Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionactin binding

SHROOM4 DST SPATA31A1 SPATA31A3 MYH7B MYO18A MACF1 SPATA31A6 SPATA31A5 IQGAP3

1.48e-064796010GO:0003779
GeneOntologyMolecularFunctioncytoskeletal protein binding

SHROOM4 DES HOOK3 DST SPATA31A1 SPATA31A3 BRCA1 ANK3 MYH7B MYO18A MACF1 SPATA31A6 SPATA31A5 IQGAP3

3.46e-0610996014GO:0008092
GeneOntologyMolecularFunctionATP-dependent activity

MYH7B DNAH17 MYO18A MACF1 DDX3Y HFM1 ZRANB3 NLRP3

4.77e-04614608GO:0140657
GeneOntologyMolecularFunctionactin filament binding

SHROOM4 MYH7B MYO18A MACF1 IQGAP3

5.97e-04227605GO:0051015
GeneOntologyCellularComponentacrosomal vesicle

LRGUK SPATA31A1 SPATA31A3 CYP51A1 SPATA31A6 TRIP11 SPATA31A5

2.02e-06206607GO:0001669
GeneOntologyCellularComponentintercalated disc

AKAP6 DES DST ANK3

4.35e-0568604GO:0014704
GeneOntologyCellularComponenttype III intermediate filament

DES DST

1.21e-046602GO:0045098
GeneOntologyCellularComponentcell-cell contact zone

AKAP6 DES DST ANK3

1.54e-0494604GO:0044291
GeneOntologyCellularComponentcardiac myofibril

DES MYH7B

2.88e-049602GO:0097512
GeneOntologyCellularComponentactomyosin

SHROOM4 DST MYO18A RAI14

3.57e-04117604GO:0042641
GeneOntologyCellularComponentendoplasmic reticulum-Golgi intermediate compartment

MYO18A TRIP11 GOLGA3 GOLGB1

7.22e-04141604GO:0005793
GeneOntologyCellularComponentactin cytoskeleton

DOCK5 SHROOM4 DST MYH7B MYO18A MACF1 RAI14

1.27e-03576607GO:0015629
GeneOntologyCellularComponentsupramolecular fiber

SHROOM4 DES HOOK3 DST ANK3 MYH7B DNAH17 MYO18A MACF1 EFHB

1.80e-0311796010GO:0099512
GeneOntologyCellularComponentcis-Golgi network

HOOK3 TRIP11 GOLGB1

1.88e-0385603GO:0005801
GeneOntologyCellularComponentsupramolecular polymer

SHROOM4 DES HOOK3 DST ANK3 MYH7B DNAH17 MYO18A MACF1 EFHB

1.89e-0311876010GO:0099081
GeneOntologyCellularComponentsarcolemma

AKAP6 DES DST ANK3

2.17e-03190604GO:0042383
GeneOntologyCellularComponentmyosin filament

MYH7B MYO18A

2.33e-0325602GO:0032982
GeneOntologyCellularComponentmyosin II complex

MYH7B MYO18A

2.92e-0328602GO:0016460
GeneOntologyCellularComponentperinuclear endoplasmic reticulum

DST OSBPL3

3.13e-0329602GO:0097038
GeneOntologyCellularComponentcontractile actin filament bundle

SHROOM4 DST RAI14

3.61e-03107603GO:0097517
GeneOntologyCellularComponentstress fiber

SHROOM4 DST RAI14

3.61e-03107603GO:0001725
DomainSpectrin/alpha-actinin

AKAP6 DST MCF2 MACF1

2.82e-0632584IPR018159
DomainSPEC

AKAP6 DST MCF2 MACF1

2.82e-0632584SM00150
DomainDUF4599

SPATA31A3 SPATA31A6 SPATA31A5

6.13e-0612583PF15371
DomainDUF4599

SPATA31A3 SPATA31A6 SPATA31A5

6.13e-0612583IPR027970
DomainSpectrin_repeat

DST MCF2 MACF1

9.81e-0529583IPR002017
DomainGAR

DST MACF1

1.41e-046582PS51460
Domain-

DST MACF1

1.41e-0465823.30.920.20
Domain-

DST MACF1

1.41e-0465823.90.1290.10
DomainGAS_dom

DST MACF1

1.41e-046582IPR003108
DomainGAS2

DST MACF1

1.41e-046582PF02187
DomainGAS2

DST MACF1

1.41e-046582SM00243
DomainPlectin_repeat

DST MACF1

1.97e-047582IPR001101
DomainPlectin

DST MACF1

1.97e-047582PF00681
DomainPLEC

DST MACF1

1.97e-047582SM00250
DomainCH

DST MACF1 IQGAP3

1.08e-0365583SM00033
DomainCH

DST MACF1 IQGAP3

1.34e-0370583PF00307
Domain-

DST MACF1 IQGAP3

1.40e-03715831.10.418.10
DomainMyosin_tail_1

MYH7B MYO18A

1.40e-0318582PF01576
DomainMyosin_tail

MYH7B MYO18A

1.40e-0318582IPR002928
DomainCH

DST MACF1 IQGAP3

1.52e-0373583PS50021
DomainLeu-rich_rpt

LRGUK LRRC45 LRRC70 LRRC8D NLRP3

1.52e-03271585IPR001611
DomainMyosin-like_IQ_dom

MYH7B MYO18A

1.57e-0319582IPR027401
Domain-

MYH7B MYO18A

1.57e-03195824.10.270.10
DomainCH-domain

DST MACF1 IQGAP3

1.64e-0375583IPR001715
DomainIQ

MYH7B MYO18A IQGAP3

2.04e-0381583SM00015
DomainActinin_actin-bd_CS

DST MACF1

2.30e-0323582IPR001589
DomainACTININ_2

DST MACF1

2.30e-0323582PS00020
DomainACTININ_1

DST MACF1

2.30e-0323582PS00019
DomainSpectrin

DST MACF1

2.30e-0323582PF00435
DomainEF-hand_7

DST MACF1 EFHB

2.34e-0385583PF13499
DomainIQ_motif_EF-hand-BS

MYH7B MYO18A IQGAP3

2.76e-0390583IPR000048
Domain-

THOC1 ANK3 NLRP3

3.03e-03935831.10.533.10
DomainIQ

MYH7B MYO18A IQGAP3

3.03e-0393583PS50096
Domain-

LRGUK LRRC45 LRRC70 LRRC8D NLRP3

3.16e-033215853.80.10.10
DomainDEATH

THOC1 ANK3

3.16e-0327582SM00005
DomainL_dom-like

LRGUK LRRC45 LRRC70 LRRC8D NLRP3

3.47e-03328585IPR032675
DomainDEATH-like_dom

THOC1 ANK3 NLRP3

3.61e-0399583IPR011029
DomainP-loop_NTPase

LRGUK GIMAP8 MYH7B MYO18A DDX3Y HFM1 ZRANB3 NLRP3

4.48e-03848588IPR027417
DomainHelicase_C

DDX3Y HFM1 ZRANB3

4.49e-03107583PF00271
DomainHELICc

DDX3Y HFM1 ZRANB3

4.49e-03107583SM00490
DomainHelicase_C

DDX3Y HFM1 ZRANB3

4.61e-03108583IPR001650
DomainDeath

THOC1 ANK3

4.70e-0333582PF00531
DomainHELICASE_CTER

DDX3Y HFM1 ZRANB3

4.73e-03109583PS51194
DomainHELICASE_ATP_BIND_1

DDX3Y HFM1 ZRANB3

4.73e-03109583PS51192
DomainDEXDc

DDX3Y HFM1 ZRANB3

4.73e-03109583SM00487
DomainLRR_1

LRGUK LRRC45 LRRC70 LRRC8D

4.76e-03219584PF00560
DomainHelicase_ATP-bd

DDX3Y HFM1 ZRANB3

4.85e-03110583IPR014001
DomainDeath_domain

THOC1 ANK3

6.20e-0338582IPR000488
DomainMYOSIN_MOTOR

MYH7B MYO18A

6.20e-0338582PS51456
DomainDEATH_DOMAIN

THOC1 ANK3

6.20e-0338582PS50017
DomainMyosin_head

MYH7B MYO18A

6.20e-0338582PF00063
DomainMyosin_head_motor_dom

MYH7B MYO18A

6.20e-0338582IPR001609
DomainMYSc

MYH7B MYO18A

6.20e-0338582SM00242
PathwayREACTOME_SIGNALING_BY_FLT3_FUSION_PROTEINS

MYO18A TRIP11 GOLGB1

1.57e-0519373M41732
PathwayREACTOME_FLT3_SIGNALING_IN_DISEASE

MYO18A TRIP11 GOLGB1

5.21e-0528373M41724
Pubmed

The testis-specific VAD1.3/AEP1 interacts with β-actin and syntaxin 1 and directs peri-nuclear/Golgi expression with bipartite nucleus localization (BNL) sequence.

SPATA31A1 SPATA31A3 SPATA31A6 SPATA31A5

1.28e-10661420850414
Pubmed

Targeted disruption of the spermatid-specific gene Spata31 causes male infertility.

SPATA31A1 SPATA31A3 SPATA31A6 SPATA31A5

1.28e-10661425930072
Pubmed

Majority of cerebrospinal fluid-contacting neurons in the spinal cord of C57Bl/6N mice is present in ectopic position unlike in other studied experimental mice strains and mammalian species.

SPATA31A1 SPATA31A3 SPATA31A6 SPATA31A5

8.86e-082461432212159
Pubmed

Meta-analysis of genome-wide association data of bipolar disorder and major depressive disorder.

THOC1 COLEC12 ANK3

8.39e-071161320351715
Pubmed

A protein interaction landscape of breast cancer.

THOC1 DST BRCA1 ANK3 MYO18A MACF1 RAI14 SCAF11 TRIP11

1.57e-0663461934591612
Pubmed

Acf7 (MACF) is an actin and microtubule linker protein whose expression predominates in neural, muscle, and lung development.

DST MACF1

3.03e-06261211002341
Pubmed

QKI is a critical pre-mRNA alternative splicing regulator of cardiac myofibrillogenesis and contractile function.

DST ANK3 RAI14

5.73e-062061333397958
Pubmed

Analysis of interaction partners for eukaryotic translation elongation factor 1A M-domain by functional proteomics.

DST DNAH17 MACF1

5.73e-062061321689717
Pubmed

Defining the proximal interaction networks of Arf GTPases reveals a mechanism for the regulation of PLD1 and PI4KB.

DOCK5 ARFGEF3 DST BRCA1 ANK3 RAI14 TRIP11 GOLGA3 GOLGB1

8.13e-0677761935844135
Pubmed

A Multipronged Unbiased Strategy Guides the Development of an Anti-EGFR/EPHA2-Bispecific Antibody for Combination Cancer Therapy.

DST ANK3 MACF1 RAI14 TRIP11 GOLGA3 GOLGB1

9.00e-0642161736976175
Pubmed

Expression of the mouse Macf2 gene during inner ear development.

DST MACF1

9.07e-06361212399109
Pubmed

Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.

AKAP6 ODF2L DST ANK3 USP25 TTC27 MACF1 RAI14 ZFC3H1 TRIP11 GOLGA3

1.29e-051285611135914814
Pubmed

Arf GTPase-activating protein ASAP1 interacts with Rab11 effector FIP3 and regulates pericentrosomal localization of transferrin receptor-positive recycling endosome.

MACF1 RAI14 GOLGB1

1.46e-052761318685082
Pubmed

Cloning and characterization of mouse ACF7, a novel member of the dystonin subfamily of actin binding proteins.

DST MACF1

1.81e-0546128954775
Pubmed

The atypical Rac activator Dock180 (Dock1) regulates myoblast fusion in vivo.

DOCK5 DES

1.81e-05461218820033
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

SHROOM4 OSBPL3 DNAH17 MACF1 ZFC3H1 TRAPPC8 MAML3

2.48e-0549361715368895
Pubmed

The protein network surrounding the human telomere repeat binding factors TRF1, TRF2, and POT1.

DST POT1 MACF1 DDX3Y SRSF11

2.55e-0519761520811636
Pubmed

C5orf51 is a component of the MON1-CCZ1 complex and controls RAB7A localization and stability during mitophagy.

ARFGEF3 DST CYP51A1 RAI14 TRIP11 GOLGA3 GOLGB1

2.86e-0550461734432599
Pubmed

Restoration of Replication Fork Stability in BRCA1- and BRCA2-Deficient Cells by Inactivation of SNF2-Family Fork Remodelers.

BRCA1 ZRANB3

3.02e-05561229053959
Pubmed

Voltage-dependent conformational changes of Kv1.3 channels activate cell proliferation.

CCDC73 MYH7B MYO18A IQGAP3 GOLGB1

3.30e-0520861533230847
Pubmed

Prediction of the coding sequences of unidentified human genes. XV. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.

ARFGEF3 SHROOM4 ODF2L MACF1

3.32e-0510361410574462
Pubmed

Interactomes of Glycogen Synthase Kinase-3 Isoforms.

ARFGEF3 TDRD3 DST MACF1 GOLGA3

3.38e-0520961536779422
Pubmed

N-Terminomics for the Identification of In Vitro Substrates and Cleavage Site Specificity of the SARS-CoV-2 Main Protease.

DST MACF1 SRSF11 TRIP11 GOLGA3 GOLGB1

4.05e-0536061633111431
Pubmed

Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.

TDRD3 HOOK3 DST ANK3 OSBPL3 MACF1 TRIP11 GOLGA3 GOLGB1

4.40e-0596361928671696
Pubmed

Intersectin (ITSN) family of scaffolds function as molecular hubs in protein interaction networks.

DES DST RAI14 GOLGB1

4.46e-0511161422558309
Pubmed

Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.

DOCK5 ARFGEF3 ODF2L ANK3 MACF1 SRSF11 RAI14 SCAF11 LRRC8D MAML3 GOLGB1

4.97e-051489611128611215
Pubmed

E-cadherin interactome complexity and robustness resolved by quantitative proteomics.

DST ANK3 MACF1 RAI14 TRIP11 GOLGA3 GOLGB1

5.88e-0556561725468996
Pubmed

Vti1b promotes TRPV1 sensitization during inflammatory pain.

DST OSBPL3 DDX3Y RAI14

7.53e-0512761430335684
Pubmed

Novel obscurins mediate cardiomyocyte adhesion and size via the PI3K/AKT/mTOR signaling pathway.

DES ANK3

8.42e-05861228826662
Pubmed

Inflammation-dependent overexpression of c-Myc enhances CRL4DCAF4 E3 ligase activity and promotes ubiquitination of ST7 in colitis-associated cancer.

PHKA2 USP25 PRR14L GOLGB1 NLRP3

8.99e-0525761530945288
Pubmed

PHF11 promotes DSB resection, ATR signaling, and HR.

BRCA1 POT1

1.08e-04961228115467
Pubmed

BRCA1 binds TERRA RNA and suppresses R-Loop-based telomeric DNA damage.

BRCA1 POT1

1.08e-04961234112789
Pubmed

Accelerating functional gene discovery in osteoarthritis.

DNAH17 SCAF11 LRRC8D

1.13e-045361333473114
Pubmed

A central chaperone-like role for 14-3-3 proteins in human cells.

ARFGEF3 DST OSBPL3 MACF1 SRSF11 RAI14 TRIP11 GOLGB1

1.26e-0486161836931259
Pubmed

TDRD3, a novel Tudor domain-containing protein, localizes to cytoplasmic stress granules.

TDRD3 DDX3Y

1.35e-041061218632687
Pubmed

Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein.

DOCK5 UBR1 PHKA2 DST OSBPL3 SRSF11 IQGAP3

1.40e-0465061738777146
Pubmed

Disrupted in Schizophrenia 1 Interactome: evidence for the close connectivity of risk genes and a potential synaptic basis for schizophrenia.

AKAP6 COLEC12 DST MACF1

1.47e-0415161417043677
Pubmed

53BP1-RIF1-shieldin counteracts DSB resection through CST- and Polα-dependent fill-in.

BRCA1 POT1

1.65e-041161230022158
Pubmed

The role of microtubule actin cross-linking factor 1 (MACF1) in the Wnt signaling pathway.

DST MACF1

1.65e-041161216815997
Pubmed

In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.

DES DST BRCA1 MYH7B MYO18A MACF1 SRSF11 ZFC3H1 GOLGB1 CCDC158

1.91e-041442611035575683
Pubmed

A human MAP kinase interactome.

DES DST ANK3 MYO18A MACF1 GOLGB1

2.09e-0448661620936779
Pubmed

A human skeletal muscle interactome centered on proteins involved in muscular dystrophies: LGMD interactome.

AKAP6 DES HOOK3 DST MACF1 TRIP11

2.36e-0449761623414517
Pubmed

Chemical Crosslinking Mass Spectrometry Analysis of Protein Conformations and Supercomplexes in Heart Tissue.

DES DST ANK3 MYH7B MYO18A

2.91e-0433161529199018
Pubmed

Angiopoietin-1 is essential in mouse vasculature during development and in response to injury.

DES ANGPTL1

3.13e-041561221606590
Pubmed

Kelch Domain of Gigaxonin Interacts with Intermediate Filament Proteins Affected in Giant Axonal Neuropathy.

DST CCDC73 MYO18A ZFC3H1

3.32e-0418761426460568
Pubmed

Characterization of an exchangeable gene trap using pU-17 carrying a stop codon-beta geo cassette.

TDRD3 OSBPL3 SRSF11 RAI14 SCAF11 LRRC8D

3.53e-0453661615840001
Pubmed

The E3 ubiquitin ligase HECTD1 contributes to cell proliferation through an effect on mitosis.

THOC1 TDRD3 MYO18A MACF1 SCAF11 ZFC3H1 IQGAP3

3.60e-0475961735915203
Pubmed

Exchangeable gene trap using the Cre/mutated lox system.

TDRD3 OSBPL3 SRSF11 RAI14 SCAF11 LRRC8D

3.60e-0453861610512203
Pubmed

Spatial proteomics reveal that the protein phosphatase PTP1B interacts with and may modify tyrosine phosphorylation of the rhomboid protease RHBDL4.

DST RAI14 TRIP11 GOLGB1

3.60e-0419161431177093
Pubmed

Faciogenital Dysplasia 5 supports cancer stem cell traits in basal-like breast cancer by enhancing EGFR stability.

DST MYO18A MACF1 RAI14

3.60e-0419161433762435
Pubmed

H4K20me0 recognition by BRCA1-BARD1 directs homologous recombination to sister chromatids.

THOC1 DOCK5 DST BRCA1 OSBPL3 POT1 SRSF11 SCAF11 ZFC3H1

4.04e-04129461930804502
Pubmed

SR protein kinases promote splicing of nonconsensus introns.

ARFGEF3 ANK3 MACF1 SRSF11 ZFC3H1

4.33e-0436161526167880
Pubmed

RSPO-LGR4 functions via IQGAP1 to potentiate Wnt signaling.

SCAF11 ZFC3H1 IQGAP3 GOLGA3

4.45e-0420261424639526
Pubmed

Proteomic analysis of steady-state nuclear hormone receptor coactivator complexes.

PHKA2 TRIP11 GOLGA3

4.58e-048561316051665
Pubmed

Comparative proximity biotinylation implicates the small GTPase RAB18 in sterol mobilization and biosynthesis.

DST CYP51A1 RAI14 PRR14L TRAPPC8 TRIP11

4.79e-0456861637774976
Pubmed

Splicing factor TRA2B is required for neural progenitor survival.

SRSF11 SCAF11

5.08e-041961223818142
Pubmed

The deubiquitinase TRABID stabilizes the K29/K48-specific E3 ubiquitin ligase HECTD1.

UBR1 DST ZFC3H1 TRIP11

5.34e-0421261433853758
Pubmed

Genome-wide CRISPR screens identify novel regulators of wild-type and mutant p53 stability.

ARFGEF3 TDRD3 ODF2L MACF1 TRIP11 GOLGB1

5.75e-0458861638580884
Pubmed

Functional proteomics mapping of a human signaling pathway.

PHKA2 DST ANK3 USP25 MACF1 GOLGB1

5.90e-0459161615231748
Pubmed

Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method.

AKAP6 ANK3 TAGAP OSBPL3 MACF1 DDX3Y ZRANB3 GOLGB1

5.91e-04108461811544199
Pubmed

α-Dystrobrevin distribution and association with other proteins in human promyelocytic NB4 cells treated for granulocytic differentiation.

DES BRCA1

6.83e-042261220111909
Pubmed

p16 Protein and gigaxonin are associated with the ubiquitination of NFκB in cisplatin-induced senescence of cancer cells.

SPATA31A3 MAP3K8

6.83e-042261225331947
Pubmed

The ATG5 interactome links clathrin-mediated vesicular trafficking with the autophagosome assembly machinery.

DOCK5 UBR1 HOOK3 MYO18A

7.24e-0423061435449600
Pubmed

USP7 targets XIAP for cancer progression: Establishment of a p53-independent therapeutic avenue for glioma.

DST MACF1 RAI14 GOLGB1

7.72e-0423461436243803
Pubmed

Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.

DST TTC27 RAI14 GOLGA3 GOLGB1

8.38e-0441861534709266
Pubmed

Defining the membrane proteome of NK cells.

OSBPL3 INPP5K CYP51A1 MYO18A DDX3Y LRRC8D GOLGA3 GOLGB1

9.60e-04116861819946888
Pubmed

Proteomic and Biochemical Comparison of the Cellular Interaction Partners of Human VPS33A and VPS33B.

ARFGEF3 TDRD3 ANK3 TRIP11

1.00e-0325161429778605
Pubmed

Disruption of Trip11 in cranial neural crest cells is associated with increased ER and Golgi stress contributing to skull defects in mice.

TRIP11 GOLGB1

1.03e-032761235147267
Pubmed

The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.

TDRD3 DST BRCA1 MACF1 RAI14 SCAF11 ZFC3H1 IQGAP3 GOLGB1

1.14e-03149761931527615
Pubmed

RNF43 inhibits WNT5A-driven signaling and suppresses melanoma invasion and resistance to the targeted therapy.

ANK3 MACF1 TRIP11 GOLGB1

1.19e-0326361434702444
Pubmed

N-Terminal Acetyltransferase Naa40p Whereabouts Put into N-Terminal Proteoform Perspective.

TDRD3 DST MACF1 RAI14 PRR14L TRIP11 GOLGB1

1.22e-0393461733916271
Pubmed

HENA, heterogeneous network-based data set for Alzheimer's disease.

DST MACF1 ZFC3H1

1.25e-0312061331413325
Pubmed

Multiple roles of FOXJ3 in spermatogenesis: A lesson from Foxj3 conditional knockout mouse models.

BRCA1 HFM1

1.45e-033261227739607
Pubmed

Targeting USP10 induces degradation of oncogenic ANLN in esophageal squamous cell carcinoma.

THOC1 DST INPP5K MYO18A RAI14 SCAF11 ZFC3H1 IQGAP3

1.53e-03125761836526897
Pubmed

An Interaction Landscape of Ubiquitin Signaling.

DST BRCA1 USP25 MACF1 ZRANB3

1.56e-0348161528190767
Pubmed

A BioID-Derived Proximity Interactome for SARS-CoV-2 Proteins.

HOOK3 OSBPL3 MYO18A MACF1 RAI14 TRAPPC8

1.62e-0371961635337019
Pubmed

A quantitative telomeric chromatin isolation protocol identifies different telomeric states.

THOC1 POT1

1.64e-033461224270157
Pubmed

HAUSP regulates c-MYC expression via de-ubiquitination of TRRAP.

MACF1 GOLGB1

1.64e-033461225925205
Pubmed

A Degradation Motif in STAU1 Defines a Novel Family of Proteins Involved in Inflammation.

THOC1 TDRD3 BRCA1 MYO18A MACF1 ZFC3H1

1.67e-0372461636232890
InteractionLCK interactions

DST BRCA1 ANK3 MAP3K8 MACF1 RAI14 TRIP11 GOLGA3 GOLGB1

6.47e-06463589int:LCK
InteractionMYL6 interactions

DES HOOK3 MYO18A USP25 TRAPPC8 IQGAP3 NLRP3

8.30e-06255587int:MYL6
InteractionPROSER2 interactions

UBR1 ANK3 INPP5K POT1

2.18e-0557584int:PROSER2
InteractionEBAG9 interactions

HOOK3 DST ANK3 TRAPPC8 TRIP11 GOLGA3 GOLGB1

2.53e-05303587int:EBAG9
InteractionSTX6 interactions

DST ANK3 MACF1 RAI14 TRAPPC8 TRIP11 GOLGA3 GOLGB1

4.05e-05448588int:STX6
InteractionLTK interactions

DST RAI14 TRIP11 GOLGA3 GOLGB1

7.59e-05152585int:LTK
InteractionLAMP1 interactions

PHKA2 DST MYO18A MACF1 RAI14 TRAPPC8 TRIP11 GOLGA3 GOLGB1

8.63e-05644589int:LAMP1
InteractionGAN interactions

DES DST CCDC73 INPP5K MYO18A ZFC3H1

8.65e-05253586int:GAN
InteractionSTX7 interactions

ARFGEF3 COLEC12 DST ANK3 RAI14 TRAPPC8 TRIP11 GOLGA3 GOLGB1

1.03e-04659589int:STX7
Cytoband10p11.23

ZNF438 MAP3K8

2.62e-041861210p11.23
Cytoband9p13.1

SPATA31A1 SPATA31A3

4.70e-04246129p13.1
Cytoband1p22.2

HFM1 LRRC8D

6.42e-04286121p22.2
CytobandEnsembl 112 genes in cytogenetic band chr1p22

ODF2L HFM1 LRRC8D

8.24e-04137613chr1p22
GeneFamilyEF-hand domain containing|Plakins

DST MACF1

1.26e-048392939
CoexpressionCUI_TCF21_TARGETS_2_DN

DOCK5 ARFGEF3 COLEC12 DST GIMAP8 MYO18A USP25 MCF2 MACF1 TRIP11 GOLGA3

2.76e-068545911M1533
CoexpressionCUI_TCF21_TARGETS_2_DN

DOCK5 ARFGEF3 COLEC12 DST GIMAP8 MYO18A USP25 MCF2 MACF1 TRIP11 GOLGA3

4.01e-068885911MM1018
CoexpressionHAMAI_APOPTOSIS_VIA_TRAIL_UP

TDRD3 BRCA1 USP25 SRSF11 RAI14 SCAF11 TRAPPC8 TRIP11 GOLGB1

1.50e-05656599M18979
CoexpressionGSE40493_BCL6_KO_VS_WT_TREG_UP

TTC27 ZFC3H1 ANGPTL1 GOLGA3 NLRP3

4.95e-05177595M9401
CoexpressionAIZARANI_LIVER_C20_LSECS_3

SHROOM4 MACF1 DDX3Y RAI14 GOLGB1 CCDC144A

5.27e-05295596M39121
CoexpressionNIKOLSKY_MUTATED_AND_AMPLIFIED_IN_BREAST_CANCER

HOOK3 MYH7B DNAH17 ZFC3H1

6.07e-0594594M18108
CoexpressionGSE21927_C26GM_VS_4T1_TUMOR_MONOCYTE_BALBC_DN

MACF1 SRSF11 SCAF11 ZFC3H1 TRAPPC8

8.61e-05199595M7607
CoexpressionGSE10240_CTRL_VS_IL22_STIM_PRIMARY_BRONCHIAL_EPITHELIAL_CELLS_UP

DOCK5 GIMAP8 MYO18A PRR14L NLRP3

8.82e-05200595M302
CoexpressionLAKE_ADULT_KIDNEY_C2_PODOCYTES

DOCK5 DST MACF1 RAI14 MAML3

1.16e-04212595M39221
ToppCelldroplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DST MACF1 DDX3Y SCAF11 TRIP11 GOLGB1

2.79e-071956167796ea9247f4c63762f0de8490fed08b9717fa23
ToppCelldroplet-Limb_Muscle-MUSCLE-30m-Mesenchymal|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COLEC12 DES DDX3Y SCAF11 TRIP11 ANGPTL1

2.79e-071956165c86fddd6d0530beecf45ea5ba6b823123847696
ToppCellmild-low-quality_cells|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

ODF2L ANK3 MACF1 SRSF11 ZFC3H1 GOLGB1

3.15e-07199616f0b0097df0026496470a80d8cc9375ffd8389b00
ToppCelldroplet-Heart-nan-3m|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

AKAP6 MACF1 SCAF11 TRIP11 GOLGA3

4.31e-06176615749b47eac5436fa34e0d243ffbc6f1897f4e431e
ToppCellLV-15._Ventricular_Cardiomyocyte_III|LV / Chamber and Cluster_Paper

AKAP6 DES DST ANK3 MYH7B

5.35e-06184615ab7a1620c14a9d9b6be1b47c559931e345e9eef8
ToppCellfacs-Brain_Myeloid-Hippocampus-3m-Myeloid|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HOOK3 DST TAGAP MACF1 SCAF11

6.75e-0619361506b65110db974f4ef90d3511ff34428976a52c9c
ToppCellfacs-Brain_Myeloid-Hippocampus-3m-Myeloid-microglial_cell|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HOOK3 DST TAGAP MACF1 SCAF11

6.75e-061936159c16032bc03df8760ae199e8f19fdafa4c3f1827
ToppCellSevere_COVID-19-Myeloid-proliferating_Myeloid_cells|Severe_COVID-19 / Disease group,lineage and cell class (2021.01.30)

COLEC12 DST BRCA1 ANGPTL1 IQGAP3

6.75e-061936150d85025690c9cd545cba30abc38acbdd6a39b153
ToppCellfacs-Brain_Myeloid-Hippocampus-3m|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HOOK3 DST TAGAP MACF1 SCAF11

6.75e-06193615a4f91bca5eaa985982d33a528f7566ffde154d47
ToppCellfacs-Brain_Myeloid-Hippocampus-3m-Myeloid-nan|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HOOK3 DST TAGAP MACF1 SCAF11

6.75e-06193615b39d7feaac4ff8f7409cd3d15e8f3c6391367275
ToppCell10x_3'_v2v3-Non-neoplastic-Glial-Neuronal-Oligodendrocyte-Oligodendrocyte-E|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

AKAP6 DOCK5 ARFGEF3 SHROOM4 ANK3

6.92e-06194615cb0422e7607dbd77204428b7e2c70dfe14a6ca11
ToppCellBAL-Severe-Myeloid-Myeloid-proliferating_Myeloid_cells|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

COLEC12 DST BRCA1 ANGPTL1 IQGAP3

6.92e-06194615cb39850e9577015b6b9834e98c36b412bae7d462
ToppCellBAL-Severe-Myeloid-Myeloid-proliferating_Myeloid_cells-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

COLEC12 DST BRCA1 ANGPTL1 IQGAP3

6.92e-06194615408597c9aa302a44b112c1d612c21fbb0227a82a
ToppCellBAL-Severe-Myeloid-Myeloid-proliferating_Myeloid_cells-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

COLEC12 DST BRCA1 ANGPTL1 IQGAP3

6.92e-06194615193cc20fefbd795a4ad59e401a95af47d30603e7
ToppCellBAL-Severe-Myeloid-Myeloid|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

COLEC12 DST BRCA1 ANGPTL1 IQGAP3

6.92e-061946152360b5f995b360419de41612368cab9fb61781a1
ToppCellBAL-Severe-Myeloid-Myeloid-proliferating_Myeloid_cells|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)

COLEC12 DST BRCA1 ANGPTL1 IQGAP3

6.92e-06194615903ae11708b0cb24538c6982abd57fe6fa95b8d3
ToppCellBAL-Severe-Myeloid-Myeloid|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)

COLEC12 DST BRCA1 ANGPTL1 IQGAP3

6.92e-0619461558406502a8cbcc3037f79a1b6a683df408297ae5
ToppCellCOVID-19-Heart-CM_2|Heart / Disease (COVID-19 only), tissue and cell type

AKAP6 DES DST ANK3 MYH7B

7.10e-0619561575fc81bddb246dca3b437fb60827b1d4fe416405
ToppCellfacs-Brain_Myeloid-Hippocampus|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DST MACF1 DDX3Y SCAF11 MAML3

7.10e-06195615a1478021a3ed0e779716393124ca2a7770c433b7
ToppCellmild|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

MACF1 SRSF11 SCAF11 ZFC3H1 GOLGB1

8.02e-0620061512f1685ce8f218433068e090c9d839cd5a1910bf
ToppCell(3)_ILC|World / shred on Cell_type and subtype

DOCK5 DST MAP3K8 DDX3Y NLRP3

8.02e-0620061503554b3f323785b1e0b48fa32de0d92065dd798e
ToppCellBrain_organoid-organoid_Tanaka_cellReport-6m-Neuronal-Intermediate|6m / Sample Type, Dataset, Time_group, and Cell type.

DES DDX3Y SCAF11 ZFC3H1 GOLGB1

8.02e-062006157c261e39ac30b318511373ab7302aa53b8b81b9c
ToppCell(30)_ILC|World / shred on Cell_type and subtype

DOCK5 DST MAP3K8 DDX3Y NLRP3

8.83e-06204615bd9fbd278c05e396463704d711b60d47699e3c09
ToppCellCOVID-19_Mild-PLT_0|COVID-19_Mild / Disease Group and Platelet Clusters

DOCK5 GLYATL2 MACF1 DDX3Y

7.73e-05165614083a14d3b0162cee4e79f7398b8fb739582b39ff
ToppCellPosterior_cortex-Hematopoietic-MICROGLIA-MI2(C1qb)-Tmem119|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

TAGAP SCAF11 IQGAP3 NLRP3

7.92e-05166614063d68f2ffb40770cb4601fa1cb6426ae26f7a37
ToppCellPosterior_cortex-Hematopoietic-MICROGLIA-MI2(C1qb)-Tmem119-MICROGLIA_Microglia.C1qb.Tmem119-Junb_(Microglia)-|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

TAGAP SCAF11 IQGAP3 NLRP3

7.92e-05166614417cfb207da08fa1a0fd5f2a13c8786628667a8e
ToppCellPosterior_cortex-Hematopoietic-MICROGLIA-MI2(C1qb)-Tmem119-MICROGLIA_Microglia.C1qb.Tmem119-Junb_(Microglia)|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

TAGAP SCAF11 IQGAP3 NLRP3

7.92e-05166614f28d07715e6b00ca2a0df39273c5f569744be5a8
ToppCellControl-Lymphoid-ILC_B|Lymphoid / Disease state, Lineage and Cell class

DOCK5 DST MAP3K8 MAML3

8.29e-05168614d7118d39253ed9790908b850088ebfc5a86f4065
ToppCellnormal-na-Lymphocytic_T-T4_em-male|normal / PBMC cell types (v2) per disease, treatment status, and sex

ODF2L ANK3 MACF1 DDX3Y

8.88e-0517161461318a7aaf3bd8bdd28f8a8614ab4fdf2964b3a3
ToppCell356C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_3|CD8+_Cytotoxic_T-cell / Donor, Lineage, Cell class and subclass (all cells)

BRCA1 MYO18A EFHB ZRANB3

9.29e-051736147e2149205e119cec4f5099c83c85d1e13470137a
ToppCellTCGA-Brain-Primary_Tumor-Low_Grade_Glioma|TCGA-Brain / Sample_Type by Project: Shred V9

AKAP6 DST MYO18A GOLGB1

1.01e-04177614e8ab340b20cd41554c3841fe980e078e878af35f
ToppCell3'_v3-Lung-Myeloid_Monocytic-Cycling_mono|Lung / Manually curated celltypes from each tissue

BRCA1 LRRC8D ZRANB3 CCDC144A

1.04e-0417861467aa17b17da3121c199af45e747c23e2626a9bb2
ToppCell3'-Parenchyma_lung-Endothelial-Lymphatic_EC-endothelial_cell_of_lymphatic_vessel-Lymphatic_EC_differentiating-Lymphatic_EC_differentiating_L.2.5.1.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DOCK5 DST GIMAP8 MACF1

1.04e-04178614ad3de3e03a401dac64431a541899445262246347
ToppCellnormal-na-Lymphocytic_NK-T_mait-male|normal / PBMC cell types (v2) per disease, treatment status, and sex

ODF2L MAP3K8 MACF1 DDX3Y

1.08e-04180614e66a8a61b3576ac37de7c559d16d4ed4f7a2fc78
ToppCell10x5'-Liver-Lymphocytic_T_CD4-T_CD4/CD8|Liver / Manually curated celltypes from each tissue

ANK3 OSBPL3 MACF1 DDX3Y

1.11e-04181614f2315414e714ac86211546a935660c4be6e85f1b
ToppCellLV-15._Ventricular_Cardiomyocyte_III|World / Chamber and Cluster_Paper

AKAP6 DES ANK3 MYH7B

1.20e-041856146baccb26f999145e51b91d94315bf8d4655bef31
ToppCell10x5'-bone_marrow-Myeloid_Dendritic-Cycling_Dendritic|bone_marrow / Manually curated celltypes from each tissue

DST BRCA1 HFM1 IQGAP3

1.20e-041856149d3168c7f0b1d739f78b368969cf5c77ce202b97
ToppCellpdx|World / Sample and Cell Type and Tumor Cluster (all cells)

BRCA1 MYH7B MAML3 ZRANB3

1.23e-04186614de8e538c8767d41b8a52f5e58ba1affd4e7244c4
ToppCellpdx-Tumor_cells|World / Sample and Cell Type and Tumor Cluster (all cells)

BRCA1 MYH7B MAML3 ZRANB3

1.23e-041866140b88a87158a9ca8de3bf40a4ff1687150707a5f0
ToppCelldroplet-Liver-HEPATOCYTES-1m-Mesenchymal-hepatic_stellate_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SHROOM4 DES ANK3 CCDC158

1.25e-04187614b6ecf55014f246461bf1ca12f24cb4d046661fa4
ToppCelldroplet-Liver-HEPATOCYTES-1m-Mesenchymal-hepatic_stellate_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SHROOM4 DES ANK3 CCDC158

1.25e-041876149fb15f24b9b364b0c4704ec98aec236eaec5411c
ToppCelldroplet-Liver-HEPATOCYTES-1m-Mesenchymal|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SHROOM4 DES ANK3 CCDC158

1.25e-04187614e6afbaed352310a1cb49571a2aae18be1f533c9a
ToppCelldroplet-Limb_Muscle-nan-3m-Mesenchymal-unknown|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

AKAP6 DES LRGUK HFM1

1.28e-04188614d534ed9870405a3c1075962308f72b460aed17bf
ToppCellAdult-Epithelial-alveolar_epithelial_cell_type_2-D231|Adult / Lineage, Cell type, age group and donor

ARFGEF3 SHROOM4 ANK3 RAI14

1.31e-04189614dab54a52358f66a8a9460cd6089a06c5fa7e7a5d
ToppCellPND10|World / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

HOOK3 DST MACF1 GOLGB1

1.33e-04190614d67e2814047c8df2ae4b7bc8be9539f5df6ecef2
ToppCellRV-06._Ventricular_Cardiomyocyte_II|RV / Chamber and Cluster_Paper

AKAP6 DST ANK3 MYH7B

1.33e-04190614fe8e78922c8ae928ef9a80bffd67868d5a87a091
ToppCellLV-06._Ventricular_Cardiomyocyte_II|LV / Chamber and Cluster_Paper

AKAP6 DST ANK3 MYH7B

1.36e-0419161425f3eb34f4e70761e81e84c8a5829f216108cbc6
ToppCellLA-03._Atrial_Cardiomyocyte|LA / Chamber and Cluster_Paper

AKAP6 DES ANK3 MYH7B

1.36e-041916145d1b674eb7703830b7ce8bbeac3363cabd0e6ae9
ToppCellCD8+_Memory_T_cell-CV-7|CD8+_Memory_T_cell / cell class, Virus stimulation and cluster

UBR1 OSBPL3 CYP51A1 MACF1

1.36e-041916149454f642c3621370fa23640b631301346b300950
ToppCelldroplet-Limb_Muscle-MUSCLE-30m-Mesenchymal-nan|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DES DDX3Y TRIP11 ANGPTL1

1.36e-041916147d1595e616f6f111fc2f5bc1b179c5d67d624cc9
ToppCell10x_5'_v1-Non-neoplastic-Lymphoid-NK|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

BRCA1 TAGAP MCF2 MACF1

1.39e-04192614930319cbd82b9e54864147ffcdc8bd0ea7b937be
ToppCell10x_5'_v1-Non-neoplastic-Lymphoid-NK-NK|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

BRCA1 TAGAP MCF2 MACF1

1.39e-04192614c7bcebcb88a25b2c97d798120efa9d5958e7f798
ToppCellPCW_07-8.5-Mesenchymal-Mesenchymal_fibroblastic-mes_immature4_(1)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

UBR1 CYP51A1 DDX3Y ZFC3H1

1.39e-041926146bba80887d6f64cf913a5c22f62baaddda417ce0
ToppCell10x5'-lymph-node_spleen-Lymphocytic_T_CD4-T_CD4/CD8|lymph-node_spleen / Manually curated celltypes from each tissue

ANK3 MACF1 DDX3Y SRSF11

1.39e-0419261447646d7e4990be85072987f92bf18d52f8da752e
ToppCell10x_3'_v2v3-Non-neoplastic-Glial-Neuronal-Oligodendrocyte-Oligodendrocyte-C|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

ARFGEF3 DST ANK3 CYP51A1

1.39e-041926143ce5dbde41aeb73d49f2c7991d34682f0827fa5a
ToppCelldroplet-Pancreas-Endocrine-21m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DST SRSF11 DPP3 GOLGB1

1.41e-04193614471e65f02937bc18d7c5facdacdf1df58cf0f839
ToppCelldroplet-Pancreas-Endocrine-21m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DST SRSF11 DPP3 GOLGB1

1.41e-04193614fe451b3295d77b2bd1ac25cf29310c85835a45fe
ToppCelldroplet-Pancreas-Endocrine-21m|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DST SRSF11 DPP3 GOLGB1

1.44e-041946143a3ecedcdc7691cf21775818b598208fcb980c29
ToppCelldroplet-Limb_Muscle-MUSCLE|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MACF1 DDX3Y SCAF11 TRIP11

1.44e-04194614e3d63874111d1e8da3977329426e4dcf68d6de87
ToppCelldroplet-Pancreas-Endocrine-21m-Epithelial|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DST SRSF11 DPP3 GOLGB1

1.44e-041946140b023de48ed8a550d169bbe954881eb04bf4f981
ToppCelldroplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DST MACF1 DDX3Y GOLGB1

1.47e-041956143e519cffa6144a62b06124642a14c9ff39b76554
ToppCell10x_5'_v1-Non-neoplastic-Lymphoid-CD4/CD8-Stress_sig-F_2|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

ANK3 TAGAP MACF1 SCAF11

1.50e-04196614ea8eceacc5d5e1a22b77c31e7c45985dc7bb15de
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Glial-Neuronal-Oligodendrocyte-Oligodendrocyte-E|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

ARFGEF3 DST ANK3 DNAH17

1.50e-0419661437a5f9f3988778655580bd0383811bb4930c1551
ToppCellsevere-low-quality_cells|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

ANK3 MACF1 SRSF11 ZFC3H1

1.53e-0419761457ebd552f10d6278623b52a3d484d4b91ae1d028
ToppCell3'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

AKAP6 LRGUK ODF2L OSBPL3

1.53e-0419761474a2c6cb8fcfe53dd9a2b36492a16c58f38e51c9
ToppCell10x_3'_v2v3-Non-neoplastic-Glial-Neuronal-Oligodendrocyte-Oligodendrocyte-B|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

DOCK5 ARFGEF3 DST ANK3

1.53e-0419761482b8e22317cad6d3786bd70d91107007c0ccd7cd
ToppCellParenchymal-NucSeq-Epithelial-Epi_alveolar-AT2|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

ARFGEF3 COLEC12 ANK3 RAI14

1.56e-041986142e2a4e1756bba6f4fbe529559a97d2993c890b4b
ToppCell(11)_FOXN4+-(2)_GFP_FOXI1|(11)_FOXN4+ / shred by cell type by condition

ODF2L SCAF11 TRIP11 GOLGB1

1.56e-0419861476d40b8c2f8399725b3a62ee2ae0896559cf91eb
ToppCell(10)_Ciliated-(2)_GFP_FOXI1|(10)_Ciliated / shred by cell type by condition

ODF2L DDX3Y TRIP11 GOLGB1

1.59e-0419961461b1ed2db71b96157b92b7535d1955a4033098da
ToppCellParenchymal-NucSeq-Epithelial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

DOCK5 ARFGEF3 ANK3 RAI14

1.59e-041996145cea0d9e261903e0eaad60c28a07dff72ce65027
ToppCellcontrol-HLA-DR+_CD83+_Monocyte|control / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

DOCK5 DST GIMAP8 NLRP3

1.59e-04199614f1b370d2869ad29c9d8ff41fdcc486fffa781ee2
ToppCellmLN-ILC-ILC|mLN / Region, Cell class and subclass

DOCK5 DST MAP3K8 NLRP3

1.59e-04199614ab09a06cdea2597e9fe4b4b304655e9de4d433f6
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Glial-Neuronal-Oligodendrocyte-Oligodendrocyte-G|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

DOCK5 ARFGEF3 DST ANK3

1.59e-04199614214a6a267e77e5508867b9eb48c4fbc7855ed0a0
ToppCellmLN-ILC|mLN / Region, Cell class and subclass

DOCK5 DST MAP3K8 NLRP3

1.59e-04199614d6c299312c747fb1b7c53644c53efc03a5fffe85
ToppCellmLN-(3)_ILC|mLN / shred on region, Cell_type, and subtype

DOCK5 DST MAP3K8 NLRP3

1.59e-0419961400e0e2a766dd9c4d0a65f53d88fa50df4b6a3d60
ToppCell(03)_KRT6B+-(2)_GFP_FOXI1|(03)_KRT6B+ / shred by cell type by condition

DST USP25 TRIP11 GOLGB1

1.59e-04199614c425e7975f492ed5cfcca022248adb627e1d27d4
ToppCellLPS_IL1RA_TNF-Mesenchymal_fibroblastic-Fibroblasts-Activated_MatrixFB|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

COLEC12 DES DST MACF1

1.59e-04199614e1849505b92820a219c5a2c35492bdd55579fb48
ToppCellmLN-(3)_ILC-(30)_ILC|mLN / shred on region, Cell_type, and subtype

DOCK5 DST MAP3K8 NLRP3

1.59e-0419961433ac6d77099076df01299be429f4ba96f2f34cc1
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Glial-Neuronal|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

DOCK5 ARFGEF3 DST ANK3

1.62e-04200614acdef0b9096c774040948fc75621ff2b08ea2ee8
ComputationalGenes upregulated in subsets of cells of a given type within various tumors

DST MACF1 TRIP11 GOLGB1

1.19e-0550314GAVISH_3CA_MALIGNANT_METAPROGRAM_4_CHROMATIN
ComputationalGenes upregulated in subsets of cells of a given type within various tumors

DST MACF1 GOLGB1

3.88e-0450313GAVISH_3CA_METAPROGRAM_FIBROBLASTS_CAF_4
DiseaseMalignant neoplasm of breast

AKAP6 ZNF438 DES HOOK3 BRCA1 INPP5K MACF1 TRAPPC8 GOLGB1

2.03e-041074579C0006142
Diseaseunipolar depression, bipolar disorder

COLEC12 ANK3 CCDC73 OSBPL3

2.39e-04156574EFO_0003761, MONDO_0004985
DiseaseC-reactive protein measurement

AKAP6 ANK3 MAP3K8 DNAH17 MACF1 HFM1 SCAF11 MAML3 NLRP3

4.74e-041206579EFO_0004458
Diseaseresponse to corticosteroid

DST ANK3

1.44e-0329572GO_0031960

Protein segments in the cluster

PeptideGeneStartEntry
DNSLELSQLENKILN

ANGPTL1

146

O95841
SEADQQDLLSLLQAK

RAI14

341

Q9P0K7
EKINFENANLSALNL

ODF2L

76

Q9ULJ1
ENANLSALNLKISEQ

ODF2L

81

Q9ULJ1
SLQDDSKNENLLDLN

KIAA0100

1841

Q14667
SLSNQNKLFSDINLN

MAML3

291

Q96JK9
DNQESLDNNLEALKN

DST

3416

Q03001
QDSNQNDERSKSLLL

MAP3K8

51

P41279
LALQLQAEQDNLADA

MYH7B

936

A7E2Y1
LEAANQSLQADLKLA

MYO18A

1911

Q92614
NNSALAKANNDTLED

COLEC12

271

Q5KU26
AKLAQDFLDSQNLSA

DPP3

181

Q9NY33
DLSAANEKNLLLQNQ

LRRC45

361

Q96CN5
LEDLKALQNLDLSHN

LRGUK

276

Q96M69
NEKIALLQSLLDDAN

HOOK3

486

Q86VS8
LEAKNASLASSNNDL

GOLGA3

491

Q08378
LNQSQQDFLAEAELL

IQGAP3

861

Q86VI3
NDLENLNSDTFSLLK

LRRC70

286

Q7Z2Q7
ALQKNQSDLKDLQDD

MACF1

3651

Q9UPN3
QELCLKNLNDLSSLD

HFM1

751

A2PYH4
TEENLLSLKNSLNDC

BRCA1

1256

P38398
LLTDQLSGQLDDNSN

DOCK5

881

Q9H7D0
AQEALDTLNKNNLTE

DNAH17

3136

Q9UFH2
TDSDEKQLLNQILNA

ARFGEF3

86

Q5TH69
DLSDLLQLNNRNLNL

INPP5K

31

Q9BT40
NQLNKSENLLSLEND

CCDC73

1046

Q6ZRK6
ALLFNSKNEDLNAED

CYP51A1

121

Q16850
SDLTQAANKNNDALR

DES

301

P17661
DQDLDTFLRNSNKAL

GIMAP8

371

Q8ND71
KAAALLLQNDNNADV

ANK3

216

Q12955
LENLDENSQELLSKA

MCF2

261

P10911
DQANLSLDDKLLDQL

EFHB

591

Q8N7U6
ESGNLDDQLQKLLAD

CCDC158

371

Q5M9N0
NNLTAENKILNSELE

CCDC144A

886

A2RUR9
ELDQQLANLDLNSEK

DDX3Y

11

O15523
QDSENNLLKNNLLNT

SCAF11

661

Q99590
QLKDCSNLQDQADIL

PHKA2

766

P46019
SLSNLQELDLKSNNI

LRRC8D

656

Q7L1W4
NLSLDNLSNDLDNER

OSBPL3

481

Q9H4L5
SSLLLDDAQNQNQPK

PRR14L

1421

Q5THK1
SNQKLVELDLSDNAL

NLRP3

796

Q96P20
NNLEAALNVLLTSNK

TDRD3

221

Q9H7E2
QNLDCLNSDLEKDLQ

TMCO5B

26

A8MYB1
NDQSLSFEAQKDLNN

TAGAP

246

Q8N103
NSLGNLAKSLDAEQD

SPATA31A6

361

Q5VVP1
DQLKKDLESANLTAN

POT1

286

Q9NUX5
NALNSIDSEANQEKL

SHROOM4

1391

Q9ULL8
NKLISLNEESNDLDQ

AKAP6

1226

Q13023
NSLRNLAKSLDAEQD

SPATA31A3

361

Q5VYP0
NSLRNLAKSLDAEQD

SPATA31A1

361

Q5TZJ5
NLNSQSLAADQLLKL

SRSF11

176

Q05519
NSLRNLAKSLDAEQD

SPATA31A5

361

Q5VU36
SSAELEDQNKLLLNE

SOGA1

291

O94964
LQQALKDSNGNLELA

USP25

36

Q9UHP3
QKINSENADALAQLL

UBR1

1216

Q8IWV7
ALQDQLLKLQSAAQS

TRIP11

116

Q15643
SLNQDNSLAEDNLKL

TRIP11

406

Q15643
KNSDNNLLSLDGLDN

TRAPPC8

271

Q9Y2L5
LTKNLELNDDTILND

TTC27

311

Q6P3X3
ENKSNLEEDFLLNQA

ZNF438

626

Q7Z4V0
SALAILQNALKSAND

ZFC3H1

1496

O60293
ENLINALNKSGLSDL

THOC1

631

Q96FV9
TADAKTLIDALNNQN

ZRANB3

136

Q5FWF4
ADNNEKSLQALNNLG

GLYATL2

261

Q8WU03
DLNSENAKLDAELIQ

GOLGB1

2521

Q14789