Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionbenzodiazepine receptor binding

TSPOAP1 RIMBP3 RIMBP3C RIMBP3B

8.80e-0951314GO:0030156
GeneOntologyMolecularFunctionguanyl-nucleotide exchange factor activity

TRIO KALRN PLEKHG4 DOCK11 ITSN1 ARFGEF2 ARFGEF1 IQSEC1 FGD1 PREX1

3.00e-0623113110GO:0005085
GeneOntologyMolecularFunctionnucleoside-triphosphatase regulator activity

TRIO KALRN PLEKHG4 DOCK11 ITSN1 GPS1 ARFGEF2 ARFGEF1 IQSEC1 FGD1 PREX1 ACAP3

1.30e-0450713112GO:0060589
GeneOntologyMolecularFunctionGTPase regulator activity

TRIO KALRN PLEKHG4 DOCK11 ITSN1 GPS1 ARFGEF2 ARFGEF1 IQSEC1 FGD1 PREX1 ACAP3

1.30e-0450713112GO:0030695
GeneOntologyMolecularFunction5'-3' exonuclease activity

DCP2 FAN1 XRN1

2.10e-04181313GO:0008409
GeneOntologyMolecularFunctionvoltage-gated calcium channel activity

TRPV1 TSPOAP1 RYR1 CACNA1I

2.33e-04461314GO:0005245
GeneOntologyMolecularFunction5'-3' RNA exonuclease activity

DCP2 XRN1

2.54e-0441312GO:0004534
GeneOntologyMolecularFunction2'-5'-oligoadenylate synthetase activity

OAS1 OAS3

4.22e-0451312GO:0001730
GeneOntologyMolecularFunctionphosphoric diester hydrolase activity

PDE4A FAN1 PDE8B GNAS PLCH1

4.48e-04971315GO:0008081
GeneOntologyMolecularFunctiondynein complex binding

TPR CENPF CNTRL

8.02e-04281313GO:0070840
GeneOntologyBiologicalProcessmulticellular organismal reproductive process

UBR2 PRAMEF7 KIF18A KALRN TOPAZ1 CNTRL OAS1 PRAMEF8 RIMBP3 BNC1 FSIP2 NLRP14 SERPINE2 IGF1R BRCA2 HPGD PLEKHA1 RIMBP3C GNAS RIMBP3B DEDD KNL1

4.64e-06119412922GO:0048609
GeneOntologyBiologicalProcessnegative regulation of chromosome organization

TPR CENPF DCP2 CEP192 XRN1 SLX4 KNL1

4.93e-061071297GO:2001251
GeneOntologyBiologicalProcessgamete generation

UBR2 PRAMEF7 KIF18A TOPAZ1 CNTRL OAS1 PRAMEF8 RIMBP3 BNC1 FSIP2 NLRP14 BRCA2 HPGD PLEKHA1 RIMBP3C GNAS RIMBP3B DEDD KNL1

1.14e-0598212919GO:0007276
GeneOntologyBiologicalProcesssexual reproduction

UBR2 PRAMEF7 KIF18A TOPAZ1 CNTRL OAS1 PRAMEF8 RIMBP3 BNC1 FSIP2 NLRP14 IGF1R BRCA2 HPGD XRN1 PLEKHA1 RIMBP3C GNAS RIMBP3B DEDD SLX4 KNL1

2.04e-05131212922GO:0019953
GeneOntologyBiologicalProcessregulation of small GTPase mediated signal transduction

TRIO KALRN PLEKHG4 ITSN1 ARFGEF2 ARFGEF1 IQSEC1 FGD1 PREX1 NOTCH2

4.73e-0533312910GO:0051056
GeneOntologyBiologicalProcessadenylate cyclase-activating dopamine receptor signaling pathway

ADCY5 GNAL GNAS

6.53e-05131293GO:0007191
GeneOntologyBiologicalProcessneuromuscular synaptic transmission

TSPOAP1 RIMBP3 RIMBP3C RIMBP3B

7.37e-05361294GO:0007274
GeneOntologyBiologicalProcessdevelopmental process involved in reproduction

UBR2 PRAMEF7 KIF18A TOPAZ1 CNTRL OAS1 PRAMEF8 RIMBP3 BNC1 FSIP2 NLRP14 SERPINE2 IGF1R BRCA2 PLEKHA1 RIMBP3C GNAS RIMBP3B DEDD KNL1

8.23e-05123512920GO:0003006
GeneOntologyBiologicalProcesshomologous chromosome orientation in meiotic metaphase I

BRCA2 KNL1

1.16e-0431292GO:0031619
GeneOntologyBiologicalProcesspostsynaptic modulation of chemical synaptic transmission

TRIO SLC1A1 IGF1R IQSEC1

1.36e-04421294GO:0099170
GeneOntologyBiologicalProcesssmall GTPase-mediated signal transduction

TRIO KALRN PLEKHG4 DOCK11 ITSN1 PECAM1 ARFGEF2 ARFGEF1 IQSEC1 FGD1 PREX1 NOTCH2

1.44e-0453812912GO:0007264
GeneOntologyBiologicalProcessG protein-coupled dopamine receptor signaling pathway

SLC1A1 ADCY5 GNAL GNAS

1.63e-04441294GO:0007212
GeneOntologyBiologicalProcesspositive regulation of chemokine production

OAS1 OAS3 CSF1R LRP1 C5

1.84e-04841295GO:0032722
GeneOntologyBiologicalProcessgerm cell development

PRAMEF7 CNTRL PRAMEF8 RIMBP3 BNC1 FSIP2 BRCA2 RIMBP3C GNAS RIMBP3B KNL1

2.26e-0448212911GO:0007281
GeneOntologyBiologicalProcessnegative regulation of IP-10 production

OAS1 OAS3

2.31e-0441292GO:0071659
GeneOntologyBiologicalProcessubiquitin-dependent protein catabolic process via the N-end rule pathway

UBR2 UBR4

2.31e-0441292GO:0071596
GeneOntologyBiologicalProcessanterograde trans-synaptic signaling

TRPV1 PDE4A TRIO TSPOAP1 SLC1A1 INSYN2A RIMBP3 SERPINE2 IGF1R IQSEC1 RIMBP3C C22orf39 GNAL FBXL20 CADPS2 RIMBP3B

2.33e-0493112916GO:0098916
GeneOntologyBiologicalProcesschemical synaptic transmission

TRPV1 PDE4A TRIO TSPOAP1 SLC1A1 INSYN2A RIMBP3 SERPINE2 IGF1R IQSEC1 RIMBP3C C22orf39 GNAL FBXL20 CADPS2 RIMBP3B

2.33e-0493112916GO:0007268
GeneOntologyBiologicalProcesstrans-synaptic signaling

TRPV1 PDE4A TRIO TSPOAP1 SLC1A1 INSYN2A RIMBP3 SERPINE2 IGF1R IQSEC1 RIMBP3C C22orf39 GNAL FBXL20 CADPS2 RIMBP3B

2.57e-0493912916GO:0099537
GeneOntologyBiologicalProcessmitotic spindle assembly checkpoint signaling

TPR CENPF CEP192 KNL1

2.91e-04511294GO:0007094
GeneOntologyBiologicalProcessspindle assembly checkpoint signaling

TPR CENPF CEP192 KNL1

2.91e-04511294GO:0071173
GeneOntologyBiologicalProcessnegative regulation of organelle organization

TPR CENPF PECAM1 DCP2 ARFGEF1 CEP192 SPTBN5 XRN1 SLX4 KNL1

3.20e-0442112910GO:0010639
GeneOntologyBiologicalProcessnegative regulation of mitotic metaphase/anaphase transition

TPR CENPF CEP192 KNL1

3.37e-04531294GO:0045841
GeneOntologyBiologicalProcessnegative regulation of mitotic sister chromatid segregation

TPR CENPF CEP192 KNL1

3.37e-04531294GO:0033048
GeneOntologyBiologicalProcessnegative regulation of sister chromatid segregation

TPR CENPF CEP192 KNL1

3.37e-04531294GO:0033046
GeneOntologyBiologicalProcessnegative regulation of mitotic sister chromatid separation

TPR CENPF CEP192 KNL1

3.37e-04531294GO:2000816
GeneOntologyBiologicalProcessmitotic spindle checkpoint signaling

TPR CENPF CEP192 KNL1

3.37e-04531294GO:0071174
GeneOntologyBiologicalProcesssecretion by cell

TRPV1 KALRN TSPOAP1 STXBP4 ITSN1 ARFGEF2 ARFGEF1 ADCY5 SERPINE2 PDE8B EXOC6B LRP1 CACNA1I GNAS FBXL20 CADPS2 TPH1

3.45e-04106412917GO:0032940
GeneOntologyBiologicalProcessregulation of IP-10 production

OAS1 OAS3

3.83e-0451292GO:0071658
GeneOntologyBiologicalProcessIP-10 production

OAS1 OAS3

3.83e-0451292GO:0071612
GeneOntologyBiologicalProcessmeiotic metaphase I homologous chromosome alignment

BRCA2 KNL1

3.83e-0451292GO:0043060
GeneOntologyBiologicalProcessregulation of ARF protein signal transduction

ARFGEF2 ARFGEF1 IQSEC1

3.86e-04231293GO:0032012
GeneOntologyBiologicalProcessnegative regulation of metaphase/anaphase transition of cell cycle

TPR CENPF CEP192 KNL1

3.89e-04551294GO:1902100
GeneOntologyBiologicalProcessnegative regulation of chromosome separation

TPR CENPF CEP192 KNL1

3.89e-04551294GO:1905819
GeneOntologyBiologicalProcesssynaptic signaling

TRPV1 PDE4A TRIO TSPOAP1 SLC1A1 INSYN2A RIMBP3 SERPINE2 IGF1R IQSEC1 RIMBP3C C22orf39 GNAL FBXL20 CADPS2 RIMBP3B

3.94e-0497612916GO:0099536
GeneOntologyBiologicalProcesschemokine (C-X-C motif) ligand 2 production

OAS1 OAS3 LRP1

4.39e-04241293GO:0072567
GeneOntologyBiologicalProcessARF protein signal transduction

ARFGEF2 ARFGEF1 IQSEC1

4.39e-04241293GO:0032011
GeneOntologyBiologicalProcessregulation of chemokine (C-X-C motif) ligand 2 production

OAS1 OAS3 LRP1

4.39e-04241293GO:2000341
GeneOntologyBiologicalProcessspindle checkpoint signaling

TPR CENPF CEP192 KNL1

4.46e-04571294GO:0031577
GeneOntologyBiologicalProcessnegative regulation of chromosome segregation

TPR CENPF CEP192 KNL1

4.46e-04571294GO:0051985
GeneOntologyBiologicalProcesscellular process involved in reproduction in multicellular organism

PRAMEF7 CNTRL PRAMEF8 RIMBP3 BNC1 FSIP2 BRCA2 RIMBP3C GNAS RIMBP3B KNL1

4.81e-0452712911GO:0022412
GeneOntologyBiologicalProcesscAMP metabolic process

PDE4A ADCY5 PDE8B

4.97e-04251293GO:0046058
GeneOntologyBiologicalProcessfemale gamete generation

PRAMEF7 CNTRL OAS1 PRAMEF8 BNC1 BRCA2 HPGD

5.15e-042231297GO:0007292
GeneOntologyBiologicalProcessregulation of mitotic sister chromatid segregation

TPR CENPF CEP192 KNL1

5.43e-04601294GO:0033047
GeneOntologyBiologicalProcessmeiotic metaphase chromosome alignment

BRCA2 KNL1

5.73e-0461292GO:0051311
GeneOntologyBiologicalProcessnegative regulation of chemokine (C-X-C motif) ligand 2 production

OAS1 OAS3

5.73e-0461292GO:2000342
GeneOntologyBiologicalProcessnegative regulation of mitotic nuclear division

TPR CENPF CEP192 KNL1

6.94e-04641294GO:0045839
GeneOntologyBiologicalProcesscellular response to dopamine

SLC1A1 ADCY5 GNAL GNAS

6.94e-04641294GO:1903351
GeneOntologyBiologicalProcessregulation of mitotic sister chromatid separation

TPR CENPF CEP192 KNL1

6.94e-04641294GO:0010965
GeneOntologyBiologicalProcessresponse to dopamine

SLC1A1 ADCY5 GNAL GNAS

7.80e-04661294GO:1903350
GeneOntologyBiologicalProcesspositive regulation of pigment cell differentiation

BLOC1S5 ADAMTS20

7.99e-0471292GO:0050942
GeneOntologyBiologicalProcessmitotic sister chromatid separation

TPR CENPF CEP192 KNL1

8.25e-04671294GO:0051306
GeneOntologyBiologicalProcessexport from cell

TRPV1 KALRN TSPOAP1 STXBP4 ITSN1 ARFGEF2 ARFGEF1 ADCY5 SERPINE2 PDE8B EXOC6B LRP1 CACNA1I GNAS FBXL20 CADPS2 TPH1

8.54e-04115312917GO:0140352
GeneOntologyBiologicalProcesscellular response to monoamine stimulus

SLC1A1 ADCY5 GNAL GNAS

8.73e-04681294GO:0071868
GeneOntologyBiologicalProcesscellular response to catecholamine stimulus

SLC1A1 ADCY5 GNAL GNAS

8.73e-04681294GO:0071870
GeneOntologyBiologicalProcessmale gamete generation

UBR2 KIF18A TOPAZ1 RIMBP3 BNC1 FSIP2 NLRP14 BRCA2 PLEKHA1 RIMBP3C RIMBP3B DEDD KNL1

9.88e-0476212913GO:0048232
GeneOntologyCellularComponentmicrotubule organizing center

KIF18A CENPF DZIP1L CNTRL UBR4 ARFGEF2 CEP192 RILP SKI RASSF7 KIAA0753 DHX9 BRCA2 TTLL6 CEP112 PDE4DIP LRP1 DDHD2

1.94e-0591913218GO:0005815
GeneOntologyCellularComponentruffle

KIF18A PDE4A MYO10 PECAM1 FGD1 PLEKHA1 GNAS

3.40e-042061327GO:0001726
GeneOntologyCellularComponentcentrosome

KIF18A CENPF CNTRL UBR4 ARFGEF2 CEP192 SKI RASSF7 KIAA0753 DHX9 BRCA2 CEP112 PDE4DIP DDHD2

3.71e-0477013214GO:0005813
GeneOntologyCellularComponentSchaffer collateral - CA1 synapse

PDE4A TRIO STXBP4 SLC1A1 IQSEC1 FBXL20

4.58e-041551326GO:0098685
GeneOntologyCellularComponentextrinsic component of membrane

PDE4A TRIO KALRN PLEKHG4 RYR1 GNAL GNAS

6.56e-042301327GO:0019898
GeneOntologyCellularComponentmanchette

RIMBP3 RIMBP3C RIMBP3B

7.18e-04281323GO:0002177
DomainPH

TRIO KALRN PLEKHG4 DOCK11 MYO10 ITSN1 SPTBN5 OSBPL1A IQSEC1 FGD1 PLEKHA1 PLCH1 CADPS2 PREX1 ACAP3

7.03e-1027812715SM00233
DomainPH_DOMAIN

TRIO KALRN PLEKHG4 DOCK11 MYO10 ITSN1 SPTBN5 OSBPL1A IQSEC1 FGD1 PLEKHA1 PLCH1 CADPS2 PREX1 ACAP3

7.38e-1027912715PS50003
DomainPH_domain

TRIO KALRN PLEKHG4 DOCK11 MYO10 ITSN1 SPTBN5 OSBPL1A IQSEC1 FGD1 PLEKHA1 PLCH1 CADPS2 PREX1 ACAP3

7.76e-1028012715IPR001849
DomainPH

TRIO KALRN PLEKHG4 DOCK11 MYO10 ITSN1 SPTBN5 FGD1 PLEKHA1 CADPS2 PREX1 ACAP3

5.38e-0822912712PF00169
Domain-

TRIO KALRN PLEKHG4 DOCK11 MYO10 ITSN1 SPTBN5 OSBPL1A IQSEC1 FGD1 PLEKHA1 PLCH1 CADPS2 PREX1 ACAP3

6.89e-08391127152.30.29.30
DomainPH_dom-like

TRIO KALRN PLEKHG4 DOCK11 MYO10 ITSN1 SPTBN5 OSBPL1A IQSEC1 FGD1 PLEKHA1 PLCH1 CADPS2 PREX1 ACAP3

2.09e-0742612715IPR011993
DomainDH_1

TRIO KALRN PLEKHG4 ITSN1 FGD1 PREX1

4.34e-06631276PS00741
DomainGDS_CDC24_CS

TRIO PLEKHG4 ITSN1 FGD1 PREX1

6.43e-06391275IPR001331
DomainRhoGEF

TRIO KALRN PLEKHG4 ITSN1 FGD1 PREX1

6.81e-06681276SM00325
DomainRhoGEF

TRIO KALRN PLEKHG4 ITSN1 FGD1 PREX1

8.06e-06701276PF00621
DomainDH_2

TRIO KALRN PLEKHG4 ITSN1 FGD1 PREX1

8.06e-06701276PS50010
Domain-

TRIO KALRN PLEKHG4 ITSN1 FGD1 PREX1

8.76e-067112761.20.900.10
DomainDH-domain

TRIO KALRN PLEKHG4 ITSN1 FGD1 PREX1

8.76e-06711276IPR000219
DomainSH3_9

TSPOAP1 ITSN1 PACSIN3 RIMBP3 RIMBP3C RIMBP3B

1.51e-05781276PF14604
DomainGprotein_alpha_S

GNAL GNAS

4.59e-0521272IPR000367
DomainDUF3402

STRIP2 STRIP1

4.59e-0521272SM01293
DomainN1221

STRIP2 STRIP1

4.59e-0521272SM01292
DomainDUF3402

STRIP2 STRIP1

4.59e-0521272PF11882
DomainN1221

STRIP2 STRIP1

4.59e-0521272PF07923
DomainDUF3402

STRIP2 STRIP1

4.59e-0521272IPR021819
DomainN1221

STRIP2 STRIP1

4.59e-0521272IPR012486
DomainSH3

TRIO KALRN TSPOAP1 ITSN1 PACSIN3 RIMBP3 RIMBP3C RIMBP3B

1.16e-042161278SM00326
DomainSH3

TRIO KALRN TSPOAP1 ITSN1 PACSIN3 RIMBP3 RIMBP3C RIMBP3B

1.16e-042161278PS50002
Domain-

ARFGEF2 ARFGEF1 IQSEC1

1.32e-041512731.10.1000.11
DomainSec7

ARFGEF2 ARFGEF1 IQSEC1

1.32e-04151273PF01369
DomainSec7_alpha_orthog

ARFGEF2 ARFGEF1 IQSEC1

1.32e-04151273IPR023394
DomainSH3_domain

TRIO KALRN TSPOAP1 ITSN1 PACSIN3 RIMBP3 RIMBP3C RIMBP3B

1.32e-042201278IPR001452
DomainSEC7

ARFGEF2 ARFGEF1 IQSEC1

1.61e-04161273PS50190
DomainSec7

ARFGEF2 ARFGEF1 IQSEC1

1.61e-04161273SM00222
DomainSec7_dom

ARFGEF2 ARFGEF1 IQSEC1

1.61e-04161273IPR000904
DomainOAS1_C

OAS1 OAS3

2.73e-0441272PF10421
Domain2-5-oligoadenylate_synth_CS

OAS1 OAS3

2.73e-0441272IPR006117
DomainDCB_dom

ARFGEF2 ARFGEF1

2.73e-0441272IPR032629
Domain25A_SYNTH_3

OAS1 OAS3

2.73e-0441272PS50152
Domain2-5-oligoAdlate_synth_1_dom2/C

OAS1 OAS3

2.73e-0441272IPR018952
Domain2-5A_synthase

OAS1 OAS3

2.73e-0441272IPR026774
DomainSec7_C

ARFGEF2 ARFGEF1

2.73e-0441272IPR015403
DomainDUF1981

ARFGEF2 ARFGEF1

2.73e-0441272PF09324
Domain-

OAS1 OAS3

2.73e-04412721.10.1410.20
Domain25A_SYNTH_1

OAS1 OAS3

2.73e-0441272PS00832
Domain25A_SYNTH_2

OAS1 OAS3

2.73e-0441272PS00833
DomainSec7_N

ARFGEF2 ARFGEF1

2.73e-0441272IPR032691
DomainSec7_N

ARFGEF2 ARFGEF1

2.73e-0441272PF12783
DomainDCB

ARFGEF2 ARFGEF1

2.73e-0441272PF16213
DomainSH3_2

TSPOAP1 ITSN1 RIMBP3 RIMBP3C RIMBP3B

3.01e-04861275PF07653
DomainSH3_2

TSPOAP1 ITSN1 RIMBP3 RIMBP3C RIMBP3B

3.01e-04861275IPR011511
DomainRDM_domain_RFPL

RFPL1 RFPL2

4.53e-0451272IPR022723
Domain2-5-oligoadenylate_synth_N

OAS1 OAS3

4.53e-0451272IPR006116
DomainRDM

RFPL1 RFPL2

4.53e-0451272PF11002
DomainSpectrin

TRIO KALRN SPTBN5

4.92e-04231273PF00435
DomainCRAL-TRIO_dom

TRIO KALRN PLEKHG4

8.88e-04281273IPR001251
DomainZnF_UBR1

UBR2 UBR4

9.42e-0471272SM00396
DomainZF_UBR

UBR2 UBR4

9.42e-0471272PS51157
Domainzf-UBR

UBR2 UBR4

9.42e-0471272PF02207
DomainZnf_UBR

UBR2 UBR4

9.42e-0471272IPR003126
DomainSpectrin_repeat

TRIO KALRN SPTBN5

9.86e-04291273IPR002017
DomainSPEC

TRIO KALRN SPTBN5

1.32e-03321273SM00150
DomainSpectrin/alpha-actinin

TRIO KALRN SPTBN5

1.32e-03321273IPR018159
DomainFN3

KALRN TSPOAP1 RIMBP3 IGF1R RIMBP3C RIMBP3B

2.41e-031991276PS50853
DomainNTP_transf_2

OAS1 OAS3

2.42e-03111272PF01909
DomainPolymerase_NTP_transf_dom

OAS1 OAS3

2.42e-03111272IPR002934
DomainPRY

TRIM15 RFPL1 RFPL2

2.90e-03421273PF13765
DomainSPRY

TRIM15 RFPL1 RYR1 RFPL2

2.94e-03871274SM00449
DomainFN3_dom

KALRN TSPOAP1 RIMBP3 IGF1R RIMBP3C RIMBP3B

3.08e-032091276IPR003961
DomainSPRY

TRIM15 RFPL1 RYR1 RFPL2

3.88e-03941274PF00622
DomainSPRY_dom

TRIM15 RFPL1 RYR1 RFPL2

3.88e-03941274IPR003877
DomainB30.2/SPRY

TRIM15 RFPL1 RYR1 RFPL2

4.03e-03951274IPR001870
DomainB302_SPRY

TRIM15 RFPL1 RYR1 RFPL2

4.03e-03951274PS50188
DomainPRY

TRIM15 RFPL1 RFPL2

4.25e-03481273SM00589
DomainPRY

TRIM15 RFPL1 RFPL2

4.25e-03481273IPR006574
DomainGproteinA_insert

GNAL GNAS

5.17e-03161272IPR011025
Domain-

GNAL GNAS

5.17e-031612721.10.400.10
DomainG-alpha

GNAL GNAS

5.17e-03161272PF00503
DomainPINT

GPS1 COPS7B

5.17e-03161272SM00088
DomainG_alpha

GNAL GNAS

5.17e-03161272SM00275
DomainPCI_dom

GPS1 COPS7B

5.84e-03171272IPR000717
DomainGprotein_alpha_su

GNAL GNAS

5.84e-03171272IPR001019
DomainPCI

GPS1 COPS7B

5.84e-03171272PF01399
PathwayREACTOME_NRAGE_SIGNALS_DEATH_THROUGH_JNK

TRIO KALRN ITSN1 FGD1 PREX1

1.65e-0552875MM14743
PathwayREACTOME_NRAGE_SIGNALS_DEATH_THROUGH_JNK

TRIO KALRN ITSN1 FGD1 PREX1

3.07e-0559875M11215
PathwayREACTOME_CELL_DEATH_SIGNALLING_VIA_NRAGE_NRIF_AND_NADE

TRIO KALRN ITSN1 FGD1 PREX1

7.04e-0570875MM14824
PathwayREACTOME_CELL_DEATH_SIGNALLING_VIA_NRAGE_NRIF_AND_NADE

TRIO KALRN ITSN1 FGD1 PREX1

1.04e-0476875M19832
PathwayREACTOME_G_ALPHA_12_13_SIGNALLING_EVENTS

TRIO KALRN ITSN1 FGD1 PREX1

1.11e-0477875MM15044
PathwayREACTOME_G_ALPHA_12_13_SIGNALLING_EVENTS

TRIO KALRN ITSN1 FGD1 PREX1

1.33e-0480875M800
PathwayREACTOME_P75_NTR_RECEPTOR_MEDIATED_SIGNALLING

TRIO KALRN ITSN1 FGD1 PREX1

1.77e-0485875MM14746
PathwayWP_G_PROTEIN_SIGNALING_PATHWAYS

PDE4A ADCY5 PDE8B GNAL GNAS

2.32e-0490875MM15882
PathwayWP_G_PROTEIN_SIGNALING

PDE4A ADCY5 PDE8B GNAL GNAS

2.44e-0491875M39426
PathwayREACTOME_CDC42_GTPASE_CYCLE

TRIO DOCK11 ITSN1 FGD1 PREX1

2.84e-0494875MM15598
PathwayREACTOME_P75_NTR_RECEPTOR_MEDIATED_SIGNALLING

TRIO KALRN ITSN1 FGD1 PREX1

3.29e-0497875M9400
PathwayREACTOME_CDC42_GTPASE_CYCLE

TRIO PLEKHG4 DOCK11 ITSN1 FGD1 PREX1

3.89e-04155876M41808
Pubmed

Structure and evolution of RIM-BP genes: identification of a novel family member.

TSPOAP1 RIMBP3 RIMBP3C RIMBP3B

9.88e-105132417855024
Pubmed

Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method.

TPR PRAMEF7 STXBP4 ITSN1 DZIP1L CNTRL OAS1 CEP192 PRAMEF8 TTC3 KIAA0753 URB1 ALKBH8 AOPEP CEP112 PARD3 CCDC171 DEDD SLX4

3.05e-0810841321911544199
Pubmed

A central chaperone-like role for 14-3-3 proteins in human cells.

TRIO DOCK11 STXBP4 DCP2 CEP192 RASSF7 KIAA0753 FSIP2 IGF1R CEP112 XRN1 IQSEC1 PLEKHA1 GNAS PLCH1 PARD3 NOTCH2

3.17e-088611321736931259
Pubmed

RIM-BP3 is a manchette-associated protein essential for spermiogenesis.

RIMBP3 RIMBP3C RIMBP3B

2.13e-074132319091768
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

PDE4A TRIO KALRN MYO10 PHF12 UBR4 ARFGEF2 CEP192 GTF2IRD1 TTC3 RASSF7 RYR1 URB1 IGF1R ATP2A3 PREX1 SOWAHB NOTCH2

2.15e-0711051321835748872
Pubmed

Systematic analysis of human protein complexes identifies chromosome segregation proteins.

TPR CENPF STXBP4 DCP2 GPS1 PACSIN3 CEP192 STRIP1 DHX9 URB1 SF3B3 DCAF10 COPS7B KCTD2 GNAL GNAS SLX4 KNL1

4.09e-0711551321820360068
Pubmed

The deubiquitinase TRABID stabilizes the K29/K48-specific E3 ubiquitin ligase HECTD1.

UBR2 TRIO UBR4 ELP1 PDCD2L STRIP2 STRIP1 XRN1

1.61e-06212132833853758
Pubmed

Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.

UBR2 TRIO ZBTB8A CEP192 SKI GTF2IRD1 TTC3 SLC1A1 BRWD3 IGF1R AOPEP EXOC6B LRP1 GNAS PARD3 ZNF512 ERMARD NOTCH2 KLHL26

3.68e-0614891321928611215
Pubmed

Intersectin (ITSN) family of scaffolds function as molecular hubs in protein interaction networks.

TRIO ITSN1 PACSIN3 SYNC PDE4DIP PREX1

4.36e-06111132622558309
Pubmed

Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.

TRIO KALRN ITSN1 UBR4 ARFGEF2 SYNC TTC3 BRWD3 FAN1 SERPINE2 PDE4DIP OSBPL1A LRP1 MIGA1 CADPS2 PREX1 SLX4

7.85e-0612851321735914814
Pubmed

In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.

EFCAB5 CENPF ITSN1 DZIP1L CNTRL UBR4 GPS1 SKI TTC3 INSYN2A SF3B3 KIAA0825 CEP112 XRN1 PLCH1 CADPS2 ATP2A3 PREX1

9.16e-0614421321835575683
Pubmed

Activation of Rac GTPase by p75 is necessary for c-jun N-terminal kinase-mediated apoptosis.

KALRN ITSN1 FGD1 PREX1

1.32e-0538132411756498
Pubmed

Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.

STXBP4 ITSN1 UBR4 ELP1 CEP192 TTC3 KIAA0753 DHX9 URB1 SF3B3 PLEKHA1 GNAS DDHD2 FAR1 PLCH1 PARD3 ZNF512 NOTCH2

1.38e-0514871321833957083
Pubmed

Disruption of type 5 adenylyl cyclase negates the developmental increase in Galphaolf expression in the striatum.

ADCY5 GNAL

1.43e-052132215094058
Pubmed

Arf guanine nucleotide-exchange factors BIG1 and BIG2 regulate nonmuscle myosin IIA activity by anchoring myosin phosphatase complex.

ARFGEF2 ARFGEF1

1.43e-052132223918382
Pubmed

Regulation of brefeldin A-inhibited guanine nucleotide-exchange protein 1 (BIG1) and BIG2 activity via PKA and protein phosphatase 1gamma.

ARFGEF2 ARFGEF1

1.43e-052132217360629
Pubmed

Identification and localization of two brefeldin A-inhibited guanine nucleotide-exchange proteins for ADP-ribosylation factors in a macromolecular complex.

ARFGEF2 ARFGEF1

1.43e-052132210716990
Pubmed

Membrane association of the Arabidopsis ARF exchange factor GNOM involves interaction of conserved domains.

ARFGEF2 ARFGEF1

1.43e-052132218203920
Pubmed

High Anti-Dengue Virus Activity of the OAS Gene Family Is Associated With Increased Severity of Dengue.

OAS1 OAS3

1.43e-052132226063222
Pubmed

OAS1 and OAS3 negatively regulate the expression of chemokines and interferon-responsive genes in human macrophages.

OAS1 OAS3

1.43e-052132230078389
Pubmed

The human 2'-5'oligoadenylate synthetase family: unique interferon-inducible enzymes catalyzing 2'-5' instead of 3'-5' phosphodiester bond formation.

OAS1 OAS3

1.43e-052132217408844
Pubmed

Kalirin and Trio proteins serve critical roles in excitatory synaptic transmission and LTP.

TRIO KALRN

1.43e-052132226858404
Pubmed

Genome-wide DNA methylation profiling of chronic lymphocytic leukemia allows identification of epigenetically repressed molecular pathways with clinical impact.

ADCY5 BNC1

1.43e-052132220484983
Pubmed

Redundant roles of BIG2 and BIG1, guanine-nucleotide exchange factors for ADP-ribosylation factors in membrane traffic between the trans-Golgi network and endosomes.

ARFGEF2 ARFGEF1

1.43e-052132218417613
Pubmed

Far3 and five interacting proteins prevent premature recovery from pheromone arrest in the budding yeast Saccharomyces cerevisiae.

STRIP2 STRIP1

1.43e-052132212588993
Pubmed

Length dependent activation of OAS proteins by dsRNA.

OAS1 OAS3

1.43e-052132231629990
Pubmed

TORC2 signaling is antagonized by protein phosphatase 2A and the Far complex in Saccharomyces cerevisiae.

STRIP2 STRIP1

1.43e-052132222298706
Pubmed

Purification and cloning of a brefeldin A-inhibited guanine nucleotide-exchange protein for ADP-ribosylation factors.

ARFGEF2 ARFGEF1

1.43e-052132210212200
Pubmed

Phosphorylation of P-Rex1 at serine 1169 participates in IGF-1R signaling in breast cancer cells.

IGF1R PREX1

1.43e-052132223899556
Pubmed

Functional proteomics mapping of a human signaling pathway.

KIF18A ITSN1 PECAM1 UBR4 ARFGEF2 SKI TTC3 PDE4DIP LRP1 NOTCH2 KNL1

1.69e-055911321115231748
Pubmed

Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.

TPR PDE4A TRIO KALRN CENPF DOCK11 ITSN1 UBR4 TTC3 STRIP1 PDE4DIP IQSEC1 LRP1 PARD3

1.89e-059631321428671696
Pubmed

Integrative characterization of germ cell-specific genes from mouse spermatocyte UniGene library.

RIMBP3 RIMBP3C RIMBP3B

1.89e-0514132317662146
Pubmed

Cockayne syndrome group A and ferrochelatase finely tune ribosomal gene transcription and its response to UV irradiation.

GPS1 DHX9 SF3B3 COPS7B

1.98e-0542132434581821
Pubmed

NRAGE, a p75 neurotrophin receptor-interacting protein, induces caspase activation and cell death through a JNK-dependent mitochondrial pathway.

KALRN ITSN1 FGD1 PREX1

2.18e-0543132412376548
Pubmed

Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.

PHF12 OAS3 PDCD2L SKI BRWD3 SF3B3 XRN1 IQSEC1 LRP1 FAR1 PARD3 NOTCH2 KNL1 TCTN2 ARMC6

2.33e-0511161321531753913
Pubmed

New interaction partners for Nek4.1 and Nek4.2 isoforms: from the DNA damage response to RNA splicing.

TRIO FAM186B STRIP2 DHX9 NLRP14 SF3B3 ACAN XRN1 ADAMTS20 ATP2A3

2.80e-055131321025798074
Pubmed

Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.

TPR CENPF PHF12 UBR4 BRCA2 XRN1 LRP1 FAR1 KNL1

3.31e-05418132934709266
Pubmed

PIKES Analysis Reveals Response to Degraders and Key Regulatory Mechanisms of the CRL4 Network.

GPS1 BRWD3 DCAF10 COPS7B

3.68e-0549132431973889
Pubmed

Vegfa regulates perichondrial vascularity and osteoblast differentiation in bone development.

PECAM1 GNAS NOTCH2

4.18e-0518132325977369
Pubmed

The 2'-5'-oligoadenylate synthetase 3 enzyme potently synthesizes the 2'-5'-oligoadenylates required for RNase L activation.

OAS1 OAS3

4.28e-053132225275129
Pubmed

Interaction of Gsalpha with the cytosolic domains of mammalian adenylyl cyclase.

ADCY5 GNAS

4.28e-05313229268375
Pubmed

Specificity of binding of the low density lipoprotein receptor-related protein to different conformational states of the clade E serpins plasminogen activator inhibitor-1 and proteinase nexin-1.

SERPINE2 LRP1

4.28e-053132219439404
Pubmed

Interaction of phosphodiesterase 3A with brefeldin A-inhibited guanine nucleotide-exchange proteins BIG1 and BIG2 and effect on ARF1 activity.

ARFGEF2 ARFGEF1

4.28e-053132219332778
Pubmed

Specific functions of BIG1 and BIG2 in endomembrane organization.

ARFGEF2 ARFGEF1

4.28e-053132220360857
Pubmed

Synaptic Kalirin-7 and Trio Interactomes Reveal a GEF Protein-Dependent Neuroligin-1 Mechanism of Action.

TRIO KALRN

4.28e-053132231801062
Pubmed

The ribonuclease L-dependent antiviral roles of human 2',5'-oligoadenylate synthetase family members against hepatitis C virus.

OAS1 OAS3

4.28e-053132223196181
Pubmed

AMY-1 (associate of Myc-1) localization to the trans-Golgi network through interacting with BIG2, a guanine-nucleotide exchange factor for ADP-ribosylation factors.

ARFGEF2 ARFGEF1

4.28e-053132216866877
Pubmed

Association of Oligoadenylate Synthetase Gene Cluster and DC-SIGN (CD209) Gene Polymorphisms with Clinical Symptoms in Chikungunya Virus Infection.

OAS1 OAS3

4.28e-053132226398832
Pubmed

The human 2',5'-oligoadenylate synthetase locus is composed of three distinct genes clustered on chromosome 12q24.2 encoding the 100-, 69-, and 40-kDa forms.

OAS1 OAS3

4.28e-05313229790745
Pubmed

Evolutionary forces shape the human RFPL1,2,3 genes toward a role in neocortex development.

RFPL1 RFPL2

4.28e-053132218656177
Pubmed

Ric-8B is a GTP-dependent G protein alphas guanine nucleotide exchange factor.

GNAL GNAS

4.28e-053132221467038
Pubmed

The STRIPAK complex components FAM40A and FAM40B regulate endothelial cell contractility via ROCKs.

STRIP2 STRIP1

4.28e-053132230509168
Pubmed

Single-Cell Transcriptome Analysis Highlights a Role for Neutrophils and Inflammatory Macrophages in the Pathogenesis of Severe COVID-19.

OAS1 OAS3

4.28e-053132233138195
Pubmed

Involvement of BIG1 and BIG2 in regulating VEGF expression and angiogenesis.

ARFGEF2 ARFGEF1

4.28e-053132231199673
Pubmed

Polymorphisms in the oligoadenylate synthetase gene cluster and its association with clinical outcomes of dengue virus infection.

OAS1 OAS3

4.28e-053132223337612
Pubmed

Enhancement of β-catenin activity by BIG1 plus BIG2 via Arf activation and cAMP signals.

ARFGEF2 ARFGEF1

4.28e-053132227162341
Pubmed

The Sec7 guanine nucleotide exchange factor GBF1 regulates membrane recruitment of BIG1 and BIG2 guanine nucleotide exchange factors to the trans-Golgi network (TGN).

ARFGEF2 ARFGEF1

4.28e-053132223386609
Pubmed

The protein factor-arrest 11 (Far11) is essential for the toxicity of human caspase-10 in yeast and participates in the regulation of autophagy and the DNA damage signaling.

STRIP2 STRIP1

4.28e-053132222782902
Pubmed

Protease nexin 1 and its receptor LRP modulate SHH signalling during cerebellar development.

SERPINE2 LRP1

4.28e-053132217409116
Pubmed

Type 1 diabetes and the OAS gene cluster: association with splicing polymorphism or haplotype?

OAS1 OAS3

4.28e-053132216014697
Pubmed

OAS1, OAS2 and OAS3 restrict intracellular M. tb replication and enhance cytokine secretion.

OAS1 OAS3

4.28e-053132230822544
Pubmed

Adaptively introgressed Neandertal haplotype at the OAS locus functionally impacts innate immune responses in humans.

OAS1 OAS3

4.28e-053132227899133
Pubmed

A non-canonical GTPase interaction enables ORP1L-Rab7-RILP complex formation and late endosome positioning.

RILP OSBPL1A

4.28e-053132230012887
Pubmed

Identification of 69-kd and 100-kd forms of 2-5A synthetase in interferon-treated human cells by specific monoclonal antibodies.

OAS1 OAS3

4.28e-05313222440675
Pubmed

Structural basis of human ORP1-Rab7 interaction for the late-endosome and lysosome targeting.

RILP OSBPL1A

4.28e-053132230721249
Pubmed

A C-terminal sequence in the guanine nucleotide exchange factor Sec7 mediates Golgi association and interaction with the Rsp5 ubiquitin ligase.

ARFGEF2 ARFGEF1

4.28e-053132218832381
Pubmed

OAS1, OAS2, and OAS3 Contribute to Epidermal Keratinocyte Proliferation by Regulating Cell Cycle and Augmenting IFN-1‒Induced Jak1‒Signal Transducer and Activator of Transcription 1 Phosphorylation in Psoriasis.

OAS1 OAS3

4.28e-053132235305973
Pubmed

Identification of novel host cell binding partners of Oas1b, the protein conferring resistance to flavivirus-induced disease in mice.

OAS1 OSBPL1A

4.28e-053132222623793
Pubmed

Distinct functions for Arf guanine nucleotide exchange factors at the Golgi complex: GBF1 and BIGs are required for assembly and maintenance of the Golgi stack and trans-Golgi network, respectively.

ARFGEF2 ARFGEF1

4.28e-053132218003980
Pubmed

A crucial role for Arf6 in the response of commissural axons to Slit.

ARFGEF2 ARFGEF1 IQSEC1

4.95e-0519132330674481
Pubmed

Protein interaction network of the mammalian Hippo pathway reveals mechanisms of kinase-phosphatase interactions.

DOCK11 STXBP4 ELP1 CEP192 STRIP1 KIAA0753 PLEKHA1 PARD3 NOTCH2

5.47e-05446132924255178
Pubmed

CHK2 kinase promotes pre-mRNA splicing via phosphorylating CDK11(p110).

TPR UBR4 DHX9 SF3B3

5.82e-0555132423178491
Pubmed

DNA Repair Network Analysis Reveals Shieldin as a Key Regulator of NHEJ and PARP Inhibitor Sensitivity.

KIF18A MMS22L RBM45 CENPF PHF12 GTF2IRD1 BRCA2 SLX4 KNL1

6.16e-05453132929656893
Pubmed

Targeting TRIM37-driven centrosome dysfunction in 17q23-amplified breast cancer.

CEP192 KIAA0753 SF3B3 XRN1 LRP1 NOTCH2

7.62e-05184132632908313
Pubmed

Transcriptome analysis of mouse stem cells and early embryos.

PRAMEF7 MMS22L DOCK11 PRAMEF8 DHX9 PDE4DIP COPS7B FGD1

7.81e-05363132814691545
Pubmed

Ten years on: mediation of cell death by the common neurotrophin receptor p75(NTR).

KALRN ITSN1 FGD1 PREX1

8.20e-0560132412787561
Pubmed

USP7 Regulates Cytokinesis through FBXO38 and KIF20B.

KIF18A CENPF PDCD2L DEDD KNL1

8.35e-05116132530804394
Pubmed

The early embryonic expression of TFII-I during mouse preimplantation development.

PECAM1 GTF2IRD1

8.54e-054132214678824
Pubmed

Quality control of assembly-defective U1 snRNAs by decapping and 5'-to-3' exonucleolytic digestion.

DCP2 XRN1

8.54e-054132225071210
Pubmed

Gene structure of the murine 2'-5'-oligoadenylate synthetase family.

OAS1 OAS3

8.54e-054132212222967
Pubmed

Agonist-independent GPCR activity regulates anterior-posterior targeting of olfactory sensory neurons.

GNAL GNAS

8.54e-054132224034253
Pubmed

Human NB-2 of the contactin subgroup molecules: chromosomal localization of the gene (CNTN5) and distinct expression pattern from other subgroup members.

ARFGEF2 ARFGEF1

8.54e-054132211013081
Pubmed

A family of mammalian E3 ubiquitin ligases that contain the UBR box motif and recognize N-degrons.

UBR2 UBR4

8.54e-054132216055722
Pubmed

Interaction of FK506-binding protein 13 with brefeldin A-inhibited guanine nucleotide-exchange protein 1 (BIG1): effects of FK506.

ARFGEF2 ARFGEF1

8.54e-054132212606707
Pubmed

Protein kinase A-anchoring (AKAP) domains in brefeldin A-inhibited guanine nucleotide-exchange protein 2 (BIG2).

ARFGEF2 ARFGEF1

8.54e-054132212571360
Pubmed

Cholesterol sensor ORP1L contacts the ER protein VAP to control Rab7-RILP-p150 Glued and late endosome positioning.

RILP OSBPL1A

8.54e-054132219564404
Pubmed

Effects of brefeldin A-inhibited guanine nucleotide-exchange (BIG) 1 and KANK1 proteins on cell polarity and directed migration during wound healing.

ARFGEF2 ARFGEF1

8.54e-054132222084092
Pubmed

Distinct antiviral roles for human 2',5'-oligoadenylate synthetase family members against dengue virus infection.

OAS1 OAS3

8.54e-054132219923450
Pubmed

Notch2 is required for formation of the placental circulatory system, but not for cell-type specification in the developing mouse placenta.

PECAM1 NOTCH2

8.54e-054132217359302
Pubmed

Variability in the 2'-5'-oligoadenylate synthetase gene cluster is associated with human predisposition to tick-borne encephalitis virus-induced disease.

OAS1 OAS3

8.54e-054132221050126
Pubmed

Abnormalities of cAMP signaling are present in adrenocortical lesions associated with ACTH-independent Cushing syndrome despite the absence of mutations in known genes.

PDE8B GNAS

8.54e-054132219429701
Pubmed

Inactivation of C3a and C5a octapeptides by carboxypeptidase R and carboxypeptidase N.

CPN1 C5

8.54e-054132211939578
Pubmed

Lack of myotubularin (MTM1) leads to muscle hypotrophy through unbalanced regulation of the autophagy and ubiquitin-proteasome pathways.

RYR1 IGF1R

8.54e-054132223695157
Pubmed

The substrate recognition domains of the N-end rule pathway.

UBR2 UBR4

8.54e-054132219008229
Pubmed

LRP1 induces anti-PD-1 resistance by modulating the DLL4-NOTCH2-CCL2 axis and redirecting M2-like macrophage polarisation in bladder cancer.

LRP1 NOTCH2

8.54e-054132238462037
Pubmed

An essential role of N-terminal arginylation in cardiovascular development.

UBR2 PECAM1

8.54e-054132212098698
Pubmed

Golf: an olfactory neuron specific-G protein involved in odorant signal transduction.

GNAL GNAS

8.54e-05413222499043
Pubmed

Genome-wide CRISPR screens identify novel regulators of wild-type and mutant p53 stability.

STXBP4 ITSN1 ELP1 CEP192 RIMBP3 SF3B3 BRCA2 GNAS SLX4 KNL1

8.72e-055881321038580884
Pubmed

Majority of cerebrospinal fluid-contacting neurons in the spinal cord of C57Bl/6N mice is present in ectopic position unlike in other studied experimental mice strains and mammalian species.

STXBP4 ADCY5 PADI3

1.02e-0424132332212159
Pubmed

Large-scale mapping of human protein-protein interactions by mass spectrometry.

MMS22L UBR4 GPS1 PACSIN3 STRIP1 DHX9 IGF1R SF3B3 GNAS FAR1 PARD3 DEDD ATP2A3 PREX1 ARMC6

1.13e-0412841321517353931
GeneFamilyPleckstrin homology domain containing|Rho guanine nucleotide exchange factors|C2 domain containing

PLEKHG4 DOCK11 MYO10 ITSN1 FGD1 PLEKHA1 CADPS2 PREX1 ACAP3

8.65e-07206909682
GeneFamilyPleckstrin homology domain containing|Rho guanine nucleotide exchange factors|C2 domain containing

TRIO KALRN PLEKHG4 ITSN1 FGD1 PREX1

9.19e-0766906722
GeneFamilyUbiquitin protein ligase E3 component n-recognins

UBR2 UBR4

5.06e-047902785
GeneFamilyCOP9 signalosome

GPS1 COPS7B

8.62e-049902932
GeneFamilyArmadillo repeat containing|Protein phosphatase 1 regulatory subunits

KIF18A CEP192 RYR1 PARD3 KNL1

2.10e-03181905694
CoexpressionHALLMARK_MITOTIC_SPINDLE

TRIO CENPF ITSN1 CNTRL ARFGEF1 CEP192 BRCA2 PREX1 NOTCH2

7.93e-071991329M5893
ToppCelldroplet-Marrow-BM-30m-Lymphocytic-NK_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TSPOAP1 ARFGEF1 CSF1R KIAA0825 HPGD LRP1 ACAP3

6.05e-071641327b77995958c938e10a526118f75d78cee72e0b207
ToppCellT_cells-ISG-high_CD4+_T_cells|T_cells / Immune cells in Kidney/Urine in Lupus Nephritis

OAS1 OAS3 IFIT3 BRCA2 XRN1 DNAH9 RUFY4

1.09e-061791327af35ef8a7768cee0c2af0590e5bec35cee6a4714
ToppCelldroplet-Kidney-KIDNEY-30m-Lymphocytic-Epcam____thick_ascending_tube_S_epithelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KIF18A MMS22L CENPF STRIP2 ALKBH8 MIGA1 KNL1

1.09e-0617913274166c4e1a8748a79ac6a11fd0b97c5344be2321b
ToppCellB_cells-ABCs|B_cells / Immune cells in Rheumatoid Arthritis Joint Synovial Tissues

DOCK11 OAS1 OAS3 SYNC SLC1A1 IFIT3 KNL1

1.26e-061831327bf9c6fe3ce4e44e4056027257eab8448c39c4fb8
ToppCellPBMC-Control-Lymphocyte-T/NK-NK_cell-NK_activated|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

TSPOAP1 OAS3 IFIT3 STRIP2 FGD1 GNAL

1.43e-0611813265f72022f4be3fb7ccec86dc05d37572833028886
ToppCellPBMC-Control-Lymphocyte-T/NK-NK_cell-NK_activated-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

TSPOAP1 OAS3 IFIT3 STRIP2 FGD1 GNAL

1.43e-061181326053c0986051e36fdc4c48b8067c137b6299b2f1b
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Immune-Myeloid-Macrophage_Dendritic-Cycling_Mononuclear_Phagocyte|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

CENPF CNTRL RYR1 CSF1R BRCA2 PREX1 KNL1

1.46e-06187132773931a5ea73799095daff100b5f18853c57c74dc
ToppCellControl-Lymphoid_T/NK-NK_activated|Control / Disease group, lineage and cell class

TSPOAP1 OAS3 IFIT3 STRIP2 FGD1 GNAL

1.50e-061191326a258d91ac90d4174b6f203d7f96ba6e57c6003e7
ToppCellPBMC-Control-Lymphocyte-T/NK-NK_cell-NK_activated|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

TSPOAP1 OAS3 IFIT3 STRIP2 FGD1 GNAL

1.50e-06119132628d6b0e9dda2fe4ca94ae9b95b7261618d0d9877
ToppCellPBMC-Control-Lymphocyte-T/NK-NK_cell-NK_activated-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

TSPOAP1 OAS3 IFIT3 STRIP2 FGD1 GNAL

1.50e-0611913260fdd5b093ac20a4bda0f7b623808eb3ad0bf68e2
ToppCellpdx-Tumor_cells-T1|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)

KIF18A MMS22L CENPF CEP192 BRCA2 CEP112 KNL1

1.62e-061901327d06ee5f89f1cec8db6897fe3b2a890a07cd3697b
ToppCellhuman_hepatoblastoma-Tumor_cells-T1|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)

KIF18A MMS22L CENPF CEP192 BRCA2 CEP112 KNL1

1.80e-0619313274b9fa2a4424f8abe63fa7bee78db93dda04ab15f
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Immune-Myeloid-Macrophage_Dendritic-M2_Macrophage|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

DOCK11 ITSN1 RYR1 CSF1R KCNJ5-AS1 LRP1 PREX1

1.86e-06194132745708cb2cafde10bf4e4798b81d47c3b1f6aaa14
ToppCelldroplet-Marrow-BM_(NON-STC)-30m-Lymphocytic-NK_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RYR1 CSF1R HPGD LRP1 CADPS2 RUFY4

6.21e-06152132682a493ffb2f1704cd6f68a82d970fe12f537d20e
ToppCellCOVID-CD4-antiviral_CD4|COVID / Condition, Cell_class and T cell subcluster

MYO10 OAS3 IFIT3 CACNA1I RUFY4 KNL1

6.95e-0615513267e5ae034036fe85915d38a24195501e6d3bcbfb0
ToppCellNS-moderate-d_07-13-Epithelial-FOXN4+|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

CENPF DZIP1L BRCA2 KIAA0825 CEP112 CCDC171

7.48e-061571326410c9d74a2085179cfb39853cb6d330fa98c9c1b
ToppCellfacs-Marrow-B-cells-24m-Myeloid-basophil|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SKI RASSF7 SERPINE2 ABCD4 KCTD2 ZNF512

1.03e-05166132613027ae342994db4540e64eb910df1f42b160931
ToppCellfacs-Marrow-B-cells-24m-Myeloid-basophil|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SKI RASSF7 SERPINE2 ABCD4 KCTD2 ZNF512

1.03e-051661326b21e45bd43f26149b9cd6e45c19241c82d54fb2f
ToppCellTCGA-Cervix-Primary_Tumor-Cervical_Carcinoma-Non-keratinizing_Cervical_Squamous_Cell_Carcinoma-3|TCGA-Cervix / Sample_Type by Project: Shred V9

XRN1 LRP1 PLEKHA1 PARD3 SOWAHB PADI3

1.39e-0517513260cc215109d9915af47e4d0a120ce2e46910715fa
ToppCellSevere-CD4+_T_activated|Severe / Disease group and Cell class

OAS1 OAS3 IFIT3 XRN1 DNAH9 RFPL2

1.48e-051771326a08f170f1143fcdd7d0842a54d9b807a4548f8b7
ToppCellSevere-CD4+_T_activated|World / Disease group and Cell class

OAS1 OAS3 IFIT3 XRN1 DNAH9 RFPL2

1.53e-051781326ef6111238703579a34bd6948bd9d4ca6b7e16063
ToppCellChildren_(3_yrs)-Mesenchymal-pericyte_cell-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

KALRN MYO10 STXBP4 ADCY5 CSF1R PARD3

2.02e-05187132686250acf088ec0c4800a0dfa031b0d4f7e52c342
ToppCell368C-Epithelial_cells-Epithelial-I_(AT1)-|368C / Donor, Lineage, Cell class and subclass (all cells)

TRPV1 PACSIN3 OAS3 KCTD2 CADPS2 KLHL26

2.08e-051881326c74771584b3ba9561a99a54bf55a9203ddf8eff8
ToppCell368C-Epithelial_cells-Epithelial-I_(AT1)|368C / Donor, Lineage, Cell class and subclass (all cells)

TRPV1 PACSIN3 OAS3 KCTD2 CADPS2 KLHL26

2.08e-0518813269155b9a92496e75646778c025b02947e9e9ec73a
ToppCellMacrophages-Cryobiopsy_01|World / lung cells shred on cell class, cell subclass, sample id

DOCK11 PECAM1 IFIT3 CSF1R IQSEC1 LRP1

2.14e-051891326c05b4b565c0ce56dbb45fc9503654a2ec1a7e1e9
ToppCellCD8+_Memory_T_cell-CV-7|CD8+_Memory_T_cell / cell class, Virus stimulation and cluster

UBR2 MMS22L ARFGEF2 URB1 KCNJ5-AS1 FAR1

2.27e-0519113269454f642c3621370fa23640b631301346b300950
ToppCellRV-08._Macrophage|World / Chamber and Cluster_Paper

CENPF DOCK11 CSF1R BRCA2 PREX1 KNL1

2.34e-051921326a1b5dc5beb97a23729b97b54fb4574d10d8fbfb3
ToppCellRV-08._Macrophage|RV / Chamber and Cluster_Paper

CENPF DOCK11 CSF1R BRCA2 PREX1 KNL1

2.41e-05193132612bf98a280f87e4d8f0c6887dfc855da72e47ac1
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Immune-Myeloid-Macrophage_Dendritic-M2_Macrophage|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

DOCK11 ITSN1 CNTRL RYR1 CSF1R PREX1

2.48e-051941326c95d5c4ad0210ebd672926558cc8331e6396a854
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Immune-Myeloid-Macrophage_Dendritic|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

DOCK11 ITSN1 RYR1 CSF1R LRP1 PREX1

2.55e-051951326247803cf58c6d9c561a52aa34e581188ddad197e
ToppCell10x_3'_v2v3-Non-neoplastic-Myeloid-TAM-BDM-TAM-BDM_INF|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

PECAM1 OAS1 OAS3 IFIT3 OLFML3 CSF1R

2.63e-051961326efdc95811e8b17243065ae82d748ea2c5775fdbc
ToppCellBrain_organoid-organoid_Paulsen_bioRxiv-3.5_mon-Proliferating-Cycling_Progenitors|3.5_mon / Sample Type, Dataset, Time_group, and Cell type.

KIF18A MMS22L CENPF BRCA2 NOTCH2 KNL1

2.63e-0519613265905f0e3061a6b98b7a33d64c782c3dda2cd51ef
ToppCell10x_3'_v2v3-Non-neoplastic-Myeloid-TAM-BDM-TAM-BDM_INF-Z|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

PECAM1 OAS1 OAS3 IFIT3 OLFML3 CSF1R

2.63e-0519613263392efa5007736b1e87f34805c16e8baa792e596
ToppCellParenchymal-NucSeq|Parenchymal / Cell types per location group and 10X technology with lineage, and cell group designations

TRIO IGF1R AOPEP EXOC6B PARD3 CADPS2

2.78e-0519813261996373bdccc55aac347d349bd22f6aad6d0c668
ToppCell10x_3'_v2v3-Neoplastic-Differentiated-like-AC-like-AC-like_Prolif-E|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

KIF18A CENPF INSYN2A BRCA2 GNAS KNL1

2.78e-0519813267225a6194c52b01c581e58d3cda107c4af96dc4f
ToppCellControl-NK_activated|Control / Disease condition and Cell class

OAS1 OAS3 IFIT3 STRIP2 GNAL

2.81e-0511913250d0bab03d56e269c6e637b0bbeffe9d1491dfc33
ToppCellControl_saline|World / Treatment groups by lineage, cell group, cell type

PECAM1 SERPINE2 HPGD PLEKHA1 GNAS ATP2A3

2.86e-05199132611c9c1779caceb725ecccf3f23b7d4e6dbd1af64
ToppCell(09)_Interm._secr.>cil.-(2)_GFP_FOXI1|(09)_Interm._secr.>cil. / shred by cell type by condition

TPR ITSN1 CNTRL TTC3 HPGD OSBPL1A

2.86e-051991326fc680f85ebd3bab4c72876a19a461b0afb5f51ce
ToppCellCOVID-19_Severe-immature_Neutrophil|COVID-19_Severe / Disease condition and Cell class

MMS22L CENPF IGF1R BRCA2 ATP2A3 KNL1

2.86e-051991326f82fa9d651e78f9ebbe6264e00a48c54b1786a69
ToppCellTracheal-NucSeq|Tracheal / Cell types per location group and 10X technology with lineage, and cell group designations

UBR2 TRIO IGF1R EXOC6B PARD3 CADPS2

2.86e-05199132694b94b17ca18b8dc27b91da1f2ccf89e03cc7035
ToppCellCOVID-19_Severe-immature_Neutrophil-|COVID-19_Severe / Disease condition and Cell class

MMS22L CENPF IGF1R BRCA2 ATP2A3 KNL1

2.86e-05199132642ea0c19c455bdb0ae89b428d09c333104c670dc
ToppCellLPS_IL1RA-Endothelial-Endothelial-FOXM1|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

KIF18A MMS22L CENPF CNTRL BRCA2 KNL1

2.86e-051991326be2276c9a1994579ba1d2998b49bf549c1324d44
ToppCellControl_saline-Endothelial-Endothelial-FOXM1|Control_saline / Treatment groups by lineage, cell group, cell type

KIF18A CENPF CNTRL BRCA2 ACAN KNL1

2.94e-0520013269bbc7b5561151f6ff65f40b3226271def732e5d9
ToppCellLPS_only-Endothelial-Endothelial-Activated_Alv_Cap|LPS_only / Treatment groups by lineage, cell group, cell type

PECAM1 OAS1 OAS3 IFIT3 HPGD XRN1

2.94e-052001326edb64556b3fefe3144f73b6efe23b9ffd34091d2
ToppCellLPS_IL1RA_TNF-Endothelial-Endothelial-Activated_Alv_Cap|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

PECAM1 OAS1 OAS3 IFIT3 HPGD XRN1

2.94e-05200132689821a264e872ed53e08e9d3609d5cc5c314503e
ToppCellmild|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

TPR UBR2 OAS1 OAS3 IFIT3 XRN1

2.94e-05200132612f1685ce8f218433068e090c9d839cd5a1910bf
ToppCellsevere-immature_Neutrophil|severe / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

CENPF DZIP1L IGF1R BRCA2 OSBPL1A ATP2A3

2.94e-052001326a9b87accdaa6956116ab82427e1330e8f007ef94
ToppCell368C-Epithelial_cells-Epithelial-I_(AT1)-|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

TRPV1 OAS1 OAS3 KCTD2 KLHL26

5.91e-05139132539f3c28f89c37bb8cc049c56d2948ea906fb3d86
ToppCell368C-Epithelial_cells-Epithelial-I_(AT1)|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

TRPV1 OAS1 OAS3 KCTD2 KLHL26

5.91e-0513913254efab4421e3448880a1dcf981f6a65131b038010
ToppCell10x5'-Lung-Lymphocytic_T_CD4-T_CD4/CD8|Lung / Manually curated celltypes from each tissue

FAM186B CEP112 FGD1 PLCH1 DNAH9

1.02e-04156132510d191e29b16cae8238e8df6c0ff38882253f34e
ToppCelldroplet-Marrow-nan-18m-Lymphocytic-NK_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EFCAB5 RYR1 CSF1R HPGD COPS7B

1.18e-0416113253f3a2148c8d65e6a06f8d8116a3aa58dda17d618
ToppCellLPS-antiTNF-Endothelial-Endothelial-FOXM1|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

KIF18A MMS22L CENPF BRCA2 KNL1

1.25e-0416313255285318c52aa31c9b22dc2ffff078e32e408604d
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_G2M|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

KIF18A CENPF BRCA2 ACAN KNL1

1.33e-041651325eec2d327c94832d1390314c93ef6a2be4648478b
ToppCellCOVID-CD8-exh_CD4|COVID / Condition, Cell_class and T cell subcluster

SERPINE2 KIAA0825 DCAF10 FBXL20 KLHL26

1.36e-0416613254ca8c91b03d08489f244898cf9423b9d10348bc8
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell_cycling-Cycling_Connecting_Tubule_Cell_S-high|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

MMS22L STRIP2 SPTBN5 BRCA2 KNL1

1.40e-041671325108ae6221c6edc63c0ec42c42471b3a15a594043
ToppCellPND10-Immune-Immune_Myeloid-DC-cDC2-cDC2_G2M|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CENPF DCP2 CEP192 INSYN2A KNL1

1.44e-0416813254c402a1613fcf0a6e4d9b9d5551812940e91ff32
ToppCelldroplet-Marrow-nan-24m-Lymphocytic-NK_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KALRN CSF1R HPGD LRP1 ATP2A3

1.44e-041681325e979a4fbeb9f21048b47d69e6da75c57650697f2
ToppCelldroplet-Thymus-nan-24m-Lymphocytic-DN_to_DP_transition,_dividing_(more_DN)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ARFGEF2 STRIP2 IGF1R AOPEP FGD1

1.44e-041681325b9db0b1e4fe54a1fe79530d15d206155a1bfac39
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_G2M|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

KIF18A CENPF BRCA2 SOWAHB KNL1

1.48e-041691325b253a4a50c06d36228fcd5d856c57202cbac158f
ToppCellLPS-IL1RA+antiTNF-Endothelial-Endothelial-FOXM1|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

KIF18A MMS22L CENPF BRCA2 KNL1

1.48e-041691325e0607af8ae8609d43e26ff2a2cab92650bfcd5b7
ToppCellnormal_Pleural_Fluid-Myeloid_cells-CD163+CD14+_DCs|Myeloid_cells / Location, Cell class and cell subclass

STXBP4 PACSIN3 FSIP2 URB1 PLEKHA1

1.48e-041691325bea8aba1f3cc3d0e8d448c1c45f5354d26ebf850
ToppCellTCGA-Brain-Primary_Tumor-Low_Grade_Glioma-Astrocytoma-10|TCGA-Brain / Sample_Type by Project: Shred V9

SYNC CEP112 KCNJ5-AS1 DNAH9 NEK11

1.57e-04171132574be8d3bf6b99e2d734635a8b1a7c41e8c596959
ToppCellprimary_auditory_cortex_(A1C)|World / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

MYO10 PLCH1 PARD3 PREX1 TCTN2

1.61e-04172132520ea9db009370aa6235365ce93e153eb5b28db94
ToppCell10x5'-bone_marrow-Myeloid_Mac-Intestinal_macrophages|bone_marrow / Manually curated celltypes from each tissue

OLFML3 RIMBP3 SPTBN5 CSF1R LRP1

1.70e-0417413250746344d62aa7ab77c378e9d5a9f9238e741a76b
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_G2M|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

KIF18A CENPF BRCA2 C22orf39 KNL1

1.70e-041741325dbb4e1a6c3319ce40f81bfd2d1745a88a2cc412e
ToppCell3'-Distal_airway-Epithelial-Airway_epithelium-respiratory_basal_cell-Suprabasal-Suprabasal_L.0.0.1.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CENPF BRCA2 AOPEP PADI3 KNL1

1.70e-04174132546cbb462173a684ceb9e680f9259dc3b133763f7
ToppCellsaliva-Severe-critical_progression_d28-40-Myeloid-Granulocytic-Neutrophil-Neu_c4-RSAD2|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)

CNTRL OAS1 OAS3 IFIT3 XRN1

1.75e-04175132597616bb5c127284aa9e67bc336dfcf29e137164b
ToppCelldroplet-Marrow-nan-3m-Lymphocytic-NK_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DOCK11 ARFGEF1 CSF1R HPGD LRP1

1.75e-041751325cf53a15bfb37b6019e7052ffdf594a9ac040900e
ToppCellCOVID-19_Mild-Neu_3|COVID-19_Mild / 5 Neutrophil clusters in COVID-19 patients

ELP1 OAS3 XRN1 SLX4 RUFY4

1.79e-0417613252049767fd591045cfcf5b1071d80798e52843f27
ToppCellRV-11._Adipocyte|World / Chamber and Cluster_Paper

PLIN4 DOCK11 ITSN1 PDE8B OSBPL1A

1.84e-041771325f0edf04930692418953e4f00a917257804ec0ffd
ToppCelldroplet-Marrow-BM-1m-Lymphocytic-plasma_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYO10 CSF1R HPGD PDE4DIP LRP1

1.84e-04177132526bad614560609d318bfc9c235a698bca4e1c22c
ToppCellPND03-Endothelial-Endothelial_blood-vessel-Microvascular_EC-EPC-EPC_prolif|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MMS22L CENPF PECAM1 HPGD KNL1

1.84e-0417713258a74f5e72de605774111057bd87a7e7e4a6385cd
ToppCelldroplet-Limb_Muscle-MUSCLE-30m|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TPR MYO10 CNTRL IFIT3 XRN1

1.89e-04178132501dafd19de04eff459253eaa9a35debf8f3deedf
ToppCellRV-11._Adipocyte|RV / Chamber and Cluster_Paper

PLIN4 DOCK11 ITSN1 PDE8B OSBPL1A

1.89e-041781325278bbea5cf8f0589f71675c7a3d00679391b5253
ToppCell5'-Airway_Nasal-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell-Deuterosomal|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CENPF CNTRL BRCA2 RIMBP3C CCDC171

1.94e-041791325d15182c668d7c37be8214cad9f1fe35d1409c9a1
ToppCell5'-Airway_Nasal-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell-Deuterosomal-Deuterosomal_L.0.3.4.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CENPF CNTRL BRCA2 RIMBP3C CCDC171

1.94e-041791325e22a275a7c0ed19113c833a75d6c49fcc19aa13a
ToppCell3'_v3-bone_marrow-Myeloid_Mac-Erythrophagocytic_macrophages|bone_marrow / Manually curated celltypes from each tissue

OAS1 OLFML3 CSF1R OSBPL1A EXOC6B

1.99e-041801325daf69a548ed7c6f285a6adcff00f99aa22f9d6a5
ToppCellLPS-IL1RA-Endothelial-Endothelial-FOXM1|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

KIF18A MMS22L CENPF BRCA2 KNL1

1.99e-041801325334e2b1f6eb7d4ece20b1c7b02107863f913237f
ToppCellfacs-Liver-Hepatocytes-24m-Epithelial|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PACSIN3 CPN1 SERPINE2 AFM PARD3

2.09e-041821325770ce9f3f4538d0181a0181543841bc964c68274
ToppCelldroplet-Thymus-nan-24m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KIF18A CENPF PDE8B FGD1 SLX4

2.09e-04182132539f9b3eb22293cc27c6e175702c77d1eeb24fdc9
ToppCellfacs-Liver-Hepatocytes-24m-Epithelial-nan|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PACSIN3 CPN1 SERPINE2 AFM PARD3

2.09e-04182132577ab860e2add49dad0c1ffbfc64278ad499dfbd5
ToppCellfacs-Liver-Hepatocytes-24m-Epithelial-hepatocyte|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PACSIN3 CPN1 SERPINE2 AFM PARD3

2.09e-0418213254921c7d5687cc79f896b39753bb621d7e3d2972f
ToppCellCalu_3-infected|Calu_3 / Cell line, Condition and Strain

TRIO OAS1 OAS3 IFIT3 XRN1

2.15e-0418313258f7f5000645f24f20a8d7700c4df1f8953a1780b
ToppCellB_cells-ISG-high_B_cells|World / Immune cells in Kidney/Urine in Lupus Nephritis

OAS1 OAS3 IFIT3 BRCA2 XRN1

2.15e-041831325dc2b00e920efa1dcc2a6265cd1024e3249c9974f
ToppCellRSV-Healthy-5|Healthy / Virus stimulation, Condition and Cluster

OAS1 OAS3 RILP IFIT3 HPGD

2.20e-0418413251e282d619ef8035437fabe0fd2aefda1c142f7f6
ToppCellRSV-Healthy-5|RSV / Virus stimulation, Condition and Cluster

OAS1 OAS3 RILP IFIT3 HPGD

2.20e-041841325ba958f731de6c9eff60103d483e020e2c0c7af7c
ToppCellDendritic_Cells-IPF_04|World / lung cells shred on cell class, cell subclass, sample id

CENPF OLFML3 RUFY4 KNL1

2.23e-041001324bb7bd11e28be830f381144d4a6f29a86da59d9fa
ToppCell3'_v3-lymph-node_spleen-Hematopoietic_progenitors-Cycling_pre-Myeloid-2|lymph-node_spleen / Manually curated celltypes from each tissue

CENPF ITSN1 IGF1R OSBPL1A ERMARD

2.37e-0418713253c10b8501226c69d71bcd99dc1c064a3c2154f87
ToppCell(2)_5-FU-(2)_LEPR+_perivascular_cells_and_VE-Cad+_vascular_cells_(mixed)|(2)_5-FU / Stress and Cell class

CENPF OLFML3 SERPINE2 HPGD LRP1

2.37e-0418713256bbf0f7fe203274dae8d582652f35cd3187c0065
ToppCellLPS-IL1RA+antiTNF-Endothelial-Endothelial-Activated_Alv_Cap|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PECAM1 OAS1 OAS3 IFIT3 HPGD

2.37e-041871325f3397dbc23b6c2f24e2c1ba887d8f9aef3ee01a1
ToppCellcritical-Myeloid-Monocyte-derived_Macrophage|Myeloid / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

CNTRL OAS1 OAS3 IFIT3 XRN1

2.37e-04187132572e4aec49ea0c5fe6cee2a1a46369dbc90cd3fad
ToppCellLA-03._Atrial_Cardiomyocyte|World / Chamber and Cluster_Paper

GTF2IRD1 IGF1R PDE8B PDE4DIP EXOC6B

2.43e-0418813256d249fe92d51a19da19ec14bb2262d394255d577
ToppCellT_cells-ISG-high_CD4+_T_cells|World / Immune cells in Kidney/Urine in Lupus Nephritis

OAS1 OAS3 IFIT3 XRN1 RUFY4

2.43e-0418813256f8946d4710f6e32c937213f99b790b098b8819c
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-3m-Macroglial-oligodendrocyte_precursor_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TRIO RIMBP3 SERPINE2 LRP1 ACAP3

2.43e-041881325a244fcd092d5bd544e503366b1439b0fbc1ee00e
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-3m-Macroglial-Oligodendrocyte_progenitor_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TRIO RIMBP3 SERPINE2 LRP1 ACAP3

2.43e-041881325c8530c9ff98666c64a94683261af4288cb790a7e
ToppCellnucseq-Endothelial-Endothelial_Vascular-Endothelial_capillary-CAP2|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

KALRN PECAM1 HPGD CADPS2 PREX1

2.49e-041891325b6b4da51bc7f2c13a2f940540fdc61027d084835
ToppCellControl-B_intermediate-6|Control / disease group and sub_cluster of B and Plasma cells(res = 0.5)

UBR4 OAS1 IQSEC1 ATP2A3 PREX1

2.49e-04189132511cb9a16f1de8f60af2073ed7ea6d4f41c02f299
ToppCellControl-Endothelial-Endothelial-FOXM1|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

KIF18A MMS22L CENPF BRCA2 KNL1

2.49e-0418913251e1499b062d9c647c8f38b0c4e0d871d159be5dd
ToppCellNS-critical-d_07-13-Epithelial-FOXN4+|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

KIF18A CENPF BRCA2 GNAL CCDC171

2.55e-0419013257be0f2ff86ca8500a43e0d44e5e292530f9ba0bb
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Cycling_Endothelial_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

MMS22L CENPF PECAM1 BRCA2 KNL1

2.55e-04190132531de1727822e9818652946dfb962daee77ffad68
Drugirinotecan HCl; Down 200; 100uM; MCF7; HT_HG-U133A

KIF18A TRIO CENPF MYO10 ITSN1 GTF2IRD1 IGF1R PLCH1 PARD3

6.75e-0717412997530_DN
DrugNortriptyline hydrochloride [894-71-3]; Up 200; 13.4uM; PC3; HT_HG-U133A

TRIO OAS1 IGF1R ACAN EXOC6B LRP1 CADPS2 NEK11

1.64e-0519612987300_UP
DrugDiprophylline [479-18-5]; Up 200; 15.8uM; MCF7; HT_HG-U133A

CNTRL OAS3 SLC1A1 CSF1R CEP112 HPGD ACAN ADAMTS20

1.70e-0519712985482_UP
Drug11-deoxy-16,16-dimethyl Prostaglandin E2; Up 200; 10uM; MCF7; HT_HG-U133A

TRIO CSF1R PDE8B PDE4DIP FGD1 GNAS ATP2A3 PADI3

1.70e-0519712987533_UP
DrugPilocarpine nitrate [148-72-1]; Down 200; 14.8uM; PC3; HT_HG-U133A

PDE8B ABCD4 GNAS PLCH1 CADPS2 NOTCH2 ARMC6 KLHL26

1.70e-0519712986741_DN
Drugtroglitazone; Up 200; 10uM; HL60; HT_HG-U133A

ITSN1 ELP1 IFIT3 ACAN IQSEC1 PLEKHA1 PARD3 TCTN2

1.70e-0519712981173_UP
DrugDroperidol [548-73-2]; Up 200; 10.6uM; PC3; HT_HG-U133A

PDE4A KALRN ELP1 KIAA0753 SPTBN5 URB1 LRP1 GNAL

1.70e-0519712984629_UP
DrugThiethylperazine malate [52239-63-1]; Up 200; 6uM; HL60; HT_HG-U133A

TRPV1 URB1 PDE4DIP ABCD4 IQSEC1 FGD1 PARD3 NEK11

1.76e-0519812986154_UP
DrugSTOCK1N-28457; Up 200; 20uM; MCF7; HT_HG-U133A

PDE4A MYO10 SYNC CSF1R PARD3 ATP2A3 NEK11 NOTCH2

1.83e-0519912986869_UP
DiseaseMalignant neoplasm of breast

KALRN CENPF STXBP4 UBR4 ARFGEF2 ELP1 TTC3 NLRP14 SERPINE2 IGF1R ALKBH8 CSF1R BRCA2 ATP2A3 DNAH9 NOTCH2 PADI3

2.41e-06107412317C0006142
Diseasescoliosis (is_implicated_in)

ELP1 TPH1

1.03e-0441232DOID:0060249 (is_implicated_in)
DiseaseMEDULLOBLASTOMA

ELP1 BRCA2

2.56e-0461232155255
Diseaseperiventricular nodular heterotopia (is_implicated_in)

ARFGEF2 ERMARD

2.56e-0461232DOID:0050454 (is_implicated_in)
DiseaseMedulloblastoma

ELP1 BRCA2

2.56e-0461232cv:C0025149
Diseasebirth weight

CENPF ARFGEF2 ADCY5 IGF1R XRN1 PLEKHA1 MIGA1 PREX1

2.78e-043991238EFO_0004344
Diseaseinfertility (implicated_via_orthology)

CSF1R BRCA2

3.57e-0471232DOID:5223 (implicated_via_orthology)
DiseasePeriventricular Nodular Heterotopia

ARFGEF2 ERMARD

3.57e-0471232C1868720
DiseaseGlioma

ELP1 BRCA2

6.09e-0491232cv:C0017638
Diseaseepilepsy (implicated_via_orthology)

TRIO KALRN SLC1A1 DHX9 LRP1

6.19e-041631235DOID:1826 (implicated_via_orthology)
Diseasemedulloblastoma (is_implicated_in)

ELP1 BRCA2

7.59e-04101232DOID:0050902 (is_implicated_in)
Diseaseneuroblastoma (is_implicated_in)

PECAM1 IGF1R

7.59e-04101232DOID:769 (is_implicated_in)
Diseasebirth weight, parental genotype effect measurement

ARFGEF2 ADCY5 IGF1R PLEKHA1 PREX1

1.29e-031921235EFO_0004344, EFO_0005939
DiseaseInfluenza

OAS1 OAS3 IFIT3

1.35e-03521233C0021400
Diseasedystonia (is_implicated_in)

TSPOAP1 AOPEP

1.52e-03141232DOID:543 (is_implicated_in)
Diseasenephroblastoma (is_implicated_in)

IGF1R BRCA2

1.52e-03141232DOID:2154 (is_implicated_in)
DiseaseFanconi anemia

BRCA2 SLX4

1.52e-03141232cv:C0015625
DiseaseFEV change measurement, response to corticosteroid

KIAA0825 PLCH1

1.52e-03141232EFO_0005921, GO_0031960
DiseaseMammary Carcinoma, Human

CENPF STXBP4 ELP1 IGF1R ALKBH8 CSF1R BRCA2 NOTCH2

1.64e-035251238C4704874
DiseaseMammary Neoplasms, Human

CENPF STXBP4 ELP1 IGF1R ALKBH8 CSF1R BRCA2 NOTCH2

1.64e-035251238C1257931
DiseaseMammary Neoplasms

CENPF STXBP4 ELP1 IGF1R ALKBH8 CSF1R BRCA2 NOTCH2

1.68e-035271238C1458155
Diseasebrain edema (biomarker_via_orthology)

SERPINE2 C5

1.75e-03151232DOID:4724 (biomarker_via_orthology)
Diseaseinfant head circumference

ARFGEF2 PREX1

1.75e-03151232EFO_0004577
Diseasevitamin K-dependent protein C measurement

SF3B3 PARD3

1.75e-03151232EFO_0008318
DiseaseBreast Carcinoma

CENPF STXBP4 ELP1 IGF1R ALKBH8 CSF1R BRCA2 NOTCH2

1.92e-035381238C0678222
Diseasewaist circumference

TRIO STXBP4 DCP2 MIGA1 CADPS2 PREX1 PADI3

2.19e-034291237EFO_0004342
DiseaseAlzheimer's disease (is_implicated_in)

SERPINE2 XRN1 LRP1 TPH1

2.30e-031321234DOID:10652 (is_implicated_in)
Diseasesusceptibility to hepatitis B infection measurement

ARFGEF2 KCTD2 PREX1

2.45e-03641233EFO_0008405
DiseaseBone marrow hypocellularity

BRCA2 SLX4

2.52e-03181232C1855710
DiseaseMYELODYSPLASTIC SYNDROME

CSF1R BRCA2 SLX4

2.79e-03671233C3463824
Diseaseage-related macular degeneration, COVID-19

OAS1 CPN1 PLEKHA1

3.03e-03691233EFO_0001365, MONDO_0100096
Diseaseosteoarthritis (biomarker_via_orthology)

PECAM1 ACAN

3.44e-03211232DOID:8398 (biomarker_via_orthology)
Diseasebehavioural disinhibition measurement

CACNA1I GNAL DNAH9

3.84e-03751233EFO_0006946
DiseaseEpilepsy, Benign Psychomotor, Childhood

TRPV1 SLC1A1

4.12e-03231232C0393672
DiseaseEpilepsy, Lateral Temporal

TRPV1 SLC1A1

4.12e-03231232C0393682
Diseasesphingomyelin 24:1 measurement

MMS22L IGF1R

4.12e-03231232EFO_0010398
DiseaseUncinate Epilepsy

TRPV1 SLC1A1

4.12e-03231232C0014558
DiseaseEpilepsy, Temporal Lobe

TRPV1 SLC1A1

4.12e-03231232C0014556

Protein segments in the cluster

PeptideGeneStartEntry
RNAEAQQSLCESERA

C22orf39

96

Q6P5X5
QATQAQNECRKLRDE

CNTRL

631

Q7Z7A1
AANDSVCRLQQREQE

BLOC1S5

111

Q8TDH9
DQRNQLLEVDFCIGR

COPS7B

146

Q9H9Q2
QNLVDICRERQFQAF

ALKBH8

436

Q96BT7
ICRERQFQAFVCDAL

ALKBH8

441

Q96BT7
CQSQNEELQRKTDRF

AFM

536

P43652
CDLNAANIFERLVND

ARFGEF1

571

Q9Y6D6
SRLAIRNEFCQEVVD

ARMC6

301

Q6NXE6
CALSTQRDFLQEQVN

CCDC171

746

Q6TFL3
LARQIEENRFQCDIC

BNC1

711

Q01954
DCDLNAANIFERLVN

ARFGEF2

521

Q9Y6D5
LQDELENRSNQVRCA

CEP112

871

Q8N8E3
ECLQRFADSLQEVVN

ACAP3

76

Q96P50
NELNNGVSRVQEECR

BRWD3

736

Q6RI45
SEDARQQQLARRCFE

AOPEP

786

Q8N6M6
ILDNVNCVINRFQEE

FAM186B

41

Q8IYM0
SEERDNAIRVCFQIE

DCP2

26

Q8IU60
LERQGRCDESNFRQV

DEDD

71

O75618
NPDQRISQDVERFCR

ABCD4

141

O14678
EVSQRQAFQETRECI

ADCY5

401

O95622
REFDDLSPEQQRQAC

ATP2A3

656

Q93084
CQELSRVTRENCNEF

ADAMTS20

1006

P59510
EELNRELRQCNLQQF

RASSF7

281

Q02833
QAIENCDRSFRAILA

RBM45

176

Q8IUH3
CRFSREEFEQILQER

RILP

241

Q96NA2
CQVFARQRARDLSEQ

RIMBP3B

461

A6NNM3
CQVFARQRARDLSEQ

RIMBP3C

461

A6NJZ7
VRELEEQCRSQTEQF

TSPOAP1

501

O95153
QVRFKDICEAQNEQR

INSYN2A

46

Q6ZSG2
ALEERLAQCQDQSSR

OLFML3

36

Q9NRN5
QENIAGITFCNLDRE

DZIP1L

56

Q8IYY4
SKVFLEIDNRQCVQD

NOTCH2

1621

Q04721
CAATVRFNENLRDAV

FAR1

111

Q8WVX9
LENFCELQFRENAVR

KIAA0825

291

Q8IV33
NCTQRILEQRENTDF

EURL

156

Q9NYK6
LCQELQRDNVDLFVQ

MMS22L

686

Q6ZRQ5
RFQEILNCLFQNREE

KIF18A

421

Q8NI77
FVDDIDDRIFVCNRN

LRP1

296

Q07954
RQKQFNRDVLDCVVD

IQSEC1

581

Q6DN90
QQRQAARQEEENSIC

KCNJ5-AS1

106

Q8TAV5
EIFQRQVNLIFCDEV

FSIP2

5956

Q5CZC0
SQVEDQRECVSRQEY

IGF1R

871

P08069
FRSQCLQVPEREAQD

PDCD2L

96

Q9BRP1
EDNCDIFQNLSKRQR

PDE4A

516

P27815
EEQDRVLSFRCQARI

PECAM1

196

P16284
QTQNFDAEAVCRSIR

PDE8B

186

O95263
CALATFDRQELQRNV

GPS1

296

Q13098
EDCVNNIRFLDNRLF

DCAF10

211

Q5QP82
LDQCFQLRLFEQDAE

KALRN

306

O60229
ACDLRFRSIVQCVND

DDHD2

226

O94830
NFDEIDECVRNIERS

MYO10

946

Q9HD67
RTNQQDSDIEALARC

NEK11

516

Q8NG66
CQLNNRDRRNVDFTS

KNL1

1301

Q8NG31
FVTRNKDVFQCEVRN

SERPINE2

126

P07093
DRCRFFINDIEVASN

ELP1

626

O95163
LQQFNLDVRECEQFA

EXOC6B

696

Q9Y2D4
GEFIQEIRRQLEACQ

OAS1

96

P00973
CRVRNNTCFVDAVAE

PADI3

311

Q9ULW8
AQSCQQRLDREISNF

OSBPL1A

366

Q9BXW6
NINEARNILKTFEEC

PRPF39

436

Q86UA1
LDFDRAQRACLQNSA

ACAN

166

P16112
TENIRRVFNDCRDII

GNAL

356

P38405
RNVACTLDDAQFVLN

EFCAB5

1041

A4FU69
ICSFLQEQAQEDRRE

CSF1R

906

P07333
NRLQSCAEIDLFRAA

KLHL26

216

Q53HC5
EFLCEEFRNRNQRIV

CPN1

101

P15169
LNLNDAESRRQCNVD

DOCK11

786

Q5JSL3
FHRVEQCVRNINLEE

BRCA2

2416

P51587
NSVKERESERNQCNF

CENPF

1176

P49454
RNRCFLEENFTIQGD

CACNA1I

236

Q9P0X4
NNDETCEQRAARISL

C5

706

P01031
NCQFFIRDLEQEVLC

ITSN1

1646

Q15811
RFLQQELCAVQEEVS

JMJD4

341

Q9H9V9
SRDLEDRVCNQIEFL

IFIT3

31

O14879
AVDTENIRRVFNDCR

GNAS

366

P63092
CQLDNADEQAAQIRR

CADPS2

261

Q86UW7
RENQRQNECVSEISN

CEP192

931

Q8TEP8
RQAVRLEDNSETNAC

ERMARD

461

Q5T6L9
TLLRQRCTAFDAEQQ

DNAH9

1221

Q9NYC9
EDINTLRECVQILFN

GTF2IRD1

346

Q9UHL9
QVLDLRNVDENFCDI

PRAMEF8

101

Q5VWM4
QTCSVLDLNAFERQN

RYR1

3836

P21817
FRCAEENNQVDKRIT

SLC1A1

341

P43005
LDDFIQNDRAAECNI

DHX9

426

Q08211
QAFETCQAAERQRLL

PACSIN3

226

Q9UKS6
NLFRENDCIVRINDG

PARD3

316

Q8TEW0
DQAEFLCVVSRELNN

KCTD2

226

Q14681
QLEACQQERQFEVKF

OAS3

846

Q9Y6K5
IQCDVADQQQLRDTF

HPGD

61

P15428
QALTFRNRQAEDEAC

MIGA1

226

Q8NAN2
SNDVVCKNQDELRNR

FAN1

131

Q9Y2M0
QARDTLAQLQDCFRL

PLIN4

1206

Q96Q06
ECRQQDVAQFADFRE

SYNC

261

Q9H7C4
CITQNRQDLAERFDV

RFPL1

151

O75677
QAEECTLRANIEAFN

STRIP2

761

Q9ULQ0
AQRCQRLADAERLFQ

PLEKHG4

546

Q58EX7
CQVFARQRARDLSEQ

RIMBP3

461

Q9UFD9
DNALRTFAQNCRNIE

FBXL20

106

Q96IG2
DTENIRRVFNDCRDI

GNAS

1011

Q5JWF2
DQVFCARLLEEARNR

FGD1

396

P98174
LSNRCQVFDRFQDTV

PHF12

331

Q96QT6
DTELQLRRDAIFCQA

PREX1

1316

Q8TCU6
SRCQEERAELQAQLE

RUFY4

451

Q6ZNE9
AEECALRANIERFNA

STRIP1

766

Q5VSL9
ESNNIRQLDDFLEDC

KIAA0753

731

Q2KHM9
FVQVARNLFCLQLDE

STXBP4

256

Q6ZWJ1
RCQLSLQDLDDFVDQ

SOWAHB

386

A6NEL2
LDAQNQQRCEAARAE

URB1

971

O60287
QQRCEAARAEADLFL

URB1

976

O60287
LRDFSLQQINAVCDE

SKI

131

P12755
EQTLQRAEFLRNCEE

SPTBN5

636

Q9NRC6
QAEQQEQLFLRECGR

SPTBN5

2046

Q9NRC6
ENCESRAENFQELLR

SLX4

806

Q8IY92
GRLCRDFQDDLAQLQ

ANHX

26

E9PGG2
QVLDLRNVDENFCDI

PRAMEF7

101

Q5VXH5
ETCPRQVDNRLVENF

TMEM210

76

A6NLX4
RNSEFEIFVDCDINR

TPH1

56

P17752
LQQLNEQRRQDVFCD

ZBTB8A

11

Q96BR9
RSIFEAVAQNNCQDL

TRPV1

116

Q8NER1
TALSNEQQARRDCQE

TPR

1056

P12270
TAFERLQQELEQQRC

TRIM15

171

Q9C019
AEFCLFDRVVNVREN

XRN1

1101

Q8IZH2
TVDNVQRCQFLDDRI

TTC3

806

P53804
NRQDLAERFDVSVCI

RFPL2

216

O75678
EEERQRGQFLQQCCS

TTLL6

401

Q8N841
QLEQNEAAFSVAVCR

SF3B3

881

Q15393
LRKLVSFDQEDNCQV

PLCH1

1546

Q4KWH8
IVLKRCEDNQSRSND

TOPAZ1

1616

Q8N9V7
RQNRICGFLDIEENE

PLEKHA1

6

Q9HB21
EQRQFVTCILCQEEQ

UBR2

1101

Q8IWV8
TVEGCREELQNQANF

UBR4

1791

Q5T4S7
DQRRNNEELVVSASC

ZNF512

526

Q96ME7
ENCTQLRENAVERLD

TCTN2

496

Q96GX1
LDQCFQLRLFEQDAE

TRIO

336

O75962
LNEDRVKQLERTFNC

NLRP14

536

Q86W24
ERQLADAKQCVQFVE

PDE4DIP

366

Q5VU43