Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
MousePhenoabnormal subclavian artery morphology

CMIP AMN PRMT7

5.64e-0556193MP:0003395
MousePhenoabnormal coronary sinus connection

CMIP PRMT7

1.35e-0413192MP:0013975
MousePhenoembryo tumor

CMIP PRMT7

2.35e-0417192MP:0014018
MousePhenoabnormal coronary sinus morphology

CMIP PRMT7

2.64e-0418192MP:0010436
MousePhenoretroesophageal right subclavian artery

CMIP PRMT7

3.98e-0422192MP:0004160
MousePhenoabnormal vitelline vein topology

CMIP PRMT7

3.98e-0422192MP:0013986
MousePhenoabnormal aortic arch morphology

CMIP AMN PRMT7

5.28e-04119193MP:0004113
MousePhenoabsent segment of posterior cerebral artery

CMIP PRMT7

6.48e-0428192MP:0013840
MousePhenoabnormal posterior cerebral artery morphology

CMIP PRMT7

6.48e-0428192MP:0013839
MousePhenoabnormal thoracic aorta morphology

CMIP AMN PRMT7

7.46e-04134193MP:0010468
MousePhenoabnormal cerebral artery morphology

CMIP PRMT7

8.47e-0432192MP:0013821
MousePhenoaberrant origin of the right subclavian artery

CMIP PRMT7

9.01e-0433192MP:0010465
MousePhenoabnormal vitelline vein morphology

CMIP PRMT7

9.57e-0434192MP:0010666
MousePhenodual inferior vena cava

CMIP PRMT7

9.57e-0434192MP:0011683
MousePhenoabnormal aortic arch and aortic arch branch attachment

CMIP PRMT7

1.13e-0337192MP:0010464
Domain-

GTF2IRD2 GTF2IRD2B

1.30e-0542823.90.1460.10
DomainGTF2I

GTF2IRD2 GTF2IRD2B

1.30e-054282IPR004212
DomainGTF2I

GTF2IRD2 GTF2IRD2B

1.30e-054282PS51139
DomainGTF2I

GTF2IRD2 GTF2IRD2B

1.30e-054282PF02946
DomainSushi_SCR_CCP_dom

C1RL F13B

3.29e-0357282IPR000436
DomainRNaseH-like_dom

GTF2IRD2 GTF2IRD2B

4.78e-0369282IPR012337
Pubmed

Comparison of TFII-I gene family members deleted in Williams-Beuren syndrome.

GTF2IRD2 GTF2IRD2B

6.25e-07228215388857
Pubmed

Isolation and characterisation of GTF2IRD2, a novel fusion gene and member of the TFII-I family of transcription factors, deleted in Williams-Beuren syndrome.

GTF2IRD2 GTF2IRD2B

1.87e-06328215100712
Pubmed

The TIP60 Complex Is a Conserved Coactivator of HIF1A.

MON2 POLRMT MSH2 NSF

2.59e-0612028427320910
Pubmed

Haploinsufficiency of Gtf2i, a gene deleted in Williams Syndrome, leads to increases in social interactions.

GTF2IRD2 GTF2IRD2B

3.75e-06428221328569
Pubmed

TFII-I gene family during tooth development: candidate genes for tooth anomalies in Williams syndrome.

GTF2IRD2 GTF2IRD2B

3.75e-06428217823943
Pubmed

Evolution of general transcription factors.

GTF2IRD2 GTF2IRD2B

3.75e-06428223229069
Pubmed

GTF2IRD2 from the Williams-Beuren critical region encodes a mobile-element-derived fusion protein that antagonizes the action of its related family members.

GTF2IRD2 GTF2IRD2B

3.75e-06428222899722
Pubmed

Transcriptional fates of human-specific segmental duplications in brain.

GTF2IRD2 GTF2IRD2B

1.06e-041928230228200
Pubmed

A protein-interaction network of interferon-stimulated genes extends the innate immune system landscape.

MON2 POLRMT ATP5MF MSH2 INF2 NSF COMMD7

1.13e-04144028730833792
Pubmed

Novel loci for adiponectin levels and their influence on type 2 diabetes and metabolic traits: a multi-ethnic meta-analysis of 45,891 individuals.

CMIP PBRM1

1.30e-042128222479202
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

MON2 POLRMT SPHK2 INF2 TESK1 THAP11

2.10e-04110528635748872
Pubmed

BCAR1 promotes proliferation and cell growth in lung adenocarcinoma via upregulation of POLR2A.

MON2 GRK4 SLIT1 APOBEC3H

3.38e-0441928433001583
Pubmed

The core SWI/SNF catalytic subunit Brg1 regulates nephron progenitor cell proliferation and differentiation.

ATP5MF PBRM1

3.66e-043528232504627
Pubmed

Delineating WWOX Protein Interactome by Tandem Affinity Purification-Mass Spectrometry: Identification of Top Interactors and Key Metabolic Pathways Involved.

MSH2 TRIP6 NSF

6.99e-0421728330619736
Cytoband7q11.23

GTF2IRD2 GTF2IRD2B

1.61e-03972827q11.23
Cytoband16q22.1

PRMT7 THAP11

2.06e-0311028216q22.1
CytobandEnsembl 112 genes in cytogenetic band chr16q22

PRMT7 THAP11

5.58e-03183282chr16q22
CytobandEnsembl 112 genes in cytogenetic band chr7q22

ATP5MF TRIP6

7.89e-03219282chr7q22
GeneFamilyHyalectan proteoglycans|V-set domain containing|Sushi domain containing|C-type lectin domain containing

C1RL F13B

9.99e-04571521179
CoexpressionGSE22140_HEALTHY_VS_ARTHRITIC_GERMFREE_MOUSE_CD4_TCELL_UP

POLRMT SLC6A12 SPHK2 TESK1

5.83e-05200284M7648
CoexpressionGSE19401_NAIVE_VS_IMMUNIZED_MOUSE_PLN_FOLLICULAR_DC_DN

POLRMT SLC6A12 SPHK2 MSH2

5.83e-05200284M7658
CoexpressionGSE17721_PAM3CSK4_VS_GADIQUIMOD_12H_BMDC_UP

ATP5MF PRMT7 COMMD7 THAP11

5.83e-05200284M3974
ToppCellfacs-Liver-Hepatocytes|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC6A12 C1RL F13B SLC27A5

2.67e-06156284e2cda3ad4e5f44a80133864c5a38b766afb952ce
ToppCellTCGA-Endometrium-Primary_Tumor-Endometrial_Adenocarcinoma-Serous_adenocarcinoma-3|TCGA-Endometrium / Sample_Type by Project: Shred V9

SLC6A12 TMEM171 AMN INF2

2.74e-06157284ef70abc999be3a2c1eed7d21aef4b484f69d8567
ToppCellfacs-Liver-Hepatocytes-24m-Epithelial|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC6A12 C1RL F13B SLC27A5

4.92e-06182284770ce9f3f4538d0181a0181543841bc964c68274
ToppCellfacs-Liver-Hepatocytes-24m-Epithelial-nan|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC6A12 C1RL F13B SLC27A5

4.92e-0618228477ab860e2add49dad0c1ffbfc64278ad499dfbd5
ToppCellfacs-Liver-Hepatocytes-24m-Epithelial-hepatocyte|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC6A12 C1RL F13B SLC27A5

4.92e-061822844921c7d5687cc79f896b39753bb621d7e3d2972f
DiseaseBMI-adjusted adiponectin measurement

CMIP PBRM1

8.40e-0515272EFO_0007737
Diseaselymphocyte count

GTF2IRD2 TMEM171 SPHK2 GTF2IRD2B CMIP PBRM1 AMN

2.70e-041464277EFO_0004587
Diseaselymphocyte percentage of leukocytes

GTF2IRD2 ATP5MF SPHK2 GTF2IRD2B CMIP

3.06e-04665275EFO_0007993
DiseaseBMI-adjusted waist-hip ratio, physical activity measurement

CMIP PBRM1

1.82e-0369272EFO_0007788, EFO_0008002
Diseasecardiomyopathy (implicated_via_orthology)

SPHK2 AMN

1.93e-0371272DOID:0050700 (implicated_via_orthology)
Diseasesmoking behavior, BMI-adjusted waist-hip ratio

CMIP PBRM1

2.81e-0386272EFO_0004318, EFO_0007788
Diseasefeeling nervous measurement

PBRM1 NSF

2.88e-0387272EFO_0009597
Diseasetriglyceride measurement, alcohol drinking

CMIP NEIL2

3.70e-0399272EFO_0004329, EFO_0004530
Diseasetriglyceride measurement, alcohol consumption measurement

CMIP NEIL2

3.85e-03101272EFO_0004530, EFO_0007878
Diseaselanguage measurement

CMIP SLIT1

6.67e-03134272EFO_0007797
Diseaseobsolete_red blood cell distribution width

GTF2IRD2 TMEM171 SPHK2 GTF2IRD2B PBRM1

6.86e-031347275EFO_0005192
Diseaselung non-small cell carcinoma (is_implicated_in)

MSH2 PBRM1

7.16e-03139272DOID:3908 (is_implicated_in)
Diseaseadiponectin measurement

CMIP PBRM1

7.87e-03146272EFO_0004502

Protein segments in the cluster

PeptideGeneStartEntry
RGTLPVDQEKCGMGP

ANKRD34C

346

P0C6C1
LCGSQVPVEVMGFPE

APOBEC3H

126

Q6NTF7
DVSAPEGTKMGAVPC

CMIP

26

Q8IY22
TPCAGGAVEFPADKM

AMN

41

Q9BXJ7
KEDVPVEMSNGEPGC

PBRM1

1131

Q86U86
CPAGHQVMKEAFGPE

NEIL2

291

Q969S2
CKHPPVVMNGAVADG

F13B

396

P05160
PPEIVEQMGCKHVKG

NSF

241

P46459
EVVQPFLMGCGTKEP

MON2

66

Q7Z3U7
CSPPVAGGMEEVIVA

INF2

526

Q27J81
GDNGKMVCSIPEDIP

PCDHB12

376

Q9Y5F1
MASVGECPAPVPVKD

ATP5MF

1

P56134
VTVGPEGDMPCRANI

PRMT7

126

Q9NVM4
DGEEVLQCMPVCGRP

C1RL

221

Q9NZP8
CTEDPVPEAVGGDMQ

COMMD7

6

Q86VX2
GGCLTMVPSEKEVEP

GRK4

561

P32298
GCVVIDGMPPGVVFK

GTF2IRD2

366

Q86UP8
GCVVIDGMPPGVVFK

GTF2IRD2B

366

Q6EKJ0
KVQMGAKDATPVPCG

POLRMT

106

O00411
PKECVLPGGETAGDM

MSH2

196

P43246
MDGKVAVQECGPPAV

SLC6A12

1

P48065
VCGGAIMPEPGQEET

TRIP6

401

Q15654
AVKMPVGILPCGSGN

SPHK2

266

Q9NRA0
CVPGCEGKVGMAAVQ

SLC27A5

586

Q9Y2P5
GPPAVGPSAEEKMEC

TESK1

456

Q15569
PMVLKVAGPACAVVG

TMEM171

56

Q8WVE6
KEPGIARCAGPQDME

SLIT1

886

O75093
AECPMGPQLVVVGEE

THAP11

221

Q96EK4