Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	alpha-tubulin binding	DIP2B ARL8B ARL8A DYSF	1.09e-05	52	53	4	GO:0043014
GeneOntologyMolecularFunction	dihydropyrimidinase activity	DPYSL2 CRMP1	1.03e-04	6	53	2	GO:0004157
GeneOntologyMolecularFunction	cytoskeletal protein binding	DIP2B FLNA MISP ARL8B CAPZA1 APBB1 ARL8A DYSF CRMP1 MYO5C MYBPC1	1.20e-04	1099	53	11	GO:0008092
Domain	Hydantoinase/dihydroPyrase	DPYSL2 CRMP1	1.18e-04	6	53	2	IPR011778
Domain	-	DPYSL2 CRMP1	2.19e-04	8	53	2	2.30.40.10
Domain	Amidohydro_1	DPYSL2 CRMP1	3.50e-04	10	53	2	PF01979
Domain	Metal-dep_hydrolase_composite	DPYSL2 CRMP1	3.50e-04	10	53	2	IPR011059
Domain	Amidohydro-rel	DPYSL2 CRMP1	4.27e-04	11	53	2	IPR006680
Domain	GST_N	GSTT2 GSTT2B	1.76e-03	22	53	2	PF02798
Domain	GST_NTER	GSTT2 GSTT2B	1.76e-03	22	53	2	PS50404
Domain	Metal_Hydrolase	DPYSL2 CRMP1	2.10e-03	24	53	2	IPR032466
Domain	GST_C	GSTT2 GSTT2B	2.46e-03	26	53	2	IPR004046
Domain	GST_C	GSTT2 GSTT2B	2.46e-03	26	53	2	PF00043
Domain	Glutathione_S-Trfase_N	GSTT2 GSTT2B	2.65e-03	27	53	2	IPR004045
Domain	ARF	ARL8B ARL8A	3.05e-03	29	53	2	PS51417
Domain	Small_GTPase_ARF	ARL8B ARL8A	3.05e-03	29	53	2	IPR024156
Domain	AMP-binding	DIP2B ACSM4	3.27e-03	30	53	2	PF00501
Domain	AMP-dep_Synth/Lig	DIP2B ACSM4	3.27e-03	30	53	2	IPR000873
Domain	Arf	ARL8B ARL8A	3.49e-03	31	53	2	PF00025
Domain	Small_GTPase_ARF/SAR	ARL8B ARL8A	3.94e-03	33	53	2	IPR006689
Domain	GST_CTER	GSTT2 GSTT2B	4.18e-03	34	53	2	PS50405
Domain	DNA/RNA_helicase_DEAH_CS	CHD8 DHX30	4.43e-03	35	53	2	IPR002464
Domain	DEAH_ATP_HELICASE	CHD8 DHX30	5.20e-03	38	53	2	PS00690
Domain	Glutathione-S-Trfase_C-like	GSTT2 GSTT2B	5.47e-03	39	53	2	IPR010987
Domain	-	GSTT2 GSTT2B	5.47e-03	39	53	2	1.20.1050.10
Pubmed	Unbiased Profiling of the Human Proinsulin Biosynthetic Interaction Network Reveals a Role for Peroxiredoxin 4 in Proinsulin Folding.	TDRD7 FLNA ABCD3 PLEKHA1 CHD8 ARL8A CRMP1 DHX30	4.95e-07	464	53	8	32457219
Pubmed	Drosophila Topors is a RING finger-containing protein that functions as a ubiquitin-protein isopeptide ligase for the hairy basic helix-loop-helix repressor protein.	ARL8B ARL8A	2.28e-06	2	53	2	14871887
Pubmed	Phosphorylation of CRMP2 (collapsin response mediator protein 2) is involved in proper dendritic field organization.	DPYSL2 CRMP1	2.28e-06	2	53	2	22279220
Pubmed	Gene structure, expression and chromosomal localization of murine theta class glutathione transferase mGSTT1-1.	GSTT2 GSTT2B	2.28e-06	2	53	2	9854036
Pubmed	Sauchinone controls hepatic cholesterol homeostasis by the negative regulation of PCSK9 transcriptional network.	SREBF2 PCSK9	2.28e-06	2	53	2	29712938
Pubmed	Loss of CRMP1 and CRMP2 results in migration defects of Purkinje cells in the X lobule of the mouse cerebellum.	DPYSL2 CRMP1	2.28e-06	2	53	2	35219721
Pubmed	Identification and characterization of GSTT3, a third murine Theta class glutathione transferase.	GSTT2 GSTT2B	2.28e-06	2	53	2	12038961
Pubmed	Linkage disequilibrium between two high-frequency deletion polymorphisms: implications for association studies involving the glutathione-S transferase (GST) genes.	GSTT2 GSTT2B	2.28e-06	2	53	2	19424424
Pubmed	An N-terminally acetylated Arf-like GTPase is localised to lysosomes and affects their motility.	ARL8B ARL8A	2.28e-06	2	53	2	16537643
Pubmed	Presynaptic Biogenesis Requires Axonal Transport of Lysosome-Related Vesicles.	ARL8B ARL8A	2.28e-06	2	53	2	30174114
Pubmed	Mammalian class theta GST and differential susceptibility to carcinogens: a review.	GSTT2 GSTT2B	2.28e-06	2	53	2	11018744
Pubmed	Characterization of a cDNA and gene encoding the mouse theta class glutathione transferase mGSTT2 and its localization to chromosome 10B5-C1.	GSTT2 GSTT2B	2.28e-06	2	53	2	8617493
Pubmed	Characterization of a human class-Theta glutathione S-transferase with activity towards 1-menaphthyl sulphate.	GSTT2 GSTT2B	2.28e-06	2	53	2	1417752
Pubmed	Molecular cloning of a cDNA and chromosomal localization of a human theta-class glutathione S-transferase gene (GSTT2) to chromosome 22.	GSTT2 GSTT2B	2.28e-06	2	53	2	7789971
Pubmed	Phosphorylation of CRMP2 is required for migration and positioning of Purkinje cells: Redundant roles of CRMP1 and CRMP4.	DPYSL2 CRMP1	6.83e-06	3	53	2	32156571
Pubmed	Expression of collapsin response mediator proteins 1, 2 and 5 is differentially regulated in newly generated and mature neurons of the adult olfactory system.	DPYSL2 CRMP1	6.83e-06	3	53	2	15926912
Pubmed	The distribution of theta-class glutathione S-transferases in the liver and lung of mouse, rat and human.	GSTT2 GSTT2B	6.83e-06	3	53	2	8761485
Pubmed	Glutathione S-transferases promote proinflammatory astrocyte-microglia communication during brain inflammation.	GSTT2 GSTT2B	6.83e-06	3	53	2	30783009
Pubmed	Spire1 and Myosin Vc promote Ca2+-evoked externalization of von Willebrand factor in endothelial cells.	VWF MYO5C	6.83e-06	3	53	2	35084586
Pubmed	CRMP1 and CRMP2 have synergistic but distinct roles in dendritic development.	DPYSL2 CRMP1	6.83e-06	3	53	2	27480924
Pubmed	Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.	TRPM6 FLNA ERLIN2 CAPZA1 ABCD3 CPSF1 NASP ARL8A DNTTIP2 DHX30 MYBPC1	8.21e-06	1425	53	11	30948266
Pubmed	The Ulip family phosphoproteins--common and specific properties.	DPYSL2 CRMP1	1.36e-05	4	53	2	9652388
Pubmed	Novel small GTPase subfamily capable of associating with tubulin is required for chromosome segregation.	ARL8B ARL8A	1.36e-05	4	53	2	15331635
Pubmed	Identification, characterization, and crystal structure of the Omega class glutathione transferases.	GSTT2 GSTT2B	1.36e-05	4	53	2	10783391
Pubmed	Amino- and carboxyl-terminal domains of Filamin-A interact with CRMP1 to mediate Sema3A signalling.	FLNA CRMP1	1.36e-05	4	53	2	25358863
Pubmed	Hepatic overexpression of idol increases circulating protein convertase subtilisin/kexin type 9 in mice and hamsters via dual mechanisms: sterol regulatory element-binding protein 2 and low-density lipoprotein receptor-dependent pathways.	SREBF2 PCSK9	1.36e-05	4	53	2	24675665
Pubmed	Differential expression of dihydropyrimidinase-related protein genes in developing and adult enteric nervous system.	DPYSL2 CRMP1	1.36e-05	4	53	2	10664068
Pubmed	A functional coupling between CRMP1 and Nav1.7 for retrograde propagation of Semaphorin3A signaling.	DPYSL2 CRMP1	1.36e-05	4	53	2	28254884
Pubmed	HSF1 phosphorylation establishes an active chromatin state via the TRRAP-TIP60 complex and promotes tumorigenesis.	FLNA MISP CAPZA1 ABCD3 CPSF1 NASP DNTTIP2 CRMP1	1.76e-05	754	53	8	35906200
Pubmed	SRCAP complex promotes lung cancer progression by reprograming the oncogenic transcription of Hippo-YAP/TAZ signaling pathway.	FLNA DPYSL2 CAPZA1 APBB1 NASP CHD8 TFAP2A	1.93e-05	549	53	7	38280479
Pubmed	Structure and organization of the human theta-class glutathione S-transferase and D-dopachrome tautomerase gene complex.	GSTT2 GSTT2B	2.27e-05	5	53	2	9729470
Pubmed	The novel function of HINFP as a co-activator in sterol-regulated transcription of PCSK9 in HepG2 cells.	SREBF2 PCSK9	2.27e-05	5	53	2	22288532
Pubmed	Distinct priming kinases contribute to differential regulation of collapsin response mediator proteins by glycogen synthase kinase-3 in vivo.	DPYSL2 CRMP1	2.27e-05	5	53	2	16611631
Pubmed	p80 ROKalpha binding protein is a novel splice variant of CRMP-1 which associates with CRMP-2 and modulates RhoA-induced neuronal morphology.	DPYSL2 CRMP1	2.27e-05	5	53	2	12482610
Pubmed	A novel gene family defined by human dihydropyrimidinase and three related proteins with differential tissue distribution.	DPYSL2 CRMP1	2.27e-05	5	53	2	8973361
Pubmed	Differential expression of CRMP1, CRMP2A, CRMP2B, and CRMP5 in axons or dendrites of distinct neurons in the mouse brain.	DPYSL2 CRMP1	2.27e-05	5	53	2	15834957
Pubmed	The Catalytically Inactive Mutation of the Ubiquitin-Conjugating Enzyme CDC34 Affects its Stability and Cell Proliferation.	DIP2B ARL8B ABCD3 CPSF1 ARL8A	3.10e-05	237	53	5	29564676
Pubmed	Molecular characterization of CRMP5, a novel member of the collapsin response mediator protein family.	DPYSL2 CRMP1	3.40e-05	6	53	2	10956643
Pubmed	Erlins restrict SREBP activation in the ER and regulate cellular cholesterol homeostasis.	ERLIN2 SREBF2	4.76e-05	7	53	2	24217618
Pubmed	KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.	FLNA MISP DPYSL2 ERLIN2 VWF TTC21A CAPZA1 ABCD3 CRMP1 DHX30	5.22e-05	1431	53	10	37142655
Pubmed	Hypertonicity-responsive ubiquitin ligase RNF183 promotes Na, K-ATPase lysosomal degradation through ubiquitination of its β1 subunit.	FLNA ERLIN2 CAPZA1 ABCD3 APBB1 NASP	6.15e-05	449	53	6	31732153
Pubmed	ZZW-115-dependent inhibition of NUPR1 nuclear translocation sensitizes cancer cells to genotoxic agents.	FLNA MISP ERLIN2 CAPZA1 CPSF1 DNTTIP2 DHX30	6.21e-05	660	53	7	32780723
Pubmed	Gene expression profiling in human skeletal muscle during recovery from eccentric exercise.	CAPZA1 SREBF2	6.34e-05	8	53	2	18321953
Pubmed	CRMP-2 binds to tubulin heterodimers to promote microtubule assembly.	DPYSL2 CRMP1	6.34e-05	8	53	2	12134159
Pubmed	ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1.	DPYSL2 NPTX1 CCPG1 ERLIN2 MANBA CPSF1 FKBP11 ATF6B PCSK9	7.64e-05	1201	53	9	35696571
Pubmed	N-Terminal Acetyltransferase Naa40p Whereabouts Put into N-Terminal Proteoform Perspective.	FLNA DPYSL2 CAPZA1 ABCD3 APBB1 NASP DNTTIP2 DHX30	7.98e-05	934	53	8	33916271
Pubmed	CRMP2 mediates Sema3F-dependent axon pruning and dendritic spine remodeling.	DPYSL2 CRMP1	8.15e-05	9	53	2	31919978
Pubmed	The mouse poly(C)-binding protein exists in multiple isoforms and interacts with several RNA-binding proteins.	FLNA YBX2	8.15e-05	9	53	2	8871564
Pubmed	A generic approach for the purification of signaling complexes that specifically interact with the carboxyl-terminal domain of G protein-coupled receptors.	TRPM6 DPYSL2 CRMP1	8.29e-05	55	53	3	18448421
Pubmed	TBK1 phosphorylation activates LIR-dependent degradation of the inflammation repressor TNIP1.	FLNA MISP CAPZA1 CPSF1 TFAP2A DNTTIP2 MYO5C DHX30	8.91e-05	949	53	8	36574265
Pubmed	A Degradation Motif in STAU1 Defines a Novel Family of Proteins Involved in Inflammation.	AVEN FLNA DPYSL2 ERLIN2 CAPZA1 DYSF TFAP2A	1.10e-04	724	53	7	36232890
Pubmed	C5orf51 is a component of the MON1-CCZ1 complex and controls RAB7A localization and stability during mitophagy.	COG6 ABCD3 SREBF2 APBB1 PLEKHA1 ATF6B	1.16e-04	504	53	6	34432599
Pubmed	Fine genetic and comparative mapping of the deafness mutation Ames waltzer on mouse chromosome 10.	GSTT2 GSTT2B	1.24e-04	11	53	2	9653653
Pubmed	Protein interactome mining defines melatonin MT1 receptors as integral component of presynaptic protein complexes of neurons.	FLNA DPYSL2 SREBF2 NASP CRMP1	1.31e-04	322	53	5	26514267
Pubmed	Defining human ERAD networks through an integrative mapping strategy.	DIP2B FLNA ERLIN2 ABCD3	1.43e-04	173	53	4	22119785
Pubmed	Host E3 ligase HUWE1 attenuates the proapoptotic activity of the MERS-CoV accessory protein ORF3 by promoting its ubiquitin-dependent degradation.	FLNA DPYSL2 ERLIN2 CPSF1 CHD8 DHX30	1.59e-04	534	53	6	35032548
Pubmed	Defining the proximal interaction networks of Arf GTPases reveals a mechanism for the regulation of PLD1 and PI4KB.	AVEN ERLIN2 ARL8B LIN54 ABCD3 APBB1 ARL8A	1.71e-04	777	53	7	35844135
Pubmed	BORC, a multisubunit complex that regulates lysosome positioning.	ARL8B ARL8A	1.76e-04	13	53	2	25898167
Pubmed	The Rab7 effector PLEKHM1 binds Arl8b to promote cargo traffic to lysosomes.	ARL8B ARL8A	1.76e-04	13	53	2	28325809
Pubmed	The ubiquitin E3 ligase ARIH1 regulates hnRNP E1 protein stability, EMT and breast cancer progression.	FLNA DPYSL2 CAPZA1	2.01e-04	74	53	3	35102251
Pubmed	Genetic factors in nonsmokers with age-related macular degeneration revealed through genome-wide gene-environment interaction analysis.	PLEKHA1 ATF6B	2.05e-04	14	53	2	23577725
Pubmed	MECP2 directly interacts with RNA polymerase II to modulate transcription in human neurons.	DIP2B DPYSL2 NPTX1 ABCD3 CPSF1 FKBP11 CRMP1 DHX30	2.19e-04	1082	53	8	38697112
Pubmed	N-Terminomics for the Identification of In Vitro Substrates and Cleavage Site Specificity of the SARS-CoV-2 Main Protease.	FLNA DPYSL2 VWF COG6 APBB1	2.21e-04	360	53	5	33111431
Pubmed	Nucleolar protein trafficking in response to HIV-1 Tat: rewiring the nucleolus.	FLNA DPYSL2 ARL8B	2.26e-04	77	53	3	23166591
Pubmed	Combinatorial targeting of a chromatin complex comprising Dot1L, menin and the tyrosine kinase BAZ1B reveals a new therapeutic vulnerability of endocrine therapy-resistant breast cancer.	CCPG1 ERLIN2 CAPZA1 CPSF1 TFAP2A DNTTIP2 DHX30	2.88e-04	847	53	7	35850772
Pubmed	In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.	FLNA YBX2 ERLIN2 ARL8B LIN54 CAPZA1 ARL8A DNTTIP2 MYBPC1	3.01e-04	1442	53	9	35575683
Pubmed	Prediction of the coding sequences of mouse homologues of FLJ genes: the complete nucleotide sequences of 110 mouse FLJ-homologous cDnas identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	FLNA DYSF GPAT2	3.02e-04	85	53	3	15449545
Pubmed	Irisin Mediates Effects on Bone and Fat via αV Integrin Receptors.	FLNA DPYSL2 ERLIN2 ARL8B TTC21A ABCD3 CPSF1 CHD8 FKBP11	3.15e-04	1451	53	9	30550785
Pubmed	A trimeric Rab7 GEF controls NPC1-dependent lysosomal cholesterol export.	MISP ERLIN2 ARL8B CAPZA1 ARL8A	3.26e-04	392	53	5	33144569
Pubmed	Deciphering gene expression program of MAP3K1 in mouse eyelid morphogenesis.	TFAP2A MYBPC1	3.83e-04	19	53	2	23201579
Pubmed	Integrative predictive model of coronary artery calcification in atherosclerosis.	VWF SREBF2 PLEKHA1 PCSK9	4.16e-04	229	53	4	19948975
Pubmed	Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.	FLNA DPYSL2 CPSF1 CHD8 DNTTIP2 DHX30	4.65e-04	653	53	6	22586326
Pubmed	Genome-wide, large-scale production of mutant mice by ENU mutagenesis.	TDRD7 TFAP2A	5.16e-04	22	53	2	10932192
Pubmed	Extracellular matrix secretion by cardiac fibroblasts: role of microRNA-29b and microRNA-30c.	SRPX2 VWF ATF6B PCSK9	5.62e-04	248	53	4	24006456
Pubmed	Perinatal deiodinase 2 expression in hepatocytes defines epigenetic susceptibility to liver steatosis and obesity.	SREBF2 PCSK9	5.65e-04	23	53	2	26508642
Pubmed	TWIST1 and chromatin regulatory proteins interact to guide neural crest cell differentiation.	LIN54 CHD8 DHX30	6.26e-04	109	53	3	33554859
Pubmed	Parkinson's disease-associated LRRK2-G2019S mutant acts through regulation of SERCA activity to control ER stress in astrocytes.	ARL8B CAPZA1 NASP DHX30	6.42e-04	257	53	4	31046837
Pubmed	ISG15 Connects Autophagy and IFN-γ-Dependent Control of Toxoplasma gondii Infection in Human Cells.	FLNA MISP MYO5C DHX30	7.50e-04	268	53	4	33024031
Pubmed	A novel role for the peptidyl-prolyl cis-trans isomerase Cyclophilin A in DNA-repair following replication fork stalling via the MRE11-RAD50-NBS1 complex.	MISP ABCD3 APBB1 CHD8 CRMP1	7.57e-04	472	53	5	38943005
Pubmed	Comparison of an expanded ataxia interactome with patient medical records reveals a relationship between macular degeneration and ataxia.	VWF COG6 CRMP1	7.88e-04	118	53	3	21078624
Pubmed	Endocytic recycling protein EHD1 regulates primary cilia morphogenesis and SHH signaling during neural tube development.	DYSF TFAP2A	8.40e-04	28	53	2	26884322
Pubmed	Large-scale proteomics and phosphoproteomics of urinary exosomes.	FLNA VWF ARL8B CAPZA1 PLEKHA1 ARL8A DYSF	8.50e-04	1016	53	7	19056867
Pubmed	Inhibition of calpain 1 restores plasma membrane stability to pharmacologically rescued Phe508del-CFTR variant.	FLNA YBX2 MISP ERLIN2 CAPZA1	8.78e-04	488	53	5	31324722
Pubmed	Identifying biological pathways that underlie primordial short stature using network analysis.	FLNA CAPZA1 ABCD3 CPSF1 DNTTIP2 MYO5C DHX30	8.90e-04	1024	53	7	24711643
Pubmed	Raftlin is involved in the nucleocapture complex to induce poly(I:C)-mediated TLR3 activation.	RFTN2 DHX30	9.01e-04	29	53	2	21266579
Pubmed	Analysis of lipid pathway genes indicates association of sequence variation near SREBF1/TOM1L2/ATPAF2 with dementia risk.	SREBF2 PCSK9	9.01e-04	29	53	2	20167577
Pubmed	Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.	FLNA DPYSL2 CAPZA1 ABCD3 CPSF1 CHD8 DNTTIP2 DHX30	9.59e-04	1353	53	8	29467282
Pubmed	The functional interactome landscape of the human histone deacetylase family.	YBX2 ERLIN2 CPSF1 DNTTIP2	9.93e-04	289	53	4	23752268
Pubmed	HIV-1 Vpr degrades the HLTF DNA translocase in T cells and macrophages.	FLNA MISP	1.10e-03	32	53	2	27114546
Pubmed	Biological insights from 108 schizophrenia-associated genetic loci.	KCNB1 SREBF2 SRR RFTN2	1.18e-03	303	53	4	25056061
Pubmed	Landscape of the SOX2 protein-protein interactome.	FLNA CAPZA1 DHX30	1.19e-03	136	53	3	21280222
Pubmed	Characterization of the piRNA complex from rat testes.	GSTT2 ZDHHC23 GSTT2B	1.29e-03	140	53	3	16778019
Pubmed	mTORC2 interactome and localization determine aggressiveness of high-grade glioma cells through association with gelsolin.	FLNA DPYSL2 ERLIN2 ARL8B	1.32e-03	312	53	4	37120454
Pubmed	The gluconeogenic enzyme PCK1 phosphorylates INSIG1/2 for lipogenesis.	FLNA ERLIN2 SREBF2	1.32e-03	141	53	3	32322062
Pubmed	Comparative interactome analysis of α-arrestin families in human and Drosophila.	ERLIN2 ABCD3 CPSF1 DHX30	1.33e-03	313	53	4	38270169
Pubmed	Comparative Multiplexed Interactomics of SARS-CoV-2 and Homologous Coronavirus Nonstructural Proteins Identifies Unique and Shared Host-Cell Dependencies.	CCPG1 ERLIN2	1.39e-03	36	53	2	33263384
Pubmed	Loss of ER retention motif of AGR2 can impact mTORC signaling and promote cancer metastasis.	FLNA CCPG1 CLEC4F ERLIN2 ARL8B CHD8	1.39e-03	807	53	6	30575818
Pubmed	Comparative analysis of virus-host interactomes with a mammalian high-throughput protein complementation assay based on Gaussia princeps luciferase.	FLNA CHD8 TFAP2A	1.51e-03	148	53	3	22898364
Interaction	INS interactions	TDRD7 FLNA ZDHHC23 ABCD3 PLEKHA1 CHD8 ARL8A CRMP1 DHX30	7.52e-06	519	53	9	int:INS
Cytoband	7q31.32	RNF133 IQUB	1.01e-04	13	53	2	7q31.32
Cytoband	2p13.3	CLEC4F DYSF	8.03e-04	36	53	2	2p13.3
Cytoband	12q13.12	DIP2B FKBP11	8.95e-04	38	53	2	12q13.12
Cytoband	22q11.23	GSTT2 GSTT2B	1.74e-03	53	53	2	22q11.23
GeneFamily	Glutathione S-transferases	GSTT2 GSTT2B	1.06e-03	25	35	2	567
GeneFamily	Ring finger proteins\|Tripartite motif containing\|ARF GTPase family	ARL8B ARL8A	1.63e-03	31	35	2	357
GeneFamily	Tetratricopeptide repeat domain containing\|Bardet-Biedl syndrome associated\|BBSome	TTC21A NASP	2.08e-02	115	35	2	769
ToppCell	facs-Brain_Myeloid-Cortex-24m-Myeloid-microglial_cell\|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MISP CLEC4F VWF KCNB1 CDH17	2.32e-06	179	53	5	0cef6d2eab2015cac0dd340532b24bfec9707330
Computational	Developmental processes.	FLNA DPYSL2 NPTX1 NRG2 TFAP2A CRMP1 MYBPC1	4.44e-05	333	32	7	MODULE_220
Disease	Charcot-Marie-Tooth disease (biomarker_via_orthology)	GSTT2 GSTT2B	2.93e-06	2	51	2	DOID:10595 (biomarker_via_orthology)
Disease	3-formylindole measurement	GSTT2 GSTT2B	2.26e-04	13	51	2	EFO_0801025
Disease	Varicose veins	DIP2B DPYSL2 COG6 MYBPC1	3.49e-04	193	51	4	HP_0002619
Disease	Hypercholesterolemia, Familial	SREBF2 PCSK9	4.40e-04	18	51	2	C0020445
Disease	level of Sphingomyelin (d38:1) in blood serum	SLC52A1 PCSK9	1.24e-03	30	51	2	OBA_2045180
Disease	level of Sphingomyelin (d40:1) in blood serum	SLC52A1 PCSK9	1.41e-03	32	51	2	OBA_2045182
Disease	Huntington's disease (implicated_via_orthology)	YBX2 FKBP11	1.41e-03	32	51	2	DOID:12858 (implicated_via_orthology)

Protein segments in the cluster

Peptide	Gene	Start	Entry
GQRLSVPVKVVLQPQ	CHD8	391	Q9HCK8
ITPPTAQVVGVLKIQ	CAPZA1	181	P52907
GINIPDQTVIKKGPV	TFAP2A	166	P05549
VQIIDENGNVLPPGK	ACSM4	401	P0C7M7
VPVAKPVGVDVINGA	APBB1	551	O00213
GLQLIVVILPGKTPV	AGO4	506	Q9HCK5
IFQQPPVGVRKIVLA	DHX30	716	Q7L2E3
VGAIHPVIQPVGQRK	RFTN2	76	Q52LD8
PIKPQGVLVLGQEQD	NPTX1	346	Q15818
DKPQLQGIPVLVLGN	ARL8B	116	Q9NVJ2
DKPQLQGIPVLVLGN	ARL8A	116	Q96BM9
NGHVVPIKPQVKGVV	MISP	241	Q8IVT2
AKLPPQQIKVVTIGG	LIN54	176	Q6MZP7
LIKQIGENLIVPGGV	DPYSL2	41	Q16555
TQALAVPKPIGGVVV	CPSF1	266	Q10570
IRKSQLVQPVGPLVV	PCSK9	271	Q8NBP7
KAPVVVEGKVQGLVP	NRG2	126	O14511
GKILPGVKVVIVNPE	DIP2B	1366	Q9P265
VQVLGPLIGVQVPEE	GSTT2B	116	P0CG30
GKAVLEQLVGQEVPP	NASP	326	P49321
PGLVIQAVRVTKPNI	ERLIN2	161	O94905
PLKVRIEQVIVAEPG	COG6	356	Q9Y2V7
PPKLEEIGNQEVVIV	CCPG1	111	Q9ULG6
DPLVIELGQKQVIPG	FKBP11	81	Q9NYL4
GVLVIALPIPIIVNN	KCNB1	401	Q14721
ELVQGTVPLEVPQVK	AVEN	201	Q9NQS1
KVQGPKGLVEPVDVV	FLNA	1486	P21333
VQVLGPLIGVQVPKE	GSTT2	116	P0CG29
QVGIVPDALLVPVAV	GPAT2	316	Q6NUI2
PVGGQVIVAIPKLQT	MANBA	246	O00462
VLIPVGQEIVIPFKV	IQUB	136	Q8NA54
ANGIIVEGPVPITIK	CDH17	101	Q12864
VIEGRQLPGVNIKPV	DYSF	226	O75923
LIKQIGENLIVPGGV	CRMP1	41	Q14194
VIKPQVINQAVGLPA	FEZF2	151	Q8TBJ5
VAGVIVPPEGKIQNA	RNF133	71	Q8WVZ7
LNQVPLVDALVVPVG	SRR	171	Q9GZT4
PKITPVQAVNVGQLL	TDRD7	506	Q8NHU6
KGIEGVQVIPLIPGA	ABCD3	416	P28288
VQVIPLIPGAGEIII	ABCD3	421	P28288
VVLIQGAIRVQPEGP	ATF6B	281	Q99941
PVPKPVQAVILGDNI	CLEC4F	66	Q8N1N0
IVPGNEKQIVGTPVN	DNTTIP2	221	Q5QJE6
VAVVVPVPAGEPQKG	YBX2	26	Q9Y2T7
VPVVGLVVEGGPNVI	TRPM6	286	Q9BX84
IKRLPGDIQVVPIGV	VWF	1616	P04275
LAPGKGEQVPIQVVQ	SLC52A1	71	Q9NWF4
VTIIELVGQPPQEVG	SRPX2	376	O60687
VPIKQVPGGVKQLEP	SREBF2	311	Q12772
PGQIVSPLLKQVAVI	TTC21A	476	Q8NDW8
FLQEVVPKGRVGPVQ	ZDHHC23	156	Q8IYP9
VGGVPIITPTQKEEV	PLEKHA1	146	Q9HB21
IIIMEKNIQPIIVPG	MYO5C	1501	Q9NQX4
IQIIDRPGPPQIVKI	MYBPC1	926	Q00872