCO3A1

7.45e-0418762M2666
CoexpressionGSE13738_RESTING_VS_TCR_ACTIVATED_CD4_TCELL_UP

TSPAN9 SLCO3A1

8.10e-0419562M3319
CoexpressionGSE46242_CTRL_VS_EGR2_DELETED_ANERGIC_TH1_CD4_TCELL_UP

SLCO3A1 SEMA3G

8.18e-0419662M9707
CoexpressionGSE22601_DOUBLE_POSITIVE_VS_CD4_SINGLE_POSITIVE_THYMOCYTE_UP

PRSS36 SLCO3A1

8.18e-0419662M6227
CoexpressionGSE3982_NEUTROPHIL_VS_BASOPHIL_UP

SLCO3A1 SEMA3G

8.18e-0419662M5524
CoexpressionGSE2405_HEAT_KILLED_VS_LIVE_A_PHAGOCYTOPHILUM_STIM_NEUTROPHIL_24H_DN

PRSS36 SLCO3A1

8.26e-0419762M6219
CoexpressionGSE2405_0H_VS_9H_A_PHAGOCYTOPHILUM_STIM_NEUTROPHIL_UP

PRSS36 SLCO3A1

8.35e-0419862M6217
CoexpressionGSE2706_UNSTIM_VS_8H_R848_DC_UP

PRSS36 TSPAN4

8.35e-0419862M4693
CoexpressionGSE21063_WT_VS_NFATC1_KO_BCELL_UP

TSPAN4 PKHD1L1

8.52e-0420062M8260
CoexpressionGSE27786_CD4_TCELL_VS_NKTCELL_DN

TSPAN4 SLCO3A1

8.52e-0420062M4825
CoexpressionGSE27786_NKCELL_VS_NEUTROPHIL_DN

SLCO3A1 SEMA3G

8.52e-0420062M4859
CoexpressionGSE19198_CTRL_VS_IL21_TREATED_TCELL_6H_UP

TSPAN4 SLCO3A1

8.52e-0420062M7221
CoexpressionGSE7460_TCONV_VS_TREG_THYMUS_UP

SLCO3A1 PKHD1L1

8.52e-0420062M5675
CoexpressionGSE17580_TREG_VS_TEFF_S_MANSONI_INF_DN

TSPAN9 SLCO3A1

8.52e-0420062M3674
CoexpressionGSE13306_LAMINA_PROPRIA_VS_SPLEEN_TREG_DN

TSPAN4 TSPAN9

8.52e-0420062M3219
CoexpressionGSE24142_EARLY_THYMIC_PROGENITOR_VS_DN3_THYMOCYTE_FETAL_UP

TSPAN4 SLCO3A1

8.52e-0420062M4570
CoexpressionMIKKELSEN_MEF_ICP_WITH_H3K27ME3

PRSS36 PKHD1L1

9.12e-0420762M1963
CoexpressionMIKKELSEN_MEF_ICP_WITH_H3K27ME3

PRSS36 PKHD1L1

1.06e-0322362MM838
CoexpressionCONCANNON_APOPTOSIS_BY_EPOXOMICIN_UP

TSPAN9 SLCO3A1

1.21e-0323962M4716
CoexpressionAtlasStromal Cells, BEC.MLN, gp38- CD31+, Lymph Node, avg-5

TSPAN4 TSPAN9 SEMA3G

1.88e-0445663GSM777032_500
CoexpressionAtlasStromal Cells, BEC.SLN, gp38- CD31+, Lymph Node, avg-4

TSPAN4 TSPAN9 SEMA3G

1.91e-0445963GSM777037_500
ToppCelldroplet-Lung-LUNG-1m-Endothelial-endothelial_cell_of_lymphatic_vessel|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TSPAN4 SLCO3A1 PKHD1L1

1.40e-06187639c9ae8725905ba0cfe407878006ed06c2480fb72
ToppCelldroplet-Lung-LUNG-1m-Endothelial-Lymphatic_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TSPAN4 SLCO3A1 PKHD1L1

1.40e-06187639e9460e57cdc9cd0a0de2866b140e06d0bc19a8f
ToppCellAdult-Endothelial|Adult / Lineage, Cell type, age group and donor

TSPAN9 SEMA3G PKHD1L1

1.56e-0619463963b3fbee0575af8379baa397ace65949eaf34f7
ToppCellBiopsy_IPF-Endothelial|Biopsy_IPF / Sample group, Lineage and Cell type

TSPAN9 SEMA3G PKHD1L1

1.71e-06200637ccd3b617838b39da814278dc0e12384013401ce
ToppCellBronchial-10x5prime-Endothelial|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

TSPAN9 SEMA3G PKHD1L1

1.71e-0620063ad34c978cc6b89b4c1c8c9b2fb2a938051b555a0
ToppCellBiopsy_Control_(H.)-Endothelial|Biopsy_Control_(H.) / Sample group, Lineage and Cell type

TSPAN9 SEMA3G PKHD1L1

1.71e-06200636a9b6a4b4f204598290ae21c87ddb42ac95dfc4c
ToppCellBronchial-NucSeq-Endothelial-Endothelia_vascular-VE_systemic_arterial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

TSPAN9 SEMA3G

1.96e-04164623cd80e6275f0f9b5667912139d15ebf5e6b17f2f
ToppCell343B-Lymphocytic-Plasma_cell|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

SEMA3G PKHD1L1

1.96e-0416462cf62d34ce9dd220fe61748466c84fd70d9ba697c
ToppCell343B-Lymphocytic-Plasma_cell-|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

SEMA3G PKHD1L1

1.96e-0416462e00549bc8b3a5566f39031f39d7e698b0b107a7f
ToppCellPBMC-Mild-Hematopoietic-Platelet-Platelet-plt_0|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

TSPAN9 PKHD1L1

1.99e-04165628329d780f244bc31344443b29e5a00529a016662
ToppCellPBMC-Mild-Hematopoietic-Platelet-Platelet-plt_0|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

TSPAN9 PKHD1L1

1.99e-04165626799a6580c667738995cceb31cbf1c7fbdc4ff84
ToppCellfacs-Brain_Myeloid-Hippocampus-24m-Myeloid-nan|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TSPAN4 TSPAN9

2.03e-0416762a21a2b301d0a3d7a41e605f7a3c37548962a331d
ToppCellfacs-Brain_Myeloid-Hippocampus-24m|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TSPAN4 TSPAN9

2.03e-04167620e746483773bde6582874a33591ab2a578d724eb
ToppCellfacs-Brain_Myeloid-Hippocampus-24m-Myeloid|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TSPAN4 TSPAN9

2.03e-04167627f3224af9b30082b927a822b91f96e0c88151b4e
ToppCellAdult-Endothelial-endothelial_cell_of_artery-D122|Adult / Lineage, Cell type, age group and donor

TSPAN9 SEMA3G

2.06e-04168628c3e1e45b422813bcdfa4273b1167db649a312f5
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Glomerular_Capillary_Endothelial_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

SEMA3G PKHD1L1

2.08e-0416962987ff79ad563825dd9877ea8ccb536758f8c6700
ToppCelldroplet-Heart-HEART_(LV+RV_ONLY)-30m-Hematologic-fibroblast|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PRSS36 SEMA3G

2.08e-041696215a9183c838cc6384d7f5dfeae3d30602964c9b3
ToppCellfacs-Brain_Myeloid-Hippocampus-24m-Myeloid-microglial_cell|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TSPAN4 TSPAN9

2.11e-0417062b4f2c05db2c2591561fd42febc72eed3b5e8f9fb
ToppCellHealthy/Control-Plasmablast|World / Disease group and Cell class

SEMA3G PKHD1L1

2.16e-0417262d3bfcf5d936152b71cd90f955f9331709edd979e
ToppCell5'-Adult-LargeIntestine-Endothelial-lymphatic_endothelial-LEC3_(ADGRG3+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TSPAN4 PKHD1L1

2.18e-04173627dc988fc0ba29990567bf1bcdeb3faeeee507eb1
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Glomerular_Capillary_Endothelial_Cell_prolif|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SLCO3A1 PKHD1L1

2.18e-0417362f193c63cc536d891c9d23043765e320252bb6e65
ToppCellsevere_influenza-Plasmablast|severe_influenza / disease group, cell group and cell class (v2)

SEMA3G PKHD1L1

2.21e-04174628c6c4d794373e774ecb3382cb7163b4246b98780
ToppCellsystemic_lupus_erythematosus-managed-Lymphocytic_B-B_plasma-male|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

SEMA3G PKHD1L1

2.21e-0417462bdbaf805a94b2f5a0065933dab6bf84e3cabd525
ToppCellAdult-Endothelial-endothelial_cell_of_vein-D231|Adult / Lineage, Cell type, age group and donor

TSPAN9 PKHD1L1

2.21e-04174622dd647c4fdf99fd1f7b838efef01baf2cbc3446d
ToppCellHealthy/Control-Plasmablast|Healthy/Control / Disease group and Cell class

SEMA3G PKHD1L1

2.21e-041746297d19ef3240a1f648c6befaabb9ce45ad469cbce
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Myeloid-Monocytic-Nonclassical_Monocyte-Mono_c5-CD16|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

TSPAN4 PKHD1L1

2.23e-0417562dc7721794162dee96944f4b4b87b5681bb02ea8f
ToppCellInfluenza_Severe-Plasmablast|World / Disease group and Cell class

SEMA3G PKHD1L1

2.23e-041756214df8fc6f6beae1be7b7bd5837546d1ac1239a6f
ToppCellsystemic_lupus_erythematosus-flare-Lymphocytic_B-plasmablast-female|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

SEMA3G PKHD1L1

2.23e-04175623b5346fba617292de71963b6175e85a4f182fe30
ToppCellInfluenza_Severe-Plasmablast|Influenza_Severe / Disease group and Cell class

SEMA3G PKHD1L1

2.23e-04175623f9b9793d3d1b7a9b97899272b6a0d37b05c11d1
ToppCellfacs-Trachea-24m-Endothelial-endothelial_cell_of_trachea-tracheal_endothelial_cell-tracheal_endothelial_cell_l54|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

TSPAN9 PKHD1L1

2.26e-0417662460cb302c5b3d609c65b924e1d4e8ea057a68485
ToppCellControl-Lymphoid_P|Control / Disease group, lineage and cell class

SEMA3G PKHD1L1

2.26e-0417662d895a6b295cd649273ff80ad7785a3e0ae4c728a
ToppCell3'-Adult-LargeIntestine-Endothelial-lymphatic_endothelial-LEC3_(ADGRG3+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TSPAN4 PKHD1L1

2.26e-04176625d3b2395bb842eea39175f5af6a4c76527e2fc31
ToppCellControl-Lymphoid_P-Plasmablast|Control / Disease group, lineage and cell class

SEMA3G PKHD1L1

2.26e-04176624b4416f342b732d2cc60133838728880326257d8
ToppCellAdult-Endothelial-endothelial_cell_of_vein|Adult / Lineage, Cell type, age group and donor

TSPAN9 PKHD1L1

2.26e-0417662043683c61c5d1a7f8a4666a612310246bd3d83a2
ToppCell5'-Adult-Appendix-Endothelial-lymphatic_endothelial-LEC5_(CLDN11+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TSPAN4 TSPAN9

2.28e-04177623a85aa2bf3f2fdbea57d22d68e022cb3f6c2eb65
ToppCell5'-Adult-LargeIntestine-Endothelial-lymphatic_endothelial-LEC1_(ACKR4+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TSPAN9 PKHD1L1

2.28e-0417762b1775e05c28883a15c56628028770bc59d3233fb
ToppCellPBMC_fresh-frozen-Mild-Moderate_convalescent_d36-51-Lymphocytic-Lymphocytic_B-Plasma_cell|Mild-Moderate_convalescent_d36-51 / Compartment, severity and other cell annotations on 10x 3' data (130k)

SEMA3G PKHD1L1

2.31e-0417862693f1135d9c5545945e80c7ba3d098afc0ccac29
ToppCellfacs-Lung-3m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell-pulmonary_artery_endothelial_cell_l27|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

TSPAN4 PKHD1L1

2.31e-04178629f59a9af232d77bb55603a7776dbf9749ea652f2
ToppCellPBMC_fresh-frozen-Mild-Moderate_convalescent_d36-51-Lymphocytic-Lymphocytic_B-Plasma_cell-B_c05-MZB1-XBP1|Mild-Moderate_convalescent_d36-51 / Compartment, severity and other cell annotations on 10x 3' data (130k)

SEMA3G PKHD1L1

2.31e-04178626765c6970b1f2b719a20d2afd7471e1c262f3fc4
ToppCell5'-Adult-LymphNode-Endothelial-lymphatic_endothelial-LEC5_(CLDN11+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TSPAN4 PKHD1L1

2.31e-04178624b3ea0921bc598ebb9f63780ecdf8ad4349f3666
ToppCelldroplet-Fat-Bat-18m-Endothelial-nan|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TSPAN9 SEMA3G

2.34e-04179629863ab3ceb160a4b1d9790033a4ac48845863d65
ToppCelldroplet-Fat-Bat-18m-Endothelial|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TSPAN9 SEMA3G

2.34e-0417962dfe110add7228cd834b35916cbcc849769a01bb9
ToppCell5'-Adult-LargeIntestine-Endothelial-lymphatic_endothelial-LEC5_(CLDN11+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TSPAN4 PKHD1L1

2.34e-041796240c65e8623547aeb80f9cd2366e29072467ce069
ToppCelldroplet-Fat-Bat-18m-Endothelial-endothelial_cell|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TSPAN9 SEMA3G

2.34e-0417962e6224864eb76a2e9c1fc0c61513d9e936bb5c72c
ToppCelldroplet-Marrow-BM-1m-Hematologic-hematopoietic_precursor_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TSPAN4 SLCO3A1

2.36e-0418062ff34195bb7325e61fbf823c103c5e6115d8f1248
ToppCell10x5'v1-week_17-19-Myeloid_macrophage-stroma-monocytoid_macrophage|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

PRSS36 TSPAN4

2.36e-0418062ba4c1fb55e8f1095bea6968417fefcf5f700926b
ToppCelldroplet-Heart-HEART_(LV+RV_ONLY)-30m-Endothelial-endocardial_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TSPAN9 PKHD1L1

2.39e-0418162cef034030e6b029a49ae56be37ea1fac1a5c350e
ToppCell3'-Adult-LymphNode-Endothelial-lymphatic_endothelial-LEC5_(CLDN11+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TSPAN4 PKHD1L1

2.42e-041826282d6f72649c7dd4d64a84a9795edebdef2f285d6
ToppCellE15.5-Endothelial-large_vessel_endothelial_cell|E15.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

SLCO3A1 SEMA3G

2.42e-0418262345d0f9d5ee30434bc2aac17608ccdc9e61c8fa3
ToppCell5'-Adult-LymphNode-Endothelial-lymphatic_endothelial-LEC1_(ACKR4+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TSPAN4 PKHD1L1

2.44e-04183622d0d3b486498a7903fa9a1f48b189291da49c430
ToppCell10x5'-bone_marrow-Hematopoietic_Erythro-Mega-Megakaryocyte_early|bone_marrow / Manually curated celltypes from each tissue

TSPAN9 PKHD1L1

2.44e-04183623cc9f3dc3bc4bde1d3408b0a6ba58e135a11036d
ToppCell10x5'v1-week_17-19-Hematopoietic-MK-MK|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

TSPAN9 PKHD1L1

2.44e-04183629c66a40c355387f805dbdca4162dd05af5c1d8d4
ToppCellCOVID-19-Endothelial_cells-Arterial_endothelial_cells|COVID-19 / group, cell type (main and fine annotations)

TSPAN9 SEMA3G

2.47e-04184620f19494789f38ab1a420545e15e748ca7eb345c3
ToppCellcontrol-Others-Megakaryocytes|control / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs

TSPAN9 PKHD1L1

2.47e-0418462213915f2889ce8ecbe5f7b19bc2b24ed8c5efe1d
ToppCellcontrol-Others|control / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs

TSPAN9 PKHD1L1

2.47e-0418462a63b39fcc570b554cf10e8e47c2c1e079034768f
ToppCellfacs-Trachea-nan-24m-Endothelial|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TSPAN9 PKHD1L1

2.50e-0418562dec60254204014083ff3b4aec0cc75410950a486
ToppCellBAL-Severe-Myeloid-Macrophage|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)

PRSS36 TSPAN4

2.50e-04185629aea5ed8f9cee5ee933891203aac7adb85d68201
ToppCellBAL-Severe-Myeloid-Macrophage|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

PRSS36 TSPAN4

2.50e-0418562ae966929fb5bbb08ffcbac76cb21941638727f55
ToppCellSevere_COVID-19-Myeloid-transitional_Macro|Severe_COVID-19 / Disease group,lineage and cell class （2021.01.30）

PRSS36 TSPAN4

2.50e-0418562f7ef0d7740b4cfedc38846e802898c402dc411fd
ToppCellBAL-Severe-Myeloid-Macrophage-transitional_Macro-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

PRSS36 TSPAN4

2.50e-04185623beebaa92275086b1fae5f8c0c3d54016c5ba2aa
ToppCellEndothelial-A-Donor_08|World / lung cells shred on cell class, cell subclass, sample id

TSPAN9 SEMA3G

2.50e-0418562dee0b7ba2f338f0979d2306aedf52ac35a36b60c
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_with-steroid-Hematopoietic-Megakaryocytic|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

TSPAN9 PKHD1L1

2.50e-04185620ca99fcbd30c454bcdc2aa5265a0e4dba25666ea
ToppCellBAL-Severe-Myeloid-Macrophage-transitional_Macro-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

PRSS36 TSPAN4

2.50e-0418562ceff11cfa679147ccfd0a0f8079e697a6bea34d9
ToppCellBAL-Severe-Myeloid-Macrophage-transitional_Macro|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)

PRSS36 TSPAN4

2.50e-041856242939b294ea3e871274d8b73124c850dc1904fd2
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_with-steroid-Hematopoietic-Megakaryocytic-Megakaryocyte-Mega|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

TSPAN9 PKHD1L1

2.50e-04185620f722ffcc3e78d5c6b1b79d31d00929801a993f1
ToppCellAdult-Endothelial-capillary_endothelial_cell_(Cap1)-D231|Adult / Lineage, Cell type, age group and donor

TSPAN9 SEMA3G

2.50e-041856207f9f38f0739d7c830641723a38385550ac1ac92
ToppCellChildren_(3_yrs)-Endothelial-endothelial_cell_of_artery-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

TSPAN9 SEMA3G

2.50e-0418562a7ae76058b2082020cadec49d63b9f4e24d21734
ToppCellfacs-Trachea-nan-24m-Endothelial-nan|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TSPAN9 PKHD1L1

2.50e-0418562201465dc0d7aa0336a36d37805cae1155a5adfe1
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_with-steroid-Hematopoietic|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

TSPAN9 PKHD1L1

2.50e-0418562c985a4b184d382a79aaff07f81c0efede2c2d493
ToppCellfacs-Trachea-nan-24m-Endothelial-endothelial_cell|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TSPAN9 PKHD1L1

2.50e-0418562334f006c3ef33338ff8d649309d3f448733a3a99
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_with-steroid-Hematopoietic-Megakaryocytic-Megakaryocyte|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

TSPAN9 PKHD1L1

2.50e-0418562d0d0e000ebe1fc35a987930ceaf7e3369e0c694c
ToppCellBAL-Severe-Myeloid-Macrophage-transitional_Macro|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

PRSS36 TSPAN4

2.50e-04185627a3612520ae4f0cd61480eadba31eecce001419d
ToppCell5'-Adult-SmallIntestine-Endothelial-lymphatic_endothelial-LEC5_(CLDN11+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TSPAN4 PKHD1L1

2.52e-04186629579180db2a0bf3f043b4d169f9a08cdc45b459a
ToppCelldroplet-Marrow-nan-21m-Lymphocytic-naive_T_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TSPAN4 TSPAN9

2.52e-0418662744bf39af2fb5a7454477174d7755a6d78cd279f
ToppCellsevere-Others|severe / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs

TSPAN9 PKHD1L1

2.52e-0418662234a4bc7c3529daf8804f2a366887d02a47075cd
ToppCellAdult-Endothelial-endothelial_cell_of_artery|Adult / Lineage, Cell type, age group and donor

TSPAN9 SEMA3G

2.52e-04186622d1c4ea2e401db89971582ee54618a8b0c81b8ac
ToppCell(4)_Lymph_vessel|World / Oesophagus cell shreds on cell class (v1) and cell subclass (v1)

TSPAN4 PKHD1L1

2.52e-04186626b3afc2ae870ff73e30a60ce84fcee0eb365d809
ToppCell10x5'v1-week_17-19-Hematopoietic-MK|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

TSPAN9 PKHD1L1

2.55e-041876234cad5ac8602fe88ca3d421257190c9a388d4cb0
ToppCelldroplet-Lung-18m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SEMA3G PKHD1L1

2.55e-041876283930ef55191eff9006113feaeabb3c2fa21fd05
ToppCellControl-Endothelial_cells-Arterial_endothelial_cells|Control / group, cell type (main and fine annotations)

TSPAN9 SEMA3G

2.55e-041876281affaab3fe3e1daea45ada6445e906ddd33950e
ToppCellsevere-Others-Megakaryocytes|severe / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs

TSPAN9 PKHD1L1

2.55e-0418762ef16331d1e5abe6bde7f09793c4a87a6ac24e592
ToppCelldroplet-Lung-18m-Endothelial-arterial_endothelial|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SEMA3G PKHD1L1

2.55e-041876212129e02638c20d9b7c1c6e512d48bfd966e1029
ToppCellControl-Endothelial_cells-Endothelial_cells_(general)|Control / group, cell type (main and fine annotations)

TSPAN9 SEMA3G

2.55e-0418762fb5bcbc8effdbf0e57fcb71aca990a4aa0d65ce8
ToppCellChildren_(3_yrs)-Endothelial-capillary_endothelial_cell_(Cap1)-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

TSPAN9 SEMA3G

2.58e-0418862117dc80fa940e6aa1b0187a43fdde33f3fcb578f
ToppCell10x5'v1-week_17-19-Hematopoietic|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

TSPAN9 PKHD1L1

2.58e-0418862c00ba0abd0c7bb2c8f9166a2ac6220aae4f4d857
ToppCellASK428-Endothelial-Lymphatic|ASK428 / Donor, Lineage and Cell class of Lung cells from Dropseq

TSPAN9 PKHD1L1

2.58e-0418862c371bc340966cfe9205cbf4b62c6452f49f2559f
ToppCell5'-Adult-Distal_Rectal-Endothelial-lymphatic_endothelial-LEC6_(ADAMTS4+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TSPAN4 PKHD1L1

2.58e-0418862524a12f433c7b6f33fad36c0716afa06cd3235e9
ToppCelldroplet-Lung-1m-Endothelial-lymphatic_endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SLCO3A1 PKHD1L1

2.58e-0418862dc52dd2957be3f40001f0a56f3d9ac9d66ea466e
ToppCell5'-Adult-Distal_Rectal-Endothelial-lymphatic_endothelial|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TSPAN4 PKHD1L1

2.58e-0418862d2610b81b3c7f22977b5e2137b1f61410fc4ef16
ToppCelldroplet-Lung-1m-Endothelial-lymphatic_endothelial|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SLCO3A1 PKHD1L1

2.58e-04188622ef08313087e91985bcffc46c3798470cdeec49c
ToppCelldroplet-Lung-1m-Endothelial-lymphatic_endothelial-lymphatic_endothelial_cell|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SLCO3A1 PKHD1L1

2.58e-04188621f1604b6dc0a8ad0be3d9aac0bef448459c22465
ToppCellCOVID-19-lung-Artery_EC|lung / Disease (COVID-19 only), tissue and cell type

TSPAN9 SEMA3G

2.58e-0418862eecd7482b3c97d7f49993cb17edfab30c61232fc
ToppCellfacs-Marrow-KLS|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TSPAN4 SLCO3A1

2.60e-04189624214abfa07b047e256df43e472f9a835a18ed7a3
ToppCellEndothelial-endothelial_cell_of_artery|World / Lineage, Cell type, age group and donor

TSPAN9 SEMA3G

2.60e-0418962fdd89c71113ac99b7c800c6def8888e512ff1128
ToppCellfacs-Marrow-KLS-3m-Hematologic-hematopoietic_stem_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TSPAN4 SLCO3A1

2.60e-0418962533685a921a65d84107d8d33c43b4fffde019143
ToppCellfacs-Marrow-KLS-3m-Hematologic|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TSPAN4 SLCO3A1

2.60e-0418962dca56ab02bf0505f9a352ff907edaef30906d854
ToppCelldroplet-Trachea-3m-Endothelial-endothelial_cell_of_trachea-tracheal_endothelial_cell-tracheal_endothelial_cell_l10|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

TSPAN9 PKHD1L1

2.60e-041896228b9e96a5206b7fdae9b17daf05c8f5d24b6c5ec
ToppCelldroplet-Lung-18m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell-pulmonary_artery_endothelial_cell_l27|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

TSPAN4 PKHD1L1

2.63e-04190623cf464664d6aa22b212e60b70885953887e92483
ToppCellfacs-Trachea-24m-Endothelial-endothelial_cell_of_trachea-tracheal_endothelial_cell-tracheal_endothelial_cell_l27|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

TSPAN9 SEMA3G

2.63e-0419062632d5dc11765053366d61f0a0c7916111cea4f50
ToppCell3'-Parenchyma_lung-Endothelial-Blood_vessel_EC-pulmonary_artery_endothelial_cell-EC_arterial-EC_arterial_L.2.4.1.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

TSPAN9 SEMA3G

2.63e-0419062d0297d678498e346e56cf95fe9e3db7d3ad3b837
DrugMoroxidine hydrochloride [3160-91-6]; Up 200; 19.2uM; MCF7; HT_HG-U133A

TSPAN9 SLCO3A1 SEMA3G

1.29e-05199631527_UP
DrugNimodipine [66085-59-4]; Up 200; 9.6uM; HL60; HT_HG-U133A

TSPAN9 SLCO3A1

9.64e-04185623103_UP
DrugLoperamide hydrochloride [34552-83-5]; Up 200; 7.8uM; MCF7; HT_HG-U133A

TSPAN9 SLCO3A1

9.74e-04186621533_UP
DrugMethyl benzethonium chloride [25155-18-4]; Down 200; 8.6uM; HL60; HT_HG-U133A

TSPAN4 SEMA3G

1.03e-03191622190_DN
DrugMegestrol acetate [595-33-5]; Up 200; 10.4uM; MCF7; HT_HG-U133A

TSPAN9 SEMA3G

1.04e-03192625013_UP
DrugGraveoline [485-61-0]; Down 200; 14.4uM; MCF7; HT_HG-U133A

TSPAN9 SLCO3A1

1.05e-03193623614_DN
DrugIodixanol [92339-11-2]; Down 200; 2.6uM; MCF7; HT_HG-U133A

TSPAN9 SLCO3A1

1.06e-03194624848_DN
DrugHydroquinine hydrobromide hydrate [304695-81-6]; Up 200; 9.4uM; MCF7; HT_HG-U133A

TSPAN9 SLCO3A1

1.07e-03195622767_UP
DrugClemastine fumarate [14976-57-9]; Down 200; 8.6uM; MCF7; HT_HG-U133A

TSPAN9 SLCO3A1

1.08e-03196627485_DN
DrugProadifen hydrochloride [62-68-0]; Up 200; 10.2uM; HL60; HT_HG-U133A

TSPAN4 TSPAN9

1.08e-03196622707_UP
Drug3-Acetamidocoumarin [779-30-6]; Up 200; 19.6uM; MCF7; HT_HG-U133A

TSPAN9 SLCO3A1

1.08e-03196624426_UP
DrugClofazimine [2030-63-9]; Down 200; 8.4uM; MCF7; HT_HG-U133A

TSPAN9 SLCO3A1

1.08e-03196625642_DN
DrugGossypol [303-45-7]; Down 200; 7.8uM; MCF7; HT_HG-U133A

TSPAN9 SLCO3A1

1.08e-03196623637_DN
DrugDiflorasone Diacetate [33564-31-7]; Up 200; 8uM; MCF7; HT_HG-U133A

TSPAN9 SLCO3A1

1.08e-03196622798_UP
DrugMetoprolol-(+,-) (+)-tartrate salt [56392-17-7]; Down 200; 5.8uM; MCF7; HT_HG-U133A

TSPAN9 SLCO3A1

1.09e-03197626106_DN
Drug(-) -Levobunolol hydrochloride [27912-14-7]; Up 200; 12.2uM; MCF7; HT_HG-U133A

TSPAN9 SEMA3G

1.09e-03197624134_UP
DrugDiflorasone Diacetate [33564-31-7]; Down 200; 8uM; MCF7; HT_HG-U133A

TSPAN9 SEMA3G

1.09e-03197624158_DN
DrugGelsemine [509-15-9]; Up 200; 12.4uM; PC3; HT_HG-U133A

TSPAN9 SEMA3G

1.09e-03197624097_UP
DrugDipyridamole [58-32-2]; Up 200; 8uM; MCF7; HT_HG-U133A

TSPAN9 SEMA3G

1.09e-03197625252_UP
DrugCefazolin sodium salt [27164-46-1]; Up 200; 8.4uM; MCF7; HT_HG-U133A

TSPAN9 SEMA3G

1.09e-03197624708_UP
DrugMedrysone [2668-66-8]; Up 200; 11.6uM; PC3; HT_HG-U133A

TSPAN9 SEMA3G

1.09e-03197624266_UP
DrugAlclometasone dipropionate [667634-13-2]; Down 200; 7.6uM; HL60; HT_HG-U133A

TSPAN4 SEMA3G

1.09e-03197622532_DN
DrugRoxarsone [121-19-7]; Up 200; 15.2uM; PC3; HT_HG-U133A

TSPAN9 SLCO3A1

1.09e-03197625051_UP
DrugNeomycin sulfate [1405-10-3]; Up 200; 4.2uM; MCF7; HT_HG-U133A

SLCO3A1 SEMA3G

1.09e-03197622229_UP
DrugMetronidazole [443-48-1]; Up 200; 23.4uM; MCF7; HT_HG-U133A

TSPAN9 SEMA3G

1.09e-03197621503_UP
Drug(+)-Isoproterenol (+)-bitartrate salt [14638-70-1]; Up 200; 11uM; MCF7; HT_HG-U133A

TSPAN9 SLCO3A1

1.09e-03197625009_UP
Drug(+) -Levobunolol hydrochloride [47141-41-3]; Up 200; 12.2uM; MCF7; HT_HG-U133A

TSPAN9 SLCO3A1

1.09e-03197623355_UP
DrugBendroflumethiazide [73-48-3]; Down 200; 9.4uM; MCF7; HT_HG-U133A

TSPAN9 SLCO3A1

1.09e-03197623934_DN
DrugPhenformin hydrochloride [834-28-6]; Down 200; 16.6uM; MCF7; HT_HG-U133A

TSPAN9 SLCO3A1

1.09e-03197623622_DN
DrugProtoveratrine A [143-57-7]; Down 200; 5uM; MCF7; HT_HG-U133A

TSPAN4 TSPAN9

1.09e-03197624963_DN
DrugCotinine (-) [486-56-6]; Down 200; 22.6uM; MCF7; HT_HG-U133A

TSPAN9 SLCO3A1

1.10e-03198625246_DN
DrugPerhexiline maleate [6724-53-4]; Down 200; 10.2uM; MCF7; HT_HG-U133A

TSPAN4 TSPAN9

1.10e-03198625501_DN
DrugAtropine sulfate monohydrate [5908-99-6]; Up 200; 5.8uM; PC3; HT_HG-U133A

SLCO3A1 SEMA3G

1.10e-03198625865_UP
DrugBufexamac [2438-72-4]; Up 200; 18uM; MCF7; HT_HG-U133A

TSPAN9 SLCO3A1

1.10e-03198625515_UP
Drug0198306-0000 [212631-61-3]; Up 200; 10uM; MCF7; HT_HG-U133A

TSPAN9 SLCO3A1

1.10e-03198627064_UP
DrugReserpine [50-55-5]; Up 200; 6.6uM; MCF7; HT_HG-U133A

TSPAN9 SEMA3G

1.10e-03198623341_UP
DrugCholecalciferol [67-97-0]; Up 200; 10.4uM; MCF7; HT_HG-U133A

TSPAN9 SLCO3A1

1.10e-03198625002_UP
DrugHydrocotarnine hydrobromide [5985-00-2]; Up 200; 13.2uM; HL60; HG-U133A

TSPAN9 SEMA3G

1.10e-03198621772_UP
DrugLeucomisine [17946-87-1]; Up 200; 16.2uM; MCF7; HT_HG-U133A

TSPAN9 SLCO3A1

1.11e-03199626767_UP
DrugNitrofural [59-87-0]; Down 200; 20.2uM; MCF7; HT_HG-U133A

TSPAN4 TSPAN9

1.11e-03199625321_DN
DrugDisopyramide [3737-09-5]; Down 200; 11.8uM; HL60; HT_HG-U133A

TSPAN4 TSPAN9

1.11e-03199622408_DN
DrugBephenium hydroxynaphthoate [3818-50-6]; Down 200; 9uM; PC3; HT_HG-U133A

TSPAN9 SLCO3A1

1.11e-03199624668_DN
DrugPHA-00846566E [724718-26-7]; Up 200; 10uM; MCF7; HT_HG-U133A

TSPAN9 SLCO3A1

1.11e-03199627081_UP
Drugleukotoxin B (12,13-EODE); Down 200; 0.2uM; MCF7; HT_HG-U133A_EA

TSPAN4 SLCO3A1

1.11e-03199621108_DN
DrugDecamethonium bromide [541-22-0]; Down 200; 9.6uM; HL60; HT_HG-U133A

TSPAN4 SEMA3G

1.11e-03199622933_DN
DrugLidoflazine [3416-26-0]; Up 200; 8.2uM; MCF7; HT_HG-U133A

TSPAN9 SLCO3A1

1.11e-03199626278_UP
DrugPrimidone [125-33-7]; Down 200; 18.4uM; MCF7; HT_HG-U133A

TSPAN9 SLCO3A1

1.11e-03199625323_DN
DrugBacampicillin hydrochloride [37661-08-8]; Up 200; 8uM; PC3; HT_HG-U133A

TSPAN9 SLCO3A1

1.11e-03199624592_UP
DrugDiltiazem hydrochloride [33286-22-5]; Down 200; 8.8uM; MCF7; HT_HG-U133A

TSPAN4 TSPAN9

1.11e-03199625309_DN
DrugSulfamerazine [127-79-7]; Up 200; 15.2uM; MCF7; HT_HG-U133A

TSPAN9 SLCO3A1

1.13e-03200624740_UP
DrugBenzathine benzylpenicillin [5928-84-7]; Down 200; 4.2uM; HL60; HT_HG-U133A

TSPAN4 SEMA3G

1.13e-03200622939_DN
DrugSulfathiazole [72-14-0]; Up 200; 15.6uM; MCF7; HT_HG-U133A

SLCO3A1 SEMA3G

1.13e-03200624769_UP
DrugUrosiol [128-13-2]; Down 200; 10.2uM; HL60; HT_HG-U133A

TSPAN4 SEMA3G

1.13e-03200623105_DN
DrugUrapidil hydrochloride [64887-14-5]; Down 200; 9.4uM; HL60; HT_HG-U133A

TSPAN4 SEMA3G

1.13e-03200623078_DN
DrugTheobromine [83-67-0]; Up 200; 22.2uM; PC3; HT_HG-U133A

TSPAN9 SLCO3A1

1.13e-03200626613_UP
Diseasetelomere length

TSPAN9 SLCO3A1

1.64e-0331362EFO_0004505
DiseaseDNA methylation

TSPAN9 SLCO3A1

6.98e-0365662GO_0006306
Diseasewaist-hip ratio

TSPAN9 SLCO3A1

2.31e-02122662EFO_0004343

Protein segments in the cluster

PeptideGeneStartEntry
LLGGWWCHCLYGRQG

PRSS36

466

Q5K4E3
IGAWWGGFLLCGALL

SLCO3A1

261

Q9UIG8
MGHLWLLGIWGLCGL

PKHD1L1

1

Q86WI1
WLGGCGVLGVGIWLA

TSPAN4

21

O14817
WAICWLLGGLLLHGG

SEMA3G

6

Q9NS98
WLCGCGLLGVGIWLS

TSPAN9

21

O75954