Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	RNA polymerase II transcription regulatory region sequence-specific DNA binding	ZNF7 ZNF708 ZNF134 ZNF627 ZNF716 ZNF555 ZNF154 VEZF1 ZNF684 MTF2 MTF1 ZNF268 ZNF728 ZNF655 ZNF587 ZNF408 RBAK ZNF256 ZNF737 ZNF814 ZNF727 ZNF208 ZNF79 ZNF80 ZNF217 ZNF736 ZNF417 ZNF850 ZNF416 ZNF548 ZNF595 ZNF669 ZNF461 ZNF77 ZNF44 ZNF445 ZNF3	7.61e-22	1459	78	37	GO:0000977
GeneOntologyMolecularFunction	DNA-binding transcription factor activity, RNA polymerase II-specific	ZNF7 ZNF708 ZNF134 ZNF627 ZNF716 ZNF555 ZNF154 VEZF1 ZNF684 MTF1 ZNF268 ZNF728 ZNF655 ZNF587 ZNF408 RBAK ZNF256 ZNF737 ZNF814 ZNF727 ZNF208 ZNF79 ZNF80 ZNF217 ZNF736 ZNF417 ZNF850 ZNF416 ZNF548 ZNF595 ZNF669 ZNF461 ZNF77 ZNF44 ZNF445 ZNF3	2.94e-21	1412	78	36	GO:0000981
GeneOntologyMolecularFunction	RNA polymerase II cis-regulatory region sequence-specific DNA binding	ZNF7 ZNF708 ZNF134 ZNF716 ZNF154 MTF1 ZNF268 ZNF728 ZNF655 ZNF587 ZNF408 RBAK ZNF256 ZNF737 ZNF814 ZNF727 ZNF208 ZNF217 ZNF736 ZNF417 ZNF850 ZNF416 ZNF548 ZNF595 ZNF461 ZNF445 ZNF3	6.60e-14	1244	78	27	GO:0000978
GeneOntologyMolecularFunction	cis-regulatory region sequence-specific DNA binding	ZNF7 ZNF708 ZNF134 ZNF716 ZNF154 MTF1 ZNF268 ZNF728 ZNF655 ZNF587 ZNF408 RBAK ZNF256 ZNF737 ZNF814 ZNF727 ZNF208 ZNF217 ZNF736 ZNF417 ZNF850 ZNF416 ZNF548 ZNF595 ZNF461 ZNF445 ZNF3	1.11e-13	1271	78	27	GO:0000987
GeneOntologyMolecularFunction	DNA-binding transcription activator activity, RNA polymerase II-specific	VEZF1 MTF1 ZNF268 ZNF814 ZNF727 ZNF208 ZNF736 ZNF850 ZNF445 ZNF3	6.31e-05	560	78	10	GO:0001228
GeneOntologyMolecularFunction	DNA-binding transcription activator activity	VEZF1 MTF1 ZNF268 ZNF814 ZNF727 ZNF208 ZNF736 ZNF850 ZNF445 ZNF3	6.89e-05	566	78	10	GO:0001216
GeneOntologyMolecularFunction	monosaccharide binding	SELP IGF2R GYG1 DBH	5.24e-04	95	78	4	GO:0048029
Domain	zf-C2H2	ZNF7 ZNF708 ZNF134 ZNF627 ZNF716 ZNF555 ZNF154 VEZF1 ZNF684 MTF1 ZNF268 ZNF728 ZNF655 ZNF587 ZNF408 RBAK ZNF256 ZNF737 ZNF814 ZNF727 ZNF208 ZNF79 ZNF80 ZNF217 ZNF736 ZNF417 ZNF850 ZNF416 ZNF548 ZNF595 ZNF669 ZNF461 ZNF77 ZNF44 ZNF445 ZNF3	1.99e-31	693	76	36	PF00096
Domain	KRAB	ZNF7 ZNF708 ZNF627 ZNF716 ZNF555 ZNF154 ZNF684 ZNF268 ZNF728 ZNF587 RBAK ZNF256 ZNF737 ZNF814 ZNF727 ZNF208 ZNF79 ZNF736 ZNF417 ZNF850 ZNF416 ZNF548 ZNF595 ZNF669 ZNF461 ZNF77 ZNF44 ZNF445 ZNF3	1.83e-30	358	76	29	PS50805
Domain	KRAB	ZNF7 ZNF708 ZNF627 ZNF716 ZNF555 ZNF154 ZNF684 ZNF268 ZNF728 ZNF587 RBAK ZNF256 ZNF737 ZNF814 ZNF727 ZNF208 ZNF79 ZNF736 ZNF417 ZNF850 ZNF416 ZNF548 ZNF595 ZNF669 ZNF461 ZNF77 ZNF44 ZNF445 ZNF3	1.83e-30	358	76	29	PF01352
Domain	-	ZNF7 ZNF708 ZNF134 ZNF627 ZNF716 ZNF555 ZNF154 VEZF1 ZNF684 MTF1 ZNF268 ZNF728 ZNF655 ZNF587 ZNF408 RBAK ZNF256 ZNF737 ZNF814 ZNF727 ZNF208 ZNF79 ZNF80 ZNF217 ZNF736 ZNF417 ZNF850 ZNF416 ZNF548 ZNF669 ZNF461 ZNF77 ZNF44 ZNF445 ZNF3	2.37e-30	679	76	35	3.30.160.60
Domain	KRAB	ZNF7 ZNF708 ZNF627 ZNF716 ZNF555 ZNF154 ZNF684 ZNF268 ZNF728 ZNF587 RBAK ZNF256 ZNF737 ZNF814 ZNF727 ZNF208 ZNF79 ZNF736 ZNF417 ZNF850 ZNF416 ZNF548 ZNF595 ZNF669 ZNF461 ZNF77 ZNF44 ZNF445 ZNF3	4.44e-30	369	76	29	SM00349
Domain	KRAB	ZNF7 ZNF708 ZNF627 ZNF716 ZNF555 ZNF154 ZNF684 ZNF268 ZNF728 ZNF587 RBAK ZNF256 ZNF737 ZNF814 ZNF727 ZNF208 ZNF79 ZNF736 ZNF417 ZNF850 ZNF416 ZNF548 ZNF595 ZNF669 ZNF461 ZNF77 ZNF44 ZNF445 ZNF3	4.81e-30	370	76	29	IPR001909
Domain	Znf_C2H2/integrase_DNA-bd	ZNF7 ZNF708 ZNF134 ZNF627 ZNF716 ZNF555 ZNF154 VEZF1 ZNF684 MTF1 ZNF268 ZNF728 ZNF655 ZNF587 ZNF408 RBAK ZNF256 ZNF737 ZNF814 ZNF727 ZNF208 ZNF79 ZNF80 ZNF217 ZNF736 ZNF417 ZNF850 ZNF416 ZNF548 ZNF669 ZNF461 ZNF77 ZNF44 ZNF445 ZNF3	5.02e-30	694	76	35	IPR013087
Domain	ZINC_FINGER_C2H2_2	ZNF7 ZNF708 ZNF134 ZNF627 ZNF716 ZNF555 ZNF154 VEZF1 ZNF684 MTF1 ZNF268 ZNF728 ZNF655 ZNF587 ZNF408 RBAK ZNF256 ZNF737 ZNF814 ZNF727 ZNF208 ZNF79 ZNF80 ZNF217 ZNF736 ZNF417 ZNF850 ZNF416 ZNF548 ZNF595 ZNF669 ZNF461 ZNF77 ZNF44 ZNF445 ZNF3	1.03e-29	775	76	36	PS50157
Domain	ZINC_FINGER_C2H2_1	ZNF7 ZNF708 ZNF134 ZNF627 ZNF716 ZNF555 ZNF154 VEZF1 ZNF684 MTF1 ZNF268 ZNF728 ZNF655 ZNF587 ZNF408 RBAK ZNF256 ZNF737 ZNF814 ZNF727 ZNF208 ZNF79 ZNF80 ZNF217 ZNF736 ZNF417 ZNF850 ZNF416 ZNF548 ZNF595 ZNF669 ZNF461 ZNF77 ZNF44 ZNF445 ZNF3	1.13e-29	777	76	36	PS00028
Domain	Znf_C2H2	ZNF7 ZNF708 ZNF134 ZNF627 ZNF716 ZNF555 ZNF154 VEZF1 ZNF684 MTF1 ZNF268 ZNF728 ZNF655 ZNF587 ZNF408 RBAK ZNF256 ZNF737 ZNF814 ZNF727 ZNF208 ZNF79 ZNF80 ZNF217 ZNF736 ZNF417 ZNF850 ZNF416 ZNF548 ZNF595 ZNF669 ZNF461 ZNF77 ZNF44 ZNF445 ZNF3	3.91e-29	805	76	36	IPR007087
Domain	ZnF_C2H2	ZNF7 ZNF708 ZNF134 ZNF627 ZNF716 ZNF555 ZNF154 VEZF1 ZNF684 MTF1 ZNF268 ZNF728 ZNF655 ZNF587 ZNF408 RBAK ZNF256 ZNF737 ZNF814 ZNF727 ZNF208 ZNF79 ZNF80 ZNF217 ZNF736 ZNF417 ZNF850 ZNF416 ZNF548 ZNF595 ZNF669 ZNF461 ZNF77 ZNF44 ZNF445 ZNF3	4.46e-29	808	76	36	SM00355
Domain	Znf_C2H2-like	ZNF7 ZNF708 ZNF134 ZNF627 ZNF716 ZNF555 ZNF154 VEZF1 ZNF684 MTF1 ZNF268 ZNF728 ZNF655 ZNF587 ZNF408 RBAK ZNF256 ZNF737 ZNF814 ZNF727 ZNF208 ZNF79 ZNF80 ZNF217 ZNF736 ZNF417 ZNF850 ZNF416 ZNF548 ZNF669 ZNF461 ZNF77 ZNF44 ZNF445 ZNF3	5.45e-28	796	76	35	IPR015880
Domain	zf-C2H2_6	ZNF627 ZNF555 ZNF154 ZNF684 ZNF728 ZNF587 ZNF408 ZNF256 ZNF737 ZNF814 ZNF727 ZNF208 ZNF79 ZNF80 ZNF736 ZNF417 ZNF850 ZNF416 ZNF548 ZNF669 ZNF461 ZNF77 ZNF44 ZNF445	1.84e-24	314	76	24	PF13912
Domain	Selectin_superfamily	SELE SELP	4.89e-05	3	76	2	IPR002396
Domain	EGF	MEP1A SELE SELP TECTA STAB1	1.63e-04	126	76	5	PF00008
Domain	EGF	MEP1A SELE SELP FBN2 TECTA STAB1	3.90e-04	235	76	6	SM00181
Domain	EGF-like_dom	MEP1A SELE SELP FBN2 TECTA STAB1	5.30e-04	249	76	6	IPR000742
Pathway	REACTOME_RNA_POLYMERASE_II_TRANSCRIPTION	ZNF708 PPP2R1A ZNF627 ZNF716 ZNF555 ZNF154 ZNF684 ZNF268 ZNF655 ZNF587 ZNF256 ZNF737 ZNF727 ZNF208 ZNF79 ZNF736 ZNF417 ZNF416 ZNF548 ZNF595 ZNF669 ZNF461 ZNF77 ZNF445 ZNF3	1.53e-09	1387	67	25	M734
Pathway	REACTOME_GENERIC_TRANSCRIPTION_PATHWAY	PPP2R1A ZNF268 ZNF655 ZNF814 ZNF727 ZNF208 ZNF736 PDPK2P ZNF850 ZNF416 ZNF595 ZNF44 ZNF445 ZNF3	1.19e-05	768	67	14	MM14851
Pathway	REACTOME_GENE_EXPRESSION_TRANSCRIPTION	PPP2R1A MTF2 ZNF268 ZNF655 ZNF814 ZNF727 ZNF208 ZNF736 PDPK2P ZNF850 ZNF416 ZNF595 ZNF44 ZNF445 ZNF3	7.01e-05	1022	67	15	MM15436
Pubmed	Acetylation-Mimic Mutation of TRIM28-Lys304 to Gln Attenuates the Interaction with KRAB-Zinc-Finger Proteins and Affects Gene Expression in Leukemic K562 Cells.	ZNF7 ZNF708 ZNF627 ZNF555 ZNF684 ZNF728 ZNF655 ZNF587 ZNF737 ZNF208 ZNF736 ZNF417 ZNF595 ZNF669 ZNF77 ZNF44 ZNF445	3.33e-23	181	78	17	37372979
Pubmed	Rapid and efficient cloning of cDNAs encoding Krüppel-like zinc finger proteins by degenerate PCR.	ZNF7 ZNF814 ZNF727 ZNF208 ZNF736 ZNF850 ZNF445	1.72e-11	49	78	7	9630514
Pubmed	Regulator of sex-limitation (Rsl) encodes a pair of KRAB zinc-finger genes that control sexually dimorphic liver gene expression.	ZNF716 ZNF727 ZNF208 ZNF736 ZNF595	5.67e-09	29	78	5	14563677
Pubmed	Chromosomal localization of four human zinc finger cDNAs.	ZNF79 ZNF80 ZNF77	1.08e-07	5	78	3	8478004
Pubmed	Emergence of the ZNF91 Krüppel-associated box-containing zinc finger gene family in the last common ancestor of anthropoidea.	ZNF7 ZNF814 ZNF850 ZNF595	1.10e-07	20	78	4	7479878
Pubmed	Activation of the c-H-ras proto-oncogene by retrovirus insertion and chromosomal rearrangement in a Moloney leukemia virus-induced T-cell leukemia.	ZNF7 ZNF814 ZNF850 ZNF595	1.10e-07	20	78	4	2542606
Pubmed	Multiple genes encoding zinc finger domains are expressed in human T cells.	ZNF7 ZNF708 ZNF44 ZNF3	7.03e-07	31	78	4	2288909
Pubmed	Resolution of cell fate decisions revealed by single-cell gene expression analysis from zygote to blastocyst.	ZNF7 ZNF716 VEZF1 MTF2 MTF1 ZNF655 RBAK ZNF208 ZNF595 ZNF445 ZNF3	1.88e-06	808	78	11	20412781
Pubmed	Enforced fucosylation of neonatal CD34+ cells generates selectin ligands that enhance the initial interactions with microvessels but not homing to bone marrow.	SELE SELP	4.97e-06	2	78	2	15367439
Pubmed	Anti-P- and E-selectin therapy prevents abortion in the CBA/J x DBA/2J combination by blocking the migration of Th1 lymphocytes into the foetal-maternal interface.	SELE SELP	4.97e-06	2	78	2	16579979
Pubmed	Circulating levels of P-selectin and E-selectin relate to cardiovascular magnetic resonance-derived aortic characteristics in young adults from the general population, a cross-sectional study.	SELE SELP	4.97e-06	2	78	2	30068374
Pubmed	E and P selectins are not required for resistance to severe murine lyme arthritis.	SELE SELP	4.97e-06	2	78	2	9712820
Pubmed	The selectins E and P in normal labour. A preliminary report on evaluation of their prognostic values for preeclampsia.	SELE SELP	4.97e-06	2	78	2	18217430
Pubmed	Infection-stimulated infraosseus inflammation and bone destruction is increased in P-/E-selectin knockout mice.	SELE SELP	4.97e-06	2	78	2	10447722
Pubmed	E-selectin and P-selectin expression in endothelium of leprosy skin lesions.	SELE SELP	4.97e-06	2	78	2	26051909
Pubmed	Overlapping roles for endothelial selectins in murine hematopoietic stem/progenitor cell homing to bone marrow.	SELE SELP	4.97e-06	2	78	2	23499761
Pubmed	Complexity within the plasma cell compartment of mice deficient in both E- and P-selectin: implications for plasma cell differentiation.	SELE SELP	4.97e-06	2	78	2	12881311
Pubmed	E-/P-selectins and colon carcinoma metastasis: first in vivo evidence for their crucial role in a clinically relevant model of spontaneous metastasis formation in the lung.	SELE SELP	4.97e-06	2	78	2	20010946
Pubmed	Heterogeneous effect of two selectin gene polymorphisms on coronary artery disease risk: a meta-analysis.	SELE SELP	4.97e-06	2	78	2	24498435
Pubmed	Cloning of the mouse endothelial selectins. Expression of both E- and P-selectin is inducible by tumor necrosis factor alpha.	SELE SELP	4.97e-06	2	78	2	1378846
Pubmed	Angiogenesis in P- and E-selectin-deficient mice.	SELE SELP	4.97e-06	2	78	2	9789257
Pubmed	E- and P-selectins synergistically inhibit bleomycin-induced pulmonary fibrosis.	SELE SELP	4.97e-06	2	78	2	16936251
Pubmed	Inhibition of delayed-type contact hypersensitivity in mice deficient in both E-selectin and P-selectin.	SELE SELP	4.97e-06	2	78	2	8874194
Pubmed	Cytokine-induced meningitis is dramatically attenuated in mice deficient in endothelial selectins.	SELE SELP	4.97e-06	2	78	2	8647940
Pubmed	Increased soluble selectins as a reflection of activated platelets and endothelium in Legg-Calve-Perthes disease.	SELE SELP	4.97e-06	2	78	2	25000467
Pubmed	Molecular mechanisms underlying IL-4-induced leukocyte recruitment in vivo: a critical role for the alpha 4 integrin.	SELE SELP	4.97e-06	2	78	2	10477616
Pubmed	Adhesion of small cell lung cancer cells to E- and P-selectin under physiological flow conditions: implications for metastasis formation.	SELE SELP	4.97e-06	2	78	2	21544708
Pubmed	E- and P-selectins are essential for the development of cockroach allergen-induced airway responses.	SELE SELP	4.97e-06	2	78	2	12165540
Pubmed	Serum adhesion molecules in acute pancreatitis: time course and early assessment of disease severity.	SELE SELP	4.97e-06	2	78	2	18580442
Pubmed	Differential expression of E- and P-selectin in the microvasculature of sickle cell transgenic mice.	SELE SELP	4.97e-06	2	78	2	15280076
Pubmed	E and P Selectins as Potential Markers in the Assessment of the Severity of Acute Pancreatitis.	SELE SELP	4.97e-06	2	78	2	29517629
Pubmed	Accelerated development of arthritis in mice lacking endothelial selectins.	SELE SELP	4.97e-06	2	78	2	16207337
Pubmed	Macrophages, not neutrophils, infiltrate skeletal muscle in mice deficient in P/E selectins after mechanical reloading.	SELE SELP	4.97e-06	2	78	2	12829442
Pubmed	Impaired eosinophil recruitment to the cornea in P-selectin-deficient mice in Onchocerca volvulus keratitis (River blindness).	SELE SELP	4.97e-06	2	78	2	11053286
Pubmed	Contribution of selectin ligands to eosinophil recruitment into the skin of patients with atopic dermatitis.	SELE SELP	4.97e-06	2	78	2	11981814
Pubmed	Susceptibility to infection and altered hematopoiesis in mice deficient in both P- and E-selectins.	SELE SELP	4.97e-06	2	78	2	8598043
Pubmed	Phase-dependent roles of E-selectin during chronic contact hypersensitivity responses.	SELE SELP	4.97e-06	2	78	2	17456770
Pubmed	E-selectin gene S128R polymorphism is associated with poor prognosis in patients with stage II or III colorectal cancer.	SELE SELP	4.97e-06	2	78	2	19361981
Pubmed	Overlapping functions of E- and P-selectin in neutrophil recruitment during acute inflammation.	SELE SELP	4.97e-06	2	78	2	9746773
Pubmed	Migration of activated CD8(+) T lymphocytes to sites of viral infection does not require endothelial selectins.	SELE SELP	4.97e-06	2	78	2	10666212
Pubmed	The anti-inflammatory effects of a selectin ligand mimetic, TBC-1269, are not a result of competitive inhibition of leukocyte rolling in vivo.	SELE SELP	4.97e-06	2	78	2	15466915
Pubmed	Differential role of E-selectin and P-selectin in T lymphocyte migration to cutaneous inflammatory reactions induced by cytokines.	SELE SELP	4.97e-06	2	78	2	12096034
Pubmed	A critical temporal window for selectin-dependent CD4+ lymphocyte homing and initiation of late-phase inflammation in contact sensitivity.	SELE SELP	4.97e-06	2	78	2	15117973
Pubmed	Regulatory T cells dynamically regulate selectin ligand function during multiple challenge contact hypersensitivity.	SELE SELP	4.97e-06	2	78	2	25274531
Pubmed	Th1 cell-mediated resistance to cutaneous infection with Leishmania major is independent of P- and E-selectins.	SELE SELP	4.97e-06	2	78	2	14568948
Pubmed	Infectious susceptibility and severe deficiency of leukocyte rolling and recruitment in E-selectin and P-selectin double mutant mice.	SELE SELP	4.97e-06	2	78	2	8642341
Pubmed	Selectins mediate small cell lung cancer systemic metastasis.	SELE SELP	4.97e-06	2	78	2	24699516
Pubmed	Host defense against systemic infection with Streptococcus pneumoniae is impaired in E-, P-, and E-/P-selectin-deficient mice.	SELE SELP	4.97e-06	2	78	2	9329976
Pubmed	Soluble selectin levels in patients with lung cancer.	SELE SELP	4.97e-06	2	78	2	11936588
Pubmed	New discoveries with mice mutant in endothelial and platelet selectins.	SELE SELP	4.97e-06	2	78	2	10605793
Pubmed	Subset-specific reductions in lung lymphocyte accumulation following intratracheal antigen challenge in endothelial selectin-deficient mice.	SELE SELP	4.97e-06	2	78	2	12193727
Pubmed	E- and P-selectin are not required for the development of experimental autoimmune encephalomyelitis in C57BL/6 and SJL mice.	SELE SELP	4.97e-06	2	78	2	18056394
Pubmed	Contrasting effects of P-selectin and E-selectin on the differentiation of murine hematopoietic progenitor cells.	SELE SELP	4.97e-06	2	78	2	15676218
Pubmed	Ser128Arg E-selectin and Thr715Pro P-selectin polymorphisms and severe preeclampsia.	SELE SELP	4.97e-06	2	78	2	17939599
Pubmed	Chromosomal location of fifteen unique mouse KRAB-containing zinc finger loci.	ZNF7 ZNF814 ZNF850 ZNF595	1.11e-05	61	78	4	8662221
Pubmed	Multiple, targeted deficiencies in selectins reveal a predominant role for P-selectin in leukocyte recruitment.	SELE SELP	1.49e-05	3	78	2	10500197
Pubmed	Maspin, E-selectin, and P-selectin expressions in papillary thyroid carcinomas and their correlation with prognostic parameters.	SELE SELP	1.49e-05	3	78	2	18597952
Pubmed	The selectins: vascular adhesion molecules.	SELE SELP	1.49e-05	3	78	2	7542213
Pubmed	Isolated P-selectin glycoprotein ligand-1 dynamic adhesion to P- and E-selectin.	SELE SELP	1.49e-05	3	78	2	9128259
Pubmed	Selectins influence thrombosis in a mouse model of experimental deep venous thrombosis.	SELE SELP	1.49e-05	3	78	2	12505044
Pubmed	The roles of P- and E-selectins and P-selectin glycoprotein ligand-1 in primary and metastatic mouse melanomas.	SELE SELP	1.49e-05	3	78	2	21889879
Pubmed	Quantifying the effects of molecular orientation and length on two-dimensional receptor-ligand binding kinetics.	SELE SELP	1.49e-05	3	78	2	15299021
Pubmed	P-selectin glycoprotein ligand-1 supports rolling on E- and P-selectin in vivo.	SELE SELP	1.49e-05	3	78	2	11071658
Pubmed	P-selectin, and not E-selectin, negatively regulates murine megakaryocytopoiesis.	SELE SELP	1.49e-05	3	78	2	12370396
Pubmed	Selectin Dependence of Allergic Skin Inflammation Is Diminished by Maternal Atopy.	SELE SELP	1.49e-05	3	78	2	34433625
Pubmed	Chronic homocysteine exposure upregulates endothelial adhesion molecules and mediates leukocyte: endothelial cell interactions under flow conditions.	SELE SELP	1.49e-05	3	78	2	21159528
Pubmed	Selectin-mediated recruitment of bone marrow stromal cells in the postischemic cerebral microvasculature.	SELE SELP	1.49e-05	3	78	2	21257828
Pubmed	The genomic landscape and evolution of endometrial carcinoma progression and abdominopelvic metastasis.	PPP2R1A PIK3CA	1.49e-05	3	78	2	27348297
Pubmed	Selectins: a family of adhesion receptors.	SELE SELP	1.49e-05	3	78	2	1717161
Pubmed	Pathophysiologic importance of E- and L-selectin for neutrophil-induced liver injury during endotoxemia in mice.	SELE SELP	1.49e-05	3	78	2	11050049
Pubmed	Lectin adhesion proteins (P-, L- and E-selectins) as biomarkers in colorectal cancer.	SELE SELP	1.49e-05	3	78	2	27775438
Pubmed	Role of primary and secondary capture for leukocyte accumulation in vivo.	SELE SELP	1.49e-05	3	78	2	9440702
Pubmed	L-selectin and E-selectin expressed on monocytes mediating Ehrlichia chaffeensis attachment onto host cells.	SELE SELP	1.49e-05	3	78	2	14592723
Pubmed	Selectin synthesis and inflammation.	SELE SELP	1.49e-05	3	78	2	8851663
Pubmed	Severe inflammatory defect and reduced viability in CD18 and E-selectin double-mutant mice.	SELE SELP	1.49e-05	3	78	2	11120753
Pubmed	Selectins in human amniotic fluid and cord blood plasma. A preliminary report.	SELE SELP	1.49e-05	3	78	2	20580062
Pubmed	A down-regulatable E-selectin ligand is functionally important for PSGL-1-independent leukocyte-endothelial cell interactions.	SELE SELP	1.49e-05	3	78	2	15304396
Pubmed	No detectable endothelial- or leukocyte-derived L-selectin ligand activity on the endothelium in inflamed cremaster muscle venules.	SELE SELP	1.49e-05	3	78	2	18381812
Pubmed	PSGL-1 decorated with sialyl Lewisa/x promotes high affinity binding of myeloma cells to P-selectin but is dispensable for E-selectin engagement.	SELE SELP	1.49e-05	3	78	2	38243063
Pubmed	Hydrocortisone reduced in vivo, inflammation-induced slow rolling of leukocytes and their extravasation into human conjunctiva.	SELE SELP	1.49e-05	3	78	2	12200386
Pubmed	Creation and characterization of E-selectin- and VCAM-1-deficient mice.	SELE SELP	1.49e-05	3	78	2	7587631
Pubmed	Spatiotemporal expression dynamics of selectins govern the sequential extravasation of neutrophils and monocytes in the acute inflammatory response.	SELE SELP	1.49e-05	3	78	2	25722429
Pubmed	Two waves of neutrophil emigration in response to corneal epithelial abrasion: distinct adhesion molecule requirements.	SELE SELP	1.49e-05	3	78	2	16639002
Pubmed	Activation of bone marrow-resident memory T cells by circulating, antigen-bearing dendritic cells.	SELE SELP	1.49e-05	3	78	2	16155571
Pubmed	Age-induced alterations of granulopoiesis generate atypical neutrophils that aggravate stroke pathology.	SELE SELP	1.49e-05	3	78	2	37188941
Pubmed	Higher-affinity oligosaccharide ligands for E-selectin.	SELE SELP	1.49e-05	3	78	2	7680663
Pubmed	Role of selectins in the triggering, growth, and dissemination of T-lymphoma cells: implication of L-selectin in the growth of thymic lymphoma.	SELE SELP	1.49e-05	3	78	2	15705798
Pubmed	E- and p-selectins are essential for repopulation of chronic myelogenous and chronic eosinophilic leukemias in a scid mouse xenograft model.	SELE SELP	1.49e-05	3	78	2	23922938
Pubmed	Overlapping roles of endothelial selectins and vascular cell adhesion molecule-1 in immune complex-induced leukocyte recruitment in the cremasteric microvasculature.	SELE SELP	1.49e-05	3	78	2	14507656
Pubmed	Dermal and pulmonary inflammatory disease in E-selectin and P-selectin double-null mice is reduced in triple-selectin-null mice.	SELE SELP	1.49e-05	3	78	2	11468173
Pubmed	The role of endothelial cell adhesion molecules P-selectin, E-selectin and intercellular adhesion molecule-1 in leucocyte recruitment induced by exogenous methylglyoxal.	SELE SELP	1.49e-05	3	78	2	22681228
Pubmed	Candidate gene analysis of selectin cluster in patients with multiple sclerosis.	SELE SELP	1.49e-05	3	78	2	19240957
Pubmed	P-selectin glycoprotein ligand-1 contributes to wound healing predominantly as a p-selectin ligand and partly as an e-selectin ligand.	SELE SELP	1.49e-05	3	78	2	19177138
Pubmed	Does colorectal cancer clinical advancement affect adhesion molecules (sP-selectin, sE-selectin and ICAM-1) concentration?	SELE SELP	1.49e-05	3	78	2	19136145
Pubmed	β3-Adrenergic receptor stimulation induces E-selectin-mediated adipose tissue inflammation.	SELE SELP	1.49e-05	3	78	2	23235150
Pubmed	Intestinal inflammation in adhesion molecule-deficient mice: an assessment of P-selectin alone and in combination with ICAM-1 or E-selectin.	SELE SELP	1.49e-05	3	78	2	10410991
Pubmed	Cell-cell contact mechanisms.	SELE SELP	1.49e-05	3	78	2	1375831
Pubmed	Effect of extracellular pH on selectin adhesion: theory and experiment.	SELE SELP	1.49e-05	3	78	2	23442851
Pubmed	PSGL-1 and E/P-selectins are essential for T-cell rolling in inflamed CNS microvessels but dispensable for initiation of EAE.	SELE SELP	1.49e-05	3	78	2	24740164
Pubmed	Gene-targeted mice reveal importance of L-selectin-dependent rolling for neutrophil adhesion.	SELE SELP	1.49e-05	3	78	2	9612391
Interaction	LTBP2 interactions	ZNF708 ZNF627 FBN2 ZNF555 ZNF408 RBAK ZNF417 ZNF77	9.59e-10	85	75	8	int:LTBP2
Interaction	TRIM28 interactions	ZNF7 ZNF708 TTF2 ZNF627 ZNF555 VEZF1 ZNF684 ZNF268 ZNF728 ZNF655 ZNF587 RBAK ZNF256 ZNF737 ZNF208 ZNF736 ZNF417 ZNF416 ZNF595 ZNF669 ZNF77 ZNF44 ZNF445	1.86e-09	1474	75	23	int:TRIM28
Interaction	NOTCH2 interactions	ZNF7 ZNF708 ZNF627 FBN2 ZNF555 VEZF1 ZNF408 RBAK ZNF417 ZNF445	3.66e-06	423	75	10	int:NOTCH2
Interaction	VWCE interactions	ZNF627 FBN2 ZNF408 ZNF669 ZNF77	4.01e-06	64	75	5	int:VWCE
Interaction	TRIM41 interactions	ZNF134 ZNF655 ZNF587 ZNF408 RBAK ZNF417 ZNF669	1.94e-05	223	75	7	int:TRIM41
Interaction	TNS2 interactions	ZNF134 PPP2R1A ZNF655 ZNF587 RBAK ZNF417 UTRN	2.71e-05	235	75	7	int:TNS2
Interaction	FBLN5 interactions	ZNF627 ZNF408 ZNF737 UTRN ZNF669 ZNF77	2.82e-05	159	75	6	int:FBLN5
Interaction	SPRED1 interactions	ZNF655 ZNF587 ZNF408 ZNF417	4.86e-05	54	75	4	int:SPRED1
Cytoband	19q13.43	ZNF587 ZNF256 ZNF814 ZNF417 ZNF548	4.12e-07	87	78	5	19q13.43
Cytoband	Ensembl 112 genes in cytogenetic band chr19q13	ZNF134 PPP2R1A ZNF154 ZNF587 ZNF256 ZNF814 ZNF417 ZNF850 ZNF416 ZNF548 ZNF461	5.48e-06	1192	78	11	chr19q13
Cytoband	1q22-q25	SELE SELP	8.54e-06	3	78	2	1q22-q25
Cytoband	19p12	ZNF708 ZNF728 ZNF737 ZNF208	1.76e-05	90	78	4	19p12
Cytoband	Ensembl 112 genes in cytogenetic band chr19p12	ZNF708 ZNF728 ZNF737 ZNF208	5.82e-05	122	78	4	chr19p12
Cytoband	19q13.4	ZNF134 ZNF154 ZNF416	3.40e-04	79	78	3	19q13.4
Cytoband	9q34	ZNF79 DBH	3.85e-03	54	78	2	9q34
Cytoband	1p34.2	ZNF684 CFAP57	4.28e-03	57	78	2	1p34.2
GeneFamily	Zinc fingers C2H2-type\|ZF class homeoboxes and pseudogenes	ZNF7 ZNF708 ZNF134 ZNF627 ZNF716 ZNF555 ZNF154 VEZF1 ZNF684 ZNF268 ZNF728 ZNF655 ZNF587 ZNF408 RBAK ZNF256 ZNF737 ZNF814 ZNF727 ZNF208 ZNF79 ZNF80 ZNF217 ZNF736 ZNF417 ZNF850 ZNF416 ZNF548 ZNF595 ZNF669 ZNF461 ZNF77 ZNF44 ZNF445 ZNF3	3.27e-31	718	68	35	28
GeneFamily	CD molecules\|Selectins\|Sushi domain containing\|C-type lectin domain containing	SELE SELP	4.17e-05	3	68	2	945
Computational	Neighborhood of ZNF198	CELF1 VEZF1 ZNF655 MARCHF6 NLK	5.28e-05	117	38	5	GCM_ZNF198
Computational	Neighborhood of DFFA	CELF1 VEZF1 ZNF655 MARCHF6 C2CD5	8.41e-05	129	38	5	GCM_DFFA
Computational	Neighborhood of SUFU	CELF1 MARCHF6 NLK C2CD5	1.49e-04	77	38	4	GCM_SUFU
Computational	Neighborhood of UBE2N	CELF1 VEZF1 MARCHF6 NLK C2CD5	1.94e-04	154	38	5	GCM_UBE2N
Computational	Neighborhood of MYST2	CELF1 VEZF1 ZNF655 MARCHF6 C2CD5	3.24e-04	172	38	5	GCM_MYST2
Computational	Neighborhood of NCAM1	CELF1 MARCHF6 NLK C2CD5	1.01e-03	127	38	4	GCM_NCAM1
Disease	HEPATOCELLULAR CARCINOMA	IGF2R PIK3CA	2.21e-04	9	74	2	114550
Disease	Hepatocellular carcinoma	IGF2R PIK3CA	2.21e-04	9	74	2	cv:C2239176
Disease	bone density	TTF2 FBN2 CELF1 ZNF408 TAAR9 TNFRSF11A	4.34e-04	388	74	6	EFO_0003923
Disease	Nonsyndromic Deafness	TMEM132E TMPRSS3 TECTA	1.12e-03	81	74	3	C3711374
Disease	hearing impairment	TMPRSS3 TECTA FANCA	1.94e-03	98	74	3	C1384666

Protein segments in the cluster

Peptide	Gene	Start	Entry
FTSRTSACGLFSVCY	PPP2R1A	141	P30153
CCFVTFYTRKAALEA	CELF1	61	Q92879
GYCFSAALSCTFLVS	ALG10B	6	Q5I7T1
GDRFYTFICSVCSSG	MTF2	241	Q9Y483
SKGFCFLCYEDQRST	RBMX2	76	Q9Y388
KITDSTCYSLSRFCS	FBXL2	116	Q9UKC9
CRSYTSFKAGNCFFC	PNLIPRP3	301	Q17RR3
FYSKTKRFCSVSCSR	MBTD1	66	Q05BQ5
FKEYSVRGCGECSFS	CFAP57	466	Q96MR6
CFEVTYLSGSKCFSC	RASAL2	126	Q9UJF2
FTYKSSCAFSCEEGF	SELE	451	P16581
ACRIYKCLFTGSVSS	MARCHF6	111	O60337
KIGSFDETCTRFYTA	PDPK2P	146	Q6A1A2
CCFSTSTGRVYTSDF	NLK	441	Q9UBE8
SGARTSYDEISFCTF	NEU4	441	Q8WWR8
LFTRSCAGYCVATFI	PIK3CA	896	P42336
KFTVSCGCSSEFVFV	ERCC8	296	Q13216
DFKFSSSYSACAAIG	PPP4R3C	771	Q6ZMV5
VYTLAFSCGFCRKED	GYG1	281	P46976
CKLFQFVSESCTYAT	GHSR	116	Q92847
FCTAAISYSLCKFSS	FANCA	836	O15360
ETAFILTGYCTDKCT	DBH	381	P09172
GCSRDSFKVYCNFTA	COL5A1	1661	P20908
LTAFAYGSSCKFECQ	SELP	341	P16109
RKSFCYRSYNGTTCE	FBN2	1736	P35556
SFRCFCKVGYTTDIS	FBN2	2471	P35556
RFRQSSCGVKFFCTT	C2CD5	136	Q86YS7
STSGKRKAFSTCGFY	OR1L8	231	Q8NGR8
YVCAKCGYELFSSRS	MSRB1	21	Q9NZV6
TYYFRVCGKLSSDVC	IGF2R	1256	P11717
YDVCQSCFFSGRTAK	UTRN	3091	P46939
TCRRSVCFTKGYGSY	TRDMT1	286	O14717
SSSCDYVFVSGKESR	TMEM132E	496	Q6IEE7
GDSYCKFHTCFDTSF	TAAR9	101	Q96RI9
CESEGCSKYFTTLSD	MTF1	231	Q14872
MASCRCISGHAFFYT	MEP1A	691	Q16819
GFTYTSSCVLSDRSC	CDC42BPA	401	Q5VT25
FVDSKCCYSSTVAGD	SSUH2	86	Q9Y2M2
VRGCFSTKTSYCLAA	TECTA	1476	O75443
FDCSGKYRCRSSFKC	TMPRSS3	71	P57727
ICEECGKAFTYSSTL	ZNF727	341	A8MUV8
FECKECGKTFRYSSS	ZNF684	271	Q5T5D7
YTCEECGKAFYRSSH	ZNF595	396	Q8IYB9
CGKSFSCYSSFRDHV	ZNF77	301	Q15935
CKECAEAFSYSSTFR	ZNF555	286	Q8NEP9
YECSECGKAFRYSSA	ZNF3	396	P17036
KTSFVCTYCSKAFRD	VEZF1	71	Q14119
FGCSCCEKAFSSKSY	ZNF268	276	Q14587
CSECGKFFSRVSYLT	RBAK	431	Q9NYW8
VCSDCGKSFSRYVSF	ZNF587	241	Q96SQ5
ERSYMCSECGKSFST	ZNF256	236	Q9Y2P7
FLCTECGKSYSSEES	ZNF408	381	Q9H9D4
VCSDCGKSFSRYVSF	ZNF417	241	Q8TAU3
YKCEECGKAFTRSSS	ZNF728	256	P0DKX0
YTCEECGKAFSRSST	ZNF716	296	A6NP11
LYTCEECGKAFTFSS	ZNF716	351	A6NP11
RVFKSGETTYSCRDC	UBR1	101	Q8IWV7
CKQCGKAFSRSTYFR	ZNF627	421	Q7L945
FSFSRGCSYTCAKKI	STAB1	1301	Q9NY15
YKCEECGKAFSVFST	ZNF708	336	P17019
CSECGKTFTYRSVFF	ZNF80	191	P51504
KSYKCSSCERVFSRS	ZNF655	301	Q8N720
CSDCGKDFAYRSAFI	ZNF445	711	P59923
YKCEECGKSFSTFSV	ZNF208	721	O43345
CSECGKFFRQSYTLV	ZNF416	496	Q9BWM5
YECNTCGKFFRYSST	ZNF548	281	Q8NEK5
HLTSSRECSYCGKFF	ZNF217	466	O75362
TTERCYICSECGKSF	ZNF154	156	Q13106
SECGKAFSYCAAFIQ	ZNF79	336	Q15937
SYECQICGKAFSRFS	ZNF44	551	P15621
YSCKECGKSFTSRST	ZNF850	841	A8MQ14
CIECGKFFSRSSDYI	ZNF134	346	P52741
CGECGKSFSKYVSFS	ZNF814	271	B7Z6K7
ECRECGKAFSYHSSF	ZNF461	386	Q8TAF7
YECSECGKAFSRSSY	ZNF7	581	P17097
GKSFYVCRADTCSFV	TTF2	26	Q9UNY4
YECKECGKTFRFSCS	ZNF669	306	Q96BR6
AGYFSDAFSSTDKCR	TNFRSF11A	156	Q9Y6Q6
YICEECGKAFTRSST	ZNF736	341	B4DX44
CEDCGKAFSRFSYLT	ZNF737	231	O75373