Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	peroxisome proliferator activated receptor binding	ASXL1 ASXL2	3.92e-04	21	28	2	GO:0042975
GeneOntologyMolecularFunction	metalloendopeptidase activity	ADAMTS17 ADAM19 ADAMTS4	6.21e-04	120	28	3	GO:0004222
GeneOntologyMolecularFunction	ubiquitin conjugating enzyme binding	RNF19A RNF144A	1.16e-03	36	28	2	GO:0031624
GeneOntologyMolecularFunction	ubiquitin-like protein conjugating enzyme binding	RNF19A RNF144A	1.58e-03	42	28	2	GO:0044390
GeneOntologyMolecularFunction	extracellular matrix structural constituent	FBN2 HMCN1 FBN3	2.26e-03	188	28	3	GO:0005201
GeneOntologyMolecularFunction	metallopeptidase activity	ADAMTS17 ADAM19 ADAMTS4	2.70e-03	200	28	3	GO:0008237
GeneOntologyMolecularFunction	endopeptidase activity	ADAMTS17 HGF ADAM19 ADAMTS4	2.88e-03	430	28	4	GO:0004175
GeneOntologyMolecularFunction	calcium ion binding	SCUBE3 SCUBE1 FBN2 HMCN1 FBN3	3.51e-03	749	28	5	GO:0005509
GeneOntologyCellularComponent	PR-DUB complex	ASXL1 ASXL2	1.11e-05	4	29	2	GO:0035517
GeneOntologyCellularComponent	extracellular matrix	ADAMTS17 LAMB4 ADAM19 FBN2 HMCN1 ADAMTS4 FBN3	2.48e-05	656	29	7	GO:0031012
GeneOntologyCellularComponent	external encapsulating structure	ADAMTS17 LAMB4 ADAM19 FBN2 HMCN1 ADAMTS4 FBN3	2.53e-05	658	29	7	GO:0030312
GeneOntologyCellularComponent	collagen-containing extracellular matrix	ADAMTS17 LAMB4 ADAM19 FBN2 HMCN1 ADAMTS4	7.46e-05	530	29	6	GO:0062023
GeneOntologyCellularComponent	microfibril	FBN2 FBN3	1.44e-04	13	29	2	GO:0001527
GeneOntologyCellularComponent	PcG protein complex	ASXL1 ASXL2	2.36e-03	52	29	2	GO:0031519
Domain	cEGF	SCUBE3 SCUBE1 FBN2 HMCN1 FBN3	3.34e-10	26	28	5	IPR026823
Domain	cEGF	SCUBE3 SCUBE1 FBN2 HMCN1 FBN3	3.34e-10	26	28	5	PF12662
Domain	EGF_1	SCUBE3 LAMB4 SCUBE1 ADAM19 FBN2 HMCN1 FBN3 TMEFF2	2.66e-09	255	28	8	PS00022
Domain	EGF-like_CS	SCUBE3 LAMB4 SCUBE1 ADAM19 FBN2 HMCN1 FBN3 TMEFF2	3.19e-09	261	28	8	IPR013032
Domain	EGF_2	SCUBE3 LAMB4 SCUBE1 ADAM19 FBN2 HMCN1 FBN3 TMEFF2	3.59e-09	265	28	8	PS01186
Domain	EGF_3	SCUBE3 SCUBE1 ADAM19 FBN2 HMCN1 FBN3 TMEFF2	4.32e-08	235	28	7	PS50026
Domain	EGF-like_dom	SCUBE3 SCUBE1 ADAM19 FBN2 HMCN1 FBN3 TMEFF2	6.42e-08	249	28	7	IPR000742
Domain	Growth_fac_rcpt_	SCUBE3 SCUBE1 FBN2 HMCN1 EGFR FBN3	9.98e-08	156	28	6	IPR009030
Domain	EGF_CA	SCUBE3 SCUBE1 FBN2 HMCN1 FBN3	1.66e-07	86	28	5	PF07645
Domain	EGF_Ca-bd_CS	SCUBE3 SCUBE1 FBN2 HMCN1 FBN3	3.04e-07	97	28	5	IPR018097
Domain	EGF_CA	SCUBE3 SCUBE1 FBN2 HMCN1 FBN3	3.37e-07	99	28	5	PS01187
Domain	ASX_HYDROXYL	SCUBE3 SCUBE1 FBN2 HMCN1 FBN3	3.55e-07	100	28	5	PS00010
Domain	EGF-type_Asp/Asn_hydroxyl_site	SCUBE3 SCUBE1 FBN2 HMCN1 FBN3	4.74e-07	106	28	5	IPR000152
Domain	EGF_CA	SCUBE3 SCUBE1 FBN2 HMCN1 FBN3	9.54e-07	122	28	5	SM00179
Domain	EGF-like_Ca-bd_dom	SCUBE3 SCUBE1 FBN2 HMCN1 FBN3	1.03e-06	124	28	5	IPR001881
Domain	EGF	SCUBE3 SCUBE1 FBN2 HMCN1 FBN3 TMEFF2	1.11e-06	235	28	6	SM00181
Domain	HARE-HTH	ASXL1 ASXL2	6.50e-06	3	28	2	PF05066
Domain	ASXH	ASXL1 ASXL2	6.50e-06	3	28	2	PF13919
Domain	PHD_3	ASXL1 ASXL2	6.50e-06	3	28	2	PF13922
Domain	HB1/Asxl_HTH	ASXL1 ASXL2	6.50e-06	3	28	2	IPR007759
Domain	ASX-like_PHD	ASXL1 ASXL2	6.50e-06	3	28	2	IPR026905
Domain	ASX/ASX-like	ASXL1 ASXL2	6.50e-06	3	28	2	IPR024811
Domain	FBN	FBN2 FBN3	6.50e-06	3	28	2	IPR011398
Domain	ASXH	ASXL1 ASXL2	6.50e-06	3	28	2	IPR028020
Domain	ADAM_Cys-rich	ADAMTS17 ADAM19 ADAMTS4	8.62e-06	27	28	3	IPR006586
Domain	ACR	ADAMTS17 ADAM19 ADAMTS4	8.62e-06	27	28	3	SM00608
Domain	Peptidase_M12B_N	ADAMTS17 ADAM19 ADAMTS4	2.66e-05	39	28	3	IPR002870
Domain	Pep_M12B_propep	ADAMTS17 ADAM19 ADAMTS4	2.66e-05	39	28	3	PF01562
Domain	DISINTEGRIN_1	ADAMTS17 ADAM19 ADAMTS4	2.87e-05	40	28	3	PS00427
Domain	ADAM_MEPRO	ADAMTS17 ADAM19 ADAMTS4	2.87e-05	40	28	3	PS50215
Domain	DISINTEGRIN_2	ADAMTS17 ADAM19 ADAMTS4	2.87e-05	40	28	3	PS50214
Domain	Reprolysin	ADAMTS17 ADAM19 ADAMTS4	2.87e-05	40	28	3	PF01421
Domain	Peptidase_M12B	ADAMTS17 ADAM19 ADAMTS4	2.87e-05	40	28	3	IPR001590
Domain	Disintegrin_dom	ADAMTS17 ADAM19 ADAMTS4	3.10e-05	41	28	3	IPR001762
Domain	EGF	SCUBE3 HMCN1 FBN3 TMEFF2	3.57e-05	126	28	4	PF00008
Domain	TB	FBN2 FBN3	4.53e-05	7	28	2	PF00683
Domain	-	FBN2 FBN3	6.03e-05	8	28	2	3.90.290.10
Domain	TB	FBN2 FBN3	7.75e-05	9	28	2	PS51364
Domain	TB_dom	FBN2 FBN3	7.75e-05	9	28	2	IPR017878
Domain	E3_UB_ligase_RBR	RNF19A RNF144A	9.68e-05	10	28	2	IPR031127
Domain	TSP_1	ADAMTS17 HMCN1 ADAMTS4	1.13e-04	63	28	3	PF00090
Domain	Ephrin_rec_like	SCUBE3 SCUBE1	1.18e-04	11	28	2	PF07699
Domain	TSP1	ADAMTS17 HMCN1 ADAMTS4	1.24e-04	65	28	3	SM00209
Domain	TSP1_rpt	ADAMTS17 HMCN1 ADAMTS4	1.24e-04	65	28	3	IPR000884
Domain	TSP1	ADAMTS17 HMCN1 ADAMTS4	1.24e-04	65	28	3	PS50092
Domain	EGF_3	SCUBE3 SCUBE1	1.42e-04	12	28	2	PF12947
Domain	EGF_dom	SCUBE3 SCUBE1	1.42e-04	12	28	2	IPR024731
Domain	IBR	RNF19A RNF144A	1.95e-04	14	28	2	PF01485
Domain	IBR	RNF19A RNF144A	1.95e-04	14	28	2	SM00647
Domain	IBR_dom	RNF19A RNF144A	2.25e-04	15	28	2	IPR002867
Domain	MetalloPept_cat_dom	ADAMTS17 ADAM19 ADAMTS4	2.38e-04	81	28	3	IPR024079
Domain	-	ADAMTS17 ADAM19 ADAMTS4	2.38e-04	81	28	3	3.40.390.10
Domain	ZINC_PROTEASE	ADAMTS17 ADAM19 ADAMTS4	4.17e-04	98	28	3	PS00142
Domain	Kazal_1	TMEFF2 SPINK5	4.91e-04	22	28	2	PF00050
Domain	ADAM_spacer1	ADAMTS17 ADAMTS4	5.38e-04	23	28	2	IPR010294
Domain	ADAM_spacer1	ADAMTS17 ADAMTS4	5.38e-04	23	28	2	PF05986
Domain	Peptidase_M12B_ADAM-TS	ADAMTS17 ADAMTS4	5.86e-04	24	28	2	IPR013273
Domain	Ephrin_rec_like	SCUBE3 SCUBE1	6.36e-04	25	28	2	SM01411
Domain	Tyr-kin_ephrin_A/B_rcpt-like	SCUBE3 SCUBE1	6.36e-04	25	28	2	IPR011641
Domain	hEGF	FBN2 FBN3	8.00e-04	28	28	2	PF12661
Domain	Kazal_2	TMEFF2 SPINK5	1.32e-03	36	28	2	PF07648
Domain	CYSTEINE_SWITCH	ADAMTS17 ADAM19	1.71e-03	41	28	2	PS00546
Domain	Pept_M10_metallopeptidase	ADAMTS17 ADAM19	1.88e-03	43	28	2	IPR001818
Domain	KAZAL	TMEFF2 SPINK5	2.15e-03	46	28	2	SM00280
Domain	CUB	SCUBE3 SCUBE1	2.44e-03	49	28	2	PF00431
Domain	KAZAL_2	TMEFF2 SPINK5	2.54e-03	50	28	2	PS51465
Domain	CUB	SCUBE3 SCUBE1	2.54e-03	50	28	2	SM00042
Domain	Kazal_dom	TMEFF2 SPINK5	2.64e-03	51	28	2	IPR002350
Domain	-	SCUBE3 SCUBE1	2.74e-03	52	28	2	2.60.120.290
Domain	CUB	SCUBE3 SCUBE1	2.85e-03	53	28	2	PS01180
Domain	CUB_dom	SCUBE3 SCUBE1	3.29e-03	57	28	2	IPR000859
Pathway	REACTOME_DEGRADATION_OF_THE_EXTRACELLULAR_MATRIX	SCUBE3 SCUBE1 FBN2 ADAMTS4 FBN3	6.09e-06	140	27	5	M587
Pathway	REACTOME_EXTRACELLULAR_MATRIX_ORGANIZATION	SCUBE3 SCUBE1 ADAM19 FBN2 ADAMTS4 FBN3	1.79e-05	300	27	6	M610
Pathway	REACTOME_DEGRADATION_OF_THE_EXTRACELLULAR_MATRIX	SCUBE3 SCUBE1 FBN2 ADAMTS4	6.17e-05	114	27	4	MM14571
Pathway	REACTOME_EXTRACELLULAR_MATRIX_ORGANIZATION	SCUBE3 SCUBE1 ADAM19 FBN2 ADAMTS4	1.15e-04	258	27	5	MM14572
Pathway	REACTOME_MET_RECEPTOR_RECYCLING	HGF GGA3	1.57e-04	10	27	2	M27777
Pathway	REACTOME_MET_RECEPTOR_RECYCLING	HGF GGA3	1.57e-04	10	27	2	MM15516
Pubmed	ASXL1/2 mutations and myeloid malignancies.	ASXL1 ASXL2	6.71e-07	2	29	2	36068610
Pubmed	HGF induces novel EGFR functions involved in resistance formation to tyrosine kinase inhibitors.	HGF EGFR	6.71e-07	2	29	2	23045285
Pubmed	Synchronous alterations of Wnt and epidermal growth factor receptor signaling pathways through aberrant methylation and mutation in non small cell lung cancer.	EGFR WNT1	6.71e-07	2	29	2	17947472
Pubmed	A novel secreted, cell-surface glycoprotein containing multiple epidermal growth factor-like repeats and one CUB domain is highly expressed in primary osteoblasts and bones.	SCUBE3 SCUBE1	6.71e-07	2	29	2	15234972
Pubmed	Transcription-dependent epidermal growth factor receptor activation by hepatocyte growth factor.	HGF EGFR	6.71e-07	2	29	2	18234969
Pubmed	ASXL2 is essential for haematopoiesis and acts as a haploinsufficient tumour suppressor in leukemia.	ASXL1 ASXL2	6.71e-07	2	29	2	28516957
Pubmed	Can signal peptide-CUB-EGF domain-containing protein (SCUBE) levels be a marker of angiogenesis in patients with psoriasis?	SCUBE3 SCUBE1	6.71e-07	2	29	2	28238185
Pubmed	Ligand-triggered resistance to molecular targeted drugs in lung cancer: roles of hepatocyte growth factor and epidermal growth factor receptor ligands.	HGF EGFR	6.71e-07	2	29	2	22435662
Pubmed	Hepatocyte growth factor inhibits lipopolysaccharide-induced oxidative stress via epithelial growth factor receptor degradation.	HGF EGFR	6.71e-07	2	29	2	22936342
Pubmed	Electrical stimulation accelerates neuromuscular junction formation through ADAM19/neuregulin/ErbB signaling in vitro.	ADAM19 EGFR	2.01e-06	3	29	2	23603262
Pubmed	Detection of serum protein and circulating mRNA of cMET, HGF EGF and EGFR levels in lung cancer patients to guide individualized therapy.	HGF EGFR	2.01e-06	3	29	2	31104010
Pubmed	Regulation of HGF expression by ΔEGFR-mediated c-Met activation in glioblastoma cells.	HGF EGFR	2.01e-06	3	29	2	23359207
Pubmed	Additional sex comb-like (ASXL) proteins 1 and 2 play opposite roles in adipogenesis via reciprocal regulation of peroxisome proliferator-activated receptor {gamma}.	ASXL1 ASXL2	2.01e-06	3	29	2	21047783
Pubmed	HGF-independent potentiation of EGFR action by c-Met.	HGF EGFR	2.01e-06	3	29	2	21423210
Pubmed	The relationship of serum SCUBE-1, -2 and -3 levels with clinical findings and ultrasonographic skin thickness in systemic sclerosis patients.	SCUBE3 SCUBE1	2.01e-06	3	29	2	31991528
Pubmed	Identification of a novel family of cell-surface proteins expressed in human vascular endothelium.	SCUBE3 SCUBE1	2.01e-06	3	29	2	12270931
Pubmed	Characterization of Asxl1, a murine homolog of Additional sex combs, and analysis of the Asx-like gene family.	ASXL1 ASXL2	2.01e-06	3	29	2	16412590
Pubmed	Functional proteomics of the epigenetic regulators ASXL1, ASXL2 and ASXL3: a convergence of proteomics and epigenetics for translational medicine.	ASXL1 ASXL2	2.01e-06	3	29	2	25835095
Pubmed	ASXL2 mutations are frequently found in pediatric AML patients with t(8;21)/ RUNX1-RUNX1T1 and associated with a better prognosis.	ASXL1 ASXL2	2.01e-06	3	29	2	28063196
Pubmed	Familial and Somatic BAP1 Mutations Inactivate ASXL1/2-Mediated Allosteric Regulation of BAP1 Deubiquitinase by Targeting Multiple Independent Domains.	ASXL1 ASXL2	2.01e-06	3	29	2	29284740
Pubmed	Kinetic Characterization of ASXL1/2-Mediated Allosteric Regulation of the BAP1 Deubiquitinase.	ASXL1 ASXL2	2.01e-06	3	29	2	33731362
Pubmed	Understanding the phenotypic spectrum of ASXL-related disease: Ten cases and a review of the literature.	ASXL1 ASXL2	2.01e-06	3	29	2	33751773
Pubmed	RNF144A sustains EGFR signaling to promote EGF-dependent cell proliferation.	EGFR RNF144A	4.02e-06	4	29	2	30171075
Pubmed	Heparin/heparan sulfate controls fibrillin-1, -2 and -3 self-interactions in microfibril assembly.	FBN2 FBN3	4.02e-06	4	29	2	25034023
Pubmed	BAP1/ASXL complex modulation regulates epithelial-mesenchymal transition during trophoblast differentiation and invasion.	ASXL1 ASXL2	4.02e-06	4	29	2	34170818
Pubmed	MET, HGF, EGFR, and PXN gene copy number in lung cancer using DNA extracts from FFPE archival samples and prognostic significance.	HGF EGFR	4.02e-06	4	29	2	19817696
Pubmed	Immunohistochemical detection of EGFR, fibrillin-2, P-cadherin and AP2beta as biomarkers for rhabdomyosarcoma diagnostics.	FBN2 EGFR	4.02e-06	4	29	2	19469909
Pubmed	Correlation of clinicopathological parameters with HGF, c-Met, EGFR, and IGF-1R expression in uveal melanoma.	HGF EGFR	4.02e-06	4	29	2	20061986
Pubmed	Oncogenic Truncations of ASXL1 Enhance a Motif for BRD4 ET-Domain Binding.	ASXL1 ASXL2	4.02e-06	4	29	2	34536441
Pubmed	Comprehensive molecular analyses of lung adenocarcinoma with regard to the epidermal growth factor receptor, K-ras, MET, and hepatocyte growth factor status.	HGF EGFR	4.02e-06	4	29	2	20150826
Pubmed	Integrin α6β4 Promotes Autocrine Epidermal Growth Factor Receptor (EGFR) Signaling to Stimulate Migration and Invasion toward Hepatocyte Growth Factor (HGF).	HGF EGFR	4.02e-06	4	29	2	26381405
Pubmed	Scube3 is expressed in multiple tissues during development but is dispensable for embryonic survival in the mouse.	SCUBE3 SCUBE1	6.70e-06	5	29	2	23383134
Pubmed	Negative action of hepatocyte growth factor/c-Met system on angiotensin II signaling via ligand-dependent epithelial growth factor receptor degradation mechanism in vascular smooth muscle cells.	HGF EGFR	6.70e-06	5	29	2	19713535
Pubmed	GGA2 interacts with EGFR cytoplasmic domain to stabilize the receptor expression and promote cell growth.	EGFR GGA3	6.70e-06	5	29	2	29358589
Pubmed	Methylation of CLDN6, FBN2, RBP1, RBP4, TFPI2, and TMEFF2 in esophageal squamous cell carcinoma.	FBN2 TMEFF2	1.00e-05	6	29	2	19288010
Pubmed	MEK, p38, and PI-3K mediate cross talk between EGFR and TNFR in enhancing hepatocyte growth factor production from human mesenchymal stem cells.	HGF EGFR	1.00e-05	6	29	2	19692652
Pubmed	Disruption of Scube2 Impairs Endochondral Bone Formation.	SCUBE3 SCUBE1	1.41e-05	7	29	2	25639508
Pubmed	A family of structurally related RING finger proteins interacts specifically with the ubiquitin-conjugating enzyme UbcM4.	RNF19A RNF144A	1.87e-05	8	29	2	10431818
Pubmed	Adamts17 is involved in skeletogenesis through modulation of BMP-Smad1/5/8 pathway.	ADAMTS17 FBN2	1.87e-05	8	29	2	31201465
Pubmed	The BAP1/ASXL2 Histone H2A Deubiquitinase Complex Regulates Cell Proliferation and Is Disrupted in Cancer.	ASXL1 ASXL2	2.41e-05	9	29	2	26416890
Pubmed	Additional sex combs-like family genes are required for normal cardiovascular development.	ASXL1 ASXL2	2.41e-05	9	29	2	24860998
Pubmed	ASXL3 bridges BRD4 to BAP1 complex and governs enhancer activity in small cell lung cancer.	ASXL1 ASXL2	3.01e-05	10	29	2	32669118
Pubmed	MUC20 suppresses the hepatocyte growth factor-induced Grb2-Ras pathway by binding to a multifunctional docking site of met.	HGF EGFR	3.01e-05	10	29	2	15314156
Pubmed	The deubiquitinating enzyme BAP1 regulates cell growth via interaction with HCF-1.	ASXL1 ASXL2	3.01e-05	10	29	2	19815555
Pubmed	O-fucosylation of thrombospondin type 1 repeats restricts epithelial to mesenchymal transition (EMT) and maintains epiblast pluripotency during mouse gastrulation.	ADAMTS17 HMCN1 ADAMTS4	3.38e-05	75	29	3	20637190
Pubmed	Insights on ADAMTS proteases and ADAMTS-like proteins from mammalian genetics.	ADAMTS17 ADAMTS4	4.41e-05	12	29	2	25770910
Pubmed	Loss of the tumor suppressor BAP1 causes myeloid transformation.	ASXL1 ASXL2	5.21e-05	13	29	2	22878500
Pubmed	The role of height-associated loci identified in genome wide association studies in the determination of pediatric stature.	ADAMTS17 ZNF462 SCUBE3	6.03e-05	91	29	3	20546612
Pubmed	Identification of host proteins required for HIV infection through a functional genomic screen.	ASXL2 NUP155 EGFR WNT1	7.45e-05	272	29	4	18187620
Pubmed	The ubiquitin carboxyl hydrolase BAP1 forms a ternary complex with YY1 and HCF-1 and is a critical regulator of gene expression.	ASXL1 ASXL2	8.00e-05	16	29	2	20805357
Pubmed	Fibulin-1 is required during cardiac ventricular morphogenesis for versican cleavage, suppression of ErbB2 and Erk1/2 activation, and to attenuate trabecular cardiomyocyte proliferation.	ADAMTS4 EGFR	9.06e-05	17	29	2	22183742
Pubmed	Proteolysis of fibrillin-2 microfibrils is essential for normal skeletal development.	ADAMTS17 FBN2	1.02e-04	18	29	2	35503090
Pubmed	SCUBE3 loss-of-function causes a recognizable recessive developmental disorder due to defective bone morphogenetic protein signaling.	SCUBE3 SCUBE1	1.02e-04	18	29	2	33308444
Pubmed	Functional proteomics mapping of a human signaling pathway.	PPP1R10 ASXL2 FBN2 NUP155 GGA3	1.18e-04	591	29	5	15231748
Pubmed	Resetting the epigenetic balance of Polycomb and COMPASS function at enhancers for cancer therapy.	ASXL1 ASXL2	1.26e-04	20	29	2	29785026
Pubmed	Defining the human deubiquitinating enzyme interaction landscape.	ASXL1 LAMB4 ASXL2 NUP155 RBM45 NPLOC4	1.54e-04	1005	29	6	19615732
Pubmed	Large-scale phage-based screening reveals extensive pan-viral mimicry of host short linear motifs.	EGFR GGA3	1.83e-04	24	29	2	37100772
Pubmed	Many sequence variants affecting diversity of adult human height.	ADAMTS17 ZNF462 SCUBE3	2.30e-04	143	29	3	18391951
Pubmed	Deletion of Pdcd5 in mice led to the deficiency of placenta development and embryonic lethality.	HGF EGFR	2.33e-04	27	29	2	28542142
Pubmed	Pro-prion, as a membrane adaptor protein for E3 ligase c-Cbl, facilitates the ubiquitination of IGF-1R, promoting melanoma metastasis.	PPP1R10 HIGD2B ASXL2 EGFR NPLOC4	2.41e-04	689	29	5	36543142
Pubmed	The matrisome: in silico definition and in vivo characterization by proteomics of normal and tumor extracellular matrices.	ADAMTS17 ADAM19 HMCN1	3.62e-04	167	29	3	22159717
Pubmed	APC haploinsufficiency coupled with p53 loss sufficiently induces mucinous cystic neoplasms and invasive pancreatic carcinoma in mice.	EGFR WNT1	3.70e-04	34	29	2	26411367
Pubmed	β-Catenin gain of function in muscles impairs neuromuscular junction formation.	HGF WNT1	3.70e-04	34	29	2	22627288
Pubmed	Foxf2 in intestinal fibroblasts reduces numbers of Lgr5(+) stem cells and adenoma formation by inhibiting Wnt signaling.	HGF WNT1	3.93e-04	35	29	2	23376422
Pubmed	Tracing the origin of hair follicle stem cells.	ADAMTS17 FBN2	3.93e-04	35	29	2	34108685
Pubmed	Galnt1 is required for normal heart valve development and cardiac function.	ADAMTS4 EGFR	4.16e-04	36	29	2	25615642
Pubmed	O-fucosylation of thrombospondin type 1 repeats is essential for ECM remodeling and signaling during bone development.	ADAMTS17 FBN2	4.16e-04	36	29	2	35167946
Pubmed	Genetic determinants of height growth assessed longitudinally from infancy to adulthood in the northern Finland birth cohort 1966.	ADAMTS17 ZNF462	4.39e-04	37	29	2	19266077
Pubmed	Hypertonicity-responsive ubiquitin ligase RNF183 promotes Na, K-ATPase lysosomal degradation through ubiquitination of its β1 subunit.	PPP1R10 NUP155 NPLOC4 GGA3	5.04e-04	449	29	4	31732153
Pubmed	Hundreds of variants clustered in genomic loci and biological pathways affect human height.	ADAMTS17 ZNF462 PTPDC1	5.95e-04	198	29	3	20881960
Pubmed	FBXO32 links ubiquitination to epigenetic reprograming of melanoma cells.	UTP20 NUP155 NPLOC4	7.26e-04	212	29	3	33462405
Pubmed	Comparative proteomic analysis of supportive and unsupportive extracellular matrix substrates for human embryonic stem cell maintenance.	FBN2 ADAMTS4	8.02e-04	50	29	2	23658023
Interaction	HSPA14 interactions	ASXL1 ASXL2 ADAM19 EGFR	9.24e-06	93	29	4	int:HSPA14
Interaction	DPH6 interactions	ADAMTS4 EGFR DPH6	1.17e-05	31	29	3	int:DPH6
Interaction	DKK1 interactions	EGFR RBM45 WNT1	1.29e-05	32	29	3	int:DKK1
Interaction	SCUBE1 interactions	SCUBE3 SCUBE1	1.99e-05	5	29	2	int:SCUBE1
Interaction	SCUBE3 interactions	SCUBE3 SCUBE1	5.57e-05	8	29	2	int:SCUBE3
Cytoband	6p21.3	SCUBE3 PPP1R10	1.09e-02	250	29	2	6p21.3
Cytoband	Ensembl 112 genes in cytogenetic band chr17q25	NPLOC4 GGA3	1.61e-02	307	29	2	chr17q25
GeneFamily	ADAM metallopeptidases with thrombospondin type 1 motif	ADAMTS17 ADAMTS4	1.58e-04	19	18	2	50
GeneFamily	Ring finger proteins	RNF19A RNF144A	3.00e-02	275	18	2	58
Coexpression	NABA_MATRISOME	ADAMTS17 SCUBE3 HGF LAMB4 SCUBE1 ADAM19 FBN2 HMCN1 ADAMTS4 WNT1 FBN3	5.67e-09	1026	29	11	M5889
Coexpression	NABA_MATRISOME	ADAMTS17 SCUBE3 HGF SCUBE1 ADAM19 FBN2 HMCN1 ADAMTS4 WNT1	8.88e-07	1008	29	9	MM17056
Coexpression	HE_LIM_SUN_FETAL_LUNG_C0_MESENCHYMAL_3_CELL	SCUBE3 HGF FBN2 FBN3 TMEFF2	1.27e-06	174	29	5	M45676
Coexpression	HE_LIM_SUN_FETAL_LUNG_C3_VENOUS_ENDOTHELIAL_CELL	SCUBE3 XAF1 HMCN1 SPINK5	2.30e-06	85	29	4	M45761
Coexpression	NABA_MATRISOME_ASSOCIATED	ADAMTS17 SCUBE3 HGF SCUBE1 ADAM19 ADAMTS4 WNT1	1.24e-05	738	29	7	MM17058
Coexpression	NABA_MATRISOME_ASSOCIATED	ADAMTS17 SCUBE3 HGF SCUBE1 ADAM19 ADAMTS4 WNT1	1.39e-05	751	29	7	M5885
Coexpression	NABA_ECM_GLYCOPROTEINS	LAMB4 FBN2 HMCN1 FBN3	6.22e-05	196	29	4	M3008
Coexpression	BREUHAHN_GROWTH_FACTOR_SIGNALING_IN_LIVER_CANCER	HGF EGFR	1.23e-04	15	29	2	M18219
Coexpression	BENPORATH_EED_TARGETS	SCUBE3 PPP1R10 ASXL1 FBN2 EGFR WNT1 TMEFF2	1.23e-04	1059	29	7	M7617
CoexpressionAtlas	dev gonad_e13.5_M_InterstitFLeydig_MafB_top-relative-expression-ranked_1000	ADAMTS17 HGF SCUBE1 ADAM19 FBN2 HMCN1 EGFR RNF19A RNF144A TMEFF2	4.12e-08	773	29	10	gudmap_dev gonad_e13.5_M_InterstitFLeydig_MafB_1000
CoexpressionAtlas	dev gonad_e12.5_M_InterstitLeydig_MafB_top-relative-expression-ranked_1000	HGF SCUBE1 ADAM19 FBN2 HMCN1 EGFR RNF19A RNF144A TMEFF2	5.28e-07	768	29	9	gudmap_dev gonad_e12.5_M_InterstitLeydig_MafB_1000
CoexpressionAtlas	dev gonad_e12.5_M_InterstitLeydig_MafB_k-means-cluster#1_top-relative-expression-ranked_1000	HGF FBN2 HMCN1 EGFR RNF144A TMEFF2	3.30e-06	310	29	6	gudmap_dev gonad_e12.5_M_InterstitLeydig_MafB_k1_1000
CoexpressionAtlas	dev gonad_e11.5_M_GonMes_Sma_k-means-cluster#3_top-relative-expression-ranked_1000	HGF SCUBE1 HMCN1 EGFR RNF19A TMEFF2	3.36e-06	311	29	6	gudmap_dev gonad_e11.5_M_GonMes_Sma_k3_1000
CoexpressionAtlas	dev gonad_e13.5_M_InterstitFLeydig_MafB_top-relative-expression-ranked_500	HGF SCUBE1 FBN2 HMCN1 EGFR TMEFF2	7.30e-06	356	29	6	gudmap_dev gonad_e13.5_M_InterstitFLeydig_MafB_500
CoexpressionAtlas	dev gonad_e12.5_M_InterstitTestis_Sma_top-relative-expression-ranked_1000	HGF SCUBE1 ADAM19 HMCN1 EGFR RNF19A RNF144A TMEFF2	7.80e-06	793	29	8	gudmap_dev gonad_e12.5_M_InterstitTestis_Sma_1000
CoexpressionAtlas	dev gonad_e11.5_M_GonadVasMes_Flk_k-means-cluster#4_top-relative-expression-ranked_500	HGF SCUBE1 FBN2 HMCN1 TMEFF2	8.23e-06	207	29	5	gudmap_dev gonad_e11.5_M_GonadVasMes_Flk_k4_500
CoexpressionAtlas	dev gonad_e12.5_M_InterstitLeydig_MafB_top-relative-expression-ranked_500	HGF SCUBE1 HMCN1 EGFR RNF19A TMEFF2	8.29e-06	364	29	6	gudmap_dev gonad_e12.5_M_InterstitLeydig_MafB_500
CoexpressionAtlas	dev gonad_e11.5_M_GonadVasMes_Flk_top-relative-expression-ranked_1000	ZNF462 HGF SCUBE1 ADAM19 FBN2 HMCN1 RNF19A TMEFF2	1.06e-05	827	29	8	gudmap_dev gonad_e11.5_M_GonadVasMes_Flk_1000
CoexpressionAtlas	DevelopingKidney_e13.5_podocyte cells_emap-27773_top-relative-expression-ranked_1000	SCUBE3 PTPDC1 ADAM19 NUP155 ADAMTS4 EGFR RBM45 TMEFF2	1.35e-05	855	29	8	gudmap_developingKidney_e13.5_podocyte cells_1000
CoexpressionAtlas	dev gonad_e11.5_M_GonadVasMes_Flk_top-relative-expression-ranked_500	HGF SCUBE1 ADAM19 FBN2 HMCN1 TMEFF2	1.82e-05	418	29	6	gudmap_dev gonad_e11.5_M_GonadVasMes_Flk_500
CoexpressionAtlas	dev gonad_e13.5_F_VascAssocMesenchStromOvary_MafB_k-means-cluster#3_top-relative-expression-ranked_500	SCUBE1 FBN2 HMCN1 EGFR	2.20e-05	122	29	4	gudmap_dev gonad_e13.5_F_VascAssocMesenchStromOvary_MafB_k3_500
CoexpressionAtlas	dev gonad_e11.5_M_GonMes_Sma_k-means-cluster#1_top-relative-expression-ranked_500	HGF SCUBE1 RNF19A TMEFF2	2.43e-05	125	29	4	gudmap_dev gonad_e11.5_M_GonMes_Sma_k1_500
CoexpressionAtlas	dev gonad_e13.5_M_InterstitTestis_Sma_top-relative-expression-ranked_200	HGF SCUBE1 HMCN1 EGFR	4.58e-05	147	29	4	gudmap_dev gonad_e13.5_M_InterstitTestis_Sma_200
CoexpressionAtlas	dev gonad_e12.5_F_VasAssocMesStromOvary_Sma_k-means-cluster#2_top-relative-expression-ranked_500	HGF HMCN1 EGFR	5.42e-05	54	29	3	gudmap_dev gonad_e12.5_F_VasAssocMesStromOvary_Sma_k2_500
CoexpressionAtlas	dev gonad_e13.5_M_InterstitTestis_Sma_top-relative-expression-ranked_1000	HGF SCUBE1 ADAM19 FBN2 HMCN1 EGFR TMEFF2	6.59e-05	777	29	7	gudmap_dev gonad_e13.5_M_InterstitTestis_Sma_1000
CoexpressionAtlas	dev gonad_e11.5_F_GonMes_Sma_k-means-cluster#4_top-relative-expression-ranked_500	SCUBE1 RNF19A TMEFF2	6.72e-05	58	29	3	gudmap_dev gonad_e11.5_F_GonMes_Sma_k4_500
CoexpressionAtlas	dev gonad_e12.5_M_InterstitLeydig_MafB_k-means-cluster#2_top-relative-expression-ranked_500	HGF HMCN1 EGFR TMEFF2	7.17e-05	165	29	4	gudmap_dev gonad_e12.5_M_InterstitLeydig_MafB_k2_500
CoexpressionAtlas	ratio_EmbryoidBody_vs_StemCell_top-relative-expression-ranked_2500_k-means-cluster#3	SCUBE3 HGF SCUBE1 ADAM19 FBN2 HMCN1 WNT1 TMEFF2	7.87e-05	1094	29	8	ratio_EB_vs_SC_2500_K3
CoexpressionAtlas	dev gonad_e13.5_M_InterstitFLeydig_MafB_k-means-cluster#3_top-relative-expression-ranked_1000	HGF HMCN1 EGFR RNF144A TMEFF2	8.37e-05	336	29	5	gudmap_dev gonad_e13.5_M_InterstitFLeydig_MafB_k3_1000
CoexpressionAtlas	dev gonad_e11.5_M_GonadVasMes_Flk_k-means-cluster#1_top-relative-expression-ranked_1000	HGF SCUBE1 FBN2 HMCN1 TMEFF2	8.49e-05	337	29	5	gudmap_dev gonad_e11.5_M_GonadVasMes_Flk_k1_1000
CoexpressionAtlas	Ectoderm Differentiated Cells_vs_Pluripotent Stem Cells-Confounder_removed-fold2.0_adjp0.05	SCUBE3 ASXL1 SCUBE1 ADAM19 FBN2 RNF19A WNT1 FBN3 RNF144A	9.82e-05	1466	29	9	PCBC_ratio_ECTO_vs_SC_cfr-2X-p05
CoexpressionAtlas	dev gonad_e13.5_F_VascAssocMesenchStromOvary_MafB_top-relative-expression-ranked_500	ADAMTS17 SCUBE1 FBN2 HMCN1 EGFR	1.11e-04	357	29	5	gudmap_dev gonad_e13.5_F_VascAssocMesenchStromOvary_MafB_500
CoexpressionAtlas	dev gonad_e13.5_M_InterstitTestis_Sma_top-relative-expression-ranked_500	HGF SCUBE1 HMCN1 EGFR TMEFF2	1.17e-04	361	29	5	gudmap_dev gonad_e13.5_M_InterstitTestis_Sma_500
CoexpressionAtlas	DevelopingKidney_e14.5 whole kidney - Wnt4 KO_emap-6674_k-means-cluster#3_top-relative-expression-ranked_500	PTPDC1 FBN2 HMCN1 EGFR	1.19e-04	188	29	4	gudmap_developingKidney_e14.5 whole kidney - Wnt4 KO_500_k3
CoexpressionAtlas	dev gonad_e12.5_M_InterstitTestis_Sma_k-means-cluster#4_top-relative-expression-ranked_1000	HGF HMCN1 EGFR RNF144A	1.26e-04	191	29	4	gudmap_dev gonad_e12.5_M_InterstitTestis_Sma_k4_1000
CoexpressionAtlas	dev gonad_e12.5_F_VasAssocMesStromOvary_Sma_top-relative-expression-ranked_500	HGF SCUBE1 FBN2 HMCN1 EGFR	1.58e-04	385	29	5	gudmap_dev gonad_e12.5_F_VasAssocMesStromOvary_Sma_500
CoexpressionAtlas	AravindRamakr_EmbryoidBody-LF_top-relative-expression-ranked_1000_k-means-cluster#4	SCUBE3 SCUBE1 HMCN1 WNT1 FBN3	2.73e-04	433	29	5	Arv_EB-LF_1000_K4
CoexpressionAtlas	dev gonad_e11.5_M_GonadVasMes_Flk_k-means-cluster#3_top-relative-expression-ranked_500	ADAM19 HMCN1	3.37e-04	20	29	2	gudmap_dev gonad_e11.5_M_GonadVasMes_Flk_k3_500
CoexpressionAtlas	DevelopingLowerUrinaryTract_e14.5_ Genital tubercle F_emap-6706_k-means-cluster#3_top-relative-expression-ranked_500	ZNF462 ASXL2 FBN2 EGFR	3.48e-04	249	29	4	gudmap_developingLowerUrinaryTract_e14.5_ Genital tubercle F_500_k3
CoexpressionAtlas	DevelopingKidney_e13.5_podocyte cells_emap-27773_k-means-cluster#3_top-relative-expression-ranked_1000	PTPDC1 ADAM19 EGFR TMEFF2	3.53e-04	250	29	4	gudmap_developingKidney_e13.5_podocyte cells_1000_k3
CoexpressionAtlas	dev gonad_e13.5_M_InterstitTestis_Sma_k-means-cluster#4_top-relative-expression-ranked_200	HMCN1 EGFR	3.72e-04	21	29	2	gudmap_dev gonad_e13.5_M_InterstitTestis_Sma_k4_200
CoexpressionAtlas	dev gonad_e12.5_F_VasAssMesen_MafB_k-means-cluster#3_top-relative-expression-ranked_1000	HGF HMCN1 EGFR	4.13e-04	107	29	3	gudmap_dev gonad_e12.5_F_VasAssMesen_MafB_k3_1000
CoexpressionAtlas	FacebaseRNAseq_e10.5_Neural Epithelium Overlying Medial Eminence_top-relative-expression-ranked_500_k-means-cluster#3	ZNF462 PPP1R10 SCUBE1	4.25e-04	108	29	3	Facebase_RNAseq_e10.5_Neural Epithelium Overlying Medial Eminence_500_K3
CoexpressionAtlas	dev gonad_e13.5_F_VascAssocMesenchStromOvary_MafB_k-means-cluster#2_top-relative-expression-ranked_1000	SCUBE1 FBN2 HMCN1 EGFR	4.41e-04	265	29	4	gudmap_dev gonad_e13.5_F_VascAssocMesenchStromOvary_MafB_k2_1000
CoexpressionAtlas	Progenitor-Cell-Biology-Consortium_induced-Ectoderm_fromBlastocyst-derived-humanEmbryonicStemCells_top-relative-expression-ranked_500	SCUBE3 SCUBE1 WNT1 FBN3 TMEFF2	4.68e-04	487	29	5	PCBC_ECTO_blastocyst_500
CoexpressionAtlas	DevelopingLowerUrinaryTract_e14.5_ Genital tubercle_emap-6706_top-relative-expression-ranked_1000	ZNF462 ASXL2 NUP155 HMCN1 EGFR SPINK5	5.15e-04	769	29	6	gudmap_developingLowerUrinaryTract_e14.5_ Genital tubercle_1000
CoexpressionAtlas	dev gonad_e12.5_F_VasAssMesen_MafB_top-relative-expression-ranked_1000	ADAMTS17 HGF SCUBE1 FBN2 HMCN1 EGFR	5.66e-04	783	29	6	gudmap_dev gonad_e12.5_F_VasAssMesen_MafB_1000
CoexpressionAtlas	ECTO blastocyst_vs_ECTO UCB CD34+Z-Confounder_removed-fold2.0_adjp0.05	ADAM19 FBN2 WNT1 TMEFF2	5.72e-04	284	29	4	PCBC_ratio_ECTO blastocyst_vs_ECTO UCB CD34+Z_cfr-2X-p05
CoexpressionAtlas	DevelopingKidney_e14.5 whole kidney - Wnt4 KO_emap-6674_top-relative-expression-ranked_1000	ZNF462 PTPDC1 XAF1 FBN2 HMCN1 EGFR	5.97e-04	791	29	6	gudmap_developingKidney_e14.5 whole kidney - Wnt4 KO_1000
CoexpressionAtlas	dev gonad_e13.5_M_InterstitTestis_Sma_k-means-cluster#1_top-relative-expression-ranked_100	HGF HMCN1	6.19e-04	27	29	2	gudmap_dev gonad_e13.5_M_InterstitTestis_Sma_k1_100
CoexpressionAtlas	dev gonad_e12.5_F_VasAssocMesStromOvary_Sma_k-means-cluster#4_top-relative-expression-ranked_1000	HGF HMCN1 EGFR	6.51e-04	125	29	3	gudmap_dev gonad_e12.5_F_VasAssocMesStromOvary_Sma_k4_1000
CoexpressionAtlas	dev gonad_e13.5_M_InterstitFLeydig_MafB_k-means-cluster#1_top-relative-expression-ranked_1000	ADAMTS17 SCUBE1 FBN2	6.51e-04	125	29	3	gudmap_dev gonad_e13.5_M_InterstitFLeydig_MafB_k1_1000
CoexpressionAtlas	dev lower uro neuro_e15.5_PelvicGanglion_Sox10_k-means-cluster#2_top-relative-expression-ranked_500	FBN2 HMCN1 EGFR	6.81e-04	127	29	3	gudmap_dev lower uro neuro_e15.5_PelvicGanglion_Sox10_k2_500
CoexpressionAtlas	dev gonad_e12.5_M_InterstitTestis_Sma_k-means-cluster#2_top-relative-expression-ranked_500	HGF HMCN1 EGFR	7.29e-04	130	29	3	gudmap_dev gonad_e12.5_M_InterstitTestis_Sma_k2_500
CoexpressionAtlas	DevelopingKidney_e13.5_podocyte cells_emap-27773_k-means-cluster#4_top-relative-expression-ranked_1000	SCUBE3 NUP155 ADAMTS4 RBM45	8.03e-04	311	29	4	gudmap_developingKidney_e13.5_podocyte cells_1000_k4
CoexpressionAtlas	dev gonad_e11.5_M_GonMes_Sma_top-relative-expression-ranked_1000	HGF SCUBE1 HMCN1 EGFR RNF19A TMEFF2	8.66e-04	849	29	6	gudmap_dev gonad_e11.5_M_GonMes_Sma_1000
CoexpressionAtlas	dev gonad_e13.5_F_VascAssocMesenchStromOvary_MafB_k-means-cluster#1_top-relative-expression-ranked_200	FBN2 HMCN1	9.26e-04	33	29	2	gudmap_dev gonad_e13.5_F_VascAssocMesenchStromOvary_MafB_k1_200
CoexpressionAtlas	dev gonad_e13.5_F_SupCellPrec_Sry_k-means-cluster#3_top-relative-expression-ranked_500	FBN2 HMCN1	9.83e-04	34	29	2	gudmap_dev gonad_e13.5_F_SupCellPrec_Sry_k3_500
CoexpressionAtlas	dev gonad_e13.5_M_InterstitFLeydig_MafB_top-relative-expression-ranked_200	SCUBE1 HMCN1 EGFR	1.02e-03	146	29	3	gudmap_dev gonad_e13.5_M_InterstitFLeydig_MafB_200
CoexpressionAtlas	dev gonad_e12.5_F_VasAssMesen_MafB_k-means-cluster#4_top-relative-expression-ranked_500	SCUBE1 FBN2 HMCN1	1.02e-03	146	29	3	gudmap_dev gonad_e12.5_F_VasAssMesen_MafB_k4_500
CoexpressionAtlas	FacebaseRNAseq_e10.5_Neural Epithelium Overlying Central Eminence_top-relative-expression-ranked_1000_k-means-cluster#3	ZNF462 PPP1R10 PTPDC1 SCUBE1	1.11e-03	339	29	4	Facebase_RNAseq_e10.5_Neural Epithelium Overlying Central Eminence_1000_K3
CoexpressionAtlas	dev gonad_e12.5_M_InterstitTestis_Sma_top-relative-expression-ranked_200	HGF SCUBE1 HMCN1	1.17e-03	153	29	3	gudmap_dev gonad_e12.5_M_InterstitTestis_Sma_200
CoexpressionAtlas	dev gonad_e13.5_M_InterstitTestis_Sma_k-means-cluster#1_top-relative-expression-ranked_500	HGF HMCN1 EGFR	1.24e-03	156	29	3	gudmap_dev gonad_e13.5_M_InterstitTestis_Sma_k1_500
CoexpressionAtlas	dev gonad_e11.5_F_GonadVasMes_Flk_k-means-cluster#3_top-relative-expression-ranked_1000	HGF FBN2 HMCN1 TMEFF2	1.30e-03	354	29	4	gudmap_dev gonad_e11.5_F_GonadVasMes_Flk_k3_1000
CoexpressionAtlas	Endoderm Differentiated Cells_vs_Pluripotent Stem Cells-Confounder_removed-fold2.0_adjp0.05	ASXL1 ADAM19 FBN2 RNF19A FBN3	1.34e-03	615	29	5	PCBC_ratio_DE_vs_SC_cfr-2X-p05
CoexpressionAtlas	FacebaseRNAseq_e10.5_Neural Epithelium Overlying Central Eminence_top-relative-expression-ranked_500_k-means-cluster#5	ZNF462 PPP1R10 SCUBE1	1.38e-03	162	29	3	Facebase_RNAseq_e10.5_Neural Epithelium Overlying Central Eminence_500_K5
CoexpressionAtlas	kidney_P3_CapMes_Crym_top-relative-expression-ranked_200	SCUBE3 FBN2 HMCN1	1.48e-03	166	29	3	gudmap_kidney_P3_CapMes_Crym_200
CoexpressionAtlas	dev gonad_e12.5_M_InterstitTestis_Sma_k-means-cluster#4_top-relative-expression-ranked_200	HGF HMCN1	1.50e-03	42	29	2	gudmap_dev gonad_e12.5_M_InterstitTestis_Sma_k4_200
CoexpressionAtlas	dev lower uro neuro_e15.5_PelvicGanglion_Sox10_top-relative-expression-ranked_500	FBN2 HMCN1 EGFR TMEFF2	1.54e-03	371	29	4	gudmap_dev lower uro neuro_e15.5_PelvicGanglion_Sox10_500
CoexpressionAtlas	AravindRamakr_EmbryoidBody-LF_top-relative-expression-ranked_2500_k-means-cluster#2	SCUBE3 SCUBE1 HMCN1 WNT1 FBN3 TMEFF2	1.56e-03	951	29	6	Arv_EB-LF_2500_K2
CoexpressionAtlas	dev gonad_e12.5_M_InterstitTestis_Sma_top-relative-expression-ranked_500	HGF SCUBE1 HMCN1 EGFR	1.57e-03	373	29	4	gudmap_dev gonad_e12.5_M_InterstitTestis_Sma_500
CoexpressionAtlas	DevelopingKidney_e13.5_podocyte cells_emap-27773_k-means-cluster#3_top-relative-expression-ranked_200	SCUBE3 RBM45	1.72e-03	45	29	2	gudmap_developingKidney_e13.5_podocyte cells_200_k3
CoexpressionAtlas	DevelopingKidney_e14.5 whole kidney - Wnt4 KO_emap-6674_top-relative-expression-ranked_500	PTPDC1 FBN2 HMCN1 EGFR	1.82e-03	388	29	4	gudmap_developingKidney_e14.5 whole kidney - Wnt4 KO_500
CoexpressionAtlas	FacebaseRNAseq_e10.5_Neural Epithelium Overlying Central Eminence_top-relative-expression-ranked_1000	ZNF462 PPP1R10 PTPDC1 XAF1 SCUBE1 WNT1	1.87e-03	986	29	6	Facebase_RNAseq_e10.5_Neural Epithelium Overlying Central Eminence_1000
CoexpressionAtlas	FacebaseRNAseq_e8.5_Paraxial Mesoderm_top-relative-expression-ranked_500_k-means-cluster#1	ADAMTS17 WNT1	1.87e-03	47	29	2	Facebase_RNAseq_e8.5_Paraxial Mesoderm_500_K1
CoexpressionAtlas	kidney_P1_CapMes_Crym_k-means-cluster#1_top-relative-expression-ranked_1000	ADAMTS17 FBN2 HMCN1 DPH6	2.05e-03	401	29	4	gudmap_kidney_P1_CapMes_Crym_k1_1000
CoexpressionAtlas	ECTO blastocyst_vs_ECTO cord blood-Confounder_removed-fold2.0_adjp0.05	ADAM19 WNT1 FBN3	2.14e-03	189	29	3	PCBC_ratio_ECTO blastocyst_vs_ECTO cord blood_cfr-2X-p05
CoexpressionAtlas	kidney single cell_adult_JuxtaGlomCell_Ren1Gfp_StemCellamp_k-means-cluster#1_top-relative-expression-ranked_500	ADAMTS17 SCUBE1 HMCN1	2.27e-03	193	29	3	gudmap_kidney single cell_adult_JuxtaGlomCell_Ren1Gfp_Scamp_k1_500
CoexpressionAtlas	dev gonad_e13.5_M_InterstitFLeydig_MafB_k-means-cluster#2_top-relative-expression-ranked_500	SCUBE1 FBN2	2.29e-03	52	29	2	gudmap_dev gonad_e13.5_M_InterstitFLeydig_MafB_k2_500
CoexpressionAtlas	kidney_P0_CapMes_Crym_k-means-cluster#2_top-relative-expression-ranked_500	ADAMTS17 FBN2 HMCN1	2.30e-03	194	29	3	gudmap_kidney_P0_CapMes_Crym_k2_500
CoexpressionAtlas	DevelopingKidney_e15.5_Ureteral Smooth Musc_emap-28812_k-means-cluster#4_top-relative-expression-ranked_1000	HGF FBN2 TMEFF2	2.34e-03	195	29	3	gudmap_developingKidney_e15.5_Ureteral Smooth Musc_1000_k4
CoexpressionAtlas	DevelopingKidney_e14.5 whole kidney - Wnt4 KO_emap-6674_k-means-cluster#1_top-relative-expression-ranked_1000	ZNF462 PTPDC1 HMCN1	2.34e-03	195	29	3	gudmap_developingKidney_e14.5 whole kidney - Wnt4 KO_1000_k1
CoexpressionAtlas	FacebaseRNAseq_e10.5_Neural Epithelium Overlying Medial Eminence_top-relative-expression-ranked_1000_k-means-cluster#2	ZNF462 PPP1R10 SCUBE1	2.37e-03	196	29	3	Facebase_RNAseq_e10.5_Neural Epithelium Overlying Medial Eminence_1000_K2
CoexpressionAtlas	kidney_P1_CapMes_Crym_k-means-cluster#4_top-relative-expression-ranked_500	ADAMTS17 FBN2 HMCN1	2.37e-03	196	29	3	gudmap_kidney_P1_CapMes_Crym_k4_500
CoexpressionAtlas	dev gonad_e11.5_F_GonadVasMes_Flk_top-relative-expression-ranked_500	HGF SCUBE1 FBN2 TMEFF2	2.49e-03	423	29	4	gudmap_dev gonad_e11.5_F_GonadVasMes_Flk_500
CoexpressionAtlas	DevelopingLowerUrinaryTract_e14.5_ Genital tubercle F_emap-6706_top-relative-expression-ranked_500	ZNF462 ASXL2 FBN2 EGFR	2.59e-03	428	29	4	gudmap_developingLowerUrinaryTract_e14.5_ Genital tubercle F_500
CoexpressionAtlas	DevelopingLowerUrinaryTract_e14.5_ Genital tubercle M_emap-6706_top-relative-expression-ranked_500	ZNF462 ASXL2 FBN2 EGFR	2.62e-03	429	29	4	gudmap_developingLowerUrinaryTract_e14.5_ Genital tubercle M_500
CoexpressionAtlas	dev gonad_e11.5_M_GonMes_Sma_top-relative-expression-ranked_500	HGF SCUBE1 RNF19A TMEFF2	2.68e-03	432	29	4	gudmap_dev gonad_e11.5_M_GonMes_Sma_500
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_2\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ZNF462 FBN2 EGFR TMEFF2	5.69e-06	182	29	4	5e1b316599436740f1b30875f0ebd33c3edfb2b6
ToppCell	droplet-Kidney-KIDNEY-1m-Mesenchymal-Stroma____fibroblast\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ADAMTS17 FBN2 HMCN1 TMEFF2	6.06e-06	185	29	4	785c55d39909fac74415f24427979691e7e694e6
ToppCell	droplet-Kidney-KIDNEY-1m-Mesenchymal\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ADAMTS17 FBN2 HMCN1 TMEFF2	6.06e-06	185	29	4	97a1dcacbc48dc3f41c26fbb59af35c935f894d4
ToppCell	droplet-Kidney-KIDNEY-1m-Mesenchymal-fibroblast\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ADAMTS17 FBN2 HMCN1 TMEFF2	6.20e-06	186	29	4	94d577dbb6bfacf50632e1fe8af041b35a1e6b23
ToppCell	Mild-CD8+_T\|Mild / Disease group and Cell class	ADAMTS17 SCUBE1 WNT1 RNF144A	7.32e-06	194	29	4	c3dba9ff0ab98b6a955b32d071ad7e397dcdc6e9
ToppCell	droplet-Bladder-BLADDER-1m-Epithelial-nan\|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HGF SCUBE1 WNT1	1.02e-04	140	29	3	e442c46979d725ec82f525a001c46d971fcade4d
ToppCell	frontal_cortex-Neuronal-glutamatergic_neuron-L5_IT-L5_IT_ALM_Lypd1_Gpr88\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	HGF SCUBE1 RNF144A	1.42e-04	157	29	3	5aee90ad7aaa65fdabc23597451da5e48db8f4e6
ToppCell	367C-Lymphocytic-NK_cells-NK_cell_B1\|367C / Donor, Lineage, Cell class and subclass (all cells)	UTP20 ASXL2 NUP155	1.53e-04	161	29	3	f470b662566131dfe69a2fd01186ac8491196396
ToppCell	Control-Myeloid-MoAM1,_IL1R2\|Myeloid / Condition, Lineage and Cell class	HGF FBN2 RNF144A	1.71e-04	167	29	3	6e5140527437193f441ca96893b9a00d346614f3
ToppCell	390C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_5\|CD8+_Cytotoxic_T-cell / Donor, Lineage, Cell class and subclass (all cells)	ADAM19 HMCN1 SPINK5	1.74e-04	168	29	3	d7d19c93d1c3dd994e18e28d5f36ae7773ff5d7f
ToppCell	5'-Adult-Appendix-Hematopoietic-T_cells-TRGV2_gdT\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ADAMTS17 ASXL2 RNF19A	1.77e-04	169	29	3	8caf7996796a2e2716e3855de855c903d6126bf2
ToppCell	5'-Adult-LargeIntestine-Mesenchymal-fibroblastic-Stromal_1_(ADAMDEC1+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	HGF LAMB4 FBN2	1.77e-04	169	29	3	c0824a93674e2bff0f09b2d2fab5bab016a2e379
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_1-Inh_L1-6_VIP_PENK\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ADAMTS17 FBN2 EGFR	1.77e-04	169	29	3	eb3b8e473192c4b8688f2f8da400116dd6fe193d
ToppCell	Primary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_1-Inh_L1-6_VIP_PENK\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ADAMTS17 FBN2 EGFR	1.80e-04	170	29	3	25d7c61601057fd64d2634fa898b3e56b9de0bc1
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_1-Inh_L1-3_VIP_ACHE\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ADAMTS17 EGFR FBN3	1.80e-04	170	29	3	36dbbdb13f69307afd2122ff051b2980850c1f00
ToppCell	5'-Adult-LymphNode-Hematopoietic-T_cells-TRGV2_gdT\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ADAMTS17 ASXL2 WNT1	1.90e-04	173	29	3	79d11f94a8f6a420c18c2fef0da77e9af3204765
ToppCell	wk_15-18-Mesenchymal-Fibroblast-Mesenchymal_3\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	ADAMTS17 SCUBE3 TMEFF2	1.90e-04	173	29	3	b43817a6b1ed8d6b5366702343be4311c0d52d83
ToppCell	5'-Adult-Appendix-Mesenchymal-fibroblastic-Stromal_1_(CCL11+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	HGF FBN2 EGFR	1.93e-04	174	29	3	f90ca117b729436cf452e2ddcec26ba525c5c13b
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Intercalated_Cell_Type_B\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	ASXL1 EGFR FBN3	2.00e-04	176	29	3	6c7edf1cb38644500bce6c5a1dd90bbe17415cdb
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ZNF462 FBN2 EGFR	2.00e-04	176	29	3	327a3e81b724252e36d786de92a3ffd721ea6d7b
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Intercalated_Cell_Type_B\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ASXL1 EGFR FBN3	2.06e-04	178	29	3	51d2188406f04329311b2efd1108fc36617a860e
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Intercalated_Cell_Type_B\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	ASXL1 EGFR FBN3	2.13e-04	180	29	3	cfc8bfbfd3617aabbb49f9730c29b673ca157e74
ToppCell	severe-CD8+_T_naive\|severe / disease stage, cell group and cell class	PPP1R10 RBM45 RNF144A	2.13e-04	180	29	3	94fe530367b170777f4051a4034cff06d80dbb83
ToppCell	5'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-myocytic_fibroblast-Myofibroblasts-Myofibroblasts_L.2.3.2.2\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	SCUBE1 HMCN1 ADAMTS4	2.17e-04	181	29	3	b116c68393d8836bac080f81a8fcbeb52e0403e7
ToppCell	Somatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_2-Inh_L2-5_VIP_TOX2\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	FBN2 EGFR FBN3	2.17e-04	181	29	3	154d5e586cab25155c6d06dfe6ae01203b88e0fb
ToppCell	10x5'-Liver-Lymphocytic_T_CD4-T_CD4/CD8\|Liver / Manually curated celltypes from each tissue	PPP1R10 ADAM19 RNF19A	2.17e-04	181	29	3	f2315414e714ac86211546a935660c4be6e85f1b
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_2-Inh_L2-5_VIP_TOX2\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	FBN2 EGFR FBN3	2.17e-04	181	29	3	35bcdcd2651149692e5b150e887c0f450c81d2d4
ToppCell	severe-CD8+_T_naive\|World / disease stage, cell group and cell class	PPP1R10 RBM45 RNF144A	2.17e-04	181	29	3	69eeeb7f326e230b07495d557f708fbe3312ac0a
ToppCell	primary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_2-Inh_L1-3_VIP_ZNF322P1\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ADAMTS17 EGFR FBN3	2.20e-04	182	29	3	d3a037268f026eb2f84428b1821022503cef7756
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_2\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	ADAMTS17 SCUBE3 HMCN1	2.20e-04	182	29	3	5f513bbb7125956eb528e3120de3fd776770a7c3
ToppCell	PBMC-Mild-cDC_9\|Mild / Compartment, Disease Groups and Clusters	UTP20 SCUBE1 ADAM19	2.27e-04	184	29	3	2e0c9a2c40c892a2d435eafb31f1f838de9baf15
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_2-Inh_L1-3_VIP_ZNF322P1\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ADAMTS17 EGFR FBN3	2.31e-04	185	29	3	0b5a0df58ae2ad8261f40f152775747af4f3937a
ToppCell	kidney_cells-Adult_normal_reference-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	HGF ADAM19 ADAMTS4	2.31e-04	185	29	3	e1fbec55b71f604189eb2431768fadbaa0453a83
ToppCell	kidney_cells-Adult_normal_reference-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast-\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	HGF ADAM19 ADAMTS4	2.31e-04	185	29	3	9d933cd5ebc8368fd37aa83113d2dfa6938ff72d
ToppCell	CV-Moderate-7\|Moderate / Virus stimulation, Condition and Cluster	ADAM19 NUP155 RNF19A	2.31e-04	185	29	3	a6c9203ce6c2892a4a369c9bcfb85720f01cbb3f
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L5-6_PVALB_STON2\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ADAMTS17 HGF FBN2	2.31e-04	185	29	3	f4ac62009c0ad3346e71b809e17727303c4df153
ToppCell	(2)_Fibroblasts-(20)_Fibro-1\|(2)_Fibroblasts / Cell class and subclass of bone marrow stroma cells in homeostatis	ADAM19 HMCN1 TMEFF2	2.35e-04	186	29	3	e93415b59dd89bc8a966dab0e0b65fe215933598
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_2\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	ZNF462 FBN2 EGFR	2.35e-04	186	29	3	5c4ffe4e4d5536ae9f8794277fe032c693e7dd56
ToppCell	5'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2-Alveolar_fibroblasts-Alveolar_fibroblasts_L.2.1.1.1\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	HGF HMCN1 ADAMTS4	2.35e-04	186	29	3	5473283fb95cee556b1f6934cf72169b676b5bcc
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	ADAMTS17 LAMB4 HMCN1	2.38e-04	187	29	3	77886f99c229610abd28c4c370d2c7d1536c9782
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ZNF462 FBN2 EGFR	2.42e-04	188	29	3	63a4b25a0a6e05f80f1a6dd91b817f3cf49e6b68
ToppCell	5'-Adult-LargeIntestine-Mesenchymal-fibroblastic-Stromal_2_(NPY+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	HGF SCUBE1 FBN2	2.42e-04	188	29	3	997dcfc4f08738ab398d8abc15e4fd2fc6619862
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	ADAMTS17 LAMB4 HMCN1	2.42e-04	188	29	3	3cee9916399e2e7580cecbcbb27424a71e7e7ac0
ToppCell	LV-14._Fibroblast_III\|World / Chamber and Cluster_Paper	ADAMTS4 EGFR RNF19A	2.46e-04	189	29	3	3922135d1f6fc768d71ba3b465585fead6ea68a8
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	ADAMTS17 LAMB4 HMCN1	2.46e-04	189	29	3	f51cdc9a47371cab8ed9ae63a6f14da07ede446c
ToppCell	3'-Airway_Nasal-Epithelial-Airway_epithelium-respiratory_basal_cell\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	LAMB4 EGFR SPINK5	2.46e-04	189	29	3	c80610395d016acc855cfa451e47ea6cecb0556c
ToppCell	Primary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5-Inh_L1-6_LAMP5_CA13_(Lamp5_Lhx6_1)\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ZNF462 FBN2 EGFR	2.50e-04	190	29	3	2f54da2bee411f8868348a4c37034184b8f58a89
ToppCell	droplet-Kidney-nan-3m-Mesenchymal-fibroblast\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ADAMTS4 WNT1 TMEFF2	2.50e-04	190	29	3	f61e21d53f2f7804ac6e40ab6c7f69838aa94d6a
ToppCell	3'-Airway_Nasal-Epithelial-Airway_epithelium-respiratory_basal_cell-Suprabasal\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	LAMB4 EGFR SPINK5	2.50e-04	190	29	3	83eb0151226b3f5a7dae994a1a519285f9bf6e82
ToppCell	PND01-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2-AF2_mature\|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	FBN2 HMCN1 TMEFF2	2.50e-04	190	29	3	947807863a9b247c301c6cf63d6fd5a2c8018e66
ToppCell	E18.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2-AF2_mature\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	FBN2 HMCN1 EGFR	2.54e-04	191	29	3	75d2197076a9dfc868e8baf95bd4c5e44f438e3e
ToppCell	Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)\|World / Lineage, Cell type, age group and donor	EGFR FBN3 TMEFF2	2.54e-04	191	29	3	d3733c8c4bda70c4390e5601fdda6188a64be944
ToppCell	E18.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	FBN2 HMCN1 EGFR	2.54e-04	191	29	3	4b50fdd310701251e64e16cd2d07ce03dbfd3e3e
ToppCell	CD8+_Memory_T_cell-CV-7\|CD8+_Memory_T_cell / cell class, Virus stimulation and cluster	ADAM19 NUP155 RNF19A	2.54e-04	191	29	3	9454f642c3621370fa23640b631301346b300950
ToppCell	3'-Airway_Nasal-Epithelial-Airway_epithelium\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	LAMB4 EGFR SPINK5	2.54e-04	191	29	3	c5aaf795dccc94ff0c66d08d5525abe2a5f8b98e
ToppCell	facs-Lung-nan-3m-Endothelial-Capillary_endothelial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SCUBE1 HMCN1 RNF144A	2.58e-04	192	29	3	4bab9754cfd8b9c2d7cc1490e8a29f58c3c26f6c
ToppCell	wk_08-11-Mesenchymal-Fibroblast-Mesenchymal_3\|wk_08-11 / Celltypes from embryonic and fetal-stage human lung	SCUBE3 HGF TMEFF2	2.58e-04	192	29	3	d88753b200d9c8da6716222d697ddf0a1548d6c8
ToppCell	primary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ZNF462 FBN2 EGFR	2.58e-04	192	29	3	f6ec683b2133b3095a1fcc06ca8605cf38f774b5
ToppCell	primary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_1\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ZNF462 FBN2 EGFR	2.58e-04	192	29	3	690b3d17c481159bc96b8bc7f6a66b51343ee858
ToppCell	LA-14._Fibroblast_III\|LA / Chamber and Cluster_Paper	ADAMTS17 ADAMTS4 EGFR	2.62e-04	193	29	3	7426c291bac59e539c427bcaae18abc7d397d44e
ToppCell	Primary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic-i_Gaba_1\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ZNF462 FBN2 EGFR	2.62e-04	193	29	3	294cb5b580bb83fe0eb04f112d5507aac35d4d44
ToppCell	Primary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ZNF462 FBN2 EGFR	2.62e-04	193	29	3	3d3c45d5ff6f3396a1990615aae9fe176e799994
ToppCell	10x3'2.3-week_17-19-Mesenchymal_myocytic-stroma-myofibroblast\|week_17-19 / cell types per 3 fetal stages;per 3',per 5'	EGFR FBN3 TMEFF2	2.62e-04	193	29	3	02dfd1df1e7fc84bfca2b0c95138b5b4408bb5d1
ToppCell	COVID-19-kidney-FLT1+PLVAP+EC\|kidney / Disease (COVID-19 only), tissue and cell type	SCUBE1 ADAM19 ADAMTS4	2.62e-04	193	29	3	479abb1cd2eb978b8a4fdb900069a6329fc8cade
ToppCell	RV-09._Endothelium_I\|World / Chamber and Cluster_Paper	XAF1 HMCN1 SPINK5	2.62e-04	193	29	3	e3fa47e2c7cd8a5b69186711c57751f2296de8ae
ToppCell	TCGA-Stomach-Primary_Tumor-Stomach_Adenocarcinoma-Stomach_Adenocarcinoma_-_NOS-3\|TCGA-Stomach / Sample_Type by Project: Shred V9	HGF HMCN1 RNF144A	2.66e-04	194	29	3	2260cd817a6661e5eb6645b0c6786e18fd58371e
ToppCell	RV-09._Endothelium_I\|RV / Chamber and Cluster_Paper	XAF1 HMCN1 SPINK5	2.66e-04	194	29	3	7b408096e717f2327c12aea35a8d5fc4621d3b06
ToppCell	LA-14._Fibroblast_III\|World / Chamber and Cluster_Paper	ADAMTS17 ADAMTS4 EGFR	2.66e-04	194	29	3	803fa83ceada17c38ca9f933b888f7e7b0b90761
ToppCell	LV-14._Fibroblast_III\|LV / Chamber and Cluster_Paper	ADAMTS4 EGFR RNF19A	2.66e-04	194	29	3	927c26aea0147f7a4b8fb3f192de4de263f1b978
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell_\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	XAF1 SCUBE1 ADAMTS4	2.70e-04	195	29	3	818bc18c5834238e5f733cac6fe928ed0788f57d
ToppCell	COPD-Stromal-Myofibroblast\|COPD / Disease state, Lineage and Cell class	HMCN1 ADAMTS4 EGFR	2.74e-04	196	29	3	af206bb5bbb8b604a6212acd79878bcc3d326cec
ToppCell	Parenchyma_Control_(B.)-Epithelial-TX-Basal_3\|Parenchyma_Control_(B.) / Sample group, Lineage and Cell type	SCUBE3 SCUBE1 FBN3	2.78e-04	197	29	3	2cff37f9d33951840a8f52ccbba6ca1a4bbe3ad9
ToppCell	Lung_Parenchyma-Control-Epithelial-Epithelial-Basal_3\|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)	SCUBE3 SCUBE1 FBN3	2.78e-04	197	29	3	4f8f23b1ef2eae9d300bd2c1a5cb7ef0163858a1
ToppCell	mild-Treg\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	ASXL1 XAF1 RNF19A	2.78e-04	197	29	3	39800e6e83f2d333b753d121c7aeb2912b91faa2
ToppCell	3'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2-Alveolar_fibroblasts-Alveolar_fibroblasts_L.2.1.1.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	HGF HMCN1 ADAMTS4	2.78e-04	197	29	3	94a9603cbd3516fbcce871909693b88f20d41713
ToppCell	10x3'2.3-week_17-19-Mesenchymal_adipo-stroma\|week_17-19 / cell types per 3 fetal stages;per 3',per 5'	ZNF462 SCUBE1 EGFR	2.78e-04	197	29	3	b9745e382baa2725dfcae060701fb53f6c8a31fa
ToppCell	Tracheal-10x5prime-Stromal-Peri/Epineurial_\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	SCUBE3 SCUBE1 FBN2	2.78e-04	197	29	3	2cb1f557ce1400398975de94638126b4522567f3
ToppCell	COPD-Stromal-Myofibroblast\|World / Disease state, Lineage and Cell class	HMCN1 ADAMTS4 EGFR	2.78e-04	197	29	3	d51f484b4e01ac64233950d0b97fa88825ea1dbb
ToppCell	5'-GW_trimst-2-SmallIntestine-Mesenchymal-fibroblastic-Stromal_2_(NPY+)\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SCUBE3 FBN2 EGFR	2.78e-04	197	29	3	1da8ba5bbab232add6e43ad78b15c2339d0c2bc3
ToppCell	10x3'2.3-week_17-19-Mesenchymal_adipo\|week_17-19 / cell types per 3 fetal stages;per 3',per 5'	ZNF462 SCUBE1 EGFR	2.78e-04	197	29	3	5afddde4e2b5cd55abe11e9b9efae02dbdc3da3a
ToppCell	10x3'2.3-week_17-19-Mesenchymal_adipo-stroma-adipo-CAR\|week_17-19 / cell types per 3 fetal stages;per 3',per 5'	ZNF462 SCUBE1 EGFR	2.78e-04	197	29	3	1baffd087ca194a7355fefbb3bf67befb14fe2de
ToppCell	Lung_Parenchyma-Control-Epithelial-Epithelial-Basal_3-\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	SCUBE3 SCUBE1 FBN3	2.78e-04	197	29	3	0f37afad46b94c748a149d9ee681472d7a3e6937
ToppCell	Tracheal-NucSeq-Stromal-Myofibroblastic\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	SCUBE1 ADAM19 ADAMTS4	2.82e-04	198	29	3	c12e7511628db819a52959bb68580e27c00c2e41
ToppCell	Parenchymal-10x5prime-Stromal-Fibroblastic-Fibro_peribronchial\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	HGF SCUBE1 HMCN1	2.82e-04	198	29	3	300d7cc56207d77168390fa1ffcbcf76767b1b80
ToppCell	Control-Control-Lymphocyte-T/NK-CD4+_T_activated\|Control / Disease, condition lineage and cell class	SCUBE3 ASXL1 XAF1	2.82e-04	198	29	3	ee71543559836fd59adc0da877b2ca538cba60cb
ToppCell	wk_20-22-Endothelial-Blood_vessel_endothelial-Venous_endo\|wk_20-22 / Celltypes from embryonic and fetal-stage human lung	SCUBE3 HMCN1 SPINK5	2.86e-04	199	29	3	70e05d7c0c68c28754ce0e72434b205aed6287ae
ToppCell	Tracheal-10x5prime-Stromal-Peri/Epineurial_-NAF_epineurial\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	SCUBE3 SCUBE1 TMEFF2	2.86e-04	199	29	3	fbec5c034576cb1adaf05f6f97cc5525d19e0c1b
ToppCell	3'-GW_trimst-1.5-SmallIntestine-Mesenchymal-fibroblastic\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SCUBE3 HGF FBN2	2.86e-04	199	29	3	137ff58897e6ada8a5a70205f66fe9110795506b
ToppCell	Neuronal-Inhibitory-iA-iA_3(VIP)-VIP_3-CCDC184-L1-3\|Neuronal / cells hierarchy compared to all cells using T-Statistic	ADAMTS17 EGFR FBN3	2.90e-04	200	29	3	140aff451cd58e1d544ee668e49e37e577f6f068
ToppCell	Neuronal-Inhibitory-iA-iA_2(LAMP5)-CA1-\|Neuronal / cells hierarchy compared to all cells using T-Statistic	ZNF462 FBN2 EGFR	2.90e-04	200	29	3	ca5401b76ab014080914bf78042d368cf318effa
ToppCell	Neuronal-Inhibitory-iB-iB_3(PVALB-SST)-MIR548F2--L5-6\|Neuronal / cells hierarchy compared to all cells using T-Statistic	ADAMTS17 HGF FBN2	2.90e-04	200	29	3	3cbb01039d1e7635ec4dcdf0223587f7ea3c7b34
ToppCell	Neuronal-Inhibitory-iA-iA_2(LAMP5)-CA1\|Neuronal / cells hierarchy compared to all cells using T-Statistic	ZNF462 FBN2 EGFR	2.90e-04	200	29	3	40286010bd17cf9e34ecd5440953b072ebfae208
ToppCell	Neuronal-Inhibitory-iA-iA_3(VIP)-VIP_2-TYR\|Neuronal / cells hierarchy compared to all cells using T-Statistic	FBN2 EGFR FBN3	2.90e-04	200	29	3	bfdafb024a7b20d46837b2e6480dd4929253cd62
ToppCell	Neuronal-Inhibitory-iA-iA_3(VIP)-VIP_2-TYR-L2-5\|Neuronal / cells hierarchy compared to all cells using T-Statistic	FBN2 EGFR FBN3	2.90e-04	200	29	3	04954fbe1e2264077228bb582c9a5897a70e6da2
ToppCell	Neuronal-Inhibitory-iB-iB_3(PVALB-SST)-MIR548F2-\|Neuronal / cells hierarchy compared to all cells using T-Statistic	ADAMTS17 HGF FBN2	2.90e-04	200	29	3	97a010a1b6d551239cf6ea5a43319fb413ff180e
ToppCell	Neuronal-Inhibitory-iA-iA_3(VIP)-VIP_3-CCDC184\|Neuronal / cells hierarchy compared to all cells using T-Statistic	ADAMTS17 EGFR FBN3	2.90e-04	200	29	3	85bfa7f4dd07a4d4a88330e88f5886fd1ecfdeeb
ToppCell	Parenchymal-NucSeq-Stromal-Fibroblastic-Fibro_alveolar\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	ADAMTS17 HGF HMCN1	2.90e-04	200	29	3	34f52003988ce6329d8deeee1ab875fa77e01e9d
ToppCell	Biopsy_Other_PF-Mesenchymal\|Biopsy_Other_PF / Sample group, Lineage and Cell type	HGF HMCN1 ADAMTS4	2.90e-04	200	29	3	d6fcdd48858b53b5a8d18ae14b2dc4d9af41b070
ToppCell	Neuronal-Inhibitory-iA-iA_2(LAMP5)-CA1--L2-6\|Neuronal / cells hierarchy compared to all cells using T-Statistic	ZNF462 FBN2 EGFR	2.90e-04	200	29	3	70c47d3bbe67d88c5b9dff99c33a603d25fa2ab0
ToppCell	Neuronal-Inhibitory-iB-iB_3(PVALB-SST)-MIR548F2\|Neuronal / cells hierarchy compared to all cells using T-Statistic	ADAMTS17 HGF FBN2	2.90e-04	200	29	3	8ccf2dbbe34b26fbf2bbef1e64b4ae636edd6672
Disease	connective tissue disease (implicated_via_orthology)	FBN2 FBN3	2.60e-06	3	28	2	DOID:65 (implicated_via_orthology)
Disease	refractive error	ZNF462 RBM45 FBN3 NPLOC4	2.43e-04	326	28	4	MONDO_0004892
Disease	Neoplasm Recurrence, Local	ASXL1 EGFR	6.30e-04	39	28	2	C0027643
Disease	diabetes mellitus (is_marker_for)	HGF EGFR	6.96e-04	41	28	2	DOID:9351 (is_marker_for)
Disease	high grade glioma (is_marker_for)	HGF EGFR	7.30e-04	42	28	2	DOID:3070 (is_marker_for)
Disease	FEV/FEC ratio	SCUBE3 ASXL1 ADAM19 HMCN1 RNF19A NPLOC4	8.79e-04	1228	28	6	EFO_0004713
Disease	peak expiratory flow	ADAMTS17 PTPDC1 ADAM19 FBN3	1.19e-03	498	28	4	EFO_0009718
Disease	diabetic retinopathy (is_marker_for)	HGF EGFR	1.21e-03	54	28	2	DOID:8947 (is_marker_for)
Disease	cortical surface area measurement	HGF SCUBE1 FBN2 EGFR FBN3 NPLOC4	1.41e-03	1345	28	6	EFO_0010736
Disease	rheumatoid arthritis (is_marker_for)	HGF ADAMTS4	1.96e-03	69	28	2	DOID:7148 (is_marker_for)
Disease	Colorectal Neoplasms	XAF1 FBN2 EGFR	2.25e-03	277	28	3	C0009404
Disease	age of onset of asthma	SCUBE3 ADAM19	2.56e-03	79	28	2	OBA_2001001
Disease	central corneal thickness	ADAMTS17 FBN2 NPLOC4	3.07e-03	309	28	3	EFO_0005213
Disease	Glioma	XAF1 EGFR	3.09e-03	87	28	2	C0017638
Disease	Abnormality of refraction	ZNF462 FBN2 FBN3 NPLOC4	3.55e-03	673	28	4	HP_0000539
Disease	corpus callosum volume measurement	HGF EGFR	4.06e-03	100	28	2	EFO_0010299
Disease	Colorectal Carcinoma	XAF1 ADAM19 FBN2 EGFR	4.13e-03	702	28	4	C0009402

Protein segments in the cluster

Peptide	Gene	Start	Entry
FGNCGKDMNGEHRKC	ADAM19	551	Q9H013
KDSCYNMMQCIAAGH	DPH6	11	Q7L8W6
GGNNCMDMRKSVCFR	FBN3	1641	Q75N90
KAMIMCQGCGAFCHD	ASXL1	1511	Q8IXJ9
AMIMCKGCGAFCHDD	ASXL2	1406	Q76L83
GMNATFCRNMEHLMC	ADAMTS17	481	Q8TE56
SSQACRAMEEMHGQC	RBM45	76	Q8IUH3
PDGKMHGNLCSMCQA	SPINK5	321	Q9NQ38
DGKMHGNKCAMCASV	SPINK5	521	Q9NQ38
FMNQPGTGHCEMCSL	NPLOC4	591	Q8TAT6
ACMKNCGRRFHNEVG	GGA3	71	Q9NZ52
CMTCNGESYRGLMDH	HGF	211	P14210
HMACSMACGGRACKY	PTPDC1	51	A2A3K4
QFGHMQCNCMMGVFP	NUP155	96	O75694
EGCAQMMCKNCKHAF	RNF144A	196	P50876
VHCGPNRMCFNMRGS	HMCN1	5481	Q96RW7
MSMDFQNHLGSCQKC	EGFR	176	P00533
CMGGRCLHMDQLQDF	ADAMTS4	501	O75173
CFHQGNSQCSRLMMH	HIGD2B	66	Q4VC39
FCNGHASECRPMQKM	LAMB4	266	A4D0S4
VNGGHNCMDMRKSFC	FBN2	1726	P35556
CIHRSNEGMNCMNKD	SCUBE1	156	Q8IWY4
NEGMNCMNKDHGCAH	SCUBE1	161	Q8IWY4
EEGMNCMNKNHGCAH	SCUBE3	156	Q8IX30
MCKGVRNMFHSCTGQ	UTP20	231	O75691
GFCMHGKCEHSINMQ	TMEFF2	271	Q9UIK5
MNDGSCNHMTCAVCG	RNF19A	311	Q9NV58
LCQGCGQFIMHRMLA	XAF1	111	Q6GPH4
FSEMRQECKCHGMSG	WNT1	211	P04628
NIMMHEGFGKVFSCQ	ZNF462	151	Q96JM2
VCRHFMMKGNCRYEN	PPP1R10	911	Q96QC0