Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionL-glutamine, sodium:proton antiporter activity

SLC38A5 SLC38A3

2.69e-0521042GO:0140830
GeneOntologyMolecularFunctionhigh voltage-gated calcium channel activity

CACNA1C CACNA1D CACNA1S

4.79e-05141043GO:0008331
GeneOntologyMolecularFunctionL-asparagine transmembrane transporter activity

SLC38A5 SLC38A3

1.60e-0441042GO:0015182
GeneOntologyMolecularFunctionvoltage-gated calcium channel activity involved in cardiac muscle cell action potential

CACNA1C CACNA1D

2.66e-0451042GO:0086007
GeneOntologyMolecularFunctionL-histidine transmembrane transporter activity

SLC38A5 SLC38A3

2.66e-0451042GO:0005290
GeneOntologyMolecularFunctionamino acid:monoatomic cation antiporter activity

SLC38A5 SLC38A3

2.66e-0451042GO:0140848
GeneOntologyMolecularFunctionfibroblast growth factor binding

RPS2 ITGB3 FGFR3

3.67e-04271043GO:0017134
GeneOntologyMolecularFunctionfatty acyl-CoA hydrolase activity

ACOT1 ACOT6 ACOT2

3.67e-04271043GO:0047617
GeneOntologyMolecularFunctionneuregulin binding

ERBB3 ITGB3

3.98e-0461042GO:0038132
GeneOntologyMolecularFunctionacyl-CoA hydrolase activity

ACOT1 ACOT6 ACOT2

4.09e-04281043GO:0016289
GeneOntologyMolecularFunctionL-glutamine transmembrane transporter activity

SLC38A5 SLC38A3

9.44e-0491042GO:0015186
GeneOntologyBiologicalProcessasparagine transmembrane transport

SLC38A5 SLC38A3

2.42e-0521022GO:1903713
GeneOntologyBiologicalProcesscellular response to interleukin-4

RPS2 PARP14 SHPK IL4R

3.66e-05381024GO:0071353
GeneOntologyBiologicalProcessresponse to interleukin-4

RPS2 PARP14 SHPK IL4R

4.96e-05411024GO:0070670
GeneOntologyBiologicalProcesslong-chain fatty-acyl-CoA catabolic process

ACOT1 ACOT2

7.24e-0531022GO:0036116
GeneOntologyBiologicalProcesssulfur compound catabolic process

ACOT1 IDUA GUSB ACOT2

1.37e-04531024GO:0044273
GeneOntologyBiologicalProcessactomyosin contractile ring assembly actin filament organization

PLEC IQGAP3

1.44e-0441022GO:2000689
GeneOntologyBiologicalProcessnegative regulation of mesenchymal cell apoptotic process involved in metanephros development

WT1 PAX8

1.44e-0441022GO:1900212
GeneOntologyBiologicalProcessregulation of mesenchymal cell apoptotic process involved in metanephros development

WT1 PAX8

1.44e-0441022GO:1900211
GeneOntologyBiologicalProcessmesenchymal cell apoptotic process involved in metanephros development

WT1 PAX8

1.44e-0441022GO:1900200
GeneOntologyBiologicalProcessasparagine transport

SLC38A5 SLC38A3

1.44e-0441022GO:0006867
GeneOntologyBiologicalProcessdetection of mechanical stimulus involved in sensory perception of sound

ADGRV1 STRC STRCP1

1.94e-04231023GO:0050910
GeneOntologyBiologicalProcessamide transport

CACNA1C CACNA1D PCLO SLC38A5 ADCY5 PTPRN PAX8 ABCC8 SLC38A3

2.38e-044201029GO:0042886
GeneOntologyBiologicalProcessL-glutamine import across plasma membrane

SLC38A5 SLC38A3

2.40e-0451022GO:1903803
GeneOntologyBiologicalProcesspositive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel

CACNA1C CACNA1D

2.40e-0451022GO:1904879
GeneOntologyBiologicalProcessglucose homeostasis

CACNA1C CACNA1D ADCY5 RAB34 PTPRJ PTPRN ABCC8 BACE2

2.76e-043381028GO:0042593
GeneOntologyBiologicalProcesscarbohydrate homeostasis

CACNA1C CACNA1D ADCY5 RAB34 PTPRJ PTPRN ABCC8 BACE2

2.81e-043391028GO:0033500
GeneOntologyBiologicalProcessvascular process in circulatory system

CACNA1C SLC38A5 PTPRJ ABCC8 SLC2A13 PLEC SLC38A3 SOD3

3.10e-043441028GO:0003018
GeneOntologyBiologicalProcessL-histidine transmembrane transport

SLC38A5 SLC38A3

3.59e-0461022GO:0089709
GeneOntologyCellularComponentL-type voltage-gated calcium channel complex

CACNA1C CACNA1D CACNA1S

2.47e-05121033GO:1990454
HumanPhenoAbdominal distention

COL11A2 WT1 DUX4 IDUA FREM2 PAX8 GUSB FGFR3 PLEC

7.45e-06155469HP:0003270
MousePhenoimpaired hearing

CACNA1D COL11A2 TMEM43 ADGRV1 IDUA PAX8 GUSB FGFR3 STRC STRCP1

8.59e-072238410MP:0006325
MousePhenoabnormal cochlear hair cell physiology

CACNA1D ADGRV1 PAX8 STRC STRCP1

3.87e-0640845MP:0004432
MousePhenoabnormal hair cell physiology

CACNA1D ADGRV1 PAX8 STRC STRCP1

1.08e-0549845MP:0003879
MousePhenoabnormal cochlear labyrinth morphology

CACNA1D COL11A2 TMEM43 ADGRV1 IDUA PAX8 FGFR3 STRC STRCP1

1.13e-05235849MP:0004426
MousePhenoabnormal scala media morphology

CACNA1D COL11A2 TMEM43 ADGRV1 IDUA PAX8 FGFR3 STRC STRCP1

1.13e-05235849MP:0003169
MousePhenoabnormal cochlea morphology

CACNA1D COL11A2 TMEM43 ADGRV1 IDUA PAX8 FGFR3 STRC STRCP1

1.74e-05248849MP:0000031
MousePhenoabnormal cochlear outer hair cell physiology

CACNA1D ADGRV1 STRC STRCP1

2.23e-0528844MP:0004434
MousePhenoabnormal membranous labyrinth morphology

CACNA1D COL11A2 TMEM43 ADGRV1 IDUA PAX8 FGFR3 STRC STRCP1

2.69e-05262849MP:0000035
MousePhenoabnormal cochlear hair cell morphology

CACNA1D TMEM43 ADGRV1 IDUA PAX8 FGFR3 STRC STRCP1

2.82e-05202848MP:0002622
MousePhenoabnormal cochlear sensory epithelium morphology

CACNA1D TMEM43 ADGRV1 IDUA PAX8 FGFR3 STRC STRCP1

3.36e-05207848MP:0003308
MousePhenoabnormal organ of Corti morphology

CACNA1D TMEM43 ADGRV1 IDUA PAX8 FGFR3 STRC STRCP1

3.59e-05209848MP:0000042
MousePhenoabnormal hair cell morphology

CACNA1D TMEM43 ADGRV1 IDUA PAX8 FGFR3 STRC STRCP1

4.25e-05214848MP:0000045
MousePhenoabnormal outer hair cell stereociliary bundle morphology

CACNA1D ADGRV1 PAX8 STRC STRCP1

5.38e-0568845MP:0004527
MousePhenodeafness

CACNA1D ADGRV1 IDUA PAX8 GUSB FGFR3

6.88e-05116846MP:0001967
MousePhenosensorineural hearing loss

CACNA1D COL11A2 IDUA FGFR3

6.89e-0537844MP:0004740
MousePhenoabnormal sensory neuron physiology

CACNA1D ADGRV1 PAX8 STRC STRCP1

7.09e-0572845MP:0010055
MousePhenoabnormal mechanoreceptor morphology

CACNA1D TMEM43 ADGRV1 IDUA PAX8 FGFR3 STRC STRCP1

7.29e-05231848MP:0000972
MousePhenosensorineural hearing impairment

CACNA1D COL11A2 IDUA FGFR3

7.66e-0538844MP:0006329
MousePhenoabnormal inner ear morphology

CACNA1D COL11A2 TMEM43 ADGRV1 IDUA PAX8 FGFR3 STRC STRCP1

8.30e-05303849MP:0000026
MousePhenoabsent distortion product otoacoustic emissions

CACNA1D ADGRV1 STRC STRCP1

1.04e-0441844MP:0004737
MousePhenoabnormal face size

IDUA FREM2 GUSB FGFR3

1.14e-0442844MP:0030063
MousePhenoabnormal organ of Corti supporting cell morphology

TMEM43 ADGRV1 PAX8 FGFR3

1.37e-0444844MP:0004300
MousePhenoabnormal somatic nervous system physiology

CACNA1D ADGRV1 PAX8 STRC STRCP1

1.40e-0483845MP:0005423
MousePhenoabnormal cochlear hair cell stereociliary bundle morphology

CACNA1D ADGRV1 PAX8 STRC STRCP1

2.15e-0491845MP:0004521
MousePhenoabnormal pillar cell morphology

ADGRV1 PAX8 FGFR3

2.22e-0420843MP:0003825
MousePhenoabnormal cochlear sensory neuron innervation pattern

CACNA1D PAX8 FGFR3

2.97e-0422843MP:0014489
MousePhenoabnormal cochlear outer hair cell morphology

CACNA1D ADGRV1 PAX8 FGFR3 STRC STRCP1

3.85e-04159846MP:0004399
MousePhenoabnormal hearing physiology

CACNA1D COL11A2 TMCO6 TMEM43 ADGRV1 RRBP1 IDUA PAX8 GUSB FGFR3 STRC STRCP1

4.39e-046438412MP:0001963
MousePhenoabnormal ear morphology

CACNA1D COL11A2 TMEM43 ADGRV1 IDUA FREM2 PAX8 FGFR3 STRC STRCP1

4.99e-044708410MP:0002102
MousePhenoincreased urine glycosaminoglycan level

IDUA GUSB

5.27e-046842MP:0011473
MousePhenoabnormal urine glycosaminoglycan level

IDUA GUSB

5.27e-046842MP:0011472
MousePhenoincreased or absent threshold for auditory brainstem response

CACNA1D COL11A2 TMEM43 ADGRV1 IDUA PAX8 FGFR3

5.37e-04236847MP:0011967
MousePhenoabnormal calcium ion homeostasis

CACNA1C CACNA1D CACNA1S KDM4C TMCO6 ITGB3 BCAR3 BACE2 LONRF2

6.98e-04404849MP:0004231
MousePhenoenlarged interparietal bone

CACNA1S FGFR3

7.35e-047842MP:0004386
MousePhenoincreased transforming growth factor beta level

ITGB3 IL4R

7.35e-047842MP:0008837
MousePhenoabnormal inner hair cell synaptic ribbon morphology

CACNA1D PAX8

7.35e-047842MP:0004562
MousePhenoabnormal cochlear IHC efferent innervation pattern

CACNA1D PAX8

7.35e-047842MP:0004633
MousePhenoabnormal ear physiology

CACNA1D COL11A2 TMCO6 TMEM43 ADGRV1 RRBP1 IDUA PAX8 GUSB FGFR3 STRC STRCP1

7.60e-046848412MP:0003878
MousePhenoabnormal hearing electrophysiology

CACNA1D COL11A2 TMCO6 TMEM43 ADGRV1 RRBP1 IDUA PAX8 FGFR3 STRC STRCP1

8.25e-045948411MP:0006335
DomainVDCC_L_a1su

CACNA1C CACNA1D CACNA1S

6.12e-0741013IPR005446
DomainBAAT_C

ACOT1 ACOT6 ACOT2

1.52e-0651013IPR014940
DomainBAAT_C

ACOT1 ACOT6 ACOT2

1.52e-0651013PF08840
DomainVDCC_a1su_IQ

CACNA1C CACNA1D CACNA1S

5.29e-0671013IPR014873
DomainGPHH

CACNA1C CACNA1D CACNA1S

5.29e-0671013PF16905
DomainGPHH_dom

CACNA1C CACNA1D CACNA1S

5.29e-0671013IPR031649
DomainCa_chan_IQ

CACNA1C CACNA1D CACNA1S

5.29e-0671013SM01062
DomainCa_chan_IQ

CACNA1C CACNA1D CACNA1S

5.29e-0671013PF08763
DomainVDCCAlpha1

CACNA1C CACNA1D CACNA1S

1.79e-05101013IPR002077
DomainVWFA

COL7A1 VWA1 ITGB3 ITGB7 HMCN2

8.21e-05821015PS50234
DomainCAC1F_C

CACNA1C CACNA1D

8.66e-0531012IPR031688
DomainCAC1F_C

CACNA1C CACNA1D

8.66e-0531012PF16885
DomainVWA

COL7A1 VWA1 ITGB3 ITGB7 HMCN2

9.21e-05841015SM00327
DomainBile_Hydr_Trans

ACOT1 ACOT2

1.73e-0441012PF04775
DomainThio_Ohase/aa_AcTrfase

ACOT1 ACOT2

1.73e-0441012IPR006862
DomainAcyl-CoA_thioEstase_long-chain

ACOT1 ACOT2

1.73e-0441012IPR016662
DomainVWF_A

COL7A1 VWA1 ITGB3 ITGB7 HMCN2

2.00e-04991015IPR002035
DomainIntegrin_bsu_cyt_dom

ITGB3 ITGB7

4.28e-0461012IPR014836
DomainIntegrin_b_cyt

ITGB3 ITGB7

4.28e-0461012SM01241
DomainIntegrin_b_cyt

ITGB3 ITGB7

4.28e-0461012PF08725
DomainFN3

COL7A1 VWA1 DSCAML1 PTPRJ ROBO3 IL4R

5.07e-041851016SM00060
DomainIntegrin_bsu_tail

ITGB3 ITGB7

5.97e-0471012IPR012896
DomainIntegrin_B_tail

ITGB3 ITGB7

5.97e-0471012SM01242
DomainIntegrin_B_tail

ITGB3 ITGB7

5.97e-0471012PF07965
Domain-

COL7A1 VWA1 ITGB3 ITGB7

6.93e-047410143.40.50.410
DomainFN3

COL7A1 VWA1 DSCAML1 PTPRJ ROBO3 IL4R

7.43e-041991016PS50853
DomainCalx_beta

ADGRV1 FREM2

7.94e-0481012SM00237
DomainIntegrin_beta

ITGB3 ITGB7

7.94e-0481012PF00362
DomainINB

ITGB3 ITGB7

7.94e-0481012SM00187
DomainIntegrin_bsu_VWA

ITGB3 ITGB7

7.94e-0481012IPR002369
DomainFN3_dom

COL7A1 VWA1 DSCAML1 PTPRJ ROBO3 IL4R

9.58e-042091016IPR003961
DomainCalx_beta

ADGRV1 FREM2

1.02e-0391012IPR003644
DomainIntegrin_bsu

ITGB3 ITGB7

1.02e-0391012IPR015812
DomainIntegin_beta_N

ITGB3 ITGB7

1.02e-0391012IPR033760
DomainINTEGRIN_BETA

ITGB3 ITGB7

1.02e-0391012PS00243
DomainPSI_integrin

ITGB3 ITGB7

1.02e-0391012PF17205
DomainCalx-beta

ADGRV1 FREM2

1.02e-0391012PF03160
DomainIg-like_fold

COL7A1 VWA1 DSCAML1 IGSF10 HMCN2 PTPRJ FGFR3 ADGRF3 FCRL5 ROBO3 IL4R

1.51e-0370610111IPR013783
DomainIGc2

DSCAML1 IGSF10 HMCN2 FGFR3 FCRL5 ROBO3

1.74e-032351016SM00408
DomainIg_sub2

DSCAML1 IGSF10 HMCN2 FGFR3 FCRL5 ROBO3

1.74e-032351016IPR003598
Domainfn3

COL7A1 VWA1 DSCAML1 PTPRJ ROBO3

1.87e-031621015PF00041
DomainPSI

ITGB3 ITGB7 SLC2A13

1.97e-03461013SM00423
DomainChannel_four-helix_dom

CACNA1C CACNA1D CACNA1S

3.63e-03571013IPR027359
Domain-

CACNA1C CACNA1D CACNA1S

3.63e-035710131.20.120.350
DomainIg_I-set

DSCAML1 IGSF10 HMCN2 FGFR3 ROBO3

3.72e-031901015IPR013098
DomainI-set

DSCAML1 IGSF10 HMCN2 FGFR3 ROBO3

3.72e-031901015PF07679
DomainAa_trans

SLC38A5 SLC38A3

3.73e-03171012PF01490
DomainAA_transpt_TM

SLC38A5 SLC38A3

3.73e-03171012IPR013057
PathwayKEGG_MEDICUS_VARIANT_SCRAPIE_CONFORMATION_PRPSC_TO_VGCC_CA2_APOPTOTIC_PATHWAY

CACNA1C CACNA1D CACNA1S

2.86e-066753M47762
PathwayKEGG_DILATED_CARDIOMYOPATHY

CACNA1C CACNA1D CACNA1S ITGB3 ADCY5 ITGB7

8.09e-0690756M835
PathwayKEGG_ARRHYTHMOGENIC_RIGHT_VENTRICULAR_CARDIOMYOPATHY_ARVC

CACNA1C CACNA1D CACNA1S ITGB3 ITGB7

4.51e-0574755M16376
PathwayWP_ARRHYTHMOGENIC_RIGHT_VENTRICULAR_CARDIOMYOPATHY

CACNA1C CACNA1D CACNA1S ITGB3 ITGB7

4.51e-0574755M39462
PathwayKEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_ABETA_TO_VGCC_CA2_APOPTOTIC_PATHWAY_N01004

CACNA1C CACNA1D CACNA1S

5.05e-0514753M47692
PathwayKEGG_HYPERTROPHIC_CARDIOMYOPATHY_HCM

CACNA1C CACNA1D CACNA1S ITGB3 ITGB7

7.83e-0583755M8728
PathwayKEGG_MEDICUS_REFERENCE_VGCC_CA2_APOPTOTIC_PATHWAY

CACNA1C CACNA1D CACNA1S

2.37e-0423753M47666
PathwayKEGG_MEDICUS_REFERENCE_CA2_ENTRY_VOLTAGE_GATED_CA2_CHANNEL

CACNA1C CACNA1D CACNA1S

3.06e-0425753M47948
PathwayREACTOME_REGULATION_OF_INSULIN_SECRETION

CACNA1C CACNA1D ADCY5 ABCC8

3.07e-0461754MM15071
PathwayWP_7OXOC_AND_7BETAHC_PATHWAYS

ACOT1 ACOT6 ACOT2

3.86e-0427753M40054
PathwayREACTOME_ADRENALINE_NORADRENALINE_INHIBITS_INSULIN_SECRETION

CACNA1C CACNA1D ADCY5

4.31e-0428753M10679
PathwayKEGG_MEDICUS_REFERENCE_HEPARAN_SULFATE_DEGRADATION

IDUA GUSB

5.76e-047752M47608
PathwayREACTOME_INTEGRATION_OF_ENERGY_METABOLISM

CACNA1C CACNA1D ADCY5 ABCC8

5.78e-0472754MM14631
Pubmed

Nucleotide sequence of the partially deleted D4Z4 locus in a patient with FSHD identifies a putative gene within each 3.3 kb element.

DUX4L9 DUX4L2 DUX4 DUX4L5 DUX4L6 DUX4L3 DUX4L4 DUX4L7

3.78e-1812110810433963
Pubmed

Evolutionary conservation of a coding function for D4Z4, the tandem DNA repeat mutated in facioscapulohumeral muscular dystrophy.

DUX4L9 DUX4L2 DUX4 DUX4L5 DUX4L6 DUX4L3 DUX4L4 DUX4L7

9.81e-1813110817668377
Pubmed

The DUX4 gene at the FSHD1A locus encodes a pro-apoptotic protein.

DUX4L2 DUX4 DUX4L5 DUX4L6 DUX4L3 DUX4L4 DUX4L7

2.08e-178110717588759
Pubmed

DUX4, a candidate gene of facioscapulohumeral muscular dystrophy, encodes a transcriptional activator of PITX1.

DUX4L2 DUX4 DUX4L5 DUX4L6 DUX4L3 DUX4L4 DUX4L7

3.10e-1610110717984056
Pubmed

Characterization of a tandemly repeated 3.3-kb KpnI unit in the facioscapulohumeral muscular dystrophy (FSHD) gene region on chromosome 4q35.

DUX4L2 DUX4 DUX4L5 DUX4L6 DUX4L3 DUX4L4 DUX4L7

4.41e-151311077739628
Pubmed

Active genes in junk DNA? Characterization of DUX genes embedded within 3.3 kb repeated elements.

DUX4L2 DUX4 DUX4L5 DUX4L6 DUX4L3 DUX4L4 DUX4L7

4.94e-1417110711245978
Pubmed

Impairment of hippocampal gamma-frequency oscillations in vitro in mice overexpressing human amyloid precursor protein (APP).

CACNA1C CACNA1D CACNA1S

3.08e-083110317767505
Pubmed

Molecular diversity of L-type calcium channels. Evidence for alternative splicing of the transcripts of three non-allelic genes.

CACNA1C CACNA1D CACNA1S

3.08e-08311032173707
Pubmed

Angiotensin II suppresses long-term depression in the lateral amygdala of mice via L-type calcium channels.

CACNA1C CACNA1D CACNA1S

3.08e-083110317289261
Pubmed

Mechanism of shortened bones in mucopolysaccharidosis VII.

IDUA GUSB FGFR3

3.08e-083110319375967
Pubmed

Beta-adrenergic-regulated phosphorylation of the skeletal muscle Ca(V)1.1 channel in the fight-or-flight response.

CACNA1C CACNA1D CACNA1S

1.23e-074110320937870
Pubmed

Expression profiling of immature thymocytes revealed a novel homeobox gene that regulates double-negative thymocyte development.

DUX4L9 DUX4L2 DUX4L4

1.23e-074110317911620
Pubmed

The homeobox transcription factor DUXBL controls exit from totipotency.

DUX4L9 DUX4L2 DUX4L4

1.23e-074110338509386
Pubmed

Characterization of genomic structures and expression profiles of three tandem repeats of a mouse double homeobox gene: Duxbl.

DUX4L9 DUX4L2 DUX4L4

3.06e-075110320063414
Pubmed

Analysis of the mouse and human acyl-CoA thioesterase (ACOT) gene clusters shows that convergent, functional evolution results in a reduced number of human peroxisomal ACOTs.

ACOT1 ACOT6 ACOT2

3.06e-075110316940157
Pubmed

Structural basis for endosomal trafficking of diverse transmembrane cargos by PX-FERM proteins.

ERBB3 ADGRV1 ITGB3 ITGB7 FCRL5 IL4R

8.66e-07101110623382219
Pubmed

The transcription factor Duxbl mediates elimination of pre-T cells that fail β-selection.

DUX4L9 DUX4L2 DUX4L4

1.07e-067110330765463
Pubmed

Enhanced expression of L-type Cav1.3 calcium channels in murine embryonic hearts from Cav1.2-deficient mice.

CACNA1C CACNA1D CACNA1S

1.07e-067110312900400
Pubmed

A revised nomenclature for mammalian acyl-CoA thioesterases/hydrolases.

ACOT1 ACOT6 ACOT2

2.55e-069110316103133
Pubmed

Temporal expression of calcium channel subunits in satellite cells and bone marrow mesenchymal cells.

CACNA1C CACNA1S

9.91e-062110225277766
Pubmed

A single nucleotide deletion in the skeletal muscle-specific calcium channel transcript of muscular dysgenesis (mdg) mice.

CACNA1C CACNA1S

9.91e-06211021281468
Pubmed

Different roles attributed to Cav1 channel subtypes in spontaneous action potential firing and fine tuning of exocytosis in mouse chromaffin cells.

CACNA1C CACNA1D

9.91e-062110221054386
Pubmed

Expression and function of glutamine transporters SN1 (SNAT3) and SN2 (SNAT5) in retinal Müller cells.

SLC38A5 SLC38A3

9.91e-062110216249471
Pubmed

An improved targeted cAMP sensor to study the regulation of adenylyl cyclase 8 by Ca2+ entry through voltage-gated channels.

CACNA1C CACNA1D

9.91e-062110224086669
Pubmed

Differential zinc permeation and blockade of L-type Ca2+ channel isoforms Cav1.2 and Cav1.3.

CACNA1C CACNA1D

9.91e-062110226049024
Pubmed

Acyl-CoA thioesterases belong to a novel gene family of peroxisome proliferator-regulated enzymes involved in lipid metabolism.

ACOT1 ACOT2

9.91e-062110211330065
Pubmed

Genetic polymorphisms of L-type calcium channel alpha1C and alpha1D subunit genes are associated with sensitivity to the antihypertensive effects of L-type dihydropyridine calcium-channel blockers.

CACNA1C CACNA1D

9.91e-062110219225208
Pubmed

Ca1.2 and CaV1.3 neuronal L-type calcium channels: differential targeting and signaling to pCREB.

CACNA1C CACNA1D

9.91e-062110216706838
Pubmed

Dual-vector gene therapy restores cochlear amplification and auditory sensitivity in a mouse model of DFNB16 hearing loss.

STRC STRCP1

9.91e-062110234910522
Pubmed

Defective regulation of microRNA target genes in myoblasts from facioscapulohumeral dystrophy patients.

DUX4L9 DUX4

9.91e-062110224145033
Pubmed

Temperature-sensitive Cav1.2 calcium channels support intrinsic firing of pyramidal neurons and provide a target for the treatment of febrile seizures.

CACNA1C CACNA1D

9.91e-062110223761887
Pubmed

PAX8-mediated activation of the wt1 tumor suppressor gene.

WT1 PAX8

9.91e-06211028861958
Pubmed

Non-voltage-gated L-type Ca2+ channels in human T cells: pharmacology and molecular characterization of the major alpha pore-forming and auxiliary beta-subunits.

CACNA1C CACNA1D

9.91e-062110214981074
Pubmed

CaV1.2 and CaV1.3 channel hyperactivation in mouse islet β cells exposed to type 1 diabetic serum.

CACNA1C CACNA1D

9.91e-062110225292336
Pubmed

Ca(v)1.3 channels produce persistent calcium sparklets, but Ca(v)1.2 channels are responsible for sparklets in mouse arterial smooth muscle.

CACNA1C CACNA1D

9.91e-062110217526649
Pubmed

Mechanisms Responsible for ω-Pore Currents in Cav Calcium Channel Voltage-Sensing Domains.

CACNA1D CACNA1S

9.91e-062110228978442
Pubmed

Ligand-activated signal transduction in the 2-cell embryo.

CACNA1C CACNA1D

9.91e-062110212606379
Pubmed

Pyrimidine-2,4,6-triones are a new class of voltage-gated L-type Ca2+ channel activators.

CACNA1C CACNA1D

9.91e-062110224941892
Pubmed

Expression of WT1 and PAX8 in the epithelial tumours of Malaysian women with ovarian cancer.

WT1 PAX8

9.91e-062110228367736
Pubmed

Equal sensitivity of Cav1.2 and Cav1.3 channels to the opposing modulations of PKA and PKG in mouse chromaffin cells.

CACNA1C CACNA1D

9.91e-062110222826131
Pubmed

Transcriptional regulation of L-type calcium channel subtypes Cav1.2 and Cav1.3 by nicotine and their potential role in nicotine sensitization.

CACNA1C CACNA1D

9.91e-062110224470632
Pubmed

Cav1.2 and Cav1.3 L-type calcium channels operate in a similar voltage range but show different coupling to Ca(2+)-dependent conductances in hippocampal neurons.

CACNA1C CACNA1D

9.91e-062110224760982
Pubmed

Deletion of the L-type calcium channel Ca(V) 1.3 but not Ca(V) 1.2 results in a diminished sAHP in mouse CA1 pyramidal neurons.

CACNA1C CACNA1D

9.91e-062110220014384
Pubmed

Role of putative voltage-sensor countercharge D4 in regulating gating properties of CaV1.2 and CaV1.3 calcium channels.

CACNA1C CACNA1D

9.91e-062110230001160
Pubmed

Rescue and worsening of congenital heart block-associated electrocardiographic abnormalities in two transgenic mice.

CACNA1C CACNA1D

9.91e-062110221352396
Pubmed

Molecular nature of anomalous L-type calcium channels in mouse cerebellar granule cells.

CACNA1C CACNA1D

9.91e-062110217409250
Pubmed

Neuronal L-type calcium channels open quickly and are inhibited slowly.

CACNA1C CACNA1D

9.91e-062110216267232
Pubmed

Mutations in a new gene encoding a protein of the hair bundle cause non-syndromic deafness at the DFNB16 locus.

STRC STRCP1

9.91e-062110211687802
Pubmed

Coordinate patterns of estrogen receptor, progesterone receptor, and Wilms tumor 1 expression in the histopathologic distinction of ovarian from endometrial serous adenocarcinomas.

WT1 PGR

9.91e-062110223706170
Pubmed

The role of L-type voltage-gated calcium channels Cav1.2 and Cav1.3 in normal and pathological brain function.

CACNA1C CACNA1D

9.91e-062110224996399
Pubmed

Acyl-CoA thioesterase-2 facilitates mitochondrial fatty acid oxidation in the liver.

ACOT1 ACOT2

9.91e-062110225114170
Pubmed

Expression and function of system N glutamine transporters (SN1/SN2 or SNAT3/SNAT5) in retinal ganglion cells.

SLC38A5 SLC38A3

9.91e-062110218689705
Pubmed

Genetic, cellular, and functional evidence for Ca2+ inflow through Cav1.2 and Cav1.3 channels in murine spiral ganglion neurons.

CACNA1C CACNA1D

9.91e-062110224849370
Pubmed

Endogenous cardiac Ca2+ channels do not overcome the E-C coupling defect in immortalized dysgenic muscle cells: evidence for a missing link.

CACNA1C CACNA1S

9.91e-06211027635187
Pubmed

Divide and conquer: an L-type voltage-gated calcium channel subtype finds a role in conditioned fear.

CACNA1C CACNA1D

9.91e-062110217015854
Pubmed

[The expression of genes encoding the voltage-dependent L-type Ca2+ channels in proliferating and differentiating C2C12 myoblasts of mice].

CACNA1D CACNA1S

9.91e-062110221789999
Pubmed

Müllerian and eccrine cutaneous ciliated cysts: two different entities? The contribution of WT-1 and PAX8 to diagnosis.

WT1 PAX8

9.91e-062110223550799
Pubmed

Cav1.2 and Cav1.3 L-type calcium channels regulate dopaminergic firing activity in the mouse ventral tegmental area.

CACNA1C CACNA1D

9.91e-062110224848473
Pubmed

Value of PAX8 and WT1 Immunostaining in Confirming the Ovarian Origin of Metastatic Carcinoma in Serous Effusion Specimens.

WT1 PAX8

9.91e-062110222261458
Pubmed

C-terminal ADAMTS-18 fragment induces oxidative platelet fragmentation, dissolves platelet aggregates, and protects against carotid artery occlusion and cerebral stroke.

ITGB3 ADAMTS18

9.91e-062110219218546
Pubmed

Characterization of an MPS I-H knock-in mouse that carries a nonsense mutation analogous to the human IDUA-W402X mutation.

IDUA GUSB

9.91e-062110219751987
Pubmed

Epistatic interaction of genetic depression risk variants in the human subgenual cingulate cortex during memory encoding.

CACNA1C PCLO

9.91e-062110224643163
Pubmed

Voltage-activated calcium channel expression profiles in mouse brain and cultured hippocampal neurons.

CACNA1C CACNA1D CACNA1S

1.36e-0515110320188150
Pubmed

Mutations in MINAR2 encoding membrane integral NOTCH2-associated receptor 2 cause deafness in humans and mice.

DUX4L9 DUX4L2 DUX4L4

1.36e-0515110335727972
Pubmed

Differential neuronal targeting of a new and two known calcium channel β4 subunit splice variants correlates with their regulation of gene expression.

CACNA1C CACNA1D CACNA1S

1.36e-0515110324453333
Pubmed

Proteomic analysis identifies transcriptional cofactors and homeobox transcription factors as TBX18 binding proteins.

DUX4L9 DUX4L2 DUX4L4

1.36e-0515110330071041
Pubmed

Sorcin associates with the pore-forming subunit of voltage-dependent L-type Ca2+ channels.

CACNA1C CACNA1S

2.97e-05311029668070
Pubmed

PAX8-positive Biphasic Synovial Sarcoma Expressing Hormonal Receptors.

PGR PAX8

2.97e-053110228248726
Pubmed

Direct progesterone receptor and indirect androgen receptor interactions with the kallikrein-related peptidase 4 gene promoter in breast and prostate cancer.

KLK14 PGR

2.97e-053110219147544
Pubmed

Cochlear outer hair cell horizontal top connectors mediate mature stereocilia bundle mechanics.

STRC STRCP1

2.97e-053110230801007
Pubmed

Expression, regulation, and function of paired-box gene 8 in the human placenta and placental cancer cell lines.

WT1 PAX8

2.97e-053110215961562
Pubmed

Triad proteins and intracellular Ca2+ transients during development of human skeletal muscle cells in aneural and innervated cultures.

CACNA1C CACNA1S

2.97e-053110211206130
Pubmed

mRNA for cardiac calcium channel is expressed during development of skeletal muscle.

CACNA1C CACNA1S

2.97e-05311028381753
Pubmed

Acyl-Coa Thioesterases: A Rheostat That Controls Activated Fatty Acids Modulates Dengue Virus Serotype 2 Replication.

ACOT1 ACOT2

2.97e-053110235215835
Pubmed

G protein-gated IKACh channels as therapeutic targets for treatment of sick sinus syndrome and heart block.

CACNA1C CACNA1D

2.97e-053110226831068
Pubmed

Progesterone acts via the progesterone receptor to induce adamts proteases in ovarian cancer cells.

ADAMTS4 PGR

2.97e-053110226916548
Pubmed

Comparative in situ hybridization analysis of PAX2, PAX8, and WT1 gene transcription in human fetal kidney and Wilms' tumors.

WT1 PAX8

2.97e-05311027856737
Pubmed

Truncation of murine CaV1.2 at Asp 1904 increases CaV1.3 expression in embryonic atrial cardiomyocytes.

CACNA1C CACNA1D

2.97e-053110223338940
Pubmed

AKAP5 complex facilitates purinergic modulation of vascular L-type Ca2+ channel CaV1.2.

CACNA1C ADCY5

2.97e-053110233082339
Pubmed

The intracellular II-III loops of Cav1.2 and Cav1.3 uncouple L-type voltage-gated Ca2+ channels from glucagon-like peptide-1 potentiation of insulin secretion in INS-1 cells via displacement from lipid rafts.

CACNA1C CACNA1D

2.97e-053110219351867
Pubmed

Truncation of murine CaV1.2 at Asp-1904 results in heart failure after birth.

CACNA1C CACNA1D

2.97e-053110221832054
Pubmed

Potent inhibition of L-type Ca2+ currents by a Rad variant associated with congestive heart failure.

CACNA1C CACNA1D

2.97e-053110223973784
Pubmed

Peroxisome proliferator-induced long chain acyl-CoA thioesterases comprise a highly conserved novel multi-gene family involved in lipid metabolism.

ACOT1 ACOT2

2.97e-053110210567408
Pubmed

MicroRNA-1976 regulates degeneration of the sinoatrial node by targeting Cav1.2 and Cav1.3 ion channels.

CACNA1C CACNA1D

2.97e-053110231302118
Pubmed

Distinct localization and modulation of Cav1.2 and Cav1.3 L-type Ca2+ channels in mouse sinoatrial node.

CACNA1C CACNA1D

2.97e-053110223045342
Pubmed

Up-Regulated MicroRNA-27b Promotes Adipocyte Differentiation via Induction of Acyl-CoA Thioesterase 2 Expression.

ACOT1 ACOT2

2.97e-053110231930115
Pubmed

Ligand-associated ERBB2/3 activation confers acquired resistance to FGFR inhibition in FGFR3-dependent cancer cells.

ERBB3 FGFR3

2.97e-053110224909170
Pubmed

Cav1.3 channels control D2-autoreceptor responses via NCS-1 in substantia nigra dopamine neurons.

CACNA1C CACNA1D

2.97e-053110224934288
Pubmed

Recruitment of vimentin to the cell surface by beta3 integrin and plectin mediates adhesion strength.

ITGB3 PLEC

2.97e-053110219366731
Pubmed

Nephrons require Rho-kinase for proximal-distal polarity development.

WT1 PAX8

2.97e-053110224045698
Pubmed

The gene organization of the human beta 7 subunit, the common beta subunit of the leukocyte integrins HML-1 and LPAM-1.

ITGB3 ITGB7

2.97e-05311021382574
Pubmed

Stereocilin-deficient mice reveal the origin of cochlear waveform distortions.

STRC STRCP1

5.92e-054110218849963
Pubmed

Deducing the stage of origin of Wilms' tumours from a developmental series of Wt1-mutant mice.

WT1 PAX8

5.92e-054110226035382
Pubmed

Molecular cloning and characterization of two mouse peroxisome proliferator-activated receptor alpha (PPARalpha)-regulated peroxisomal acyl-CoA thioesterases.

ACOT1 ACOT2

5.92e-054110215007068
Pubmed

Cancer stem cell differentiation: TGFβ1 and versican may trigger molecules for the organization of tumor spheroids.

COL7A1 ITGB3

5.92e-054110224927163
Pubmed

SSeCKS sequesters cyclin D1 in glomerular parietal epithelial cells and influences proliferative injury in the glomerulus.

WT1 PAX8

5.92e-054110222249313
Pubmed

Interaction of ATP sensor, cAMP sensor, Ca2+ sensor, and voltage-dependent Ca2+ channel in insulin granule exocytosis.

CACNA1S ABCC8

5.92e-054110214660679
Pubmed

DUX4c is up-regulated in FSHD. It induces the MYF5 protein and human myoblast proliferation.

DUX4L9 DUX4

5.92e-054110219829708
Pubmed

Molecular coupling of a Ca2+-activated K+ channel to L-type Ca2+ channels via alpha-actinin2.

CACNA1C CACNA1D

5.92e-054110217110593
Pubmed

Stromal Pbrm1 mediates chromatin remodeling necessary for embryo implantation in the mouse uterus.

PGR PAX8

5.92e-054110238426493
Cytoband4q35.2

DUX4L2 DUX4L5 DUX4L6 DUX4L3 DUX4L4 DUX4L7

4.68e-112711064q35.2
CytobandEnsembl 112 genes in cytogenetic band chr4q35

DUX4L9 DUX4L2 DUX4 DUX4L5 DUX4L6 DUX4L3 DUX4L4 DUX4L7

4.61e-101171108chr4q35
Cytoband14q24.3

ACOT1 ACOT6 PROX2 DLST ACOT2

3.17e-0693110514q24.3
CytobandEnsembl 112 genes in cytogenetic band chr14q24

ACOT1 ACOT6 PROX2 DLST ACOT2

1.26e-042001105chr14q24
Cytoband9q34.11

PHYHD1 HMCN2 SWI5

2.87e-045311039q34.11
Cytoband3q21.1

PARP14 ADCY5

1.05e-032011023q21.1
Cytoband15q15.3

STRC STRCP1

1.65e-0325110215q15.3
Cytoband3q25.1

IGSF10 MED12L

2.86e-033311023q25.1
GeneFamilyPRD class homeoboxes and pseudogenes

DUX4L9 DUX4L2 PAX8 DUX4L5 DUX4L6 DUX4L3 DUX4L4 DUX4L7

7.08e-0992808521
GeneFamilyAcyl-CoA thioesterases

ACOT1 ACOT6 ACOT2

9.79e-061080341
GeneFamilyCalcium voltage-gated channel subunits

CACNA1C CACNA1D CACNA1S

2.02e-0426803253
GeneFamilyCD molecules|Integrin beta subunits

ITGB3 ITGB7

6.82e-0498021159
GeneFamilyFibronectin type III domain containing

COL7A1 VWA1 DSCAML1 PTPRJ ROBO3

7.18e-04160805555
GeneFamilyBlood group antigens|CD molecules|I-set domain containing|Immunoglobulin like domain containing

DSCAML1 IGSF10 HMCN2 FGFR3 ROBO3

7.39e-04161805593
GeneFamilyADAM metallopeptidases with thrombospondin type 1 motif

ADAMTS4 ADAMTS18

3.15e-031980250
GeneFamilyProtein tyrosine phosphatases, receptor type

PTPRJ PTPRN

3.84e-0321802813
GeneFamilyRNA polymerase subunits

POLR3F POLR1D

7.26e-0329802726
GeneFamilyImmunoglobulin like domain containing

DSCAML1 HMCN2 FCRL5 ROBO3

1.06e-02193804594
ToppCellPrimary_Visual_cortex_(V1C)-Non-neuronal-Macroglial-Astro-Astrocyte-Astro_L1-6_FGFR3_ETNPPL|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

CACNA1S PHYHD1 ADGRV1 FREM2 RAB34 GAREM2 FGFR3 SLC38A3

1.35e-08186104873cf266aeecd3cc15e8cb6094588a393bca8fbe6
ToppCelldroplet-Trachea-3m-Mesenchymal-fibroblast-fibroblast_of_trachea-|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CACNA1D ADAMTS4 INTS1 PHYHD1 PARP14 PROX2 ADAMTS18

1.34e-071671047774f3264318b002d0df5d06d41d645366038d0bf
ToppCelldroplet-Pancreas|droplet / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ZCCHC18 CACNA1D PCLO PTPRN FAM151A ABCC8 BACE2

2.89e-0718710475f4df092452d8672bda4059c794e099ba3f5a8fa
ToppCellPrimary_Visual_cortex_(V1C)-Non-neuronal-Macroglial-Astro|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

CACNA1S PHYHD1 ADGRV1 RAB34 GAREM2 FGFR3 SLC38A3

3.22e-07190104778cc6c28b31de041c24175a98f47da256ecc15a2
ToppCellPrimary_Visual_cortex_(V1C)-Non-neuronal-Macroglial-Astro-Astrocyte|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

CACNA1S PHYHD1 ADGRV1 RAB34 GAREM2 FGFR3 SLC38A3

3.22e-071901047e67d9400467b438592690b23d681e6c2fb8f09fd
ToppCellPBMC-Mild-Myeloid-cDC-cDC-cDC_4|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

PHYHD1 IGSF10 MED12L ADGRF3 BCAR3 ROBO3

1.62e-06153104691e9d70a5d3f6fd68c284ed0cc113f03d7d1e10b
ToppCellPBMC-Mild-Myeloid-cDC-cDC-cDC_4|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

PHYHD1 IGSF10 MED12L ADGRF3 BCAR3 ROBO3

1.62e-061531046f17f62646633cf95c810dcd5328978058741b276
ToppCellfacs-Lung-EPCAM-24m-Myeloid-Plasmacytoid_Dendritic|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HIVEP1 MOGAT1 ITGB3 ADCY5 PAFAH1B3 HAAO

2.68e-061671046e0f2509e86302eca8352821bce12597f6c51fc24
ToppCellfacs-Lung-EPCAM-24m-Myeloid-plasmacytoid_dendritic_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HIVEP1 MOGAT1 ITGB3 ADCY5 PAFAH1B3 HAAO

2.68e-061671046b25646b6653cd8814dbeae4c74ce899ede105200
ToppCellPBMC-Convalescent-Lymphocyte-B-B_cell-B_naive-B_naive-5|Convalescent / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

ZNF577 MEX3A SHPK FCRL5 BACE2 IL4R

3.08e-06171104623b3120706bb9c20b9214fe3760c6d7a84f1e749
ToppCellfacs-Pancreas-Exocrine-3m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CACNA1C CACNA1D KDM4C PCLO FAM151A BACE2

3.40e-061741046f1fe1f4216748a9562dd03bd48c70b23c7ff4d1d
ToppCellfacs-GAT-Fat-24m-Lymphocytic-B_cell|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ZCCHC18 CACNA1S ITGB7 PAFAH1B3 FCRL5 BCAR3

3.75e-061771046f4afe10522eed77318954210224496f09d372532
ToppCellfacs-Trachea-24m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell-smooth_muscle_cell_of_trachea_l6-17|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CACNA1C DSCAML1 SLCO5A1 ABCC8 MED12L POLQ

3.75e-0617710468abdf1d970b2f15e17e185f3e612dd5065c88757
ToppCellSomatosensory_Cortex_(S1)-Non-neuronal-Macroglial-Astro-Astrocyte-Astro_L1_FGFR3_MT1G|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

PHYHD1 ADGRV1 RAB34 FAM151A ADAMTS18 FGFR3

4.27e-0618110460c3f469bed108994ed696230e3c30343f7a301d3
ToppCellfacs-Pancreas-Endocrine-24m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CACNA1D PCLO PTPRN FAM151A ABCC8 BACE2

5.31e-061881046a91443aa8fa8fa87f7501c59219daa0305bd0bbf
ToppCellRA-14._Fibroblast_III|World / Chamber and Cluster_Paper

ADAMTS4 WT1 SLC2A13 BACE2 LONRF2 ALG13

5.47e-061891046b6e12d24d2b0735730bdc625f8318c1c9c2a9b3b
ToppCellprimary_auditory_cortex_(A1C)-Non-neuronal-Macroglial-Astro-Astrocyte-Astro_L1-6_FGFR3_ETNPPL|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

PHYHD1 ADGRV1 FREM2 RAB34 GAREM2 FGFR3

5.64e-0619010465c64b727669b23d2a23c8ad1d5d6caab7af37d56
ToppCellSomatosensory_Cortex_(S1)-Non-neuronal-Macroglial-Astro-Astrocyte-Astro_L1-6_FGFR3_ETNPPL|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

PHYHD1 ADGRV1 RAB34 GAREM2 FGFR3 SLC38A3

5.64e-061901046b56c55f608b30f7379941ac7d5f0f5200f305fca
ToppCellfacs-Pancreas|facs / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ZCCHC18 CACNA1D PCLO PTPRN FAM151A ABCC8

5.81e-061911046d48e5f67d384226add7d7fb2a124954136e09a82
ToppCell5'-Adult-LymphNode-Mesenchymal|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ADAMTS4 WT1 IGSF10 CCDC181 LONRF2 SOD3

5.81e-061911046054e9a79bd1486fd812bc7418fb091664fe3a646
ToppCellPrimary_Motor_Cortex_(M1)-Non-neuronal-Macroglial-Astro-Astrocyte-Astro_L1-6_FGFR3_ETNPPL|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

PHYHD1 ADGRV1 RAB34 GAREM2 FGFR3 SLC38A3

5.99e-06192104643beaac1de99b9c1a6dab4a450b4e81286987b64
ToppCell5'-Adult-LymphNode-Mesenchymal-fibroblastic|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ADAMTS4 WT1 IGSF10 CCDC181 LONRF2 SOD3

5.99e-061921046d7faa993f68e530ad55185505384ae155d36c222
ToppCellLA-14._Fibroblast_III|LA / Chamber and Cluster_Paper

ADAMTS4 WT1 LPCAT2 SLC2A13 CCDC181 LONRF2

6.17e-0619310467426c291bac59e539c427bcaae18abc7d397d44e
ToppCellC_06|World / shred on cell type and cluster

COL11A2 RPS2 VWA1 ERN2 BACE2 SOD3

6.35e-0619410465cb42e09f380c4468cdc603ec0c3de35eadd3213
ToppCellLA-14._Fibroblast_III|World / Chamber and Cluster_Paper

ADAMTS4 WT1 LPCAT2 SLC2A13 CCDC181 LONRF2

6.35e-061941046803fa83ceada17c38ca9f933b888f7e7b0b90761
ToppCellPCW_07-8.5-Epithelial-Epithelial_neuroendo|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

PCLO ADGRV1 FREM2 PTPRN ABCC8 LONRF2

6.35e-061941046b30379f8dc41c86c746af9930541fbb4819d8fa0
ToppCelldistal-Epithelial-Differentiating_Basal-3|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

COL7A1 ERBB3 PHYHD1 ERN2 NKX2-8 FGFR3

6.54e-0619510463fe6e49a9161fc9e5160251e6932cb5378175a54
ToppCellfacs-Pancreas-Endocrine-18m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PCLO PTPRN FAM151A ABCC8 SLC2A13 BACE2

6.54e-061951046bd8e24dd598990204998d1dd853ba7a53dc0107e
ToppCelldroplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CACNA1D PCLO PTPRN FAM151A ABCC8 BACE2

6.54e-0619510463e519cffa6144a62b06124642a14c9ff39b76554
ToppCelldroplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CACNA1D PCLO PTPRN FAM151A ABCC8 BACE2

6.54e-0619510467796ea9247f4c63762f0de8490fed08b9717fa23
ToppCelldistal-3-Epithelial-Differentiating_Basal|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

COL7A1 ERBB3 PHYHD1 ERN2 NKX2-8 FGFR3

6.74e-06196104677635a0f86910c4019d3370e9c8ba41de176bcf3
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CACNA1D DSCAML1 ADCY5 SLC45A4 PTPRJ PAX8

6.94e-0619710467e93a97b5ac5ae2f77a4b3141082a1463fed00dd
ToppCellMacroglial-Astrocytes-GFAP---|Macroglial / cells hierarchy compared to all cells using T-Statistic

PHYHD1 ADGRV1 RAB34 ADAMTS18 FGFR3 PLEC

7.56e-06200104688d66550781a3c9102ff7455f5cff6fb072943cd
ToppCellMacroglial-Astrocytes-GFAP-|Macroglial / cells hierarchy compared to all cells using T-Statistic

PHYHD1 ADGRV1 RAB34 ADAMTS18 FGFR3 PLEC

7.56e-062001046d6a059b0ef763c281c60b1ac76da6079ea822f80
ToppCellMacroglial-Astrocytes-GFAP--|Macroglial / cells hierarchy compared to all cells using T-Statistic

PHYHD1 ADGRV1 RAB34 ADAMTS18 FGFR3 PLEC

7.56e-06200104616269fa4adb28fc6ed032bbdba8781237dd0d249
ToppCellMacroglial-Astrocytes-GFAP----L1-2|Macroglial / cells hierarchy compared to all cells using T-Statistic

PHYHD1 ADGRV1 RAB34 ADAMTS18 FGFR3 PLEC

7.56e-062001046c6f43bbbd5df5f2c19ae385f1a6b6a330abede2f
ToppCellMacroglial-Astrocytes-GFAP|Macroglial / cells hierarchy compared to all cells using T-Statistic

PHYHD1 ADGRV1 RAB34 ADAMTS18 FGFR3 PLEC

7.56e-06200104679634b1086934412ae92f259ab43554ce545008f
ToppCellTracheal-NucSeq-Epithelial-Epi_submucosal-gland|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

ERBB3 ADGRV1 RRBP1 ERN2 PTPRJ BACE2

7.56e-0620010460eb9ad8c0373bcc62029ec21c590ed03aaacd039
ToppCellLPS-antiTNF-Unknown-Endothelial-Pericyte_2|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

MOGAT1 ADCY5 ADAMTS18 POLQ IQGAP3

1.47e-05132104502491930097b75aaeedab9e8200711b0dc610944
ToppCelldroplet-Pancreas-Exocrine-21m-Epithelial-nan|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RPS2 SLC38A5 PGR FREM2 SLC38A3

1.52e-05133104591e4556658e49f92946d48b194df64c5fc5758fe
ToppCell3'-Airway_Nasal-Epithelial-Airway_epithelium-respiratory_basal_cell-Basal_resting-Basal_resting_L.0.0.0.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SLC38A5 ADCY5 MED12L FGFR3 SLC38A3

2.99e-05153104582b77c8bae49dd63b8f10eb67df66ca71d0bb315
ToppCellfacs-Heart-RA-24m-Lymphocytic-B_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CACNA1S ITGB7 PAFAH1B3 HAAO FCRL5

4.28e-05165104536415924d05373e9dd3665be599f4f3f40bf0497
ToppCellfacs-Heart-RA-24m-Lymphocytic-B_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CACNA1S ITGB7 PAFAH1B3 HAAO FCRL5

4.28e-05165104556310fddd3d8e4afdfde066d26cee9747e5b8c6a
ToppCell368C-Myeloid-Macrophage-FABP4+_Macrophage_2|Macrophage / Donor, Lineage, Cell class and subclass (all cells)

ZCCHC18 ADGRV1 ADCY5 HMCN2 SHPK

4.28e-0516510453d2acdae0dd2b79a15f74158e8e566ce22b4218e
ToppCellTCGA-Ovary-Primary_Tumor-Ovarian_Carcinoma-Serous_Cystadenocarcinoma-1|TCGA-Ovary / Sample_Type by Project: Shred V9

ZCCHC18 ADGRV1 FREM2 GAREM2 CCDC181

4.28e-0516510452ca1154a8692af311d99a4d3aa2f2ac3d23a4310
ToppCellAdult-Mesenchymal-vascular_smooth_muscle_cell-D175|Adult / Lineage, Cell type, age group and donor

CACNA1C ADCY5 ITGB7 HMCN2 ROBO3

4.54e-051671045c4e321bb87512ea839f324c92c0f1afea891483f
ToppCell368C-Myeloid-Macrophage-FABP4+_Macrophage_2|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

ZCCHC18 ADGRV1 ADCY5 HMCN2 SHPK

5.08e-051711045e59afa0a773dca3b9c208d17510ea55703b42598
ToppCellInfluenza_Severe-B_intermediate|World / Disease group and Cell class

ERBB3 MED12L FCRL5 BCAR3 BACE2

5.08e-0517110454d33e1dc1efc423dbdd5f4cca6d6440a68add8d0
ToppCellwk_20-22-Epithelial-Proximal_epithelial-intermediate_neuroendocrine|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

PCLO DSCAML1 SLCO5A1 PTPRN ABCC8

5.08e-051711045b7cddb8f726a43fb8a37f3e67a3f722e2178fd7a
ToppCelldroplet-Limb_Muscle-nan-21m-Lymphocytic-B_cell|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ZCCHC18 CACNA1S ITGB7 PAFAH1B3 FCRL5

5.22e-05172104562734d231290ca725276dc62faa2ac87bd1b37b8
ToppCellHealthy_donor-HSPC|Healthy_donor / disease group, cell group and cell class (v2)

CACNA1C IGSF10 MEX3A MED12L POLQ

5.22e-051721045bc7549faadfc92c683c0e26bea380458706774b5
ToppCell390C-Lymphocytic-ILC-ILC-2|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

ERBB3 ZNF577 CDAN1 BACE2 SOD3

5.22e-05172104584d16cd7f618c94888920680bdc9e7130d73fd75
ToppCellInfluenza_Severe-B_intermediate|Influenza_Severe / Disease group and Cell class

ERBB3 MED12L FCRL5 BCAR3 BACE2

5.51e-0517410454276bdaac53aebd3084323a90ecde572d3177446
ToppCellSubstantia_nigra-Macroglia|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

ERBB3 COL11A2 ADAMTS4 ACOT1 GAREM2

5.51e-0517410457e7f7ca9a413ec255e54621800a279c771b9e6b7
ToppCellfacs-Heart-LA-24m-Lymphocytic-B_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ITGB7 PTPRJ PAFAH1B3 FCRL5 BCAR3

5.82e-051761045077f3fe5e3482ea3f639d789bd3d584161b36c02
ToppCellCOVID-19-kidney-CD-IC-A|COVID-19 / Disease (COVID-19 only), tissue and cell type

CACNA1D DSCAML1 PAX8 ADAMTS18 LONRF2

5.82e-05176104545028197364c64e93e3ffe86aff773d47a477d49
ToppCellfacs-Heart-LA-24m-Lymphocytic-B_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ITGB7 PTPRJ PAFAH1B3 FCRL5 BCAR3

5.82e-051761045fc2ba468677b19b55130c1f06737f40300cd9d2e
ToppCellP15-Epithelial-epithelial_progenitor_cell-epithelial_unknown_3|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

ADAMTS4 VWA1 ITGB3 LIMK1 SHPK

5.82e-051761045792f414f5092aba14260b8e16378e793a822498e
ToppCellfacs-Lung-3m-Hematologic-myeloid-myeloid_dendritic_cell-dendritic_cell|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

TMCO6 ITGB7 USP40 HAAO CCDC181

6.14e-05178104589f0537459a321ded956bf70ad56fefc0854f8b0
ToppCellfacs-Pancreas-Exocrine-3m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CACNA1C CACNA1D PCLO FAM151A BACE2

6.14e-051781045fcbbcc44271515de1969b4732b6441c012693d5f
ToppCellwk_20-22-Epithelial-Proximal_epithelial-GHRL+_neuroendocrine|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

PCLO DSCAML1 PTPRN ABCC8 LONRF2

6.30e-05179104506f92c884189197c86793191c05f65e34925c097
ToppCellCOPD-Stromal-SMC|World / Disease state, Lineage and Cell class

CACNA1C ADAMTS4 ADCY5 PGR SOD3

6.30e-051791045b2709537ec1b46457ab85261f4cdd354e60a8b29
ToppCellControl-Epithelial-Goblet|Control / Disease state, Lineage and Cell class

ERBB3 KLK14 ERN2 FGFR3 BACE2

6.47e-0518010455293d23b8b8ea587239ffde561b70bad01632521
ToppCellfacs-SCAT-Fat-24m-Lymphocytic-B_cell|SCAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CACNA1S ITGB7 PAFAH1B3 FCRL5 BCAR3

6.64e-05181104514faef1dde781d501834379f2a6413e8d6a80b72
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_3|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ADGRV1 DSCAML1 ADCY5 PAX8 SLC2A13

6.82e-051821045eb138aa1dca9373f1586600f258df06dcf56d81f
ToppCellInt-URO-Lymphocyte-B-B_naive|Int-URO / Disease, Lineage and Cell Type

RPS2 STK17A FCRL5 BACE2 IL4R

6.82e-051821045af7482c63e87a53cf686200a8f4d5b9749235dcd
ToppCellfacs-Lung-3m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l25-31|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ERBB3 COL11A2 VWA1 SHPK PROX2

6.82e-051821045a1c0e4090a9e7aa4941a40c817d178de144888b6
ToppCell3'-Adult-LargeIntestine-Epithelial-Tuft-related-Microfold_cell|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

COL11A2 PAX8 HAAO PLEC SOD3

6.82e-051821045b4f347fb684f6840c166d7473f3f56389f69c14b
ToppCellfacs-Mammary_Gland-Mammary_Gland-3m-Epithelial-luminal_epithelial_cell_of_mammary_gland|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ERBB3 ACOT1 PGR ABCC8 ACOT2

7.00e-0518310457eaa6ef7c6cf848fd6489f97677f4406318da22f
ToppCelldroplet-Heart-HEART_(ALL_MINUS_AORTA)-30m-Neuronal-nan|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ACOT1 ITGB3 PTPRJ SHPK CCDC181

7.18e-051841045e33bb572af9dfd11127105f1ac99bc958a7cafbb
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-24m-Epithelial-Bergmann_glial_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PHYHD1 RAB34 GAREM2 ADAMTS18 FGFR3

7.18e-051841045f6148e9591e8845cc62668e49fd52755257cdc7e
ToppCellBac-SEP-Lymphocyte-B-B_naive|Bac-SEP / Disease, Lineage and Cell Type

RPS2 STK17A FCRL5 BACE2 IL4R

7.37e-0518510454d9e1eeb353c0b1f82f557856e99c8bf04aa2a7f
ToppCellControl-Epithelial-Goblet|World / Disease state, Lineage and Cell class

ERBB3 KLK14 ERN2 FGFR3 BACE2

7.37e-0518510459a793e6016295a63820e9d7563f195494ac692e7
ToppCellMid-temporal_gyrus_(MTG)-Non-neuronal-Macroglial-Astro-Astrocyte-Astro_L1_FGFR3_MT1G|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

PHYHD1 ADGRV1 RAB34 ADAMTS18 FGFR3

7.56e-05186104541e03be964044dae690d566bd078dab3d8045eba
ToppCell10x5'v1-week_14-16-Mesenchymal_osteo-stroma-chondrocyte|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

ERBB3 COL11A2 FGFR3 SLC38A3 SOD3

7.56e-05186104580a0a42ca8585cdb1dda57a18c254316a126ee64
ToppCelldroplet-Liver-LIVER_HEP-30m-Lymphocytic-nan|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ZCCHC18 PCLO CDAN1 ABCC8 CCDC181

7.56e-051861045f5468e03321ea2083e223eb0d92c3a9307039569
ToppCellprimary_auditory_cortex_(A1C)-Non-neuronal-Macroglial-Astro-Astrocyte-Astro_L1_FGFR3_MT1G|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

PHYHD1 ADGRV1 GAREM2 ADAMTS18 FGFR3

7.75e-051871045401be371b32066db926de3415bb4ce9465749dc3
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ADGRV1 DSCAML1 ADCY5 PAX8 SLC2A13

7.95e-051881045af740fa78542438fdff627ea1f74f4eee43316be
ToppCellPCW_13-14-Epithelial-Epithelial_airway-epi_proximal_progenitor1_(6)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

ERBB3 PCLO ADGRV1 FREM2 LONRF2

7.95e-0518810450d86044bc340e3efb90d0022dd299873639d831c
ToppCellCOVID-19-kidney-DCT|COVID-19 / Disease (COVID-19 only), tissue and cell type

CACNA1D DSCAML1 FREM2 PAX8 BACE2

7.95e-0518810451d56cd409793f05cca20757ab26e91f1a1ee67b5
ToppCellfacs-Pancreas-Endocrine-24m-Epithelial-nan|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ZCCHC18 PTPRN FAM151A ABCC8 BACE2

7.95e-05188104563773854bf8430fb8229edb385b953a89833d08c
ToppCellLV-14._Fibroblast_III|World / Chamber and Cluster_Paper

ADAMTS4 WT1 SLC2A13 LONRF2 ALG13

8.15e-0518910453922135d1f6fc768d71ba3b465585fead6ea68a8
ToppCellRA-14._Fibroblast_III|RA / Chamber and Cluster_Paper

ADAMTS4 WT1 SLC2A13 LONRF2 ALG13

8.15e-05189104546e9a58aacd79db5a02898a8c7244e1884adcfd1
ToppCellControl-Stromal_mesenchymal-Lung_smooth_muscle|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CACNA1C CACNA1D ADCY5 LONRF2 SOD3

8.15e-05189104545e588b2a4ad9e3ff74e22d9d627ed3571f3b8b8
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_ascending_limb_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ADGRV1 DSCAML1 PAX8 SLC2A13 SOD3

8.35e-0519010451cf023e3c6924d6a06f353d4b62444b6f2fee8a7
ToppCellSomatosensory_Cortex_(S1)-Non-neuronal-Macroglial-Astro|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

PHYHD1 ADGRV1 RAB34 FGFR3 SLC38A3

8.35e-0519010453a55cc5dc2549788bfe55f649686887b21a1fdd2
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

FREM2 LPCAT2 PAX8 FGFR3 SOD3

8.35e-051901045b855b8b7d3439023390ca44629c1a99f5d4c6801
ToppCellwk_08-11-Epithelial-Proximal_epithelial-intermediate_neuroendocrine|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

PCLO KLK14 PTPRN ABCC8 LONRF2

8.35e-0519010455f1863bce9400b7c932f0e4d0e012ec4e8d7e555
ToppCellSomatosensory_Cortex_(S1)-Non-neuronal-Macroglial-Astro-Astrocyte|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

PHYHD1 ADGRV1 RAB34 FGFR3 SLC38A3

8.35e-0519010451c3d601422efa60fad8565f9ccd9032b847e4a91
ToppCelldroplet-Pancreas-Endocrine-18m-Epithelial|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PCLO PTPRN FAM151A ABCC8 BACE2

8.56e-051911045fd01a206763dfb6d52cca67123571936b4a8e1a0
ToppCellControl-Stromal_mesenchymal|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CACNA1C CACNA1D ADCY5 IGSF10 SOD3

8.56e-05191104514057205ddb9b4bbc582d1358d13cf36d979a61b
ToppCellfacs-Pancreas-Endocrine-24m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PCLO PTPRN FAM151A ABCC8 BACE2

8.56e-0519110453387b95a3f2445c672d407922fdce3a91eabaef8
ToppCellfacs-Pancreas-Endocrine-24m-Epithelial|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ZCCHC18 PTPRN FAM151A ABCC8 BACE2

8.56e-051911045a251b134f67a0a1ef3a42f50042f128a17f20b22
ToppCellControl-Stromal_mesenchymal-Lung_smooth_muscle-Myofibroblast|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CACNA1C CACNA1D ADCY5 LONRF2 SOD3

8.56e-051911045b133ee1c0e58d00ddd2e4e05b01fd04947524c18
ToppCellprimary_auditory_cortex_(A1C)-Non-neuronal-Macroglial-Astro-Astrocyte|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

PHYHD1 ADGRV1 RAB34 GAREM2 FGFR3

8.77e-051921045f7e4509003d71f805b9d4587098e90d2897b6739
ToppCelldroplet-Pancreas-Endocrine-18m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PCLO PTPRN FAM151A ABCC8 BACE2

8.77e-0519210451304e69c92cef3bd8c82e3c035a7562f5440139a
ToppCellnucseq-Endothelial-Endothelial_Vascular-Endothelial_large_blood_vessel-SVEC|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

ADAMTS4 VWA1 ITGB3 BACE2 SLC38A3

8.77e-051921045c3dda7c48732b0b8bde36de282d64192f5e9b98f
ToppCelldroplet-Pancreas-Endocrine-18m|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PCLO PTPRN FAM151A ABCC8 BACE2

8.77e-0519210454510aa262da8dcf7c944b3907a51aba5a9397a4e
ToppCellprimary_auditory_cortex_(A1C)-Non-neuronal-Macroglial-Astro|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

PHYHD1 ADGRV1 RAB34 GAREM2 FGFR3

8.77e-051921045705ce805cb00a53793b57bcf466d0fbec590a83c
ToppCellPrimary_Motor_Cortex_(M1)-Non-neuronal-Macroglial-Astro-Astrocyte|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

PHYHD1 ADGRV1 RAB34 GAREM2 FGFR3

8.99e-051931045b03d908d4b8940927f72c76a1b0f237d13f39056
DrugNisoldipine

CACNA1C CACNA1D CACNA1S

1.06e-0651093DB00401
DrugNilvadipine

CACNA1C CACNA1D CACNA1S

1.06e-0651093DB06712
DrugCPU-23

CACNA1C CACNA1D CACNA1S

2.11e-0661093CID003036051
DrugAmlodipine

CACNA1C CACNA1D CACNA1S

3.68e-0671093DB00381
DrugIsradipine

CACNA1C CACNA1D CACNA1S

3.68e-0671093DB00270
DrugNifedipine

CACNA1C CACNA1D CACNA1S

5.87e-0681093DB01115
DrugNitrendipine

CACNA1C CACNA1D CACNA1S

5.87e-0681093DB01054
DrugCinnarizine

CACNA1C CACNA1D CACNA1S

8.78e-0691093DB00568
DrugNimodipine

CACNA1C CACNA1D CACNA1S

8.78e-0691093DB00393
DrugMibefradil

CACNA1C CACNA1D CACNA1S

1.71e-05111093DB01388
DrugFelodipine

CACNA1C CACNA1D CACNA1S

1.71e-05111093DB01023
Drug17 alpha-hydroxypregnanolone

CYP21A2 GUSB

2.27e-0521092CID000101773
DrugAC1L9ADJ

CYP21A2 GUSB

2.27e-0521092CID000441003
DrugAC1L1JG6

CACNA1C CACNA1D CACNA1S

3.74e-05141093CID000005026
DrugFPL 64176

CACNA1C CACNA1D CACNA1S

4.66e-05151093CID000003423
DrugMetoclopramide monohydrochloride [7232-21-5]; Down 200; 11.8uM; MCF7; HT_HG-U133A

PCLO TMCO6 IDUA ERN2 PGR LIMK1 DOCK6

4.77e-0519810974750_DN
DrugVerapamil

CACNA1C CACNA1D CACNA1S

5.71e-05161093DB00661
DiseaseTimothy syndrome (implicated_via_orthology)

CACNA1C CACNA1D CACNA1S

1.65e-0741033DOID:0060173 (implicated_via_orthology)
Diseaseautosomal recessive nonsyndromic deafness 16 (implicated_via_orthology)

STRC STRCP1

1.21e-0521032DOID:0110471 (implicated_via_orthology)
Diseaseresponse to olanzapine

CACNA1C HIVEP1 ADGRV1

1.82e-05151033GO_0097333
Diseaseeosinophil count

ERBB3 HIVEP1 ZNF577 ADAMTS4 KDM4C CYP21A2 PSMD2 RRBP1 ERN2 ITGB3 PTPRJ MED12L UBAC2 DLST PLEC IL4R

5.70e-05148810316EFO_0004842
Diseasealanine measurement

CYP21A2 ADCY5 PROX2 DLST

2.39e-04861034EFO_0009765
Diseasegrapefruit juice consumption measurement

CACNA1C PCLO

2.51e-0471032EFO_0010094
DiseaseX-16935 measurement

ACOT6 ACOT2

2.51e-0471032EFO_0800763
DiseaseDuchenne muscular dystrophy (implicated_via_orthology)

CACNA1C CACNA1D CACNA1S

2.71e-04361033DOID:11723 (implicated_via_orthology)
DiseaseX-24747 measurement

ACOT6 ACOT2

3.33e-0481032EFO_0022135
DiseaseSudden Cardiac Death

CACNA1C TMEM43

3.33e-0481032C0085298
DiseaseCongenital small ears

POLR1D FREM2 FGFR3

4.00e-04411033C0152423
Diseaseacoustic startle blink response measurement

CACNA1C PARP14

4.28e-0491032EFO_0006875
DiseaseColon Carcinoma

ERBB3 PTPRJ

4.28e-0491032C0699790
DiseaseX-17653 measurement

ACOT6 ACOT2

4.28e-0491032EFO_0800783
DiseaseX-11308 measurement

ACOT6 ACOT2

6.50e-04111032EFO_0800693
DiseaseColorectal Carcinoma

COL7A1 FPGS DSCAML1 PAX8 ABCC8 ADAMTS18 FGFR3 ACTL9 LONRF2

7.98e-047021039C0009402
DiseaseDisorder of eye

COL11A2 CDHR1 WT1 ADGRV1 FREM2

9.04e-042121035C0015397
Diseaseundecenoylcarnitine (C11:1) measurement

ACOT6 ACOT2

9.18e-04131032EFO_0800588
DiseaseNeoplasm of uncertain or unknown behavior of bladder

ERBB3 FGFR3

1.23e-03151032C0496930
DiseaseBenign neoplasm of bladder

ERBB3 FGFR3

1.23e-03151032C0154017
DiseaseCarcinoma in situ of bladder

ERBB3 FGFR3

1.23e-03151032C0154091
DiseaseX-17654 measurement

ACOT6 ACOT2

1.23e-03151032EFO_0800784
Diseasealcohol consumption measurement

CACNA1C CACNA1D KDM4C CYP21A2 PCLO PSMD2 ADGRV1 SLC45A4 PTPRJ SLC2A13 BCAR3 PPP6R3

1.31e-03124210312EFO_0007878
Diseasenervousness

PTPRJ DLST

1.40e-03161032NCIT_C74532
Diseasebody weight

CACNA1C HIVEP1 MOGAT1 CYP21A2 ADGRV1 ADCY5 MEX3A PTPRJ PTPRN PAX8 GUSB ABCC8

1.49e-03126110312EFO_0004338
DiseaseLimb Deformities, Congenital

CACNA1C COL11A2

1.59e-03171032C0206762
Diseaseserum non-albumin protein measurement

ADAMTS4 CYP21A2 ITGB3 SLC45A4 LONRF2 IL4R

1.70e-033611036EFO_0004568
DiseaseCarcinoma of bladder

ERBB3 FGFR3

1.78e-03181032C0699885
Diseaseworry measurement

HIVEP1 PROX2 DLST SLC38A3

2.11e-031541034EFO_0009589
Diseasecitrulline measurement

CYP21A2 HMCN2

2.20e-03201032EFO_0009777
Diseasenon-small cell lung carcinoma

CYP21A2 DLST ADGRF3

2.32e-03751033EFO_0003060
Diseaseelectrocardiography

CACNA1C HIVEP1 WT1 HMCN2 USP40 ADAMTS18 PLEC

2.61e-035301037EFO_0004327
DiseaseNonsyndromic Deafness

COL11A2 ADGRV1 STRC

2.89e-03811033C3711374
DiseaseCleft Palate

COL11A2 INTS1 FGFR3

2.89e-03811033C0008925
DiseaseColorectal Neoplasms

COL7A1 FPGS PAX8 ABCC8 FGFR3

2.91e-032771035C0009404
Diseasestomach carcinoma (is_marker_for)

ERBB3 KDM4C

3.17e-03241032DOID:5517 (is_marker_for)
Diseaseneutrophil measurement

PSMD2 RRBP1 SLCO5A1 PLEC

3.49e-031771034EFO_0803548

Protein segments in the cluster

PeptideGeneStartEntry
IAVRGLAPEQPVTLR

ACOT1

21

Q86TX2
TLPLPNLRVVRGTQV

ERBB3

96

P21860
LPLRVAAATNRVVAP

BACE2

31

Q9Y5Z0
GLAPLRVPISITIIQ

ADGRF3

411

Q8IZF5
NLQLVGPRGIFRVVP

CDHR1

396

Q96JP9
RLILQIGRGTVVPEP

ALG13

36

Q9NP73
VIRQGEIFLLPARVP

HAAO

76

P46952
GAIIFQPINRTVPLR

BCAR3

246

O75815
RLAQAIGIPEPRVQI

DUX4L4

51

P0CJ87
QPPEIGNISIVRIII

ADGRV1

4376

Q8WXG9
PELTLVQPLRSGIVV

ACTL9

106

Q8TC94
VRIAVRGLAPEQPVT

ACOT2

81

P49753
IAVRGLAPEQPVTLR

ACOT6

21

Q3I5F7
RLAQAIGIPEPRVQI

DUX4L6

51

P0CJ89
AVQVVGLLLPQPRSA

ADCY5

311

O95622
PPVLDVRTLLQRGLQ

CDAN1

671

Q8IWY9
PVVLIPAGARSIEIQ

ADAMTS18

766

Q8TE60
RVLPPGQTAPLRVIS

ADNP2

496

Q6IQ32
VNGRPLPEVVRQRIV

PAX8

21

Q06710
ERQPQARVVVLGLLP

PAFAH1B3

126

Q15102
RLSPVVIRRIQVPQD

CDRT15

36

Q96T59
IHTVVGRPIPVRQTL

MOGAT1

281

Q96PD6
NLNVSEPRAVIPGLR

PTPRJ

411

Q12913
VGQARPLLQVTSPVL

PTPRN

66

Q16849
PLIARLPTSVQGRVL

MED12L

1416

Q86YW9
VLSAIGPIQRPAREV

MAGEC3

571

Q8TD91
RLAQAIGIPEPRVQI

DUX4

51

Q9UBX2
PEVPGITVRVLQALA

INTS1

1396

Q8N201
PARIGRAVRPIEVTQ

KLK14

136

Q9P0G3
QLVVTLPVVLPAARR

DNAAF2

341

Q9NVR5
PQRVRSLEGIPLAQV

HERC3

181

Q15034
LFTLRVQVPPRIAGL

HMCN2

2936

Q8NDA2
RELPVEVRQALGQVP

ERN2

861

Q76MJ5
PGESVVIRIPVIRQG

FREM2

2266

Q5SZK8
NATIAEVLRLRPVVP

CYP21A2

346

P08686
RLAQAIGIPEPRVQI

DUX4L3

51

P0CJ86
SLPISQSRGRIPIVA

PCLO

4341

Q9Y6V0
PILTLRVPRAQAVVG

FCRL5

566

Q96RD9
LLTVVRTRPGLQAPL

COL11A2

86

P13942
PERTQIDVGRIPLQR

KDM4C

791

Q9H3R0
PARPQVRRVNVVLSG

LONRF2

171

Q1L5Z9
AAPGLLRRVVVPVLV

NKX2-8

161

O15522
LRRVVVPVLVRDGQP

NKX2-8

166

O15522
VLRNPAVALRGVVPD

IQGAP3

631

Q86VI3
TQLAPQRVRVTLRPG

ITGB7

121

P26010
QVPLIGRLLRAVQPV

LPCAT2

171

Q7L5N7
GRLLRAVQPVLVSRV

LPCAT2

176

Q7L5N7
VATPRGLVVPVIRNV

DLST

321

P36957
AALPRRVQLQAGVPV

PROX2

286

Q3B8N5
RVVRALDAVALPQPV

PGR

646

P06401
IRPAATLVNEGRPRI

PARP14

366

Q460N5
VSPRRNDIISVPGIQ

CCDC181

76

Q5TID7
PSIRNPVSLVVTRLV

ADAMTS4

256

O75173
PVQRRLEVPVSGLRS

CEFIP

121

Q711Q0
PPVILEQRRQVIVGT

IGSF10

1841

Q6WRI0
IPNPARSRLVAIIIQ

IL4R

266

P24394
VLRPLRLVSGVPSLQ

CACNA1C

241

Q13936
LVIRPPIISGQIVNL

DOCK6

786

Q96HP0
RPLRLVSGVPSLQVV

CACNA1S

171

Q13698
DVVTLLRRIQPPLGF

CACNA1S

1421

Q13698
ATVSRERQLIVRVPP

DSCAML1

676

Q8TD84
VIAAIVLAITLRRPG

FAM151A

26

Q8WW52
LGLVSPAQLRVFPVR

ATPAF1

36

Q5TC12
LVQVGPLPSRLRITI

GUSB

156

P08236
NLPARRVIIRTPIFG

POLQ

451

O75417
RLAQAIGIPEPRVQI

DUX4L9

51

Q6RFH8
RLAQAIGIPEPRVQI

DUX4L7

51

P0CJ90
NRSVAVTLRLRGVPP

IDUA

451

P35475
VTQVSPQRIALRLRP

ITGB3

106

P05106
VRERIRINGQPISPE

FPGS

136

Q05932
TAPEPVGRVSRLQIL

COL7A1

771

Q02388
LGRRAFIPLPSAVVQ

SDR39U1

236

Q9NRG7
LVPSERVLVGPQRLQ

FGFR3

81

P22607
RLAQAIGIPEPRVQI

DUX4L5

51

P0CJ88
RPLRLVSGVPSLQVV

CACNA1D

246

Q01668
LFVPTPVQRGALVLI

PHYHD1

226

Q5SRE7
IAEVSPPNLRGRLVT

SLC2A13

196

Q96QE2
NLRIQTRGTLPAVEP

POLR1D

81

P0DPB6
AIIERVRLPVNVLVP

GAREM2

256

Q75VX8
GLALVPILVARTRVP

TMEM43

381

Q9BTV4
AVTLTVPIVLFPVRR

SLC38A3

376

Q99624
RSIPRPEVQALGLTV

PLEKHG4

236

Q58EX7
VTLTVPVVLFPIRRA

SLC38A5

346

Q8WUX1
ELRPLPVSVRVGQAV

PSMD2

836

Q13200
TPPTVGQRSQLRVVI

SLCO5A1

611

Q9H2Y9
LPRPQLRSVVGIGVS

SHPK

76

Q9UHJ6
RAVNPIIPPTGLVRA

POLR3F

271

Q9H1D9
GLSPQTLQAIPRRVL

STRC

1061

Q7RTU9
PPQARGLLTEIRAVV

STK17A

36

Q9UEE5
DGIPTLSNITIRIPR

ABCC8

691

Q09428
PNRQPIGIVLTVLGV

SLC45A4

151

Q5BKX6
SVRQFTLRVRVPGPV

SWI5

41

Q1ZZU3
SRVREFVGQLVAPLP

VWA1

51

Q6PCB0
NVTVLLREPVRAPAV

RRBP1

91

Q9P2E9
APGVVELVLIPLRQR

SPEF1

96

Q9Y4P9
VAPALPGQVTIRVRV

MEX3A

216

A1L020
PGQVTIRVRVPYRVV

MEX3A

221

A1L020
PRVTGVVLFRQLAPR

SOD3

76

P08294
LRRPVNQVVLADAPV

ROBO3

261

Q96MS0
VAVRLQEPIVLGPRT

ROBO3

671

Q96MS0
SLQQIVIPERVLGTP

nan

71

Q6ZSR6
RLVGRNVVIVEQPFP

ZNF577

431

Q9BSK1
GIQDVRRVPGVAPTL

WT1

296

P19544
EAVRRQLLPQGIVPA

TMCO6

181

Q96DC7
EIVPASLQRVRRPVA

PLEC

91

Q15149
VVPTRIPAIVSLSRG

ZNHIT2

191

Q9UHR6
PFRGRARPLDQVLVI

ZCCHC18

296

P0CG32
GLSPQTLQAIPRRVL

STRCP1

1061

A6NGW2
PRVQVAQILGPLSIT

UBAC2

146

Q8NBM4
VLVRLIPAPRGTGIV

RPS2

191

P15880
LDPPVGNTRLNVIRL

PPP6R3

336

Q5H9R7
PQDVLLRTQVRIPGE

USP40

1066

Q9NVE5
RGPLVRQISLNIAPD

HIVEP1

1426

P15822
GERPVNARVVRVAPL

nan

81

Q8N402
LSIRVIPDGPTRALQ

VPS13D

3776

Q5THJ4
RLAQAIGIPEPRVQI

DUX4L2

51

P0CJ85
DRILEINGTPIRNVP

LIMK1

221

P53667
PRVIVGTIRPRVIVG

RAB34

16

P0DI83