Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionchloride:bicarbonate antiporter activity

SLC4A8 SLC4A1 SLC26A6

3.07e-0513973GO:0140900
GeneOntologyMolecularFunctionbicarbonate:monoatomic anion antiporter activity

SLC4A8 SLC4A1 SLC26A6

3.07e-0513973GO:0140829
GeneOntologyMolecularFunctionG protein-coupled amine receptor activity

HTR1D TAAR2 TAAR5 ADRA2B

4.62e-0541974GO:0008227
GeneOntologyMolecularFunctionantiporter activity

SLC4A8 SLC4A1 SLC32A1 SLC30A5 SLC25A2 SLC26A6

5.76e-05138976GO:0015297
GeneOntologyMolecularFunctioncarbonate dehydratase activity

CA13 CA2 CA7

5.94e-0516973GO:0004089
GeneOntologyMolecularFunctiontransmembrane signaling receptor activity

HTR1D TAAR2 KIR2DS2 TAAR5 GABBR2 CD200R1 OR10AG1 ADRA2B GPR174 OR6C2 RXFP2 OR56A3 CCR6 ADGRD2 KIR2DL1 KIR2DL3 KIR2DS5 IL4R

8.04e-0513539718GO:0004888
GeneOntologyMolecularFunctionimmune receptor activity

CD200R1 CCR6 KIR2DL1 KIR2DL3 KIR2DS5 IL4R

1.54e-04165976GO:0140375
GeneOntologyMolecularFunctionbicarbonate transmembrane transporter activity

SLC4A8 SLC4A1 SLC26A6

4.98e-0432973GO:0015106
GeneOntologyMolecularFunctionsolute:inorganic anion antiporter activity

SLC4A8 SLC4A1 SLC26A6

4.98e-0432973GO:0005452
GeneOntologyMolecularFunctionorganic anion transmembrane transporter activity

SLC4A8 SLC4A1 SLC32A1 SLC25A2 SLC33A1 SLC38A6 SLC26A6

5.68e-04293977GO:0008514
GeneOntologyMolecularFunctiontrace-amine receptor activity

TAAR2 TAAR5

6.42e-048972GO:0001594
GeneOntologyMolecularFunctionorganic cation transmembrane transporter activity

SLC32A1 SLC22A16 SLC25A2 SLC38A6

7.17e-0483974GO:0015101
GeneOntologyMolecularFunctionG protein-coupled receptor activity

HTR1D TAAR2 TAAR5 GABBR2 OR10AG1 ADRA2B GPR174 OR6C2 RXFP2 OR56A3 CCR6 ADGRD2

1.18e-038849712GO:0004930
GeneOntologyBiologicalProcessregulation of dipeptide transport

SLC26A6 CA2

2.23e-052982GO:0090089
GeneOntologyBiologicalProcessregulation of oligopeptide transport

SLC26A6 CA2

2.23e-052982GO:0090088
GeneOntologyBiologicalProcesspositive regulation of dipeptide transport

SLC26A6 CA2

2.23e-052982GO:2000880
GeneOntologyBiologicalProcesspositive regulation of oligopeptide transport

SLC26A6 CA2

2.23e-052982GO:2000878
GeneOntologyBiologicalProcesspositive regulation of dipeptide transmembrane transport

SLC26A6 CA2

2.23e-052982GO:2001150
GeneOntologyBiologicalProcessregulation of dipeptide transmembrane transport

SLC26A6 CA2

2.23e-052982GO:2001148
GeneOntologyBiologicalProcessregulation of intracellular pH

SLC4A8 SLC4A1 SLC26A6 CA2 CA7

8.58e-0594985GO:0051453
GeneOntologyBiologicalProcessregulation of cellular pH

SLC4A8 SLC4A1 SLC26A6 CA2 CA7

1.21e-04101985GO:0030641
GeneOntologyBiologicalProcessangiotensin-activated signaling pathway

CAV1 SLC26A6 CA2

1.96e-0424983GO:0038166
GeneOntologyBiologicalProcesscellular response to hyperoxia

ATG7 CAV1

2.21e-045982GO:0071455
GeneOntologyBiologicalProcesspositive regulation of cellular pH reduction

CA2 CA7

2.21e-045982GO:0032849
GeneOntologyBiologicalProcessregulation of pH

SLC4A8 SLC4A1 SLC26A6 CA2 CA7

2.70e-04120985GO:0006885
GeneOntologyCellularComponentcaveolar macromolecular signaling complex

CACNA1C CAV1 CAV2

9.69e-083973GO:0002095
GeneOntologyCellularComponentintegrator complex

INTS13 INTS15 INTS11

1.21e-0421973GO:0032039
GeneOntologyCellularComponentbasal part of cell

SLC4A8 CAV1 SLC4A1 DST CLRN1 SLC26A6 CDH16 CA2

3.78e-04378978GO:0045178
HumanPhenoHypocalcemia

CACNA1C CAV1 SLC4A1 HIRA FOCAD CA2

6.76e-0686296HP:0002901
DomainCA2

CA13 CA2

2.61e-052962IPR018443
DomainCarbonic_anhydrase_a-class_CS

CA13 CA2 CA7

2.80e-0512963IPR018338
DomainCarbonic_anhydrase_a-class

CA13 CA2 CA7

5.73e-0515963IPR023561
DomainALPHA_CA_1

CA13 CA2 CA7

5.73e-0515963PS00162
DomainCaveolin

CAV1 CAV2

7.82e-053962IPR001612
DomainCaveolin_CS

CAV1 CAV2

7.82e-053962IPR018361
Domain-

RASA4 RASA4B

7.82e-0539624.10.1130.10
DomainCaveolin

CAV1 CAV2

7.82e-053962PF01146
DomainCAVEOLIN

CAV1 CAV2

7.82e-053962PS01210
DomainALPHA_CA_2

CA13 CA2 CA7

8.49e-0517963PS51144
DomainCarb_anhydrase

CA13 CA2 CA7

8.49e-0517963PF00194
DomainCarb_anhydrase

CA13 CA2 CA7

8.49e-0517963SM01057
Domain-

CA13 CA2 CA7

8.49e-05179633.10.200.10
DomainCarbonic_anhydrase_a

CA13 CA2 CA7

8.49e-0517963IPR001148
DomainTAAR_fam

TAAR2 TAAR5

5.40e-047962IPR009132
DomainANION_EXCHANGER_2

SLC4A8 SLC4A1

5.40e-047962PS00220
DomainANION_EXCHANGER_1

SLC4A8 SLC4A1

5.40e-047962PS00219
DomainBTK

RASA4 RASA4B

9.19e-049962SM00107
DomainZnf_Btk_motif

RASA4 RASA4B

9.19e-049962IPR001562
DomainBand3_cytoplasmic_dom

SLC4A8 SLC4A1

9.19e-049962IPR013769
DomainBand_3_cyto

SLC4A8 SLC4A1

9.19e-049962PF07565
Domain-

SLC4A8 SLC4A1

9.19e-0499623.40.1100.10
DomainBTK

RASA4 RASA4B

9.19e-049962PF00779
DomainZF_BTK

RASA4 RASA4B

9.19e-049962PS51113
DomainIG_LIKE

KIR2DS2 IGFBPL1 CD200R1 HEPACAM CD86 BTN2A3P KIR2DL1 KIR2DL3 KIR2DS5

9.54e-04491969PS50835
DomainIg-like_dom

KIR2DS2 IGFBPL1 CD200R1 HEPACAM CD86 BTN2A3P KIR2DL1 KIR2DL3 KIR2DS5

1.13e-03503969IPR007110
DomainHCO3_cotransp

SLC4A8 SLC4A1

1.15e-0310962PF00955
DomainHCO3_transpt_C

SLC4A8 SLC4A1

1.15e-0310962IPR011531
DomainPTrfase/Anion_transptr

SLC4A8 SLC4A1

1.15e-0310962IPR016152
DomainHCO3_transpt_euk

SLC4A8 SLC4A1

1.15e-0310962IPR003020
DomainIG

KIR2DS2 IGFBPL1 CD200R1 HEPACAM CD86 KIR2DL1 KIR2DL3 KIR2DS5

1.47e-03421968SM00409
DomainIg_sub

KIR2DS2 IGFBPL1 CD200R1 HEPACAM CD86 KIR2DL1 KIR2DL3 KIR2DS5

1.47e-03421968IPR003599
DomainRasGAP

RASA4 RASA4B

2.29e-0314962SM00323
DomainRasGAP_CS

RASA4 RASA4B

2.29e-0314962IPR023152
DomainGPCR_Rhodpsn_7TM

HTR1D TAAR2 TAAR5 OR10AG1 ADRA2B GPR174 OR6C2 RXFP2 OR56A3 CCR6

2.32e-036709610IPR017452
Domain7tm_1

HTR1D TAAR2 TAAR5 OR10AG1 ADRA2B GPR174 OR6C2 RXFP2 OR56A3 CCR6

2.50e-036779610PF00001
DomainRasGAP

RASA4 RASA4B

2.63e-0315962PF00616
DomainRAS_GTPASE_ACTIV_1

RASA4 RASA4B

2.63e-0315962PS00509
DomainRAS_GTPASE_ACTIV_2

RASA4 RASA4B

2.63e-0315962PS50018
Domain7TM_GPCR_Srsx

HTR1D TAAR2 TAAR5 ADRA2B

2.66e-03112964SM01381
DomainG_PROTEIN_RECEP_F1_1

HTR1D TAAR2 TAAR5 OR10AG1 ADRA2B GPR174 OR6C2 RXFP2 OR56A3 CCR6

2.72e-036859610PS00237
DomainG_PROTEIN_RECEP_F1_2

HTR1D TAAR2 TAAR5 OR10AG1 ADRA2B GPR174 OR6C2 RXFP2 OR56A3 CCR6

2.90e-036919610PS50262
DomainGPCR_Rhodpsn

HTR1D TAAR2 TAAR5 OR10AG1 ADRA2B GPR174 OR6C2 RXFP2 OR56A3 CCR6

2.93e-036929610IPR000276
Domain-

RASA4 RASA4B

2.99e-03169621.10.506.10
DomainIg-like_fold

KIR2DS2 IGFBPL1 CD200R1 HEPACAM CD86 BTN2A3P KIR2DL1 KIR2DL3 KIR2DS5 IL4R

3.38e-037069610IPR013783
DomainAa_trans

SLC32A1 SLC38A6

3.38e-0317962PF01490
DomainAA_transpt_TM

SLC32A1 SLC38A6

3.38e-0317962IPR013057
DomainRasGAP_dom

RASA4 RASA4B

3.79e-0318962IPR001936
PathwayREACTOME_REVERSIBLE_HYDRATION_OF_CARBON_DIOXIDE

CA13 CA2 CA7

2.39e-0512693M671
PathwayREACTOME_REVERSIBLE_HYDRATION_OF_CARBON_DIOXIDE

CA13 CA2 CA7

2.39e-0512693MM14574
PathwayREACTOME_AMINE_LIGAND_BINDING_RECEPTORS

HTR1D TAAR2 TAAR5 ADRA2B

5.11e-0542694M5868
PathwayREACTOME_AMINE_LIGAND_BINDING_RECEPTORS

HTR1D TAAR2 TAAR5 ADRA2B

5.11e-0542694MM14971
PathwayREACTOME_SLC_MEDIATED_TRANSMEMBRANE_TRANSPORT

SLC4A8 SLC4A1 SLC32A1 SLC30A5 SLC22A16 SLC33A1 SLC26A6

1.59e-04238697MM15076
PathwayKEGG_NITROGEN_METABOLISM

CA13 CA2 CA7

1.85e-0423693M4629
PathwayREACTOME_SLC_MEDIATED_TRANSMEMBRANE_TRANSPORT

SLC4A8 SLC4A1 SLC32A1 SLC30A5 SLC22A16 SLC33A1 SLC26A6

2.09e-04249697M5988
Pubmed

NullHap--a versatile application to estimate haplotype frequencies from unphased genotypes in the presence of null alleles.

KIR2DS2 KIR2DL1 KIR2DL3 KIR2DS5

4.29e-09899418681957
Pubmed

Molecular clones of the p58 NK cell receptor reveal immunoglobulin-related molecules with diversity in both the extra- and intracellular domains.

KIR2DS2 KIR2DL1 KIR2DL3 KIR2DS5

7.70e-0999947749980
Pubmed

Assessment of killer cell immunoglobulinlike receptor expression and corresponding HLA class I phenotypes demonstrates heterogenous KIR expression independent of anticipated HLA class I ligands.

KIR2DS2 KIR2DL1 KIR2DL3 KIR2DS5

1.28e-081099412559621
Pubmed

Natural killer cells and immune surveillance.

KIR2DS2 KIR2DL1 KIR2DL3 KIR2DS5

2.01e-081199418830515
Pubmed

[Genotype analysis of killer cell immunoglobulin-like receptors in Graves' disease patients].

KIR2DS2 KIR2DL1 KIR2DL3 KIR2DS5

2.01e-081199419664392
Pubmed

Association of killer cell immunoglobulin-like receptor 2DL5 with systemic lupus erythematosus and accompanying infections.

KIR2DS2 KIR2DL1 KIR2DL3 KIR2DS5

3.00e-081299420371502
Pubmed

Association of killer cell immunoglobulin-like receptors with primary Sjogren's syndrome.

KIR2DS2 KIR2DL1 KIR2DL3 KIR2DS5

3.00e-081299419181658
Pubmed

[Polymorphism of killer cell immunoglobulin-like receptor gene and its correlation with leukemia].

KIR2DS2 KIR2DL1 KIR2DL3 KIR2DS5

3.00e-081299417490516
Pubmed

[Relationship between CMV reactivation and KIR haplotype/HLA-Cw genotype in patients after unrelated-donor hematopoietic stem cell transplantation.].

KIR2DS2 KIR2DL1 KIR2DL3 KIR2DS5

3.00e-081299420137308
Pubmed

Distribution of killer cell immunoglobulin-like receptors (KIR) and their HLA-C ligands in two Iranian populations.

KIR2DS2 KIR2DL1 KIR2DL3 KIR2DS5

3.00e-081299419936734
Pubmed

[Study on the polymorphism of killer cell immunoglobulin like receptor (KIR) gene with systemic lupus erythematosus of North population in China].

KIR2DS2 KIR2DL1 KIR2DL3 KIR2DS5

4.33e-081399418687225
Pubmed

KIR and HLA genotypes are associated with disease progression and survival following autologous hematopoietic stem cell transplantation for high-risk neuroblastoma.

KIR2DS2 KIR2DL1 KIR2DL3 KIR2DS5

4.33e-081399419934297
Pubmed

Different KIRs confer susceptibility and protection to adults with latent autoimmune diabetes in Latvian and Asian Indian populations.

KIR2DS2 KIR2DL1 KIR2DL3 KIR2DS5

4.33e-081399419120281
Pubmed

Role of human leukocyte antigen, killer-cell immunoglobulin-like receptors, and cytokine gene polymorphisms in leptospirosis.

KIR2DS2 KIR2DL1 KIR2DL3 KIR2DS5 IL4R

5.12e-083599519683555
Pubmed

Frequencies of killer immunoglobulin-like receptor genotypes influence susceptibility to spontaneous abortion.

KIR2DS2 KIR2DL1 KIR2DL3 KIR2DS5

6.05e-081499419875891
Pubmed

Multiple sclerosis associates with LILRA3 deletion in Spanish patients.

KIR2DS2 KIR2DL1 KIR2DL3 KIR2DS5

6.05e-081499419421224
Pubmed

Distribution of killer cell immunoglobulin-like receptor genes in the Chinese Han population.

KIR2DS2 KIR2DL1 KIR2DL3 KIR2DS5

6.05e-081499415896204
Pubmed

Killer cell immunoglobulin-like receptor gene diversity in a Caucasian population of southern Brazil.

KIR2DS2 KIR2DL1 KIR2DL3 KIR2DS5

8.23e-081599420082646
Pubmed

Disparate distribution of activating and inhibitory killer cell immunoglobulin-like receptor genes in patients with systemic lupus erythematosus.

KIR2DS2 KIR2DL1 KIR2DL3 KIR2DS5

8.23e-081599419926642
Pubmed

Killer cell immunoglobulin-like receptors in HLA-B27-associated acute anterior uveitis, with and without axial spondyloarthropathy.

KIR2DS2 KIR2DL1 KIR2DL3 KIR2DS5

8.23e-081599419850842
Pubmed

Natural killer-cell receptor polymorphisms and posttransplantation non-Hodgkin lymphoma.

KIR2DS2 KIR2DL1 KIR2DL3 KIR2DS5

8.23e-081599420207982
Pubmed

Killer immunoglobulin-like receptors (KIR2DL2 and/or KIR2DS2) in presence of their ligand (HLA-C1 group) protect against chronic myeloid leukaemia.

KIR2DS2 KIR2DL1 KIR2DL3 KIR2DS5

8.23e-081599419493232
Pubmed

[Killer cell immunoglobin-like receptor and its ligand gene polymorphisms in Hunan Han patients with type 1 diabetes].

KIR2DS2 KIR2DL1 KIR2DL3 KIR2DS5

8.23e-081599420356536
Pubmed

Inhibitory KIR and specific HLA-C gene combinations confer susceptibility to or protection against chronic hepatitis B.

KIR2DS2 KIR2DL1 KIR2DL3 KIR2DS5

8.23e-081599420643584
Pubmed

KIR genes polymorphism in Argentinean Caucasoid and Amerindian populations.

KIR2DS2 KIR2DL1 KIR2DL3 KIR2DS5

8.23e-081599417498266
Pubmed

Killer cell immunoglobulin-like receptor genotype and killer cell immunoglobulin-like receptor-human leukocyte antigen C ligand compatibility affect the severity of hepatitis C virus recurrence after liver transplantation.

KIR2DS2 KIR2DL1 KIR2DL3 KIR2DS5

8.23e-081599419326408
Pubmed

Killer cell immunoglobulin-like receptor gene-cluster 3DS1-2DL5-2DS1-2DS5 predisposes susceptibility to Vogt-Koyanagi-Harada syndrome in Japanese individuals.

KIR2DS2 KIR2DL1 KIR2DL3 KIR2DS5

1.09e-071699419897003
Pubmed

Diversity of killer cell immunoglobulin-like receptor genes in Indonesian populations of Java, Kalimantan, Timor and Irian Jaya.

KIR2DS2 KIR2DL1 KIR2DL3 KIR2DS5

1.09e-071699419000141
Pubmed

Diversity of killer cell immunoglobulin-like receptor genes in Indonesian populations of Sumatra, Sulawesi and Moluccas Islands.

KIR2DS2 KIR2DL1 KIR2DL3 KIR2DS5

1.09e-071699420670355
Pubmed

Activating killer cell immunoglobulin-like receptor genes' association with recurrent miscarriage.

KIR2DS2 KIR2DL1 KIR2DL3 KIR2DS5

1.09e-071699419527230
Pubmed

Polymorphisms of KIR gene and HLA-C alleles: possible association with susceptibility to HLA-B27-positive patients with ankylosing spondylitis.

KIR2DS2 KIR2DL1 KIR2DL3 KIR2DS5

1.09e-071699420652381
Pubmed

Asian population frequencies and haplotype distribution of killer cell immunoglobulin-like receptor (KIR) genes among Chinese, Malay, and Indian in Singapore.

KIR2DS2 KIR2DL1 KIR2DL3 KIR2DS5

1.09e-071699418668235
Pubmed

Influence of activating and inhibitory killer immunoglobulin-like receptors on predisposition to recurrent miscarriages.

KIR2DS2 KIR2DL1 KIR2DL3 KIR2DS5

1.09e-071699419279038
Pubmed

No association of KIR genes with Behcet's disease.

KIR2DS2 KIR2DL1 KIR2DL3 KIR2DS5

1.09e-071699417868255
Pubmed

A study of the killer cell immunoglobulin-like receptor gene KIR2DS1 in a Caucasoid Brazilian population with psoriasis vulgaris.

KIR2DS2 KIR2DL1 KIR2DL3 KIR2DS5

1.09e-071699418643961
Pubmed

Distribution of killer cell immunoglobulin-like receptor (KIR) genotypes in patients with familial Mediterranean fever.

KIR2DS2 KIR2DL1 KIR2DL3 KIR2DS5

1.09e-071699419309280
Pubmed

Report from the killer immunoglobulin-like receptor (KIR) anthropology component of the 15th International Histocompatibility Workshop: worldwide variation in the KIR loci and further evidence for the co-evolution of KIR and HLA.

KIR2DS2 KIR2DL1 KIR2DL3 KIR2DS5

1.09e-071699420331834
Pubmed

[Polymorphism of killer cell immunoglobulin-like receptors gene family in Zhejiang Han population].

KIR2DS2 KIR2DL1 KIR2DL3 KIR2DS5

1.09e-071699416403292
Pubmed

HLA-DQA1*0505 sharing and killer immunoglobulin-like receptors in sub fertile couples: report from the 15th International Histocompatibility Workshop.

KIR2DS2 KIR2DL1 KIR2DL3 KIR2DS5

1.09e-071699420210919
Pubmed

The beneficial impact of missing KIR ligands and absence of donor KIR2DS3 gene on outcome following unrelated hematopoietic SCT for myeloid leukemia in the Chinese population.

KIR2DS2 KIR2DL1 KIR2DL3 KIR2DS5

1.43e-071799420173784
Pubmed

The role of killer immunoglobulin-like receptor haplotypes on the outcome of unrelated donor haematopoietic SCT for thalassaemia.

KIR2DS2 KIR2DL1 KIR2DL3 KIR2DS5

1.43e-071799420173792
Pubmed

Role of killer cell immunoglobulin-like receptor gene content and human leukocyte antigen-C group in susceptibility to human T-lymphotropic virus 1-associated myelopathy/tropical spastic paraparesis in Peru.

KIR2DS2 KIR2DL1 KIR2DL3 KIR2DS5

1.43e-071799420483367
Pubmed

[Effects of killer immunoglobulin-like receptor and human leukocyte antigen class I ligand on the prognosis of related donor hematopoietic stem cell transplantation].

KIR2DS2 KIR2DL1 KIR2DL3 KIR2DS5

1.43e-071799419968064
Pubmed

[Analysis of natural killer cell immunoglobulin-like receptor genes in Chinese].

KIR2DS2 KIR2DL1 KIR2DL3 KIR2DS5

1.43e-071799419218127
Pubmed

KIR genes and KIR ligands affect occurrence of acute GVHD after unrelated, 12/12 HLA matched, hematopoietic stem cell transplantation.

KIR2DS2 KIR2DL1 KIR2DL3 KIR2DS5

1.43e-071799419169284
Pubmed

Association of KIR2DS1 and KIR2DS3 with fatal outcome in Ebola virus infection.

KIR2DS2 KIR2DL1 KIR2DL3 KIR2DS5

1.43e-071799420878400
Pubmed

Killer cell immunoglobulin-like receptor gene diversity in the Tibetan ethnic minority group of China.

KIR2DS2 KIR2DL1 KIR2DL3 KIR2DS5

1.43e-071799420650299
Pubmed

Killer cell immunoglobulin-like receptor gene polymorphisms in patients with leukemia: possible association with susceptibility to the disease.

KIR2DS2 KIR2DL1 KIR2DL3 KIR2DS5

1.43e-071799419450876
Pubmed

Distribution of killer-cell immunoglobulin-like receptor genes in Eastern mainland Chinese Han and Taiwanese Han populations.

KIR2DS2 KIR2DL1 KIR2DL3 KIR2DS5

1.43e-071799419761533
Pubmed

Killer immunoglobulin-like receptor ligand HLA-Bw4 protects against multiple sclerosis.

KIR2DS2 KIR2DL1 KIR2DL3 KIR2DS5

1.83e-071899419630074
Pubmed

Influence of HLA class I and HLA-KIR compound genotypes on HIV-2 infection and markers of disease progression in a Manjako community in West Africa.

KIR2DS2 KIR2DL1 KIR2DL3 KIR2DS5

1.83e-071899420519398
Pubmed

Signatures of natural selection and coevolution between killer cell immunoglobulin-like receptors (KIR) and HLA class I genes.

KIR2DS2 KIR2DL1 KIR2DL3 KIR2DS5

1.83e-071899420200544
Pubmed

Combination of KIR 2DL2 and HLA-C1 (Asn 80) confers susceptibility to type 1 diabetes in Latvians.

KIR2DS2 KIR2DL1 KIR2DL3 KIR2DS5

1.83e-071899419046302
Pubmed

Effect of killer immunoglobulin-like receptors in the response to combined treatment in patients with chronic hepatitis C virus infection.

KIR2DS2 KIR2DL1 KIR2DL3 KIR2DS5

1.83e-071899419846535
Pubmed

Association of killer cell immunoglobulin-like receptors and human leukocyte antigen-C genotypes in South Brazilian with type 1 diabetes.

KIR2DS2 KIR2DL1 KIR2DL3 KIR2DS5

1.83e-071899420580654
Pubmed

Distribution of killer cell immunoglobulin-like receptor genes in the mestizo population from Venezuela.

KIR2DS2 KIR2DL1 KIR2DL3 KIR2DS5

1.83e-071899420210918
Pubmed

Activating killer cell immunoglobulin-like receptor gene KIR2DS1 is associated with psoriatic arthritis.

KIR2DS2 KIR2DL1 KIR2DL3

2.23e-07599316112031
Pubmed

Cloning of immunoglobulin-superfamily members associated with HLA-C and HLA-B recognition by human natural killer cells.

KIR2DS2 KIR2DL1 KIR2DL3

2.23e-0759937716543
Pubmed

Association of killer cell immunoglobulin-like receptor genotypes with vascular arterial events and anticardiolipin antibodies in patients with lupus.

KIR2DS2 KIR2DL1 KIR2DL3

2.23e-07599318755860
Pubmed

Diversity of the repertoire of p58 killer cell inhibitory receptors in a single individual.

KIR2DS2 KIR2DL1 KIR2DL3

2.23e-07599310424431
Pubmed

KIR and HLA gene combinations in Vogt-Koyanagi-Harada disease.

KIR2DS2 KIR2DL1 KIR2DL3 KIR2DS5

2.32e-071999418571006
Pubmed

Association between killer-cell immunoglobulin-like receptor genotypes and leprosy in Brazil.

KIR2DS2 KIR2DL1 KIR2DL3 KIR2DS5

2.32e-071999418778326
Pubmed

Associations between genes for killer immunoglobulin-like receptors and their ligands in patients with solid tumors.

KIR2DS2 KIR2DL1 KIR2DL3 KIR2DS5

2.32e-071999420600442
Pubmed

Killer cell immunoglobulin-like receptor gene diversity in a Southern Brazilian population from the state of ParanĂ¡.

KIR2DS2 KIR2DL1 KIR2DL3 KIR2DS5

2.32e-071999418848853
Pubmed

Compound KIR-HLA genotype analyses in the Iranian population by a novel PCR-SSP assay.

KIR2DS2 KIR2DL1 KIR2DL3 KIR2DS5

2.89e-072099420193031
Pubmed

Activating killer cell immunoglobulin-like receptors 3DS1 and 2DS1 protect against developing the severe form of recurrent respiratory papillomatosis.

KIR2DS2 KIR2DL1 KIR2DL3 KIR2DS5

3.56e-072199419861144
Pubmed

Distribution of KIR genes in the population of unrelated individuals homozygous for ancestral haplotype AH8.1 (HLA-A1B8DR3).

KIR2DS2 KIR2DL1 KIR2DL3 KIR2DS5

4.34e-072299420492596
Pubmed

Activation of a subset of human NK cells upon contact with Plasmodium falciparum-infected erythrocytes.

KIR2DS2 KIR2DL1 KIR2DS5

7.77e-07799314607943
Pubmed

Identification of seventeen novel KIR variants: fourteen of them from two non-Caucasian donors.

KIR2DS2 KIR2DL1 KIR2DL3

7.77e-07799311169255
Pubmed

Carbonic anhydrases in the mouse harderian gland.

CA13 CA2 CA7

1.24e-06899320820888
Pubmed

Immunogenetic characteristics of patients with autoimmune gastritis.

KIR2DS2 KIR2DL1 KIR2DL3 KIR2DS5

1.39e-062999420082482
Pubmed

Alternatively spliced forms of human killer inhibitory receptors.

KIR2DS2 KIR2DL3 KIR2DS5

1.86e-0699938662091
Pubmed

Multilevel proteomics reveals host perturbations by SARS-CoV-2 and SARS-CoV.

LEMD3 LPCAT4 IDH1 CAV1 CAV2 FOCAD SLC30A5 XPO5 SLC25A2 MACO1 FURIN HERC1 SLC33A1 CDH16

1.90e-061061991433845483
Pubmed

A systematic quantification of carbonic anhydrase transcripts in the mouse digestive system.

CA13 CA2 CA7

4.83e-061299317362527
Pubmed

Genome-wide analysis of multi-ancestry cohorts identifies new loci influencing intraocular pressure and susceptibility to glaucoma.

ABO CAV1 CAV2

4.83e-061299325173106
Pubmed

[Genotype and haplotype analysis of killer cell immunoglobulin-like receptors in ankylosing spondylitis].

KIR2DS2 KIR2DL1 KIR2DL3

7.96e-061499319489269
Pubmed

Donors with group B KIR haplotypes improve relapse-free survival after unrelated hematopoietic cell transplantation for acute myelogenous leukemia.

KIR2DS2 KIR2DL1 KIR2DS5

7.96e-061499318945962
Pubmed

Cell-type and tissue-specific expression of caveolin-2. Caveolins 1 and 2 co-localize and form a stable hetero-oligomeric complex in vivo.

CAV1 CAV2

8.02e-0629929361015
Pubmed

Neuronal carbonic anhydrase VII provides GABAergic excitatory drive to exacerbate febrile seizures.

CA2 CA7

8.02e-06299223881097
Pubmed

Association of the CAV1-CAV2 locus with normal-tension glaucoma in Chinese and Japanese.

CAV1 CAV2

8.02e-06299232162426
Pubmed

High expressions of caveolins on the proliferating bile ductules in primary biliary cirrhosis.

CAV1 CAV2

8.02e-06299215968725
Pubmed

Caveolin-1 and caveolin-2 expression in mouse macrophages. High density lipoprotein 3-stimulated secretion and a lack of significant subcellular co-localization.

CAV1 CAV2

8.02e-06299211316799
Pubmed

Hepatic overexpression of caveolins increases bile salt secretion in mice.

CAV1 CAV2

8.02e-06299214647059
Pubmed

Localization of the Cl-/HCO3- anion exchanger binding site to the amino-terminal region of carbonic anhydrase II.

SLC4A1 CA2

8.02e-06299211063570
Pubmed

Association study of genetic variants on chromosome 7q31 with susceptibility to normal tension glaucoma in a Japanese population.

CAV1 CAV2

8.02e-06299223743525
Pubmed

Genes encoding human caveolin-1 and -2 are co-localized to the D7S522 locus (7q31.1), a known fragile site (FRA7G) that is frequently deleted in human cancers.

CAV1 CAV2

8.02e-0629929801158
Pubmed

Association of single-nucleotide polymorphism rs4236601 near caveolin 1 and 2 with primary open-angle glaucoma: a meta-analysis.

CAV1 CAV2

8.02e-06299224034151
Pubmed

Expression of KIR2DL3 and KIR2DS2 natural killer receptors in exercise.

KIR2DS2 KIR2DL3

8.02e-06299221165439
Pubmed

The presence of KIR2DS5 confers protection against adult immune thrombocytopenia.

KIR2DS2 KIR2DS5

8.02e-06299224571473
Pubmed

Sequence and detailed organization of the human caveolin-1 and -2 genes located near the D7S522 locus (7q31.1). Methylation of a CpG island in the 5' promoter region of the caveolin-1 gene in human breast cancer cell lines.

CAV1 CAV2

8.02e-06299210218480
Pubmed

CAPRI regulates Ca(2+)-dependent inactivation of the Ras-MAPK pathway.

RASA4 RASA4B

8.02e-06299211448776
Pubmed

Stromal Caveolin-1 and Caveolin-2 Expression in Primary Tumors and Lymph Node Metastases.

CAV1 CAV2

8.02e-06299229850392
Pubmed

The scaffolding domain of caveolin 2 is responsible for its Golgi localization in Caco-2 cells.

CAV1 CAV2

8.02e-06299212414992
Pubmed

Caveolin-1 and -2 in airway epithelium: expression and in situ association as detected by FRET-CLSM.

CAV1 CAV2

8.02e-06299216904002
Pubmed

Donor killer immunoglobulin-like receptor (KIR) genotype-patient cognate KIR ligand combination and antithymocyte globulin preadministration are critical factors in outcome of HLA-C-KIR ligand-mismatched T cell-replete unrelated bone marrow transplantation.

KIR2DS2 KIR2DL3

8.02e-06299218158964
Pubmed

An intramolecular transport metabolon: fusion of carbonic anhydrase II to the COOH terminus of the Cl(-)/HCO(3)(-)exchanger, AE1.

SLC4A1 CA2

8.02e-06299221543742
Pubmed

The overexpression of caveolin-1 and caveolin-2 correlates with a poor prognosis and tumor progression in esophageal squamous cell carcinoma.

CAV1 CAV2

8.02e-06299217671707
Pubmed

Caveolin-1 null mice develop cardiac hypertrophy with hyperactivation of p42/44 MAP kinase in cardiac fibroblasts.

CAV1 CAV2

8.02e-06299212388077
Pubmed

The sequence of human caveolin reveals identity with VIP21, a component of transport vesicles.

CAV1 CAV2

8.02e-0629921360410
Pubmed

Chromosome 7q31 POAG locus: ocular expression of caveolins and lack of association with POAG in a US cohort.

CAV1 CAV2

8.02e-06299221321670
InteractionKIR3DP1 interactions

KIR2DS2 KIR2DL1 KIR2DS5

3.32e-074893int:KIR3DP1
Cytoband19q13.4

KIR2DS2 KIR2DL1 KIR2DL3 KIR2DS5

2.70e-057999419q13.4
GeneFamilyCD molecules|Killer cell immunoglobulin like receptors

KIR2DS2 KIR2DL1 KIR2DL3 KIR2DS5

8.00e-0718754620
GeneFamilySolute carriers

SLC4A8 SLC4A1 SLC32A1 SLC30A5 SLC22A16 SLC25A2 SLC33A1 SLC38A6 SLC26A6 SLC22A31

5.17e-063957510752
GeneFamilyCarbonic anhydrases

CA13 CA2 CA7

5.35e-0518753460
GeneFamilyADAM metallopeptidase domain containing|CD molecules

KIR2DS2 SLC4A1 CD86 CCR6 KIR2DL1 KIR2DL3 KIR2DS5 IL4R

2.24e-04394758471
GeneFamilyTrace amine receptors

TAAR2 TAAR5

6.00e-049752188
GeneFamilyPleckstrin homology domain containing|SH2 domain containing|C2 and RasGAP domain containing

RASA4 RASA4B

7.48e-0410752830
GeneFamilyUbiquitin specific peptidases

USP45 USP9Y PAN2

1.62e-0356753366
GeneFamilyIntegrator complex

INTS13 INTS11

1.72e-03157521366
CoexpressionNOUSHMEHR_GBM_SOMATIC_MUTATED

LEMD3 IDH1 DST

3.81e-069953M2089
ToppCellfacs-Pancreas-Exocrine-3m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CACNA1C GABBR2 HEATR6 DST PAXIP1 HERC1

2.29e-06178956fcbbcc44271515de1969b4732b6441c012693d5f
ToppCell368C-Epithelial_cells-Epithelial-E_(AT2)|368C / Donor, Lineage, Cell class and subclass (all cells)

ABO DRAM1 BSPRY TMC5 CA2 SLC22A31

3.23e-061899566f2322d017b74a1757c81d6e06f50ead8c3dd0cc
ToppCell368C-Epithelial_cells-Epithelial-E_(AT2)-|368C / Donor, Lineage, Cell class and subclass (all cells)

ABO DRAM1 BSPRY TMC5 CA2 SLC22A31

3.23e-06189956926b5fa3064b501a57ba78583e8af33532add455
ToppCellNeuronal|World / cells hierarchy compared to all cells using T-Statistic

CACNA1C GABBR2 TENM2 FOCAD HERC1 NRG3

4.48e-0620095648d801219bc771d6c7e151dc88ca4c179988de85
ToppCell368C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_6|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

SLC4A8 CAV2 TUBGCP5 KIR2DL1 KIR2DL3

1.99e-05154955ba55a63cfa5e0fb9dfec794f80078a2f0d03d0ad
ToppCellCOVID-19-lung-RBC|COVID-19 / Disease (COVID-19 only), tissue and cell type

SLC4A1 SLC22A16 MACO1 HERC1 CA2

3.67e-051759554c35292ad2ac712ba7516f27dd6eac6ba8fdd163
ToppCellAdult-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)-D122|Adult / Lineage, Cell type, age group and donor

ABO USP9Y OR6C2 XKRX SLC22A31

3.77e-051769553fee8a367bb9755aca1b7fcc968b08e51b6e9436
ToppCellChildren_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_1-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

CAV1 CAV2 ARHGEF4 NRG3 TMC5

4.09e-051799554f6ca313b78aa93557937a046c44dcf8bcc9963c
ToppCelldroplet-Lung-nan-21m-Myeloid-Ccr7+_Dendritic|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC4A8 CA13 PPEF2 CD86 ARHGEF4

4.09e-05179955d78eacf47847a50888dd16c35bed9b7afc80010f
ToppCellChildren_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_1|Children_(3_yrs) / Lineage, Cell type, age group and donor

CAV1 CAV2 DST NRG3 TMC5

4.78e-051859551c222f7285d6e3dae0354dc7e853ddc0ea55e63e
ToppCellAdult-Epithelial-alveolar_epithelial_cell_type_1-D175|Adult / Lineage, Cell type, age group and donor

CAV1 CAV2 DST NRG3 TMC5

4.78e-0518595532b4e68e551d435a732f253f6ad83408c759a642
ToppCelldroplet-Pancreas-Exocrine-24m-Endothelial|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KIF26A CAV1 CAV2 RASA4 CA7

5.03e-05187955a178b1fed80a0bf83aedb6262493ee17374734b5
ToppCelldroplet-Pancreas-Exocrine-24m-Endothelial-endothelial_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KIF26A CAV1 CAV2 RASA4 CA7

5.03e-05187955e60cbccf5842f25123fd34b9475759b7424b32e9
ToppCellTCGA-Head_and_Esophagus-Primary_Tumor-Head_and_Neck_Carcinoma-Squamous_Cell_Carcinoma-9|TCGA-Head_and_Esophagus / Sample_Type by Project: Shred V9

CFAP251 CAV1 CAV2 TENM2 IL4R

5.03e-05187955f002ff1a7cb7577f28acff008bc2aa561ac1a4bf
ToppCelldroplet-Pancreas-Exocrine-24m-Endothelial-endothelial_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KIF26A CAV1 CAV2 RASA4 CA7

5.03e-051879552b8eda2812be0be68a6f01aa4038925d3d5b1e65
ToppCellCOVID-19-Heart-Macrophage|COVID-19 / Disease (COVID-19 only), tissue and cell type

RIN3 ATG7 CD200R1 CD86 SLC38A6

5.29e-051899552586f4088721c5debec86c2b211b739fd33713eb
ToppCellAdult-Epithelial-alveolar_epithelial_cell_type_1-D231|Adult / Lineage, Cell type, age group and donor

CAV1 CAV2 DST NRG3 TMC5

5.29e-051899555a04cb25f8f0447b2cecdb6c3695029281aca26d
ToppCell368C-Epithelial_cells|368C / Donor, Lineage, Cell class and subclass (all cells)

ABO BSPRY TMC5 CA2 SLC22A31

5.43e-05190955459811e88d3001816c2d89034e0921c24918c17f
ToppCelldroplet-Lung-LUNG-1m-Endothelial-Vein_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KIF26A CAV1 CAV2 IGFBPL1 DST

5.56e-051919559fc674a58f20b47255e4457d5195c8cff17b0414
ToppCelldroplet-Lung-LUNG-1m-Endothelial-vein_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KIF26A CAV1 CAV2 IGFBPL1 DST

5.56e-05191955c379a499dabf3c9ed80f47adbb2d949821c5b053
ToppCellSmart-start-Cell-Wel_seq-Neoplastic-Stem-like-OPC-like-OPC-like-F|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

PPEF2 ADGRD2 KIR2DL1 TMC5 CA7

5.84e-05193955315840bc48899f3a36d57b19197509de19716e3d
ToppCelldistal-2-Hematologic-Myeloid_Dendritic_Type_2|2 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

RIN3 CD200R1 SACS CD86 CCR6

5.99e-051949556881cfe12837a32e598535a564e4c31d4846167b
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

CACNA1C GABBR2 TENM2 FOCAD NRG3

6.14e-051959552e1df01bf6e4e98e6cd9fb50926e34c5077b8666
ToppCellDendritic_Cells-IPF_04|World / lung cells shred on cell class, cell subclass, sample id

SLC4A1 HEPACAM RXFP2 CCR6

6.26e-05100954bb7bd11e28be830f381144d4a6f29a86da59d9fa
ToppCellMid-temporal_gyrus_(MTG)-Neuronal|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

CACNA1C GABBR2 TENM2 FOCAD NRG3

6.29e-05196955676c56b44ac29f7baecb62f49bb8597cc74c0a88
ToppCellSomatosensory_Cortex_(S1)-Neuronal|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

CACNA1C GABBR2 TENM2 FOCAD NRG3

6.60e-05198955c01091ef18e096d792ea2a7a715764a5b215355f
ToppCellprimary_auditory_cortex_(A1C)-Neuronal|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

CACNA1C GABBR2 TENM2 FOCAD NRG3

6.60e-051989556d18b45eda4014759e6dd282d78ffd28df8a6044
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

CACNA1C GABBR2 TENM2 FOCAD NRG3

6.60e-051989558ab40fae14fe02e39bc8c8da187a5cd60c787643
ToppCellLPS_anti-TNF-Hematopoietic_Erythro-Megakary-Erythro-Mega-Erythroid|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

AK9 SLC4A1 SLC22A16 MACO1 CA2

6.75e-05199955565404c155dfac57c020a8f2d09cbf756da20ffd
ToppCellLPS_anti-TNF-Epithelial_airway-airway_epithelial-Ciliated|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

SLC4A8 KIF27 CCNO AK9 TMC5

6.75e-0519995515f7814b7074170eee7ccacaa670b1d128fc68bb
ToppCellBiopsy_Other_PF-Epithelial-Transitional_AT2|Biopsy_Other_PF / Sample group, Lineage and Cell type

CAV1 CAV2 GABBR2 TMC5 SLC22A31

6.92e-052009551ba6327851aa61e9a1f1fe1671bc27929d93ac74
ToppCellParenchymal-10x3prime_v2-Epithelial-Epi_submucosal-gland|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

ATG7 BSPRY CA13 XPO5 TMC5

6.92e-0520095568b0f987c4fb8078675475f4f1e71302f832ef69
ToppCellParenchymal-10x3prime_v2-Epithelial-Epi_submucosal-gland-SMG_Duct|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

ATG7 BSPRY CA13 XPO5 TMC5

6.92e-052009551b527bebbca1ef8c52449e40beb9358e37494e04
ToppCellSepsis-ICU-NoSEP-Lymphocyte-T/NK-NK_CD56bright|ICU-NoSEP / Disease, condition lineage and cell class

CA13 TUBGCP5 DNAH14 FOCAD GPR174

6.92e-05200955c2df917900872453ea17a39928e39d071a6d3339
ComputationalIntermediate filaments.

CAV1 CAV2 TENM2 DST CA2

3.83e-0575555MODULE_154
ComputationalIntermediate filaments and keratins.

CAV1 CAV2 TENM2 DST CA2

5.23e-0580555MODULE_357
ComputationalGenes in the cancer module 297.

CAV1 CAV2 TENM2 DST CA2

5.23e-0580555MODULE_297
Drugapraclonidine

CA13 ADRA2B CA2 CA7

8.68e-0718964CID000002216
Drugorthanilamide

CA13 CA2 CA7

1.44e-066963CID000072894
Drugsulfonamide

HTR1D CA13 SLC38A6 CA2 CA7

3.22e-0654965CID000005333
Drugaminozolamide

CA13 CA2 CA7

4.01e-068963CID000093505
DrugL-662,583

CA13 CA2 CA7

4.01e-068963CID003082977
DrugL-643,799

CA13 CA2 CA7

4.01e-068963CID000121595
Drugsezolamide

CA13 CA2 CA7

4.01e-068963CID000060692
Drugmethazolamide

CA13 SLC26A6 CA2 CA7

4.13e-0626964CID000004100
Drugbenzolamide

CA13 SLC4A1 CA2 CA7

5.62e-0628964CID000018794
Drugqassa

CA13 CA2 CA7

5.99e-069963CID003082191
Drug6-hydroxyethoxzolamide

CA13 CA2 CA7

5.99e-069963CID000094706
DrugProntosil

CA13 CA2 CA7

8.53e-0610963CID000066895
Drugmetanilamide

CA13 CA2 CA7

8.53e-0610963CID000007377
Drug1,3-benzenedisulfonamide

CA13 CA2 CA7

8.53e-0610963CID003090044
DrugAC1L8MM4

HTR1D CCNO GABBR2

8.53e-0610963CID000429016
Drugbenzenesulfonamide

CA13 SLC33A1 CA2 CA7

1.11e-0533964CID000007370
DrugCl 13850

CA13 CA2 CA7

1.17e-0511963CID000159459
Drugcobalt phosphate

CA13 CA2 CA7

1.17e-0511963CID000061615
DrugTio-urasin

CA13 CA2 CA7

1.17e-0511963CID000084724
Drugsodium bicarbonate

SLC4A8 CA13 SLC4A1 CA2 CA7

1.54e-0574965CID000010340
Drughydroflumethiazide

CA13 CA2 CA7

1.55e-0512963CID000003647
Drugmafenide acetate

CA13 CA2 CA7

2.01e-0513963CID000003998
Drugchlorzolamide

CA13 CA2 CA7

2.01e-0513963CID000165323
DrugFg 400

CA13 CA2 CA7

2.01e-0513963CID000012443
Drugbendrofluazide

CA13 FURIN CA2 CA7

2.18e-0539964CID000002315
Drugcobalt;sulfide

CA13 CA2 CA7

2.56e-0514963CID000159453
Drugbrimonidine

HTR1D CA13 ADRA2B CA2 CA7

3.19e-0586965CID000002435
Drugsodium

CACNA1C SLC4A8 CA13 BCKDHB IDH1 GABBR2 SLC4A1 SLC32A1 SLC22A16 SACS SLC25A2 FURIN CA2 CA7

4.07e-059449614CID000000923
Drugmetolazone

CA13 CA2 CA7

4.73e-0517963CID000004170
Drugbetaxolol

CA13 ADRA2B CA2 CA7

5.01e-0548964CID000002369
Drugracemic timolol

CA13 ADRA2B CA2 CA7

6.37e-0551964CID000005478
Drugsulthiame

CA13 CA2 CA7

6.70e-0519963CID000005356
Drugcyanate

CCNO CA13 CA2 CA7

8.58e-0555964CID000000540
DrugAC1LCVB4

CA13 CA2 CA7

9.14e-0521963CID000656627
Drugmethyl paraoxon

HTR1D SLC4A1 DST

9.14e-0521963CID000013708
DrugCGP 51176

HTR1D GABBR2

1.05e-044962CID005310935
Drug3-azanylpropylphosphonous acid

HTR1D GABBR2

1.05e-044962CID009989268
DrugI-7B

CA13 CA2

1.05e-044962CID000067136
DrugCGP56433

HTR1D GABBR2

1.05e-044962CID000132966
DrugAABSSN

CA13 CA2 CA7

1.06e-0422963CID005464134
Drugcarbamoyl phosphate

ABO CA13 SLC25A2 CA2 CA7

1.18e-04113965CID000000278
Drugdichlorphenamide

CA13 CA2 CA7

1.21e-0423963CID000003038
DrugHelveticoside [630-64-8]; Down 200; 7.4uM; MCF7; HT_HG-U133A

SLC4A8 IDH1 TFB1M SACS SLC33A1 IL4R

1.30e-041849663945_DN
Drugpotassium cyanate

CA13 CA2 CA7

1.38e-0424963CID011378442
Drugtrans-1,2-diphenylethylene

SLC4A8 CA13 SLC4A1 CA2 CA7

1.38e-04117965CID000011502
Drugfurosemide

SLC4A8 CA13 GABBR2 SLC4A1 FURIN CA2 CA7

1.55e-04272967CID000003440
Drugquisqualamine

HTR1D GABBR2

1.74e-045962CID003085372
Drug4-ABPA

HTR1D GABBR2

1.74e-045962CID000001726
DrugFluticasone propionate [80474-14-2]; Down 200; 8uM; MCF7; HT_HG-U133A

PIM2 GABBR2 MACO1 FURIN INTS15 IL4R

1.84e-041969667348_DN
Drug(+,-)-Synephrine [94-07-5]; Up 200; 24uM; PC3; HT_HG-U133A

RIN3 CTC1 BSPRY SLC30A5 ARHGEF4 IL4R

1.89e-041979667150_UP
DrugBenzonatate [104-31-4]; Down 200; 6.6uM; PC3; HT_HG-U133A

DRAM1 BCKDHB HIRA SLC30A5 TMC5 IL4R

2.05e-042009666334_DN
Diseaselevel of killer cell immunoglobulin-like receptor 2DS2 in blood serum

KIR2DL1 KIR2DL3

2.69e-053892OBA_2042107
DiseaseDiffuse Scleroderma

CAV1 CCR6

8.94e-055892C1258104
DiseaseCREST Syndrome

CAV1 CCR6

1.34e-046892C0206138
DiseaseScleroderma, Limited

CAV1 CCR6

1.34e-046892C0748540
Diseasecomplement factor D measurement

ABO SLC30A5 KIR2DL1 KIR2DL3

1.84e-0493894EFO_0020283
DiseaseSecondary Open Angle Glaucoma

CAV1 CAV2

5.82e-0412892C0271148
DiseaseGlaucoma, Open-Angle

CAV1 CAV2

5.82e-0412892C0017612
DiseaseGlaucoma, Primary Open Angle

CAV1 CAV2

6.87e-0413892C0339573
Diseasehigh grade glioma (biomarker_via_orthology)

CAV1 CAV2

9.21e-0415892DOID:3070 (biomarker_via_orthology)
Diseasekiller cell immunoglobulin-like receptor 2DS2 measurement

KIR2DL1 KIR2DL3

9.21e-0415892EFO_0801746
Diseaseanemia (implicated_via_orthology)

SLC4A8 SLC4A1

9.21e-0415892DOID:2355 (implicated_via_orthology)
Diseasevital capacity

RIN3 ABO DRAM1 BCKDHB AK9 TENM2 DST TULP4 PAN2 SLC38A6 CA2

1.22e-0312368911EFO_0004312
Diseasemultiple sclerosis (is_implicated_in)

CAV1 CD86 IL4R

1.42e-0373893DOID:2377 (is_implicated_in)
DiseaseGraves disease

ABO GPR174 CCR6

1.91e-0381893EFO_0004237
Diseaseprimary open angle glaucoma (is_implicated_in)

CAV1 CAV2

2.18e-0323892DOID:1070 (is_implicated_in)
DiseaseAnhedonia

CACNA1C CCR6

2.38e-0324892C0178417
Diseasesystemic scleroderma (is_implicated_in)

CAV1 CD86

2.38e-0324892DOID:418 (is_implicated_in)
Diseaseopen-angle glaucoma

ABO CAV1 CAV2 DST

2.71e-03191894EFO_0004190

Protein segments in the cluster

PeptideGeneStartEntry
IVVAVPLCVWELQKL

TMEM184C

26

Q9NVA4
VALWLVDPLTVKECV

SLC33A1

466

O00400
KWILSLEEPLCQVGI

BTN2A3P

406

Q96KV6
VLTPCRKDVLVVTPW

ABO

76

P16442
VQLTPLVIDCVKTVW

CTC1

36

Q2NKJ3
PQVTAESRCKLLSWL

CCNO

126

P22674
IICLAVLWVVKSTPA

SLC4A1

841

P02730
CWRKTIITSPESLNL

ARHGEF4

101

Q9NR80
LPRSKIICLVVWGLS

CCR6

161

P51684
PRRIKCIILTVWLIA

ADRA2B

126

P18089
VPPLLESVTWIVLKQ

CA13

201

Q8N1Q1
IPWITAVLPTVIICV

CD86

246

P42081
ILSFLHIWAVVPCIK

CAV1

121

Q03135
KWTLAVETPACTLEL

CFAP251

376

Q8TBY9
VKYWICLALIEPITS

CKAP2

461

Q8WWK9
NEPIIRTATVWKTLC

RASA4

36

O43374
PLLKISCSDTWVIEQ

OR6C2

181

Q9NZP2
NEPIIRTATVWKTLC

RASA4B

36

C9J798
GPLVKSEETVILQCW

KIR2DS2

36

P43631
IIPLAPISKSLWTCS

INTS13

41

Q9NVM9
ELTPLVGLIRWCVKA

INTS15

236

Q96N11
RWIQPSASCDKILVI

LEMD3

746

Q9Y2U8
VCASLISITKLEWNP

DRAM1

176

Q8N682
VRKTISHLPIQLWCV

NRG3

531

P56975
TIIPWDVDTICKSVI

BCKDHB

306

P21953
IWECLPGKVNITVVA

OVOS1

716

Q6IE37
VKPSWVILSVQCGTL

PAXIP1

71

Q6ZW49
LVCPSIEELKNVWLP

PAN2

796

Q504Q3
VCIQLIIASWTITIP

OR10AG1

131

Q8NH19
KVLWLTASQPCSIVD

LPCAT4

251

Q643R3
WIDKCRPNLLITEST

INTS11

191

Q5TA45
GPLVKSEETVILQCW

KIR2DL3

36

P43628
WLTTIEKRLVNCEPI

DST

5516

Q03001
LRTLCIEVWPVLAVI

HERC1

2296

Q15751
TERGVCLPTVSLWIL

MACO1

116

Q8N5G2
WIQKPDSVCSLVELS

KIF27

666

Q86VH2
WDTPLIVIIVLAGSC

PCDH8

746

O95206
CWLIRLCISIVVLPK

HEATR6

651

Q6AI08
CEVRAVPTPVITWRK

IGFBPL1

176

Q8WX77
IVPCAISWLFRLIEE

KIF26A

491

Q9ULI4
CPPIALRNLIIITWE

CD200R1

61

Q8TD46
IITWEIILRGQPSCT

CD200R1

71

Q8TD46
PWPVDIVISLECQKI

TUBGCP5

806

Q96RT8
TPLLIVLYCTWKTVL

GPR174

196

Q9BXC1
GPLVKSEETVILQCW

KIR2DS5

36

Q14953
AIICKNIPRLVSGWV

IDH1

111

O75874
LWPESISVVRCVELF

IL4R

351

P24394
CWRLVPTLDLDKVVS

ATG7

341

O95352
EKCTRSPLLTQLWAT

BSPRY

206

Q5W0U4
ACISIVEWKPFEIII

CACNA1C

116

Q13936
WTTVAPQRKCIIDIL

FURIN

441

P09958
IVWAISICISIPPLF

HTR1D

161

P28221
RLVITPLTDRCWLTL

DNAH14

1136

Q0VDD8
ILICWQAVDPLRRTV

GABBR2

611

O75899
FLLVTLVTVCACWKP

HEPACAM

251

Q14CZ8
SESVTWIVLREPICI

CA7

206

P43166
CSSWSLSPVILIKVV

CRYBG1

1046

Q9Y4K1
LSPVILIKVVRGCWI

CRYBG1

1051

Q9Y4K1
VWLTCLKRPLVVIHE

HIRA

311

P54198
TIWKSVTDVIIAPLC

CAV2

131

P51636
TTWIIPFISPILIIC

ERVFC1

516

P60507
WVPCIVLGLVLSSEE

SLC22A31

26

A6NKX4
VLQLLWTSCPILPEK

SACS

3696

Q9NZJ4
GPLVKSEETVILQCW

KIR2DL1

36

P43626
LWLLCVSVPQALPKA

CDH16

6

O75309
VVCIRSTWNALSPKL

FOCAD

641

Q5VW36
CWLPLATLIDEKVLI

PPEF2

276

O14830
LIKTCPVWLQLSLGQ

RIN3

56

Q8TB24
TQAWKCIRVEALPIL

AK9

51

Q5TCS8
LVLPLSTIRSVESCW

TAAR5

86

O14804
TVTVPFILCCWVLPE

SLC22A16

276

Q86VW1
LSLIYTVLEVCWKLP

SLC26A6

246

Q9BXS9
DSVTCPLEVALLWKV

PIM2

76

Q9P1W9
DLFTKWIVILPLCDV

GIN1

166

Q9NXP7
WIVILPLCDVSASEV

GIN1

171

Q9NXP7
ALVVIIKKWSIPCPL

SLC38A6

206

Q8IZM9
TCDLLPLKAWLDTIT

SLITRK2

221

Q9H156
SDAICWIPVFVVKIL

RXFP2

646

Q8WXD0
VSTPLIIKWLENISC

TFB1M

146

Q8WVM0
ETCPSLILWEKRTAL

TENM2

1151

Q9NT68
VLCLTVIPKVLTIFW

OR56A3

76

Q8NH54
EKCILVITWIQHLIP

PSME2

116

Q9UL46
TCLVLLWVIKASPAA

SLC4A8

961

Q2Y0W8
ICLWLVVFPVDCIKS

SLC25A2

221

Q9BXI2
VTPSLLPTVWVRLLC

ADGRD2

311

Q7Z7M1
SLTTPPLLECVTWIV

CA2

196

P00918
PLLECVTWIVLKEPI

CA2

201

P00918
TALGTPLWIKATVLC

CLRN1

26

P58418
TLDTLVQRPIISICW

TULP4

336

Q9NRJ4
TEPHCIIINLSTWII

USP45

111

Q70EL2
RTTSQLCWPLLKQVL

XPO5

1046

Q9HAV4
VQNWLVEVPIVSPIC

ERVK-11

936

Q9UQG0
EVEVNCKWILPILTQ

PRAMEF11

211

O60813
VLACSLPQVFLKPWI

KRT10-AS1

46

Q8N816
TIPVIKRLLLLCWSV

TAAR2

156

Q9P1P5
WVIPALKQIREICSL

USP9Y

566

O00507
STKIWFVIELCEPIQ

SUCO

346

Q9UBS9
VLLLCPWVIVLSVTT

SLC30A5

246

Q8TAD4
TLAITIWRLKPSADC

TMC5

851

Q6UXY8
KSWSIIATAVLLPCA

SLC32A1

241

Q9H598
GPLEVLCITIWRTLE

XKRX

236

Q6PP77
IPTCLATWKIAIAAE

ZFC3H1

1901

O60293
CRRVLSWVPVLVIVL

ZDHHC15

16

Q96MV8
TCKSVTPEWVLQDLI

NLRP13

761

Q86W25