Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionendopeptidase activity

TMPRSS9 PRSS3 KLK10 AZU1 PRSS56 PGC F7 CAPN13 ADAMTS7 PRSS27 CAPN7 PARL CTSB CTSK CTSL CTSV MASP2

1.79e-1043010917GO:0004175
GeneOntologyMolecularFunctionserine-type endopeptidase activity

TMPRSS9 PRSS3 KLK10 AZU1 PRSS56 F7 PRSS27 PARL CTSK CTSV MASP2

7.39e-0919010911GO:0004252
GeneOntologyMolecularFunctionserine-type peptidase activity

TMPRSS9 PRSS3 KLK10 AZU1 PRSS56 F7 PRSS27 PARL CTSK CTSV MASP2

1.80e-0820710911GO:0008236
GeneOntologyMolecularFunctionserine hydrolase activity

TMPRSS9 PRSS3 KLK10 AZU1 PRSS56 F7 PRSS27 PARL CTSK CTSV MASP2

2.30e-0821210911GO:0017171
GeneOntologyMolecularFunctionpeptidase activity

TMPRSS9 PRSS3 KLK10 AZU1 PRSS56 PGC F7 CAPN13 ADAMTS7 PRSS27 CAPN7 PARL CTSB CTSK CTSL CTSV MASP2

9.22e-0865410917GO:0008233
GeneOntologyMolecularFunctionkininogen binding

CTSB CTSL CTSV

1.57e-0651093GO:0030984
GeneOntologyMolecularFunctionbenzodiazepine receptor binding

RIMBP3 RIMBP3C RIMBP3B

1.57e-0651093GO:0030156
GeneOntologyMolecularFunctioncysteine-type endopeptidase activity

CAPN13 CAPN7 CTSB CTSK CTSL CTSV

7.60e-06861096GO:0004197
GeneOntologyMolecularFunctionproteoglycan binding

AZU1 CTSB CTSK CTSL CTSV

8.50e-06511095GO:0043394
GeneOntologyMolecularFunctiontransmembrane receptor protein tyrosine kinase activity

NTRK3 INSR IGF2R TIE1 LTK

2.81e-05651095GO:0004714
GeneOntologyMolecularFunctionserpin family protein binding

CTSL CTSV

2.95e-0521092GO:0097655
GeneOntologyMolecularFunctiontransmembrane receptor protein kinase activity

NTRK3 INSR IGF2R TIE1 LTK

1.02e-04851095GO:0019199
GeneOntologyMolecularFunctionprotein tyrosine kinase activity

HIPK4 NTRK3 INSR IGF2R TIE1 LTK

1.45e-041451096GO:0004713
GeneOntologyMolecularFunctioncysteine-type carboxypeptidase activity

CTSL CTSV

1.76e-0441092GO:0016807
GeneOntologyMolecularFunctionglucokinase activity

HK1 HKDC1

2.92e-0451092GO:0004340
GeneOntologyMolecularFunctionhexokinase activity

HK1 HKDC1

2.92e-0451092GO:0004396
GeneOntologyMolecularFunctionfructokinase activity

HK1 HKDC1

2.92e-0451092GO:0008865
GeneOntologyMolecularFunctionprotein-lysine 6-oxidase activity

LOXL2 LOXL4

2.92e-0451092GO:0004720
GeneOntologyMolecularFunctioncarbohydrate binding

CRYBG2 EPM2A HK1 HKDC1 LGALS1 IGF2R LOXL2 PKD1

3.01e-043101098GO:0030246
GeneOntologyMolecularFunctionpeptide binding

AVPR2 INSR SSTR5 CTSB TIMM22 CTSL CTSV NUP153

3.57e-043181098GO:0042277
GeneOntologyMolecularFunctioncysteine-type endopeptidase activator activity involved in apoptotic process

CTSK CTSL CTSV

5.21e-04291093GO:0008656
GeneOntologyMolecularFunctioncysteine-type peptidase activity

CAPN13 CAPN7 CTSB CTSK CTSL CTSV

6.52e-041921096GO:0008234
GeneOntologyMolecularFunctionpeptidase activator activity involved in apoptotic process

CTSK CTSL CTSV

6.99e-04321093GO:0016505
GeneOntologyMolecularFunctioninsulin-like growth factor II binding

INSR IGF2R

8.09e-0481092GO:0031995
GeneOntologyMolecularFunctioncollagen binding

CTSB CTSK CTSL CTSV

1.01e-03811094GO:0005518
GeneOntologyMolecularFunctionfibronectin binding

CTSK CTSL CTSV

1.16e-03381093GO:0001968
GeneOntologyMolecularFunctioncysteine-type exopeptidase activity

CTSL CTSV

1.29e-03101092GO:0070004
GeneOntologyMolecularFunctionmonosaccharide binding

HK1 HKDC1 LGALS1 IGF2R

1.83e-03951094GO:0048029
GeneOntologyMolecularFunctionD-glucose binding

HK1 HKDC1

2.57e-03141092GO:0005536
GeneOntologyMolecularFunctioncalcium ion binding

PRSS3 CUBN F7 CAPN13 THBS3 LOXL2 PCDH11X LTBP2 NOTCH1 NOTCH4 MASP2

2.62e-0374910911GO:0005509
GeneOntologyMolecularFunctioncysteine-type endopeptidase regulator activity involved in apoptotic process

CTSK CTSL CTSV

3.21e-03541093GO:0043028
GeneOntologyMolecularFunctionoxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor

LOXL2 LOXL4

3.37e-03161092GO:0016641
GeneOntologyMolecularFunctionWnt receptor activity

FZD1 PKD1

3.81e-03171092GO:0042813
GeneOntologyMolecularFunctioncalcium-dependent cysteine-type endopeptidase activity

CAPN13 CAPN7

3.81e-03171092GO:0004198
GeneOntologyMolecularFunctioncarbohydrate derivative transmembrane transporter activity

SLC37A3 SLC25A26 SLC25A47

4.12e-03591093GO:1901505
GeneOntologyMolecularFunctioninsulin-like growth factor binding

INSR IGF2R

4.75e-03191092GO:0005520
GeneOntologyMolecularFunctionoxidoreductase activity, acting on the CH-NH2 group of donors

LOXL2 LOXL4

5.26e-03201092GO:0016638
GeneOntologyMolecularFunctionoligosaccharide binding

LGALS1 LOXL2

5.26e-03201092GO:0070492
GeneOntologyMolecularFunctionphosphotransferase activity, alcohol group as acceptor

HK1 HIPK4 NTRK3 INSR HKDC1 DGKQ PANK1 IGF2R TIE1 LTK

5.42e-0370910910GO:0016773
GeneOntologyMolecularFunctioncarbohydrate kinase activity

HK1 HKDC1

5.79e-03211092GO:0019200
GeneOntologyBiologicalProcessthyroid hormone generation

TG CTSB CTSK CTSL CTSV

1.92e-07251105GO:0006590
GeneOntologyBiologicalProcessthyroid hormone metabolic process

TG CTSB CTSK CTSL CTSV

9.68e-07341105GO:0042403
GeneOntologyBiologicalProcesscollagen catabolic process

PRSS3 CTSB CTSK CTSL CTSV

9.21e-06531105GO:0030574
GeneOntologyBiologicalProcessmorphogenesis of a branching structure

FEM1B NTN4 TIE1 PKD1 CTNND2 CTSL CTSV NOTCH1 NOTCH4

1.01e-052581109GO:0001763
GeneOntologyBiologicalProcessanatomical structure maturation

PLA2G3 FEM1B NTN4 THBS3 ADAMTS7 FEV IFT80 CTSL CTSV NOTCH1

2.00e-0535411010GO:0071695
GeneOntologyBiologicalProcessmorphogenesis of a branching epithelium

FEM1B NTN4 TIE1 PKD1 CTSL CTSV NOTCH1 NOTCH4

3.92e-052361108GO:0061138
GeneOntologyBiologicalProcessbranching involved in lymph vessel morphogenesis

TIE1 PKD1

8.43e-0531102GO:0060854
GeneOntologyBiologicalProcessconnective tissue development

ITGB8 THBS3 LMNA ADAMTS7 LOXL2 PKD1 IFT80 CTSK NOTCH1

9.31e-053431109GO:0061448
GeneOntologyBiologicalProcessphenol-containing compound metabolic process

TG FEV CTSB CTSK CTSL CTSV

1.14e-041421106GO:0018958
GeneOntologyBiologicalProcessdevelopmental maturation

PLA2G3 FEM1B NTN4 THBS3 ADAMTS7 FEV IFT80 CTSL CTSV NOTCH1

1.21e-0443911010GO:0021700
GeneOntologyBiologicalProcesscollagen metabolic process

PRSS3 CTSB CTSK CTSL CTSV NOTCH1

1.43e-041481106GO:0032963
GeneOntologyBiologicalProcesspositive regulation of aorta morphogenesis

NOTCH1 NOTCH4

1.68e-0441102GO:1903849
GeneOntologyBiologicalProcessmodified amino acid metabolic process

PLA2G3 TG CTSB CTSK CTSL CTSV PCYOX1

1.69e-042181107GO:0006575
GeneOntologyBiologicalProcessextracellular matrix organization

NTN4 TIE1 ADAMTS7 LOXL2 FSHR LOXL4 CTSK CTSV NOTCH1

1.90e-043771109GO:0030198
GeneOntologyBiologicalProcessextracellular structure organization

NTN4 TIE1 ADAMTS7 LOXL2 FSHR LOXL4 CTSK CTSV NOTCH1

1.93e-043781109GO:0043062
GeneOntologyBiologicalProcessexternal encapsulating structure organization

NTN4 TIE1 ADAMTS7 LOXL2 FSHR LOXL4 CTSK CTSV NOTCH1

1.97e-043791109GO:0045229
GeneOntologyBiologicalProcesshair cycle phase

CTSL CTSV NOTCH1

2.42e-04231103GO:0044851
GeneOntologyBiologicalProcesspeptidyl-lysine oxidation

LOXL2 LOXL4

2.79e-0451102GO:0018057
GeneOntologyBiologicalProcesscarbohydrate phosphorylation

EPM2A HK1 HKDC1

3.12e-04251103GO:0046835
GeneOntologyBiologicalProcesscartilage development

ITGB8 THBS3 ADAMTS7 LOXL2 PKD1 IFT80 CTSK

3.28e-042431107GO:0051216
GeneOntologyBiologicalProcessregulation of aorta morphogenesis

NOTCH1 NOTCH4

4.17e-0461102GO:1903847
GeneOntologyBiologicalProcessepidermal cell fate specification

PTCH2 NOTCH1

4.17e-0461102GO:0009957
GeneOntologyCellularComponentendolysosome lumen

CTSB CTSK CTSL

1.45e-0651113GO:0036021
GeneOntologyCellularComponentcollagen-containing extracellular matrix

PRSS3 F7 LGALS1 NTN4 THBS3 LOXL2 LOXL4 LTBP2 CTSB CTSL CTSV

1.21e-0453011111GO:0062023
GeneOntologyCellularComponentlysosomal lumen

CUBN CTSB CTSK CTSL CTSV

1.77e-04981115GO:0043202
GeneOntologyCellularComponentextracellular matrix

PRSS3 F7 LGALS1 NTN4 THBS3 ADAMTS7 LOXL2 LOXL4 LTBP2 CTSB CTSL CTSV

1.91e-0465611112GO:0031012
GeneOntologyCellularComponentexternal encapsulating structure

PRSS3 F7 LGALS1 NTN4 THBS3 ADAMTS7 LOXL2 LOXL4 LTBP2 CTSB CTSL CTSV

1.97e-0465811112GO:0030312
GeneOntologyCellularComponentcell surface

INSR CUBN ITGB8 LGALS1 FZD1 IGF2R ADAMTS7 CD163L1 FSHR PKD1 CTSB CTSK CTSL CTSV NOTCH1 NOTCH4

2.54e-04111111116GO:0009986
GeneOntologyCellularComponentvacuolar lumen

AZU1 CUBN CTSB CTSK CTSL CTSV

3.79e-041781116GO:0005775
GeneOntologyCellularComponentmanchette

RIMBP3 RIMBP3C RIMBP3B

4.33e-04281113GO:0002177
GeneOntologyCellularComponentendolysosome

CTSB CTSK CTSL

5.33e-04301113GO:0036019
GeneOntologyCellularComponentendosome

FKBP15 AVPR2 PLA2G3 INSR DGKQ CUBN BIRC6 PANK1 IGF2R FSHR CTSB CTSK CTSL CTSV NOTCH1

1.29e-03116711115GO:0005768
GeneOntologyCellularComponentendosome lumen

CTSB CTSK CTSL

1.54e-03431113GO:0031904
MousePhenodetached acrosome

SPAG4 HIPK4 RIMBP3 FSHR RIMBP3C RIMBP3B

2.85e-0744876MP:0009231
MousePhenokinked sperm flagellum

HIPK4 PLA2G3 RIMBP3 FSHR RIMBP3C RIMBP3B

1.23e-0656876MP:0009237
MousePhenoectopic manchette

SPAG4 RIMBP3 RIMBP3C RIMBP3B

5.05e-0619874MP:0009377
MousePhenoabnormal sperm nucleus morphology

SPAG4 HIPK4 RIMBP3 FSHR RIMBP3C RIMBP3B

6.44e-0674876MP:0009232
MousePhenoperiodontal ligament necrosis

CTSL CTSV

3.83e-052872MP:0030515
MousePhenoabnormal lymph node medullary sinus morphology

CTSL CTSV

3.83e-052872MP:0011222
MousePhenodilated lymph node medullary sinus

CTSL CTSV

3.83e-052872MP:0011223
MousePhenoabnormal acrosome morphology

SPAG4 HIPK4 PLA2G3 RIMBP3 FSHR RIMBP3C RIMBP3B

5.88e-05159877MP:0008898
MousePhenoabnormal endocrine gland morphology

DMXL2 EPM2A KLK10 KLHL1 PARG INSR SSTR5 PGC TG SLC22A6 LMNA WDHD1 FSHR PKD1 PARL CTSB CTSL CTSV NOTCH1

6.21e-0511448719MP:0013560
MousePhenoamyloidosis

CTSB CTSK CTSL CTSV

6.32e-0535874MP:0000604
MousePhenoabnormal amyloid deposition

CTSB CTSK CTSL CTSV

6.32e-0535874MP:0021152
MousePhenoorthokeratosis

LMNA CTSL CTSV

1.23e-0416873MP:0009675
MousePhenoabnormal manchette morphology

SPAG4 RIMBP3 RIMBP3C RIMBP3B

1.72e-0445874MP:0009376
MousePhenoabnormal thyroid gland morphology

TG WDHD1 CTSB CTSL CTSV

2.06e-0487875MP:0000681
MousePhenoabnormal endometrial gland morphology

FZD1 IGF2R FSHR

2.46e-0420873MP:0009094
MousePhenodetached sperm flagellum

RIMBP3 RIMBP3C RIMBP3B

2.86e-0421873MP:0008893
MousePhenothymus atrophy

LMNA PARL CTSL CTSV

3.49e-0454874MP:0003644
MousePhenoheart hemorrhage

F7 ITGB8 IGF2R PKD1

3.75e-0455874MP:0009698
MousePhenofolliculitis

CTSL CTSV

3.78e-045872MP:0000376
MousePhenodental pulp necrosis

CTSL CTSV

3.78e-045872MP:0013251
MousePhenohair follicle outer root sheath hyperplasia

CTSL CTSV

3.78e-045872MP:0010688
MousePhenoenlarged thymus cortex

CTSL CTSV

3.78e-045872MP:0013593
MousePhenorough coat

LMNA CTSL CTSV

4.29e-0424873MP:0010179
MousePhenoincreased central memory CD4-positive, alpha-beta T cell number

TG CTSL CTSV

4.29e-0424873MP:0010841
MousePhenopremature bone ossification

THBS3 IGF2R PKD1

5.46e-0426873MP:0003416
MousePhenoinsulitis

CTSB CTSL CTSV

5.46e-0426873MP:0004031
DomainTHIOL_PROTEASE_CYS

CAPN13 CAPN7 CTSB CTSK CTSL CTSV

7.61e-09261106PS00139
DomainTHIOL_PROTEASE_ASN

CAPN13 CAPN7 CTSB CTSK CTSL CTSV

9.73e-09271106PS00640
DomainTHIOL_PROTEASE_HIS

CAPN13 CAPN7 CTSB CTSK CTSL CTSV

9.73e-09271106PS00639
DomainTRYPSIN_SER

TMPRSS9 PRSS3 KLK10 AZU1 PRSS56 F7 PRSS27 MASP2

2.09e-071061108PS00135
DomainTRYPSIN_HIS

TMPRSS9 PRSS3 KLK10 AZU1 PRSS56 F7 PRSS27 MASP2

2.25e-071071108PS00134
DomainPept_asp_AS

CTSB CTSK CTSL CTSV

2.33e-07101104IPR025661
DomainPeptidase_S1A

TMPRSS9 PRSS3 KLK10 AZU1 PRSS56 F7 PRSS27 MASP2

3.43e-071131108IPR001314
DomainPept_his_AS

CTSB CTSK CTSL CTSV

3.64e-07111104IPR025660
DomainTRYPSIN_DOM

TMPRSS9 PRSS3 KLK10 AZU1 PRSS56 F7 PRSS27 MASP2

3.93e-071151108PS50240
DomainTryp_SPc

TMPRSS9 PRSS3 KLK10 AZU1 PRSS56 F7 PRSS27 MASP2

4.48e-071171108SM00020
DomainPept_cys_AS

CAPN7 CTSB CTSK CTSL CTSV

5.70e-07281105IPR000169
DomainTrypsin

TMPRSS9 PRSS3 KLK10 AZU1 PRSS56 F7 PRSS27 MASP2

5.80e-071211108PF00089
DomainTrypsin_dom

TMPRSS9 PRSS3 KLK10 AZU1 PRSS56 F7 PRSS27 MASP2

5.80e-071211108IPR001254
DomainPeptidase_S1_PA

TMPRSS9 PRSS3 KLK10 AZU1 PRSS56 F7 PRSS27 MASP2

6.58e-071231108IPR009003
DomainPept_C1

CTSB CTSK CTSL CTSV

7.82e-07131104SM00645
DomainPeptidase_C1A_C

CTSB CTSK CTSL CTSV

7.82e-07131104IPR000668
DomainPeptidase_C1

CTSB CTSK CTSL CTSV

7.82e-07131104PF00112
DomainPeptidase_C1A

CTSB CTSK CTSL CTSV

7.82e-07131104IPR013128
DomainEGF_Ca-bd_CS

CUBN F7 THBS3 LTBP2 NOTCH1 NOTCH4 MASP2

1.68e-06971107IPR018097
DomainEGF_CA

CUBN F7 THBS3 LTBP2 NOTCH1 NOTCH4 MASP2

1.93e-06991107PS01187
DomainTRYPSIN_HIS

TMPRSS9 PRSS3 KLK10 PRSS56 F7 PRSS27 MASP2

2.52e-061031107IPR018114
DomainEGF_1

CUBN F7 ITGB8 NTN4 THBS3 TIE1 LTBP2 NOTCH1 NOTCH4 MASP2

2.67e-0625511010PS00022
DomainEGF-like_CS

CUBN F7 ITGB8 NTN4 THBS3 TIE1 LTBP2 NOTCH1 NOTCH4 MASP2

3.29e-0626111010IPR013032
DomainGrowth_fac_rcpt_

INSR CUBN NTN4 THBS3 TIE1 LTBP2 NOTCH1 NOTCH4

3.94e-061561108IPR009030
DomainInhibitor_I29

CTSK CTSL CTSV

6.84e-0671103PF08246
DomainProt_inhib_I29

CTSK CTSL CTSV

6.84e-0671103IPR013201
DomainInhibitor_I29

CTSK CTSL CTSV

6.84e-0671103SM00848
DomainEGF_CA

CUBN F7 THBS3 LTBP2 NOTCH1 NOTCH4 MASP2

7.78e-061221107SM00179
DomainEGF-like_Ca-bd_dom

CUBN F7 THBS3 LTBP2 NOTCH1 NOTCH4 MASP2

8.66e-061241107IPR001881
DomainEGF

CUBN F7 ITGB8 THBS3 TIE1 LTBP2 NOTCH1 NOTCH4 MASP2

1.05e-052351109SM00181
DomainEGF_CA

CUBN THBS3 LTBP2 NOTCH1 NOTCH4 MASP2

1.17e-05861106PF07645
DomainEGF_2

CUBN F7 ITGB8 THBS3 TIE1 LTBP2 NOTCH1 NOTCH4 MASP2

2.71e-052651109PS01186
DomainASX_HYDROXYL

CUBN F7 LTBP2 NOTCH1 NOTCH4 MASP2

2.77e-051001106PS00010
DomainTyr_kinase_rcpt_2_CS

NTRK3 INSR LTK

3.17e-05111103IPR002011
DomainM_domain

TNRC6C TNRC6A

3.44e-0521102PF12938
DomainGW182_M_dom

TNRC6C TNRC6A

3.44e-0521102IPR026805
DomainEGF-type_Asp/Asn_hydroxyl_site

CUBN F7 LTBP2 NOTCH1 NOTCH4 MASP2

3.85e-051061106IPR000152
DomainRECEPTOR_TYR_KIN_II

NTRK3 INSR LTK

4.21e-05121103PS00239
DomainEGF_3

CUBN F7 THBS3 TIE1 LTBP2 NOTCH1 NOTCH4 MASP2

7.58e-052351108PS50026
DomainEGF

CUBN F7 TIE1 LTBP2 NOTCH1 NOTCH4

1.01e-041261106PF00008
DomainAgo_hook

TNRC6C TNRC6A

1.03e-0431102PF10427
DomainTNRC6_PABC-bd

TNRC6C TNRC6A

1.03e-0431102IPR032226
DomainArgonaute_hook_dom

TNRC6C TNRC6A

1.03e-0431102IPR019486
DomainTNRC6-PABC_bdg

TNRC6C TNRC6A

1.03e-0431102PF16608
DomainEGF-like_dom

CUBN F7 THBS3 TIE1 LTBP2 NOTCH1 NOTCH4 MASP2

1.13e-042491108IPR000742
DomainTRYPSIN_SER

TMPRSS9 PRSS56 F7 PRSS27 MASP2

1.91e-04901105IPR033116
DomainNotch

NOTCH1 NOTCH4

2.05e-0441102IPR008297
DomainNODP

NOTCH1 NOTCH4

2.05e-0441102PF07684
DomainNotch_NODP_dom

NOTCH1 NOTCH4

2.05e-0441102IPR011656
DomainNotch_NOD_dom

NOTCH1 NOTCH4

2.05e-0441102IPR010660
DomainNOD

NOTCH1 NOTCH4

2.05e-0441102PF06816
DomainNOD

NOTCH1 NOTCH4

2.05e-0441102SM01338
DomainNODP

NOTCH1 NOTCH4

2.05e-0441102SM01339
DomainSRCR

CD163L1 LOXL2 LOXL4

2.45e-04211103PF00530
DomainLysyl_oxidase

LOXL2 LOXL4

3.40e-0451102IPR001695
DomainHexokinase_C

HK1 HKDC1

3.40e-0451102IPR022673
DomainHexokinase_N

HK1 HKDC1

3.40e-0451102IPR022672
DomainHexokinase_1

HK1 HKDC1

3.40e-0451102PF00349
DomainLYSYL_OXIDASE

LOXL2 LOXL4

3.40e-0451102PS00926
DomainHexokinase_2

HK1 HKDC1

3.40e-0451102PF03727
DomainLNR

NOTCH1 NOTCH4

3.40e-0451102PS50258
DomainHEXOKINASE_2

HK1 HKDC1

3.40e-0451102PS51748
DomainLysyl_oxidase_CS

LOXL2 LOXL4

3.40e-0451102IPR019828
DomainHexokinase_BS

HK1 HKDC1

3.40e-0451102IPR019807
DomainHEXOKINASE_1

HK1 HKDC1

3.40e-0451102PS00378
DomainLysyl_oxidase

LOXL2 LOXL4

3.40e-0451102PF01186
DomainSR

CD163L1 LOXL2 LOXL4

4.16e-04251103SM00202
Domain-

CD163L1 LOXL2 LOXL4

4.16e-042511033.10.250.10
DomainEGF_extracell

ITGB8 TIE1 LTBP2 NOTCH1

4.31e-04601104IPR013111
DomainEGF_2

ITGB8 TIE1 LTBP2 NOTCH1

4.31e-04601104PF07974
DomainSRCR_1

CD163L1 LOXL2 LOXL4

4.68e-04261103PS00420
DomainSRCR_2

CD163L1 LOXL2 LOXL4

4.68e-04261103PS50287
DomainSRCR-like_dom

CD163L1 LOXL2 LOXL4

4.68e-04261103IPR017448
DomainHexokinase

HK1 HKDC1

5.08e-0461102IPR001312
DomainSRCR

CD163L1 LOXL2 LOXL4

5.25e-04271103IPR001190
DomainNotch_dom

NOTCH1 NOTCH4

7.08e-0471102IPR000800
DomainNotch

NOTCH1 NOTCH4

7.08e-0471102PF00066
DomainNL

NOTCH1 NOTCH4

7.08e-0471102SM00004
DomainTyrKc

NTRK3 INSR TIE1 LTK

1.82e-03881104SM00219
DomainTyr_kinase_cat_dom

NTRK3 INSR TIE1 LTK

1.82e-03881104IPR020635
DomainFAD-dep_OxRdtase

FOXRED1 PCYOX1

2.18e-03121102IPR006076
DomainDAO

FOXRED1 PCYOX1

2.18e-03121102PF01266
DomainCalpain_domain_III

CAPN13 CAPN7

2.57e-03131102IPR022682
DomainCalpain_III

CAPN13 CAPN7

2.57e-03131102PF01067
DomainPROTEIN_KINASE_TYR

NTRK3 INSR TIE1 LTK

2.59e-03971104PS00109
DomainTyr_kinase_AS

NTRK3 INSR TIE1 LTK

2.59e-03971104IPR008266
DomainCalpain_cysteine_protease

CAPN13 CAPN7

2.99e-03141102IPR022684
DomainCysPc

CAPN13 CAPN7

3.43e-03151102SM00230
DomainPeptidase_C2_calpain_cat

CAPN13 CAPN7

3.43e-03151102IPR001300
DomainPeptidase_C2

CAPN13 CAPN7

3.43e-03151102PF00648
DomainCALPAIN_CAT

CAPN13 CAPN7

3.43e-03151102PS50203
DomainLRRNT

NTRK3 FSHR PKD1

3.76e-03531103PF01462
DomainGal_Oxase/kelch_b-propeller

KLHL1 LCMT2 KLHL20

5.09e-03591103IPR011043
PathwayREACTOME_EXTRACELLULAR_MATRIX_ORGANIZATION

PRSS3 ITGB8 CAPN13 LOXL2 CAPN7 LOXL4 LTBP2 CTSB CTSK CTSL CTSV

1.64e-072587811MM14572
PathwayREACTOME_TRAFFICKING_AND_PROCESSING_OF_ENDOSOMAL_TLR

CTSB CTSK CTSL CTSV

5.97e-0713784MM14659
PathwayREACTOME_TRAFFICKING_AND_PROCESSING_OF_ENDOSOMAL_TLR

CTSB CTSK CTSL CTSV

5.97e-0713784M593
PathwayREACTOME_EXTRACELLULAR_MATRIX_ORGANIZATION

ITGB8 CAPN13 NTN4 LOXL2 CAPN7 LOXL4 LTBP2 CTSB CTSK CTSL CTSV

7.40e-073007811M610
PathwayREACTOME_DEGRADATION_OF_THE_EXTRACELLULAR_MATRIX

PRSS3 CAPN13 CAPN7 CTSB CTSK CTSL CTSV

3.09e-06114787MM14571
PathwayREACTOME_ASSEMBLY_OF_COLLAGEN_FIBRILS_AND_OTHER_MULTIMERIC_STRUCTURES

LOXL2 LOXL4 CTSB CTSL CTSV

7.94e-0650785MM14796
PathwayREACTOME_RUNX1_REGULATES_TRANSCRIPTION_OF_GENES_INVOLVED_IN_DIFFERENTIATION_OF_KERATINOCYTES

CTSK CTSL CTSV

8.95e-068783M27796
PathwayREACTOME_ASSEMBLY_OF_COLLAGEN_FIBRILS_AND_OTHER_MULTIMERIC_STRUCTURES

LOXL2 LOXL4 CTSB CTSL CTSV

2.13e-0561785M27103
PathwayREACTOME_ACTIVATION_OF_MATRIX_METALLOPROTEINASES

PRSS3 CTSK CTSL CTSV

5.55e-0538784MM14611
PathwayREACTOME_ELASTIC_FIBRE_FORMATION

ITGB8 LOXL2 LOXL4 LTBP2

6.16e-0539784MM14601
PathwayREACTOME_COLLAGEN_FORMATION

LOXL2 LOXL4 CTSB CTSL CTSV

6.19e-0576785MM14573
PathwayREACTOME_ELASTIC_FIBRE_FORMATION

ITGB8 LOXL2 LOXL4 LTBP2

9.95e-0544784M26969
PathwayREACTOME_DEGRADATION_OF_THE_EXTRACELLULAR_MATRIX

CAPN13 CAPN7 CTSB CTSK CTSL CTSV

1.23e-04140786M587
PathwayREACTOME_COLLAGEN_FORMATION

LOXL2 LOXL4 CTSB CTSL CTSV

1.39e-0490785M631
PathwayREACTOME_COLLAGEN_DEGRADATION

PRSS3 CTSB CTSK CTSL

2.07e-0453784MM14566
PathwayWP_FATTY_ACIDS_AND_LIPOPROTEINS_TRANSPORT_IN_HEPATOCYTES

FKBP15 ECHDC1 CUBN DENND1B CD163L1 LOXL2 LOXL4 PCYOX1 HDLBP

2.46e-04381789M48063
PathwayREACTOME_HDL_CLEARANCE

CUBN HDLBP

2.99e-045782M27844
PathwayREACTOME_DEFECTIVE_LFNG_CAUSES_SCDO3

NOTCH1 NOTCH4

2.99e-045782M27411
PathwayREACTOME_PRE_NOTCH_PROCESSING_IN_GOLGI

NOTCH1 NOTCH4

2.99e-045782MM14733
PathwayKEGG_MEDICUS_PATHOGEN_SHIGELLA_FIMA_TO_CROSSTALK_BETWEEN_EXTRINSIC_AND_INTRINSIC_APOPTOTIC_PATHWAYS

HK1 HKDC1

4.47e-046782M47654
PathwayREACTOME_PRE_NOTCH_PROCESSING_IN_THE_ENDOPLASMIC_RETICULUM

NOTCH1 NOTCH4

4.47e-046782M27068
PathwayREACTOME_MHC_CLASS_II_ANTIGEN_PRESENTATION

CTSB CTSK CTSL CTSV KLC1

4.53e-04116785MM14855
PathwayREACTOME_DISEASES_ASSOCIATED_WITH_O_GLYCOSYLATION_OF_PROTEINS

THSD7B ADAMTS7 NOTCH1 NOTCH4

5.40e-0468784M27303
PathwayKEGG_LYSOSOME

IGF2R CTSB CTSK CTSL CTSV

5.49e-04121785M11266
PathwayREACTOME_PRE_NOTCH_EXPRESSION_AND_PROCESSING

NOTCH1 NOTCH4

6.23e-047782MM14734
PathwayREACTOME_POST_TRANSCRIPTIONAL_SILENCING_BY_SMALL_RNAS

TNRC6C TNRC6A

6.23e-047782M46421
PathwayREACTOME_MHC_CLASS_II_ANTIGEN_PRESENTATION

CTSB CTSK CTSL CTSV KLC1

6.60e-04126785M705
PathwayREACTOME_REGULATION_OF_PTEN_MRNA_TRANSLATION

TNRC6C TNRC6A

1.06e-039782M27810
PathwayREACTOME_REGULATION_OF_NPAS4_MRNA_TRANSLATION

TNRC6C TNRC6A

1.06e-039782M46436
PathwayREACTOME_REGULATION_OF_CDH11_MRNA_TRANSLATION_BY_MICRORNAS

TNRC6C TNRC6A

1.32e-0310782M48013
PathwayREACTOME_UPTAKE_OF_DIETARY_COBALAMINS_INTO_ENTEROCYTES

PRSS3 CUBN

1.32e-0310782M45024
PathwayKEGG_MEDICUS_REFERENCE_NOTCH_PROTEOLYTIC_ACTIVATION

NOTCH1 NOTCH4

1.61e-0311782M47865
PathwayREACTOME_ENDOSOMAL_VACUOLAR_PATHWAY

CTSL CTSV

1.61e-0311782M525
PathwayREACTOME_SIGNALING_BY_ALK_IN_CANCER

TNRC6C BIRC6 NOTCH1 KLC1

1.74e-0393784M42521
PathwayBIOCARTA_HES_PATHWAY

FZD1 NOTCH1

1.92e-0312782MM1562
PathwayBIOCARTA_HES_PATHWAY

FZD1 NOTCH1

1.92e-0312782M22042
PathwayKEGG_MEDICUS_PATHOGEN_HPV_E6_TO_NOTCH_SIGNALING_PATHWAY_N00380

NOTCH1 NOTCH4

1.92e-0312782M47532
PathwayKEGG_MEDICUS_PATHOGEN_HPV_E6_TO_NOTCH_SIGNALING_PATHWAY_N00381

NOTCH1 NOTCH4

1.92e-0312782M47533
PathwayREACTOME_SLC_TRANSPORTER_DISORDERS

HK1 AVPR2 SLC12A3 NUP153

2.19e-0399784M27474
PathwayKEGG_MEDICUS_REFERENCE_NOTCH_SIGNALING_PATHWAY

NOTCH1 NOTCH4

2.27e-0313782M47423
PathwayKEGG_MEDICUS_PATHOGEN_HPV_E6_TO_NOTCH_SIGNALING_PATHWAY_N00382

NOTCH1 NOTCH4

2.27e-0313782M47534
PathwayREACTOME_REGULATION_OF_NPAS4_GENE_EXPRESSION

TNRC6C TNRC6A

2.27e-0313782M46434
Pubmed

Thyroid functions of mouse cathepsins B, K, and L.

TG CTSB CTSK CTSL CTSV

3.46e-135114512782676
Pubmed

Cathepsin protease activity modulates amyloid load in extracerebral amyloidosis.

CTSB CTSK CTSL CTSV

1.09e-104114417068745
Pubmed

Osteoclastic bone degradation and the role of different cysteine proteinases and matrix metalloproteinases: differences between calvaria and long bone.

CTSB CTSK CTSL CTSV

1.09e-104114416939398
Pubmed

Cathepsin V, but not cathepsins L, B and K, may release angiostatin-like fragments from plasminogen.

CTSB CTSK CTSL CTSV

5.46e-105114418163891
Pubmed

Multiple sites on SARS-CoV-2 spike protein are susceptible to proteolysis by cathepsins B, K, L, S, and V.

CTSB CTSK CTSL CTSV

5.46e-105114433786919
Pubmed

Lysosomal processing of progranulin.

CTSB CTSK CTSL CTSV

7.59e-098114428835281
Pubmed

Asparagine endopeptidase controls anti-influenza virus immune responses through TLR7 activation.

CTSB CTSK CTSL CTSV

7.59e-098114422916010
Pubmed

Lysosomal proteolysis and autophagy require presenilin 1 and are disrupted by Alzheimer-related PS1 mutations.

IGF2R CTSB CTSL CTSV

2.26e-0810114420541250
Pubmed

Deletion of cysteine cathepsins B or L yields differential impacts on murine skin proteome and degradome.

CTSB CTSL CTSV

3.43e-083114323233448
Pubmed

Endosomal proteolysis of the Ebola virus glycoprotein is necessary for infection.

CTSB CTSL CTSV

3.43e-083114315831716
Pubmed

Proteolytic cleavage of the disease-related lysosomal membrane glycoprotein CLN7.

CTSB CTSL CTSV

3.43e-083114322668694
Pubmed

Cathepsin K activity-dependent regulation of osteoclast actin ring formation and bone resorption.

CTSK CTSL CTSV

3.43e-083114319028686
Pubmed

An intracellular serpin regulates necrosis by inhibiting the induction and sequelae of lysosomal injury.

CTSK CTSL CTSV

3.43e-083114317889653
Pubmed

Proteomic analysis of cathepsin B- and L-deficient mouse brain lysosomes.

CTSB CTSL CTSV

3.43e-083114317765022
Pubmed

Endosomal proteolysis by cathepsins is necessary for murine coronavirus mouse hepatitis virus type 2 spike-mediated entry.

CTSB CTSL CTSV

3.43e-083114316731916
Pubmed

Sequential, but not Concurrent, Incubation of Cathepsin K and L with Type I Collagen Results in Extended Proteolysis.

CTSK CTSL CTSV

3.43e-083114330931961
Pubmed

Cathepsin L and cathepsin B mediate reovirus disassembly in murine fibroblast cells.

CTSB CTSL CTSV

3.43e-083114311986312
Pubmed

Proteolytic disassembly is a critical determinant for reovirus oncolysis.

CTSB CTSL CTSV

3.43e-083114317519890
Pubmed

Expression of cysteine proteases in extraembryonic tissues during mouse embryogenesis.

CTSB CTSL CTSV

3.43e-083114310600178
Pubmed

Neuronal loss and brain atrophy in mice lacking cathepsins B and L.

CTSB CTSL CTSV

3.43e-083114312048238
Pubmed

Up-regulation of cathepsin B and cathepsin L activities in scrapie-infected mouse Neuro2a cells.

CTSB CTSL CTSV

3.43e-083114312867662
Pubmed

Cathepsin B & L are not required for ebola virus replication.

CTSB CTSL CTSV

3.43e-083114323236527
Pubmed

Antifibrotic effects of curcumin are associated with overexpression of cathepsins K and L in bleomycin treated mice and human fibroblasts.

CTSK CTSL CTSV

3.43e-083114322126332
Pubmed

Double deficiency of cathepsin B and L in the mouse pancreas alters trypsin activity without affecting acute pancreatitis severity.

CTSB CTSL CTSV

3.43e-083114336038449
Pubmed

Activation of cathepsins B and L in mouse lymphosarcoma tissue under the effect of cyclophosphamide is associated with apoptosis induction and infiltration by mononuclear phagocytes.

CTSB CTSL CTSV

3.43e-083114324319737
Pubmed

Redundancy between Cysteine Cathepsins in Murine Experimental Autoimmune Encephalomyelitis.

CTSB CTSL CTSV

1.37e-074114326075905
Pubmed

Identification of pathogenic T cell epitopes near cathepsin cleavage sites in thyroglobulin.

CTSB CTSL CTSV

1.37e-074114323315080
Pubmed

Expression of cathepsin proteinases by mouse trophoblast in vivo and in vitro.

CTSB CTSL CTSV

1.37e-074114310633857
Pubmed

Spatially and temporally defined lysosomal leakage facilitates mitotic chromosome segregation.

CTSB CTSL CTSV

1.37e-074114331932607
Pubmed

Lack of cathepsin activities alter or prevent the development of lung granulomas in a mouse model of sarcoidosis.

CTSK CTSL CTSV

1.37e-074114321251246
Pubmed

Cysteine cathepsins are essential in lysosomal degradation of α-synuclein.

CTSB CTSL CTSV

1.37e-074114326170293
Pubmed

A new pathway that regulates 53BP1 stability implicates cathepsin L and vitamin D in DNA repair.

LMNA CTSL CTSV

1.37e-074114321750527
Pubmed

Genetic and pharmacologic alteration of cathepsin expression influences reovirus pathogenesis.

CTSB CTSL CTSV

1.37e-074114319640986
Pubmed

Roles for cathepsins S, L, and B in insulitis and diabetes in the NOD mouse.

CTSB CTSL CTSV

1.37e-074114319664906
Pubmed

Unconventional Trafficking of Mammalian Phospholipase D3 to Lysosomes.

CTSB CTSL CTSV

1.37e-074114329386126
Pubmed

Lysosome associated membrane proteins maintain pancreatic acinar cell homeostasis: LAMP-2 deficient mice develop pancreatitis.

CTSB CTSL CTSV

1.37e-074114326693174
Pubmed

Participation of autophagy in storage of lysosomes in neurons from mouse models of neuronal ceroid-lipofuscinoses (Batten disease).

CTSB CTSL CTSV

1.37e-074114316314482
Pubmed

[The lysosomal cathepsins B, L and D in development of murine experimental leukemias].

CTSB CTSL CTSV

1.37e-074114320017393
Pubmed

RIM-BP3 is a manchette-associated protein essential for spermiogenesis.

RIMBP3 RIMBP3C RIMBP3B

1.37e-074114319091768
Pubmed

Cathepsin B and D deficiency in the mouse pancreas induces impaired autophagy and chronic pancreatitis.

CTSB CTSL CTSV

1.37e-074114333758261
Pubmed

Cathepsin expression during skeletal development.

CTSB CTSL CTSV

3.41e-075114310395917
Pubmed

Distinct roles for cysteine cathepsin genes in multistage tumorigenesis.

CTSB CTSL CTSV

3.41e-075114316481467
Pubmed

Analysis of protease activity in live antigen-presenting cells shows regulation of the phagosomal proteolytic contents during dendritic cell activation.

CTSB CTSL CTSV

3.41e-075114312186844
Pubmed

Important role of cathepsin S in generating peptides for TAP-independent MHC class I crosspresentation in vivo.

CTSB CTSL CTSV

3.41e-075114315308097
Pubmed

Asparagine endopeptidase is required for normal kidney physiology and homeostasis.

CTSB CTSL CTSV

3.41e-075114321292981
Pubmed

Maternal transmission of a humanised Igf2r allele results in an Igf2 dependent hypomorphic and non-viable growth phenotype.

IGF2R CTSL CTSV

3.41e-075114323468951
Pubmed

Role of Myeloperoxidase Oxidants in the Modulation of Cellular Lysosomal Enzyme Function: A Contributing Factor to Macrophage Dysfunction in Atherosclerosis?

CTSB CTSL CTSV

3.41e-075114327997605
Pubmed

Structure and evolution of RIM-BP genes: identification of a novel family member.

RIMBP3 RIMBP3C RIMBP3B

3.41e-075114317855024
Pubmed

Asparagine endopeptidase is not essential for class II MHC antigen presentation but is required for processing of cathepsin L in mice.

CTSB CTSL CTSV

3.41e-075114315905550
Pubmed

Ferrous iron-dependent drug delivery enables controlled and selective release of therapeutic agents in vivo.

CTSB CTSL CTSV

6.81e-076114324145449
Pubmed

DM, but not cathepsin L, is required to control an aerosol infection with Mycobacterium tuberculosis.

CTSB CTSL CTSV

6.81e-076114318591414
Pubmed

Mouse cathepsin M, a placenta-specific lysosomal cysteine protease related to cathepsins L and P.

CTSK CTSL CTSV

6.81e-076114310760593
Pubmed

Biogenesis and proteolytic processing of lysosomal DNase II.

CTSB CTSL CTSV

6.81e-076114323516607
Pubmed

IL-4 induces cathepsin protease activity in tumor-associated macrophages to promote cancer growth and invasion.

CTSB CTSL CTSV

6.81e-076114320080943
Pubmed

Biosynthetic processing of cathepsins and lysosomal degradation are abolished in asparaginyl endopeptidase-deficient mice.

CTSB CTSL CTSV

1.19e-067114312775715
Pubmed

Dual engagement of the NLRP3 and AIM2 inflammasomes by plasmodium-derived hemozoin and DNA during malaria.

CTSB CTSL CTSV

1.19e-067114324388751
Pubmed

A role for cathepsin E in the processing of mast-cell carboxypeptidase A.

CTSB CTSL CTSV

1.19e-067114315860733
Pubmed

The murine seminiferous epithelial cycle is pre-figured in the Sertoli cells of the embryonic testis.

LGALS1 CTSL CTSV

1.19e-067114311830565
Pubmed

TAILS N-Terminomics and Proteomics Show Protein Degradation Dominates over Proteolytic Processing by Cathepsins in Pancreatic Tumors.

CTSB CTSL CTSV

1.19e-067114327477282
Pubmed

Quantitative proteomic profiling of the extracellular matrix of pancreatic islets during the angiogenic switch and insulinoma progression.

PRSS3 LGALS1 LOXL2 LTBP2 CTSB CTSL CTSV

1.89e-06175114728071719
Pubmed

Serum Amyloid A-Mediated Inflammasome Activation of Microglial Cells in Cerebral Ischemia.

CTSB CTSL CTSV

1.90e-068114331611307
Pubmed

The expression and function of cystatin C and cathepsin B and cathepsin L during mouse embryo implantation and placentation.

CTSB CTSL CTSV

1.90e-06811439310336
Pubmed

The SPOT technique as a tool for studying protein tyrosine phosphatase substrate specificities.

NTRK3 INSR LTK

2.84e-069114312237455
Pubmed

Induced expression of cathepsins and cystatin C in a murine model of demyelination.

CTSB CTSL CTSV

2.84e-069114317086443
Pubmed

Cleavage of nidogen-1 by cathepsin S impairs its binding to basement membrane partners.

CTSB CTSK CTSL

2.84e-069114322952693
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

CRYBG2 SLC37A3 DGKQ PIGG TNRC6C BIRC6 CCDC142 FZD1 IGF2R ADAMTS7 PKD1 PDIA5 LTK TIMM22 NOTCH1

3.42e-0611051141535748872
Pubmed

NLRP3 inflammasomes are required for atherogenesis and activated by cholesterol crystals.

CTSB CTSL CTSV

4.05e-0610114320428172
Pubmed

Frontline Science: Multiple cathepsins promote inflammasome-independent, particle-induced cell death during NLRP3-dependent IL-1β activation.

CTSB CTSL CTSV

4.05e-0610114328087651
Pubmed

Cathepsin D in pancreatic acinar cells is implicated in cathepsin B and L degradation, but not in autophagic activity.

CTSB CTSL CTSV

5.55e-0611114326682926
Pubmed

Hnf1b haploinsufficiency differentially affects developmental target genes in a new renal cysts and diabetes mouse model.

CUBN SLC22A6 SLC12A3 PKD1

5.95e-0636114433737325
Pubmed

The genes of the lysosomal cysteine proteinases cathepsin B, H, L, and S map to different mouse chromosomes.

CTSB CTSL CTSV

7.38e-061211439096102
Pubmed

Comprehensive proteomic characterization of stem cell-derived extracellular matrices.

LGALS1 THBS3 LOXL2 LTBP2 CTSB

9.76e-0686114528327460
Pubmed

Acquisition of T regulatory function in cathepsin L-inhibited T cells by eye-derived CTLA-2alpha during inflammatory conditions.

CTSL CTSV

1.07e-052114219801522
Pubmed

Identification of procathepsin L (pCTS-L)-neutralizing monoclonal antibodies to treat potentially lethal sepsis.

CTSL CTSV

1.07e-052114236735789
Pubmed

Homeodomain-interacting protein kinase HIPK4 regulates phosphorylation of manchette protein RIMBP3 during spermiogenesis.

HIPK4 RIMBP3

1.07e-052114235931115
Pubmed

Cathepsin L promotes Vascular Intimal Hyperplasia after Arterial Injury.

CTSL CTSV

1.07e-052114228332696
Pubmed

Autophagic-lysosomal pathway is the main proteolytic system modified in the skeletal muscle of esophageal cancer patients.

CTSB CTSL

1.07e-052114224108784
Pubmed

Differential patterns of NOTCH1-4 receptor expression are markers of glioma cell differentiation.

NOTCH1 NOTCH4

1.07e-052114224305720
Pubmed

Impaired turnover of autophagolysosomes in cathepsin L deficiency.

CTSL CTSV

1.07e-052114220536383
Pubmed

Nuclear cysteine cathepsin variants in thyroid carcinoma cells.

CTSB CTSV

1.07e-052114220536394
Pubmed

Notch signaling in cancer.

NOTCH1 NOTCH4

1.07e-052114212496471
Pubmed

Lysosomal, cytoskeletal, and metabolic alterations in cardiomyopathy of cathepsin L knockout mice.

CTSL CTSV

1.07e-052114216636100
Pubmed

Cathepsin L Regulates Metabolic Networks Controlling Rapid Cell Growth and Proliferation.

CTSL CTSV

1.07e-052114231010818
Pubmed

Promiscuous processing of human alphabeta-protryptases by cathepsins L, B, and C.

CTSB CTSL

1.07e-052114221562164
Pubmed

Immunohistochemical staining of cathepsins B, L and stefin A in human hypophysis and pituitary adenomas.

CTSB CTSL

1.07e-052114215816632
Pubmed

Differential levels of cathepsin B and L in serum between young and aged healthy people and their association with matrix metalloproteinase 2.

CTSB CTSL

1.07e-052114225991043
Pubmed

Serum cathepsin levels in coronary artery ectasia.

CTSK CTSL

1.07e-052114220837372
Pubmed

Cystatin B, cathepsin L and D related to surrogate markers for cardiovascular disease in children.

CTSB CTSL

1.07e-052114229149174
Pubmed

Inhibition of Notch pathway attenuates the progression of human immunodeficiency virus-associated nephropathy.

NOTCH1 NOTCH4

1.07e-052114223389453
Pubmed

A variant of pulmonary alveolar microlithiasis in nackt mice.

CTSL CTSV

1.07e-052114212014504
Pubmed

Notch signaling: from the outside in.

NOTCH1 NOTCH4

1.07e-052114211112321
Pubmed

Mice that express enzymatically inactive cathepsin L exhibit abnormal spermatogenesis.

CTSL CTSV

1.07e-052114212533435
Pubmed

Thymosin beta4 induces angiogenesis through Notch signaling in endothelial cells.

NOTCH1 NOTCH4

1.07e-052114223749167
Pubmed

Loss of Cathepsin B and L Leads to Lysosomal Dysfunction, NPC-Like Cholesterol Sequestration and Accumulation of the Key Alzheimer's Proteins.

CTSB CTSL

1.07e-052114227902765
Pubmed

Cathepsin L was involved in vascular aging by mediating phenotypic transformation of vascular cells.

CTSL CTSV

1.07e-052114236206719
Pubmed

Sequence and expression of the cDNA for MEP (major excreted protein), a transformation-regulated secreted cathepsin.

CTSL CTSV

1.07e-05211423689328
Pubmed

Proteolytic processing of dynamin by cytoplasmic cathepsin L is a mechanism for proteinuric kidney disease.

CTSL CTSV

1.07e-052114217671649
Pubmed

Human cathepsin L rescues the neurodegeneration and lethality in cathepsin B/L double-deficient mice.

CTSB CTSL

1.07e-052114216913838
Pubmed

Contribution of cathepsin L to secretome composition and cleavage pattern of mouse embryonic fibroblasts.

CTSL CTSV

1.07e-052114221972973
Pubmed

Cathepsin L stabilizes the histone modification landscape on the Y chromosome and pericentromeric heterochromatin.

CTSL CTSV

1.07e-052114216705169
GeneFamilyCathepsins

CTSB CTSK CTSL CTSV

4.22e-0715784470
GeneFamilyReceptor Tyrosine Kinases|CD molecules

NTRK3 INSR TIE1 LTK

2.60e-0540784321
GeneFamilyProteases, serine

TMPRSS9 PRSS3 PRSS56 PRSS27

1.57e-0463784738
GeneFamilyC2 domain containing|Calpains

CAPN13 CAPN7

1.86e-0315782975
CoexpressionNABA_ECM_REGULATORS

PRSS3 F7 ADAMTS7 LOXL2 LOXL4 CTSB CTSK CTSL CTSV MASP2

8.65e-0823811310M3468
CoexpressionNABA_ECM_REGULATORS

PRSS3 F7 ADAMTS7 LOXL2 LOXL4 CTSB CTSK CTSL CTSV MASP2

1.01e-0724211310MM17062
CoexpressionHENDRICKS_SMARCA4_TARGETS_UP

HKDC1 LGALS1 LMNA LOXL2 CTSB

3.64e-06541135M15057
CoexpressionNABA_MATRISOME_HYPERPLASTIC_PANCREATIC_ISLETS

PRSS3 LGALS1 CTSL CTSV

4.55e-06261134MM17051
CoexpressionNAKAYA_B_CELL_FLUARIX_FLUVIRIN_AGE_18_50YO_7DY_DN

MRM2 DGKQ CUBN ZNF692 KIAA1614 KLHL20 FEM1B APOL5

4.21e-052941138M41112
ToppCellmLN-(2)_B_cell-(20)_B_cell_IgA_Plasma|mLN / shred on region, Cell_type, and subtype

PRSS3 SPAG4 KLK10 INSR LGALS1 PDIA5 CTNND2

7.68e-071971147a39b384ee9824a08c3b544a9c3c7f0f95f08d6a7
ToppCellmLN-B_cell-B_cell_IgA_Plasma|mLN / Region, Cell class and subclass

PRSS3 SPAG4 KLK10 INSR LGALS1 PDIA5 CTNND2

7.68e-07197114720822fce311326765b71337ce501ba44ea14f58f
ToppCell3'-GW_trimst-2|3' / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TMEM176B NTRK3 TSPYL2 LGALS1 LMNA PCDH11X CTSK

7.95e-071981147cf9861bc14737f2dc72e50222159e0180a6d3e5c
ToppCell367C-Myeloid-Dendritic-pDC|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

NAT8L SPAG4 TTC24 CUBN SLC12A3 LTK

4.12e-06164114695b800c78871354c859abaa832d778786ef7bcc0
ToppCellsevere-Myeloid-pDC|Myeloid / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs

NAT8L TTC24 SLC12A3 LTK CTSV NOTCH4

4.42e-061661146ae38850fde549b8dd6fb12f0ef80b428ade50485
ToppCell367C-Myeloid-Dendritic-pDC|Dendritic / Donor, Lineage, Cell class and subclass (all cells)

NAT8L SPAG4 TTC24 CUBN SLC12A3 LTK

5.07e-061701146fbb7019c6fba87326702b51f6819ea1af5f3a9b7
ToppCell3'-Broncho-tracheal-Immune_Myeloid-Myeloid_macrophage-elicited_macrophage-Monocyte-derived_macrophage-Monocyte-derived_macrophage_L.1.0.1.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

TMEM176B LGALS1 IGF2R RIMBP3C CTSB CTSL

5.24e-061711146b520d4d5620cac08315e4cbb7e796c5e9e233060
ToppCellControl-Myeloid-MoAM2,_CCL18|Control / Condition, Lineage and Cell class

LGALS1 THBS3 CD163L1 LTBP2 CTSB CTSK

5.79e-0617411464c64ff5666812fb4efa440ba4faeca51d916d68e
ToppCell5'-Parenchyma_lung-Immune_Myeloid-Myeloid_macrophage-alveolar_macrophage-Alveolar_macrophage_MT-positive-Alveolar_macrophage_MT-positive_L.1.0.1.3|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

TMEM121B LGALS1 LMNA CD163L1 CTSB CTSL

5.99e-061751146b227d4499274fb63b193d34de7f2d812e283e79d
ToppCell5'-Parenchyma_lung-Immune_Myeloid-Myeloid_macrophage-alveolar_macrophage-Alveolar_macrophage_MT-positive|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

TMEM121B LGALS1 LMNA CD163L1 CTSB CTSL

5.99e-061751146308ee4ef7b9ecea68efca011ef91aed0f1be0eca
ToppCellB_cells-pDCs|B_cells / Immune cells in Kidney/Urine in Lupus Nephritis

NAT8L DMXL2 SLC12A3 CTSB CTSV NOTCH4

6.18e-061761146ce757de9e09a225f3f96433f103f43619b0e0dda
ToppCellPND03-Immune-Immune_Myeloid-Monocytic-Macrophage-AM-AM_prolif|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

DMXL2 KLHL1 F7 WDHD1 CTSB CTSK

6.18e-061761146270d7908dbd84028958d257f94941dc685e20255
ToppCellControl-Myeloid-MoAM2,_CCL18|Myeloid / Condition, Lineage and Cell class

LGALS1 THBS3 CD163L1 LTBP2 CTSB CTSK

6.39e-061771146470f54fe2b21c7350ea471e02039461a3808f700
ToppCellHealthy/Control-pDC|World / Disease group and Cell class

NAT8L TTC24 SLC12A3 LTK CTNND2 NOTCH4

7.49e-06182114697e0eee10905f2cf2bebb09e474629fc224f4397
ToppCellBAL-Control-Myeloid-Macrophage|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

LGALS1 B3GNT8 CTNND2 CTSB CTSK CTSL

7.73e-0618311468e9d45c96b44558158e3d59613f64a73d5390c19
ToppCellBAL-Control-Myeloid-Macrophage-transitional_Macro-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

LGALS1 B3GNT8 CTNND2 CTSB CTSK CTSL

7.73e-0618311460408d991ddb639594b45d5cb2432dd29289167b1
ToppCellBAL-Control-Myeloid-Macrophage-transitional_Macro|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

LGALS1 B3GNT8 CTNND2 CTSB CTSK CTSL

7.73e-06183114679f05b8a967124d831b0baef137e30659f5917a7
ToppCellBAL-Control-Myeloid-Macrophage-transitional_Macro-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

LGALS1 B3GNT8 CTNND2 CTSB CTSK CTSL

7.97e-06184114692202e1cd0bba1ce4b061ebcb8a2af5bb590542a
ToppCellnormal_Lung-Endothelial_cells-Tumor_ECs|normal_Lung / Location, Cell class and cell subclass

INSR TIE1 LOXL2 FEV NALF2 NOTCH4

7.97e-0618411467ee98acda030366ac6cf3890a6d93fd0426712ed
ToppCellBAL-Control-Myeloid-Macrophage|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

LGALS1 B3GNT8 CTNND2 CTSB CTSK CTSL

7.97e-0618411467331535d469453a5264dcb0270a97f63d3b55201
ToppCelldroplet-Lung-18m-Hematologic-myeloid-alveolar_macrophage|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

DMXL2 F7 LMNA QDPR CTSK PCYOX1

7.97e-0618411468fa30789c9d583188667cf375d2218e392dd40bc
ToppCellBAL-Control-Myeloid-Macrophage-transitional_Macro|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

LGALS1 B3GNT8 CTNND2 CTSB CTSK CTSL

7.97e-061841146337e38a6b2b6770cc992d88b006829f194841b10
ToppCell3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.0.3|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

PRSS3 CRYBG2 KLK10 ITGB8 PRSS27 CTSV

8.22e-061851146f3fbc3096f85397a959cee17c3c4fcf2d511f3d5
ToppCelldroplet-Lung-immune-endo-depleted-3m-Myeloid-alveolar_macrophage|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DMXL2 F7 LMNA QDPR CTSK PCYOX1

8.22e-061851146afbb88325e4a81c15ac1d0a004e3e1f4ba2ee87b
ToppCelldroplet-Lung-18m-Hematologic-myeloid-alveolar_macrophage-alveolar_macrophage|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

DMXL2 F7 LMNA QDPR CTSK PCYOX1

8.22e-0618511464bee178ede12f56ba5f5bec44a03dc2a62c50137
ToppCelldroplet-Lung-nan-18m-Myeloid-alveolar_macrophage|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DMXL2 F7 LMNA QDPR CTSK PCYOX1

8.74e-061871146f0c6e53035b00772377c4d5f761b4d11026b911a
ToppCelldroplet-Lung-nan-18m-Myeloid-Alveolar_Macrophage|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DMXL2 F7 LMNA QDPR CTSK PCYOX1

8.74e-061871146f20e7a1751694390f535ffb27b97e887220f8695
ToppCellsaliva-Mild-Moderate_progression_d12-25-Myeloid-Dendritic-conventional_dendritic_cell|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)

HK1 TMEM176B LGALS1 FZD1 CTSB CTSL

9.01e-061881146e35104ca327c2d9eb6ffed658051f62f855a0a0e
ToppCell(2)_Fibroblasts-(20)_Fibro-1|World / Cell class and subclass of bone marrow stroma cells in homeostatis

NAT8L NTRK3 LGALS1 CLIP4 LMNA CTSK

9.01e-061881146409a7b69d02e87084ca955e3fe6c77230dee8861
ToppCellwk_15-18-Mesenchymal-Fibroblast-Airway_fibro|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

LGALS1 FZD1 LOXL2 PCDH11X LTBP2 CTSK

9.29e-0618911464f9608b84d135268a17455661870c46ae8554a24
ToppCellMyeloid-Myeloid-B_(Activated_Macrophage)|Myeloid / shred on cell class and cell subclass (v4)

DMXL2 F7 CTSB QDPR CTSK CTSL

9.86e-0619111467bf125249af1e8bb138ed4d999fdd74b03ab2447
ToppCellControl-pDC|Control / Disease condition and Cell class

NAT8L TTC24 TSPYL2 SLC12A3 LTK NOTCH4

9.86e-061911146543e1437a52d04436862dd1c27b4fae95c44fcc8
ToppCellsaliva-Mild-Moderate_progression_d12-25-Myeloid-Dendritic-conventional_dendritic_cell-DC_c2-CD1C|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)

HK1 TMEM176B LGALS1 FZD1 CTSB CTSL

9.86e-0619111465c0c44612b4cdbf89c0f1f219416374a7541f610
ToppCellControl-pDC-|Control / Disease condition and Cell class

NAT8L TTC24 TSPYL2 SLC12A3 LTK NOTCH4

9.86e-0619111461d7b0fae4d114d6db933c18b4eb2066ffa61356d
ToppCell5'-Airway_Nasal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.0.3|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

PRSS3 CRYBG2 KLK10 ITGB8 PRSS27 CTSV

9.86e-061911146fbd8d337b4444fba8527a614e4a8bfb516ce0f66
ToppCellNS-moderate-d_16-33-Epithelial-Squamous|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

PRSS3 CRYBG2 KLK10 ITGB8 PRSS27 CTSV

1.02e-051921146103496f428f59683ac3ae6147682c07c30663724
ToppCellAdult-Immune-alveolar_macrophage_(MARCO_positive)-D122|Adult / Lineage, Cell type, age group and donor

FKBP15 DMXL2 CLIP4 CD163L1 CTSB CTSL

1.05e-051931146cc1b6d3bf56e4a88f6fe23dd036a83cf5538c958
ToppCellMonocytes-M2-like_CD16+_macrophages|World / Immune cells in Kidney/Urine in Lupus Nephritis

TMEM176B FZD1 CD163L1 LTBP2 CTSB CTSL

1.11e-05195114610fa47bdcf6c9784ea930b75a5861e139421feed
ToppCellfacs-Bladder-nan-18m-Epithelial-bladder_cell|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TMEM176B LGALS1 LOXL2 CTSB CTSK CTSL

1.11e-0519511463e4f9ecfaa756386d816a26313b7229ec092d4e6
ToppCellControl-Myeloid-Macrophage|Control / Disease state, Lineage and Cell class

DMXL2 TMEM176B LGALS1 CD163L1 CTSB CTSL

1.14e-051961146e2c2a30fa3ee3034fbde5335be169e880dde622d
ToppCellPND01-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

LGALS1 NTN4 LMNA LOXL2 LTBP2 CTSL

1.14e-0519611469d7b631f24a19a7dc7a28f28525d4019fc8fcf8a
ToppCellParenchymal-10x5prime-Endothelial-Endothelia_vascular-VE_systemic_arterial|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

CUBN TIE1 PCDH11X FEV CTNND2 NOTCH4

1.18e-051971146ad4a3b5da2190be9495382a2952991e1de9f190d
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_no-steroids-Myeloid-Macrophage-macrophage,_alveolar-Macro_c1-C1QC|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

TMEM176B LGALS1 CD163L1 CTSB CTSK CTSL

1.18e-0519711461ded28732ea5d1f9ebca0b136575103540600ff1
ToppCellmoderate-Epithelial-Squamous|moderate / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

PRSS3 CRYBG2 KLK10 ITGB8 PRSS27 CTSV

1.18e-051971146ab3c90a5b643b45d0b83939c6304b11f567c5d78
ToppCellIPF-Myeloid-Macrophage|IPF / Disease state, Lineage and Cell class

DMXL2 LGALS1 CLIP4 CD163L1 CTSB CTSL

1.18e-051971146a2ffb33c7cad6be43cbb8ed9a91338923cc07db4
ToppCellmyeloid-Monocyte|myeloid / Lineage, cell class and subclass

DMXL2 ADGRG3 TMEM176B LGALS1 IGF2R NOTCH1

1.18e-0519711466acf059cee6ba6bdeacc089b090d72336790972a
ToppCelldroplet-Limb_Muscle-MUSCLE-30m-Mesenchymal-chondrocyte-like|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TMEM176B LGALS1 LOXL4 CTSK CTSL HDLBP

1.18e-051971146cfd4cc5fb8d7a60dd5c0d2a1a7bad7ba38c19d40
ToppCellPND14-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

LGALS1 FZD1 NTN4 LOXL2 LTBP2 CTSL

1.21e-051981146ce59ee3d970397eb62d6387699c6c6cd65457898
ToppCellPBMC-Mild-cDC_0|Mild / Compartment, Disease Groups and Clusters

DMXL2 TMEM176B CLIP4 IGF2R CTSB CTSL

1.21e-051981146fb873b7636bb1c7b119dd5b23d7a20f518e6c6da
ToppCell5'-GW_trimst-2-LargeIntestine-Mesenchymal-fibroblastic|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TMEM176B LGALS1 FZD1 LOXL2 PTCH2 CTSK

1.21e-05198114675d104eead681f6bf47c4dd24913cc768c9a1717
ToppCellParenchymal-10x3prime_v2-Stromal-Mesofibroblastic|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

NTRK3 THSD7B THBS3 PDIA5 LTBP2 CTSK

1.21e-0519811460cd930e374c2c48d1991b51c025f9801b22ecee7
ToppCellParenchymal-10x3prime_v2-Stromal-Mesofibroblastic-Mesothelia|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

NTRK3 THSD7B THBS3 PDIA5 LTBP2 CTSK

1.21e-051981146e0df6d6ff2a9c41d813f84a2a5ee7cb5f6fc3e30
ToppCell5'-GW_trimst-1.5-SmallIntestine-Mesenchymal-fibroblastic|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TMEM176B LGALS1 LOXL2 PTCH2 CTSK CTSL

1.25e-051991146edba1833ef5c4ca122d7c32f97670314e005f93b
ToppCellCOPD-Myeloid-Macrophage|COPD / Disease state, Lineage and Cell class

DMXL2 TMEM176B LMNA CD163L1 CTSB CTSL

1.25e-0519911464b9c53fb4f44190d2f6ad4d52b13be01ebe4955e
ToppCell5'-GW_trimst-2-SmallIntestine-Mesenchymal-fibroblastic|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TMEM176B LGALS1 ADAMTS7 LOXL2 LOXL4 CTSK

1.25e-051991146e78f661b40da34768469549b6e755d330be6bbd8
ToppCell10x_3'_v2v3-Non-neoplastic-Endothelial-Endothelial_mature-Endo_arterial-F|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

PRSS3 INSR TIE1 ADAMTS7 LOXL2 NOTCH4

1.25e-051991146463ba77dc4c85eebb343f29a42c7ac889b0497c9
ToppCelltumor_Lymph_Node_/_Brain-Fibroblasts-Myofibroblasts|Fibroblasts / Location, Cell class and cell subclass

LGALS1 FZD1 RCC1L LTBP2 CTSB CTSK

1.28e-052001146eabb7d4aa92ace7d970bcd3fae2c7cb5400a43b4
ToppCellCOVID-19-Myeloid|COVID-19 / Condition, Lineage and Cell class

FKBP15 DMXL2 TMEM176B LGALS1 CTSB CTSL

1.28e-0520011464c9e936b5e100c1a3ef10ea262febccf8226df9f
ToppCelldistal-Hematologic-EREG+_Dendritic-1|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

DMXL2 TMEM121B SLC12A3 CD163L1 CTSB CTSL

1.28e-0520011467809c74a2e52768854b66a135522138281bc4449
ToppCellControl-Epithelial_alveolar-AT_1-Differentiating_AT2|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

TSPYL2 CUBN ITGB8 CAPN13 PDIA5

2.83e-051381145611fe0fb284e12678f9c47a0bdbfc367a93c52b3
ToppCellkidney_cells-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_1_/_Segment_2|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

CUBN SLC22A6 CTSB CTSL PCYOX1

3.59e-05145114547a3bb973a508d3097213a2d86ad1ce697af9bae
ToppCellfacs-Marrow-KLS-18m-Myeloid-CD4+_macrophage|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CCDC142 FZD1 PKD1 CTNND2 NOTCH4

5.25e-0515711455d08ff0ba9d3df9cc30f13cab2d2b395ea6f3446
ToppCellLPS-IL1RA+antiTNF-Epithelial_alveolar-Mes-Like-AT1_Progenitor|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

EPM2A THSD7B NTN4 PDIA5 TIMM22

5.25e-051571145a93866f051472506f1468f379c0d5313e02c9731
ToppCellfacs-Marrow-KLS-18m-Myeloid-macrophage|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CCDC142 FZD1 PKD1 CTNND2 NOTCH4

5.25e-051571145ad9c9b7dfeee3ae46e7e593c51a0407df12195b4
ToppCellfacs-Brain_Non-Myeloid-Striatum_-18m-Neuronal-neuron|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SPAG4 KLK10 HIPK4 CCDC142

5.60e-058111441a22222f2b4ab30f7aa31820029c267a0f2190ec
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_1-Inh_L1-6_VIP_PENK|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

PRR23C PLA2G3 PRSS56 THSD7B CTSV

6.27e-051631145551b3788bcf494c6121e64ce5af72266de12a06b
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte-|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

DOK1 NTRK3 THSD7B FZD1 LTK

6.64e-0516511454f83ac71efc57be3668d8db1e62bad05dc6a5e2b
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

DOK1 NTRK3 THSD7B FZD1 LTK

6.64e-051651145cd8de98af8a1a8a6c81d71fae807cc07f319f4c9
ToppCellPND14-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-AEC|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ARMCX4 TIE1 PDIA5 NOTCH1 NOTCH4

6.83e-0516611457a45785a40b7425f97be67bab1c5ceb69b2bd85a
ToppCellPND14-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-AEC-AEC_mature|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ARMCX4 TIE1 PDIA5 NOTCH1 NOTCH4

6.83e-051661145bbd382812f8a84a5d99888de2d7cca3a8b5e4695
ToppCell367C-Myeloid-Dendritic-pDC|367C / Donor, Lineage, Cell class and subclass (all cells)

NAT8L SPAG4 TTC24 SLC12A3 LTK

7.03e-051671145650de8cd5df070639b8aa292aacead739cfdb02c
ToppCell10x5'-GI_small-bowel-Myeloid_Mac-Macrophage|GI_small-bowel / Manually curated celltypes from each tissue

DMXL2 KIAA1614 CD163L1 CTSB CTSL

7.23e-051681145d5b746d6083c2c8155a0ea345ea368bf6617d5ca
ToppCellE18.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-PMP-PMP_mature|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

FZD1 NTN4 ADAMTS7 MRNIP CTSK

7.43e-0516911457cb1b87be66a22fe5731bb1b55bc515920fe3e8b
ToppCellCOVID-19-Heart-CM_+_Macrophage|Heart / Disease (COVID-19 only), tissue and cell type

DMXL2 TG CD163L1 CTNND2 CTSB

7.64e-0517011454232fe937909f93d3736988c707b8f95ce993398
ToppCell3'-Child04-06-SmallIntestine-Mesenchymal-fibroblastic-mLTo|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

LGALS1 PCDH11X PTCH2 LTBP2 CTSK

7.64e-0517011457653f1205d4e62abe7e31b1d76f9bbd665e45667
ToppCell10x_3'_v2v3-Non-neoplastic-Myeloid-TAM-BDM-TAM-BDM_INF-C|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

SPAG4 TMEM176B LGALS1 CTSB CTSL

7.86e-0517111452b8dbc6fcd829d06f43b875db2bf81f8374428fa
ToppCellPND01-03-samps-Endothelial-Postnatal_endothelial-endothelial_cells_D|PND01-03-samps / Age Group, Lineage, Cell class and subclass

KLHL1 TIE1 IFT80 NOTCH1 NOTCH4

8.53e-051741145b4f3f5334803e5903bc496decf923f2e44f7fa3c
ToppCell3'_v3-blood-Mast-Mast_cells|blood / Manually curated celltypes from each tissue

TMPRSS9 PRSS3 ITGB8 DENND1B ZNF646

9.00e-051761145b9da3deaf62622d47eb30b6be7548253eee95597
ToppCellfacs-Trachea-24m-Endothelial-endothelial_cell_of_trachea-tracheal_endothelial_cell-tracheal_endothelial_cell_l54|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

NAT8L PRSS3 ADGRG3 PGC TIE1

9.00e-051761145460cb302c5b3d609c65b924e1d4e8ea057a68485
ToppCellPND14-Immune-Immune_Myeloid-Monocytic-Macrophage-AM-AM_mature|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

DMXL2 F7 TG CTSB CTSK

9.00e-051761145b0b87eebcf5c994386b39ca607e17f10e9d9de74
ToppCellwk_15-18-Epithelial-PNS-Schwann_precursor|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

TMPRSS9 PRSS56 CLIP4 PRSS27 CTSV

9.24e-0517711455357359e6c2161a37f39a6b3b78449f5cbc327d1
ToppCellE18.5-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-VSMC-VSMC_prolif|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

NTRK3 WDR54 LGALS1 LMNA LOXL2

9.24e-0517711454553ee8cd9c24db6511b09fe49ed11a89e7cde9e
ToppCellHealthy/Control-pDC|Healthy/Control / Disease group and Cell class

TTC24 SLC12A3 LTK CTNND2 NOTCH4

9.49e-051781145072b346c6bbd63f00efaceda486400a669b3ec48
ToppCellfacs-Brain_Non-Myeloid-Striatum-24m-Neuronal-neuron|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NAT8L TMPRSS9 KLHL1 HIPK4 PRRT3

9.49e-051781145a74e5a390cbeaca9de1fdb7b2a0e50783bd202dd
ToppCellfacs-Brain_Non-Myeloid-Striatum-24m-Neuronal-nan|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NAT8L TMPRSS9 KLHL1 HIPK4 PRRT3

9.49e-0517811451bddbc083c36657bd6910f7466126ab325e88176
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_no-steroids-Myeloid-Dendritic|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

LGALS1 CTSB CTSK CTSL

9.59e-059311446d91b52147fb68461b39223e52026f2a02dcda7f
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_no-steroids-Myeloid-Dendritic-conventional_dendritic_cell-DC_c2-CD1C|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

LGALS1 CTSB CTSK CTSL

9.59e-05931144d6409351d89f6289411bac4aff65322e91212e57
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_no-steroids-Myeloid-Dendritic-conventional_dendritic_cell|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

LGALS1 CTSB CTSK CTSL

9.59e-05931144d736a59d48fa0dc41afef67f1a1507105558e47c
ToppCell10x5'-lymph-node_spleen-Myeloid_Mac-Macrophage|lymph-node_spleen / Manually curated celltypes from each tissue

TMEM176B LGALS1 CTSB CTSK CTSL

9.75e-051791145b4430f633711cecf793e8e76e766a66ff1eff473
ToppCell10x5'-lymph-node_spleen-Myeloid_Mac-Intestinal_macrophages|lymph-node_spleen / Manually curated celltypes from each tissue

DMXL2 TMEM176B CD163L1 CTSB CTSL

1.00e-0418011457be7d7a6906fff6dbdecd9cb013d855aba4eda2a
ToppCellCOVID-19-kidney-PCT-S2|COVID-19 / Disease (COVID-19 only), tissue and cell type

INSR HKDC1 CUBN ITGB8 SLC22A6

1.00e-041801145358923e4228035a3e90e2957392089219e90dcd7
ToppCell10x5'-lymph-node_spleen-Myeloid_Mac-Cycling_Myeloid-Mac|lymph-node_spleen / Manually curated celltypes from each tissue

DMXL2 TMEM176B TMEM121B CD163L1 CTSL

1.00e-0418011454eea8366cdb82c356325ce88f09ad8b302c17a07
ToppCell10x_3'_v2v3-Non-neoplastic-Myeloid-Mast-Mast-E|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

TMPRSS9 HK1 WDHD1 ADAMTS7 MASP2

1.03e-041811145c35ca98c474e31917e0a53c092397e0d8d18b37c
ToppCellPND10-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-AEC-AEC_mature|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ARMCX4 TIE1 PDIA5 NOTCH1 NOTCH4

1.03e-0418111454d7793026373cbcf04b15c77f95f1025d07d4c00
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD|renal_cortex_nuclei / Celltypes from Cells and Nuclei per compartment and clinical group

INSR CUBN SLC12A3 TNRC6A LTBP2

1.03e-041811145c80ffa2ded5975a88e9a1a7d333196f95237bf0a
ToppCelltumor_Lung-Myeloid_cells-pDCs|tumor_Lung / Location, Cell class and cell subclass

NAT8L TTC24 IGF2R SLC12A3 LTK

1.03e-041811145c864ffeb9234b8c29754afc91c85a972889617f4
ToppCell5'-Parenchyma_lung-Immune_Myeloid-Myeloid_macrophage-alveolar_macrophage-Alveolar_macrophages-Alveolar_macrophages_L.1.6.1.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

FKBP15 DMXL2 TMEM176B CTSB CTSL

1.05e-0418211454234d0cc57b5266a5e03133c75c7918abe48465e
ToppCellcellseq-Mesenchymal-Chondrocytic-Mesenchymal_Airway/Vascular|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

NAT8L PRSS3 KIAA1614 LTBP2 CTSK

1.05e-041821145bb7de0c93d8f59f13c990e425139b9348ca8027e
ToppCellcellseq-Mesenchymal-Chondrocytic-Mesenchymal_Airway/Vascular-Chondrocyte|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

NAT8L PRSS3 KIAA1614 LTBP2 CTSK

1.05e-041821145507f095af4dff60f2c2b64d750477154084c3595
ToppCellcellseq-Mesenchymal-Chondrocytic|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

NAT8L PRSS3 KIAA1614 LTBP2 CTSK

1.05e-04182114588bd17c07bd8443a0ede4e9dc7bc9d1230b42211
ComputationalGenes in the cancer module 107.

KLK10 PGC CTSB CTSK CTSL

1.10e-0479655MODULE_107
ComputationalGenes in the cancer module 172.

KLK10 PGC CTSB CTSK CTSL

2.77e-0496655MODULE_172
Drugcarbohydrazide

LOXL2 LOXL4 CTSB CTSK CTSL

3.68e-08201115CID000073948
DrugLeupeptin hydrochloride

PRSS3 KLK10 CUBN TG PRSS27 CAPN7 CTSB CTSK CTSL CTSV HDLBP

1.10e-0727611111CID000003910
Drugbenzyloxycarbonyl-phenylalanylarginine-4-methylcoumaryl-7-amide

CTSB CTSK CTSL

4.50e-0741113ctd:C021159
Drugrelacatib

CTSB CTSK CTSV

1.12e-0651113CID006918602
DrugAC1NRA23

PRSS3 CUBN CTSB CTSK CTSL CTSV

1.53e-06731116CID005287657
DrugNSC272671

PRSS3 PGC TG CTSB CTSK CTSL CTSV HDLBP

2.24e-061741118CID000004742
Drugdiisopropylfluorophosphate

TMPRSS9 PRSS3 KLK10 AZU1 PLA2G3 PGC F7 PRSS27 PCYOX1 MASP2

3.95e-0632111110CID000005936
DrugSpiramycin [8025-81-8]; Up 200; 4.8uM; PC3; HT_HG-U133A

DOK1 KLK10 NTRK3 FZD1 DGLUCY ADAMTS7 LOXL2 MRNIP

6.05e-0619911183762_UP
Drugthallium

BIRC6 TG LOXL2 LOXL4

6.25e-06251114CID000105005
Drugcimaterol

CTSB CTSK CTSL CTSV

1.16e-05291114CID000002755
DrugAC1NBIRU

IGF2R CTSB CTSK CTSL CTSV

1.30e-05621115CID004468718
DrugE 64

PRSS3 CAPN7 CTSB CTSK CTSL CTSV HDLBP

1.42e-051611117CID000123985
DrugE64A

CTSB CTSK CTSL CTSV

1.52e-05311114CID000173548
DrugC01631

CTSB CTSK CTSL CTSV

1.52e-05311114CID000439539
Drugdesmedipham

CTSB CTSK CTSL CTSV

1.52e-05311114CID000024743
Drug3-Amino-5-Phenylpentane

CTSK CTSV

2.36e-0521112DB02869
DrugAC1L2O2K

CTSB CTSL

2.36e-0521112CID000125141
DrugAC1LAR7G

PRSS3 CTSB CTSL CTSV

4.71e-05411114CID000493598
DrugBana

PRSS3 TG CTSB CTSV

5.19e-05421114CID000009365
Drugquinoline-8-carboxamide

CTSK CTSL

7.04e-0531112CID000150664
DrugAC1L2T7Q

CTSB CTSL

7.04e-0531112CID000128119
DrugZpambn

CTSB CTSL

7.04e-0531112CID000192229
DrugL-2-amino-6-oxopimelate

PGC IGF2R CTSB

7.30e-05171113CID000194695
Druganthranilic acid

FOXRED1 TSPYL2 CTSB CTSL CTSV

7.54e-05891115CID000000227
DrugPC-PI

PRSS3 CTSB CTSL

8.72e-05181113CID000007693
Diseaseotitis media (biomarker_via_orthology)

CTSB CTSK CTSL CTSV

3.48e-07171054DOID:10754 (biomarker_via_orthology)
Diseasehepatocellular carcinoma (implicated_via_orthology)

INSR CTSB CTSL CTSV

2.84e-05491054DOID:684 (implicated_via_orthology)
Diseaseglucose metabolism disease (implicated_via_orthology)

HK1 INSR HKDC1

1.34e-04281053DOID:4194 (implicated_via_orthology)
DiseaseGlioblastoma

CTNND2 CTSB CTSK NOTCH1

1.85e-04791054C0017636
DiseaseGiant Cell Glioblastoma

CTNND2 CTSB CTSK NOTCH1

2.35e-04841054C0334588
DiseaseVisual Impairment

HK1 TSEN54

2.60e-0471052C3665347
Diseasetype 2 diabetes mellitus (is_implicated_in)

INSR F7 IGF2R LMNA PARL

3.73e-041711055DOID:9352 (is_implicated_in)
Diseasehemangiopericytoma (is_marker_for)

NOTCH1 NOTCH4

4.44e-0491052DOID:264 (is_marker_for)
DiseaseGlioblastoma Multiforme

CTNND2 CTSB CTSK NOTCH1

6.77e-041111054C1621958
Diseasestenosing tenosynovitis

KLHL1 LTBP2

8.09e-04121052EFO_0010822
Diseaseintracranial aneurysm (biomarker_via_orthology)

CTSB CTSK

9.54e-04131052DOID:10941 (biomarker_via_orthology)
DiseaseConnective Tissue Diseases

PKD1 NOTCH1

9.54e-04131052C0009782
Diseaseintracranial aneurysm (is_marker_for)

CTSB CTSK

1.11e-03141052DOID:10941 (is_marker_for)
DiseaseProteinuria

CUBN ADAMTS7

1.28e-03151052HP_0000093
Diseasetype 2 diabetes mellitus (is_marker_for)

F7 PARL CTSB CTSL

1.44e-031361054DOID:9352 (is_marker_for)
DiseaseMonogenic diabetes

INSR LMNA

1.46e-03161052C3888631
DiseaseNeoplastic Cell Transformation

PARG LOXL2 CTNND2 NOTCH1

1.56e-031391054C0007621
Diseasebreast carcinoma (is_marker_for)

FZD1 IGF2R PARL

1.70e-03661053DOID:3459 (is_marker_for)
DiseaseSclerocystic Ovaries

LMNA ADAMTS7 FSHR LTK

1.78e-031441054C1136382
DiseasePolycystic Ovary Syndrome

LMNA ADAMTS7 FSHR LTK

1.78e-031441054C0032460
DiseaseCongenital hernia of foramen of Morgagni

INSR IGF2R

2.06e-03191052C0265699
DiseaseCongenital hernia of foramen of Bochdalek

INSR IGF2R

2.06e-03191052C0265700
DiseaseParkinson's disease (implicated_via_orthology)

HIPK4 INSR SSTR5 PTCH2

2.43e-031571054DOID:14330 (implicated_via_orthology)
DiseaseCongenital diaphragmatic hernia

INSR IGF2R

2.52e-03211052C0235833
DiseaseLewy Body Disease

INSR IGF2R

2.77e-03221052C0752347
Diseasetooth agenesis

THSD7B NALF2

2.77e-03221052EFO_0005410
Diseaseage of onset of asthma

ITGB8 LTBP2 LTK

2.85e-03791053OBA_2001001
Diseasedilated cardiomyopathy (implicated_via_orthology)

LTBP2 CTSL CTSV

2.95e-03801053DOID:12930 (implicated_via_orthology)
DiseaseCarcinoma, Pancreatic Ductal

NOTCH1 NOTCH4

3.29e-03241052C0887833
Diseasenephrotic syndrome (biomarker_via_orthology)

CTSL CTSV

3.29e-03241052DOID:1184 (biomarker_via_orthology)
Diseasetype 1 diabetes mellitus (is_implicated_in)

F7 IGF2R NOTCH4

3.50e-03851053DOID:9744 (is_implicated_in)

Protein segments in the cluster

PeptideGeneStartEntry
CGSCWAFSSVGALEG

CTSK

136

P43235
CSSAAGAGAAGVSEW

BIRC6

41

Q9NR09
DQGSCGSCWAFGAVE

CTSB

101

P07858
GSCWAFSATGALEGQ

CTSV

136

O60911
ANAGCIAWEGGHGEF

FEV

61

Q99581
ACDAWAGGKAGSAVI

DGKQ

356

P52824
NVGSGSKGSDAACWA

ADGRG3

326

Q86Y34
SWDQGFCQALGSALG

CCDC142

366

Q17RM4
QQGGAADCWFLAALG

CAPN13

86

Q6MZZ7
CGVADGEGFLSIWQV

DMXL2

2821

Q8TDJ6
GWGNNDCSHSEDVGV

CD163L1

666

Q9NR16
NSGCTGGEASLWDCI

CD163L1

756

Q9NR16
DAILCVAGGWAGGNA

QDPR

81

P09417
FCGTTEFASGQWAGI

CLIP4

301

Q8N3C7
GEANGKDAESSGCWG

CTNND2

796

Q9UQB3
GSQVSGSCWTGAGAV

ARMCX4

1551

Q5H9R4
EFEDQACGGGSWAGA

ARMCX4

1661

Q5H9R4
AGGVDIGSWFCAGNE

ARMCX4

1941

Q5H9R4
QAGNWSECSTTCGLG

ADAMTS7

1416

Q9UKP4
TGCAVLNGEGHVFVW

RCC1L

346

Q96I51
GAWPEAGGQSATCEE

RIMBP3B

551

A6NNM3
GAWPEAGGQSATCEE

RIMBP3C

551

A6NJZ7
CSRGVQDSGGSEVAW

MRNIP

161

Q6NTE8
TEGGCSLGAQAGWRT

FAM201A

46

Q5SY85
CNAGVGRSTAAVCGW

EPM2A

266

O95278
AGQVVTIWAAGAGAT

LMNA

491

P02545
ESSLDQCGSNGWGVS

LOXL4

106

Q96JB6
QCGSNGWGVSDCSHS

LOXL4

111

Q96JB6
FTVGGSTSLNGQCEW

NOTCH1

2296

P46531
ANTIVCNSKDGGAWG

LGALS1

56

P09382
SGNDFCIWCEVGGHT

NTRK3

716

Q16288
EAGHGLWGETCTNAV

HIPK4

436

Q8NE63
GWALGGGAEFTTACD

ECHDC1

156

Q9NTX5
EEAGTSQAGWACGRT

KIAA1614

626

Q5VZ46
NEATLAACTSNGWGV

LOXL2

131

Q9Y4K0
IDGATALWCAAGAGH

FEM1B

86

Q9UK73
QEGAEGGQGCSEAWA

LTK

291

P29376
SCSDSGLWAVEGGNK

PCYOX1

241

Q9UHG3
NLSAVATGNWGCGAF

PARG

861

Q86W56
ACAVGSEGVIGWTQA

FKBP15

261

Q5T1M5
VVASPGSGAWEACSN

NALF2

231

O75949
DGQDACGSNSWTVVD

INSR

546

P06213
GWVQGADGLCSVDQG

PCDH11X

1281

Q9BZA7
TQWEASGFCVNGDVG

OVOS2

751

Q6IE36
CINTEWGAFGDDGSL

HK1

256

P19367
WGQSLAFSGAALGCS

GPR78

131

Q96P69
GWCVQEDFISGGSRS

ITGB8

66

P26012
ASWQAVTGGCGGIFQ

CUBN

1501

O60494
RAAGGGASWELCAGA

FZD1

11

Q9UP38
AWSIDGTQIAGACGN

IFT80

276

Q9P2H3
FAVGGWCSGDAISSV

KLHL20

321

Q9Y2M5
QVQKSGASGSWDCGL

DOK1

451

Q99704
WSGQSAGGCGNFQET

CAPN7

696

Q9Y6W3
FSESGCQGSGREVWG

CRYBG2

991

Q8N1P7
AGAWSAQIAALAGVG

FOXRED1

291

Q96CU9
TTQEDCCGSVGAFWG

LTBP2

571

Q14767
GIVSWGSMNCGEAGQ

MASP2

651

O00187
WQTGAGCDAAGFFTV

FSHR

436

P23945
AGVSNWGGYALACAL

DGLUCY

516

Q7Z3D6
GDSTETGGCQAWGAA

B3GNT8

86

Q7Z7M8
TGGCQAWGAAAATEI

B3GNT8

91

Q7Z7M8
ATVEAGTRCQVAGWG

AZU1

141

P20160
LAFLCGGSGDQAEWN

DENND1B

616

Q6P3S1
VVDSWQSAVCGAFAG

SLC25A26

176

Q70HW3
ANGTGATEPCTDGWI

SLC22A6

96

Q4U2R8
TQGLSCAWGAAVALG

PRRT3

601

Q5FWE3
VEWNGGVSGRASFCG

KLC1

546

Q07866
GQGTICWVDCGDAES

PDIA5

76

Q14554
STGQGLAALSEQGWC

PKD1

216

P98161
AGTACAIAGWGALFE

PRSS56

221

P0CW18
QDWACSVAGTSLGGE

PANK1

11

Q8TE04
VGFTGCAFGSAAIWQ

PARL

106

Q9H300
GSAVGSCLVSEGNSW

IGF2R

1136

P11717
TEAWGCAATQASNSG

TNRC6C

476

Q9HCJ0
GCSWESGRAENGVTG

TSEN54

276

Q7Z6J9
AAAASWGQASGPGSC

TMEM121B

451

Q9BXQ6
CINTEWGAFGDDGAL

HKDC1

256

Q2TB90
WGCTVVAAGLSGVAG

NTN4

11

Q9HB63
NVWEASGNRSGGVCD

NTN4

346

Q9HB63
GAWPEAGGQSATCEE

RIMBP3

551

Q9UFD9
IVSWGQGCATVGHFG

F7

421

P08709
WDCAQSQGSVGLAGV

PTCH2

416

Q9Y6C5
GTAGADDCWQGVNGS

SHROOM1

446

Q2M3G4
LVAGGCAGVLAWAVA

SLC25A47

221

Q6Q0C1
VFADVQEGGTCNASW

SSTR5

176

P35346
CCGEVQSGTFQGAWL

NOTCH4

1596

Q99466
TLWCGVGDSAGNSSE

PLA2G3

156

Q9NZ20
NWQTACGAATVRGGA

SPAG4

86

Q9NPE6
SGCAFWAGSVVIAAG

TMEM176B

96

Q3YBM2
GSCWAFSATGALEGQ

CTSL

136

P07711
GGINWSEIEAAGFCV

APOL5

216

Q9BWW9
GGEGALETCSAVGWA

TSPYL2

141

Q9H2G4
GQWQACEGLGAAAAR

TTC24

351

A2A3L6
EFLIGGQASGWCSEG

PGC

256

P20142
GQASGWCSEGCQAIV

PGC

261

P20142
GVVFGLWSACASVGN

SLC37A3

176

Q8NCC5
GSHFCGGSLIAEQWV

PRSS27

56

Q9BQR3
SGFWECRVSTSGGQD

TIE1

421

P35590
EAICLGQGWAAAATS

WDHD1

536

O75717
NSSVGDLGVGGCSLW

nan

36

Q7L0L9
AVTGWQAGAAHTCSD

ZNF646

811

O15015
FLAGIVSWGIGCAEA

TMPRSS9

401

Q7Z410
NDTVTPGWGACEGLA

SLC12A3

406

P55017
GFGESLKAGSSWQCD

NUP153

651

P49790
VGWAGNGNVCGTDTD

THBS3

446

P49746
VLDCGAAPGAWSQVA

MRM2

76

Q9UI43
GSHFCGGSLISEQWV

PRSS3

101

P35030
AAGTECLISGWGNTL

PRSS3

191

P35030
CLISGWGNTLSFGAD

PRSS3

196

P35030
DWKNSVISGCITGGA

TIMM22

151

Q9Y584
AVGGDESTAGWAQGC

ZNF526

261

Q8TF50
AACLESAQEPSGAWG

HDLBP

51

Q00341
ALNATIGWNGEATCG

THSD7B

681

Q9C0I4
SHSACTWQGGALIAG

LCMT2

536

O60294
DGATAAWQDGPGCDV

PIGG

616

Q5H8A4
CSGAQGDWSAGLEVD

PRR23C

111

Q6ZRP0
DGRSCWCVGANGSEV

TG

66

P01266
KGSNCQGGWEDDSAA

TNRC6A

796

Q8NDV7
RNVEGGSGVTDCWAC

AVPR2

181

P30518
QDGGLVWECSAGHTF

ZNF692

106

Q9BU19
IAASGHFICVGTWSG

WDR54

126

Q9H977
GCLQQDGSGSFEHWG

KLHL1

36

Q9NR64
GDQCQVAGWGTTAAR

KLK10

166

O43240
GSCFWVAVLDGNVVG

NAT8L

181

Q8N9F0