Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionextracellular matrix constituent, lubricant activity

MUC17 MUC3A MUC4

2.16e-0641643GO:0030197
GeneOntologyMolecularFunctiontau-protein kinase activity

MARK3 TAOK2 TTBK1 BRSK1

2.86e-05221644GO:0050321
GeneOntologyMolecularFunctionbeta-catenin destruction complex binding

AMER1 LRRK2

6.70e-0521642GO:1904713
GeneOntologyBiologicalProcessregulation of neuron projection development

EPHB3 MBOAT1 MYCBP2 MAPT PPFIA2 FAT3 LRRK2 EZH2 IL1RAPL1 KANK1 CCDC88A NF1 PTPRZ1 COBL AFDN BRSK1 NDRG4 PLXNA2 INPP5J

3.97e-0761216319GO:0010975
GeneOntologyBiologicalProcessanimal organ morphogenesis

TREX1 TBX3 FAT4 SDK2 TCF7L2 FAT3 CYP27B1 LRRK2 DYNC2I1 MMP20 FOXI3 SHROOM2 ITGB4 SLC6A4 HOXA9 NF1 ALMS1 LRIG1 GLI1 EPHA2 HEY2 AFDN SLITRK6 CSMD1 NDRG4 NOTCH1 SOS1

2.33e-06126916327GO:0009887
GeneOntologyBiologicalProcessembryonic organ development

TBX3 TCF7L2 TMEM94 DYNC2I1 BIRC6 HOXA9 FOXD3 LRIG1 GLI1 EPHA2 HEY2 COBL SLITRK6 HECTD1 NDRG4 NOTCH1 RAD23B

2.34e-0656116317GO:0048568
GeneOntologyBiologicalProcessneuron projection development

EPHB3 FAT4 MBOAT1 MYCBP2 MAPT PPFIA2 FAT3 LRRK2 EZH2 TAOK2 IL1RAPL1 KANK1 CCDC88A NF1 ALMS1 PTPRZ1 COBL AFDN PRKG1 SLITRK6 BRSK1 NDRG4 PLXNA2 NOTCH1 INPP5J OTOG SOS1

2.94e-06128516327GO:0031175
GeneOntologyBiologicalProcessneuron development

EPHB3 FAT4 MBOAT1 MYCBP2 MAPT PPFIA2 FAT3 LRRK2 SCYL1 EZH2 TAOK2 IL1RAPL1 KANK1 CCDC88A NF1 ALMS1 PTPRZ1 COBL AFDN PRKG1 SLITRK6 BRSK1 NDRG4 PLXNA2 NOTCH1 INPP5J TBCD OTOG SOS1

3.78e-06146316329GO:0048666
GeneOntologyBiologicalProcesscell junction organization

EPHB3 COL4A1 SDK2 INSYN1 MYCBP2 MAPT PPFIA2 LRRK2 PCDHB8 GRID1 SYNDIG1 GRM5 SHROOM2 ITGB4 TAOK2 IL1RAPL1 SLC9A1 NF1 EPHA2 AFDN SLITRK6 TBCD

8.89e-0697416322GO:0034330
GeneOntologyBiologicalProcessregulation of nervous system development

EPHB3 TCF7L2 MAPT SYNDIG1 EZH2 GRM5 IL1RAPL1 LPIN1 TTBK1 NF1 PTPRZ1 HEY2 AFDN SLITRK6 IL33 PLXNA2 NOTCH1

9.75e-0662516317GO:0051960
GeneOntologyBiologicalProcessregulation of plasma membrane bounded cell projection organization

EPHB3 MBOAT1 MYCBP2 MAPT PPFIA2 FAT3 LRRK2 EZH2 IL1RAPL1 KANK1 CCDC88A NF1 PTPRZ1 EPHA2 COBL AFDN BRSK1 NDRG4 PLXNA2 INPP5J

1.23e-0584616320GO:0120035
GeneOntologyBiologicalProcessregulation of cell projection organization

EPHB3 MBOAT1 MYCBP2 MAPT PPFIA2 FAT3 LRRK2 EZH2 IL1RAPL1 KANK1 CCDC88A NF1 PTPRZ1 EPHA2 COBL AFDN BRSK1 NDRG4 PLXNA2 INPP5J

1.63e-0586316320GO:0031344
GeneOntologyBiologicalProcesscell morphogenesis

EPHB3 MYCBP2 MAPT PPFIA2 FAT3 LRRK2 VSIG1 SHROOM2 TAOK2 IL1RAPL1 KANK1 PTPRZ1 EPHA2 COBL AFDN PRKG1 SLITRK6 BRSK1 MUC3A FGD6 PLXNA2 NOTCH1 TBCD SOS1

2.32e-05119416324GO:0000902
GeneOntologyBiologicalProcesscell-substrate adhesion

EPHB3 PPFIA2 ITGAE ITGB4 TAOK2 SLC9A1 KANK1 NF1 PTPRZ1 SIGLEC1 MUC4 NOTCH1 TBCD

2.39e-0541016313GO:0031589
GeneOntologyBiologicalProcesscentral nervous system development

EPHB3 COL4A1 TBX3 DMXL2 FAT4 TCF7L2 MYCBP2 MAPT LRRK2 SCYL1 EZH2 SHROOM2 SLC6A4 NCOR1 TTBK1 NF1 PTPRZ1 GLI1 AFDN PRKG1 IL33 PLXNA2 NOTCH1 SOS1

2.42e-05119716324GO:0007417
GeneOntologyBiologicalProcessnegative regulation of small molecule metabolic process

TCF7L2 ACADVL UBR4 CYP27B1 SIK1 NCOR1 PRKG1 DKKL1

2.48e-051491638GO:0062014
GeneOntologyBiologicalProcessnegative regulation of cell-substrate adhesion

KANK1 NF1 PTPRZ1 MUC4 NOTCH1 TBCD

2.64e-05741636GO:0010812
GeneOntologyBiologicalProcesscell morphogenesis involved in neuron differentiation

EPHB3 MYCBP2 MAPT PPFIA2 FAT3 LRRK2 TAOK2 IL1RAPL1 PTPRZ1 COBL AFDN PRKG1 SLITRK6 BRSK1 PLXNA2 NOTCH1 TBCD SOS1

2.73e-0574816318GO:0048667
GeneOntologyBiologicalProcesssynapse organization

EPHB3 COL4A1 SDK2 INSYN1 MYCBP2 MAPT PPFIA2 LRRK2 PCDHB8 GRID1 SYNDIG1 GRM5 TAOK2 IL1RAPL1 NF1 AFDN SLITRK6

3.14e-0568516317GO:0050808
GeneOntologyBiologicalProcesshead development

EPHB3 COL4A1 TRABD2A TBX3 DMXL2 FAT4 TCF7L2 LRRK2 EZH2 SHROOM2 SLC6A4 NCOR1 TTBK1 NF1 GLI1 AFDN PRKG1 PLXNA2 NOTCH1 SOS1

3.98e-0591916320GO:0060322
GeneOntologyBiologicalProcessbrain development

EPHB3 COL4A1 TBX3 DMXL2 FAT4 TCF7L2 LRRK2 EZH2 SHROOM2 SLC6A4 NCOR1 TTBK1 NF1 GLI1 AFDN PRKG1 PLXNA2 NOTCH1 SOS1

5.07e-0585916319GO:0007420
GeneOntologyBiologicalProcessdendrite development

EPHB3 PPFIA2 FAT3 LRRK2 EZH2 TAOK2 IL1RAPL1 PTPRZ1 COBL AFDN PRKG1

7.52e-0533516311GO:0016358
GeneOntologyBiologicalProcessepithelium development

COL4A1 TBX3 FAT4 TCF7L2 TMEM94 CYP27B1 VSIG1 EZH2 FOXI3 NCOR1 NF1 ALMS1 GLI1 EPHA2 HEY2 COBL AFDN DMBT1 SLITRK6 CSMD1 BRSK1 HECTD1 NDRG4 PLXNA2 NOTCH1 SOS1

8.77e-05146916326GO:0060429
GeneOntologyBiologicalProcessear development

TBX3 FAT4 SHROOM2 ALMS1 LRIG1 KCNK3 HEY2 SLITRK6 NOTCH1 OTOG

9.32e-0528516310GO:0043583
GeneOntologyBiologicalProcessregulation of oligodendrocyte differentiation

TCF7L2 NF1 PTPRZ1 IL33 NOTCH1

9.47e-05581635GO:0048713
GeneOntologyBiologicalProcesscell projection morphogenesis

EPHB3 MYCBP2 MAPT PPFIA2 LRRK2 TAOK2 IL1RAPL1 KANK1 PTPRZ1 COBL AFDN PRKG1 SLITRK6 BRSK1 MUC3A PLXNA2 NOTCH1 SOS1

9.76e-0582616318GO:0048858
GeneOntologyBiologicalProcessinner ear receptor cell differentiation

FAT4 ALMS1 HEY2 SLITRK6 NOTCH1 OTOG

1.15e-04961636GO:0060113
GeneOntologyBiologicalProcessregulation of lipid metabolic process

TREX1 TCF7L2 ACADVL MAPT UBR4 CYP27B1 SIK1 IRS1 NCOR1 PRKAA2 PRKG1 DKKL1

1.19e-0441516312GO:0019216
GeneOntologyBiologicalProcesspositive regulation of nervous system development

EPHB3 MAPT SYNDIG1 GRM5 IL1RAPL1 TTBK1 PTPRZ1 AFDN SLITRK6 IL33 PLXNA2 NOTCH1

1.27e-0441816312GO:0051962
GeneOntologyBiologicalProcessforebrain development

EPHB3 TBX3 DMXL2 FAT4 TCF7L2 LRRK2 EZH2 NCOR1 NF1 GLI1 AFDN PRKG1 NOTCH1

1.42e-0448916313GO:0030900
GeneOntologyBiologicalProcessembryo development

TBX3 TCF7L2 TMEM94 DYNC2I1 FOXI3 BIRC6 HOXA9 NCOR1 FOXD3 SLC9A1 NF1 LRIG1 GLI1 EPHA2 HEY2 COBL DMBT1 SLITRK6 HECTD1 HCFC1 NDRG4 PLXNA2 NOTCH1 SOS1 RAD23B

1.59e-04143716325GO:0009790
GeneOntologyBiologicalProcesscell junction assembly

EPHB3 SDK2 MYCBP2 MAPT PCDHB8 SYNDIG1 ITGB4 TAOK2 IL1RAPL1 SLC9A1 EPHA2 AFDN SLITRK6 TBCD

1.76e-0456916314GO:0034329
GeneOntologyBiologicalProcessmechanoreceptor differentiation

FAT4 ALMS1 HEY2 SLITRK6 NOTCH1 OTOG

1.78e-041041636GO:0042490
GeneOntologyBiologicalProcessregulation of glial cell differentiation

TCF7L2 TTBK1 NF1 PTPRZ1 IL33 NOTCH1

1.78e-041041636GO:0045685
GeneOntologyBiologicalProcessCD86 biosynthetic process

TREX1 IL33

1.85e-0431632GO:0035781
GeneOntologyBiologicalProcesspositive regulation of heparan sulfate proteoglycan biosynthetic process

TCF7L2 PXYLP1

1.85e-0431632GO:0010909
GeneOntologyBiologicalProcessinner ear development

TBX3 FAT4 ALMS1 LRIG1 KCNK3 HEY2 SLITRK6 NOTCH1 OTOG

1.89e-042531639GO:0048839
GeneOntologyBiologicalProcesssensory organ development

COL4A1 TBX3 FAT4 SDK2 FAT3 SHROOM2 NF1 ALMS1 LRIG1 EPHA2 KCNK3 HEY2 SLITRK6 NOTCH1 OTOG SOS1

2.27e-0473016316GO:0007423
GeneOntologyBiologicalProcessglial cell differentiation

TCF7L2 MAPT ITGB4 TTBK1 NF1 PTPRZ1 AFDN IL33 NOTCH1 SOS1

2.45e-0432116310GO:0010001
GeneOntologyBiologicalProcessregulation of synapse organization

EPHB3 MYCBP2 PPFIA2 LRRK2 GRID1 SYNDIG1 TAOK2 IL1RAPL1 NF1 AFDN SLITRK6

2.65e-0438716311GO:0050807
GeneOntologyBiologicalProcessplasma membrane bounded cell projection morphogenesis

EPHB3 MYCBP2 MAPT PPFIA2 LRRK2 TAOK2 IL1RAPL1 KANK1 PTPRZ1 COBL AFDN PRKG1 SLITRK6 BRSK1 PLXNA2 NOTCH1 SOS1

2.72e-0481916317GO:0120039
GeneOntologyBiologicalProcessgrowth

TCF7L2 MYCBP2 MAPT CYP27B1 DAXX MUC12 EZH2 TAOK2 SLC6A4 NCOR1 SLC9A1 ALMS1 GLI1 HEY2 COBL AFDN PRKG1 DMBT1 SLITRK6 NDRG4 NOTCH1 SOS1

2.96e-04123516322GO:0040007
GeneOntologyBiologicalProcessepidermis development

COL7A1 CYP27B1 EZH2 FOXI3 NCOR1 NF1 GLI1 EPHA2 HEY2 SLITRK6 NOTCH1 SOS1

3.12e-0446116312GO:0008544
GeneOntologyBiologicalProcessregulation of synapse structure or activity

EPHB3 MYCBP2 PPFIA2 LRRK2 GRID1 SYNDIG1 TAOK2 IL1RAPL1 NF1 AFDN SLITRK6

3.15e-0439516311GO:0050803
GeneOntologyBiologicalProcessdevelopmental growth

TCF7L2 MYCBP2 MAPT DAXX EZH2 SLC6A4 NCOR1 ALMS1 GLI1 HEY2 COBL AFDN PRKG1 DMBT1 SLITRK6 NDRG4 NOTCH1 SOS1

3.25e-0491116318GO:0048589
GeneOntologyBiologicalProcesscell-cell adhesion

EPHB3 FAT4 SDK2 PCDHGB1 FAT3 PCDHB12 PCDHB8 ITGAE UBASH3A ITGB4 LAX1 TAOK2 SLC6A4 IL1RAPL1 CD33 AFDN SIGLEC1 PRKG1 MUC4 NOTCH1

3.35e-04107716320GO:0098609
GeneOntologyBiologicalProcessnegative regulation of cell proliferation involved in heart morphogenesis

TBX3 NOTCH1

3.69e-0441632GO:2000137
GeneOntologyBiologicalProcessregulation of heparan sulfate proteoglycan biosynthetic process

TCF7L2 PXYLP1

3.69e-0441632GO:0010908
GeneOntologyBiologicalProcesssensory organ morphogenesis

TBX3 SDK2 FAT3 SHROOM2 NF1 ALMS1 LRIG1 EPHA2 SLITRK6 NOTCH1

4.13e-0434316310GO:0090596
GeneOntologyBiologicalProcessG1 to G0 transition

CYP27B1 EZH2 WDR6

4.28e-04191633GO:0070314
GeneOntologyBiologicalProcesscamera-type eye morphogenesis

SDK2 FAT3 SHROOM2 NF1 ALMS1 EPHA2 NOTCH1

4.29e-041711637GO:0048593
GeneOntologyBiologicalProcessregulation of striated muscle cell differentiation

TRIM72 SIK1 DAXX EZH2 EPC1 NOTCH1

4.41e-041231636GO:0051153
GeneOntologyBiologicalProcessdendritic spine morphogenesis

EPHB3 PPFIA2 LRRK2 IL1RAPL1 AFDN

4.58e-04811635GO:0060997
GeneOntologyBiologicalProcessregulation of cellular component biogenesis

EPHB3 TRABD2A MYCBP2 MAPT LRRK2 SYNDIG1 IL1RAPL1 SLC9A1 KANK1 TTBK1 CCDC88A ALMS1 EPHA2 PRKAA2 COBL AFDN SLITRK6 HCFC1 NOTCH1 INPP5J TBCD

4.59e-04118916321GO:0044087
GeneOntologyBiologicalProcesstrans-synaptic signaling

DMXL2 INSYN1 TSPOAP1 MAPT PPFIA2 LRRK2 PCDHB8 GRID1 NR4A1 EZH2 GRM5 SLC6A4 IL1RAPL1 NF1 KCNK3 AFDN BRSK1 NOTCH1

4.65e-0493916318GO:0099537
GeneOntologyBiologicalProcessembryonic organ morphogenesis

TBX3 TCF7L2 DYNC2I1 HOXA9 LRIG1 GLI1 EPHA2 SLITRK6 NDRG4 NOTCH1

4.95e-0435116310GO:0048562
GeneOntologyBiologicalProcesspositive regulation of neuroinflammatory response

LRRK2 TTBK1 IL33

5.00e-04201633GO:0150078
GeneOntologyBiologicalProcessgland development

EPHB3 TBX3 TCF7L2 IRS1 EZH2 FOXI3 HOXA9 NF1 GLI1 EPHA2 COBL CSMD1 NOTCH1

5.06e-0455816313GO:0048732
GeneOntologyBiologicalProcessnegative regulation of muscle cell differentiation

TRIM72 DAXX EZH2 HEY2 NOTCH1

5.12e-04831635GO:0051148
GeneOntologyBiologicalProcessregulation of developmental growth

TCF7L2 MYCBP2 MAPT DAXX SLC6A4 NCOR1 ALMS1 GLI1 HEY2 AFDN NOTCH1

5.38e-0442116311GO:0048638
GeneOntologyBiologicalProcessnegative regulation of myotube differentiation

TRIM72 DAXX NOTCH1

5.80e-04211633GO:0010832
GeneOntologyBiologicalProcessbrain morphogenesis

SLC6A4 NF1 AFDN SOS1

6.04e-04491634GO:0048854
GeneOntologyBiologicalProcesscardiac vascular smooth muscle cell development

HEY2 NOTCH1

6.11e-0451632GO:0060948
GeneOntologyBiologicalProcesspositive regulation of proteoglycan biosynthetic process

TCF7L2 PXYLP1

6.11e-0451632GO:1902730
GeneOntologyBiologicalProcessneuron projection morphogenesis

EPHB3 MYCBP2 MAPT PPFIA2 LRRK2 TAOK2 IL1RAPL1 PTPRZ1 COBL AFDN PRKG1 SLITRK6 BRSK1 PLXNA2 NOTCH1 SOS1

6.36e-0480216316GO:0048812
GeneOntologyBiologicalProcesspositive regulation of dendrite development

EZH2 PTPRZ1 COBL

6.68e-04221633GO:1900006
GeneOntologyBiologicalProcessregulation of postsynapse organization

PPFIA2 LRRK2 GRID1 TAOK2 IL1RAPL1 NF1 AFDN

6.85e-041851637GO:0099175
GeneOntologyBiologicalProcessregulation of small molecule metabolic process

TREX1 TCF7L2 ACADVL UBR4 CYP27B1 SIK1 IRS1 NCOR1 PRKAA2 PRKG1 DKKL1

6.91e-0443416311GO:0062012
GeneOntologyBiologicalProcessnegative regulation of striated muscle cell differentiation

TRIM72 DAXX EZH2 NOTCH1

7.03e-04511634GO:0051154
GeneOntologyBiologicalProcessgliogenesis

TCF7L2 MAPT EZH2 ITGB4 TTBK1 NF1 PTPRZ1 AFDN IL33 NOTCH1 SOS1

7.04e-0443516311GO:0042063
GeneOntologyBiologicalProcessregulation of neural precursor cell proliferation

LRRK2 SLC6A4 NF1 PTPRZ1 AFDN NOTCH1

7.21e-041351636GO:2000177
GeneOntologyBiologicalProcesssynaptic signaling

DMXL2 INSYN1 TSPOAP1 MAPT PPFIA2 LRRK2 PCDHB8 GRID1 NR4A1 EZH2 GRM5 SLC6A4 IL1RAPL1 NF1 KCNK3 AFDN BRSK1 NOTCH1

7.30e-0497616318GO:0099536
GeneOntologyBiologicalProcessregulation of lipid biosynthetic process

TREX1 TCF7L2 ACADVL UBR4 CYP27B1 SIK1 PRKG1 DKKL1

7.76e-042461638GO:0046890
GeneOntologyBiologicalProcessregulation of ketone metabolic process

TREX1 ACADVL UBR4 IRS1 NCOR1 PRKG1 DKKL1

7.77e-041891637GO:0010565
GeneOntologyBiologicalProcessnegative regulation of lipid biosynthetic process

ACADVL UBR4 CYP27B1 SIK1 DKKL1

7.80e-04911635GO:0051055
GeneOntologyBiologicalProcesssynapse assembly

EPHB3 SDK2 MYCBP2 MAPT PCDHB8 SYNDIG1 IL1RAPL1 AFDN SLITRK6

7.90e-043081639GO:0007416
GeneOntologyBiologicalProcessskin development

TCF7L2 CYP27B1 EZH2 FOXI3 ITGB4 NCOR1 NF1 EPHA2 NOTCH1 SOS1

7.90e-0437316310GO:0043588
GeneOntologyBiologicalProcesslearning or memory

MAPT GRM5 GRPR SLC6A4 TTBK1 NF1 PTPRZ1 CSMD1 BRSK1 NDRG4

7.90e-0437316310GO:0007611
GeneOntologyBiologicalProcessregulation of neurogenesis

MAPT EZH2 GRM5 IL1RAPL1 TTBK1 NF1 PTPRZ1 HEY2 AFDN IL33 PLXNA2 NOTCH1

8.30e-0451516312GO:0050767
GeneOntologyBiologicalProcesspositive regulation of neuron projection development

MAPT EZH2 IL1RAPL1 NF1 PTPRZ1 COBL AFDN NDRG4

8.40e-042491638GO:0010976
GeneOntologyBiologicalProcesschordate embryonic development

TBX3 TCF7L2 DYNC2I1 FOXI3 BIRC6 HOXA9 NCOR1 FOXD3 NF1 EPHA2 HEY2 COBL DMBT1 HECTD1 HCFC1 PLXNA2 NOTCH1

8.51e-0490616317GO:0043009
GeneOntologyBiologicalProcessmaintenance of gastrointestinal epithelium

VSIG1 MUC4 MUC6

8.68e-04241633GO:0030277
GeneOntologyBiologicalProcessnotochord development

GLI1 EPHA2 COBL

8.68e-04241633GO:0030903
GeneOntologyBiologicalProcessmacrophage activation

TREX1 MAPT LRRK2 MUC5B TTBK1 IL33

8.72e-041401636GO:0042116
GeneOntologyBiologicalProcesspostsynapse organization

EPHB3 INSYN1 PPFIA2 LRRK2 GRID1 TAOK2 IL1RAPL1 NF1 AFDN

8.85e-043131639GO:0099173
GeneOntologyBiologicalProcessconditioned place preference

SLC6A4 CSMD1

9.12e-0461632GO:1990708
GeneOntologyBiologicalProcessarterial endothelial cell differentiation

HEY2 NOTCH1

9.12e-0461632GO:0060842
GeneOntologyBiologicalProcessepidermal cell fate specification

FOXI3 NOTCH1

9.12e-0461632GO:0009957
GeneOntologyBiologicalProcessregulation of myotube differentiation

TRIM72 SIK1 DAXX NOTCH1

9.37e-04551634GO:0010830
GeneOntologyBiologicalProcessdendrite morphogenesis

EPHB3 PPFIA2 LRRK2 TAOK2 IL1RAPL1 PTPRZ1 AFDN

1.02e-031981637GO:0048813
GeneOntologyBiologicalProcessnegative regulation of lipid metabolic process

ACADVL UBR4 CYP27B1 SIK1 NCOR1 DKKL1

1.05e-031451636GO:0045833
GeneOntologyBiologicalProcessregulation of muscle cell differentiation

TRIM72 SIK1 DAXX EZH2 EPC1 HEY2 NOTCH1

1.05e-031991637GO:0051147
GeneOntologyBiologicalProcesstrabecula morphogenesis

CYP27B1 HEY2 NOTCH1 SOS1

1.07e-03571634GO:0061383
GeneOntologyBiologicalProcesslymphoid progenitor cell differentiation

TREX1 NOTCH1 SOS1

1.10e-03261633GO:0002320
GeneOntologyBiologicalProcessembryo development ending in birth or egg hatching

TBX3 TCF7L2 DYNC2I1 FOXI3 BIRC6 HOXA9 NCOR1 FOXD3 NF1 EPHA2 HEY2 COBL DMBT1 HECTD1 HCFC1 PLXNA2 NOTCH1

1.12e-0392916317GO:0009792
GeneOntologyBiologicalProcessstriated muscle cell differentiation

TRIM72 TBX3 SIK1 DAXX EZH2 SLC9A1 EPC1 HEY2 PRKG1 NOTCH1

1.13e-0339116310GO:0051146
GeneOntologyBiologicalProcessanterograde trans-synaptic signaling

DMXL2 INSYN1 TSPOAP1 MAPT PPFIA2 LRRK2 PCDHB8 GRID1 NR4A1 EZH2 GRM5 SLC6A4 NF1 KCNK3 AFDN BRSK1 NOTCH1

1.15e-0393116317GO:0098916
GeneOntologyBiologicalProcesschemical synaptic transmission

DMXL2 INSYN1 TSPOAP1 MAPT PPFIA2 LRRK2 PCDHB8 GRID1 NR4A1 EZH2 GRM5 SLC6A4 NF1 KCNK3 AFDN BRSK1 NOTCH1

1.15e-0393116317GO:0007268
GeneOntologyBiologicalProcessneural tube development

TCF7L2 NF1 EPHA2 COBL HECTD1 PLXNA2 NOTCH1

1.15e-032021637GO:0021915
GeneOntologyBiologicalProcesscardiac muscle tissue development

TREX1 TBX3 SIK1 SLC9A1 GLI1 HEY2 PRKG1 NDRG4 NOTCH1

1.20e-033271639GO:0048738
GeneOntologyBiologicalProcesseye morphogenesis

SDK2 FAT3 SHROOM2 NF1 ALMS1 EPHA2 NOTCH1

1.21e-032041637GO:0048592
GeneOntologyBiologicalProcessmicroglial cell activation

MAPT LRRK2 TTBK1 IL33

1.22e-03591634GO:0001774
GeneOntologyBiologicalProcessdigestive tract morphogenesis

EPHB3 TCF7L2 GLI1 NOTCH1

1.22e-03591634GO:0048546
GeneOntologyCellularComponentGolgi lumen

MUC16 MUC5B MUC12 MUC17 MUC3A MUC4 MUC6

2.45e-051091647GO:0005796
GeneOntologyCellularComponentpostsynaptic density membrane

GRID1 SYNDIG1 GRM5 IL1RAPL1 PTPRZ1 AFDN NOTCH1

2.45e-041571647GO:0098839
GeneOntologyCellularComponentsomatodendritic compartment

EPHB3 MAPT MARK3 PPFIA2 FAT3 LRRK2 SYNDIG1 GRM5 SHROOM2 TAOK2 IL1RAPL1 TTBK1 NF1 PTPRZ1 SCN1A PRKAA2 COBL AFDN HCFC1 INPP5J SOS1

6.38e-04122816421GO:0036477
GeneOntologyCellularComponentaxon

MYCBP2 TSPOAP1 PCDHGB1 MAPT PPFIA2 LRRK2 TAOK2 IL1RAPL1 NF1 PTPRZ1 SCN1A PRKAA2 COBL AFDN BRSK1 HCFC1 INPP5J

6.55e-0489116417GO:0030424
GeneOntologyCellularComponentextracellular matrix

COL4A1 COL7A1 MUC5B MMP20 ITGB4 LRIG1 MUC17 PTPRZ1 DMBT1 MUC4 MUC6 HCFC1 PLXNA2 OTOG

6.83e-0465616414GO:0031012
GeneOntologyCellularComponentexternal encapsulating structure

COL4A1 COL7A1 MUC5B MMP20 ITGB4 LRIG1 MUC17 PTPRZ1 DMBT1 MUC4 MUC6 HCFC1 PLXNA2 OTOG

7.04e-0465816414GO:0030312
DomainSEA

MUC16 MUC12 UMODL1 MUC17 MUC3A

1.33e-06231615PS50024
DomainSEA_dom

MUC16 MUC12 UMODL1 MUC17 MUC3A

1.33e-06231615IPR000082
DomainUBA

MARK3 USP24 SIK1 UBASH3A BRSK1 RAD23B

2.01e-06441616IPR015940
DomainUBA

MARK3 USP24 SIK1 UBASH3A BRSK1 RAD23B

3.00e-06471616PS50030
DomainVWF_type-D

MUC5B MUC4 MUC6 OTOG

8.93e-06161614IPR001846
DomainVWFD

MUC5B MUC4 MUC6 OTOG

8.93e-06161614PS51233
DomainVWD

MUC5B MUC4 MUC6 OTOG

8.93e-06161614SM00216
DomainVWD

MUC5B MUC4 MUC6 OTOG

8.93e-06161614PF00094
DomainFN3

EPHB3 COL7A1 SDK2 TSPOAP1 ITGB4 UMODL1 PTPRZ1 EPHA2 HCFC1

3.31e-051851619SM00060
DomainSEA

MUC16 MUC12 UMODL1 MUC17

3.45e-05221614PF01390
DomainFN3

EPHB3 COL7A1 SDK2 TSPOAP1 ITGB4 UMODL1 PTPRZ1 EPHA2 HCFC1

5.85e-051991619PS50853
Domainfn3

EPHB3 COL7A1 SDK2 TSPOAP1 ITGB4 UMODL1 PTPRZ1 EPHA2

8.23e-051621618PF00041
DomainFN3_dom

EPHB3 COL7A1 SDK2 TSPOAP1 ITGB4 UMODL1 PTPRZ1 EPHA2 HCFC1

8.52e-052091619IPR003961
DomainEGF-like_CS

FAT4 FAT3 MUC12 ITGB4 UMODL1 MUC17 EPHA2 MUC3A MUC4 NOTCH1

9.13e-0526116110IPR013032
DomainEGF_2

FAT4 FAT3 MUC12 ITGB4 UMODL1 MUC17 EPHA2 MUC3A MUC4 NOTCH1

1.04e-0426516110PS01186
DomainC8

MUC5B MUC6 OTOG

1.31e-04121613PF08742
DomainTIL

MUC5B MUC6 OTOG

1.31e-04121613PF01826
DomainUnchr_dom_Cys-rich

MUC5B MUC6 OTOG

1.69e-04131613IPR014853
DomainC8

MUC5B MUC6 OTOG

1.69e-04131613SM00832
Domain-

EPHB3 COL7A1 SDK2 MYCBP2 TSPOAP1 VSIG1 ITGB4 IL1RAPL1 LRIG1 UMODL1 PTPRZ1 CD33 EPHA2 SIGLEC1 HCFC1 PLXNA2

2.02e-04663161162.60.40.10
DomainTIL_dom

MUC5B MUC6 OTOG

2.13e-04141613IPR002919
DomainSEA

MUC16 MUC17 MUC3A

2.13e-04141613SM00200
DomainKinase-like_dom

EPHB3 MARK3 LRRK2 SCYL1 SIK1 ACAD10 TAOK2 TTBK1 GUCY2F EPHA2 PRKAA2 PRKG1 BRSK1 SOS1

2.58e-0454216114IPR011009
DomainEGF_1

FAT4 FAT3 MUC12 ITGB4 UMODL1 MUC17 MUC3A MUC4 NOTCH1

3.77e-042551619PS00022
DomainIg-like_fold

EPHB3 COL7A1 SDK2 MYCBP2 TSPOAP1 VSIG1 ITGB4 IL1RAPL1 LRIG1 UMODL1 PTPRZ1 CD33 EPHA2 SIGLEC1 HCFC1 PLXNA2

4.06e-0470616116IPR013783
Domain-

EPHB3 MYCBP2 CUL9 EPHA2 HECTD1

4.19e-047316152.60.120.260
DomainVWC_out

MUC5B MUC6 OTOG

5.50e-04191613SM00215
DomainVWFA

COL7A1 ITGAE ITGB4 MDN1 CPNE7

7.15e-04821615PS50234
DomainARM-type_fold

NBEAL1 UBR4 LRRK2 USP24 SCYL1 CUL9 HEATR6 NF1 HECTD1 TBCD

7.34e-0433916110IPR016024
DomainVWA

COL7A1 ITGAE ITGB4 MDN1 CPNE7

7.98e-04841615SM00327
DomainQuino_amine_DH_bsu

LRRK2 WDR6 UTP4

8.58e-04221613IPR011044
DomainCT

MUC5B MUC6 OTOG

8.58e-04221613SM00041
DomainEGF_3

FAT4 FAT3 UMODL1 MUC17 MUC3A MUC4 NOTCH1 OTOG

1.01e-032351618PS50026
DomainProt_kinase_dom

EPHB3 MARK3 LRRK2 SCYL1 SIK1 TAOK2 TTBK1 GUCY2F EPHA2 PRKAA2 PRKG1 BRSK1

1.11e-0348916112IPR000719
DomaintRNA-bd_arm

PPFIA2 RPRD2 PRKG1

1.11e-03241613IPR010978
DomainQuinoprotein_ADH-like_supfam

DMXL2 PCDHGB1 WDR6 UTP4

1.12e-03531614IPR011047
DomainPROTEIN_KINASE_DOM

EPHB3 MARK3 LRRK2 SCYL1 SIK1 TAOK2 TTBK1 GUCY2F EPHA2 PRKAA2 PRKG1 BRSK1

1.19e-0349316112PS50011
DomainCys_knot_C

MUC5B MUC6 OTOG

1.26e-03251613IPR006207
DomainCTCK_2

MUC5B MUC6 OTOG

1.26e-03251613PS01225
DomainGalactose-bd-like

EPHB3 MYCBP2 CUL9 EPHA2 HECTD1

1.32e-03941615IPR008979
DomainEGF-like_dom

FAT4 FAT3 UMODL1 MUC17 MUC3A MUC4 NOTCH1 OTOG

1.45e-032491618IPR000742
DomainAPC_su10/DOC_dom

MYCBP2 CUL9

1.51e-0371612IPR004939
DomainDOC

MYCBP2 CUL9

1.51e-0371612PS51284
DomainKA1/Ssp2_C

MARK3 PRKAA2

1.51e-0371612IPR028375
DomainANAPC10

MYCBP2 CUL9

1.51e-0371612PF03256
DomainAPC10

MYCBP2 CUL9

1.51e-0371612SM01337
DomainVWF_A

COL7A1 ITGAE ITGB4 MDN1 CPNE7

1.67e-03991615IPR002035
DomainProtein_kinase_ATP_BS

EPHB3 MARK3 LRRK2 SIK1 TAOK2 TTBK1 EPHA2 PRKAA2 PRKG1 BRSK1

1.70e-0337916110IPR017441
DomainPkinase

MARK3 LRRK2 SCYL1 SIK1 TAOK2 TTBK1 GUCY2F PRKAA2 PRKG1 BRSK1

1.76e-0338116110PF00069
DomainUBA

MARK3 SIK1 RAD23B

2.15e-03301613SM00165
PathwayREACTOME_DEFECTIVE_GALNT3_CAUSES_HFTC

MUC16 MUC5B MUC12 MUC17 MUC3A MUC4 MUC6

4.36e-11161277M27410
PathwayREACTOME_DEFECTIVE_C1GALT1C1_CAUSES_TNPS

MUC16 MUC5B MUC12 MUC17 MUC3A MUC4 MUC6

7.36e-11171277M27412
PathwayREACTOME_TERMINATION_OF_O_GLYCAN_BIOSYNTHESIS

MUC16 MUC5B MUC12 MUC17 MUC3A MUC4 MUC6

8.87e-10231277M556
PathwayREACTOME_DECTIN_2_FAMILY

MUC16 MUC5B MUC12 MUC17 MUC3A MUC4 MUC6

2.33e-09261277M27483
PathwayREACTOME_O_LINKED_GLYCOSYLATION_OF_MUCINS

B3GNT4 MUC16 MUC5B MUC12 MUC17 MUC3A MUC4 MUC6

7.82e-08621278M546
PathwayREACTOME_DISEASES_ASSOCIATED_WITH_O_GLYCOSYLATION_OF_PROTEINS

MUC16 MUC5B MUC12 MUC17 MUC3A MUC4 MUC6 NOTCH1

1.63e-07681278M27303
PathwayREACTOME_TERMINATION_OF_O_GLYCAN_BIOSYNTHESIS

MUC16 MUC5B MUC17 MUC4 MUC6

9.94e-07211275MM15706
PathwayREACTOME_O_LINKED_GLYCOSYLATION

B3GNT4 MUC16 MUC5B MUC12 MUC17 MUC3A MUC4 MUC6

7.06e-061111278M27416
PathwayREACTOME_O_LINKED_GLYCOSYLATION_OF_MUCINS

B3GNT4 MUC16 MUC5B MUC17 MUC4 MUC6

1.60e-05601276MM15636
PathwayREACTOME_DISEASES_OF_SIGNAL_TRANSDUCTION_BY_GROWTH_FACTOR_RECEPTORS_AND_SECOND_MESSENGERS

TCF7L2 AMER1 MARK3 FRS3 IRS1 SEC31A NR4A1 BIRC6 NCOR1 KANK1 NF1 DUSP16 HEY2 NOTCH1 SOS1

1.83e-0546412715M27547
PathwayREACTOME_DISEASES_OF_GLYCOSYLATION

MUC16 MUC5B MUC12 MUC17 MUC3A MUC4 MUC6 NOTCH1

4.47e-051431278M27275
PathwayREACTOME_C_TYPE_LECTIN_RECEPTORS_CLRS

MUC16 MUC5B MUC12 MUC17 MUC3A MUC4 MUC6

2.72e-041401277M27484
Pubmed

Mucin gene expression in human laryngeal epithelia: effect of laryngopharyngeal reflux.

MUC16 MUC5B MUC12 MUC17 MUC3A MUC4 MUC6

1.65e-1218168718834073
Pubmed

A central chaperone-like role for 14-3-3 proteins in human cells.

PRPF31 AMER1 MYCBP2 MAPT MARK3 SIK1 IRS1 CDC14A ESYT2 CCDC88A NF1 MDN1 ALMS1 MTUS1 PRKAA2 NCOA7 COBL AFDN USP54 HECTD1 FGD6 OTOG VCPIP1

3.49e-118611682336931259
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

PALD1 MYCBP2 TMEM94 UBR4 CUL9 GRID1 IRS1 BIRC6 ITGB4 C8orf58 TAOK2 KANSL3 NCOR1 EPS15L1 MDN1 EIF4ENIF1 GLI1 DUSP16 COBL HECTD1 HCFC1 NOTCH1 TBCD

4.28e-0911051682335748872
Pubmed

Pro-prion, as a membrane adaptor protein for E3 ligase c-Cbl, facilitates the ubiquitination of IGF-1R, promoting melanoma metastasis.

DMXL2 ACADVL NBEAL1 UBR4 ACAD10 ZNF362 SEC31A LPIN1 NCOR1 ESYT2 EPS15L1 KANK1 MDN1 RPRD2 FGD6 TBCD OTOG

4.71e-086891681736543142
Pubmed

STK11 is required for the normal program of ciliated cell differentiation in airways.

MARK3 SIK1 PRKAA2 BRSK1 NOTCH1

3.80e-0731168531636950
Pubmed

An antibody-based proximity labeling map reveals mechanisms of SARS-CoV-2 inhibition of antiviral immunity.

PALD1 PRPF31 MYCBP2 TMEM94 DYNC2I1 BIRC6 KANK1 CCDC88A EIF4ENIF1 ALMS1 WDR6 RPRD2 USP54 HECTD1 HCFC1 VCPIP1

6.10e-077331681634672954
Pubmed

Neuron-specific protein network mapping of autism risk genes identifies shared biological mechanisms and disease-relevant pathologies.

DMXL2 ACADVL MYCBP2 TSPOAP1 MAPT PPFIA2 UBR4 USP24 GRM5 SHROOM2 BIRC6 TAOK2 ESYT2 EPS15L1 CCDC88A NF1 SCN1A AFDN NDRG4 VCPIP1

7.06e-0711391682036417873
Pubmed

Interactomes of Glycogen Synthase Kinase-3 Isoforms.

ESYT2 CCDC88A EIF4ENIF1 ALMS1 MTUS1 EPHA2 COBL HECTD1 VCPIP1

8.91e-07209168936779422
Pubmed

Roles of tau protein in health and disease.

MAPT MARK3 TAOK2 TTBK1 BRSK1

1.42e-0640168528386764
Pubmed

Expression of Muc19/Smgc gene products during murine sublingual gland development: cytodifferentiation and maturation of salivary mucous cells.

MUC16 MUC5B MUC6

2.19e-066168319110483
Pubmed

Phosphorylation of microtubule-associated protein tau by AMPK-related kinases.

MAPT SIK1 BRSK1

2.19e-066168321985311
Pubmed

Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.

ZNF704 ABCC4 TCF7L2 AMER1 MYCBP2 PCDHGB1 MAPT MARK3 PPFIA2 DYNC2I1 ZNF362 SHROOM2 KANSL3 ESYT2 EPS15L1 PRKAA2 COBL RPRD2 CSMD1 HECTD1 TBCD CPNE7

3.25e-0614891682228611215
Pubmed

Tumor Architecture and Notch Signaling Modulate Drug Response in Basal Cell Carcinoma.

LRIG1 GLI1 NOTCH1

3.82e-067168329395868
Pubmed

Comparison of tear protein levels in breast cancer patients and healthy controls using a de novo proteomic approach.

COL7A1 DMXL2 LRRK2 DYNC2I1 CEP164 MTUS1 DMBT1

8.54e-06149168722664934
Pubmed

A large pool of actively cycling progenitors orchestrates self-renewal and injury repair of an ectodermal appendage.

LRIG1 GLI1 NOTCH1

9.10e-069168331481792
Pubmed

Prediction of the coding sequences of unidentified human genes. XV. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.

PALD1 GRID1 BIRC6 ESYT2 CCDC88A MTUS1

1.13e-05103168610574462
Pubmed

Selected reaction monitoring mass spectrometry reveals the dynamics of signaling through the GRB2 adaptor.

IRS1 EPS15L1 WDR6 AFDN FGD6 SOS1

1.13e-05103168621706016
Pubmed

CTDP1 regulates breast cancer survival and DNA repair through BRCT-specific interactions with FANCI.

SHROOM2 ESYT2 HEATR6 NF1 MDN1 TBCD

1.19e-05104168631240132
Pubmed

Polycomb-Mediated Repression and Sonic Hedgehog Signaling Interact to Regulate Merkel Cell Specification during Skin Development.

TCF7L2 EZH2 GLI1 DKKL1

1.93e-0533168427414999
Pubmed

Why do cellular proteins linked to K63-polyubiquitin chains not associate with proteasomes?

UBR4 MUC16 MUC5B CEP164 MDN1 OTOG RAD23B

2.01e-05170168723314748
Pubmed

The Functional Proximal Proteome of Oncogenic Ras Includes mTORC2.

TMEM94 MARK3 ESYT2 SLC9A1 NF1 EPHA2 COBL RELL1 SLITRK6 FGD6 PLXNA2 NOTCH1

2.29e-055691681230639242
Pubmed

The age at motor symptoms onset in LRRK2-associated Parkinson's disease is affected by a variation in the MAPT locus: a possible interaction.

MAPT LRRK2

2.32e-052168221898123
Pubmed

LRRK2 Promotes Tau Accumulation, Aggregation and Release.

MAPT LRRK2

2.32e-052168226014385
Pubmed

Notch-1 signaling activation sustains overexpression of interleukin 33 in the epithelium of nasal polyps.

IL33 NOTCH1

2.32e-052168230259982
Pubmed

Cognitive enhancement, TAU phosphorylation reduction, and neuronal protection by the treatment of an LRRK2 inhibitor in a tauopathy mouse model.

MAPT LRRK2

2.32e-052168233007689
Pubmed

Expression of mucins in mucoid otitis media.

MUC5B MUC4

2.32e-052168214690056
Pubmed

Horizontal transfer of the stemness-related markers EZH2 and GLI1 by neuroblastoma-derived extracellular vesicles in stromal cells.

EZH2 GLI1

2.32e-052168234217898
Pubmed

Protein kinase G dynamically modulates TASK1-mediated leak K+ currents in cholinergic neurons of the basal forebrain.

KCNK3 PRKG1

2.32e-052168220410120
Pubmed

Cep164, a novel centriole appendage protein required for primary cilium formation.

CEP164 ALMS1

2.32e-052168217954613
Pubmed

Notch1 intracellular domain increases cytoplasmic EZH2 levels during early megakaryopoiesis.

EZH2 NOTCH1

2.32e-052168222914328
Pubmed

Glutamate Delta-1 Receptor Regulates Metabotropic Glutamate Receptor 5 Signaling in the Hippocampus.

GRID1 GRM5

2.32e-052168227231330
Pubmed

EphA2 proteomics in human keratinocytes reveals a novel association with afadin and epidermal tight junctions.

EPHA2 AFDN

2.32e-052168227815408
Pubmed

LPIN1 promotes epithelial cell transformation and mammary tumourigenesis via enhancing insulin receptor substrate 1 stability.

IRS1 LPIN1

2.32e-052168227729374
Pubmed

Negative regulation of AMPK signaling by high glucose via E3 ubiquitin ligase MG53.

TRIM72 PRKAA2

2.32e-052168233400924
Pubmed

Physical interactions and functional coupling between Daxx and sodium hydrogen exchanger 1 in ischemic cell death.

DAXX SLC9A1

2.32e-052168218003619
Pubmed

MAPT IVS1+124 C>G modifies risk of LRRK2 G2385R for Parkinson's disease in Chinese individuals.

MAPT LRRK2

2.32e-052168224559644
Pubmed

Relationship between the expression of Notch1 and EZH2 and the prognosis of breast invasive ductal carcinoma.

EZH2 NOTCH1

2.32e-052168227050973
Pubmed

cGMP-dependent protein kinase Ialpha associates with the antidepressant-sensitive serotonin transporter and dictates rapid modulation of serotonin uptake.

SLC6A4 PRKG1

2.32e-052168219656393
Pubmed

HCF1 and OCT2 Cooperate with EBNA1 To Enhance OriP-Dependent Transcription and Episome Maintenance of Latent Epstein-Barr Virus.

POU2F2 HCFC1

2.32e-052168227009953
Pubmed

Orphan nuclear receptor TR3/Nur77 improves wound healing by upregulating the expression of integrin β4.

NR4A1 ITGB4

2.32e-052168225326539
Pubmed

Unraveling a novel transcription factor code determining the human arterial-specific endothelial cell signature.

HEY2 NOTCH1

2.32e-052168224108462
Pubmed

Biochemical characterization of TRIM72 E3 ligase and its interaction with the insulin receptor substrate 1.

TRIM72 IRS1

2.32e-052168232055715
Pubmed

An MG53-IRS1-interaction disruptor ameliorates insulin resistance.

TRIM72 IRS1

2.32e-052168229884820
Pubmed

Immunocytochemistry for MUC4 and MUC16 is a useful adjunct in the diagnosis of pancreatic adenocarcinoma on fine-needle aspiration cytology.

MUC16 MUC4

2.32e-052168223544943
Pubmed

LRRK2 phosphorylates novel tau epitopes and promotes tauopathy.

MAPT LRRK2

2.32e-052168224113872
Pubmed

HECTD1-Mediated Ubiquitination and Degradation of Rubicon Regulates Autophagy and Osteoarthritis Pathogenesis.

HECTD1 RUBCN

2.32e-052168236121967
Pubmed

The alarmin IL-33 is a notch target in quiescent endothelial cells.

IL33 NOTCH1

2.32e-052168222809957
Pubmed

Tau-tubulin kinase 1 enhances prefibrillar tau aggregation and motor neuron degeneration in P301L FTDP-17 tau-mutant mice.

MAPT TTBK1

2.32e-052168220354135
Pubmed

Acute inhibition of the CNS-specific kinase TTBK1 significantly lowers tau phosphorylation at several disease relevant sites.

MAPT TTBK1

2.32e-052168232255788
Pubmed

Immunohistochemical expression profiles of mucin antigens in salivary gland mucoepidermoid carcinoma: MUC4- and MUC6-negative expression predicts a shortened survival in the early postoperative phase.

MUC4 MUC6

2.32e-052168228649694
Pubmed

Large-scale characterization of HeLa cell nuclear phosphoproteins.

MYCBP2 MAPT USP24 DAXX EZH2 KANSL3 NCOR1 ESYT2 EPS15L1 NF1 MDN1 AFDN VCPIP1 SOS1

2.60e-057741681415302935
Pubmed

Transcriptome characterization elucidates signaling networks that control human ES cell growth and differentiation.

COL4A1 PALD1 PRPF31 ABCC4 MYCBP2 TMEM94 FAT3 LRRK2 USP24 DELE1 EZH2 TAOK2 NF1 EPC1 MARF1 USP54 RUBCN NOTCH1

2.62e-0512151681815146197
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

PALD1 TSPOAP1 TMEM94 MARK3 CUL9 KANK1 COBL RUBCN PLXNA2 VCPIP1

3.14e-054071681012693553
Pubmed

Substrate trapping proteomics reveals targets of the βTrCP2/FBXW11 ubiquitin ligase.

ZNF704 AMER1 EZH2 LPIN1 USP54 HCFC1

3.87e-05128168625332235
Pubmed

Novel HIV-1 knockdown targets identified by an enriched kinases/phosphatases shRNA library using a long-term iterative screen in Jurkat T-cells.

PPFIA2 EZH2 RAD23B

3.88e-0514168320174665
Pubmed

Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.

MYCBP2 UBR4 USP24 BIRC6 NCOR1 CCDC88A EIF4ENIF1 ALMS1 WDR6 VCPIP1

3.94e-054181681034709266
Pubmed

A BioID-Derived Proximity Interactome for SARS-CoV-2 Proteins.

ABCC4 TMEM94 SEC31A BIRC6 EPS15L1 SLC9A1 CCDC88A WDR6 NCOA7 COBL AFDN FGD6 TBCD

5.11e-057191681335337019
Pubmed

Impaired OTUD7A-dependent Ankyrin regulation mediates neuronal dysfunction in mouse and human models of the 15q13.3 microdeletion syndrome.

SDK2 FRS3 GRID1 IL1RAPL1 CCDC88A SCN1A AFDN

5.15e-05197168736604605
Pubmed

A protein network map of head and neck cancer reveals PIK3CA mutant drug sensitivity.

CUL9 IRS1 TNS4 SOS1 RAD23B

5.62e-0584168534591642
Pubmed

An essential role for Notch in neural crest during cardiovascular development and smooth muscle differentiation.

HEY2 PLXNA2 NOTCH1

5.92e-0516168317273555
Pubmed

Control of sinus venous valve and sinoatrial node development by endocardial NOTCH1.

TBX3 HEY2 NOTCH1

5.92e-0516168331591643
Pubmed

Transcriptome of the inner circular smooth muscle of the developing mouse intestine: Evidence for regulation of visceral smooth muscle genes by the hedgehog target gene, cJun.

MAPT HOXA9 NF1 LRIG1 GLI1 PRKG1

6.39e-05140168626930384
Pubmed

Protein interaction network of the mammalian Hippo pathway reveals mechanisms of kinase-phosphatase interactions.

AMER1 MARK3 BIRC6 NF1 EIF4ENIF1 ALMS1 AFDN USP54 HECTD1 NOTCH1

6.75e-054461681024255178
Pubmed

Microbial products alter the expression of membrane-associated mucin and antimicrobial peptides in a three-dimensional human endocervical epithelial cell model.

MUC16 MUC4

6.94e-053168223053434
Pubmed

Secretory carcinoma of breast: pattern of MUC 2/MUC 4/MUC 6 expression.

MUC4 MUC6

6.94e-053168223305535
Pubmed

Pathogenic Epigenetic Consequences of Genetic Alterations in IDH-Wild-Type Diffuse Astrocytic Gliomas.

EZH2 NF1

6.94e-053168231431463
Pubmed

LRRK2 phosphorylates tubulin-associated tau but not the free molecule: LRRK2-mediated regulation of the tau-tubulin association and neurite outgrowth.

MAPT LRRK2

6.94e-053168222303461
Pubmed

Cutting Edge: Codeletion of the Ras GTPase-Activating Proteins (RasGAPs) Neurofibromin 1 and p120 RasGAP in T Cells Results in the Development of T Cell Acute Lymphoblastic Leukemia.

NF1 NOTCH1

6.94e-053168226002977
Pubmed

mGlu5 in GABAergic neurons modulates spontaneous and psychostimulant-induced locomotor activity.

MAPT GRM5

6.94e-053168231646346
Pubmed

LRRK2 Facilitates tau Phosphorylation through Strong Interaction with tau and cdk5.

MAPT LRRK2

6.94e-053168226268594
Pubmed

Expression of the transmembrane mucins, MUC1, MUC4 and MUC16, in normal endometrium and in endometriosis.

MUC16 MUC4

6.94e-053168224939955
Pubmed

Interleukin-33 induces mucin gene expression and goblet cell hyperplasia in human nasal epithelial cells.

MUC5B IL33

6.94e-053168227776277
Pubmed

Regulation of membrane-associated mucins in the human corneal epithelial cells by dexamethasone.

MUC16 MUC4

6.94e-053168217592322
Pubmed

Phosphorylation of EZH2 by AMPK Suppresses PRC2 Methyltransferase Activity and Oncogenic Function.

EZH2 PRKAA2

6.94e-053168229351847
Pubmed

Requirement of brain interleukin33 for aquaporin4 expression in astrocytes and glymphatic drainage of abnormal tau.

MAPT IL33

6.94e-053168233432186
Pubmed

Prostate-derived sterile 20-like kinases (PSKs/TAOKs) phosphorylate tau protein and are activated in tangle-bearing neurons in Alzheimer disease.

MAPT TAOK2

6.94e-053168223585562
Pubmed

Genome-wide bidirectional CRISPR screens identify mucins as host factors modulating SARS-CoV-2 infection.

MUC16 MUC4

6.94e-053168235879412
Pubmed

PDCD2 is a negative regulator of HCF-1 (C1).

NCOR1 HCFC1

6.94e-053168212149646
Pubmed

Genetic susceptibility loci, environmental exposures, and Parkinson's disease: a case-control study of gene-environment interactions.

MAPT LRRK2

6.94e-053168223507417
Pubmed

Integrative analysis of the cancer genome atlas and cancer cell lines encyclopedia large-scale genomic databases: MUC4/MUC16/MUC20 signature is associated with poor survival in human carcinomas.

MUC16 MUC4

6.94e-053168230236127
Pubmed

Plexins promote Hedgehog signaling through their cytoplasmic GAP activity.

GLI1 PLXNA2

6.94e-053168236169302
Pubmed

Tau-tubulin kinase 1 (TTBK1), a neuron-specific tau kinase candidate, is involved in tau phosphorylation and aggregation.

MAPT TTBK1

6.94e-053168216923168
Pubmed

Differential Expression of MUC12, MUC16, and MUC20 in Patients with Active and Remission Ulcerative Colitis.

MUC16 MUC12

6.94e-053168226770020
Pubmed

Genomic organization and structure of the 3' region of human MUC3: alternative splicing predicts membrane-bound and soluble forms of the mucin.

MUC17 MUC3A

6.94e-053168210512748
Pubmed

TDP-43 pathology in a patient carrying G2019S LRRK2 mutation and a novel p.Q124E MAPT.

MAPT LRRK2

6.94e-053168223664753
Pubmed

Daxx positively modulates beta-catenin/TCF4-mediated transcriptional potential.

TCF7L2 DAXX

6.94e-053168219563778
Pubmed

Do interactions between SNCA, MAPT, and LRRK2 genes contribute to Parkinson's disease susceptibility?

MAPT LRRK2

6.94e-053168221816655
Pubmed

Functional Consequences of Differential O-glycosylation of MUC1, MUC4, and MUC16 (Downstream Effects on Signaling).

MUC16 MUC4

6.94e-053168227483328
Pubmed

MicroRNA-200c modulates the expression of MUC4 and MUC16 by directly targeting their coding sequences in human pancreatic cancer.

MUC16 MUC4

6.94e-053168224204560
Pubmed

Aberrant expression of mucin core proteins and o-linked glycans associated with progression of pancreatic cancer.

MUC4 MUC6

6.94e-053168223446997
Pubmed

Collagen mRNA levels changes during colorectal cancer carcinogenesis.

COL4A1 COL7A1

6.94e-053168219422682
Pubmed

GLI1, CTNNB1 and NOTCH1 protein expression in a thymic epithelial malignancy tissue microarray.

GLI1 NOTCH1

6.94e-053168225667444
Pubmed

Targeting EZH2 regulates the biological characteristics of glioma stem cells via the Notch1 pathway.

EZH2 NOTCH1

6.94e-053168237644332
Pubmed

DUSP28 links regulation of Mucin 5B and Mucin 16 to migration and survival of AsPC-1 human pancreatic cancer cells.

MUC16 MUC5B

6.94e-053168227230679
Pubmed

Physiological and functional interactions between Tcf4 and Daxx in colon cancer cells.

TCF7L2 DAXX

6.94e-053168216569639
Pubmed

Lrrk promotes tau neurotoxicity through dysregulation of actin and mitochondrial dynamics.

MAPT LRRK2

6.94e-053168230571694
Pubmed

Two atypical enteropathogenic Escherichia coli strains induce the production of secreted and membrane-bound mucins to benefit their own growth at the apical surface of human mucin-secreting intestinal HT29-MTX cells.

MUC17 MUC4

6.94e-053168220065027
Pubmed

Lack of exacerbation of neurodegeneration in a double transgenic mouse model of mutant LRRK2 and tau.

MAPT LRRK2

6.94e-053168225804954
Pubmed

Tumor necrosis factor (TNF)-α-induced repression of GKAP42 protein levels through cGMP-dependent kinase (cGK)-Iα causes insulin resistance in 3T3-L1 adipocytes.

IRS1 PRKG1

6.94e-053168225586176
Pubmed

Mechanisms of LRRK2-dependent neurodegeneration: role of enzymatic activity and protein aggregation.

MAPT LRRK2

6.94e-053168228202670
InteractionYWHAG interactions

AMER1 MYCBP2 MAPT MARK3 LRRK2 USP24 SIK1 IRS1 EZH2 SHROOM2 CDC14A TAOK2 SLC6A4 LPIN1 ESYT2 KANK1 TTBK1 CCDC88A NF1 MDN1 ALMS1 MTUS1 DUSP16 KCNK3 COBL AFDN USP54 HECTD1 FGD6 RUBCN OTOG

2.20e-08124816431int:YWHAG
InteractionYWHAH interactions

AMER1 MYCBP2 MAPT MARK3 LRRK2 SIK1 IRS1 CDC14A ESYT2 KANK1 CCDC88A NF1 ALMS1 MTUS1 DUSP16 PRKAA2 KCNK3 NCOA7 COBL AFDN USP54 HECTD1 FGD6 RUBCN OTOG VCPIP1

9.44e-07110216426int:YWHAH
InteractionPRNP interactions

DMXL2 ACADVL MAPT NBEAL1 UBR4 ACAD10 ZNF362 SEC31A GRM5 TAOK2 LPIN1 NCOR1 ESYT2 EPS15L1 KANK1 MDN1 PTPRZ1 UTP4 AFDN PIMREG RPRD2 FGD6 NDRG4 TBCD OTOG RAD23B

2.36e-06115816426int:PRNP
InteractionYWHAB interactions

PRPF31 MYCBP2 MAPT MARK3 LRRK2 SIK1 IRS1 EZH2 ITGB4 CDC14A SLC6A4 ESYT2 SLC9A1 KANK1 CCDC88A NF1 DUSP16 PRKAA2 KCNK3 AFDN USP54 HECTD1 FGD6 OTOG

2.47e-06101416424int:YWHAB
InteractionYWHAZ interactions

PRPF31 DMXL2 MYCBP2 MAPT MARK3 PPFIA2 LRRK2 SIK1 IRS1 NR4A1 EZH2 CDC14A NCOR1 SLC9A1 KANK1 CCDC88A NF1 MTUS1 DUSP16 PRKAA2 KCNK3 AFDN USP54 HECTD1 FGD6 RUBCN OTOG

8.20e-06131916427int:YWHAZ
InteractionYWHAE interactions

PRPF31 MYCBP2 MAPT MARK3 LRRK2 SIK1 IRS1 MMP20 EZH2 SHROOM2 CDC14A TAOK2 LPIN1 KANK1 CCDC88A NF1 DUSP16 KCNK3 AFDN PIMREG USP54 BRSK1 HECTD1 FGD6 RUBCN OTOG

1.01e-05125616426int:YWHAE
InteractionMARK2 interactions

MAPT MARK3 CDC14A SLC6A4 ESYT2 NF1 WDR6 GLI1 EPHA2 AFDN HECTD1

1.57e-0527416411int:MARK2
InteractionNUMB interactions

MAPT FRS3 IRS1 SLC6A4 ESYT2 EPS15L1 GLI1 EPHA2 AFDN NOTCH1

2.10e-0523216410int:NUMB
InteractionUSH1G interactions

PRPF31 DAXX NF1 PRKAA2

4.68e-05251644int:USH1G
GeneFamilyCD molecules|Mucins

MUC16 MUC5B MUC12 MUC17 MUC22 MUC3A MUC4 MUC6

2.56e-13211098648
GeneFamilyFibronectin type III domain containing

EPHB3 COL7A1 SDK2 TSPOAP1 ITGB4 PTPRZ1 EPHA2

5.21e-051601097555
GeneFamilyArmadillo repeat containing|Protein phosphatase 1 regulatory subunits

MAPT GRM5 NCOR1 SLC9A1 MARF1 CSMD1 HCFC1

1.13e-041811097694
GeneFamilyAcyl-CoA dehydrogenase family

ACADVL ACAD10

1.91e-03111092974
CoexpressionNABA_ECM_AFFILIATED

MUC16 MUC5B MUC12 MUC17 MUC22 MUC3A MUC4 MUC6 PLXNA2

1.53e-061701679M5880
CoexpressionGOBERT_OLIGODENDROCYTE_DIFFERENTIATION_DN

TCF7L2 MBOAT1 MAPT NBEAL1 TMEM94 NOXRED1 PCDHB8 SIK1 IRS1 SHROOM2 NCOR1 KANK1 TTBK1 ALMS1 LRIG1 PTPRZ1 MARF1 BRSK1 RUBCN NDRG4 NOTCH1 MXD1

2.94e-06112416722MM1070
CoexpressionGRYDER_PAX3FOXO1_TOP_ENHANCERS

COL4A1 PALD1 PGS1 TCF7L2 SIK1 ESYT2 KANK1 LRIG1 COBL PRKG1 PLXNA2 TBCD RAD23B

5.44e-0644116713M172
CoexpressionGSE20715_0H_VS_24H_OZONE_LUNG_DN

COL4A1 PGS1 LRRK2 EIF4ENIF1 EPHA2 DUSP16 IL33 PLXNA2 NOTCH1

5.80e-062001679M4367
CoexpressionBUSSLINGER_DUODENAL_MATURE_ENTEROCYTES

TBX3 ACADVL SLC13A2 ITGB4 CES2 SLC9A1 MUC17 AFDN INPP5J MXD1

6.78e-0625916710M40029
CoexpressionMANNO_MIDBRAIN_NEUROTYPES_HGABA

MYCBP2 TSPOAP1 PPFIA2 LRRK2 FRS3 POU2F2 GRID1 GRM5 SHROOM2 LPIN1 CCDC88A MDN1 MTUS1 SCN1A CELF3 PRKAA2 NCOA7 FRMPD3 SARDH CSMD1 NDRG4

8.02e-06110616721M39071
CoexpressionPEDRIOLI_MIR31_TARGETS_DN

MYCBP2 TSPOAP1 ITGB4 CDC14A SLC6A4 KANK1 MDN1 PSORS1C1 PRKAA2 AFDN CPNE7 VCPIP1

1.46e-0541316712M2494
CoexpressionGSE27241_WT_VS_RORGT_KO_TH17_POLARIZED_CD4_TCELL_TREATED_WITH_DIGOXIN_UP

NBEAL1 TMEM94 USP24 BIRC6 NCOR1 NF1 HCFC1 SOS1

2.12e-051801678M8239
CoexpressionGSE37301_CD4_TCELL_VS_GRANULOCYTE_MONOCYTE_PROGENITOR_DN

MBOAT1 TSPOAP1 ITGAE UBASH3A CDC14A LAX1 NF1 LRIG1

2.12e-051801678M8898
CoexpressionGOBERT_OLIGODENDROCYTE_DIFFERENTIATION_DN

TCF7L2 MBOAT1 MAPT NBEAL1 TMEM94 SIK1 IRS1 SHROOM2 NCOR1 KANK1 TTBK1 ALMS1 LRIG1 PTPRZ1 MARF1 BRSK1 RUBCN NDRG4 NOTCH1 MXD1

2.55e-05110216720M2369
CoexpressionBILD_HRAS_ONCOGENIC_SIGNATURE

TBX3 TCF7L2 CYP27B1 SLC9A1 MTUS1 EPHA2 TNS4 PLXNA2 MXD1

3.64e-052521679M12029
CoexpressionBUSSLINGER_GASTRIC_PREZYMOGENIC_CELLS

EPHB3 NBEAL1 PTPRZ1 MUC6 IL33

4.07e-05601675M40007
CoexpressionHALLMARK_MITOTIC_SPINDLE

SHROOM2 TAOK2 CCDC88A NF1 ALMS1 FGD6 TBCD SOS1

4.33e-051991678M5893
CoexpressionGSE8685_IL15_ACT_IL2_STARVED_VS_IL21_ACT_IL2_STARVED_CD4_TCELL_DN

PRPF31 CUL9 LCMT2 LPIN1 CCDC88A TNS4 DMBT1

7.74e-051601677M338
ToppCell3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.2.2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

COL7A1 MUC16 NR4A1 ITGB4 EPHA2 NCOA7 TNS4 MUC3A MUC4

2.19e-081741689207aa0118633cbe9a65839bbb1bb3ba9f8118ad2
ToppCellwk_15-18-Epithelial-Distal_epithelial_progenitor-epi-tip_intermediate|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

TRABD2A TSPOAP1 ZXDA LRIG1 MTUS1 EPHA2 PRKAA2 HCFC1 PLXNA2

3.72e-081851689636505a3d96f75d951ab42bcf8af6ae07abc732d
ToppCellnucseq-Epithelial-Epithelial_Alveolar|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

LRRK2 KANK1 MTUS1 SCN1A NCOA7 COBL AFDN PRKG1 USP54

5.60e-08194168953f3e49e91b1096f3226010e2de767efb490dfe4
ToppCell3'-Broncho-tracheal|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

COL7A1 ITGB4 PTPRZ1 EPHA2 NCOA7 TNS4 SLITRK6 MUC4 IL33

6.39e-0819716895d33f8a6940431093e927b186fb9b630a89d8ec1
ToppCell3'-Broncho-tracheal-Epithelial|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

COL7A1 ITGB4 PTPRZ1 EPHA2 NCOA7 TNS4 SLITRK6 MUC4 IL33

6.67e-081981689aa6e7218ee6230902854e66c444b544218b30c0e
ToppCellTracheal-NucSeq-Epithelial-Epi_airway_basal-Basal|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

COL7A1 ABCC4 ITGB4 PTPRZ1 TNS4 SLITRK6 CSMD1 MUC4 IL33

6.97e-08199168994a7867e800df352731796de8c24cba133c29622
ToppCellChildren_(3_yrs)-Epithelial-lung_goblet_cell-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

MUC16 MUC5B NR4A1 LRIG1 PTPRZ1 EPHA2 TNS4 MUC4

1.85e-0716116882d63b279d9a5132e1c09b03930bf9039036d24a2
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Neural-neural_cell-Schwann_Cell_/_Neural-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SLC25A18 DAXX UBASH3A ITGB4 IL1RAPL1 PTPRZ1 PSORS1C1 BRSK1

2.33e-071661688f742d15b02a6f651bbd00f53e3d871f40d05a03d
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Neural|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SLC25A18 DAXX UBASH3A ITGB4 IL1RAPL1 PTPRZ1 PSORS1C1 BRSK1

2.33e-0716616880f013bb5fdb72e88c2fc73d60cd01551a2db6341
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Neural-neural_cell-Schwann_Cell_/_Neural|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SLC25A18 DAXX UBASH3A ITGB4 IL1RAPL1 PTPRZ1 PSORS1C1 BRSK1

2.33e-071661688e941df9a1091164edde3def8fc7d410186b2bd88
ToppCellTCGA-Ovary-Primary_Tumor-Ovarian_Carcinoma-Serous_Cystadenocarcinoma-5|TCGA-Ovary / Sample_Type by Project: Shred V9

MBOAT1 USP24 ACAD10 WDR6 EPC1 AFDN RPRD2 TEX44

2.33e-07166168832d2eaf8a5d03881bf74d680825af2d5110b082d
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Neural-neural_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SLC25A18 DAXX UBASH3A ITGB4 IL1RAPL1 PTPRZ1 PSORS1C1 BRSK1

2.33e-071661688aeda46bea5d8463c24a83b98b9ed92d962d733e5
ToppCellPrimary_Motor_Cortex_(M1)-Non-neuronal-Macroglial-Astro-Astrocyte-Astro_L1_FGFR3_MT1G|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SLC25A18 ITGB4 CDC14A KANK1 LRIG1 RELL1 IL33 NOTCH1

3.06e-07172168855fba5ce0ead1114e1a76f67ad68432c6bac90e5
ToppCellnormal_Lung-T/NK_cells-Exhausted_Tfh|normal_Lung / Location, Cell class and cell subclass

TRABD2A MAPT EZH2 FOXI3 ITGAE UBASH3A TNS4 SARDH

3.20e-071731688e8ead6c51c41dbd43c717ba9d1a7a0ab39c79330
ToppCelldroplet-Bladder-BLADDER-1m-Epithelial-endothelial_cell|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MAPT FAT3 SYNDIG1 IRS1 FOXD3 PTPRZ1 PXYLP1 SLITRK6

4.15e-071791688c7c74e26bbf86c5326ee38bac7de111d5414f46b
ToppCellCOVID-19-Endothelial_cells-Capillary_endothelial_cells|COVID-19 / group, cell type (main and fine annotations)

COL4A1 PALD1 TBX3 SHROOM2 SLC6A4 PRKG1 NDRG4 PLXNA2

4.51e-071811688c5f9c92af1384d9089c65afdf41c6feb8345a3ae
ToppCellAdult-Epithelial-basal_cell|Adult / Lineage, Cell type, age group and donor

COL7A1 SDK2 ITGB4 PTPRZ1 EPHA2 TNS4 SLITRK6 IL33

4.91e-07183168800a6b19ca49e3b8e0d1cd387a3515b0ff4b81c81
ToppCellControl-Epithelial_cells-Airway_mucous|Control / group, cell type (main and fine annotations)

TCF7L2 MUC16 MUC5B ITGB4 MUC17 MUC3A MUC4 MXD1

4.91e-07183168815d24a4fb1ffe6cbafbd54fcd7dde9ddcfbe03b2
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FAT4 PPFIA2 FAT3 GRID1 MUC5B GUCY2F CSMD1 OTOG

5.11e-0718416882cbed6462fea2622871bb7e49b0df3d984239281
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FAT4 PPFIA2 FAT3 GRID1 MUC5B GUCY2F CSMD1 OTOG

5.11e-0718416882b19a8c5f823e00812908b23e66bb4e563278aff
ToppCell21-Trachea-Mesenchymal-Airway_Smooth_Muscle|Trachea / Age, Tissue, Lineage and Cell class

COL4A1 TBX3 PCDHB12 SYNDIG1 IRS1 KCNK3 PRKG1 DKKL1

5.11e-07184168886a96cd88e50eacad1f0badfbbf6dc626f41725e
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FAT4 PPFIA2 FAT3 GRID1 MUC5B GUCY2F CSMD1 OTOG

5.11e-071841688ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCellChildren_(3_yrs)-Endothelial-endothelial_cell_of_artery-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

FAT4 NR4A1 ITGB4 HEY2 CSMD1 IL33 NDRG4 PLXNA2

5.33e-071851688a7ae76058b2082020cadec49d63b9f4e24d21734
ToppCellAdult-Epithelial-alveolar_epithelial_cell_type_2-D175|Adult / Lineage, Cell type, age group and donor

ABCC4 LRRK2 KANK1 MTUS1 SCN1A DUSP16 NCOA7 DMBT1

6.02e-071881688ec38def1fdbb34ed9b30244806975bd5a4370164
ToppCellIPF-Epithelial-Basal|Epithelial / Disease state, Lineage and Cell class

COL7A1 SDK2 ITGB4 KANK1 PTPRZ1 TNS4 IL33 NOTCH1

6.52e-0719016884f15842b424eefadbfe451875e517cf70e29607f
ToppCellEpithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)|World / Lineage, Cell type, age group and donor

NBEAL1 LRRK2 KANK1 MTUS1 COBL AFDN USP54 PLXNA2

6.78e-071911688d3733c8c4bda70c4390e5601fdda6188a64be944
ToppCellnucseq-Epithelial|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

LRRK2 KANK1 MTUS1 NCOA7 COBL AFDN PRKG1 USP54

7.93e-0719516889406866f99555198a9be311fbd65751b70f35446
ToppCellCOVID-19-Epithelial-Club,_Basal_cells|COVID-19 / Condition, Lineage and Cell class

MUC16 MUC5B ITGB4 PTPRZ1 PRKAA2 SLITRK6 MUC4 IL33

8.24e-071961688dd32046067d93b9484cfbf1d7826a436a3d9f0e9
ToppCellBasal_cells-Myositis-ILD_01|World / lung cells shred on cell class, cell subclass, sample id

COL7A1 SDK2 IRS1 ITGB4 PTPRZ1 TNS4 SLITRK6 IL33

8.24e-0719616883b66f3a79b3f2ebacb4ad646f179e505ab38d6f0
ToppCellBronchial-NucSeq-Epithelial-Epi_airway_basal-Basal|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

COL7A1 ITGB4 PTPRZ1 EPHA2 TNS4 SLITRK6 MUC4 IL33

8.56e-0719716881e915957ea6a4550ecb9d6ee4b232aa5800faf20
ToppCell10x_3'_v3-tissue-resident_(10x_3'_v3)-myeloid-myeloid_monocytic-monocyte|tissue-resident_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

TBX3 NR4A1 ITGB4 FOXD3 PTPRZ1 HEY2 COBL SLITRK6

8.56e-071971688b2f4d7c301c0b24003374923b31d6d058e40b213
ToppCellAT2_cells-IPF_04|World / lung cells shred on cell class, cell subclass, sample id

ABCC4 LRRK2 SIK1 MUC5B NR4A1 MTUS1 SCN1A DMBT1

8.56e-071971688fd7bdfa6bf5966ebc11fdd13915769429540ddbf
ToppCellParenchymal-10x5prime-Epithelial-Epi_airway_basal|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

COL7A1 ITGB4 PTPRZ1 EPHA2 TNS4 SLITRK6 MUC4 IL33

8.56e-071971688de772bd2b4cda843777ac879b1087e6444199dfb
ToppCell3'-Broncho-tracheal-Epithelial-Airway_epithelium|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

COL7A1 ITGB4 PTPRZ1 EPHA2 NCOA7 TNS4 SLITRK6 IL33

8.89e-071981688240e1aa0594ee6de530b2f97d5e392c5fcbf278b
ToppCell3'-Broncho-tracheal-Epithelial-Airway_epithelium-respiratory_basal_cell|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

COL7A1 ITGB4 PTPRZ1 EPHA2 NCOA7 TNS4 SLITRK6 IL33

8.89e-0719816889a229167d4da4abf8c336dfe5cfdf57db756fc8b
ToppCellTracheal-NucSeq-Epithelial-Epi_airway_basal-Suprabasal|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

ABCC4 SIK1 PTPRZ1 EPHA2 TNS4 MUC4 IL33 NOTCH1

8.89e-07198168819d8ff3a4f911b13ecc34844202925475ad4d2ab
ToppCell3'-Broncho-tracheal-Epithelial-Airway_epithelium-respiratory_basal_cell-Basal_resting-Basal_resting_L.0.0.0.2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

COL7A1 IRS1 ITGB4 PTPRZ1 EPHA2 NCOA7 TNS4 IL33

8.89e-071981688fc00cb25cdc6c31b7f9d397bc9f9a8f4e9708003
ToppCell3'-Broncho-tracheal-Epithelial-Airway_epithelium-respiratory_basal_cell-Suprabasal-Suprabasal_L.0.0.2.3|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

COL7A1 ITGB4 PTPRZ1 EPHA2 NCOA7 TNS4 MUC4 IL33

8.89e-07198168822935a8afac54021f68b5f7a5accf51523e2f336
ToppCellTracheal-NucSeq-Epithelial-Epi_airway_basal|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

COL7A1 ABCC4 SIK1 PTPRZ1 EPHA2 TNS4 MUC4 IL33

8.89e-0719816885374b0e98d669f36a0571d3c006c7bd5e3c8e87f
ToppCell(02)_MMP9/10+-(1)_GFP|(02)_MMP9/10+ / shred by cell type by condition

COL4A1 COL7A1 ACADVL SIK1 DAXX MUC5B ITGB4 EPHA2

9.24e-071991688448ba982be804007f991d469eca9d885b21ae499
ToppCell3'-Broncho-tracheal-Epithelial-Airway_epithelium-respiratory_basal_cell-Suprabasal-Suprabasal_L.0.0.2.2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

COL7A1 ITGB4 PTPRZ1 EPHA2 NCOA7 TNS4 MUC4 IL33

9.24e-071991688c88a28a73f54dc571f2ff1e4b55073f83cbead2c
ToppCellLung_Parenchyma-Severe-Epithelial-Epithelial-Basal_3-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

COL7A1 ITGB4 PTPRZ1 EPHA2 NCOA7 TNS4 SLITRK6 IL33

9.59e-07200168841705bbba40eb5ddca0b223191aac1bce00163b8
ToppCellmild-HLA-DR+_CD83+_Monocyte|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

DMXL2 TCF7L2 LRRK2 POU2F2 CCDC88A SIGLEC1 FGD6 MXD1

9.59e-072001688934c2efc780318c66d667ca75be0de350361d351
ToppCell5'-GW_trimst-1.5-LargeIntestine-Neuronal|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TBX3 MAPT POU2F2 FOXD3 PTPRZ1 CELF3 NCOA7 NDRG4

9.59e-07200168851d20543a9c9330c34c085d9290a1fc8b5bff0d4
ToppCellBronchial-10x5prime-Epithelial-Epi_airway_basal|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

COL7A1 ITGB4 PTPRZ1 EPHA2 TNS4 SLITRK6 MUC4 IL33

9.59e-072001688afac850d5a40de0d6f02857cf81a19443d90b1eb
ToppCellParenchyma_COVID-19-Epithelial-TX-Basal_3|Parenchyma_COVID-19 / Sample group, Lineage and Cell type

COL7A1 ITGB4 PTPRZ1 EPHA2 NCOA7 TNS4 SLITRK6 IL33

9.59e-07200168853e04399d0308b40ae99fbfaa4ff62bf061822d8
ToppCellLung_Parenchyma-Severe-Epithelial-Epithelial-Basal_3|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)

COL7A1 ITGB4 PTPRZ1 EPHA2 NCOA7 TNS4 SLITRK6 IL33

9.59e-072001688cc8df398532c9324fd3e171000b1ea5c208cd691
ToppCellBronchial-10x5prime-Stromal-Peri/Epineurial_-NAF_endoneurial|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

COL4A1 PPFIA2 MUC5B MTUS1 GLI1 PXYLP1 USP54 CCDC171

9.59e-07200168829054cf55e88e1ac81a562d8dd9af9b7c749321d
ToppCellBronchial-10x5prime-Epithelial-Epi_airway_basal-Basal|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

COL7A1 ITGB4 PTPRZ1 EPHA2 TNS4 SLITRK6 MUC4 IL33

9.59e-0720016880594ca7bc313b73e1dc800cf058f8f798b0284cb
ToppCellCOVID-19_Mild|World / 5 Neutrophil clusters in COVID-19 patients

TSPOAP1 MAPT LRRK2 MARF1 SIGLEC1 CSMD1 CCDC158

1.83e-0615216872ff0980dfd8d430cca14649151d856edef115720
ToppCellASK428-Epithelial-Secretory|ASK428 / Donor, Lineage and Cell class of Lung cells from Dropseq

COL7A1 ITGB4 PTPRZ1 RUSC1-AS1 TNS4 MUC4 IL33

3.85e-0617016879e275c4a70f9866f770fbdb0fe14a577287fe290
ToppCelldroplet-Pancreas-Exocrine-21m-Epithelial-pancreatic_ductal_cel|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MBOAT1 FAT3 EZH2 UMODL1 PIMREG DKKL1 IL33

4.16e-061721687c0bda7153e02bee7d0326138cc684151c404c2a1
ToppCellAdult-Epithelial-basal_cell-D231|Adult / Lineage, Cell type, age group and donor

COL7A1 SDK2 ITGB4 PTPRZ1 TNS4 IL33 PLXNA2

4.49e-061741687a4f98afe7d1cc2617f6f7bc8092c41df57474b30
ToppCelldroplet-Lung-3m-Mesenchymal-myofibroblast-pericyte_cell|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ZNF704 COL7A1 MBOAT1 MAPT VSIG1 KCNK3 PRKG1

4.84e-061761687f931192e3cc65414e2245354f443473696cc7ce8
ToppCelldroplet-Lung-3m-Mesenchymal-myofibroblast-pericyte_cell-pericyte|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ZNF704 COL7A1 MBOAT1 MAPT VSIG1 KCNK3 PRKG1

4.84e-061761687e2b59a904c5c8f9c88e1e63788e9b6485f22edd0
ToppCellChildren_(3_yrs)-Epithelial-basal_cell|Children_(3_yrs) / Lineage, Cell type, age group and donor

COL7A1 ITGB4 LRIG1 PTPRZ1 TNS4 IL33 PLXNA2

5.21e-061781687fba2e38c05cbf031e0c6d47b1602575fea734a57
ToppCelldroplet-Heart-4Chambers-21m-Mesenchymal-nan|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PPFIA2 C8orf58 DGLUCY KANK1 LRIG1 GLI1 HEY2

5.40e-061791687b44e2d53b82c3c141bfc6539054b19708200a0d9
ToppCell3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.0.5|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MUC16 MUC5B NR4A1 EPHA2 PRKAA2 USP54 MUC4

5.40e-0617916876e965e424eebef50f0202cff75f458be395cfca1
ToppCell5'-Adult-Appendix-Mesenchymal-fibroblastic-Stromal_2_(NPY+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

B3GNT4 ABCC4 SLC25A18 SDK2 GRID1 IL1RAPL1 SLITRK6

5.40e-061791687a1ea8daa0fe8900f5a04b555c77fe8ebdaa3908d
ToppCellChildren_(3_yrs)-Mesenchymal-myofibroblast_cell|Children_(3_yrs) / Lineage, Cell type, age group and donor

COL4A1 TBX3 FAT4 SYNDIG1 IRS1 PRKG1 SLITRK6

5.61e-06180168701f2e5d96016823482f89ba503d007d4bd88eeac
ToppCelldroplet-Kidney-KIDNEY-30m-Epithelial-collecting_duct_principal_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

INSYN1 PCDHB12 ITGB4 IL1RAPL1 TTBK1 BRSK1 CCDC171

5.81e-0618116877af469f5bcb9b1ab3f35b2758bf2afb87e8eba57
ToppCellCOPD-Epithelial-Basal|World / Disease state, Lineage and Cell class

ITGB4 KANK1 EPHA2 COBL TNS4 MUC4 IL33

5.81e-0618116876d8a886b4afe729f8a05b9c0f4ea9375de735da4
ToppCellChildren_(3_yrs)-Mesenchymal-pericyte_cell-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

COL4A1 TBX3 GRID1 IRS1 SHROOM2 KCNK3 PRKG1

5.81e-061811687451b87ac95154bb80018b8dd245b4a6389d81411
ToppCellCOPD-Epithelial-Basal|COPD / Disease state, Lineage and Cell class

COL7A1 ITGB4 KANK1 EPHA2 TNS4 MUC4 IL33

6.25e-0618316870f760e393edc91009bf6c7e02eeac039a1dfb4ed
ToppCellPrimary_Motor_Cortex_(M1)-Non-neuronal-Macroglial-Astro-Astrocyte-Astro_L1_FGFR3_FOS|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SLC25A18 ITGB4 CDC14A KANK1 LRIG1 IL33 NOTCH1

6.47e-06184168722c18964818fc9c8f18051f836d718937b0d8d12
ToppCellCOPD-Epithelial-Goblet|World / Disease state, Lineage and Cell class

MUC16 MUC5B MTUS1 EPHA2 PRKAA2 COBL MUC4

6.95e-061861687d75fe7640a4b2c450c9759a1b3c3ef2a087f0092
ToppCellILEUM-inflamed-(8)_Fibroblast-(8)_Smooth_muscle_cells|(8)_Fibroblast / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

COL4A1 TBX3 SLC25A18 SDK2 UBASH3A MTUS1 GLI1

6.95e-061861687cacc2f0b2ed46516173b61ba1c5c226a2db7cddc
ToppCellTCGA-Pancreas-Primary_Tumor-Pancreatic_Adenocarcinoma-Ductal_Adenocarcinoma-1|TCGA-Pancreas / Sample_Type by Project: Shred V9

AMER1 NBEAL1 IRS1 BIRC6 ALMS1 MARF1 SOS1

6.95e-06186168703db813598b67b1e08f759758a1c2023396921fa
ToppCellAnterior_Cingulate_gyrus_(CgG)-Non-neuronal-Macroglial-Astro-Astrocyte|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SLC25A18 TCF7L2 ITGB4 CDC14A KANK1 LRIG1 NOTCH1

7.20e-061871687dd1d91f101b837bba513f77defa6e6902b2c0570
ToppCellAnterior_Cingulate_gyrus_(CgG)-Non-neuronal-Macroglial-Astro|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SLC25A18 TCF7L2 ITGB4 CDC14A KANK1 LRIG1 NOTCH1

7.20e-061871687ae90c263f80c36a410150d499e268d198944a3d9
ToppCell3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MUC16 MUC5B EPHA2 PRKAA2 NCOA7 DMBT1 MUC4

7.20e-06187168771d99a1a95d3692a2891da49d4a243bae6e07fd0
ToppCellCOVID-19-Epithelial_cells-Airway_basal|COVID-19 / group, cell type (main and fine annotations)

COL7A1 ITGB4 PTPRZ1 TNS4 SLITRK6 MUC4 PLXNA2

7.20e-0618716878407a82e98f56a94ea26562bcb6bbe00a8f41661
ToppCellFetal_29-31_weeks-Mesenchymal-pericyte_cell-D062|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

COL4A1 PALD1 TBX3 MAPT GRID1 SHROOM2 KCNK3

7.45e-061881687ccddc08121caff958a2b6f9e278a018858af6b4d
ToppCellAdult-Endothelial-alveolar_capillary_endothelial_cell_(Cap2;_aerocyte)|Adult / Lineage, Cell type, age group and donor

COL4A1 PALD1 TBX3 SLC6A4 IL1RAPL1 PRKG1 NDRG4

7.45e-061881687e5cad03f4a64147fe8174e7f614cf45233ffb9b7
ToppCellAdult-Endothelial-capillary_endothelial_cell_(Cap1)-D122|Adult / Lineage, Cell type, age group and donor

COL4A1 PALD1 TBX3 SHROOM2 SLC6A4 NDRG4 PLXNA2

7.45e-06188168702a62888e9db29d20133eeca1686d302545a39c9
ToppCellControl-Epithelial_cells|Control / group, cell type (main and fine annotations)

NBEAL1 LRRK2 KANK1 MTUS1 SCN1A COBL USP54

7.45e-061881687707ebf76cc6fb600b2f07793cf4ea9482c0de79d
ToppCellIPF-Endothelial-VE_Capillary_A|World / Disease state, Lineage and Cell class

COL4A1 PALD1 TBX3 SHROOM2 SLC6A4 PRKG1 NDRG4

7.71e-061891687ea3aa3ef38f1d405bb527ae383cd12c551a3dd6f
ToppCellCOVID-19-lung-Secretory|lung / Disease (COVID-19 only), tissue and cell type

MUC5B ITGB4 LRIG1 MTUS1 PTPRZ1 TNS4 MUC4

7.71e-06189168784d48e3ed25bebb8bb8074b3a2c5e2e88cff7f25
ToppCellIPF-Epithelial-Basal|IPF / Disease state, Lineage and Cell class

COL7A1 SDK2 ITGB4 KANK1 PTPRZ1 EPHA2 TNS4

7.98e-061901687ea19e9ce954f2dfde97388db9695325cd92ab88f
ToppCellControl-Epithelial-ATII|Control / Disease state, Lineage and Cell class

KANK1 MTUS1 EPHA2 COBL PRKG1 USP54 DMBT1

7.98e-061901687d50902a3abcc18aafa36d83cc2c6e07d7f7cb197
ToppCellIPF-Endothelial-VE_Capillary_A|IPF / Disease state, Lineage and Cell class

COL4A1 PALD1 TBX3 SHROOM2 SLC6A4 PRKG1 NDRG4

7.98e-061901687b4e35cbfe4d43d2cd51f29c3085e4d9b1012e6f0
ToppCellChildren_(3_yrs)-Endothelial-endothelial_cell_of_artery|Children_(3_yrs) / Lineage, Cell type, age group and donor

FAT4 NR4A1 ITGB4 HEY2 CSMD1 IL33 NDRG4

7.98e-061901687f6c38d197fd9d69a4f97cb2e72cd4747984c1a86
ToppCellCOVID-19-Epithelial_cells-Airway_goblet|COVID-19 / group, cell type (main and fine annotations)

MUC16 MUC5B MTUS1 PTPRZ1 PRKAA2 TNS4 MUC4

7.98e-06190168751ca9ef4df3220487152fcf684147730637c7cc1
ToppCellFetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_2-D150|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

ABCC4 LRRK2 NR4A1 KANK1 MTUS1 EPHA2 USP54

8.26e-06191168734cc997e4e5c727495f321e6807a84aa124da486
ToppCellChildren_(3_yrs)-Endothelial-alveolar_capillary_endothelial_cell_(Cap2;_aerocyte)|Children_(3_yrs) / Lineage, Cell type, age group and donor

PALD1 TBX3 FAT4 SLC6A4 IL1RAPL1 PRKG1 NDRG4

8.26e-061911687f229abf69a1217194f74b0502486907e07dba989
ToppCellBasal_cells-IPF_02|World / lung cells shred on cell class, cell subclass, sample id

COL7A1 SDK2 ITGB4 PTPRZ1 TNS4 SLITRK6 IL33

8.26e-061911687a98915bad9a4a61dd4cbca798914849b805f4a19
ToppCellIPF-Epithelial-Basal|World / Disease state, Lineage and Cell class

COL7A1 SDK2 ITGB4 KANK1 PTPRZ1 EPHA2 TNS4

8.55e-0619216879b91e0b162e6f3ce86dd15cc33c2e745d069581f
ToppCellAdult-Epithelial|Adult / Lineage, Cell type, age group and donor

LRRK2 KANK1 LRIG1 MTUS1 COBL PRKG1 USP54

8.55e-061921687efb962a5fd3b9bdfd8cf8d13c435e29c8271713e
ToppCellPrimary_Motor_Cortex_(M1)-Non-neuronal-Macroglial-Astro|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SLC25A18 ITGB4 CDC14A KANK1 LRIG1 PTPRZ1 NOTCH1

8.84e-06193168740edc07b6e7f19f6ee885fa5af0b63ef1b0f2468
ToppCell10x5'-GI_small-bowel|World / Manually curated celltypes from each tissue

TSPOAP1 MUC12 NR4A1 ITGAE MUC17 DMBT1 MUC3A

8.84e-061931687cd89dfe53a114078f06343049685883c8e26508f
ToppCellnucseq-Epithelial-Epithelial_Alveolar-AT2|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

ABCC4 LRRK2 KANK1 MTUS1 SCN1A NCOA7 DMBT1

8.84e-061931687f3cc7cfdbc164a4ed42f87647111522b7d393bcb
ToppCellnucseq-Epithelial-Epithelial_Alveolar-AT2-AT2|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

ABCC4 LRRK2 KANK1 MTUS1 SCN1A NCOA7 DMBT1

8.84e-061931687fd4d3c0d7caf8a2fff5b3d901fc28d19a8163cdf
ToppCellPrimary_Motor_Cortex_(M1)-Non-neuronal-Macroglial-Astro-Astrocyte|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SLC25A18 ITGB4 CDC14A KANK1 LRIG1 PTPRZ1 NOTCH1

8.84e-061931687b03d908d4b8940927f72c76a1b0f237d13f39056
ToppCellnucseq-Mesenchymal-Myocytic|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

COL4A1 COL7A1 PPFIA2 SYNDIG1 IRS1 KCNK3 PRKG1

9.14e-0619416872d66091097e106c7bee22e5281f50724700bdf8d
ToppCellBronchus_Control_(B.)-Epithelial-TX-AT2-2|Bronchus_Control_(B.) / Sample group, Lineage and Cell type

TRIM72 TBX3 COL7A1 AMER1 ZXDA EPHA2 TNS4

9.14e-0619416875bfc26668fa8f109f2ebc0d5fd98ab5bd219e62c
ToppCellfacs-Heart-RA-18m-Endothelial|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL4A1 TBX3 SIK1 TAOK2 AFDN PLXNA2 NOTCH1

9.46e-06195168730c75761079fa1e1a3b84d23c88a222f459d5ce5
ToppCellParenchymal-10x5prime-Epithelial-Epi_airway_basal-Basal|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

COL7A1 ITGB4 PTPRZ1 EPHA2 TNS4 SLITRK6 IL33

9.78e-061961687c5adab88140a465698abcbedc6505a43cae7bfd1
ToppCell3'-GW_trimst-2-LargeIntestine-Mesenchymal-fibroblastic-Stromal_1_(ADAMDEC1+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

FAT4 PPFIA2 SYNDIG1 HOXA9 GLI1 PRKG1 SLITRK6

9.78e-061961687a7adc0e0baef261d0937e4e8351321d41beca82f
ToppCellBronchial-NucSeq-Epithelial-Epi_submucosal-gland-Myoepithelial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

COL7A1 PPFIA2 CYP27B1 ITGB4 LPIN1 TNS4 CCDC158

9.78e-061961687a58bdf9de05d13d84211e09a933679d485bf8ab4
ToppCellcellseq-Epithelial-Epithelial_Airway|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

MUC16 ITGB4 PTPRZ1 EPHA2 TNS4 SLITRK6 MUC4

9.78e-061961687faa39c567f24403e511b240c1d1a654ffadd8473
DrugIsometheptene mucate; Up 200; 8.2uM; HL60; HT_HG-U133A

POU2F2 ZNF362 CDC14A GUCY2F PTPRZ1 DNAH17 AFDN PIMREG HCFC1 INPP5J MXD1 TBCD

2.83e-08200166123145_UP
Drugvalinomycin; Down 200; 0.1uM; PC3; HT_HG-U133A

EPHB3 MAPT POU2F2 SHROOM2 MTUS1 DNAH17 COBL HCFC1 NDRG4 MVK CPNE7

2.04e-07195166115911_DN
DrugFlecainide acetate [54143-56-5]; Down 200; 8.4uM; HL60; HT_HG-U133A

CYP27B1 ITGB4 GRPR CEP164 LAX1 TAOK2 NF1 MTUS1 DNAH17 TBCD

1.93e-06197166102557_DN
DrugCeftazidime pentahydrate [78439-06-2]; Down 200; 6.2uM; PC3; HT_HG-U133A

EPHB3 TCF7L2 TSPOAP1 MAPT LAX1 TAOK2 KANSL3 NF1 MVK CPNE7

2.11e-06199166105054_DN
Drugcellobiitol

MUC12 EPHA2 MUC3A MUC4 SOS1

7.00e-06371665CID000003871
DrugChicago sky blue 6B [2610-05-1]; Up 200; 4uM; MCF7; HT_HG-U133A

MAPT SLC13A2 TAOK2 NF1 MTUS1 DNAH17 HEY2 INPP5J CPNE7

1.37e-0519516693266_UP
DrugMifepristone [84371-65-3]; Down 200; 9.4uM; MCF7; HT_HG-U133A

TCF7L2 NR4A1 SLC9A1 ALMS1 WDR6 EPHA2 NDRG4 NOTCH1 MVK

1.43e-0519616697183_DN
DrugDosulepin hydrochloride [897-15-4]; Up 200; 12uM; MCF7; HT_HG-U133A

BORCS6 B3GNT4 GRPR CEP164 LPIN1 NF1 EPHA2 DMBT1 INPP5J

1.49e-0519716692864_UP
Drugtetraethylenepentamine pentahydrochloride; Up 200; 100uM; ssMCF7; HG-U133A

B3GNT4 MAPT USP24 POU2F2 NR4A1 CDC14A GLI1 PLXNA2 CPNE7

1.49e-051971669498_UP
DrugHydroxytacrine maleate (R,S) [118909-22-1]; Down 200; 12.2uM; MCF7; HT_HG-U133A

EPHB3 BORCS6 B3GNT4 COL7A1 TCF7L2 NF1 LRIG1 INPP5J RAD23B

1.55e-0519816693292_DN
DrugPyrvinium pamoate [3546-41-6]; Up 200; 3.4uM; HL60; HT_HG-U133A

PGS1 SIK1 SYNDIG1 NR4A1 CEP164 LAX1 MTUS1 AFDN

3.78e-0517116682957_UP
DrugMG-262; Down 200; 0.1uM; PC3; HT_HG-U133A

TCF7L2 DYNC2I1 SHROOM2 LCMT2 GRPR CES2 HOXA9 IL33

5.03e-0517816687079_DN
DrugLycorine hydrochloride [2188-68-3]; Down 200; 12.4uM; MCF7; HT_HG-U133A

B3GNT4 MAPT CUL9 GRPR CES2 ALMS1 HCFC1 INPP5J

6.86e-0518616686051_DN
Drugpioglitazone HCl; Up 200; 10uM; PC3; HT_HG-U133A

DMXL2 MAPT FRS3 POU2F2 ITGB4 LPIN1 MTUS1 DMBT1

6.86e-0518616685930_UP
Drug2-propylpentanoic acid; Up 200; 1000uM; MCF7; HT_HG-U133A_EA

EPHB3 ABCC4 MAPT CYP27B1 LPIN1 CCDC88A RUBCN NDRG4

7.12e-0518716681047_UP
Drugpioglitazone HCl; Down 200; 10uM; PC3; HT_HG-U133A

EPHB3 COL7A1 DELE1 GRPR FGD6 HCFC1 IL33 MVK

7.96e-0519016687528_DN
DrugPramoxine hydrochloride [637-58-1]; Up 200; 12.2uM; PC3; HT_HG-U133A

DMXL2 POU2F2 SYNDIG1 CDC14A KANSL3 NF1 AFDN RAD23B

8.88e-0519316683811_UP
DrugSTOCK1N-35215; Down 200; 10uM; PC3; HT_HG-U133A

EPHB3 DMXL2 POU2F2 ITGB4 CD33 TNS4 HCFC1 MVK

9.20e-0519416686380_DN
DrugDoxazosin mesylate [77883-43-3]; Up 200; 7.4uM; MCF7; HT_HG-U133A

B3GNT4 FRS3 NR4A1 GRPR PRKAA2 PLXNA2 INPP5J CPNE7

9.20e-0519416683363_UP
DrugBeta-Escin [11072-93-8]; Down 200; 3.2uM; PC3; HT_HG-U133A

FAT4 MAPT FRS3 ITGB4 NF1 HCFC1 IL33 TBCD

9.20e-0519416683807_DN
DrugIndomethacin [53-86-1]; Up 200; 11.2uM; HL60; HT_HG-U133A

BORCS6 FAT4 IRS1 CEP164 TAOK2 SLC9A1 NF1 MVK

9.20e-0519416682377_UP
DrugGraveoline [485-61-0]; Up 200; 14.4uM; PC3; HT_HG-U133A

COL7A1 DMXL2 POU2F2 CEP164 TAOK2 TNS4 PRKG1 SARDH

9.20e-0519416683716_UP
DrugFlumethasone [2135-17-3]; Up 200; 9.8uM; MCF7; HT_HG-U133A

BORCS6 B3GNT4 COL7A1 ZNF362 NR4A1 CDC14A EPS15L1 PLXNA2

9.54e-0519516684734_UP
DrugDipyrone [5907-38-0]; Down 200; 12uM; MCF7; HT_HG-U133A

B3GNT4 ITGB4 CDC14A TAOK2 NF1 HCFC1 MVK RAD23B

9.54e-0519516683835_DN
DrugPyrithyldione [77-04-3]; Down 200; 24uM; HL60; HT_HG-U133A

TCF7L2 CDC14A LPIN1 CCDC88A MTUS1 RUBCN TBCD SOS1

9.54e-0519516682740_DN
DrugHydroquinine hydrobromide hydrate [304695-81-6]; Up 200; 9.4uM; MCF7; HT_HG-U133A

DMXL2 SYNDIG1 NR4A1 CDC14A NF1 SARDH NDRG4 RAD23B

9.54e-0519516682767_UP
Drugalpha-estradiol; Down 200; 0.01uM; MCF7; HT_HG-U133A

EPHB3 ABCC4 TCF7L2 DELE1 NF1 EIF4ENIF1 NOTCH1 SOS1

9.88e-0519616686970_DN
DrugSulfanilamide [63-74-1]; Down 200; 23.2uM; PC3; HT_HG-U133A

B3GNT4 MAPT MUC5B SHROOM2 CDC14A CEP164 SLC9A1 NF1

1.02e-0419716684474_DN
DrugNifenazone [2139-47-1]; Up 200; 13uM; PC3; HT_HG-U133A

TCF7L2 FRS3 GRPR LAX1 CES2 NF1 TNS4 CPNE7

1.02e-0419716682122_UP
DrugRaloxifene hydrochloride [82640-04-8]; Down 200; 7.8uM; HL60; HT_HG-U133A

TCF7L2 CDC14A GRPR LPIN1 EPS15L1 NF1 MTUS1 TBCD

1.02e-0419716682738_DN
DrugStreptomycin sulfate [3810-74-0]; Down 200; 2.8uM; HL60; HG-U133A

PRPF31 NR4A1 NCOR1 EPS15L1 CCDC88A NF1 ALMS1 RUBCN

1.02e-0419716681578_DN
DrugRapamycin; Up 200; 0.1uM; HL60; HT_HG-U133A

COL4A1 TCF7L2 UBR4 CDC14A NF1 MTUS1 DNAH17 AFDN

1.02e-0419716682667_UP
DrugAC1L1GWI

FOXD3 GLI1 KCNK3

1.03e-04131663CID000054382
Drugestradiol, USP; Up 200; 0.01uM; HL60; HT_HG-U133A

TCF7L2 UBR4 SYNDIG1 CDC14A TAOK2 EPS15L1 MTUS1 TBCD

1.06e-0419816682701_UP
DrugCinnarizine [298-57-7]; Down 200; 10.8uM; MCF7; HT_HG-U133A

TCF7L2 DYNC2I1 TAOK2 NF1 MTUS1 COBL RPRD2 SOS1

1.06e-0419816687174_DN
DrugNadide [53-84-9]; Up 200; 6uM; MCF7; HT_HG-U133A

COL7A1 CUL9 ITGB4 CEP164 NF1 AFDN SIGLEC1 MUC6

1.06e-0419816687227_UP
DrugMetolazone [17560-51-9]; Up 200; 11uM; PC3; HT_HG-U133A

COL7A1 ITGB4 NCOR1 NF1 HCFC1 NDRG4 PLXNA2 CPNE7

1.06e-0419816686292_UP
DrugDiphenhydramine hydrochloride [147-24-0]; Down 200; 13.8uM; PC3; HT_HG-U133A

CYP27B1 CEP164 LPIN1 MTUS1 IL33 NDRG4 PLXNA2 MVK

1.10e-0419916687318_DN
DrugNomifensine maleate [32795-47-4]; Down 200; 11.2uM; MCF7; HT_HG-U133A

TCF7L2 USP24 SIK1 DELE1 SLC9A1 NF1 ALMS1 COBL

1.10e-0419916687217_DN
DrugMephenesin [59-47-2]; Up 200; 22uM; PC3; HT_HG-U133A

MAPT ACAD10 CEP164 LAX1 LPIN1 NF1 MTUS1 TBCD

1.10e-0419916687374_UP
Drug2-Chloropyrazine [14508-49-7]; Down 200; 35uM; PC3; HT_HG-U133A

MAPT CYP27B1 FRS3 CDC14A NCOR1 ALMS1 COBL NDRG4

1.14e-0420016685750_DN
Diseasecholangiocarcinoma (is_marker_for)

MUC16 MUC5B MUC3A MUC4 MUC6 NOTCH1

1.49e-06641636DOID:4947 (is_marker_for)
Diseaseobesity (implicated_via_orthology)

FAT4 SDK2 TCF7L2 MAPT IRS1 LPIN1 ALMS1 PRKAA2 NOTCH1

3.32e-062151639DOID:9970 (implicated_via_orthology)
Diseaselongevity, healthspan, parental longevity

TCF7L2 SLC6A4 KCNK3 FGD6

1.91e-05291634EFO_0004300, EFO_0007796, EFO_0009762
Diseaseglycodeoxycholate measurement

COL7A1 CSMD1 IL33

5.76e-05141633EFO_0010493
Diseaselymphocyte count

COL4A1 PALD1 TCF7L2 MBOAT1 PCDHGB1 MARK3 ACAD10 UBASH3A LAX1 SLC6A4 NCOR1 EPS15L1 ALMS1 SLC17A9 UMODL1 CD33 DNAH17 PRKAA2 SIGLEC1 DMBT1 MUC22

6.04e-05146416321EFO_0004587
Diseaserisk-taking behaviour

TCF7L2 INSYN1 MAPT MARK3 CUL9 GRM5 BIRC6 SLC6A4 TTBK1 NF1 PSORS1C1 LINC00208 CCDC171 PLXNA2

9.35e-0576416314EFO_0008579
Diseaseamino acid measurement

ZNF704 FAT4 ABCC4 MMP20 GRM5 SLC6A4 ALMS1 LRIG1 COBL PRKG1 CSMD1 PLXNA2 NOTCH1

1.07e-0467816313EFO_0005134
Diseaseinsulin measurement

ZNF704 TCF7L2 IRS1 GRM5 KANK1 LINC00208 COBL PRKG1

1.26e-042671638EFO_0004467
DiseaseMetastatic melanoma

SCYL1 SIK1 TTBK1 BRSK1

2.29e-04541634C0278883
Diseaseanxiety disorder (implicated_via_orthology)

SLC6A4 NCOR1 SCN1A

2.36e-04221633DOID:2030 (implicated_via_orthology)
Diseaseporokeratosis (is_implicated_in)

SLC17A9 MVK

3.00e-0451632DOID:3805 (is_implicated_in)
Diseasemucinous adenocarcinoma (is_marker_for)

MUC4 MUC6

3.00e-0451632DOID:3030 (is_marker_for)
DiseaseCerebral Small Vessel Diseases

COL4A1 SCN1A

3.00e-0451632C2733158
Diseaseneuroimaging measurement

TCF7L2 FBXL13 MAPT NBEAL1 MARK3 FAT3 TAOK2 SLC6A4 NCOR1 CCDC88A NF1 UTP4 HEY2 FGD6 PLXNA2 RAD23B

3.00e-04106916316EFO_0004346
Diseasecircadian rhythm

FBXL13 DAXX IL1RAPL1 LINC00208 RPRD2 CSMD1

3.01e-041631636EFO_0004354
Diseaseairway responsiveness measurement

ABCC4 USP24 CSMD1

3.08e-04241633EFO_0006897
DiseaseWest Syndrome

SIK1 PIGA TBCD

3.08e-04241633C0037769
DiseaseNoonan Syndrome

NF1 EPHA2 SOS1

3.08e-04241633C0028326
DiseaseCerebral Astrocytoma

NF1 HEY2 NOTCH1

3.48e-04251633C0750935
DiseaseIntracranial Astrocytoma

NF1 HEY2 NOTCH1

3.48e-04251633C0750936
DiseaseAstrocytoma

NF1 HEY2 NOTCH1

3.48e-04251633C0004114
DiseaseGrade I Astrocytoma

NF1 HEY2 NOTCH1

3.48e-04251633C1704230
DiseaseSubependymal Giant Cell Astrocytoma

NF1 HEY2 NOTCH1

3.48e-04251633C0205768
DiseaseMixed oligoastrocytoma

NF1 HEY2 NOTCH1

3.48e-04251633C0547065
DiseasePilocytic Astrocytoma

NF1 HEY2 NOTCH1

3.48e-04251633C0334583
DiseaseJuvenile Pilocytic Astrocytoma

NF1 HEY2 NOTCH1

3.48e-04251633C0280783
DiseaseDiffuse Astrocytoma

NF1 HEY2 NOTCH1

3.48e-04251633C0280785
DiseaseChildhood Cerebral Astrocytoma

NF1 HEY2 NOTCH1

3.48e-04251633C0338070
DiseaseGlioblastoma Multiforme

SIK1 NCOR1 NF1 GUCY2F NOTCH1

3.87e-041111635C1621958
DiseaseCerebrovascular accident

COL4A1 TBX3 PRKAA2 KCNK3

3.90e-04621634C0038454
DiseaseGemistocytic astrocytoma

NF1 HEY2 NOTCH1

3.92e-04261633C0334581
DiseaseProtoplasmic astrocytoma

NF1 HEY2 NOTCH1

3.92e-04261633C0334580
DiseaseFibrillary Astrocytoma

NF1 HEY2 NOTCH1

3.92e-04261633C0334582
Diseasebody fat percentage

PALD1 DMXL2 TCF7L2 SCYL1 IRS1 SLC6A4 LRIG1 KCNK3 SLITRK6 CCDC171

4.05e-0448816310EFO_0007800
Diseasecongestive heart failure (is_implicated_in)

EZH2 SLC6A4 SLC9A1

4.39e-04271633DOID:6000 (is_implicated_in)
DiseaseAnaplastic astrocytoma

NF1 HEY2 NOTCH1

4.39e-04271633C0334579
Diseasefish consumption measurement

ACAD10 GRM5 NF1 MVK

4.41e-04641634EFO_0010139
DiseaseEPILEPTIC ENCEPHALOPATHY, EARLY INFANTILE, 1

SIK1 SCN1A

4.48e-0461632C3463992
DiseasePorokeratosis, Disseminated Superficial Actinic

SLC17A9 MVK

4.48e-0461632C0265970
Diseasecortical thickness

PALD1 TCF7L2 FBXL13 MYCBP2 MAPT NBEAL1 MARK3 FAT3 CUL9 CCDC88A UMODL1 UTP4 KCNK3 CCDC171 PLXNA2 RAD23B

4.67e-04111316316EFO_0004840
Diseaseretinal detachment

FAT3 GRM5

6.25e-0471632EFO_0005773
Diseasepulse pressure measurement

COL4A1 TCF7L2 NBEAL1 MARK3 FAT3 DELE1 ACAD10 SLC13A2 CEP164 HOXA9 TTBK1 LRIG1 PSORS1C1 KCNK3 LINC00208 FGD6 HCFC1 NDRG4

7.16e-04139216318EFO_0005763
DiseaseSquamous cell carcinoma of lung

GUCY2F EPHA2 NOTCH1

7.30e-04321633C0149782
DiseaseX-linked infantile spasms

SIK1 SCN1A

8.31e-0481632C4552072
Diseasebitter alcoholic beverage consumption measurement

TCF7L2 DGLUCY NF1 CSMD1 PLXNA2

8.80e-041331635EFO_0010092
Diseasesleep duration

COL4A1 TCF7L2 MYCBP2 MAPT CUL9 MMP20 GRM5 SCN1A

9.50e-043621638EFO_0005271
Diseaseretinal detachment, retinal break

MAPT FAT3 GRM5

9.51e-04351633EFO_0005773, EFO_0010698
DiseaseGlioblastoma

DAXX NCOR1 NF1 NOTCH1

9.77e-04791634C0017636
Diseasehemangiopericytoma (is_marker_for)

HEY2 NOTCH1

1.06e-0391632DOID:264 (is_marker_for)
Diseaseamnestic disorder (implicated_via_orthology)

MAPT IRS1

1.06e-0391632DOID:10914 (implicated_via_orthology)
DiseaseCognition Disorders

ABCC4 MAPT SLC6A4

1.21e-03381633C0009241
Diseasestroke

COL4A1 NBEAL1 TTBK1 KCNK3 PRKG1

1.26e-031441635EFO_0000712
Diseasecortical surface area measurement

PALD1 TCF7L2 FBXL13 MYCBP2 MAPT NBEAL1 FAT3 CUL9 NCOR1 CCDC88A LRIG1 HEY2 PRKG1 FGD6 PLXNA2 SOS1 RAD23B

1.29e-03134516317EFO_0010736
Diseaseresponse to carboplatin, response to antineoplastic agent

LRIG1 CSMD1

1.33e-03101632GO_0097327, GO_0097328
Diseaseotitis media (is_marker_for)

MUC5B MUC4

1.33e-03101632DOID:10754 (is_marker_for)
DiseasePulmonary Hypertension

SLC6A4 KCNK3 PRKG1

1.41e-03401633C0020542
Diseasealcohol consumption measurement

TCF7L2 MAPT MARK3 POU2F2 GRID1 SYNDIG1 UBASH3A GRM5 BIRC6 SLC6A4 NF1 ALMS1 COBL RPRD2 CSMD1 PLXNA2

1.48e-03124216316EFO_0007878
DiseaseNeoplasm of uncertain or unknown behavior of breast

TBX3 NCOR1 NOTCH1

1.51e-03411633C0496956
DiseaseBreast adenocarcinoma

TBX3 NCOR1 NOTCH1

1.51e-03411633C0858252
Diseaseclinical treatment

TCF7L2 MYCBP2 MUC22

1.51e-03411633EFO_0007056
DiseaseNoonan Syndrome 1

EPHA2 SOS1

1.61e-03111632C4551602
DiseaseTurner Syndrome, Male

EPHA2 SOS1

1.61e-03111632C0041409
DiseaseFemale Pseudo-Turner Syndrome

EPHA2 SOS1

1.61e-03111632C1527404
Diseaseworry measurement

TCF7L2 MYCBP2 MAPT SLC6A4 MVK

1.69e-031541635EFO_0009589
Diseaseheart rate response to exercise

TCF7L2 LINC00208 MUC3A

1.74e-03431633EFO_0009184
DiseaseMemory Loss

MAPT GRPR SLC6A4

1.74e-03431633C0751295
DiseaseAge-Related Memory Disorders

MAPT GRPR SLC6A4

1.74e-03431633C0751292
DiseaseMemory Disorder, Spatial

MAPT GRPR SLC6A4

1.74e-03431633C0751294
DiseaseMemory Disorder, Semantic

MAPT GRPR SLC6A4

1.74e-03431633C0751293
DiseaseMemory Disorders

MAPT GRPR SLC6A4

1.74e-03431633C0025261
Diseaseparental longevity

COL4A1 ZNF704 GRM5 SLC6A4 PSORS1C1 KCNK3 CSMD1 MUC22 CCDC171

1.77e-034941639EFO_0007796
DiseaseMemory impairment

MAPT GRPR SLC6A4

1.86e-03441633C0233794
DiseaseGastric Adenocarcinoma

EPHA2 PRKAA2 BRSK1

1.98e-03451633C0278701
DiseaseParkinson disease

MYCBP2 MAPT LRRK2 MUC12 ITGAE HEATR6 DNAH17

2.12e-033211637MONDO_0005180
Diseaseage-related hearing impairment

FBXL13 ACADVL SIK1 DGLUCY EIF4ENIF1 PRKG1 CSMD1

2.23e-033241637EFO_0005782
Diseasesquamous cell carcinoma, multiple keratinocyte carcinoma susceptibility measurement, basal cell carcinoma

PALD1 CSMD1

2.27e-03131632EFO_0000707, EFO_0004193, EFO_0007932
DiseaseRespiratory Depression

MAPT TBCD

2.27e-03131632C0235063
DiseaseRespiratory Insufficiency

MAPT TBCD

2.27e-03131632C0035229
DiseaseRespiratory Failure

MAPT TBCD

2.27e-03131632C1145670
Diseasehealthspan

TCF7L2 UBASH3A

2.27e-03131632EFO_0009762
DiseaseProstatic Neoplasms

TBX3 ABCC4 IRS1 EZH2 GRPR NCOR1 NCOA7 RPRD2 MUC4 RAD23B

2.33e-0361616310C0033578
DiseaseMalignant neoplasm of prostate

TBX3 ABCC4 IRS1 EZH2 GRPR NCOR1 NCOA7 RPRD2 MUC4 RAD23B

2.33e-0361616310C0376358
DiseaseCardiomyopathy, Dilated

TCF7L2 SIK1 ALMS1

2.39e-03481633C0007193
Diseasemelanoma

FAT4 UBR4 PCDHB8 IL1RAPL1 HOXA9 NF1

2.63e-032481636C0025202
DiseaseCardiomyopathy, Familial Idiopathic

TCF7L2 SIK1 ALMS1

2.68e-03501633C1449563
Diseasequinate measurement

LRRK2 GRID1

3.04e-03151632EFO_0021167
DiseaseRASopathy

NF1 SOS1

3.04e-03151632cv:C5555857
DiseaseFamilial thoracic aortic aneurysm and aortic dissection

COL4A1 PRKG1 NOTCH1

3.17e-03531633C4707243
Diseaseplasminogen activator inhibitor 1 measurement

UBR4 MUC12 MUC17

3.34e-03541633EFO_0004792
DiseaseAcute Cerebrovascular Accidents

TBX3 PRKAA2 KCNK3

3.34e-03541633C0751956
DiseaseNeuralgia, Supraorbital

GRM5 PRKG1

3.46e-03161632C0038870
DiseaseNeuralgia

GRM5 PRKG1

3.46e-03161632C0027796
Diseaseureidopropionic acid measurement

ZNF704 OTOG

3.46e-03161632EFO_0010542
Diseaseendoplasmic reticulum resident protein 29 measurement

PSORS1C1 MUC22

3.46e-03161632EFO_0020346
DiseaseNeuralgia, Atypical

GRM5 PRKG1

3.46e-03161632C0234247
DiseaseNeuralgia, Stump

GRM5 PRKG1

3.46e-03161632C0234249
Diseaseresponse to thioamide, Drug-induced agranulocytosis

PSORS1C1 MUC22

3.46e-03161632EFO_0007633, HP_0012235
DiseaseNeuralgia, Iliohypogastric Nerve

GRM5 PRKG1

3.46e-03161632C0423712
DiseaseNeuralgia, Perineal

GRM5 PRKG1

3.46e-03161632C0423711
Diseasecentral nervous system disease (implicated_via_orthology)

SEC31A TAOK2

3.46e-03161632DOID:331 (implicated_via_orthology)

Protein segments in the cluster

PeptideGeneStartEntry
LHSAPGNASTTVSRL

UMODL1

216

Q5DID0
HSGTALPTSKSTTRL

AFDN

541

P55196
VSPGSLTFHSLSLRS

LINC00208

61

Q96KT6
SSSSLLASPGHISVK

ESYT2

736

A0FGR8
LRSTPSHGSVSSLNS

EPS15L1

236

Q9UBC2
ALVHTSPSTAGSALL

EPC1

706

Q9H2F5
AINTLHSSRTLPGAS

CELF3

151

Q5SZQ8
HSSRTLPGASSSLVV

CELF3

156

Q5SZQ8
SPISSNSHRSLDGLS

BIRC6

581

Q9NR09
GTDLPAALLSTTHET

CSMD1

2046

Q96PZ7
HTTILRPSYTGLSSS

CDC14A

561

Q9UNH5
TGSTLSSVSPRLGSH

PRKAA2

521

P54646
SIGSRDHSNLSIPSR

CCDC171

1251

Q6TFL3
RHLSSTTPVFLAGVL

H2AL3

41

A0A3B3IU63
ATIPESHSIGSIVRT

FAT4

3096

Q6V0I7
TGTATVLSTPHSHRE

ALMS1

706

Q8TCU4
HTSRGGLVISPESLS

ACAD10

646

Q6JQN1
ISHRGITSAFPTTAS

AMER1

676

Q5JTC6
TAPTSLSGQHRSLRL

C8orf58

126

Q8NAV2
IRATPSAGHLSSSSI

DMXL2

991

Q8TDJ6
DSSTRVDSPSHGLVT

DAXX

681

Q9UER7
VDSPSHGLVTSSLCI

DAXX

686

Q9UER7
TPSTLKAGELRTHVS

COL4A1

1646

P02462
GHTRATSRTTATATP

MUC5B

2831

Q9HC84
GHTRGTSRTTATATP

MUC5B

3531

Q9HC84
SIPGTTHTARVLTTT

MUC5B

4641

Q9HC84
ITPHRTSFGGILSSA

NBEAL1

736

Q6ZS30
TTTTSSGGHPLEFLR

RAD23B

266

P54727
HISVQALTSRGSSDP

TSPOAP1

856

O95153
TSRHSGSTLAPEQTR

INSYN1

246

Q2T9L4
GTLILLHRSGTTSQP

PALD1

326

Q9ULE6
TSLVRAHLDSGPSTA

NR4A1

366

P22736
TALHSEITAALSPGS

CYP27B1

341

O15528
VSVGALLPDATSSHR

HCFC1

1371

P51610
LLPDATSSHRTVESG

HCFC1

1376

P51610
GLHASESTPCRLSTT

HEY2

201

Q9UBP5
SSHPTRELRTTGSTS

MUC16

476

Q8WXI7
RLDTSHLPIGTTASS

MUC16

1051

Q8WXI7
LTLATTTAPLARTHS

MUC16

9971

Q8WXI7
TSHGEGVSPTTILRT

MUC16

11956

Q8WXI7
ELLSASASHGAIPVS

MUC4

846

Q99102
SASTGHASPLLVTDA

MUC4

1736

Q99102
GHATPLLVTDASSIS

MUC4

2076

Q99102
SASTGHAIPLLVTDT

MUC4

2216

Q99102
GHATPLLVTDASSAS

MUC4

2636

Q99102
GHATPLLVTDASSAS

MUC4

3196

Q99102
GHATPLLVTDASSVS

MUC4

3756

Q99102
VSTGHATSLPVTSRS

MUC4

3961

Q99102
VTSRSSASTGHATPL

MUC4

3971

Q99102
TRFLTSSLTAHGSTP

MUC6

2316

Q6W4X9
SSVSTQRALPGSRHL

FOXI3

326

A8MTJ6
GHLVSSDLSPRVTAV

MDN1

256

Q9NU22
ALHTETRSTVVGSPT

MDN1

2346

Q9NU22
PRLSHLPVASGTSTV

NOTCH1

2271

P46531
PISTLSHRAGSASRT

GRM5

1021

P41594
GPESSRHTTLSLLTK

MXD1

86

Q05195
AVPSLGAASSHVVSL

LRIG1

106

Q96JA1
AHGVRTTTGSTREPT

MUC22

1611

E2RYF6
RTGSTPSIASTHSEL

MTUS1

796

Q9ULD2
APRSAISSVSTGLHS

KCNK3

366

O14649
STHIGPRTTRAQGIS

PRKG1

51

Q13976
SLGPRTTHSSVLIIT

CD33

186

P20138
STDGILTSVNHRSPL

DYNC2I1

751

Q8WVS4
GTESSSHSRLSPRKT

DKKL1

216

Q9UK85
TGSRVHASRPASLDS

CCDC88A

1576

Q3V6T2
HASRPASLDSGRTST

CCDC88A

1581

Q3V6T2
LVRRPHSLSSELTGT

ITGAE

111

P38570
QPVHILTSVSSLRGT

EZH2

66

Q15910
PSSISVSEHSRLLSL

PLXNA2

566

O75051
TSTALATAHPDLRST

IL1RAPL1

596

Q9NZN1
PALSSRTSITLHISD

PCDHGB1

426

Q9Y5G3
RGTTSTLHTTVESTP

MUC3A

931

Q02505
GVSSSHVRVLSSPAE

PGS1

91

Q32NB8
SPIRTTHTGQVLGSL

CES2

31

O00748
RGDCPTLDTHTLSLT

HOXA9

141

P31269
SSLTLLGAIVSTHAP

HEATR6

581

Q6AI08
TTLSSAVGTLHPSRT

POU2F2

401

P09086
GSSIRHSPLSSGIST

KANK1

236

Q14678
IRGRTLESSTLHVTP

LAX1

11

Q8IWV1
GTITRSDTLGHILPT

LPIN1

681

Q14693
RASSSPVILVGTHLD

LRRK2

1441

Q5S007
VPTLRLHSSSGSSLT

EPHB3

456

P54753
SLSHTGTTVSRRVGP

GLI1

521

P08151
ITAVSPHRDGSVTST

PTPRZ1

1376

P23471
SPTHSLSQKSTRLSG

PIMREG

131

Q9BSJ6
AATTTLAPGLSTHED

CYHR1

46

Q6ZMK1
FRKRTHSAGTSPTIT

IRS1

521

P35568
VSSHDSRLTAGVPDT

ITGB4

1516

P16144
PALHIGSISATDRDS

PCDHB12

466

Q9Y5F1
VSEALRSAGLPSHSS

MRPS36

36

P82909
TGSPSGSSVVRLVDH

PPP4R3C

786

Q6ZMV5
TRSPVFSHLSSSLQG

ABCC4

896

O15439
SLLSTLCRGSPVVTH

HECTD1

281

Q9ULT8
RALHDSSITGISPIT

IL33

106

O95760
TISSPLELEGTVSRH

BORCS6

196

Q96GS4
TVSSASLSLPSRHRL

B3GNT4

81

Q9C0J1
SHLRTATPATVSRAG

DNAH17

2246

Q9UFH2
GSASTHRRPSATLIA

SLC25A18

156

Q9H1K4
VLATITPESSLDSGH

FRMPD3

791

Q5JV73
TSSLRHPSLGEESTH

FRS3

166

O43559
GLTRTSVTVSDLEPH

EPHA2

391

P29317
TESSHLARTGPSFLL

CPNE7

151

Q9UBL6
SSGTAQRSLLSPLHR

DUSP16

491

Q9BY84
TGLPYRIHVSLSTVT

GUCY2F

1016

P51841
QPGLIIRSHSTGRST

GRPR

341

P30550
SPHATGIRIISLSSS

COBL

741

O75128
TGPADSVSLSLHNSR

FAT3

4496

Q8TDW7
SRITSLVFTGAPHIS

FBXL13

376

Q8NEE6
IPSLSHSVLSQTSFR

BRSK1

631

Q8TDC3
HPGALLDSQSTRTIT

MARF1

131

Q9Y4F3
PGTTSSDVRHAVATI

MBOAT1

56

Q6ZNC8
LSHEATPLSQTRSRG

MARK3

586

P27448
LPEQSSHGTSRTLSS

GRID1

931

Q9ULK0
HTLQSRLVATSPGSS

KANSL3

726

Q9P2N6
SNSGSLRTSRHIPLT

KRTAP26-1

11

Q6PEX3
AESGTPSLTAAVLHT

CUL9

131

Q8IWT3
LGPVRTVHVTQASSS

COL7A1

686

Q02388
SSETLSREPVTLHAG

CCDC158

971

Q5M9N0
SLSHARSVLITTGFP

DGLUCY

326

Q7Z3D6
HASTAGPESSLALRL

DMBT1

351

Q9UGM3
IRSHSDTSIASRGAP

RUBCN

406

Q92622
GLSRVRESLTLPSHS

RPRD2

1361

Q5VT52
ALPVTSASSEGRAHL

SLC13A2

196

Q13183
ESGSLLISPTHISDA

SDK2

456

Q58EX2
TLLAGTSRLPHASST

DELE1

461

Q14154
THQPLSLSRTTATIA

FOXD3

431

Q9UJU5
ARVHPGTSITASVTA

PPFIA2

696

O75334
TITVTDLGTPRLTTH

PCDHB8

421

Q9UN66
ISRSPTSSGSHKAVL

OTOG

1666

Q6ZRI0
HLRTGIRPSTITSSF

MMP20

326

O60882
SRHLSIGSLNSATPE

NOXRED1

61

Q6NXP6
VRHTPVASSEASTLS

MUC17

1226

Q685J3
RTVAHSPTALISGGT

UTP4

291

Q969X6
RHSPATISSSTRGLG

TBX3

436

O15119
ISLHSQTPVLSSRGS

SLITRK6

16

Q9H5Y7
HRVGASTVPASLDSS

SYNDIG1

51

Q9H7V2
GVSSLTSKLIRSHPT

SCYL1

576

Q96KG9
SSRETSHGSPTVTKL

NCOA7

376

Q8NI08
SRHTSVVSSGPSVLR

NCOR1

1446

O75376
VVSSGPSVLRSTLHE

NCOR1

1451

O75376
QESLPSSTGRRHTLA

SIK1B

461

A0A0B4J2F2
QESLPSSTGRRHTLA

SIK1

461

P57059
GSVDSLDHPSSRLSV

SHROOM2

176

Q13796
VARLSLSHSPSVFSS

SHROOM2

1106

Q13796
GSITAVTPLLAHLSS

SLC17A9

101

Q9BYT1
RAGTLTSLESSHSVP

TAOK2

341

Q9UL54
LALPTGSRALTTRSH

MYCBP2

1176

O75592
GLTSTLPDTVLSHLF

NDRG4

156

Q9ULP0
SAHDVTLSPVLSALG

PXYLP1

376

Q8TE99
GAAVSLSTPHLLAAS

RUSC1-AS1

91

Q66K80
LPHGPRSASVSSISL

SOS1

1126

Q07889
GTESDLTVSRLAPSH

SARDH

616

Q9UL12
SPHQSLLSIRGSLFS

SCN1A

551

P35498
VLSRASRSLSEGHPT

ACADVL

581

P49748
HVTAAVSSRRSGSPL

EIF4ENIF1

126

Q9NRA8
SSSLGSTPHEELERL

EIF4ENIF1

351

Q9NRA8
DSTPSLTSRKIHGLS

CEP164

1251

Q9UPV0
HRASATLSRVSPGSL

PIGA

11

P37287
HRSSSLAPTSVGQLV

INPP5J

101

Q15735
TVADLLHSSGPSLRS

TEX44

316

Q53QW1
RSHGAAPALDTAITS

TTBK1

1176

Q5TCY1
PETGHTISLSCLSAL

VSIG1

151

Q86XK7
ITPSTHSSVSSGLLR

RNF148

6

Q8N7C7
FLRVLGGTSPTLSHS

TMEM94

386

Q12767
SLHSLGSVSLCTRPS

TNS4

316

Q8IZW8
SIGAPGVSIHSATSL

MVK

371

Q03426
NGSSRTLHSRTETTP

RELL1

31

Q8IUW5
LSPTARTLHFQSGST

TCF7L2

121

Q9NQB0
SSALSSVLHSIPSGR

FGD6

1301

Q6ZV73
SGIHLSASRTLAPTL

PSORS1C1

121

Q9UIG5
RKTLSGFSSTSVLPH

PRPF31

256

Q8WWY3
VATGPLSLRASTHGL

NF1

2111

P21359
VLRSHGLQLSPTAST

SLC9A1

31

P19634
AVSSGHSTLPPLVSR

TRABD2A

391

Q86V40
SPRHLSNVSSTGSID

MAPT

721

P10636
GSATTSLAAPISLHV

SIGLEC1

966

Q9BZZ2
SSAHPSLVVSSSGRR

TRIM72

296

Q6ZMU5
TTRSRESSPSHGLLK

VCPIP1

991

Q96JH7
ALPTTTGSAHALTAV

WDR6

756

Q9NNW5
AHTVLSSPPRGTVSL

ZNF704

361

Q6ZNC4
IDVASVSSTLAGHLP

ZXDA

631

P98168
SSALGGPTLTHAVTR

USP24

881

Q9UPU5
LHARPATSTVTGLGL

ZNF362

106

Q5T0B9
TGLRAVTHTSPEDVS

TBCD

796

Q9BTW9
ASRGDTLSHTLVFPS

LCMT2

311

O60294
TLSPTITSGLHNIAR

SEC31A

1161

O94979
GDDTRHSIPATTTTL

SLC6A4

56

P31645
ISESLVRHASTSSPA

UBR4

1751

Q5T4S7
TAHLATTRNTSPSLG

TREX1

251

Q9NSU2
VSHGSTLDSCTRPLL

UBASH3A

586

P57075
LETGHRCSSSSSLPV

USP54

1446

Q70EL1
TTFHSRPGSTETTLL

MUC12

721

Q9UKN1
IPTTHISARSTTSGL

MUC12

811

Q9UKN1
GLSERSTTFHSSPRS

MUC12

961

Q9UKN1
VEASTRVHSSTGSPR

MUC12

2186

Q9UKN1
EASTRVHSSTGSPRT

MUC12

2661

Q9UKN1
LGRSEESTTVHSSPV

MUC12

4711

Q9UKN1