| Category | Name | IntersectionWithQuery | PValue | GenesInTerm | GenesInQuery | GenesInTermInQuery | ID |
|---|---|---|---|---|---|---|---|
| GeneOntologyMolecularFunction | aspartic-type endopeptidase activity | ERVK-6 ERVK-8 ERVK-18 ERVK-19 ERVK-7 ERVK-21 ERVK-25 ERVK-9 ERVK-24 | 2.13e-16 | 37 | 50 | 9 | GO:0004190 |
| GeneOntologyMolecularFunction | aspartic-type peptidase activity | ERVK-6 ERVK-8 ERVK-18 ERVK-19 ERVK-7 ERVK-21 ERVK-25 ERVK-9 ERVK-24 | 2.79e-16 | 38 | 50 | 9 | GO:0070001 |
| GeneOntologyMolecularFunction | endopeptidase activity | ERVK-6 ADAMTS19 ERVK-8 ERVK-18 ERVK-19 ERVK-7 ERVK-21 ERVK-25 ERVK-9 ERVK-24 | 9.19e-08 | 430 | 50 | 10 | GO:0004175 |
| GeneOntologyMolecularFunction | peptidase activity | ERVK-6 ADAMTS19 ERVK-8 ERVK-18 ERVK-19 ERVK-7 ERVK-21 ERVK-25 ERVK-9 ERVK-24 DNPEP | 4.99e-07 | 654 | 50 | 11 | GO:0008233 |
| GeneOntologyMolecularFunction | RNA-DNA hybrid ribonuclease activity | 2.40e-06 | 11 | 50 | 3 | GO:0004523 | |
| GeneOntologyMolecularFunction | RNA-directed DNA polymerase activity | 5.27e-06 | 14 | 50 | 3 | GO:0003964 | |
| GeneOntologyMolecularFunction | RNA stem-loop binding | 1.90e-05 | 21 | 50 | 3 | GO:0035613 | |
| GeneOntologyMolecularFunction | structural molecule activity | ERVK-6 ERVK-8 ERVK-18 ERVK-19 ERVK-7 ERVK-21 SEC31A ERVK-25 ERVK-9 ERVK-24 | 6.02e-05 | 891 | 50 | 10 | GO:0005198 |
| GeneOntologyMolecularFunction | RNA endonuclease activity, producing 5'-phosphomonoesters | 1.08e-04 | 37 | 50 | 3 | GO:0016891 | |
| GeneOntologyMolecularFunction | DNA polymerase activity | 1.17e-04 | 38 | 50 | 3 | GO:0034061 | |
| GeneOntologyMolecularFunction | endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters | 2.08e-04 | 46 | 50 | 3 | GO:0016893 | |
| GeneOntologyMolecularFunction | zinc ion binding | ERVK-6 LTN1 ERVK-8 ERVK-19 ERVK-7 ERVK-21 ERVK-9 ERVK-24 DNPEP | 3.25e-04 | 891 | 50 | 9 | GO:0008270 |
| GeneOntologyMolecularFunction | nucleotidyltransferase activity | 5.66e-04 | 152 | 50 | 4 | GO:0016779 | |
| GeneOntologyMolecularFunction | sodium:chloride symporter activity | 8.16e-04 | 17 | 50 | 2 | GO:0015378 | |
| GeneOntologyMolecularFunction | RNA endonuclease activity | 1.02e-03 | 79 | 50 | 3 | GO:0004521 | |
| GeneOntologyMolecularFunction | monoatomic anion:sodium symporter activity | 1.02e-03 | 19 | 50 | 2 | GO:0015373 | |
| GeneOntologyMolecularFunction | transporter activity | SLC6A8 SLC12A3 PKD1 CYB561D1 GRIK4 CACHD1 SLC52A2 SLC7A7 SLC22A24 ATP10A | 1.16e-03 | 1289 | 50 | 10 | GO:0005215 |
| GeneOntologyMolecularFunction | chloride:monoatomic cation symporter activity | 1.50e-03 | 23 | 50 | 2 | GO:0015377 | |
| GeneOntologyMolecularFunction | monoatomic anion:monoatomic cation symporter activity | 1.92e-03 | 26 | 50 | 2 | GO:0015296 | |
| GeneOntologyMolecularFunction | transferase activity, transferring phosphorus-containing groups | 2.14e-03 | 938 | 50 | 8 | GO:0016772 | |
| GeneOntologyMolecularFunction | amino acid transmembrane transporter activity | 2.31e-03 | 105 | 50 | 3 | GO:0015171 | |
| GeneOntologyMolecularFunction | transmembrane transporter activity | SLC6A8 SLC12A3 PKD1 CYB561D1 GRIK4 CACHD1 SLC52A2 SLC7A7 SLC22A24 | 2.38e-03 | 1180 | 50 | 9 | GO:0022857 |
| GeneOntologyMolecularFunction | transition metal ion binding | ERVK-6 LTN1 ERVK-8 ERVK-19 ERVK-7 ERVK-21 ERVK-9 ERVK-24 DNPEP | 2.50e-03 | 1189 | 50 | 9 | GO:0046914 |
| GeneOntologyMolecularFunction | glucuronosyltransferase activity | 3.47e-03 | 35 | 50 | 2 | GO:0015020 | |
| GeneOntologyMolecularFunction | odorant binding | 3.96e-03 | 127 | 50 | 3 | GO:0005549 | |
| GeneOntologyMolecularFunction | RNA nuclease activity | 4.79e-03 | 136 | 50 | 3 | GO:0004540 | |
| GeneOntologyMolecularFunction | endonuclease activity | 4.79e-03 | 136 | 50 | 3 | GO:0004519 | |
| GeneOntologyMolecularFunction | metal ion transmembrane transporter activity | 6.00e-03 | 465 | 50 | 5 | GO:0046873 | |
| GeneOntologyMolecularFunction | organic anion transmembrane transporter activity | 6.16e-03 | 293 | 50 | 4 | GO:0008514 | |
| GeneOntologyBiologicalProcess | viral process | ERVK-6 ERVK-8 OAS3 ERVK-19 ERVK-7 ERVK-21 ERVK-9 SLC52A2 ERVK-24 | 1.80e-06 | 464 | 51 | 9 | GO:0016032 |
| GeneOntologyBiologicalProcess | cell-cell fusion | 2.14e-06 | 85 | 51 | 5 | GO:0140253 | |
| GeneOntologyBiologicalProcess | syncytium formation by plasma membrane fusion | 2.14e-06 | 85 | 51 | 5 | GO:0000768 | |
| GeneOntologyBiologicalProcess | syncytium formation | 2.68e-06 | 89 | 51 | 5 | GO:0006949 | |
| GeneOntologyBiologicalProcess | DNA integration | 4.00e-06 | 13 | 51 | 3 | GO:0015074 | |
| GeneOntologyBiologicalProcess | RNA-templated DNA biosynthetic process | 5.27e-05 | 83 | 51 | 4 | GO:0006278 | |
| GeneOntologyBiologicalProcess | peptidyl-serine autophosphorylation | 2.13e-04 | 9 | 51 | 2 | GO:0036289 | |
| GeneOntologyBiologicalProcess | DNA synthesis involved in DNA repair | 2.28e-04 | 48 | 51 | 3 | GO:0000731 | |
| Domain | ARM-type_fold | 9.38e-04 | 339 | 42 | 5 | IPR016024 | |
| Domain | AA-permease/SLC12A_dom | 1.11e-03 | 22 | 42 | 2 | IPR004841 | |
| Domain | AA_permease | 1.11e-03 | 22 | 42 | 2 | PF00324 | |
| Domain | Kelch-typ_b-propeller | 6.80e-03 | 55 | 42 | 2 | IPR015915 | |
| Domain | Kelch | 7.54e-03 | 58 | 42 | 2 | SM00612 | |
| Domain | BACK | 8.05e-03 | 60 | 42 | 2 | SM00875 | |
| Domain | BACK | 8.31e-03 | 61 | 42 | 2 | PF07707 | |
| Domain | BACK | 8.31e-03 | 61 | 42 | 2 | IPR011705 | |
| Domain | Kelch_1 | 1.08e-02 | 70 | 42 | 2 | PF01344 | |
| Domain | Kelch_1 | 1.08e-02 | 70 | 42 | 2 | IPR006652 | |
| Pubmed | Quantitation of HERV-K env gene expression and splicing in human breast cancer. | 6.77e-15 | 5 | 53 | 5 | 12629516 | |
| Pubmed | A revised nomenclature for transcribed human endogenous retroviral loci. | ERVK-6 ERVK-8 ERVK-18 ERVK-19 ERVK-7 ERVK-21 ERVK-25 ERVK-9 ERVK-24 | 2.09e-14 | 94 | 53 | 9 | 21542922 |
| Pubmed | 5.32e-12 | 12 | 53 | 5 | 14557543 | ||
| Pubmed | 5.71e-11 | 18 | 53 | 5 | 18664271 | ||
| Pubmed | 3.34e-09 | 3 | 53 | 3 | 10516026 | ||
| Pubmed | Many human endogenous retrovirus K (HERV-K) proviruses are unique to humans. | 1.34e-08 | 4 | 53 | 3 | 10469592 | |
| Pubmed | 6.66e-08 | 6 | 53 | 3 | 15063128 | ||
| Pubmed | 3.98e-07 | 10 | 53 | 3 | 12970426 | ||
| Pubmed | 2.28e-06 | 2 | 53 | 2 | 9060628 | ||
| Pubmed | Evolutionary relationships within a subgroup of HERV-K-related human endogenous retroviruses. | 2.28e-06 | 2 | 53 | 2 | 9460924 | |
| Pubmed | 2.28e-06 | 2 | 53 | 2 | 36293397 | ||
| Pubmed | The UGT2A1/UGT2A2 locus is associated with COVID-19-related loss of smell or taste. | 2.28e-06 | 2 | 53 | 2 | 35039640 | |
| Pubmed | 2.28e-06 | 2 | 53 | 2 | 11376859 | ||
| Pubmed | 2.28e-06 | 2 | 53 | 2 | 33802342 | ||
| Pubmed | Cloning and characterization of a novel human olfactory UDP-glucuronosyltransferase. | 2.28e-06 | 2 | 53 | 2 | 10359671 | |
| Pubmed | Interferon-alpha-induced endogenous superantigen. a model linking environment and autoimmunity. | 2.28e-06 | 2 | 53 | 2 | 11672541 | |
| Pubmed | ATM mediates spermidine-induced mitophagy via PINK1 and Parkin regulation in human fibroblasts. | 6.83e-06 | 3 | 53 | 2 | 27089984 | |
| Pubmed | 6.83e-06 | 3 | 53 | 2 | 9971820 | ||
| Pubmed | 6.83e-06 | 3 | 53 | 2 | 23756265 | ||
| Pubmed | 6.83e-06 | 3 | 53 | 2 | 19858781 | ||
| Pubmed | PINK1/Parkin Influences Cell Cycle by Sequestering TBK1 at Damaged Mitochondria, Inhibiting Mitosis. | 1.36e-05 | 4 | 53 | 2 | 31577952 | |
| Pubmed | 1.36e-05 | 4 | 53 | 2 | 7983737 | ||
| Pubmed | CTDP1 regulates breast cancer survival and DNA repair through BRCT-specific interactions with FANCI. | 1.97e-05 | 104 | 53 | 4 | 31240132 | |
| Pubmed | Transcriptionally active HERV-K genes: identification, isolation, and chromosomal mapping. | 2.27e-05 | 5 | 53 | 2 | 11401426 | |
| Pubmed | Nomenclature update for the mammalian UDP glycosyltransferase (UGT) gene superfamily. | 2.27e-05 | 5 | 53 | 2 | 16141793 | |
| Pubmed | Hepatic mTORC2 activates glycolysis and lipogenesis through Akt, glucokinase, and SREBP1c. | 2.27e-05 | 5 | 53 | 2 | 22521878 | |
| Pubmed | 3.40e-05 | 6 | 53 | 2 | 21177249 | ||
| Pubmed | Tti1 and Tel2 are critical factors in mammalian target of rapamycin complex assembly. | 1.24e-04 | 11 | 53 | 2 | 20427287 | |
| Pubmed | Activator-Mediator binding regulates Mediator-cofactor interactions. | 1.24e-04 | 11 | 53 | 2 | 20534441 | |
| Pubmed | Tel2 structure and function in the Hsp90-dependent maturation of mTOR and ATR complexes. | 3.83e-04 | 19 | 53 | 2 | 20801936 | |
| Pubmed | 5.65e-04 | 23 | 53 | 2 | 29742433 | ||
| Pubmed | 6.68e-04 | 25 | 53 | 2 | 19876004 | ||
| Pubmed | 1.24e-03 | 34 | 53 | 2 | 35341793 | ||
| Pubmed | 1.39e-03 | 36 | 53 | 2 | 33737325 | ||
| Cytoband | 3q11.2 | 4.02e-04 | 26 | 52 | 2 | 3q11.2 | |
| Cytoband | Ensembl 112 genes in cytogenetic band chr3q11 | 1.73e-03 | 54 | 52 | 2 | chr3q11 | |
| GeneFamily | Solute carriers | 1.17e-04 | 395 | 36 | 6 | 752 | |
| GeneFamily | UDP glucuronosyltransferases | 1.84e-03 | 32 | 36 | 2 | 363 | |
| GeneFamily | Kelch like|BTB domain containing | 3.16e-03 | 42 | 36 | 2 | 617 | |
| Coexpression | GSE21360_NAIVE_VS_SECONDARY_MEMORY_CD8_TCELL_DN | 4.97e-07 | 177 | 44 | 6 | M7632 | |
| Coexpression | GSE17721_POLYIC_VS_CPG_12H_BMDC_DN | 2.10e-05 | 200 | 44 | 5 | M3949 | |
| Computational | Genes in the cancer module 171. | 1.91e-04 | 138 | 23 | 4 | MODULE_171 | |
| Drug | Cinnarizine [298-57-7]; Down 200; 10.8uM; HL60; HG-U133A | 2.32e-06 | 196 | 45 | 6 | 1558_DN | |
| Disease | Abnormality of the sense of smell, COVID-19 symptoms measurement, ageusia | 2.07e-06 | 2 | 43 | 2 | EFO_0600019, EFO_1001758, HP_0004408 | |
| Disease | lung small cell carcinoma (is_implicated_in) | 9.21e-06 | 28 | 43 | 3 | DOID:5409 (is_implicated_in) | |
| Disease | stomach cancer (is_marker_for) | 1.17e-03 | 142 | 43 | 3 | DOID:10534 (is_marker_for) | |
| Disease | malignant epithelial tumor of ovary | 1.20e-03 | 35 | 43 | 2 | MONDO_0018364 | |
| Disease | renal cell carcinoma | 1.72e-03 | 42 | 43 | 2 | EFO_0000681 | |
| Disease | reading | 1.80e-03 | 43 | 43 | 2 | EFO_0005229 | |
| Disease | Medulloblastoma | 2.43e-03 | 50 | 43 | 2 | C0025149 | |
| Disease | uterine fibroid | 3.06e-03 | 199 | 43 | 3 | EFO_0000731 | |
| Disease | Malignant neoplasm of breast | 4.42e-03 | 1074 | 43 | 6 | C0006142 | |
| Disease | esophagus squamous cell carcinoma (is_marker_for) | 5.24e-03 | 74 | 43 | 2 | DOID:3748 (is_marker_for) | |
| Disease | urinary metabolite measurement | 5.46e-03 | 245 | 43 | 3 | EFO_0005116 | |
| Disease | Parkinson's disease (is_implicated_in) | 5.52e-03 | 76 | 43 | 2 | DOID:14330 (is_implicated_in) |
| Peptide | Gene | Start | Entry |
|---|---|---|---|
| LATAVQALCGLCLLC | 136 | Q8N8Q1 | |
| CLFCLLLVCRCTQQL | 536 | O42043 | |
| VCLFCLLLVCRCTQQ | 646 | O71037 | |
| VCLFCLLLVCRCTQQ | 646 | Q902F8 | |
| CLFCLLLVCRCTQQL | 646 | Q9UKH3 | |
| LHSCFCALQALIDSC | 276 | Q9ULA0 | |
| ALAQLVAQRAACCLA | 21 | O95336 | |
| ALLCACTSCLQANYT | 31 | P36896 | |
| VCEQSCAALCFLALR | 386 | Q6NXE6 | |
| LAFCACSMVDRLCLN | 946 | Q5VU97 | |
| EACAALLDQCLCYVQ | 921 | O60312 | |
| IFLGNLALVDSCCAC | 61 | Q8NHB8 | |
| ICCCCLLYQLGFLSN | 6 | Q8TE59 | |
| QLFACVSCDLACDLS | 1271 | O94822 | |
| ALCLAYSRCSINICQ | 106 | Q9Y442 | |
| CGLFTAILCCNLIEN | 91 | Q9NPJ1 | |
| SLFVICALSLAACLC | 181 | Q96N19 | |
| NLECETLCQAALLLC | 561 | Q9BXM7 | |
| AQLCAAALAAVLSCL | 396 | P52790 | |
| TACLLQLSQVVEACC | 296 | Q96PQ7 | |
| LEKCSVFQCLLNLCS | 676 | Q6R327 | |
| VCLFCLLLVCRCTQQ | 1406 | P63135 | |
| IFLGNLALVDSCCAC | 61 | Q8NHB7 | |
| FSLCCDLLSQVCQTA | 1491 | Q13315 | |
| CSFLLAKICLENCAE | 121 | Q96M94 | |
| CLFCLLLVCRCTQQL | 536 | P61566 | |
| VCLFCLLLVCRCTQQ | 646 | P61570 | |
| VCLFCLLLVCRCTQQ | 646 | Q69384 | |
| CLFCLLLVCRCTQQL | 536 | P61567 | |
| CVLFLCTALIANCFW | 226 | Q8TDV2 | |
| CCLFDLKALCSILNQ | 721 | Q5SZL2 | |
| CLFCLLLVCRCTQQL | 646 | P61565 | |
| TACLICAKAECLLNL | 161 | Q16099 | |
| ICFLTCISLQRCFFL | 121 | O00398 | |
| ATCCVLLICLFLGAN | 3281 | P98161 | |
| LLAKEAAACTSALCC | 1056 | Q9Y6K5 | |
| CLAALLFQLLVAVCF | 16 | P21217 | |
| FLCALCVSALCRQLE | 441 | Q8IYR2 | |
| CKLCFLQLAISNTCA | 176 | Q8N4F4 | |
| VLGASACCLACVFTN | 11 | Q6PIV7 | |
| ALAFVLALACCASNV | 116 | Q9HAB3 | |
| CELRVLCCFAFSLSQ | 701 | Q96HU1 | |
| FQREISVALCCALCF | 441 | P48029 | |
| CLLLVTLALCCYQAN | 6 | O95969 | |
| VALSNSICLACFCAN | 951 | Q5T5C0 | |
| SRLALCTLVFLCLSC | 486 | P36956 | |
| FNTLFCRLCVLLLVC | 286 | Q15035 | |
| LAAACICLLTFINCA | 161 | Q9UM01 | |
| ACLVSAAKVFQCLCE | 471 | P55017 | |
| DSLLQTQACLCYICA | 681 | O94979 | |
| TAIFLVIQCCLFSCQ | 501 | P0DTE4 | |
| AIFLVIQCCLFSCQK | 511 | P0DTE5 | |
| CQSSILCYQLACELL | 861 | Q9P2D8 | |
| QTLRLESCNLTVFCC | 761 | Q86W24 | |
| LCCQDLSSALICNKR | 1001 | Q86W24 |