Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyBiologicalProcessmulti-pass transmembrane protein insertion into ER membrane

NOMO1 NOMO2 NOMO3

2.77e-0591453GO:0160063
GeneOntologyBiologicalProcesscellular response to caffeine

CACNA1S SELENON RYR1

5.39e-05111453GO:0071313
GeneOntologyBiologicalProcesscalcium ion transport

CACNA1S TRPC5 DBI EFHB SELENON RYR1 AHNAK AGT ASPH TRPV3 DMD ATP2B2 ATP2B4

6.45e-0550914513GO:0006816
GeneOntologyBiologicalProcesscalcium ion transmembrane transport

CACNA1S TRPC5 DBI SELENON RYR1 AHNAK ASPH TRPV3 DMD ATP2B2 ATP2B4

1.06e-0439214511GO:0070588
GeneOntologyBiologicalProcesscellular response to purine-containing compound

CACNA1S SELENON RYR1

1.17e-04141453GO:0071415
GeneOntologyBiologicalProcessglial cell development

ITGB4 ZEB2 PRX SIRT2 AGT LRP1 DMD

1.24e-041571457GO:0021782
GeneOntologyBiologicalProcessintracellular chemical homeostasis

CACNA1S COX19 HK2 ACO1 TRPC5 HKDC1 DBI SELENON RYR1 ARRB1 AGT ASPH LRP1 ALAS2 DMD ATP2B2 ATP2B4

1.27e-0486614517GO:0055082
GeneOntologyBiologicalProcesspositive regulation of DNA-templated DNA replication

ATRX INO80 CDK2

1.46e-04151453GO:2000105
GeneOntologyBiologicalProcesscalcium ion transmembrane import into cytosol

CACNA1S DBI SELENON RYR1 ASPH TRPV3 DMD ATP2B4

1.53e-042171458GO:0097553
GeneOntologyBiologicalProcessmembrane biogenesis

SELENON RFTN1 SIRT2 PTPRD NRXN2

1.64e-04731455GO:0044091
GeneOntologyBiologicalProcesschemical homeostasis

CACNA1S COX19 HK2 ACO1 TRPC5 HECTD4 HKDC1 APOB DBI SELENON RYR1 ABCB4 ARRB1 AGT ASPH LRP1 ALAS2 DMD ATP2B2 ATP2B4 UNC80

1.75e-04124914521GO:0048878
GeneOntologyBiologicalProcessneuron cell-cell adhesion

NRXN3 NRXN2 ASTN1

1.78e-04161453GO:0007158
GeneOntologyCellularComponentmulti-pass translocon complex

NOMO1 NOMO2 NOMO3

2.77e-0591473GO:0160064
GeneOntologyCellularComponentER membrane insertion complex

NOMO1 NOMO2 NOMO3

1.17e-04141473GO:0072379
GeneOntologyCellularComponentpresynapse

DOC2A TRPC5 SLC35G2 DBI PDLIM5 SLC6A11 NRXN3 PTPRD NRXN2 PIK3C3 CADPS SLC6A5 SENP6 RIMS1 DMD ATP2B2 ATP2B4

1.69e-0488614717GO:0098793
GeneOntologyCellularComponentcontractile muscle fiber

CACNA1S MYL2 DBI PDLIM5 RYR1 AHNAK MMP2 DMD ATP2B4

2.18e-042901479GO:0043292
GeneOntologyCellularComponentpresynaptic active zone membrane

NRXN3 NRXN2 RIMS1 ATP2B2 ATP2B4

2.24e-04781475GO:0048787
GeneOntologyCellularComponentextrinsic component of membrane

DOC2A RYR1 JAK1 PIK3C2G PIK3C3 CADPS RIMS1 CDH18

2.28e-042301478GO:0019898
GeneOntologyCellularComponentmyofibril

CACNA1S MYL2 PDLIM5 RYR1 AHNAK MMP2 DMD ATP2B4

7.13e-042731478GO:0030016
GeneOntologyCellularComponentmCRD-mediated mRNA stability complex

PABPC1 PABPC3

7.23e-0461472GO:0106002
GeneOntologyCellularComponentheterochromatin

ATRX IKZF1 SIRT2 TNKS1BP1 KDM4B

7.40e-041011475GO:0000792
GeneOntologyCellularComponentpresynaptic membrane

SLC6A11 NRXN3 PTPRD NRXN2 SLC6A5 RIMS1 ATP2B2 ATP2B4

7.83e-042771478GO:0042734
GeneOntologyCellularComponentsynaptic membrane

ITGB4 SLC6A11 ARRB1 NRXN3 PTPRD NRXN2 SLC6A5 LRP1 RIMS1 DMD ATP2B2 ATP2B4

8.71e-0458314712GO:0097060
GeneOntologyCellularComponentGABA-ergic synapse

SLC6A11 NRXN3 PIK3C3 RIMS1 DMD ATP2B2

1.08e-031641476GO:0098982
HumanPhenoAbnormal blood carbon dioxide level

CACNA1S MYL2 SELENON RYR1

4.15e-0614434HP:0500164
HumanPhenoHypercapnia

CACNA1S MYL2 SELENON RYR1

4.15e-0614434HP:0012416
DomainDUF2012

NOMO1 NOMO2 NOMO3

1.82e-0641453PF09430
DomainDUF2012

NOMO1 NOMO2 NOMO3

1.82e-0641453IPR019008
DomainRibosomal_S6_kinase_II

RPS6KA5 RPS6KA2 RPS6KA3

9.01e-0661453IPR016239
DomainCarb-bd-like_fold

NOMO1 NOMO2 NOMO3

2.49e-0581453IPR013784
DomainCarboxyPept_regulatory_dom

NOMO1 NOMO2 NOMO3

1.24e-04131453IPR014766
Domain-

NOMO1 NOMO2 NOMO3

1.24e-041314532.60.40.1120
DomainTPR-contain_dom

RANBP2 ASPH VPS13A PDCD11 ZC3H7B DNAJC3 EDRF1

1.72e-041501457IPR013026
Domain-

RANBP2 CFAP54 ASPH PDCD11 IFT122 ZC3H7B DNAJC3 EDRF1

2.16e-0420714581.25.40.10
DomainCarboxyPept-like_regulatory

NOMO1 NOMO2 NOMO3

2.88e-04171453IPR008969
DomainATP_Ca_trans_C

ATP2B2 ATP2B4

3.56e-0441452IPR022141
DomainATP_Ca_trans_C

ATP2B2 ATP2B4

3.56e-0441452PF12424
DomainP-type_ATPase_IIB

ATP2B2 ATP2B4

3.56e-0441452IPR006408
DomainTPR-like_helical_dom

RANBP2 CFAP54 ASPH PDCD11 IFT122 ZC3H7B DNAJC3 EDRF1

4.79e-042331458IPR011990
DomainPolyA

PABPC1 PABPC3

5.89e-0451452SM00517
DomainHexokinase_2

HK2 HKDC1

5.89e-0451452PF03727
Domain-

PABPC1 PABPC3

5.89e-04514521.10.1900.10
DomainPABP

PABPC1 PABPC3

5.89e-0451452PF00658
DomainPABP_1234

PABPC1 PABPC3

5.89e-0451452IPR006515
DomainHexokinase_BS

HK2 HKDC1

5.89e-0451452IPR019807
DomainHexokinase_C

HK2 HKDC1

5.89e-0451452IPR022673
DomainHexokinase_N

HK2 HKDC1

5.89e-0451452IPR022672
DomainHexokinase_1

HK2 HKDC1

5.89e-0451452PF00349
DomainPABC

PABPC1 PABPC3

5.89e-0451452PS51309
DomainHEXOKINASE_2

HK2 HKDC1

5.89e-0451452PS51748
DomainPABP_HYD

PABPC1 PABPC3

5.89e-0451452IPR002004
DomainHEXOKINASE_1

HK2 HKDC1

5.89e-0451452PS00378
DomainC2

DOC2A PIK3C2G PIK3C3 CADPS RIMS1 RASAL1

7.05e-041371456SM00239
DomainHexokinase

HK2 HKDC1

8.80e-0461452IPR001312
DomainSyndecan

NRXN3 NRXN2

1.23e-0371452PF01034
DomainSyndecan/Neurexin_dom

NRXN3 NRXN2

1.23e-0371452IPR027789
DomainHelicase_C

ERCC3 ATRX CHD1L INO80 DDX46

1.48e-031071455PF00271
DomainHELICc

ERCC3 ATRX CHD1L INO80 DDX46

1.48e-031071455SM00490
DomainHelicase_C

ERCC3 ATRX CHD1L INO80 DDX46

1.55e-031081455IPR001650
DomainHELICASE_CTER

ERCC3 ATRX CHD1L INO80 DDX46

1.61e-031091455PS51194
DomainHELICASE_ATP_BIND_1

ERCC3 ATRX CHD1L INO80 DDX46

1.61e-031091455PS51192
DomainDEXDc

ERCC3 ATRX CHD1L INO80 DDX46

1.61e-031091455SM00487
DomainPI3K_C2

PIK3C2G PIK3C3

1.63e-0381452SM00142
DomainPI3K_C2_dom

PIK3C2G PIK3C3

1.63e-0381452IPR002420
DomainPI3K_C2

PIK3C2G PIK3C3

1.63e-0381452PF00792
DomainPI3K_C2

PIK3C2G PIK3C3

1.63e-0381452PS51547
DomainHelicase_ATP-bd

ERCC3 ATRX CHD1L INO80 DDX46

1.68e-031101455IPR014001
DomainC2_dom

DOC2A PIK3C2G PIK3C3 CADPS RIMS1 RASAL1

1.78e-031641456IPR000008
DomainEF-hand-dom_pair

CACNA1S MYL2 EFHB SELENON RYR1 S100P DMD MYL10

1.83e-032871458IPR011992
DomainTPR_REGION

RANBP2 ASPH VPS13A ZC3H7B DNAJC3 EDRF1

1.84e-031651456PS50293
DomainTPR

RANBP2 ASPH VPS13A ZC3H7B DNAJC3 EDRF1

1.84e-031651456PS50005
DomainSNF2_N

ATRX CHD1L INO80

1.93e-03321453IPR000330
DomainSNF2_N

ATRX CHD1L INO80

1.93e-03321453PF00176
DomainPI3Ka

PIK3C2G PIK3C3

2.08e-0391452PF00613
DomainPI3Ka

PIK3C2G PIK3C3

2.08e-0391452SM00145
Domain-

PIK3C2G PIK3C3

2.08e-03914521.25.40.70
DomainPI_Kinase

PIK3C2G PIK3C3

2.59e-03101452IPR015433
DomainMacro_dom

CHD1L PARP9

2.59e-03101452IPR002589
DomainPInositide-3_kin_accessory_dom

PIK3C2G PIK3C3

2.59e-03101452IPR001263
DomainMACRO

CHD1L PARP9

2.59e-03101452PS51154
DomainPIK_HELICAL

PIK3C2G PIK3C3

2.59e-03101452PS51545
DomainClathrin_mu

AP1M2 AP5M1

2.59e-03101452IPR001392
DomainPkinase_C

RPS6KA5 RPS6KA2 RPS6KA3

2.94e-03371453IPR017892
DomainAdap_comp_sub

AP1M2 AP5M1

3.14e-03111452PF00928
DomainKinase-like_dom

ANKK1 RPS6KA5 RPS6KA2 RPS6KA3 JAK1 PIK3C2G PIK3C3 TESK2 BUB1 DMD CDK2

3.40e-0354214511IPR011009
DomainC2

DOC2A PIK3C2G CADPS RIMS1 RASAL1

3.58e-031311455PF00168
DomainPkinase_C

RPS6KA5 RPS6KA2 RPS6KA3

4.22e-03421453PF00433
DomainMHD

AP1M2 AP5M1

4.41e-03131452PS51072
DomainMHD

AP1M2 AP5M1

4.41e-03131452IPR028565
DomainEF-hand_6

MYL2 MYL10

4.41e-03131452PF13405
DomainC2

DOC2A PIK3C2G CADPS RIMS1 RASAL1

5.04e-031421455PS50004
DomainNeurexin-like

NRXN3 NRXN2

5.12e-03141452IPR003585
Domain4.1m

NRXN3 NRXN2

5.12e-03141452SM00294
DomainPI3/4_kinase_CS

PIK3C2G PIK3C3

5.88e-03151452IPR018936
Domain-

DOC2A PIK3C2G PIK3C3 RIMS1 RASAL1

5.99e-0314814552.60.40.150
Domain-

PIK3C2G PIK3C3

6.69e-031614521.10.1070.11
DomainATPase_P-typ_TM_dom

ATP2B2 ATP2B4

6.69e-03161452IPR023298
DomainPI3Kc

PIK3C2G PIK3C3

6.69e-03161452SM00146
Domain-

ATP2B2 ATP2B4

6.69e-031614521.20.1110.10
DomainPoly(ADP-ribose)pol_cat_dom

PARP6 PARP9

7.54e-03171452IPR012317
DomainPARP_CATALYTIC

PARP6 PARP9

7.54e-03171452PS51059
DomainATPase_P-typ_cation-transptr_C

ATP2B2 ATP2B4

7.54e-03171452IPR006068
DomainCation_ATPase_C

ATP2B2 ATP2B4

7.54e-03171452PF00689
DomainPARP

PARP6 PARP9

7.54e-03171452PF00644
Domain-

PARP6 PARP9

7.54e-031714523.90.228.10
PathwayREACTOME_CREB_PHOSPHORYLATION

RPS6KA5 RPS6KA2 RPS6KA3

1.63e-0571113M27096
PathwayREACTOME_CREB_PHOSPHORYLATION

RPS6KA5 RPS6KA2 RPS6KA3

1.63e-0571113MM14784
Pubmed

In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.

DOC2A KNTC1 PTBP3 STRN3 RANBP2 WBP11 ATRX FBF1 HKDC1 APOB PRPF8 KLF4 PABPC1 ZEB2 PRX ABCB4 RFTN1 ARRB1 NRXN3 PABPC3 AHNAK VPS13A IFT122 ALAS2 RIMS1 DMD PSPC1 ATP2B2 DNAJC3 BAHCC1

5.53e-1314421493035575683
Pubmed

Recurrent NOMO1 Gene Deletion Is a Potential Clinical Marker in Early-Onset Colorectal Cancer and Is Involved in the Regulation of Cell Migration.

NOMO1 NOMO2 NOMO3

7.71e-083149336011023
Pubmed

Silencing of nodal modulator 1 inhibits the differentiation of P19 cells into cardiomyocytes.

NOMO1 NOMO2 NOMO3

7.71e-083149325576386
Pubmed

Establishment of a conditional Nomo1 mouse model by CRISPR/Cas9 technology.

NOMO1 NOMO2 NOMO3

3.07e-074149331833031
Pubmed

A locus for autosomal recessive pseudoxanthoma elasticum, with penetrance of vascular symptoms in carriers, maps to chromosome 16p13.1.

NOMO1 NOMO2 NOMO3

3.07e-07414939267806
Pubmed

Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.

DCHS2 WBP11 ATRX ACO1 TAF1C HECTD4 ADNP2 PRPF8 ZEB2 PDLIM5 JAK1 ARRB1 PTPRD NOMO2 CADPS HECTD2 LRP1 SENP6 ASTN1 IFT122

6.60e-0712851492035914814
Pubmed

Identification and functional characterization of transcriptional activators in human cells.

KNTC1 ADNP2 ZEB2 ZNF518A KDM2A IFT122 MGA DNAJC3 KDM4B CDK2 BAHCC1

1.29e-063981491135016035
Pubmed

Perturbation of the mutated EGFR interactome identifies vulnerabilities and resistance mechanisms.

RPS6KA3 AP1M2 APOB ITGB4 PTPRD AIFM1 AHNAK VPS13A ATP2B4

1.75e-06256149924189400
Pubmed

The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.

STRN3 RANBP2 ERCC3 ATRX TAF1C SRP54 INO80 KLF4 EMSY NOMO1 RFTN1 DDX46 ARRB1 RPL7L1 ASPH PDCD11 CEP131 ZC3H7B PSPC1 EDRF1 MAN1B1

1.78e-0614971492131527615
Pubmed

HDLBP Promotes Hepatocellular Carcinoma Proliferation and Sorafenib Resistance by Suppressing Trim71-dependent RAF1 Degradation.

PTBP3 WBP11 ERCC3 RPS6KA3 TAF1C SRP54 APOB CHD1L PRPF8 PABPC1 PDLIM5 S100P DDX46 AIFM1 AHNAK ASPH PDCD11 CEP131 PSPC1 ATP2B4

1.78e-0613711492036244648
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

FBF1 HECTD4 INO80 DDX46 ATG4B NRXN3 NRXN2 SENP6 PDCD11 TNKS1BP1 ZC3H7B KDM4B

3.26e-065291491214621295
Pubmed

Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.

STRN3 RANBP2 WBP11 RPS6KA2 HECTD4 PABPC1 ZEB2 EMSY PTPRD PABPC3 LRP1 CEP131 RIMS1 MGA ATP2B4 RASAL1

4.16e-069631491628671696
Pubmed

Combinatorial expression of neurexins and LAR-type phosphotyrosine phosphatase receptors instructs assembly of a cerebellar circuit.

NRXN3 PTPRD NRXN2

4.25e-068149337591863
Pubmed

Over-expression of Grhl2 causes spina bifida in the Axial defects mutant mouse.

GRHL2 PABPC1 PABPC3

4.25e-068149321262862
Pubmed

Nicalin and its binding partner Nomo are novel Nodal signaling antagonists.

NOMO1 NOMO2 NOMO3

4.25e-068149315257293
Pubmed

Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.

RANBP2 ERCC3 HK2 TAF1C ADNP2 SRP54 CHD1L RRM2 PRPF8 PABPC1 SMG8 ATG4B RPL7L1 AIFM1 AHNAK ASPH PDCD11 KDM2A MGA

5.71e-0613531491929467282
Pubmed

Substrate-driven assembly of a translocon for multipass membrane proteins.

NOMO1 NOMO2 NOMO3

6.35e-069149336261522
Pubmed

Increased muscle stress-sensitivity induced by selenoprotein N inactivation in mouse: a mammalian model for SEPN1-related myopathy.

CACNA1S SELENON RYR1

6.35e-069149321858002
Pubmed

Distinct transcriptomic changes in E14.5 mouse skeletal muscle lacking RYR1 or Cav1.1 converge at E18.5.

CACNA1S MYL2 KLF4 RYR1

7.07e-0629149429543863
Pubmed

AAV-mediated intramuscular delivery of myotubularin corrects the myotubular myopathy phenotype in targeted murine muscle and suggests a function in plasma membrane homeostasis.

CACNA1S RYR1 DMD

9.05e-0610149318434328
Pubmed

An FBXW7-ZEB2 axis links EMT and tumour microenvironment to promote colorectal cancer stem cells and chemoresistance.

ZEB2 NOMO1 NOMO2 NOMO3

1.20e-0533149430783098
Pubmed

An ER translocon for multi-pass membrane protein biogenesis.

NOMO1 NOMO2 NOMO3

1.24e-0511149332820719
Pubmed

Paralog knockout profiling identifies DUSP4 and DUSP6 as a digenic dependence in MAPK pathway-driven cancers.

ENPP6 STRN3 FBXW10 HK2 RPS6KA5 RPS6KA2 RPS6KA3 LRP1 KDM2A MMP2 PSPC1 ATP2B4 CDK2

1.69e-057301491334857952
Pubmed

Ca2+ influx through alpha1S DHPR may play a role in regulating Ca2+ release from RyR1 in skeletal muscle.

CACNA1S RYR1

1.82e-052149212954602
Pubmed

Identification of a Klf4-dependent upstream repressor region mediating transcriptional regulation of the myocardin gene in human smooth muscle cells.

KLF4 MYOCD

1.82e-052149224060351
Pubmed

Investigating the genetic susceptibility to exertional heat illness.

CACNA1S RYR1

1.82e-052149232054689
Pubmed

Effects of conformational peptide probe DP4 on bidirectional signaling between DHPR and RyR1 calcium channels in voltage-clamped skeletal muscle fibers.

CACNA1S RYR1

1.82e-052149221575570
Pubmed

Muscle CD31(-) CD45(-) side population cells promote muscle regeneration by stimulating proliferation and migration of myoblasts.

MMP2 DMD

1.82e-052149218669618
Pubmed

Multiple regions of RyR1 mediate functional and structural interactions with alpha(1S)-dihydropyridine receptors in skeletal muscle.

CACNA1S RYR1

1.82e-052149212496092
Pubmed

Clinical utility gene card for: malignant hyperthermia.

CACNA1S RYR1

1.82e-052149221248738
Pubmed

Exome sequencing reveals novel rare variants in the ryanodine receptor and calcium channel genes in malignant hyperthermia families.

CACNA1S RYR1

1.82e-052149224013571
Pubmed

Analysis of the entire ryanodine receptor type 1 and alpha 1 subunit of the dihydropyridine receptor (CACNA1S) coding regions for variants associated with malignant hyperthermia in Australian families.

CACNA1S RYR1

1.82e-052149225735680
Pubmed

Functional expression of transgenic 1sDHPR channels in adult mammalian skeletal muscle fibres.

CACNA1S RYR1

1.82e-052149221262876
Pubmed

The promoter of the Poly(A) binding protein 2 (Pabp2) retroposon is derived from the 5'-untranslated region of the Pabp1 progenitor gene.

PABPC1 PABPC3

1.82e-052149210534404
Pubmed

Microdiversity of human-plasma-membrane calcium-pump isoform 2 generated by alternative RNA splicing in the N-terminal coding region.

ATP2B2 ATP2B4

1.82e-05214921313367
Pubmed

Increasing the number of diagnostic mutations in malignant hyperthermia.

CACNA1S RYR1

1.82e-052149219191329
Pubmed

Malignant-hyperthermia susceptibility is associated with a mutation of the alpha 1-subunit of the human dihydropyridine-sensitive L-type voltage-dependent calcium-channel receptor in skeletal muscle.

CACNA1S RYR1

1.82e-05214929199552
Pubmed

Plasma membrane calcium pump (PMCA) isoform 4 is targeted to the apical membrane by the w-splice insert from PMCA2.

ATP2B2 ATP2B4

1.82e-052149222252018
Pubmed

β4 integrin marks interstitial myogenic progenitor cells in adult murine skeletal muscle.

ITGB4 DMD

1.82e-052149222205679
Pubmed

Kruppel-like factor 4 protein regulates isoproterenol-induced cardiac hypertrophy by modulating myocardin expression and activity.

KLF4 MYOCD

1.82e-052149225100730
Pubmed

Plasma membrane Ca²⁺-ATPases can shape the pattern of Ca²⁺ transients induced by store-operated Ca²⁺ entry.

ATP2B2 ATP2B4

1.82e-052149225690014
Pubmed

Nucleotide sequence of a mouse testis poly(A) binding protein cDNA.

PABPC1 PABPC3

1.82e-05214921630930
Pubmed

Four calcium signaling pathway-related genes were upregulated in microcystic adnexal carcinoma: transcriptome analysis and immunohistochemical validation.

CACNA1S RYR1

1.82e-052149235509066
Pubmed

Reciprocal regulation of integrin β4 and KLF4 promotes gliomagenesis through maintaining cancer stem cell traits.

KLF4 ITGB4

1.82e-052149230658712
Pubmed

Developmental expression of poly(A) binding protein mRNAs during spermatogenesis in the mouse.

PABPC1 PABPC3

1.82e-05214927893484
Pubmed

Characterization of two cytoplasmic poly(A)-binding proteins, PABPC1 and PABPC2, in mouse spermatogenic cells.

PABPC1 PABPC3

1.82e-052149219020299
Pubmed

Angiotensin II induces MMP 2 activity via FAK/JNK pathway in human endothelial cells.

AGT MMP2

1.82e-052149219338750
Pubmed

Fluorescence resonance energy transfer (FRET) indicates that association with the type I ryanodine receptor (RyR1) causes reorientation of multiple cytoplasmic domains of the dihydropyridine receptor (DHPR) α(1S) subunit.

CACNA1S RYR1

1.82e-052149223071115
Pubmed

TCN1 Deficiency Inhibits the Malignancy of Colorectal Cancer Cells by Regulating the ITGB4 Pathway.

TCN1 ITGB4

1.82e-052149235686504
Pubmed

Functional compensation for the loss of testis-specific poly(A)-binding protein, PABPC2, during mouse spermatogenesis.

PABPC1 PABPC3

1.82e-052149226971890
Pubmed

Comparison of pathogenicity prediction tools on missense variants in RYR1 and CACNA1S associated with malignant hyperthermia.

CACNA1S RYR1

1.82e-052149227147545
Pubmed

Levels of free PABP are limited by newly polyadenylated mRNA in early Spisula embryogenesis.

PABPC1 PABPC3

1.82e-052149210954604
Pubmed

Multiminicore Disease – RETIRED CHAPTER, FOR HISTORICAL REFERENCE ONLY

SELENON RYR1

1.82e-052149220301467
Pubmed

The alpha(1S) III-IV loop influences 1,4-dihydropyridine receptor gating but is not directly involved in excitation-contraction coupling interactions with the type 1 ryanodine receptor.

CACNA1S RYR1

1.82e-052149218556650
Pubmed

Distinct Components of Retrograde Ca(V)1.1-RyR1 Coupling Revealed by a Lethal Mutation in RyR1.

CACNA1S RYR1

1.82e-052149226910427
Pubmed

Selenoprotein N is required for ryanodine receptor calcium release channel activity in human and zebrafish muscle.

SELENON RYR1

1.82e-052149218713863
Pubmed

MEK, ERK, and p90RSK are present on mitotic tubulin in Swiss 3T3 cells: a role for the MAP kinase pathway in regulating mitotic exit.

RPS6KA2 RPS6KA3

1.82e-052149211495723
Pubmed

The mouse gene encoding the testis-specific isoform of Poly(A) binding protein (Pabp2) is an expressed retroposon: intimations that gene expression in spermatogenic cells facilitates the creation of new genes.

PABPC1 PABPC3

1.82e-05214929732454
Pubmed

Matrix metalloproteinase-2 ablation in dystrophin-deficient mdx muscles reduces angiogenesis resulting in impaired growth of regenerated muscle fibers.

MMP2 DMD

1.82e-052149221320869
Pubmed

Morphology and molecular composition of sarcoplasmic reticulum surface junctions in the absence of DHPR and RyR in mouse skeletal muscle.

CACNA1S RYR1

1.82e-052149212023238
Pubmed

Single nucleotide polymorphisms predict the change in left ventricular mass in response to antihypertensive treatment.

APOB AGT

1.82e-052149215614026
Pubmed

Dihydropyridine receptor gene expression in skeletal muscle from mdx and control mice.

CACNA1S DMD

1.82e-05214929540851
Pubmed

Next-generation Sequencing of RYR1 and CACNA1S in Malignant Hyperthermia and Exertional Heat Illness.

CACNA1S RYR1

1.82e-052149225658027
Pubmed

Quantitative reduction of RyR1 protein caused by a single-allele frameshift mutation in RYR1 ex36 impairs the strength of adult skeletal muscle fibres.

CACNA1S RYR1

1.82e-052149230689883
Pubmed

Elevated MMP2 abundance and activity in mdx mice are alleviated by prenatal taurine supplementation.

MMP2 DMD

1.82e-052149232208990
Pubmed

Inhibition of the ATR-CHK1 Pathway in Ewing Sarcoma Cells Causes DNA Damage and Apoptosis via the CDK2-Mediated Degradation of RRM2.

RRM2 CDK2

1.82e-052149231649026
Pubmed

RYR1 and CACNA1S genetic variants identified with statin-associated muscle symptoms.

CACNA1S RYR1

1.82e-052149230325262
Pubmed

Plasma membrane calcium-ATPase 2 and 4 in human breast cancer cell lines.

ATP2B2 ATP2B4

1.82e-052149216216224
Pubmed

Overlapping Activities of Two Neuronal Splicing Factors Switch the GABA Effect from Excitatory to Inhibitory by Regulating REST.

PARP6 NRXN3 CADPS ASPH RIMS1 ATP2B2

1.97e-05128149630995482
Pubmed

Maternal Transient Receptor Potential Vanilloid 6 (Trpv6) Is Involved In Offspring Bone Development.

TRPC5 RYR1 ATP2B2 ATP2B4

2.13e-0538149430786075
Pubmed

Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.

ATRX RPS6KA2 HECTD4 SRP54 CHD1L SELENON GRHL2 ARRB1 PIK3C3 PTPRR ANKAR ASPH LRP1 KDM2A IFT122 RIMS1 DNAJC3 MAN1B1 KDM4B

2.17e-0514891491928611215
Pubmed

Optimized fragmentation schemes and data analysis strategies for proteome-wide cross-link identification.

HK2 ATRX CHD1L DBI PRPF8 PABPC1 DDX46 AHNAK TNKS1BP1 DMD ATP2B2

2.22e-055381491128524877
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

DOC2A MON2 RPS6KA2 HECTD4 INO80 KLF4 ITGB4 RYR1 SIRT2 AHNAK PDCD11 TNKS1BP1 CEP131 ZC3H7B RASAL1 BAHCC1

2.28e-0511051491635748872
Pubmed

Identification of proximal SUMO-dependent interactors using SUMO-ID.

RANBP2 WBP11 ERCC3 SRP54 RRM2 EMSY AHNAK SENP6 TNKS1BP1 MGA

2.34e-054441491034795231
Pubmed

The contribution of rare and common variants in 30 genes to risk nicotine dependence.

ANKK1 NRXN3 NRXN2

2.71e-0514149325450229
Pubmed

Mitogen- and stress-activated protein kinase-1 (MSK1) is directly activated by MAPK and SAPK2/p38, and may mediate activation of CREB.

RPS6KA5 RPS6KA2 RPS6KA3

2.71e-051414939687510
Pubmed

Host cell interactome of HIV-1 Rev includes RNA helicases involved in multiple facets of virus production.

ERCC3 HK2 SRP54 PRPF8 PABPC1 PDCD11 PSPC1

3.18e-05206149722174317
Pubmed

Intact lipid rafts regulate HIV-1 Tat protein-induced activation of the Rho signaling and upregulation of P-glycoprotein in brain endothelial cells.

MYL2 ABCB4 MYL10

4.14e-0516149319794400
Pubmed

Dynamic regulation of sarcoplasmic reticulum Ca(2+) stores by stromal interaction molecule 1 and sarcolipin during muscle differentiation.

CACNA1S TRPC5 RYR1

5.01e-0517149322411552
Pubmed

Spinal neural tube closure depends on regulation of surface ectoderm identity and biomechanics by Grhl2.

MYL2 GRHL2 ZEB2

5.01e-0517149331171776
Pubmed

Comprehensive Interactome Mapping of the DNA Repair Scaffold SLX4 Using Proximity Labeling and Affinity Purification.

RANBP2 ATRX EMSY ZNF518A SENP6 PDCD11 MGA

5.11e-05222149737071664
Pubmed

Irisin Mediates Effects on Bone and Fat via αV Integrin Receptors.

HKDC1 SEC11C PRPF8 SELENON PABPC1 NOMO1 NOMO2 AIFM1 NT5DC2 PABPC3 AHNAK ASPH LRP1 MMP2 PSPC1 DNAJC3 NOMO3 MAN1B1

5.23e-0514511491830550785
Pubmed

N-Terminal Acetyltransferase Naa40p Whereabouts Put into N-Terminal Proteoform Perspective.

STRN3 RANBP2 ATRX SRP54 PRPF8 PABPC1 EMSY PDLIM5 SIRT2 DDX46 AHNAK SENP6 TNKS1BP1 CDK2

5.24e-059341491433916271
Pubmed

Conditional Knockout of Neurexins Alters the Contribution of Calcium Channel Subtypes to Presynaptic Ca2+ Influx.

NRXN3 NRXN2

5.45e-053149238891114
Pubmed

Embryonic Poly(A)-Binding Protein Is Required During Early Stages of Mouse Oocyte Development for Chromatin Organization, Transcriptional Silencing, and Meiotic Competence.

PABPC1 PABPC3

5.45e-053149226134869
Pubmed

Iron regulatory protein-1 protects against mitoferrin-1-deficient porphyria.

ACO1 ALAS2

5.45e-053149224509859
Pubmed

Human testis expresses a specific poly(A)-binding protein.

PABPC1 PABPC3

5.45e-053149211328870
Pubmed

Superovulation alters embryonic poly(A)-binding protein (Epab) and poly(A)-binding protein, cytoplasmic 1 (Pabpc1) gene expression in mouse oocytes and early embryos.

PABPC1 PABPC3

5.45e-053149225034140
Pubmed

Interplay between KLF4 and ZEB2/SIP1 in the regulation of E-cadherin expression.

KLF4 ZEB2

5.45e-053149223376074
Pubmed

Exome-wide association study identifies genetic polymorphisms of C12orf51, MYL2, and ALDH2 associated with blood lead levels in the general Korean population.

MYL2 HECTD4

5.45e-053149228212632
Pubmed

Increased matrix-metalloproteinase-2 and matrix-metalloproteinase-9 expression in the brain of dystrophic mdx mouse.

MMP2 DMD

5.45e-053149216650610
Pubmed

MicroRNA-29a promotes colorectal cancer metastasis by regulating matrix metalloproteinase 2 and E-cadherin via KLF4.

KLF4 MMP2

5.45e-053149224281002
Pubmed

Angiotensin II Downregulates MicroRNA-145 to Regulate Kruppel-like Factor 4 and Myocardin Expression in Human Coronary Arterial Smooth Muscle Cells under High Glucose Conditions.

KLF4 MYOCD

5.45e-053149226181633
Pubmed

CircEHMT1 inhibits metastatic potential of breast cancer cells by modulating miR-1233-3p/KLF4/MMP2 axis.

KLF4 MMP2

5.45e-053149232209259
Pubmed

Targeted disruption of S100P suppresses tumor cell growth by down-regulation of cyclin D1 and CDK2 in human hepatocellular carcinoma.

S100P CDK2

5.45e-053149219885547
Pubmed

Interaction between the dihydropyridine receptor Ca2+ channel beta-subunit and ryanodine receptor type 1 strengthens excitation-contraction coupling.

CACNA1S RYR1

5.45e-053149216357209
Pubmed

alpha-Neurexins are required for efficient transmitter release and synaptic homeostasis at the mouse neuromuscular junction.

NRXN3 NRXN2

5.45e-053149216406382
Pubmed

SIRT1 Functions as a Negative Regulator of Eukaryotic Poly(A)RNA Transport.

PABPC1 PABPC3

5.45e-053149228756945
Pubmed

The poly(A)-binding protein genes, EPAB, PABPC1, and PABPC3 are differentially expressed in infertile men with non-obstructive azoospermia.

PABPC1 PABPC3

5.45e-053149226843391
Pubmed

Triad proteins and intracellular Ca2+ transients during development of human skeletal muscle cells in aneural and innervated cultures.

CACNA1S RYR1

5.45e-053149211206130
GeneFamilyMitogen-activated protein kinase-activated protein kinases

RPS6KA5 RPS6KA2 RPS6KA3

2.18e-05119431156
GeneFamilyPhosphatidylinositol 3-kinase subunits

PIK3C2G PIK3C3

7.34e-048942831
GeneFamilyATPases Ca2+ transporting

ATP2B2 ATP2B4

9.40e-0499421209
GeneFamilyMyosin light chains|EF-hand domain containing

MYL2 MYL10

2.34e-0314942657
GeneFamilyX-linked mental retardation|Angiotensin receptors

ATRX RPS6KA3 DMD

2.64e-0353943103
GeneFamilyZinc fingers C2H2-type|ZF class homeoboxes and pseudogenes

ADNP2 ZEB2

2.69e-0315942529
GeneFamilyDNA helicases

ERCC3 INO80

3.46e-03179421167
GeneFamilyZinc fingers|Zinc fingers PARP-type|Poly(ADP-ribose) polymerases

PARP6 PARP9

3.46e-0317942684
GeneFamilyRNA binding motif containing

PTBP3 CELF5 PABPC1 PABPC3 PSPC1

5.09e-03213945725
GeneFamilyProtein tyrosine phosphatases, receptor type

PTPRD PTPRR

5.27e-0321942813
GeneFamilyEF-hand domain containing

MYL2 EFHB SELENON S100P MYL10

5.72e-03219945863
GeneFamilyPHD finger proteins|Lysine demethylases

KDM2A KDM4B

6.85e-0324942485
CoexpressionGAL_LEUKEMIC_STEM_CELL_UP

ALS2CL ITGB4 PDLIM5 PIK3C3 AGT SENP6 ZC3H7B

8.98e-061301477M17428
CoexpressionFULLER_PBMC_F_TULARENSIS_VACCINE_LVS_AGE_22_54YO_18HR_TO_336HR_SUSTAINED_UP

SPN ARRB1 LRP1

1.42e-0591473M41059
CoexpressionGSE360_T_GONDII_VS_B_MALAYI_LOW_DOSE_DC_UP

ATRX RGS1 ZNF518A RFTN1 TESK2 KDM2A IFI44L KDM4B

1.61e-051971478M5217
CoexpressionBUSSLINGER_DUODENAL_MATURE_ENTEROCYTES

CIDEB ABHD3 HKDC1 APOB KLF4 ITGB4 ATG4B AHNAK LRP1

1.64e-052591479M40029
CoexpressionIGARASHI_ATF4_TARGETS_DN

RPS6KA3 KLF4 S100P ARRB1 ASPH AP5M1

1.93e-05981476M4779
CoexpressionNAKAYA_PBMC_FLUARIX_FLUVIRIN_AGE_18_50YO_CORRELATED_WITH_HAI_28DY_RESPONSE_AT_7DY_POSITIVE

CIDEB SEC11C RRM2 EMSY NOMO1 NOMO2 NOMO3

3.73e-051621477M41204
CoexpressionGABRIELY_MIR21_TARGETS

PTBP3 ATRX RPS6KA3 DDX46 VPS13A PARP9 DMD MGA ATP2B4

3.88e-052891479M2196
ToppCelldroplet-Marrow-BM_(NON-STC)-30m-Myeloid-basophil|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DBI KLF4 DDX46 NT5DC2 AHNAK FAM210B LRP1 ALAS2 ATP2B4

8.86e-0917814891a578d16008a450c42e73a996247ffecdc2c43f0
ToppCellCOVID_vent-Lymphocytic-Plasma_cell-IgA_Plasmablast|COVID_vent / Disease condition, Lineage, Cell class and subclass

SRP54 SEC11C RRM2 NOMO1 NOMO2 NT5DC2 BUB1 DNAJC3 NOMO3

2.14e-08197148999fe44ef42c65d24fe64947fd5bf6d91b9a4b2c3
ToppCelldroplet-Heart-nan-3m|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RANBP2 ATRX RPS6KA3 SRP54 ZEB2 AHNAK MYOCD DMD

1.38e-071761488749b47eac5436fa34e0d243ffbc6f1897f4e431e
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-24m-Neuronal-neuron|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TRPC5 NRIP3 ARRB1 NRXN3 CADPS SLC6A5 ATP2B2 UNC80

2.29e-0718814881efbc99bcd6542e5d9fa91edb7c4295167914786
ToppCellMid-temporal_gyrus_(MTG)-Neuronal|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

CELF5 NRXN3 PTPRR CADPS RIMS1 ATP2B2 UNC80 CDH18

3.14e-071961488676c56b44ac29f7baecb62f49bb8597cc74c0a88
ToppCellControl-Control-Lymphocyte-T/NK-NK_activated|Control / Disease, condition lineage and cell class

DOC2A SPN NRXN2 AHNAK TNKS1BP1 PARP9 IFI44L ATP2B4

3.40e-07198148876d5fe4e5bbe6c73a6ca409b80b5c3924e07cab7
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

CELF5 NRXN3 PTPRR CADPS RIMS1 ATP2B2 UNC80 CDH18

3.40e-0719814880ff30edfd3c133a42e8cb96e1631a1143215f808
ToppCellNeuronal|World / cells hierarchy compared to all cells using T-Statistic

CELF5 NRXN3 PTPRR CADPS RIMS1 ATP2B2 UNC80 CDH18

3.67e-07200148848d801219bc771d6c7e151dc88ca4c179988de85
ToppCellCOVID-19-kidney-Technical/muscle_(Imm)|kidney / Disease (COVID-19 only), tissue and cell type

IKZF1 RYR1 NRXN3 PTPRR CADPS DMD CDH18

1.25e-06163148719c28ce16a588a7f4a035c32726f6ccd67702b5b
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Immune-Myeloid-Granulocytic-Mast_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

INTS6L HK2 RPS6KA5 LDHAL6B IKZF1 RGS1 CADPS

1.31e-0616414872c48c6e4eeee845f0563982d0bfa2a176ca5ef61
ToppCellMid-temporal_gyrus_(MTG)-Non-neuronal-Macroglial-Astro-Astrocyte-Astro_L1_FGFR3_FOS|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

PIRT DBI ITGB4 SERPINI2 AHNAK AGT IFI44L

2.17e-061771487191c14e0ef162536028b841f3759aaddef59b49d
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Immune-Myeloid-Granulocytic|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

INTS6L HK2 LDHAL6B IKZF1 RGS1 S100P CADPS

2.25e-061781487af9bcee71fb44a6342d4b92bba5b8ddfeeaa24b2
ToppCellLPS-antiTNF-Epithelial_alveolar-AT_2|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SFTA2 AP1M2 SEC11C GRHL2 S100P NRXN3 CDH18

2.43e-061801487b798a3fa2dd15b68aa4267f665559527043dcc07
ToppCellMid-temporal_gyrus_(MTG)-Non-neuronal-Macroglial-Astro-Astrocyte-Astro_L1_FGFR3_MT1G|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

HKDC1 DBI ITGB4 PDLIM5 SERPINI2 AHNAK AGT

3.01e-06186148741e03be964044dae690d566bd078dab3d8045eba
ToppCellEntopeduncular-Neuronal|Entopeduncular / BrainAtlas - Mouse McCarroll V32

CELF5 TRPC5 NRIP3 NRXN3 CADPS ATP2B2 UNC80

3.72e-0619214874c35e5c28a40b439044797ba1f06cb7c36b2a8de
ToppCellsevere-Plasmablast|severe / disease stage, cell group and cell class

SRP54 SEC11C RRM2 NOMO1 NT5DC2 BUB1 DNAJC3

4.12e-061951487e11616ad568e50e4c720b50b0c071f484c31d16b
ToppCellSomatosensory_Cortex_(S1)-Neuronal|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

NRXN3 PTPRR CADPS RIMS1 ATP2B2 UNC80 CDH18

4.55e-061981487c01091ef18e096d792ea2a7a715764a5b215355f
ToppCellprimary_auditory_cortex_(A1C)-Neuronal|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

NRXN3 PTPRR CADPS RIMS1 ATP2B2 UNC80 CDH18

4.55e-0619814876d18b45eda4014759e6dd282d78ffd28df8a6044
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

NRXN3 PTPRR CADPS RIMS1 ATP2B2 UNC80 CDH18

4.55e-0619814874ca5ff320905ab4ff60ed90a5522227c782142a6
ToppCellFetal_brain-fetalBrain_Zhong_nature-GW23-Neuronal-GABAergic_neurons|GW23 / Sample Type, Dataset, Time_group, and Cell type.

RPS6KA2 NRIP3 ZEB2 NRXN3 NRXN2 PTPRR CADPS

4.86e-062001487c6bbd33bca86ac7a76a7ba704b3e141237d04549
ToppCellControl-Plasmablast|World / disease group and sub_cluster of B and Plasma cells(res = 0.5)

SPN SEC11C NOMO1 NOMO2 NT5DC2 AHNAK

9.13e-061451486fe68582f5a15b9714cb84fa32ac880e13cb69895
ToppCellRV-16._Neuronal|World / Chamber and Cluster_Paper

MYL2 ITGB4 FAM135B NRXN3 AHNAK AGT

1.07e-0514914863a2f8c4173dcf9e3f8d3b8ffddbc597098adf7a9
ToppCellfacs-Liver-Hepatocytes|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TCN1 ACO1 ABHD3 ABCB4 PTPRD AGT

1.39e-051561486e2cda3ad4e5f44a80133864c5a38b766afb952ce
ToppCellFetal_29-31_weeks-Epithelial-lung_neuroendocrine_cell_(PNEC)-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

SEC11C CADPS TRPV3 RIMS1 UNC80 CDH18

1.54e-0515914867747cef94c55144fddcd024a7495318357f1351b
ToppCellCOVID-19-kidney-Technical/muscle_(Mes)|kidney / Disease (COVID-19 only), tissue and cell type

RYR1 NRXN3 CADPS RIMS1 DMD CDH18

1.54e-0515914865335cbcdeaf2bbd0268bbfe0e45c8c0d288e640d
ToppCelldroplet-Heart-HEART_(LV+RV_ONLY)-30m-Hematologic-nan|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SPN PABPC1 RYR1 FAM210B ALAS2

1.73e-059614857a1a27d996c2bbcd922da524969f568f0575dfad
ToppCellPND10-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_ILC-NK-ILC-ILC_prolif|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

RPS6KA5 SPN SEC11C RRM2 RGS1 ANKAR

2.18e-05169148620fbf78382fb0ba9a63ab1aa0abc615476994ac5
ToppCellTCGA-Liver-Primary_Tumor-Hepatocellular_Carcinoma-Hepatocellular_Carcinoma-4|TCGA-Liver / Sample_Type by Project: Shred V9

COX19 ABHD3 SLC6A11 ATG4B HECTD2 NT5DC2

2.18e-0516914860a3ba6b5d6cff9d3d7f56046063cfc3a37ae1156
ToppCellPND14-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_ILC-NK-ILC-ILC_G2M|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

RPS6KA5 SPN RRM2 PABPC1 RGS1 BUB1

2.25e-051701486b04e2f84024baaae9b4ff19bdac8c69afdb92a76
ToppCellprimary_auditory_cortex_(A1C)-Non-neuronal-Macroglial-Astro-Astrocyte-Astro_L1_FGFR3_FOS|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

HK2 PIRT ITGB4 SERPINI2 AHNAK AGT

2.57e-05174148653c2c132566a7682f3268c7f9138700f09c3b94d
ToppCellCOVID-19-lung-MAST|COVID-19 / Disease (COVID-19 only), tissue and cell type

INTS6L RPS6KA5 IKZF1 RGS1 ZEB2 CADPS

2.74e-051761486473c45a381ca109207d66ed1635668b391ea0e1f
ToppCelldroplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_A_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ATRX KLF4 PTPRD PIK3C2G AGT DMD

2.83e-051771486426a9845df7fd13b02e744532c336c60bc4d4a22
ToppCelldroplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_A_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KLF4 NRXN3 PTPRD PIK3C2G AGT DMD

2.83e-0517714861dc69c661e70e7e22bd9d7cf953eb638da9fd43c
ToppCellfacs-Lung-18m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell-pulmonary_artery_endothelial_cell_l27|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ENPP6 ITGB4 ABCB4 PTPRR ATP2B2 ATP2B4

2.83e-051771486d68132e145bd413404fdbe215b5dbe520e756e50
ToppCelldroplet-Spleen-nan-24m-Hematologic-nan|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RRM2 ABCB4 NT5DC2 FAM210B ALAS2 ATP2B4

3.01e-051791486f3f9c7e575bc4d9d3bce649b90254182e8f6aaec
ToppCelldroplet-Lung-3m-Epithelial-alveolar_epithelial-type_I_pneumocyte-type_1_alveolar_epithelial_cell|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SFTA2 CIDEB CACNA1S TCN1 GRHL2 PIK3C2G

3.01e-051791486ca70a5518c5a5392e088c103e0cb44aa084f5332
ToppCelldroplet-Lung-3m-Epithelial-alveolar_epithelial-type_I_pneumocyte|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SFTA2 CIDEB CACNA1S TCN1 GRHL2 PIK3C2G

3.01e-051791486c451b074b04eb5d6c575c6abaedda579c6744bbf
ToppCelldroplet-Spleen-nan-24m-Hematologic|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RRM2 ABCB4 NT5DC2 FAM210B ALAS2 ATP2B4

3.01e-05179148601e0b49e7f03ac9c3e6c34708ead300d27236b8b
ToppCell3'-Distal_airway-Immune_Lymphocytic-Lymphocytic_T/NK-CD4-positive,_alpha-beta_T_cell-CD4_T_cells-CD4_T_cells_L.1.1.1.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

INTS6L SCLY RFTN1 HECTD2 VPS13A SENP6

3.01e-0517914866bbb32d7e582a96cb3cfc3eb911b05d518e7d5e9
ToppCellLPS-antiTNF-Epithelial_alveolar-AT_2-AT2_Progenitor|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SFTA2 SEC11C DBI GRHL2 S100P NRXN3

3.01e-0517914867db6b97a1c4c7a163d5da4351ba36ac1785d9d7b
ToppCellfacs-Brain_Non-Myeloid-Hippocampus_-18m-Macroglial|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PIRT SEC11C DBI SIRT2 NRXN2 MMP2

3.20e-0518114861037051eb82313c13346617b33f3c4c648181c4d
ToppCelldroplet-Marrow-nan-3m-Hematologic-nan|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ATRX SRP54 RGS1 JAK1 VPS13A SENP6

3.30e-051821486e78ba2c5cae480c16a596ce7c3bf2d480becacf4
ToppCelldroplet-Marrow-nan-3m-Hematologic|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ATRX SRP54 RGS1 JAK1 VPS13A SENP6

3.30e-0518214861710eab3037a87609d21838be2d2d29c3bc36651
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

APOB PTPRD PIK3C2G MYOCD DMD UNC80

3.51e-0518414862cbed6462fea2622871bb7e49b0df3d984239281
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-24m-Epithelial-nan|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ANKK1 FBXW10 EFHB CFAP54 TESK2 AGT

3.51e-0518414866b0c110d8930df99043c3b99cf4d873985126960
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-24m-Epithelial|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ANKK1 FBXW10 EFHB CFAP54 TESK2 AGT

3.51e-05184148635928fc5f7bbf8c7b09181a2bd27e22dff42ec16
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

APOB PTPRD PIK3C2G MYOCD DMD UNC80

3.51e-0518414862b19a8c5f823e00812908b23e66bb4e563278aff
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

APOB PTPRD PIK3C2G MYOCD DMD UNC80

3.51e-051841486ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal-Glutamatergic_Excit|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

PTPRD PTPRR VPS13A ATP2B4 RASAL1 CDH18

3.73e-05186148684ba666237c18189d7e7556bd92dd953af733c00
ToppCelldroplet-Lung-21m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell-pulmonary_artery_endothelial_cell_l27|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ENPP6 ITGB4 PTPRR TNKS1BP1 ATP2B2 ATP2B4

3.73e-051861486c116cc9f41971622264434ebe29d18e719b0ae19
ToppCelldroplet-Spleen-SPLEEN-30m-Hematologic-nan|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RRM2 ABCB4 NT5DC2 BUB1 ALAS2 ATP2B4

3.73e-0518614867cdcf507a9a1349ed2cf62b79116367c3fc732dd
ToppCelldroplet-Spleen-SPLEEN-30m-Hematologic|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RRM2 ABCB4 NT5DC2 BUB1 ALAS2 ATP2B4

3.73e-051861486ac6e32cf07f0f013101ca7aedae0c562857f182b
ToppCellAnterior_Cingulate_gyrus_(CgG)-Non-neuronal-Macroglial-Astro-Astrocyte-Astro_L1_FGFR3_MT1G|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

HKDC1 ITGB4 SERPINI2 AHNAK AGT IFI44L

3.84e-0518714862b1b2c3792d6c9ab69675ce88842bb589414b530
ToppCellLPS-IL1RA-Epithelial_alveolar|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SFTA2 AP1M2 SEC11C GRHL2 S100P NRXN3

3.96e-0518814866164d467b612767ceba15de34176bcc8e8c36ab8
ToppCellEndothelial-Endothelial-E|Endothelial / shred on cell class and cell subclass (v4)

ENPP6 ITGB4 NRXN3 PTPRR MMP2 ATP2B4

3.96e-0518814862777eb7689b271c199021fe7d9db88ccebff14de
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-24m-Neuronal-nan|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NRIP3 NRXN3 NRXN2 RIMS1 UNC80 CDH18

4.08e-051891486f57200c93d39c9bce1adba0a6a1c178c028dd86b
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PDLIM5 RFTN1 CADPS MYOCD DMD ATP2B4

4.20e-0519014862e88e366d377d74deb53a4ea870973ce5c6532e8
ToppCell3'-Broncho-tracheal-Epithelial-Neuro-endocrine/ionocytic-lung_neuroendocrine_cell-Neuroendocrine|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SEC11C CADPS AGT SLC6A5 UNC80 CDH18

4.20e-05190148640d8b3403f4e38436b961cd3a2e69826cbae3042
ToppCell3'-Broncho-tracheal-Epithelial-Neuro-endocrine/ionocytic-lung_neuroendocrine_cell|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SEC11C CADPS AGT SLC6A5 UNC80 CDH18

4.20e-051901486a9a705455019e28d655636de73b07540798f82e6
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PDLIM5 RFTN1 CADPS MYOCD DMD ATP2B4

4.20e-0519014860028f886c789ba238c031eae5d96acaed4af8c25
ToppCelldroplet-Heart-nan-3m-Mesenchymal|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SRP54 ZEB2 ASPH LRP1 MYOCD MMP2

4.20e-05190148696a92212ea3fb35fa3d0da495e504edc61c71c23
ToppCell3'-Broncho-tracheal-Epithelial-Neuro-endocrine/ionocytic-lung_neuroendocrine_cell-Neuroendocrine-Neuroendocrine_L.0.7.2.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SEC11C CADPS AGT SLC6A5 UNC80 CDH18

4.20e-051901486f6cbf6d292f488ada5f7581e1dceba6198b933d1
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

DCHS2 ZEB2 PDLIM5 RFTN1 LRP1 DMD

4.32e-051911486a6c57627077fa980b7ec1d3894b5f31bfb11b738
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Lymphoid-CD4/CD8-Prolif_T-G|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

PTBP3 SPN RPS6KA3 IKZF1 RRM2 BUB1

4.32e-051911486912e2d10d3423aa7f708fcf2b11da1845f12d7d3
ToppCellControl-Plasmablast|Control / disease group and sub_cluster of B and Plasma cells(res = 0.5)

SPN SEC11C NOMO1 NOMO2 NT5DC2 DNAJC3

4.32e-0519114863df5bbdb29bbcbcb8476fdf126b6d4c1ac67d64b
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Lymphoid-CD4/CD8-Prolif_T|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

PTBP3 SPN RPS6KA3 IKZF1 RRM2 BUB1

4.32e-05191148677a2746b6d9c53b08d4405411c16fcc5a6c734ce
ToppCellPBMC_fresh-frozen-Mild-Moderate_progression_d12-25|PBMC_fresh-frozen / Compartment, severity and other cell annotations on 10x 3' data (130k)

RANBP2 WBP11 RGS1 KDM2A ALAS2 IFI44L

4.32e-0519114861ecd9849d14d5ebf3daf610e83fb50820cafd3ed
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

DCHS2 ZEB2 PDLIM5 RFTN1 LRP1 DMD

4.32e-0519114868f6d592edc32fdb901af30501d4360512334e8c2
ToppCellCOVID-19_Severe-Lymphoid_P|COVID-19_Severe / Disease group, lineage and cell class

SRP54 SEC11C RRM2 NOMO1 NT5DC2 BUB1

4.45e-0519214863d0240491296757b3125f6e861bbaca06bbc5068
ToppCellCOVID-19_Severe-Lymphoid_P-Plasmablast|COVID-19_Severe / Disease group, lineage and cell class

SRP54 SEC11C RRM2 NOMO1 NT5DC2 BUB1

4.45e-05192148690af8dad4e6f80b5ecd62027deeb2e4cea6b24bb
ToppCellPBMC-Severe-Lymphocyte-B-Plasmablast|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)

SRP54 SEC11C RRM2 NOMO1 NT5DC2 BUB1

4.58e-051931486227d82059a9f99937e0188ff57f2d0e485ebfe69
ToppCellfacs-Brain_Non-Myeloid-Cortex-24m-Neuronal-neuron|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CELF5 NRXN3 NRXN2 ATP2B2 ATP2B4 UNC80

4.58e-0519314868689a70a33a7c3823dc647d41ac0160e7c3ae396
ToppCellPBMC-Severe-Lymphocyte-B-Plasmablast|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

SRP54 SEC11C RRM2 NOMO1 NT5DC2 BUB1

4.58e-051931486ce3873ece35fd2155ea235cb3c8bcd235cc0ebde
ToppCellPBMC-Severe-Lymphocyte-B-Plasmablast-Plasmablast|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

SRP54 SEC11C RRM2 NOMO1 NT5DC2 BUB1

4.58e-0519314868f57b0473a2c2c07f83e5fe70f16862b1bb3b514
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-24m-Neuronal|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NRIP3 NRXN3 NRXN2 RIMS1 UNC80 CDH18

4.58e-0519314865fb7808dd971c1cc64c2bd4f8f1de646fb2d77f4
ToppCellfacs-Brain_Non-Myeloid-Cortex-24m-Neuronal|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CELF5 NRXN3 NRXN2 ATP2B2 ATP2B4 UNC80

4.58e-051931486be28070c049e7cb68bcd54f582226eb2f5e4bc1c
ToppCellPBMC-Severe-Lymphocyte-B-Plasmablast-Plasmablast-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

SRP54 SEC11C RRM2 NOMO1 NT5DC2 BUB1

4.58e-05193148638bb14df7f05c29565a1c7f175fafe636e543bf8
ToppCellPBMC-Severe-Lymphocyte-B-Plasmablast-Plasmablast|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)

SRP54 SEC11C RRM2 NOMO1 NT5DC2 BUB1

4.58e-0519314863ba6d44248690b80f4caf791d463e60f1ab816c4
ToppCellfacs-Brain_Non-Myeloid-Cortex-24m-Neuronal-nan|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CELF5 NRXN3 NRXN2 ATP2B2 ATP2B4 UNC80

4.58e-0519314860c652ebe22ce5d2927599dd97ef1920547858395
ToppCelldroplet-Marrow-BM_(NON-STC)-30m-Myeloid-promonocyte|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DBI KLF4 ZEB2 AHNAK LRP1 MFSD1

4.58e-0519314865a201ee6f132357c9aacfbad3ae56ed9854c25fd
ToppCell10x_3'_v2v3-Non-neoplastic-Myeloid-DC-cDC2-F|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

RPS6KA3 KLF4 PABPC1 RGS1 PRX IFI44L

4.85e-051951486cb27f6ca8b02438c353c9dff2f76d2656bb5b29a
ToppCelldroplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ATRX RPS6KA2 CADPS VPS13A MGA UNC80

4.85e-0519514867796ea9247f4c63762f0de8490fed08b9717fa23
ToppCellSecretory|World / shred by cell class for bronchial biopsy

HK2 TCN1 RPS6KA3 SEC11C S100P RIMS1

4.85e-05195148652f8281fe0df67cec3faa780a23ed6343ed5a6ba
ToppCellcontrol-Lymphoid-Treg|Lymphoid / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

SPN SLC35G2 RGS1 ANKAR IFI44L ATP2B4

4.85e-05195148666959ae839eb60a573da06bdd227090ebb5bb9ed
ToppCellCOVID-19-T_cells-Cycling_NK/T_cells|COVID-19 / group, cell type (main and fine annotations)

KNTC1 SPN IKZF1 RRM2 BUB1 ALAS2

4.85e-051951486764ed100c28d9bc93ee5ecabc5291c8f184d78da
ToppCellmetastatic_Brain-Myeloid_cells-Microglia/Mac|metastatic_Brain / Location, Cell class and cell subclass

DBI KLF4 RGS1 ZEB2 LRP1 MFSD1

4.85e-051951486ae48d493ebda5f87781181a3d1d73d8f84fc5e77
ToppCelldroplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ATRX RPS6KA2 CADPS VPS13A MGA UNC80

4.85e-0519514863e519cffa6144a62b06124642a14c9ff39b76554
ToppCelldroplet-Limb_Muscle-MUSCLE-30m-Mesenchymal|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HK2 ATRX SRP54 PTPRD LRP1 MMP2

4.85e-0519514865c86fddd6d0530beecf45ea5ba6b823123847696
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ZEB2 PDLIM5 RFTN1 CADPS MYOCD DMD

4.99e-0519614861522958a92e0126326a9f0d9fb1c5b5c50b001ea
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ZEB2 PDLIM5 RFTN1 CADPS MYOCD DMD

4.99e-0519614861c8294014713684b50885e638668f2ce75f357f0
ToppCellMild/Remission-Plasmablast|Mild/Remission / disease group and sub_cluster of B and Plasma cells(res = 0.5)

SPN SRP54 SEC11C NOMO1 NT5DC2 DNAJC3

4.99e-051961486dcf0a804a79a05454658498d1f87320c7e079219
ToppCell10x_3'_v3-blood_(10x_3'_v3)-myeloid-myeloid_monocytic-classical_monocyte|blood_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

KLF4 PABPC1 ZEB2 AHNAK LRP1 MFSD1

4.99e-05196148628e9e191361966df3a9bd48450090577aa72a999
ToppCellBronchial-NucSeq-Epithelial-Epi_airway_neuro-secretory-Neuroendocrine|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

RRM2 NRIP3 FAM135B CADPS ASTN1 UNC80

4.99e-0519614864bdc304c0c9d8bebe1a6a8a27e44acd1e8113725
ToppCell11.5-Distal-Epithelial|Distal / Age, Tissue, Lineage and Cell class

SFTA2 AP1M2 SEC11C GRHL2 PIK3C2G DMD

5.14e-051971486ae9505ae7e6c5e8c280f9bfb1ba79ab5bd8895e3
ToppCellSevere|World / disease group and sub_cluster of B and Plasma cells(res = 0.5)

SEC11C RRM2 NOMO1 NT5DC2 BUB1 DNAJC3

5.14e-051971486df3f58b58f82c42c65b0a09c054b669b34502037
ToppCellParenchymal-10x3prime_v2-Epithelial-Epi_airway_ciliated-Deuterosomal|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

DOC2A FBXW10 RRM2 ZNF610 SERPINI2 BUB1

5.14e-051971486861e8df9bd74dc5e17bafdc1fb3fef546753c73a
ToppCellmLN-(2)_B_cell-(20)_B_cell_IgA_Plasma|mLN / shred on region, Cell_type, and subtype

KNTC1 TCN1 SEC11C NT5DC2 DNAJC3 CDH18

5.14e-051971486a39b384ee9824a08c3b544a9c3c7f0f95f08d6a7
ToppCellTCGA-Pancreas-Primary_Tumor-Pancreatic_Adenocarcinoma-Ductal_Adenocarcinoma|TCGA-Pancreas / Sample_Type by Project: Shred V9

SFTA2 TCN1 HKDC1 GRHL2 ITGB4 S100P

5.14e-051971486d8355f07a53e771052f9ab6b38814365dfe8d9ae
ToppCellmLN-B_cell-B_cell_IgA_Plasma|mLN / Region, Cell class and subclass

KNTC1 TCN1 SEC11C NT5DC2 DNAJC3 CDH18

5.14e-05197148620822fce311326765b71337ce501ba44ea14f58f
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW19-Neuronal-Interneuron|GW19 / Sample Type, Dataset, Time_group, and Cell type.

IKZF1 RYR1 NRXN3 PTPRR UNC80

5.26e-051211485b2d571f571133c281d72584fe925cebbd2317829
Drugfluo-3

CACNA1S RYR1 PTPRD AGT SLC6A5 RIMS1 ATP2B2 ATP2B4

1.23e-061221468CID000104978
DrugGramine [87-52-5]; Up 200; 23uM; MCF7; HT_HG-U133A

RPS6KA2 TRPC5 ALS2CL BUB1 ASPH MMP2 ZC3H7B MYL10 BAHCC1

4.28e-0619214692799_UP
DrugSTOCK1N-35215; Down 200; 10uM; PC3; HT_HG-U133A

SPN TRPC5 ITGB4 RYR1 BUB1 ASPH RIMS1 ZC3H7B CDK2

4.65e-0619414696380_DN
DrugLoracarbef [121961-22-6]; Down 200; 10.8uM; HL60; HT_HG-U133A

STRN3 ATRX ALS2CL PDLIM5 ABCB4 ASPH MYL10 EDRF1 KDM4B

5.27e-0619714692970_DN
DrugBethanechol chloride [590-63-6]; Down 200; 20.4uM; HL60; HT_HG-U133A

MON2 STRN3 ATRX SPN RPS6KA2 KLF4 ABCB4 ASPH KDM4B

5.27e-0619714692975_DN
DrugOxalamine citrate salt [1949-20-8]; Down 200; 9.2uM; PC3; HT_HG-U133A

CIDEB RPS6KA2 TRPC5 SCLY PDLIM5 PTPRR LRP1 ZC3H7B KDM4B

5.72e-0619914696624_DN
DrugNSC618487

MYL2 RPS6KA5 SPN RPS6KA2 RPS6KA3 APOB JAK1 SIRT2 PIK3C2G PIK3C3 AIFM1 AGT SLC6A5 PARP9 MMP2 MYL10 ATP2B2 ATP2B4 CDK2

8.54e-0693314619CID000005279
DrugKB-R7943

CACNA1S MYL2 TRPC5 RYR1 ATP2B2

1.25e-05471465CID004534086
Drugnifedipine

CACNA1S MYL2 ACO1 TRPC5 LDHAL6B DBI RYR1 AGT MMP2 MYL10 ATP2B2 ATP2B4

1.57e-0541514612CID000004485
Druglanthanum

CACNA1S TRPC5 RYR1 AIFM1 RIMS1 ATP2B2 ATP2B4

2.83e-051361467CID000023926
DrugAmethopterin (R,S) [59-05-2]; Down 200; 8.8uM; MCF7; HT_HG-U133A

DOC2A CIDEB PTBP3 SPN FAM210B BUB1 KDM4B BAHCC1

3.09e-0518914683214_DN
DrugAlprenolol hydrochloride [13707-88-5]; Down 200; 14uM; MCF7; HT_HG-U133A

ATRX ALS2CL EMSY FAM210B BUB1 ASPH ZC3H7B RASAL1

3.45e-0519214683188_DN
DrugSelegiline hydrochloride [14611-52-0]; Down 200; 17.8uM; MCF7; HT_HG-U133A

PTBP3 RPS6KA2 ALS2CL ZNF3 ARRB1 ASPH ZC3H7B BAHCC1

3.58e-0519314684146_DN
Drug2-propylpentanoic acid; Down 200; 1000uM; MCF7; HT_HG-U133A

RPS6KA5 RPS6KA2 ITGB4 EMSY MYL10 EDRF1 RASAL1 BAHCC1

4.00e-0519614685569_DN
DrugBenzydamine hydrochloride [132-69-4]; Up 200; 11.6uM; MCF7; HT_HG-U133A

CIDEB PTBP3 ATRX RPS6KA5 RPS6KA2 TAF1C VPS13A ATP2B4

4.14e-0519714687169_UP
DrugMonobenzone [103-16-2]; Up 200; 20uM; MCF7; HT_HG-U133A

CIDEB TAF1C ASPH SENP6 MYL10 ATP2B4 RASAL1 KDM4B

4.14e-0519714685312_UP
DrugAdrenosterone [382-45-6]; Up 200; 13.4uM; PC3; HT_HG-U133A

CIDEB SCLY ITGB4 RYR1 SERPINI2 DMD KDM4B BAHCC1

4.14e-0519714685045_UP
DrugSulfamonomethoxine [1220-83-3]; Down 200; 14.2uM; MCF7; HT_HG-U133A

PTBP3 STRN3 SPN IKZF1 ITGB4 ZC3H7B EDRF1 RASAL1

4.14e-0519714683484_DN
DrugMefexamide hydrochloride [3413-64-7]; Down 200; 12.6uM; HL60; HG-U133A

RPS6KA5 SPN RGS1 ZEB2 ZNF3 VPS13A MYL10 DNAJC3

4.30e-0519814681438_DN
DrugPhenelzine sulfate [156-51-4]; Down 200; 17uM; HL60; HT_HG-U133A

PTBP3 SPN ITGB4 RGS1 PDLIM5 VPS13A KDM2A IFT122

4.45e-0519914682357_DN
DrugMethiazole; Up 200; 15uM; MCF7; HT_HG-U133A

RPS6KA2 ABHD3 PDLIM5 PRX AHNAK ASPH KDM4B CDH18

4.45e-0519914683878_UP
DrugTetracaone hydrochloride [136-47-0]; Up 200; 13.2uM; HL60; HG-U133A

PTBP3 RANBP2 TCN1 SERPINI2 ASPH MYL10 DNAJC3 KDM4B

4.45e-0519914681739_UP
DrugSerotonin hydrochloride [153-98-0]; Up 200; 18.8uM; HL60; HT_HG-U133A

PTBP3 IKZF1 SCLY ARRB1 FAM210B BUB1 ASPH ZC3H7B

4.45e-0519914682449_UP
DrugPiperine [94-62-2]; Up 200; 14uM; PC3; HT_HG-U133A

PTBP3 NRIP3 PDLIM5 NRXN3 PTPRR AHNAK FAM210B ATP2B4

4.45e-0519914684247_UP
DrugRilmenidine hemifumarate [54187-04-1]; Up 200; 8.4uM; MCF7; HT_HG-U133A

CIDEB STRN3 RPS6KA2 ALS2CL PRX AGT ZC3H7B EDRF1

4.61e-0520014685532_UP
DrugAC1L1IHP

STRN3 MYL2 RPS6KA5 ACO1 RPS6KA2 RPS6KA3 APOB PTPRD PIK3C2G PIK3C3 AGT CEP131 MYL10 RASAL1 CDK2

7.10e-0572814615CID000004584
Drugcalmidazolium chloride

MYL2 TCN1 TRPC5 AGT MYL10 ATP2B2 ATP2B4

7.95e-051601467CID000002531
Drugisoflurane

CACNA1S RPS6KA3 LDHAL6B RYR1 AGT ALAS2 DMD ATP2B2 ATP2B4

8.19e-052791469CID000003763
Drugcaged ATP

MYL2 CHD1L MYL10 ATP2B2 ATP2B4

8.76e-05701465CID000123806
DrugOvta

RPS6KA5 RPS6KA2 RPS6KA3

8.93e-05141463CID003081047
DrugAD 288

RPS6KA5 RPS6KA2 RPS6KA3

8.93e-05141463CID000073553
Drugmag-fura-2

CACNA1S RYR1 ATP2B2 ATP2B4

9.09e-05371464CID000123839
DrugNSC-683864

ERCC3 RPS6KA5 RPS6KA2 RPS6KA3 PIK3C2G PIK3C3 CDK2

1.04e-041671467CID000148191
DrugTetracycline

CIDEB COX19 AMACR RPS6KA2 APOB DBI RRM2 ABCB4 JAK1 ATG4B PIK3C2G AGT MMP2 MYL10

1.05e-0466814614ctd:D013752
Drugorthovanadate

ENPP6 RYR1 ABCB4 JAK1 PTPRD PIK3C2G PIK3C3 AIFM1 SLC2A12 ATP2B2 ATP2B4

1.19e-0443514611CID000061672
Drugglufosinate

ACO1 PDLIM5 RYR1 SERPINI2 LRP1

1.30e-04761465CID000004794
DrugR165481

RPS6KA5 RPS6KA2 RPS6KA3

1.36e-04161463CID005459348
Drugcarbachol

CACNA1S MYL2 RPS6KA5 RPS6KA2 RPS6KA3 TRPC5 RYR1 PIK3C2G PIK3C3 AGT MMP2 MYL10 ATP2B2 ATP2B4

1.42e-0468814614CID000002551
Drughemicholinium-3

RANBP2 SLC6A11 AGT VPS13A SLC6A5

1.47e-04781465CID000003585
Druglinopirdine

RPS6KA2 RPS6KA3 ATP2B2 ATP2B4

1.65e-04431464CID000003932
DrugSuccimer

STRN3 ATRX RPS6KA5 RPS6KA2 TRPC5 IKZF1 KLF4 ZEB2 PDLIM5 ZNF518A DDX46 NRXN3 CADPS AHNAK AGT ASPH LRP1 IFI44L MGA DNAJC3

1.70e-04126414620ctd:D004113
DrugSirolimus

RPS6KA2 RPS6KA3 PABPC1 RYR1 SIRT2 ATG4B AIFM1 AGT BUB1 MMP2 CDK2

1.79e-0445614611ctd:D020123
DrugPizotifen malate [5189-11-7]; Up 200; 9.4uM; PC3; HT_HG-U133A

RYR1 ZNF3 PTPRR BUB1 ASTN1 DNAJC3 KDM4B

1.96e-0418514675072_UP
DrugLasalocid sodium salt [25999-20-6]; Up 200; 6.6uM; PC3; HT_HG-U133A

KLF4 PARP6 NRXN3 PTPRD FAM210B LRP1 DNAJC3

1.96e-0418514676639_UP
Drugmercury

CIDEB CACNA1S LDHAL6B ZKSCAN7 RYR1 PIK3C2G PIK3C3 AGT BUB1 SENP6 ATP2B2 ATP2B4

2.01e-0454214612CID000023931
DrugProchlorperazine dimaleate [84-02-6]; Down 200; 6.6uM; MCF7; HT_HG-U133A

STRN3 ITGB4 PDLIM5 RFTN1 BUB1 ASPH CDK2

2.02e-0418614675010_DN
DrugXeC compound

CACNA1S TRPC5 RYR1 ATP2B2 ATP2B4

2.08e-04841465CID000005701
DrugNifuroxazide [965-52-6]; Down 200; 14.6uM; MCF7; HT_HG-U133A

ATRX SPN RPS6KA2 PDLIM5 ARRB1 VPS13A CDK2

2.16e-0418814674835_DN
Drugwortmannin; Up 200; 0.01uM; MCF7; HT_HG-U133A_EA

ATRX RPS6KA5 TAF1C PDLIM5 ARRB1 BUB1 ASPH

2.23e-041891467911_UP
DrugClioquinol [130-26-7]; Up 200; 13uM; PC3; HT_HG-U133A

PTBP3 TAF1C HKDC1 KLF4 IFI44L MYL10 RASAL1

2.31e-0419014674663_UP
DrugGSK-3beta Inhibitor VIII; Up 200; 10uM; PC3; HT_HG-U133A

SCLY KLF4 ASPH SENP6 CEP131 MGA EDRF1

2.31e-0419014677070_UP
Drug5707885; Down 200; 50uM; PC3; HT_HG-U133A

MON2 ZNF3 ARRB1 PTPRD BUB1 IFI44L CDK2

2.38e-0419114676390_DN
DrugTerfenadine [50679-08-8]; Down 200; 8.4uM; MCF7; HT_HG-U133A

STRN3 EMSY ZNF3 FAM210B VPS13A ATP2B4 EDRF1

2.38e-0419114672227_DN
DrugRapamycin; Down 200; 0.1uM; MCF7; HT_HG-U133A

STRN3 ATRX SCLY FAM210B ASPH EDRF1 BAHCC1

2.38e-0419114675204_DN
DrugRapamycin; Up 200; 0.1uM; MCF7; HT_HG-U133A

CIDEB DCHS2 TCN1 RPS6KA5 RYR1 ZNF3 NRXN3

2.46e-0419214675567_UP
Drugeverolimus

ERCC3 RPS6KA5 RPS6KA2 RPS6KA3 PIK3C2G PIK3C3

2.49e-041361466CID006442177
DrugFenoprofen calcium salt dihydrate [53746-45-5]; Down 200; 7.2uM; MCF7; HT_HG-U133A

PTBP3 ADNP2 KLF4 VPS13A IFT122 ZC3H7B DNAJC3

2.54e-0419314673412_DN
DrugICI182,780; Up 200; 1uM; MCF7; HT_HG-U133A

SPN IKZF1 ITGB4 PRX NRXN3 VPS13A RASAL1

2.54e-0419314677490_UP
DrugHydrastinine hydrochloride [4884-68-8]; Up 200; 16.4uM; MCF7; HT_HG-U133A

APOB SLC35G2 RYR1 BUB1 ASPH MYL10 KDM4B

2.54e-0419314672283_UP
Drugdihydropyridine

CACNA1S MYL2 RYR1 AGT DMD ATP2B2 ATP2B4

2.54e-041931467CID000104822
Drugcreatine

HK2 LDHAL6B RYR1 SLC6A11 SLC6A5 IFT122 DMD

2.54e-041931467CID000000586
Drugaspirin, USP; Down 200; 100uM; MCF7; HT_HG-U133A

PTBP3 CHD1L PDLIM5 RFTN1 BUB1 CEP131 CDK2

2.54e-0419314676964_DN
DrugProstaglandin E1; Down 200; 10uM; PC3; HT_HG-U133A

ATRX RPS6KA2 KLF4 PDLIM5 BUB1 ASPH BAHCC1

2.62e-0419414676555_DN
DrugTenoxicam [59804-37-4]; Up 200; 11.8uM; MCF7; HT_HG-U133A

PTBP3 DCHS2 SPN SLC35G2 NRIP3 DMD MYL10

2.62e-0419414674182_UP
DrugGuaifenesin [93-14-1]; Up 200; 20.2uM; MCF7; HT_HG-U133A

SPN RPS6KA2 IKZF1 EMSY ATP2B4 KDM4B CDH18

2.62e-0419414674371_UP
DrugFludrocortisone acetate [514-36-3]; Up 200; 9.4uM; PC3; HT_HG-U133A

MON2 DCHS2 SCLY KLF4 ZNF3 PARP6 RIMS1

2.62e-0419414673785_UP
DrugCarteolol hydrochloride [51781-21-6]; Down 200; 12.2uM; MCF7; HT_HG-U133A

TRPC5 CHD1L ITGB4 ZNF3 ARRB1 ASPH CDK2

2.62e-0419414674176_DN
DrugAmpyrone [83-07-8]; Down 200; 19.6uM; MCF7; HT_HG-U133A

CIDEB RPS6KA5 SPN ALS2CL VPS13A SENP6 ATP2B4

2.70e-0419514676845_DN
DrugDisopyramide [3737-09-5]; Down 200; 11.8uM; MCF7; HT_HG-U133A

PTBP3 ATRX RPS6KA5 CHD1L PDLIM5 BUB1 CDK2

2.70e-0419514677035_DN
DrugSuxibuzone [27470-51-5]; Up 200; 9.2uM; MCF7; HT_HG-U133A

MON2 RPS6KA2 IKZF1 PDLIM5 PRX RIMS1 ZC3H7B

2.70e-0419514676065_UP
DrugDehydrocholic acid [81-23-2]; Down 200; 9.6uM; MCF7; HT_HG-U133A

PTBP3 RPS6KA5 RFTN1 FAM210B SENP6 EDRF1 KDM4B

2.70e-0419514671523_DN
Drugoxaprozin; Down 200; 300uM; MCF7; HT_HG-U133A_EA

STRN3 ARRB1 FAM210B PDCD11 ZC3H7B KDM4B BAHCC1

2.70e-041951467863_DN
Drugradicicol; Up 200; 0.1uM; MCF7; HG-U133A

PTBP3 ABHD3 PDLIM5 AGT VPS13A ATP2B4 KDM4B

2.70e-041951467325_UP
DrugProgesterone [57-83-0]; Down 200; 12.8uM; MCF7; HT_HG-U133A

DOC2A STRN3 ATRX SCLY ASPH VPS13A MMP2

2.70e-0419514673287_DN
DrugSuprofen [40828-46-4]; Up 200; 15.4uM; MCF7; HT_HG-U133A

IKZF1 SLC35G2 ITGB4 ZNF3 ARRB1 ASPH ATP2B4

2.70e-0419514674123_UP
DrugMagnetite Nanoparticles

STRN3 ATRX RPS6KA5 RPS6KA2 IKZF1 KLF4 ZEB2 PDLIM5 ZNF518A DDX46 NRXN3 CADPS AHNAK AGT ASPH LRP1 IFI44L MMP2 MGA DNAJC3

2.71e-04131014620ctd:D058185
DrugTrp-Trp

KNTC1 TRPC5 PDLIM5 RYR1

2.75e-04491464CID000088656
DrugKaempferol [520-18-3]; Up 200; 14uM; MCF7; HT_HG-U133A

AMACR RPS6KA2 IKZF1 KLF4 RFTN1 BUB1 SSX3

2.79e-0419614673579_UP
DrugSulpiride [15676-16-1]; Up 200; 11.8uM; HL60; HG-U133A

ABHD3 CHD1L RGS1 AHNAK IFT122 MYL10 DNAJC3

2.79e-0419614671967_UP
DrugNomifensine maleate [32795-47-4]; Down 200; 11.2uM; PC3; HT_HG-U133A

ATRX TCN1 SCLY SIRT2 BUB1 SENP6 KDM2A

2.79e-0419614675863_DN
DrugTolazamide [1156-19-0]; Down 200; 12.8uM; HL60; HT_HG-U133A

SPN IKZF1 ALS2CL PDLIM5 SERPINI2 FAM210B BUB1

2.79e-0419614672482_DN
DrugDipivefrin hydrochloride [64019-93-8]; Down 200; 10.4uM; MCF7; HT_HG-U133A

MON2 CIDEB PTBP3 ITGB4 ZC3H7B EDRF1 RASAL1

2.79e-0419614676766_DN
DrugEpirizole [18694-40-1]; Up 200; 17uM; PC3; HT_HG-U133A

RPS6KA2 LRP1 SENP6 MMP2 ZC3H7B MYL10 SSX3

2.87e-0419714677292_UP
DrugGemfibrozil [25812-30-0]; Up 200; 16uM; PC3; HT_HG-U133A

PRX ZNF3 PARP6 LRP1 ZC3H7B RASAL1 KDM4B

2.87e-0419714675069_UP
DrugViomycin sulfate [37883-00-4]; Down 200; 5.2uM; HL60; HT_HG-U133A

STRN3 TAF1C IKZF1 ABCB4 AHNAK ZC3H7B MYL10

2.87e-0419714672979_DN
DrugSpaglumic acid [4910-46-7]; Down 200; 13.2uM; MCF7; HT_HG-U133A

PTBP3 STRN3 SPN EMSY ASPH EDRF1 KDM4B

2.87e-0419714677465_DN
DrugMefexamide hydrochloride [3413-64-7]; Down 200; 12.6uM; MCF7; HT_HG-U133A

PTBP3 STRN3 SCLY TESK2 ASPH IFT122 EDRF1

2.87e-0419714677478_DN
Drugsodium 4-phenylbutyrate; Up 200; 1000uM; MCF7; HG-U133A

DOC2A RPS6KA5 ABHD3 APOB RFTN1 ASPH MYL10

2.87e-041971467407_UP
DrugDeltaline [6836-11-9]; Down 200; 7.8uM; HL60; HT_HG-U133A

PTBP3 SPN IKZF1 AHNAK KDM2A CEP131 MYL10

2.87e-0419714672171_DN
Drugvaldecoxib; Up 200; 10uM; PC3; HT_HG-U133A

ITGB4 SLC6A11 ARRB1 PTPRD FAM210B EDRF1 KDM4B

2.87e-0419714676378_UP
DrugIsoconazole [27523-40-6]; Down 200; 9.6uM; HL60; HG-U133A

ABHD3 ALS2CL RGS1 VPS13A KDM2A ZC3H7B ATP2B4

2.87e-0419714671372_DN
DrugGalanthamine hydrobromide [1953-04-4]; Down 200; 10.8uM; HL60; HT_HG-U133A

MON2 PTBP3 STRN3 SPN ALS2CL ITGB4 ASPH

2.87e-0419714672131_DN
DrugMonocrotaline [315-22-0]; Down 200; 12.2uM; MCF7; HT_HG-U133A

MON2 SPN EMSY PDLIM5 RFTN1 ARRB1 ZC3H7B

2.87e-0419714676771_DN
DrugDiazoxide [364-98-7]; Up 200; 17.4uM; MCF7; HT_HG-U133A

PTBP3 STRN3 IKZF1 ASPH SENP6 SSX3 ATP2B4

2.87e-0419714677168_UP
Drugnovobiocin sodium, USP; Up 200; 100uM; MCF7; HG-U133A

TCN1 SPN IKZF1 PRX DMD MYL10 CDH18

2.87e-041971467576_UP
Drugbeta- Belladonnine dichloroethylate [191355-47-2]; Down 200; 6uM; HL60; HT_HG-U133A

DOC2A STRN3 SPN TAF1C AHNAK KDM2A SSX3

2.96e-0419814672164_DN
DrugNitrarine dihydrochloride [20069-05-0]; Down 200; 10.6uM; HL60; HT_HG-U133A

PTBP3 STRN3 TAF1C IKZF1 ARRB1 BUB1 MYL10

2.96e-0419814672188_DN
DrugKynurenine, 3-hydroxy (R,S) [2147-61-7]; Down 200; 17.8uM; PC3; HT_HG-U133A

STRN3 SPN IKZF1 SIRT2 PTPRR LRP1 DNAJC3

2.96e-0419814674681_DN
DrugMeticrane [1084-65-7]; Up 200; 14.6uM; PC3; HT_HG-U133A

STRN3 SLC35G2 TESK2 LRP1 SENP6 MYL10 EDRF1

2.96e-0419814677282_UP
Drug2-propylpentanoic acid; Down 200; 500uM; PC3; HT_HG-U133A

PDLIM5 FAM210B BUB1 ASPH MMP2 MYL10 EDRF1

2.96e-0419814674464_DN
DiseaseRare disease with malignant hyperthermia

CACNA1S SELENON RYR1

4.83e-0741473cv:C5681128
DiseaseMalignant hyperthermia, susceptibility to

CACNA1S RYR1

2.47e-0521472cv:C5437603
DiseaseMalignant hyperthermia

CACNA1S RYR1

2.47e-0521472cv:C5779784
DiseaseMalignant hyperpyrexia due to anesthesia

CACNA1S RYR1

2.47e-0521472C0024591
DiseaseMultiminicore myopathy

SELENON RYR1

2.47e-0521472cv:C0270962
DiseaseCongenital myopathy (disorder)

CACNA1S SELENON RYR1

2.58e-05121473C0270960
DiseaseColorectal Carcinoma

AMACR APOB RRM2 ZEB2 ABCB4 PTPRD BUB1 VPS13A LRP1 KDM2A MMP2 DMD EDRF1

5.27e-0570214713C0009402
Diseasemalignant hyperthermia (is_implicated_in)

CACNA1S RYR1

7.37e-0531472DOID:8545 (is_implicated_in)
Diseasedilated cardiomyopathy 1H (is_marker_for)

TRPC5 AIFM1

7.37e-0531472DOID:0110429 (is_marker_for)
DiseaseCongenital Fiber Type Disproportion

MYL2 SELENON RYR1

9.36e-05181473C0546264
DiseaseCoffin-Lowry syndrome (implicated_via_orthology)

RPS6KA2 RPS6KA3

1.47e-0441472DOID:3783 (implicated_via_orthology)
Diseasehypertrophic cardiomyopathy 10 (implicated_via_orthology)

MYL2 MYL10

2.44e-0451472DOID:0110316 (implicated_via_orthology)
Diseasehyperinsulinemic hypoglycemia (implicated_via_orthology)

HK2 HKDC1

2.44e-0451472DOID:13317 (implicated_via_orthology)
DiseaseNeoplasm Invasiveness

ACO1 RPS6KA3 ZEB2 AHNAK MMP2 DMD

3.31e-041841476C0027626
Diseasecolorectal cancer (is_implicated_in)

IKZF1 JAK1 BUB1 TRPV3 KDM4B

3.58e-041211475DOID:9256 (is_implicated_in)
DiseaseCongenital myopathy with fiber type disproportion

SELENON RYR1

3.65e-0461472cv:C0546264
DiseaseHailey-Hailey disease (implicated_via_orthology)

ATP2B2 ATP2B4

3.65e-0461472DOID:0050429 (implicated_via_orthology)
DiseaseHereditary, Type VII, Motor and Sensory Neuropathy

AMACR PRX

3.65e-0461472C0019816
DiseaseHereditary Motor and Sensory Neuropathies

AMACR PRX

3.65e-0461472C0027888
DiseaseNeointima Formation

AGT MMP2

3.65e-0461472C2936381
DiseaseNeointima

AGT MMP2

3.65e-0461472C2936380
Diseaseprogressive supranuclear palsy

PIK3C2G ATP2B2 ATP2B4

4.92e-04311473MONDO_0019037
DiseaseColorectal Neoplasms

AMACR RRM2 ABCB4 PTPRD BUB1 KDM2A MMP2

4.96e-042771477C0009404
DiseaseShwachman-Diamond syndrome (implicated_via_orthology)

SRP54 SERPINI2

5.09e-0471472DOID:0060479 (implicated_via_orthology)
DiseaseDejerine-Sottas Disease (disorder)

AMACR PRX

5.09e-0471472C0011195
Diseasecysteine-rich with EGF-like domain protein 1 measurement

SLC6A11 ATP2B2 ATP2B4

5.40e-04321473EFO_0021870
DiseaseMuscular Dystrophy

SELENON DMD

6.77e-0481472C0026850
DiseaseDuchenne muscular dystrophy (implicated_via_orthology)

CACNA1S SLC6A5 DMD

7.67e-04361473DOID:11723 (implicated_via_orthology)
Diseasematurity-onset diabetes of the young (implicated_via_orthology)

HK2 HKDC1

1.08e-03101472DOID:0050524 (implicated_via_orthology)
Diseasetemporomandibular joint disorder

DMD BAHCC1

1.08e-03101472EFO_0005279
DiseaseTumoral calcinosis

SPN MMP2 DMD

1.21e-03421473C0263628
DiseaseCalcinosis

SPN MMP2 DMD

1.21e-03421473C0006663
DiseaseMicrocalcification

SPN MMP2 DMD

1.21e-03421473C0521174
Diseasefear of severe pain measurement

PTPRR MYOCD

1.32e-03111472EFO_0008338
DiseaseAlzheimer disease, APOE carrier status

RPS6KA2 FAM135B FAM210B KDM4B

1.49e-03981474EFO_0007659, MONDO_0004975
Diseasemelanoma

ERCC3 SLC35G2 SLC6A11 HOXD12 KDM4B CDK2

1.56e-032481476C0025202
DiseaseIgG galactosylation measurement

IKZF1 CEP131

1.57e-03121472EFO_0008425
DiseaseCongenital muscular dystrophy

SELENON RYR1

1.57e-03121472cv:C0699743
DiseasePrecursor B-Cell Lymphoblastic Leukemia-Lymphoma

IKZF1 MGA

1.57e-03121472C0023485
Diseasefocal segmental glomerulosclerosis (biomarker_via_orthology)

AGT MMP2

1.57e-03121472DOID:1312 (biomarker_via_orthology)
DiseaseLiver Cirrhosis

ABCB4 ARRB1 AGT MMP2

1.78e-031031474C0023890
DiseaseAutosomal Dominant Myotubular Myopathy

SELENON RYR1

1.85e-03131472C3661489
DiseaseCentronuclear myopathy

SELENON RYR1

1.85e-03131472C0175709
DiseaseX-linked centronuclear myopathy

SELENON RYR1

1.85e-03131472C0410203
DiseaseMyopathy, Centronuclear, 1

SELENON RYR1

1.85e-03131472C4551952
Diseaseskin melanoma (is_marker_for)

AGT MMP2

1.85e-03131472DOID:8923 (is_marker_for)
DiseaseCongenital Structural Myopathy

SELENON RYR1

1.85e-03131472C0752282
DiseaseFibrosis, Liver

ABCB4 ARRB1 AGT MMP2

1.91e-031051474C0239946
Diseasediabetic retinopathy (is_implicated_in)

APOB AGT MMP2

2.00e-03501473DOID:8947 (is_implicated_in)
DiseaseMyopathy, Centronuclear, Autosomal Dominant

SELENON RYR1

2.16e-03141472C1834558
DiseaseTubular Aggregate Myopathy

SELENON RYR1

2.16e-03141472C0410207
DiseaseAntihypertensive use measurement

RPS6KA3 INO80 AGT ATP2B2 ATP2B4 KDM4B

2.18e-032651476EFO_0009927
DiseaseAlcoholic Intoxication, Chronic

ANKK1 NRXN3 TESK2 ASTN1 MMP2 CDH18

2.31e-032681476C0001973
DiseaseGlioblastoma Multiforme

ATRX RPS6KA3 MMP2 CDK2

2.34e-031111474C1621958
DiseaseAutosomal Recessive Centronuclear Myopathy

SELENON RYR1

2.48e-03151472C3645536
Diseaseamenorrhea, response to antineoplastic agent

APOB RIMS1

2.48e-03151472EFO_0010269, GO_0097327
DiseaseNecrosis

AIFM1 AGT DMD

2.63e-03551473C0027540
Diseasehyperglycemia (implicated_via_orthology)

HK2 HKDC1

3.19e-03171472DOID:4195 (implicated_via_orthology)
DiseaseAPOE carrier status, dementia

RPS6KA2 FAM135B FAM210B

3.70e-03621473EFO_0007659, MONDO_0001627
Diseaseinosine measurement

RPS6KA2 DMD

3.99e-03191472EFO_0010503
DiseaseCardiomyopathies

MYL2 AGT MYOCD DMD

4.13e-031301474C0878544
Diseasebody weight

KNTC1 PTBP3 RPS6KA5 HECTD4 CHD1L NRXN3 PTPRR CADPS SENP6 KDM2A DMD MGA ATP2B4 KDM4B

4.27e-03126114714EFO_0004338
Diseasemyocardial infarction (implicated_via_orthology)

RYR1 AGT MMP2

4.41e-03661473DOID:5844 (implicated_via_orthology)
DiseaseFetal Growth Retardation

AGT MMP2

4.42e-03201472C0015934
Diseaseradiation-induced disorder

DCHS2 PDLIM5 PTPRD

4.60e-03671473EFO_0009565
DiseaseSchizophrenia

ANKK1 AMACR ADNP2 ALS2CL PDLIM5 SLC6A11 NRXN3 NRXN2 PIK3C3 SLC6A5 LRP1

4.81e-0388314711C0036341
Diseasefumarate measurement

RPS6KA2 RFTN1

4.86e-03211472EFO_0010480
DiseaseInfiltrating duct carcinoma of female breast

ANKK1 TESK2

4.86e-03211472C3165106

Protein segments in the cluster

PeptideGeneStartEntry
SNPSVMLGAGLLAKK

ACO1

441

P21399
DLTLMGKGKVTFPNG

ALS2CL

536

Q60I27
ALLMGDKDFSPKLGR

BAHCC1

2256

Q9P281
GKKMLDITPGCKSLF

CFAP54

1231

Q96N23
MSASAVFILDVKGKP

AP1M2

1

Q9Y6Q5
GTIKLKVFLSGMPEL

AP1M2

196

Q9Y6Q5
DLGQSIDMKLFPKGT

BUB1

946

O43683
EKGNMGKILPEYLSN

AIFM1

336

O95831
KGLGLKSDELPNQMS

AMACR

246

Q9UHK6
RKQGIMSFLEGKEPS

ANKK1

736

Q8NFD2
EMNRLFSGKGDITKP

FBXW10

236

Q5XX13
GKIGSKTPLMAAATF

ABHD3

231

Q8WU67
MKIPKFTFSGRELVG

AHNAK

5661

Q09666
LGNIFEKLGICSMPK

AADACL4

56

Q5VUY2
GLAVMDKAKGLFLPE

ASPH

601

Q12797
ALKEKGQGPMFLDAD

DMD

896

P11532
FLAMGKSKAALPDLT

DNAJC3

81

Q13217
MGDKGTRVFKKASPN

ARRB1

1

P49407
PALKKADVGFAMGIA

ATP2B2

826

Q01814
PALKKADVGFAMGIA

ATP2B4

791

P23634
KSGMDLTPGSDNAKL

ASTN1

281

O14525
VKKLSLLGGALPMFE

ATG4B

336

Q9Y4P1
KPSVLLGFDMSELKN

ADNP2

1106

Q6IQ32
QGKMKGFSLLAEPQE

AGT

276

P01019
KMQKFFGLPQTGDLD

MMP2

76

P08253
VGKNDFLGMVEFSPK

RASAL1

206

O95294
EISKAPKSGFEGMFI

RANBP2

1766

P49792
DGEPMKGVKFLLFSS

NOMO3

226

P69849
EPLSGKMEIFTLFNK

RFTN1

271

Q14699
GMFFSANPKELKGTT

RGS1

16

Q08116
KMENGQITPDGFLSK

INTS6L

681

Q5JSJ4
GIKLIMEFLPSGSLK

JAK1

951

P23458
PMGKNISIIFKAGDD

PIK3C2G

911

O75747
SFPALGTGNMEIKKE

PARP9

426

Q8IXQ6
RMVISGGNFKPDTLK

INO80

1246

Q9ULG1
PRFLVMKGQEGAASK

SLC2A12

221

Q8TD20
FGKFGPALSVKVMTD

PABPC1

211

P11940
VFLTMFGEKLKGADP

MYL2

81

P10916
KSIPFGMKSAVERGL

ANKAR

496

Q7Z5J8
SMPVSKGGEFKLQKL

CADPS

356

Q9ULU8
DGEPMKGVKFLLFSS

NOMO2

226

Q5JPE7
MGKFVLKASLSAPGS

KLF4

226

O43474
KDFLGSGDPKETKML

IFT122

736

Q9HBG6
EFLPKKISGDMRGIQ

MGA

2741

Q8IWI9
LAMEELKSGSGPSLK

SPN

356

P16150
GPEGLEKQMALFLDK

EDRF1

646

Q3B7T1
MLTGTLPFQGKDRKE

RPS6KA3

261

P51812
KGIALDPAMGKVFFT

LRP1

326

Q07954
SVKDGKNGKSLPFML

IFI44L

246

Q53G44
VPVGGMADLNFKISK

HECTD2

716

Q5U5R9
MFTSKLKEGSLGINP

FSIP2

3166

Q5CZC0
IDMGSLNPGKQLFEK

HK2

281

P52789
KLMLQEPLEKLGFGD

COX19

66

Q49B96
KLKGETMDLQHGSPF

LDHAL6B

106

Q9BYZ2
KLGGFPISLAMATKL

MINDY4B

91

A8MYZ0
FMKILGKGKSESELP

OR2M2

301

Q96R28
SGVDMPAILLKLGFK

FAM210B

121

Q96KR6
EGDPKMKLQGDLSFR

NRXN2

471

Q9P2S2
VQAMPGFKGLILDLK

NRXN3

166

Q9Y4C0
DGEPMKGVKFLLFSS

NOMO1

226

Q15155
AGEGQAPSTFSKLKM

KDM4B

591

O94953
ELFCSSPKEGMIKGL

KNTC1

1936

P50748
MSPVFGLLVDKTGKN

MFSD1

316

Q9H3U5
GLLTVDPNKRLKMSG

RPS6KA5

666

O75582
VFLTMFGEKLKGTDP

MYL10

141

Q9BUA6
IGQKFPKSMEISLSG

AP5M1

391

Q9H0R1
GKDFNMPLTISSLKD

PDLIM5

21

Q96HC4
MPLTISSLKDGGKAA

PDLIM5

26

Q96HC4
SSMPQKFLGDKGLSD

IKZF1

276

Q13422
FLMGCGTKEPKITQL

MON2

71

Q7Z3U7
TPKVMVGFLTGDKFI

OR5B12

76

Q96R08
PFRLGTGANMEKVVK

HECTD4

1556

Q9Y4D8
LKPSFSDGLKMDAGI

ITGB4

436

P16144
PFMLSELQDGKSKIV

ALAS2

71

P22557
PLGKMSDVTLLKIGS

MYOCD

816

Q8IZQ8
LSGKKDGLVPMFINT

MAN1B1

431

Q9UKM7
FGKFGPALSVKVMTD

PABPC3

211

Q9H361
MKLPQKFDTLVGERG

ABCB4

516

P21439
SGKEKAFIATQGPMI

PTPRR

456

Q15256
LSDGKFFKMNPNTGE

DCHS2

1231

Q6V1P9
TTMPKDSGALLGLKV

RIMS1

606

Q86UR5
PFGGKSSRDLKMLET

APOB

1301

P04114
EKKGLTMRFNIPTGT

ATRX

2281

P46100
IMATLGFGDSPKAEK

FBF1

211

Q8TES7
TDFSSQKGVKGLPLM

GRHL2

376

Q6ISB3
LIFKNSDGLGIKMPD

KDM2A

76

Q9Y2K7
LRAKGLKPMDFNGLA

DOC2A

111

Q14183
PMSSKGAGLDVKALR

CACNA1S

151

Q13698
KMKDLSLGGVLLFPV

CHD1L

771

Q86WJ1
PDGMKDLDAIKLFVG

CELF5

36

Q8N6W0
GFKDDTKGPLNLNMT

HOXD12

161

P35452
NTERPGMLDFTGKAK

DBI

41

P07108
LGPFKDATMLKIIVG

CDH18

361

Q13634
ETKFPLSKGLEMGLE

EFHB

61

Q8N7U6
PKKALATSMLTGEAG

EMSY

1171

Q7Z589
RKLSKTGVPDGIMQF

ERCC3

141

P19447
LPGGKLDFLMSEKNQ

FAM135B

1166

Q49AJ0
AKTGSGKTIAFLLPM

DDX46

416

Q7L014
DLKKFMDASALTGIP

CDK2

86

P24941
KSFDIGVNKDSLMPL

ENPP6

101

Q6UWR7
MKSGPEIVKAGLRSF

RYR1

3081

P21817
TDFLMLFEGSPSGKK

CEP131

96

Q9UPN4
FPIIQDSMLKGKLGV

PARP6

186

Q2NL67
KPAFIGKTNLDGMIT

PTPRD

1111

P23468
LDGLKKLGSSKDMQP

NRIP3

46

Q9NQ35
MGSGPKESALKALNS

SMG8

871

Q8ND04
KYGTELNQGDLKMPT

STRN3

136

Q13033
LPASGLDIFGDLKKM

SEC11C

11

Q9BY50
KTQPFISKLLGMGDI

SRP54

286

P61011
KNMIDPLGTSSLGLK

SLC6A5

771

Q9Y345
LNPGKQLFEKMISGL

HKDC1

286

Q2TB90
ATKNRVGFLKEMGTP

RPL7L1

226

Q6DKI1
PLGKLMLENFKLEGA

TAF1C

121

Q15572
GNFMEENPKKGLLSE

SLC35G2

46

Q8TBE7
LSDKSLSILKMVGPG

PIRT

81

P0C851
LMPAQLFFKTEDGGK

PIK3C3

616

Q8NEB9
EAMTKLGFKAILPSF

SSX3

56

Q99909
NKEKAGQSDPFLGMI

SIRT2

286

Q8IXJ6
MGKEGNYDLKLAELP

HERC2P3

646

Q9BVR0
DFFPKDDKGNMISGK

AKR1B15

121

C9JRZ8
SMSCDFQGLGPKKVL

CIDEB

161

Q9UHD4
KAKESGMALPQGRLT

ZNF610

11

Q8N9Z0
DLTGIFMHGKIPTLK

PRPF8

1556

Q6P2Q9
GLSGLAPKAIMSDKF

PDCD11

751

Q14690
SLAKMIGGKPQDIIF

SCLY

81

Q96I15
EKPLNGIGMSKSSLR

ZNF3

421

P17036
KKATPRMIGLTVGFD

VPS13A

1466

Q96RL7
VPDLSSDLGMNIFKK

UNC80

431

Q8N2C7
MGFTIDIKSFLKPGE

PSPC1

61

Q8WXF1
LKKRGLMPGLTFSNE

RRM2

246

P31350
LKMPSFGLARGKEAE

PRX

1061

Q9BXM0
LPETMTKSKDGFLGV

SELENON

166

Q9NZV5
MSLGTKGLKVNLFPG

TNKS1BP1

1636

Q9C0C2
LPALMGKTFLDINKD

TCN1

291

P20061
MTAEKALPLGNGKAA

SLC6A11

1

P48066
LMEKELPGFLQSGKD

S100P

36

P25815
ESFKTLKGNPIGLNM

SENP6

96

Q9GZR1
KIKDMFSGEEFGPLT

SERPINI2

161

O75830
EKMPRISGFGTLLKT

ZNF518A

876

Q6AHZ1
GKGPSIKQFMDIFSL

NT5DC2

176

Q9H857
PFGKVTNLLMLKGKS

PTBP3

81

O95758
MKGSELTPKQEFFKG

ZKSCAN7

276

Q9P0L1
GLTPLQLAAKMGKAE

TRPV3

341

Q8NET8
GPGMTLQLKLKESFL

SFTA2

21

Q6UW10
SFMGPSLKKLGLLFS

TRPC5

836

Q9UL62
EKKSGLSVRFADMPG

WBP11

301

Q9Y2W2
GKPLSMSEQTGLLKI

ZEB2

376

O60315
QDLMGGKIKFFDLPS

TESK2

406

Q96S53
KGIPQTMAAFGLKDS

VN1R3

61

Q9BXE9
FGLVMDPSKKLAASV

ZC3H7B

321

Q9UGR2
EMLTGSLPFQGKDRK

RPS6KA2

251

Q15349
ILKAKLGMPQFLSGE

RPS6KA2

271

Q15349