Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	ryanodine-sensitive calcium-release channel activity	RYR1 RYR2 RYR3	4.42e-06	4	208	3	GO:0005219
GeneOntologyMolecularFunction	ligand-gated calcium channel activity	RYR1 RYR2 RYR3 TRPV1 GRIN2A	1.59e-05	31	208	5	GO:0099604
GeneOntologyMolecularFunction	calcium-induced calcium release activity	RYR1 RYR2 RYR3	2.18e-05	6	208	3	GO:0048763
GeneOntologyMolecularFunction	intracellularly gated calcium channel activity	RYR1 RYR2 RYR3 TRPV1	3.12e-05	18	208	4	GO:0015278
GeneOntologyMolecularFunction	minus-end-directed microtubule motor activity	DNAH6 DYNC1H1 DNHD1 DNAH7	3.12e-05	18	208	4	GO:0008569
GeneOntologyMolecularFunction	calcium channel activity	RYR1 RYR2 RYR3 PKD1 CACNA1H TRPV1 TMC2 GRIN2A	6.28e-05	129	208	8	GO:0005262
GeneOntologyMolecularFunction	monoatomic cation channel activity	ASIC3 RYR1 RYR2 RYR3 SCN1A PKD1 CACNA1H TRPV1 TMC2 GRIN2A KCNG3 HVCN1 KCNK10	6.69e-05	343	208	13	GO:0005261
GeneOntologyMolecularFunction	[heparan sulfate]-glucosamine 3-sulfotransferase 3 activity	HS3ST3B1 HS3ST3A1	1.08e-04	2	208	2	GO:0033872
GeneOntologyMolecularFunction	voltage-gated monoatomic ion channel activity	RYR1 SCN1A CACNA1H TRPV1 TMC2 GRIN2A KCNG3 HVCN1 KCNK10	1.27e-04	182	208	9	GO:0005244
GeneOntologyMolecularFunction	voltage-gated channel activity	RYR1 SCN1A CACNA1H TRPV1 TMC2 GRIN2A KCNG3 HVCN1 KCNK10	1.38e-04	184	208	9	GO:0022832
GeneOntologyMolecularFunction	calcium ion transmembrane transporter activity	RYR1 RYR2 RYR3 PKD1 CACNA1H TRPV1 TMC2 GRIN2A	1.88e-04	151	208	8	GO:0015085
GeneOntologyMolecularFunction	dynein light intermediate chain binding	DNAH6 DYNC1H1 DNHD1 DNAH7	1.92e-04	28	208	4	GO:0051959
GeneOntologyMolecularFunction	voltage-gated monoatomic cation channel activity	RYR1 CACNA1H TRPV1 TMC2 GRIN2A KCNG3 HVCN1 KCNK10	1.97e-04	152	208	8	GO:0022843
GeneOntologyMolecularFunction	gated channel activity	ASIC3 RYR1 RYR2 RYR3 SCN1A CACNA1H TRPV1 TMC2 GRIN2A KCNG3 HVCN1 KCNK10	2.10e-04	334	208	12	GO:0022836
GeneOntologyMolecularFunction	structural constituent of synapse-associated extracellular matrix	LAMB1 LAMB2	3.22e-04	3	208	2	GO:0150043
GeneOntologyMolecularFunction	phenanthrene-9,10-epoxide hydrolase activity	AKR7L AKR7A3	3.22e-04	3	208	2	GO:0019119
GeneOntologyMolecularFunction	phenanthrene-epoxide hydrolase activity	AKR7L AKR7A3	3.22e-04	3	208	2	GO:0019118
GeneOntologyMolecularFunction	intracellularly ligand-gated monoatomic ion channel activity	RYR1 RYR2 RYR3 TRPV1	3.69e-04	33	208	4	GO:0005217
GeneOntologyMolecularFunction	metal ion transmembrane transporter activity	ASIC3 RYR1 RYR2 RYR3 SCN1A PKD1 CACNA1H TRPV1 TMC2 SLC39A3 GRIN2A KCNG3 SLC9A3 KCNK10	3.89e-04	465	208	14	GO:0046873
GeneOntologyMolecularFunction	microtubule minus-end binding	TUBGCP2 NUMA1 MACF1	4.62e-04	15	208	3	GO:0051011
GeneOntologyMolecularFunction	dynein intermediate chain binding	DNAH6 DYNC1H1 DNHD1 DNAH7	5.77e-04	37	208	4	GO:0045505
GeneOntologyMolecularFunction	microtubule motor activity	KIF9 DNAH6 DYNC1H1 DNHD1 DNAH7	8.17e-04	70	208	5	GO:0003777
GeneOntologyMolecularFunction	transferase activity, transferring sulphur-containing groups	SULT2A1 HS3ST3B1 HS3ST3A1 CHST3 UBA6	1.05e-03	74	208	5	GO:0016782
GeneOntologyMolecularFunction	monoatomic ion channel activity	ASIC3 RYR1 RYR2 RYR3 SCN1A PKD1 CACNA1H TRPV1 TMC2 GRIN2A KCNG3 HVCN1 KCNK10	1.09e-03	459	208	13	GO:0005216
GeneOntologyMolecularFunction	voltage-gated calcium channel activity	RYR1 CACNA1H TRPV1 TMC2	1.33e-03	46	208	4	GO:0005245
GeneOntologyMolecularFunction	cytoskeletal motor activity	MYO9A KIF9 DNAH6 DYNC1H1 DNHD1 DNAH7	1.49e-03	118	208	6	GO:0003774
GeneOntologyMolecularFunction	monoatomic cation transmembrane transporter activity	ASIC3 RYR1 RYR2 RYR3 SCN1A PKD1 CACNA1H ATP13A3 TRPV1 TMC2 SLC39A3 GRIN2A KCNG3 HVCN1 SLC9A3 KCNK10	1.65e-03	664	208	16	GO:0008324
Domain	Ryanodine_rcpt	RYR1 RYR2 RYR3	1.30e-06	3	205	3	IPR003032
Domain	Laminin_IV_B	LAMB4 LAMB1 LAMB2	1.30e-06	3	205	3	IPR013015
Domain	Ryanrecept_TM4-6	RYR1 RYR2 RYR3	1.30e-06	3	205	3	IPR009460
Domain	srGAP2	SRGAP2C SRGAP2 SRGAP2B	1.30e-06	3	205	3	IPR030252
Domain	RyR	RYR1 RYR2 RYR3	1.30e-06	3	205	3	PF02026
Domain	LAMININ_IVB	LAMB4 LAMB1 LAMB2	1.30e-06	3	205	3	PS51116
Domain	RR_TM4-6	RYR1 RYR2 RYR3	1.30e-06	3	205	3	PF06459
Domain	Ryan_recept	RYR1 RYR2 RYR3	1.30e-06	3	205	3	IPR013333
Domain	Dynein_HC_stalk	DNAH6 DYNC1H1 DNHD1 DNAH7	1.29e-05	14	205	4	IPR024743
Domain	Dynein_heavy_dom-2	DNAH6 DYNC1H1 DNHD1 DNAH7	1.29e-05	14	205	4	IPR013602
Domain	DHC_N2	DNAH6 DYNC1H1 DNHD1 DNAH7	1.29e-05	14	205	4	PF08393
Domain	MT	DNAH6 DYNC1H1 DNHD1 DNAH7	1.29e-05	14	205	4	PF12777
Domain	DHC_fam	DNAH6 DYNC1H1 DNHD1 DNAH7	1.75e-05	15	205	4	IPR026983
Domain	Dynein_heavy	DNAH6 DYNC1H1 DNHD1 DNAH7	1.75e-05	15	205	4	PF03028
Domain	Dynein_heavy_dom	DNAH6 DYNC1H1 DNHD1 DNAH7	1.75e-05	15	205	4	IPR004273
Domain	Laminin_N	USH2A LAMB4 LAMB1 LAMB2	2.31e-05	16	205	4	IPR008211
Domain	LamNT	USH2A LAMB4 LAMB1 LAMB2	2.31e-05	16	205	4	SM00136
Domain	LAMININ_NTER	USH2A LAMB4 LAMB1 LAMB2	2.31e-05	16	205	4	PS51117
Domain	Laminin_N	USH2A LAMB4 LAMB1 LAMB2	2.31e-05	16	205	4	PF00055
Domain	RIH_assoc-dom	RYR1 RYR2 RYR3	2.54e-05	6	205	3	IPR013662
Domain	Ins145_P3_rec	RYR1 RYR2 RYR3	2.54e-05	6	205	3	PF08709
Domain	RIH_assoc	RYR1 RYR2 RYR3	2.54e-05	6	205	3	PF08454
Domain	RIH_dom	RYR1 RYR2 RYR3	2.54e-05	6	205	3	IPR000699
Domain	Ins145_P3_rcpt	RYR1 RYR2 RYR3	2.54e-05	6	205	3	IPR014821
Domain	Ryanodine_recept-rel	RYR1 RYR2 RYR3	2.54e-05	6	205	3	IPR015925
Domain	-	RYR1 RYR2 RYR3	2.54e-05	6	205	3	1.25.10.30
Domain	RYDR_ITPR	RYR1 RYR2 RYR3	2.54e-05	6	205	3	PF01365
Domain	Ion_trans_dom	RYR1 RYR2 RYR3 SCN1A CACNA1H TRPV1 KCNG3 HVCN1	3.74e-05	114	205	8	IPR005821
Domain	Ion_trans	RYR1 RYR2 RYR3 SCN1A CACNA1H TRPV1 KCNG3 HVCN1	3.74e-05	114	205	8	PF00520
Domain	EGF_Lam	SCARF2 USH2A LAMB4 LAMB1 LAMB2	3.77e-05	35	205	5	SM00180
Domain	Laminin_EGF	SCARF2 USH2A LAMB4 LAMB1 LAMB2	3.77e-05	35	205	5	PF00053
Domain	Laminin_EGF	SCARF2 USH2A LAMB4 LAMB1 LAMB2	5.67e-05	38	205	5	IPR002049
Domain	FCH	SRGAP2C SRGAP3 SRGAP2 SRGAP2B	8.83e-05	22	205	4	PF00611
Domain	FCH	SRGAP2C SRGAP3 SRGAP2 SRGAP2B	8.83e-05	22	205	4	SM00055
Domain	FCH_dom	SRGAP2C SRGAP3 SRGAP2 SRGAP2B	1.06e-04	23	205	4	IPR001060
Domain	MIR	RYR1 RYR2 RYR3	1.48e-04	10	205	3	PF02815
Domain	MIR_motif	RYR1 RYR2 RYR3	1.48e-04	10	205	3	IPR016093
Domain	MIR	RYR1 RYR2 RYR3	1.48e-04	10	205	3	PS50919
Domain	MIR	RYR1 RYR2 RYR3	1.48e-04	10	205	3	SM00472
Domain	F_BAR	SRGAP2C SRGAP3 SRGAP2 SRGAP2B	1.49e-04	25	205	4	IPR031160
Domain	F_BAR	SRGAP2C SRGAP3 SRGAP2 SRGAP2B	1.49e-04	25	205	4	PS51741
Domain	DHR-1_domain	DOCK5 DOCK6 DOCK8	2.01e-04	11	205	3	IPR027007
Domain	DHR_2	DOCK5 DOCK6 DOCK8	2.01e-04	11	205	3	PS51651
Domain	DHR_1	DOCK5 DOCK6 DOCK8	2.01e-04	11	205	3	PS51650
Domain	DHR-2	DOCK5 DOCK6 DOCK8	2.01e-04	11	205	3	PF06920
Domain	DOCK	DOCK5 DOCK6 DOCK8	2.01e-04	11	205	3	IPR026791
Domain	DOCK_C	DOCK5 DOCK6 DOCK8	2.01e-04	11	205	3	IPR010703
Domain	DOCK-C2	DOCK5 DOCK6 DOCK8	2.01e-04	11	205	3	PF14429
Domain	DHR-2	DOCK5 DOCK6 DOCK8	2.01e-04	11	205	3	IPR027357
Domain	EGF_LAM_2	USH2A LAMB4 LAMB1 LAMB2	3.09e-04	30	205	4	PS50027
Domain	EGF_LAM_1	USH2A LAMB4 LAMB1 LAMB2	3.09e-04	30	205	4	PS01248
Domain	Dynein_heavy_chain_D4_dom	DNAH6 DYNC1H1 DNAH7	4.34e-04	14	205	3	IPR024317
Domain	AAA_8	DNAH6 DYNC1H1 DNAH7	4.34e-04	14	205	3	PF12780
Domain	Sulfotransfer_1	SULT2A1 HS3ST3B1 HS3ST3A1 CHST3	6.31e-04	36	205	4	PF00685
Domain	Sulfotransferase_dom	SULT2A1 HS3ST3B1 HS3ST3A1 CHST3	6.31e-04	36	205	4	IPR000863
Domain	Argonaute_N	AGO2 AGO4	7.09e-04	4	205	2	IPR032474
Domain	Argonaute_Mid_dom	AGO2 AGO4	7.09e-04	4	205	2	IPR032473
Domain	ArgoL2	AGO2 AGO4	7.09e-04	4	205	2	IPR032472
Domain	ArgoN	AGO2 AGO4	7.09e-04	4	205	2	PF16486
Domain	ArgoMid	AGO2 AGO4	7.09e-04	4	205	2	PF16487
Domain	ArgoL2	AGO2 AGO4	7.09e-04	4	205	2	PF16488
Domain	DUF1785	AGO2 AGO4	1.17e-03	5	205	2	SM01163
Domain	DUF3398	DOCK6 DOCK8	1.75e-03	6	205	2	PF11878
Domain	ArgoL1	AGO2 AGO4	1.75e-03	6	205	2	PF08699
Domain	ArgoL1	AGO2 AGO4	1.75e-03	6	205	2	IPR014811
Domain	DOCK_C/D_N	DOCK6 DOCK8	1.75e-03	6	205	2	IPR021816
Domain	EGF_1	SCARF2 SLIT2 USH2A VWA2 FBLN7 LAMB4 FAT3 LAMB1 LAMB2	2.08e-03	255	205	9	PS00022
Domain	CbamoylP_synth_lsu-like_ATP-bd	CPS1 PC	2.43e-03	7	205	2	IPR005479
Domain	BC-like_N	CPS1 PC	2.43e-03	7	205	2	IPR005481
Domain	CPSase_L_D2	CPS1 PC	2.43e-03	7	205	2	PF02786
Domain	Biotin_carb_N	CPS1 PC	2.43e-03	7	205	2	PF00289
Domain	EGF-like_CS	SCARF2 SLIT2 ADAM17 VWA2 FBLN7 LAMB4 FAT3 LAMB1 LAMB2	2.43e-03	261	205	9	IPR013032
Pathway	REACTOME_INACTIVATION_OF_CDC42_AND_RAC1	SLIT2 SRGAP3 SRGAP2 ROBO1	9.76e-07	8	156	4	M27349
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	CDK18 SPAST MYO9A MAP3K3 CEP350 NF1 DENND1B PIK3C2A CGN KMT2A FOXO4 DOCK6 SORBS2 PPFIBP1 RICTOR SRGAP2 STK32C INPP5F DNAH7 AKT1S1 KIAA1671 SLF2 ANKRD17 MACF1 MTREX PC CSPP1 SNX2 EPB41L2	1.13e-13	861	213	29	36931259
Pubmed	Protein interaction network of the mammalian Hippo pathway reveals mechanisms of kinase-phosphatase interactions.	CDK18 TUBGCP2 NF1 PIK3C2A CGN DOCK6 SORBS2 DOCK8 PPFIBP1 RICTOR SRGAP2 INPP5F AKT1S1 KIAA1671 PRKDC MTREX CSPP1	2.84e-09	446	213	17	24255178
Pubmed	N-Terminomics for the Identification of In Vitro Substrates and Cleavage Site Specificity of the SARS-CoV-2 Main Protease.	SPAST MET CGN DYNC1H1 PTCD3 DHX16 SORBS2 PPFIBP1 NUMA1 NUP98 SRGAP2 MACF1 PRKDC PC SNX2	7.67e-09	360	213	15	33111431
Pubmed	Direct interaction between hnRNP-M and CDC5L/PLRG1 proteins affects alternative splice site choice.	DDX47 PRPF6 TUBGCP2 DOCK5 MLKL HSPA12A NF1 DYNC1H1 ARAP1 DOCK8 PPP2R1B INTS6 FANCI MACF1 PRKDC MTREX IK SNX2	2.43e-08	582	213	18	20467437
Pubmed	Defining the proximal interaction networks of Arf GTPases reveals a mechanism for the regulation of PLD1 and PI4KB.	SCARF2 RYR2 CEP350 DOCK5 MET INSM2 DYNC1H1 PRRC2B PTCD3 PPFIBP1 NUP98 GPRIN3 RICTOR SPECC1L DNAH7 KIAA1671 ROBO1 PRKDC PC EPB41L2	8.07e-08	777	213	20	35844135
Pubmed	Global genetic analysis in mice unveils central role for cilia in congenital heart disease.	SLIT2 BMP10 PKD1 CC2D2A CPLANE1 IFT88 ROBO1 MAPK7	1.99e-07	100	213	8	25807483
Pubmed	Inhibition of SRGAP2 function by its human-specific paralogs induces neoteny during spine maturation.	SRGAP2C SRGAP2 SRGAP2B	2.27e-07	3	213	3	22559944
Pubmed	Type 1 and type 3 ryanodine receptors are selectively involved in muscarinic antinociception in mice: an antisense study.	RYR1 RYR2 RYR3	2.27e-07	3	213	3	18403125
Pubmed	Heterogeneous gene expression and functional activity of ryanodine receptors in resistance and conduit pulmonary as well as mesenteric artery smooth muscle cells.	RYR1 RYR2 RYR3	2.27e-07	3	213	3	18434746
Pubmed	SPRY domains in ryanodine receptors (Ca(2+)-release channels).	RYR1 RYR2 RYR3	2.27e-07	3	213	3	9204703
Pubmed	Ryanodine receptors are expressed in epidermal keratinocytes and associated with keratinocyte differentiation and epidermal permeability barrier homeostasis.	RYR1 RYR2 RYR3	2.27e-07	3	213	3	21881589
Pubmed	Isoform-dependent formation of heteromeric Ca2+ release channels (ryanodine receptors).	RYR1 RYR2 RYR3	2.27e-07	3	213	3	12213830
Pubmed	Calcineurin upregulates local Ca(2+) signaling through ryanodine receptor-1 in airway smooth muscle cells.	RYR1 RYR2 RYR3	2.27e-07	3	213	3	25239916
Pubmed	Identification of mutations in the cardiac ryanodine receptor gene in families affected with arrhythmogenic right ventricular cardiomyopathy type 2 (ARVD2).	RYR1 RYR2 RYR3	2.27e-07	3	213	3	11159936
Pubmed	Chromosomal localization of murine ryanodine receptor genes RYR1, RYR2, and RYR3 by in situ hybridization.	RYR1 RYR2 RYR3	2.27e-07	3	213	3	7959768
Pubmed	Regulation of mouse egg activation: presence of ryanodine receptors and effects of microinjected ryanodine and cyclic ADP ribose on uninseminated and inseminated eggs.	RYR1 RYR2 RYR3	2.27e-07	3	213	3	7635066
Pubmed	The ryanodine receptor/calcium channel genes are widely and differentially expressed in murine brain and peripheral tissues.	RYR1 RYR2 RYR3	2.27e-07	3	213	3	7876312
Pubmed	Bidirectional coupling between ryanodine receptors and Ca2+ release-activated Ca2+ (CRAC) channel machinery sustains store-operated Ca2+ entry in human T lymphocytes.	RYR1 RYR2 RYR3	2.27e-07	3	213	3	22948152
Pubmed	Developmental changes in expression of the three ryanodine receptor mRNAs in the mouse brain.	RYR1 RYR2 RYR3	2.27e-07	3	213	3	10788707
Pubmed	Ca(2+)-induced Ca2+ release in myocytes from dyspedic mice lacking the type-1 ryanodine receptor.	RYR1 RYR2 RYR3	2.27e-07	3	213	3	7621815
Pubmed	Molecular identification of the ryanodine receptor pore-forming segment.	RYR1 RYR2 RYR3	2.27e-07	3	213	3	10473538
Pubmed	Expression of the ryanodine receptor type 3 calcium release channel during development and differentiation of mammalian skeletal muscle cells.	RYR1 RYR2 RYR3	2.27e-07	3	213	3	9242641
Pubmed	A gene-specific cerebral types 1, 2, and 3 RyR protein knockdown induces an antidepressant-like effect in mice.	RYR1 RYR2 RYR3	2.27e-07	3	213	3	18643873
Pubmed	The organization of proteins in the human red blood cell membrane. A review.	RYR1 RYR2 RYR3	2.27e-07	3	213	3	4600883
Pubmed	Comprehensive proteomic analysis of interphase and mitotic 14-3-3-binding proteins.	CDK18 CGN DYNC1H1 SORBS2 PPFIBP1 NUMA1 SRGAP2 CPS1 AKT1S1 PRKDC	3.06e-07	190	213	10	15161933
Pubmed	A human MAP kinase interactome.	MYO9A MAP3K3 CEP350 CPLANE1 NUP98 LAMB1 LAMB2 SPECC1L STK32C ANKRD17 MACF1 ROBO1 PRKDC MAPK7 EPB41L2	3.80e-07	486	213	15	20936779
Pubmed	Identifying biological pathways that underlie primordial short stature using network analysis.	DDX47 CASP14 PRPF6 CEP350 SLIT2 NF1 CGN DYNC1H1 DHX16 NUMA1 NUP98 LAMB2 SPECC1L KIAA1671 RPAP1 UBA6 MACF1 PRKDC MTREX IK SNX2 EPB41L2	3.95e-07	1024	213	22	24711643
Pubmed	Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.	GIPC1 AGO2 GATAD2B HIRA NF1 CAMKV SRGAP3 DYNC1H1 PRRC2B SORBS2 NUMA1 SPATA20 SRGAP2 GRIN2A SPECC1L GRM2 UBA6 ANKRD17 MACF1 CTNNA2 EPB41L2	5.79e-07	963	213	21	28671696
Pubmed	Reciprocal interaction between SIRT6 and APC/C regulates genomic stability.	DDX47 DDX59 PRPF6 RPS6KC1 NF1 ANAPC4 NUMA1 NUP98 GPATCH2 AMBRA1 RICTOR PPP2R1B ANKRD17 MTREX	6.55e-07	440	213	14	34244565
Pubmed	Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.	PRPF6 NF1 CGN KMT2A DYNC1H1 PRRC2B PTCD3 DHX16 NUMA1 NUP98 FANCI ANKRD17 MACF1 PRKDC MTREX IK EPB41L2	6.75e-07	653	213	17	22586326
Pubmed	Genetic link between renal birth defects and congenital heart disease.	SLIT2 BMP10 PKD1 CC2D2A ROBO1	7.20e-07	28	213	5	27002738
Pubmed	KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.	ILDR2 AGO2 MYO9A HSPA12A NF1 CAMKV SRGAP3 HECW2 KMT2A DNAH6 DYNC1H1 PRRC2B PTCD3 SORBS2 DOCK8 SRGAP2 GRIN2A SPECC1L GRM2 WDR37 MACF1 CTNNA2 PC SNX2 EPB41L2 SCAI	8.05e-07	1431	213	26	37142655
Pubmed	Evolution of human-specific neural SRGAP2 genes by incomplete segmental duplication.	SRGAP2C SRGAP2 SRGAP2B	9.02e-07	4	213	3	22559943
Pubmed	Ryanodine receptor calcium release channels: lessons from structure-function studies.	RYR1 RYR2 RYR3	9.02e-07	4	213	3	23413940
Pubmed	Partial cloning and differential expression of ryanodine receptor/calcium-release channel genes in human tissues including the hippocampus and cerebellum.	RYR1 RYR2 RYR3	9.02e-07	4	213	3	9607712
Pubmed	Conserved and divergent functions of Nfix in skeletal muscle development during vertebrate evolution.	RYR1 RYR2 RYR3	9.02e-07	4	213	3	23482488
Pubmed	A glutathione deficit alters dopamine modulation of L-type calcium channels via D2 and ryanodine receptors in neurons.	RYR1 RYR2 RYR3	9.02e-07	4	213	3	18206662
Pubmed	Nuclear Mitotic Apparatus (NuMA) Interacts with and Regulates Astrin at the Mitotic Spindle.	DYNC1H1 NUMA1 SPAG5	9.02e-07	4	213	3	27462074
Pubmed	Requirement for the ryanodine receptor type 3 for efficient contraction in neonatal skeletal muscles.	RYR1 RYR2 RYR3	9.02e-07	4	213	3	9384575
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	RYR1 HIRA TNRC18 ZBED4 CANT1 PKD1 CACNA1H DOCK6 DYNC1H1 PRRC2B ARAP1 B4GALNT4 LAMB2 AMBRA1 SPATA20 SRGAP2 STK32C RPAP1 FANCI PRKDC PC CYB5R2	1.39e-06	1105	213	22	35748872
Pubmed	The HECT type ubiquitin ligase NEDL2 is degraded by anaphase-promoting complex/cyclosome (APC/C)-Cdh1, and its tight regulation maintains the metaphase to anaphase transition.	GIPC1 SPAST TUBGCP2 HECW2 KMT2A CDT1 ANAPC4 LAMB1 SPAG5 MACF1 PC	1.47e-06	281	213	11	24163370
Pubmed	Synaptic GAP and GEF Complexes Cluster Proteins Essential for GTP Signaling.	NF1 SRGAP3 DYNC1H1 SORBS2 SRGAP2 GRIN2A SPECC1L GRM2 MACF1 CTNNA2 EPB41L2	1.47e-06	281	213	11	28706196
Pubmed	Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.	DDX47 AGO2 TUBGCP2 GATAD2B MLKL SLIT2 ADAM17 PRRC2B ANAPC4 PTCD3 FAT3 GPATCH2 LAMB1 AMBRA1 RICTOR WDR37 KIAA1671 INTS6 SAP30BP CAPRIN2 ANKRD17 MACF1	1.63e-06	1116	213	22	31753913
Pubmed	Targeting RICTOR Sensitizes SMAD4-Negative Colon Cancer to Irinotecan.	CYP24A1 DOCK6 ARAP1 PPFIBP1 LAMB2 RICTOR SRGAP2 DNAJC2 UBA6	2.12e-06	183	213	9	31932471
Pubmed	Protein kinase C-epsilon regulates local calcium signaling in airway smooth muscle cells.	RYR1 RYR2 RYR3	2.24e-06	5	213	3	19011160
Pubmed	Presenilins regulate calcium homeostasis and presynaptic function via ryanodine receptors in hippocampal neurons.	RYR1 RYR2 RYR3	2.24e-06	5	213	3	23918386
Pubmed	Ex vivo Quantitative Proteomic Analysis of Serotonin Transporter Interactome: Network Impact of the SERT Ala56 Coding Variant.	CDK18 AGO2 MYO9A TUBGCP2 NF1 SRGAP3 PTCD3 SORBS2 GRIN2A TPH2 MACF1 PC SCAI	2.90e-06	430	213	13	32581705
Pubmed	Multiplexed kinase interactome profiling quantifies cellular network activity and plasticity.	AGO2 STK17B ANKRD36C GATAD2B MAP3K3 MLKL MET NF1 AGO4 KMT2A CPLANE1 ANAPC4 RBL2 PPFIBP1 GPATCH2 RBFOX1 SAP30BP MAPK7 SCAI	3.84e-06	910	213	19	36736316
Pubmed	Membrane depolarization causes a direct activation of G protein-coupled receptors leading to local Ca2+ release in smooth muscle.	RYR1 RYR2 RYR3	4.47e-06	6	213	3	19549818
Pubmed	Essential Roles of Intracellular Calcium Release Channels in Muscle, Brain, Metabolism, and Aging.	RYR1 RYR2 RYR3	4.47e-06	6	213	3	25966694
Pubmed	A calcium-induced calcium release mechanism supports luteinizing hormone-induced testosterone secretion in mouse Leydig cells.	RYR1 RYR2 RYR3	4.47e-06	6	213	3	20519450
Pubmed	Signal transduction in neuronal migration: roles of GTPase activating proteins and the small GTPase Cdc42 in the Slit-Robo pathway.	SRGAP3 SRGAP2 ROBO1	4.47e-06	6	213	3	11672528
Pubmed	Rectification of muscle and nerve deficits in paralyzed ryanodine receptor type 1 mutant embryos.	RYR1 RYR2 RYR3	4.47e-06	6	213	3	26025922
Pubmed	Roles of I(f) and intracellular Ca2+ release in spontaneous activity of ventricular cardiomyocytes during murine embryonic development.	RYR1 RYR2 RYR3	4.47e-06	6	213	3	23463619
Pubmed	FKBP12.6 and cADPR regulation of Ca2+ release in smooth muscle cells.	RYR1 RYR2 RYR3	4.47e-06	6	213	3	14592808
Pubmed	HIV-1 Tat activates neuronal ryanodine receptors with rapid induction of the unfolded protein response and mitochondrial hyperpolarization.	RYR1 RYR2 RYR3	4.47e-06	6	213	3	19009018
Pubmed	IP3Rs are sufficient for dendritic cell Ca2+ signaling in the absence of RyR1.	RYR1 RYR2 RYR3	4.47e-06	6	213	3	16844763
Pubmed	Oct4 links multiple epigenetic pathways to the pluripotency network.	DDX47 GATAD2B DYNC1H1 PRRC2B NUMA1 LAMB1 JMJD1C SAP30BP ANKRD17	4.95e-06	203	213	9	22083510
Pubmed	Voltage-dependent conformational changes of Kv1.3 channels activate cell proliferation.	MYO9A RYR1 CGN KMT2A DNHD1 SPECC1L TLR3 CAPRIN2 ANKRD17	6.03e-06	208	213	9	33230847
Pubmed	Large-scale characterization of HeLa cell nuclear phosphoproteins.	GATAD2B NF1 ZBTB40 KMT2A CDT1 DHX16 SORBS2 NUMA1 NUP98 RICTOR AKT1S1 SMTN RPAP1 ANKRD17 PRKDC SNX2 EPB41L2	6.56e-06	774	213	17	15302935
Pubmed	Human immunodeficiency virus-1 Tat activates calpain proteases via the ryanodine receptor to enhance surface dopamine transporter levels and increase transporter-specific uptake and Vmax.	RYR1 RYR2 RYR3	7.79e-06	7	213	3	20962236
Pubmed	Evidence for a role of srGAP3 in the positioning of commissural axons within the ventrolateral funiculus of the mouse spinal cord.	SRGAP3 SRGAP2 ROBO1	7.79e-06	7	213	3	21655271
Pubmed	Developmental expression of the calcium release channels during early neurogenesis of the mouse cerebral cortex.	RYR1 RYR2 RYR3	7.79e-06	7	213	3	11860456
Pubmed	Neuron-specific protein network mapping of autism risk genes identifies shared biological mechanisms and disease-relevant pathologies.	SPAST GATAD2B RYR2 RPS6KC1 MET HSPA12A TNRC18 NF1 CAMKV SRGAP3 SCN1A PTCD3 SORBS2 RICTOR GRIN2A AKR7L AKR7A3 MACF1 CTNNA2 PC EPB41L2	7.93e-06	1139	213	21	36417873
Pubmed	SRCAP complex promotes lung cancer progression by reprograming the oncogenic transcription of Hippo-YAP/TAZ signaling pathway.	AGO2 CGN KMT2A DYNC1H1 PRRC2B NUMA1 SPECC1L JMJD1C KIAA1671 SAP30BP PRKDC IK PC SNX2	8.45e-06	549	213	14	38280479
Pubmed	Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.	DDX47 AGO2 CASP14 MYO9A PRPF6 HIRA NF1 PIK3C2A ALOX12B DYNC1H1 PTCD3 DHX16 NUMA1 AMBRA1 RICTOR SMTN FANCI ANKRD17 MACF1 PRKDC MTREX IK EPB41L2	1.07e-05	1353	213	23	29467282
Pubmed	LGALS3BP regulates centriole biogenesis and centrosome hypertrophy in cancer cells.	AGO2 TUBGCP2 CEP350 PIK3C2A KMT2A ANAPC4 PTCD3 RBL2 PPFIBP1 SRGAP2 PPP2R1B FANCI ANKRD17 PRKDC CTNNA2	1.07e-05	639	213	15	23443559
Pubmed	Sequential docking, molecular differentiation, and positioning of T-Tubule/SR junctions in developing mouse skeletal muscle.	RYR1 RYR2 RYR3	1.24e-05	8	213	3	11784029
Pubmed	Roles of IP3R and RyR Ca2+ channels in endoplasmic reticulum stress and beta-cell death.	RYR1 RYR2 RYR3	1.24e-05	8	213	3	19033399
Pubmed	Neuromuscular synaptic patterning requires the function of skeletal muscle dihydropyridine receptors.	MNX1 RYR1 RYR3	1.24e-05	8	213	3	21441923
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	KDM4C TMEM200A MYSM1 GATAD2B LAPTM5 CEP350 TNRC18 CGN PPFIBP1 GPRIN3 RICTOR JMJD1C MACF1	1.25e-05	493	213	13	15368895
Pubmed	Systems analysis of RhoGEF and RhoGAP regulatory proteins reveals spatially organized RAC1 signalling from integrin adhesions.	GIPC1 CASP14 MYO9A PRPF6 DOCK5 SRGAP3 CGN KMT2A DOCK6 ARAP1 DOCK8 NUMA1 NUP98 SRGAP2 KIAA1671 FANCI ROBO1 EPB41L2	1.57e-05	916	213	18	32203420
Pubmed	Proteomic analysis reveals GIT1 as a novel mTOR complex component critical for mediating astrocyte survival.	NF1 RICTOR AKT1S1	1.85e-05	9	213	3	27340174
Pubmed	Transcriptome characterization elucidates signaling networks that control human ES cell growth and differentiation.	CYP24A1 MAP3K3 TNRC18 NF1 DGUOK CGN PKD1 ADAM17 PRRC2B B4GALNT4 SORBS2 FAT3 CASP4 LAMB2 SPECC1L INPP5F CPS1 NSMF AKR7L FANCI PC	2.07e-05	1215	213	21	15146197
Pubmed	A deep proteomics perspective on CRM1-mediated nuclear export and nucleocytoplasmic partitioning.	DDX47 LIN9 MAP3K3 CEP350 DENND1B BCL10 CDT1 DOCK6 ANAPC4 DHX16 GPATCH2 RICTOR BLZF1 AKT1S1 SHROOM1 RPAP1 MTREX IK MAPK7	2.41e-05	1038	213	19	26673895
Pubmed	Slit/Robo signals prevent spinal motor neuron emigration by organizing the spinal cord basement membrane.	MNX1 SLIT2 ROBO1	2.63e-05	10	213	3	31356769
Pubmed	Systematic analysis of human protein complexes identifies chromosome segregation proteins.	PRPF6 TUBGCP2 LIN9 CEP350 DYNC1H1 PRRC2B ARAP1 ANAPC4 PTCD3 DHX16 NUMA1 NUP98 LAMB1 AMBRA1 CPS1 SPAG5 SMTN PPP2R1B PRKDC DCAF4	3.20e-05	1155	213	20	20360068
Pubmed	Motor axon exit from the mammalian spinal cord is controlled by the homeodomain protein Nkx2.9 via Robo-Slit signaling.	MNX1 SLIT2 ROBO1	3.60e-05	11	213	3	22399681
Pubmed	Acid-sensing ion channel 3, but not capsaicin receptor TRPV1, plays a protective role in isoproterenol-induced myocardial ischemia in mice.	ASIC3 TRPV1	3.73e-05	2	213	2	21127383
Pubmed	SLIT2 attenuation during lung cancer progression deregulates beta-catenin and E-cadherin and associates with poor prognosis.	SLIT2 ROBO1	3.73e-05	2	213	2	20068157
Pubmed	Endothelial cilia are fluid shear sensors that regulate calcium signaling and nitric oxide production through polycystin-1.	PKD1 IFT88	3.73e-05	2	213	2	18285569
Pubmed	Silencing of miRNA-218 promotes migration and invasion of breast cancer via Slit2-Robo1 pathway.	SLIT2 ROBO1	3.73e-05	2	213	2	22898079
Pubmed	TRPV1 in brain is involved in acetaminophen-induced antinociception.	FAAH TRPV1	3.73e-05	2	213	2	20862299
Pubmed	Contractile impairment and structural alterations of skeletal muscles from knockout mice lacking type 1 and type 3 ryanodine receptors.	RYR1 RYR3	3.73e-05	2	213	2	9489997
Pubmed	Ryanodine receptor oligomeric interaction: identification of a putative binding region.	RYR1 RYR2	3.73e-05	2	213	2	14722100
Pubmed	Structural and functional interactions within ryanodine receptor.	RYR1 RYR2	3.73e-05	2	213	2	26009179
Pubmed	Expression of the axon guidance factor Slit2 and its receptor Robo1 in patients with Hirschsprung disease: An observational study.	SLIT2 ROBO1	3.73e-05	2	213	2	34414975
Pubmed	The C-terminal region of laminin beta chains modulates the integrin binding affinities of laminins.	LAMB1 LAMB2	3.73e-05	2	213	2	19147489
Pubmed	Slit2‑Robo1 signaling promotes the adhesion, invasion and migration of tongue carcinoma cells via upregulating matrix metalloproteinases 2 and 9, and downregulating E‑cadherin.	SLIT2 ROBO1	3.73e-05	2	213	2	27431199
Pubmed	Tissue-specific alternative splicing of mouse brain type ryanodine receptor/calcium release channel mRNA.	RYR2 RYR3	3.73e-05	2	213	2	8898078
Pubmed	Expression of cation exchanger NHE and anion exchanger AE isoforms in primary human bone-derived osteoblasts.	SLC4A2 SLC9A3	3.73e-05	2	213	2	10452823
Pubmed	TRPV1 Responses in the Cerebellum Lobules VI, VII, VIII Using Electroacupuncture Treatment for Chronic Pain and Depression Comorbidity in a Murine Model.	ASIC3 TRPV1	3.73e-05	2	213	2	34068557
Pubmed	The mouse sino-atrial node expresses both the type 2 and type 3 Ca(2+) release channels/ryanodine receptors.	RYR2 RYR3	3.73e-05	2	213	2	14550562
Pubmed	SLIT2/ROBO1 axis contributes to the Warburg effect in osteosarcoma through activation of SRC/ERK/c-MYC/PFKFB2 pathway.	SLIT2 ROBO1	3.73e-05	2	213	2	29523788
Pubmed	Global analysis of AGO2-bound RNAs reveals that miRNAs induce cleavage of target RNAs with limited complementarity.	AGO2 PRKDC	3.73e-05	2	213	2	29031931
Pubmed	Structural insights into the Slit-Robo complex.	SLIT2 ROBO1	3.73e-05	2	213	2	17848514
Pubmed	Ryanodine receptors in human pancreatic beta cells: localization and effects on insulin secretion.	RYR1 RYR2	3.73e-05	2	213	2	15033925
Pubmed	Forced expression of laminin beta1 in podocytes prevents nephrotic syndrome in mice lacking laminin beta2, a model for Pierson syndrome.	LAMB1 LAMB2	3.73e-05	2	213	2	21876163
Pubmed	Ductular reaction promotes intrahepatic angiogenesis through Slit2-Roundabout 1 signaling.	SLIT2 ROBO1	3.73e-05	2	213	2	34490644
Pubmed	Expression and functional activity of ryanodine receptors (RyRs) during skeletal muscle development.	RYR1 RYR3	3.73e-05	2	213	2	17118445
Interaction	YWHAH interactions	CDK18 SPAST MYO9A PRPF6 MAP3K3 CEP350 NF1 DENND1B PIK3C2A CGN KMT2A CC2D2A FOXO4 DOCK6 SORBS2 PPFIBP1 RICTOR SRGAP2 SPECC1L INPP5F WDR37 DNAH7 AKT1S1 KIAA1671 SHROOM1 CDCA7 SLF2 ANKRD17 MACF1 MTREX MAPK7 CSPP1 SNX2 EPB41L2	1.23e-08	1102	210	34	int:YWHAH
Interaction	YWHAQ interactions	CDK18 MYO9A MAP3K3 CEP350 NF1 DENND1B PIK3C2A CGN KMT2A VWA2 DYNC1H1 SORBS2 PPFIBP1 NUMA1 RICTOR SRGAP2 SPECC1L INPP5F CPS1 GRM2 WDR37 DNAH7 AKT1S1 KIAA1671 SHROOM1 CDCA7 ANKRD17 MACF1 PRKDC MTREX PC SNX2 EPB41L2	5.92e-08	1118	210	33	int:YWHAQ
Interaction	YWHAG interactions	CDK18 SPAST MYO9A MAP3K3 CEP350 NF1 DENND1B PIK3C2A CGN KMT2A FOXO4 LTB4R DYNC1H1 SORBS2 PPFIBP1 RICTOR SRGAP2 SPECC1L INPP5F WDR37 DNAH7 AKT1S1 KIAA1671 SHROOM1 CDCA7 ANKRD17 MACF1 PRKDC MTREX MAPK7 CSPP1 SNX2 EPB41L2	7.33e-07	1248	210	33	int:YWHAG
Interaction	YWHAB interactions	CDK18 MYO9A PRPF6 MAP3K3 CEP350 NF1 DENND1B PIK3C2A CGN KMT2A FOXO4 VWA2 DYNC1H1 SORBS2 PPFIBP1 RICTOR SRGAP2 INPP5F WDR37 AKT1S1 KIAA1671 SHROOM1 ANKRD17 MACF1 MTREX MAPK7 EPB41L2	7.37e-06	1014	210	27	int:YWHAB
Cytoband	2q32.3	STK17B HECW2 DNAH7	2.10e-05	12	213	3	2q32.3
Cytoband	7q31	MET TAS2R16 LAMB4	2.65e-04	27	213	3	7q31
GeneFamily	Ryanodine receptors\|Protein phosphatase 1 regulatory subunits	RYR1 RYR2 RYR3	3.63e-07	3	130	3	287
GeneFamily	Rho GTPase activating proteins\|F-BAR domain containing	SRGAP2C SRGAP3 SRGAP2 SRGAP2B	2.03e-05	23	130	4	1288
GeneFamily	Laminin subunits	LAMB4 LAMB1 LAMB2	7.62e-05	12	130	3	626
GeneFamily	Argonaute/PIWI family	AGO2 AGO4	1.40e-03	8	130	2	408
GeneFamily	Ankyrin repeat domain containing	ANKMY1 ANKRD36C GABPB2 ARAP1 TRPV1 ANKRD17 GABPB1	1.85e-03	242	130	7	403
GeneFamily	Sulfotransferases, membrane bound	HS3ST3B1 HS3ST3A1 CHST3	2.36e-03	37	130	3	763
CoexpressionAtlas	dev gonad_e13.5_F_VascAssocMesenchStromOvary_MafB_k-means-cluster#1_top-relative-expression-ranked_1000	DCBLD1 RYR2 SRGAP3 ATP13A3 HS3ST3A1 SORBS2 COL12A1 KCNG3 SLF2 RBFOX1	5.53e-06	166	207	10	gudmap_dev gonad_e13.5_F_VascAssocMesenchStromOvary_MafB_k1_1000
CoexpressionAtlas	DevelopingGonad_e16.5_ovary_emap-9563_top-relative-expression-ranked_1000	ILDR2 AGO2 MYO9A CLTRN MYSM1 RYR1 RYR2 SLIT2 DENND1B CGN CPLANE1 SORBS2 HSF2BP INPP5F DNAH7 CAPRIN2 UBA6 ANKRD17 UGGT2 CSPP1 EPB41L2 SCAI	1.12e-05	795	207	22	gudmap_developingGonad_e16.5_ovary_1000
CoexpressionAtlas	dev gonad_e12.5_F_SupCellPrec_Sry_top-relative-expression-ranked_500	MYO9A DCBLD1 RYR2 TNRC18 DENND1B SRGAP3 CGN ATP13A3 HS3ST3A1 SORBS2 COL12A1 KCNG3 DNAH7 INTS6 SLF2	1.44e-05	414	207	15	gudmap_dev gonad_e12.5_F_SupCellPrec_Sry_500
CoexpressionAtlas	DevelopingLowerUrinaryTract_P1_bladder_J_emap-30374_k-means-cluster#1_top-relative-expression-ranked_1000	RYR2 CEP350 PIK3C2A ATP13A3 FAM13C PI16 DOCK8 MEDAG MYOCD	1.61e-05	149	207	9	gudmap_developingLowerUrinaryTract_P1_bladder_J_1000_k1
CoexpressionAtlas	dev gonad_e13.5_F_VascAssocMesenchStromOvary_MafB_k-means-cluster#2_top-relative-expression-ranked_500	DCBLD1 RYR2 SRGAP3 HS3ST3A1 SORBS2 COL12A1 SLF2	3.78e-05	94	207	7	gudmap_dev gonad_e13.5_F_VascAssocMesenchStromOvary_MafB_k2_500
CoexpressionAtlas	DevelopingGonad_e18.5_ovary_emap-12283_k-means-cluster#3_top-relative-expression-ranked_500	ILDR2 CLTRN MYSM1 GABPB2 CPLANE1 EPB41L2 SCAI	4.62e-05	97	207	7	gudmap_developingGonad_e18.5_ovary_500_k3
CoexpressionAtlas	DevelopingGonad_e16.5_epididymis_emap-29702_top-relative-expression-ranked_500	ILDR2 AGO2 CLTRN MYSM1 SLIT2 TNRC18 CPLANE1 MGAM FAT3 WDR37 MYOCD CSPP1 EPB41L2 SCAI	4.80e-05	406	207	14	gudmap_developingGonad_e16.5_epididymis_500
CoexpressionAtlas	dev gonad_e13.5_F_SupCellPrec_Sry_top-relative-expression-ranked_500	MYO9A DCBLD1 RYR2 DENND1B SRGAP3 CGN ATP13A3 HS3ST3A1 SORBS2 COL12A1 KCNG3 INTS6 SLF2 CAPRIN2	7.26e-05	422	207	14	gudmap_dev gonad_e13.5_F_SupCellPrec_Sry_500
CoexpressionAtlas	DevelopingGonad_e14.5_ ovary_emap-6699_k-means-cluster#3_top-relative-expression-ranked_1000	MYO9A CLTRN MYSM1 SLIT2 GABPB2 CPLANE1 RICTOR JMJD1C EPB41L2 SCAI	7.59e-05	225	207	10	gudmap_developingGonad_e14.5_ ovary_1000_k3
CoexpressionAtlas	DevelopingGonad_e18.5_ovary_emap-12283_top-relative-expression-ranked_1000	ILDR2 CLTRN ESRP1 MYSM1 RYR2 SLIT2 DENND1B GABPB2 CGN CPLANE1 SORBS2 HSF2BP WDR37 DNAH7 CAPRIN2 UBA6 UGGT2 CSPP1 EPB41L2 SCAI	7.94e-05	778	207	20	gudmap_developingGonad_e18.5_ovary_1000
CoexpressionAtlas	DevelopingGonad_e16.5_ovary_emap-9563_k-means-cluster#5_top-relative-expression-ranked_500	ILDR2 MYSM1 SLIT2 CPLANE1 SORBS2 EPB41L2 SCAI	9.72e-05	109	207	7	gudmap_developingGonad_e16.5_ovary_500_k5
CoexpressionAtlas	DevelopingGonad_e14.5_ epididymis_emap-29141_k-means-cluster#1_top-relative-expression-ranked_100	CLTRN MYSM1 SLIT2 EPB41L2 SCAI	1.02e-04	48	207	5	gudmap_developingGonad_e14.5_ epididymis_100_k1
CoexpressionAtlas	dev gonad_e13.5_F_SupCellPrec_Sry_k-means-cluster#3_top-relative-expression-ranked_1000	DCBLD1 RYR2 SRGAP3 CGN ATP13A3 SORBS2 COL12A1 PHOSPHO2 KCNG3 SLF2 RBFOX1	1.04e-04	281	207	11	gudmap_dev gonad_e13.5_F_SupCellPrec_Sry_k3_1000
CoexpressionAtlas	DevelopingKidney_e15.5_ureter tip_flank cortic collct_emap-27752_top-relative-expression-ranked_1000	ESRP1 DCBLD1 MYSM1 CEP350 SLIT2 MET DENND1B PIK3C2A ATP13A3 HS3ST3B1 CPLANE1 HS3ST3A1 VWA2 MGAM B4GALNT4 SORBS2 PPFIBP1 LAMB1 SRGAP2 TLR3	1.18e-04	801	207	20	gudmap_developingKidney_e15.5_ureter tip_1000_flank cortic collct
CoexpressionAtlas	DevelopingGonad_P2_ovary_emap-30224_k-means-cluster#5_top-relative-expression-ranked_1000	ILDR2 CLTRN MYSM1 DENND1B CPLANE1 LAMB1 EPB41L2 SCAI	1.20e-04	151	207	8	gudmap_developingGonad_P2_ovary_1000_k5
CoexpressionAtlas	DevelopingGonad_e14.5_ epididymis_emap-29141_top-relative-expression-ranked_100	CLTRN MYSM1 SLIT2 MGAM EPB41L2 SCAI	1.72e-04	84	207	6	gudmap_developingGonad_e14.5_ epididymis_100
CoexpressionAtlas	DevelopingGonad_e18.5_epididymis_emap-13166_top-relative-expression-ranked_500	ILDR2 AGO2 CLTRN MYSM1 SLIT2 MGAM SORBS2 FAT3 MEDAG MYOCD CSPP1 EPB41L2 SCAI	1.78e-04	404	207	13	gudmap_developingGonad_e18.5_epididymis_500
CoexpressionAtlas	dev gonad_e12.5_F_VasAssMesen_MafB_k-means-cluster#4_top-relative-expression-ranked_1000	MYO9A DCBLD1 RYR2 DENND1B CGN ATP13A3 HS3ST3A1 SORBS2 COL12A1 AKT1S1 SLF2	1.90e-04	301	207	11	gudmap_dev gonad_e12.5_F_VasAssMesen_MafB_k4_1000
CoexpressionAtlas	DevelopingGonad_e14.5_ ovary_emap-6699_top-relative-expression-ranked_1000	ILDR2 MYO9A STK17B CLTRN MYSM1 RYR2 SLIT2 GABPB2 HS3ST3B1 CPLANE1 HSF2BP RICTOR JMJD1C TPH2 UBA6 ANKRD17 CSPP1 EPB41L2 SCAI	2.24e-04	776	207	19	gudmap_developingGonad_e14.5_ ovary_1000
CoexpressionAtlas	DevelopingGonad_e18.5_ovary_emap-12283_k-means-cluster#2_top-relative-expression-ranked_1000	ILDR2 CLTRN MYSM1 SLIT2 GABPB2 CPLANE1 SORBS2 EPB41L2 SCAI	2.28e-04	210	207	9	gudmap_developingGonad_e18.5_ovary_1000_k2
CoexpressionAtlas	DevelopingGonad_e16.5_ovary_emap-9563_k-means-cluster#5_top-relative-expression-ranked_1000	MYO9A RYR1 RYR2 DENND1B CGN INPP5F DNAH7 CAPRIN2 UGGT2	3.10e-04	219	207	9	gudmap_developingGonad_e16.5_ovary_1000_k5
CoexpressionAtlas	DevelopingGonad_e14.5_ epididymis_emap-29141_top-relative-expression-ranked_1000	ILDR2 AGO2 CLTRN MYSM1 LAPTM5 SLIT2 TNRC18 GABPB2 CPLANE1 ARAP1 MGAM FAT3 LAMB1 INPP5F WDR37 JMJD1C CSPP1 EPB41L2 SCAI	3.33e-04	801	207	19	gudmap_developingGonad_e14.5_ epididymis_1000
CoexpressionAtlas	dev gonad_e12.5_F_SupCellPrec_Sry_top-relative-expression-ranked_1000	MYO9A DCBLD1 RYR2 TNRC18 DENND1B PIK3C2A SRGAP3 CGN SRL ATP13A3 HS3ST3A1 SORBS2 COL12A1 KCNG3 DNAH7 INTS6 SLF2 CAPRIN2 CSPP1	3.44e-04	803	207	19	gudmap_dev gonad_e12.5_F_SupCellPrec_Sry_1000
CoexpressionAtlas	dev gonad_e13.5_F_SupCellPrec_Sry_top-relative-expression-ranked_1000	MYO9A DCBLD1 RYR2 DENND1B SRGAP3 CGN CC2D2A ATP13A3 HS3ST3A1 SORBS2 COL12A1 PHOSPHO2 INPP5F KCNG3 DNAH7 INTS6 SLF2 RBFOX1 CAPRIN2	3.49e-04	804	207	19	gudmap_dev gonad_e13.5_F_SupCellPrec_Sry_1000
CoexpressionAtlas	dev gonad_e13.5_F_VascAssocMesenchStromOvary_MafB_top-relative-expression-ranked_1000	MYO9A DCBLD1 RYR2 CEP350 SLIT2 SRGAP3 CGN ATP13A3 HS3ST3A1 SORBS2 COL12A1 FAT3 KCNG3 INTS6 SLF2 RBFOX1 CAPRIN2 SCAI	3.56e-04	740	207	18	gudmap_dev gonad_e13.5_F_VascAssocMesenchStromOvary_MafB_1000
CoexpressionAtlas	DevelopingGonad_P2_epididymis_emap-30199_k-means-cluster#2_top-relative-expression-ranked_500	MYSM1 GABPB2 MGAM SORBS2 FAT3 EPB41L2 SCAI	3.82e-04	136	207	7	gudmap_developingGonad_P2_epididymis_500_k2
CoexpressionAtlas	DevelopingGonad_e14.5_ epididymis_emap-29141_k-means-cluster#3_top-relative-expression-ranked_1000	ILDR2 MYSM1 SLIT2 GABPB2 CPLANE1 LAMB1 INPP5F JMJD1C EPB41L2 SCAI	3.85e-04	275	207	10	gudmap_developingGonad_e14.5_ epididymis_1000_k3
CoexpressionAtlas	DevelopingGonad_P2_ovary_emap-30224_k-means-cluster#2_top-relative-expression-ranked_500	ILDR2 MYSM1 CPLANE1 EPB41L2 SCAI	4.31e-04	65	207	5	gudmap_developingGonad_P2_ovary_500_k2
ToppCell	ILEUM-inflamed-(3)_MNP-(3)_moDC\|(3)_MNP / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)	STK17B DOCK5 SRGAP2C SRGAP3 ADAM17 GPRIN3 RICTOR JMJD1C HAVCR2 SRGAP2B EPB41L2	1.81e-09	187	213	11	0099def970fbc828756fbf853eca2ce77b8cd342
ToppCell	Posterior_cortex-Neuronal-Excitatory-eN1(Slc17a7)-eN1_1-Bcl6\|Posterior_cortex / BrainAtlas - Mouse McCarroll V32	TMEM200A RYR1 RYR3 KIF9 INSM2 CACNA1H DNAH6 ALOX12B GPRIN3 KCNG3	2.02e-09	144	213	10	08005be9e3367f78ef27e125d9cce5ca53f4bd2d
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Renal_corpuscle_epithelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	ILDR2 RYR3 DOCK5 SRGAP2C HS3ST3B1 HS3ST3A1 SRGAP2 RBFOX1 ROBO1 SRGAP2B	2.03e-08	183	213	10	848fc6dd129150897ee339343e83c645b6e779eb
ToppCell	Primary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	CSMD2 SLIT2 MET SRGAP3 SCN1A FAT3 GRIN2A CTNNA2 EPB41L2 SCAI	3.70e-08	195	213	10	787e95fb59c40bba784544b662fac37606ae1427
ToppCell	facs-Marrow-B-cells-24m-Lymphocytic-precursor_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ILDR2 RYR2 RYR3 USH2A COL12A1 FAT3 CPS1 MYOCD CTNNA2	8.19e-08	160	213	9	c381ec6be8cf887861cc18f831a20db42f953fe1
ToppCell	facs-Marrow-B-cells-24m-Lymphocytic-pre_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ILDR2 RYR2 RYR3 USH2A COL12A1 FAT3 CPS1 MYOCD CTNNA2	8.19e-08	160	213	9	25c8f3d2a6d14ff0ca0b965fce89d3ff22f40585
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ILDR2 RYR3 DOCK5 SRGAP2C HS3ST3A1 SRGAP2 RBFOX1 ROBO1 SRGAP2B	1.52e-07	172	213	9	6c17a1e586a72d1bd80c20c06370429c61dc9f85
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Podocyte\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ILDR2 RYR3 DOCK5 SRGAP2C HS3ST3B1 HS3ST3A1 SRGAP2 RBFOX1 SRGAP2B	1.52e-07	172	213	9	381ae1c3c07d0a424f43455ec571653b192a946a
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ILDR2 RYR3 DOCK5 SRGAP2C HS3ST3B1 HS3ST3A1 SRGAP2 RBFOX1 SRGAP2B	1.68e-07	174	213	9	dbdcdec08f1fc69fcdb5d8a6d78df8ef9c374d89
ToppCell	COVID-19-kidney-Podocyte\|COVID-19 / Disease (COVID-19 only), tissue and cell type	ILDR2 RYR3 SRGAP2C HSPA12A HS3ST3B1 HS3ST3A1 SRGAP2 RBFOX1 SRGAP2B	1.76e-07	175	213	9	a73e3a65fd5c1e09cb0c2dae20c1a7bfcae49223
ToppCell	primary_visual_cortex-Neuronal-glutamatergic_neuron-L5_PT-L5_PT_VISp_C1ql2_Ptgfr\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	STK17B TMEM200A RYR1 RYR3 CACNA1H ALOX12B GPRIN3 TPH2	1.83e-07	127	213	8	fb58f4b4d3722f4b9a2e4946c0244c5b70dd883b
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	ILDR2 RYR3 DOCK5 SRGAP2C HS3ST3B1 HS3ST3A1 SRGAP2 RBFOX1 SRGAP2B	2.57e-07	183	213	9	3c516fe5083f02bad1f464ed284010b4131a833c
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Podocyte\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	ILDR2 RYR3 DOCK5 SRGAP2C HS3ST3B1 HS3ST3A1 SRGAP2 RBFOX1 SRGAP2B	2.57e-07	183	213	9	9c2689d76fc6d30f5ab093428aa669d0a98953cf
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RYR2 RYR3 USH2A MGAM COL12A1 FAT3 CPS1 ROBO1 MYOCD	2.69e-07	184	213	9	2cbed6462fea2622871bb7e49b0df3d984239281
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RYR2 RYR3 USH2A MGAM COL12A1 FAT3 CPS1 ROBO1 MYOCD	2.69e-07	184	213	9	2b19a8c5f823e00812908b23e66bb4e563278aff
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RYR2 RYR3 USH2A MGAM COL12A1 FAT3 CPS1 ROBO1 MYOCD	2.69e-07	184	213	9	ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ILDR2 RYR3 DOCK5 SRGAP2C HS3ST3B1 HS3ST3A1 SRGAP2 RBFOX1 SRGAP2B	2.82e-07	185	213	9	b848b63aff4d9dbb9e66a85876d4c7c6dacd0579
ToppCell	10x5'-GI_small-bowel-Lymphocytic_T_CD4-T_CD4/CD8\|GI_small-bowel / Manually curated celltypes from each tissue	DDX47 ANKRD36C NF1 KMT2A ATP13A3 DYNC1H1 RICTOR JMJD1C MACF1	3.23e-07	188	213	9	ab9b725d6e0cdab8e9ddda6dee09e14730e9a578
ToppCell	10x5'v1-week_12-13-Mesenchymal_osteo-stroma-chondrocyte\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	SCARF2 CHST3 B4GALNT4 SORBS2 MAGEL2 FAM13C DNAH7 TLR3 MEDAG	3.23e-07	188	213	9	c9270517e6940e9793586f67f02431210552f278
ToppCell	LPS_only-Mesenchymal_myocytic-Pericyte-Pericyte_2\|LPS_only / Treatment groups by lineage, cell group, cell type	RYR2 SLIT2 FHAD1 DOCK6 LAMB1 SMTN SHROOM1 ROBO1 CSPP1	5.43e-07	200	213	9	69edc375d85689300d1dbc1217fedc40063ecdcb
ToppCell	390C-Lymphocytic-CD4_T-cell-CD4+_Effector_T_cell-1\|390C / Donor, Lineage, Cell class and subclass (all cells)	TMEM200A FOXO4 CACNA1H LTB4R FBLN7 DOCK8 GPRIN3 INTS6	9.69e-07	158	213	8	ad0e2371c0bc6e53d22518aa3a401cddcde3759f
ToppCell	wk_20-22-Mesenchymal-Myofibro_&_SMC-Early_airway_SMC_1\|wk_20-22 / Celltypes from embryonic and fetal-stage human lung	MRPS30 CDAN1 HS3ST3B1 HS3ST3A1 SHROOM1 ROBO1 MAPK7 UBALD1	1.54e-06	168	213	8	53a982869dbf14f6a948589be9f2f3df3b9a7e97
ToppCell	Adult-Mesenchymal-pericyte_cell-D231\|Adult / Lineage, Cell type, age group and donor	MNX1 RYR2 CACNA1H FAM13C LAMB1 BEND2 SMTN INKA1	1.83e-06	172	213	8	858cee96c1c06160863b4adcd7023c0d678bd50f
ToppCell	facs-Lung-Endomucin_-18m-Endothelial-endothelial_cell_of_lymphatic_vessel\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CDHR1 PCDH12 RYR3 SRGAP3 PPFIBP1 SMTN TLR3 UGGT2	2.09e-06	175	213	8	09163e7030f76d706eccabdb1d5ec45f8412aa75
ToppCell	facs-Lung-Endomucin_-18m-Endothelial-Lymphatic_endothelial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CDHR1 PCDH12 RYR3 SRGAP3 PPFIBP1 SMTN TLR3 UGGT2	2.09e-06	175	213	8	0801cccec6915aefc135262fc74580280fd51aa5
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Podocyte\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	RYR3 DOCK5 SRGAP2C HS3ST3B1 HS3ST3A1 SRGAP2 RBFOX1 SRGAP2B	2.27e-06	177	213	8	4d2cdb57b427a42085c5f9affa0967b15e84dec3
ToppCell	TCGA-Brain-Primary_Tumor-Low_Grade_Glioma\|TCGA-Brain / Sample_Type by Project: Shred V9	KMT2A FOXO4 DYNC1H1 FAM13C NUMA1 RICTOR WDR37 PC	2.27e-06	177	213	8	e8ab340b20cd41554c3841fe980e078e878af35f
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	RYR3 DOCK5 SRGAP2C HS3ST3B1 HS3ST3A1 SRGAP2 RBFOX1 SRGAP2B	2.37e-06	178	213	8	edc7143dc9959d36057cb9471681a23afcbc8cce
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Podocyte\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	RYR3 DOCK5 SRGAP2C HS3ST3B1 HS3ST3A1 SRGAP2 RBFOX1 SRGAP2B	2.68e-06	181	213	8	5bf7aa43f6e6ecce15c95928b91195544d6928c4
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	RYR3 DOCK5 SRGAP2C HS3ST3B1 HS3ST3A1 SRGAP2 RBFOX1 SRGAP2B	2.68e-06	181	213	8	8e751f5d7cd2d328ec0196d874e8a507e8c4e1a9
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Podocyte\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	RYR3 DOCK5 SRGAP2C HS3ST3B1 HS3ST3A1 SRGAP2 RBFOX1 SRGAP2B	2.91e-06	183	213	8	eb559ae3ae252d9365c24ef557dd49b78ed6d898
ToppCell	COVID-19-kidney-Podocyte\|kidney / Disease (COVID-19 only), tissue and cell type	ILDR2 RYR3 DOCK5 SRGAP2C HS3ST3B1 HS3ST3A1 SRGAP2 SRGAP2B	2.91e-06	183	213	8	fb5e2a31b560126e1c04a386c24c365901c60ad7
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	RYR3 DOCK5 SRGAP2C HS3ST3B1 HS3ST3A1 SRGAP2 RBFOX1 SRGAP2B	2.91e-06	183	213	8	612d93df03252d4d2ccdce5a9bc162cfd9172a1a
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Renal_corpuscle_epithelial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	ILDR2 RYR3 DOCK5 SRGAP2C HS3ST3A1 SRGAP2 RBFOX1 SRGAP2B	3.03e-06	184	213	8	7294b379ce4cb8fa75e432559082f93cd106aaf5
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Podocyte\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	RYR3 DOCK5 SRGAP2C HS3ST3B1 HS3ST3A1 SRGAP2 RBFOX1 SRGAP2B	3.15e-06	185	213	8	9197f074e769d54031ec41abfc65fcc0c6552c7e
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	RYR3 DOCK5 SRGAP2C HS3ST3B1 HS3ST3A1 SRGAP2 RBFOX1 SRGAP2B	3.15e-06	185	213	8	ce7d62394b09c26ca65b8cdb280afec5e25bbb62
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Myeloid-TAM-MG-TAM-MG_pro-infl_I-C\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	GPR84 LAPTM5 SRGAP2C LILRB4 SPATA20 HAVCR2 SNX2 INKA1	3.84e-06	190	213	8	259085b9731902ca0956233afafe1db6fc98e851
ToppCell	PCW_13-14-Mesenchymal-Mesenchymal_fibroblastic-mes_immature5_(6)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	DCBLD1 DOCK5 SLIT2 SRGAP3 PPFIBP1 FAT3 MACF1 ROBO1	4.48e-06	194	213	8	b1bb0f846d2865efdd9bc8842b16b9d069785882
ToppCell	BAL-Mild-Myeloid-cDC-cDC-cDC_1\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	GPR84 SRGAP2C DENND1B LILRB4 SRGAP2 AKT1S1 HAVCR2 SRGAP2B	4.65e-06	195	213	8	2f2e29089a8cb748d2c1329c5c8465165b25bc8b
ToppCell	PCW_10-12-Mesenchymal-Mesenchymal_fibroblastic-mes_immature5_(6)\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	DCBLD1 DOCK5 SLIT2 SRGAP3 PPFIBP1 FAT3 MACF1 ROBO1	4.65e-06	195	213	8	0e55fa5b3cbeb7baee3d4ac272a3bf80381ec937
ToppCell	BAL-Mild-Myeloid-cDC-cDC-cDC_1\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	GPR84 SRGAP2C DENND1B LILRB4 SRGAP2 AKT1S1 HAVCR2 SRGAP2B	4.65e-06	195	213	8	c9469e2d31beb30ebb64b3f0a5239e23119fbaa5
ToppCell	COVID-19-Fibroblasts-Intermediate_pathological_FB\|COVID-19 / group, cell type (main and fine annotations)	CSMD2 RYR2 SLIT2 COL12A1 PPFIBP1 LAMB1 ROBO1 EPB41L2	5.01e-06	197	213	8	f1c8936986123a3151140c374fcd62d6705c530b
ToppCell	primary_visual_cortex-Neuronal-glutamatergic_neuron-L5_PT\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	STK17B TMEM200A RYR1 RYR3 SLIT2 CACNA1H ALOX12B	5.09e-06	140	213	7	7cc891d676555609add6fc7880735d948a2ad801
ToppCell	Control_saline-Mesenchymal_fibroblastic-Fibroblasts-Activated_MatrixFB\|Control_saline / Treatment groups by lineage, cell group, cell type	ANKMY1 RYR2 RYR3 SLIT2 FBLN7 LAMB1 SPECC1L MACF1	5.20e-06	198	213	8	0c4d2c68a42f8a9e964e2dd28092fe75f5216834
ToppCell	10x_3'_v2v3-Non-neoplastic-Myeloid-TAM-MG\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	LAPTM5 SRGAP2C LILRB4 SRGAP2 HAVCR2 SRGAP2B EPB41L2 INKA1	5.20e-06	198	213	8	979c391a3b7130e4f91d76a9eb8079fb0f445c4c
ToppCell	Tracheal-10x5prime-Stromal-Myofibroblastic-Muscle_smooth_airway_ASM\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	RYR2 SRL CACNA1H CHST3 FAT3 GRIN2A SMTN MYOCD	5.20e-06	198	213	8	1e1ea54f0c234f3b6d29064c4881d8a0c0949a75
ToppCell	Tracheal-NucSeq-Immune_Myeloid-Macrophage_other-Macro_AW_CX3CR1\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	RYR1 LAPTM5 SRGAP2C LILRB4 GPRIN3 SRGAP2 HAVCR2 SRGAP2B	5.40e-06	199	213	8	744b63fba33b176ab7dde11646ccb313665505f7
ToppCell	Hematolymphoid-Microglia-TYROBP--\|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic	RYR1 LAPTM5 SRGAP2C DOCK8 SRGAP2 HAVCR2 SRGAP2B EPB41L2	5.60e-06	200	213	8	dc344b3ec51d506952e38f0b3a7795d65f9dd4eb
ToppCell	Hematolymphoid-Microglia\|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic	RYR1 LAPTM5 SRGAP2C DOCK8 SRGAP2 HAVCR2 SRGAP2B EPB41L2	5.60e-06	200	213	8	21bcca3b670fe9bac034aef2275d3de4a9a73e2b
ToppCell	LPS_anti-TNF-Mesenchymal_myocytic-Pericyte-Pericyte_2\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	RYR2 SLIT2 FHAD1 HSPA12A LAMB1 SMTN CSPP1 EPB41L2	5.60e-06	200	213	8	786f1ae53e60b5ffbf4bfd393d10b802478148b3
ToppCell	Hematolymphoid-Microglia-TYROBP\|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic	RYR1 LAPTM5 SRGAP2C DOCK8 SRGAP2 HAVCR2 SRGAP2B EPB41L2	5.60e-06	200	213	8	33036d21c1c82109284473a515c4f890b33fdd5c
ToppCell	Hematolymphoid-Microglia-TYROBP----L1-3\|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic	RYR1 LAPTM5 SRGAP2C DOCK8 SRGAP2 HAVCR2 SRGAP2B EPB41L2	5.60e-06	200	213	8	a20dce14f94777687aad57d6fbe3258ad376f63f
ToppCell	Hematolymphoid-Microglia-TYROBP-\|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic	RYR1 LAPTM5 SRGAP2C DOCK8 SRGAP2 HAVCR2 SRGAP2B EPB41L2	5.60e-06	200	213	8	3bba5219453322198e8fdb0921d5f8c403598751
ToppCell	Hematolymphoid-Microglia-TYROBP---\|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic	RYR1 LAPTM5 SRGAP2C DOCK8 SRGAP2 HAVCR2 SRGAP2B EPB41L2	5.60e-06	200	213	8	a8646d0fca99f10827c2d2a12e584660ef7155f1
ToppCell	COVID-19-kidney-Technical/muscle_(PCT)\|kidney / Disease (COVID-19 only), tissue and cell type	CSMD2 RYR2 SCN1A USH2A GRIN2A RBFOX1 CTNNA2	6.71e-06	146	213	7	c55f1bdb6ac43b4118cb27ea7c879527e1afcbab
ToppCell	Hippocampus-Neuronal-Excitatory-eN1(Slc17a7)-eN1_2\|Hippocampus / BrainAtlas - Mouse McCarroll V32	CSMD2 RYR3 CAMKV CACNA1H FAT3 KIAA1671 NSMF	7.02e-06	147	213	7	8f725ff8fb4ced5db2643e80669d3f7945b820ab
ToppCell	facs-Marrow-T-cells-24m-Lymphocytic-precursor_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HSPA12A MAGEL2 COL12A1 TMC2 FAM13C GRIN2A PC	1.12e-05	158	213	7	8c7108f2c40d97a317762ba0b8eca76542b2ebaf
ToppCell	facs-Marrow-T-cells-24m-Lymphocytic-pre_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HSPA12A MAGEL2 COL12A1 TMC2 FAM13C GRIN2A PC	1.12e-05	158	213	7	f296ca24fdedc33f1d24b79e7660763114ce7fa3
ToppCell	COVID-19-kidney-Technical/muscle_(Mes)\|kidney / Disease (COVID-19 only), tissue and cell type	CSMD2 RYR1 RYR2 USH2A FAT3 RBFOX1 CTNNA2	1.17e-05	159	213	7	5335cbcdeaf2bbd0268bbfe0e45c8c0d288e640d
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell-mesangial_typical-aged\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	TMEM200A HS3ST3B1 HS3ST3A1 DNTT DOCK8 ROBO1 EPB41L2	1.17e-05	159	213	7	5ca96db4281abb5f646150ccf36adc66ab201c78
ToppCell	facs-Lung-nan-3m-Endothelial-Capillary_Type_1_Cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CLTRN RYR2 CACNA1H B4GALNT4 GPRIN3 GRM2 MYOCD	1.22e-05	160	213	7	f2cdee5a9e3b0eb125d6be7b5d239eb04333ae41
ToppCell	P07-Mesenchymal-developing_mesenchymal_cell-mesenchymal_immature_unknown_1\|P07 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	SCARF2 SLIT2 ARAP1 FAT3 SPECC1L MACF1 CTNNA2	1.27e-05	161	213	7	b19f82dd98a3064581793711bb70373f18abecd9
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell-mesangial_typical\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	STK17B TMEM200A HS3ST3B1 HS3ST3A1 COL12A1 ROBO1 EPB41L2	1.27e-05	161	213	7	1b805f77790aeb8a71b08bfac2fe2eed7343258f
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Macula_Densa_Cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	RYR3 MET DNAH6 LAMB4 PHOSPHO2 RBFOX1 CTNNA2	1.32e-05	162	213	7	373513f9d0e5007b2e10a8b78d4909dcce9e3b62
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell-mesangial_typical-aged\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	STK17B TMEM200A HS3ST3B1 HS3ST3A1 ROBO1 PADI6 EPB41L2	1.43e-05	164	213	7	f6a961fa2002da7d9679f32af99e1314c0593ef9
ToppCell	Hippocampus-Neuronal-Excitatory-eN1(Slc17a7)\|Hippocampus / BrainAtlas - Mouse McCarroll V32	SSTR4 RYR3 CAMKV CACNA1H GRIN2A NSMF RBFOX1	1.67e-05	168	213	7	6db453cbbbaf4144a86fadcfa5805d33396713b5
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Podocyte\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	ILDR2 RYR3 DOCK5 SRGAP2C HS3ST3B1 SRGAP2 RBFOX1	1.67e-05	168	213	7	e96859dbf51cf8c4def8ee8db132f4d874fb4381
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	ILDR2 RYR3 DOCK5 SRGAP2C SRGAP2 RBFOX1 ROBO1	1.67e-05	168	213	7	315ca578c945aeeb77acda2727f3e6db8b43f43e
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c13-MKI67-CCL5_l\|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)	LIN9 C20orf203 CDT1 POLE2 SPAG5 CDCA7 FANCI	1.74e-05	169	213	7	481e611b5fface58f1630f206c0b04fb54e24011
ToppCell	facs-Brain_Non-Myeloid-Cerebellum-24m-Lymphocytic-T_cell\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	STK17B LAPTM5 CDT1 LTB4R HS3ST3B1 DOCK8 INKA1	1.88e-05	171	213	7	c60313b045cb77c0923ddb81bbd1a654aa1087c5
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-glomerular_mesenchymal_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	STK17B TMEM200A HS3ST3B1 HS3ST3A1 COL12A1 ROBO1 EPB41L2	1.95e-05	172	213	7	08a3fe536b1b064c5ee7779bc2b1115a5963a26b
ToppCell	5'-Adult-Appendix-Hematopoietic-T_cells-Treg\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	RYR1 LAPTM5 HECW2 HS3ST3B1 FBLN7 INPP5F TRBV12-5	1.95e-05	172	213	7	c74c1d47b133eb5d0f762a06e421252a76b4672b
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	STK17B TMEM200A HS3ST3B1 HS3ST3A1 COL12A1 ROBO1 EPB41L2	1.95e-05	172	213	7	553701349444eb366df3c11f54bb093434f153c6
ToppCell	facs-Trachea-24m-Mesenchymal-fibroblast-fibroblast_of_trachea-\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	MLKL TNRC18 PIK3C2A PTCD3 INTS6 CAPRIN2 PC	2.18e-05	175	213	7	bb898796662b97f7459b7dda7cecf6a9bde8b055
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell-mesangial_typical-aged\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	STK17B TMEM200A HS3ST3A1 COL12A1 DOCK8 GPRIN3 EPB41L2	2.18e-05	175	213	7	1b4cefae400bf756d09ece32d3f5c0bd4c6ad73f
ToppCell	droplet-Heart-nan-3m\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYO9A PRPF6 RYR2 CEP350 JMJD1C MACF1 MYOCD	2.26e-05	176	213	7	749b47eac5436fa34e0d243ffbc6f1897f4e431e
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Renal_corpuscle_epithelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	RYR3 DOCK5 SRGAP2C HS3ST3B1 SRGAP2 RBFOX1 SRGAP2B	2.52e-05	179	213	7	7394e77e665bf16d3733df91bb12907be460ab44
ToppCell	facs-Lung-18m-Hematologic-myeloid-myeloid_dendritic_cell-dendritic_type_2\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	RYR1 LAPTM5 SRGAP3 LTB4R DOCK8 HAVCR2 TLR3	2.52e-05	179	213	7	b7a2429d07d7146b32b3552a5f2a2542105a71e0
ToppCell	droplet-Liver-LIVER_HEP-30m\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PCDH12 HSPA12A HECW2 KMT2A DOCK6 MACF1 EPB41L2	2.61e-05	180	213	7	dd1b10c7f5a0fbc63163844ca1882884a24a84d3
ToppCell	droplet-Liver-LIVER_HEP\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PCDH12 HSPA12A HECW2 KMT2A DOCK6 MACF1 EPB41L2	2.61e-05	180	213	7	423454e3390080ae03bb3cbb267255ebfe4df080
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Mesenchymal-glomerular_mesenchymal_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	SCARF2 STK17B TMEM200A HS3ST3A1 COL12A1 GPRIN3 EPB41L2	2.70e-05	181	213	7	a2058d658f07ab6f0a28d2622f3090b4cde6f763
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	SCARF2 STK17B TMEM200A HS3ST3A1 COL12A1 GPRIN3 EPB41L2	2.70e-05	181	213	7	526e858a848470b6d2d5248788004d9735ed3add
ToppCell	3'-Parenchyma_lung-Endothelial-Lymphatic_EC-endothelial_cell_of_lymphatic_vessel-Lymphatic_EC_differentiating-Lymphatic_EC_differentiating_L.2.5.1.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	DOCK5 HECW2 DOCK6 PPFIBP1 INTS6 MACF1 EPB41L2	2.70e-05	181	213	7	e898ecb8d8f2eb2204225b7b0d665cadcd241139
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD\|renal_cortex_nuclei / Celltypes from Cells and Nuclei per compartment and clinical group	RYR2 TNRC18 USH2A FAT3 GRIN2A KIAA1671 RBFOX1	2.70e-05	181	213	7	c80ffa2ded5975a88e9a1a7d333196f95237bf0a
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_3\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	MYO9A MET SRGAP3 COL12A1 PPFIBP1 GRIN2A SLC9A3	2.80e-05	182	213	7	eb138aa1dca9373f1586600f258df06dcf56d81f
ToppCell	Children_(3_yrs)-Endothelial-alveolar_capillary_endothelial_cell_(Cap2;_aerocyte)-D046\|Children_(3_yrs) / Lineage, Cell type, age group and donor	ILDR2 PCDH12 HECW2 PPFIBP1 GRIN2A CSPP1 EPB41L2	2.80e-05	182	213	7	a20017b6a4f9a6a29e090e4dbd7c02ed1495bd50
ToppCell	Control-Stromal_mesenchymal-Lung_smooth_muscle-MatrixFB_->_Myofibroblast\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	RYR2 DOCK5 MET HS3ST3A1 FAT3 RBFOX1 MYOCD	2.90e-05	183	213	7	7eae9b3b4d1c9b135fa7cff348393d4adec474b4
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	RYR3 DOCK5 SRGAP2C SRGAP2 RBFOX1 ROBO1 SRGAP2B	2.90e-05	183	213	7	7c4b775f351794a3de06bd503eecbc8ae8577c44
ToppCell	T_cells-Resident_memory_CD8+_T_cells\|World / Immune cells in Kidney/Urine in Lupus Nephritis	STK17B CDHR1 TMEM200A SRGAP3 SOAT2 RBL2 KIAA1671	3.00e-05	184	213	7	e04cabff33a8e36967622ec3e5b37b89afa7e148
ToppCell	wk_08-11-Epithelial-PNS-PCP4+_neuron\|wk_08-11 / Celltypes from embryonic and fetal-stage human lung	INSM2 SORBS2 NUP98 GRIN2A KCNRG RBFOX1 CTNNA2	3.00e-05	184	213	7	eac2a9089913f33a961ba11519b53645790f2056
ToppCell	primary_visual_cortex-Neuronal-glutamatergic_neuron-L5_PT-L5_PT_VISp_Chrna6\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	CDHR1 TMEM200A SLIT2 PPFIBP1 FAT3 GRM2	3.08e-05	125	213	6	fac8a9bff83abb8976013ff7d2b4ce0b68fbb70a
ToppCell	PCW_13-14-Mesenchymal-Mesenchymal_fibroblastic-mes_Arw_fibro_(16)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	NKX3-2 RYR2 RYR3 HS3ST3B1 HS3ST3A1 PI16 ROBO1	3.11e-05	185	213	7	7dcdc009c5681ee05dd18968f7e85c3403fe34af
ToppCell	PBMC_fresh-frozen-Severe-critical_convalescent_d42-56-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c13-MKI67-CCL5_l\|Severe-critical_convalescent_d42-56 / Compartment, severity and other cell annotations on 10x 3' data (130k)	LIN9 CDT1 POLE2 GPRIN3 SPAG5 CDCA7 FANCI	3.22e-05	186	213	7	993c58ef4445bf81bbc9b489635883848b5b4c8e
ToppCell	3'-Parenchyma_lung-Endothelial-Lymphatic_EC-endothelial_cell_of_lymphatic_vessel-Lymphatic_EC_differentiating\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	DOCK5 HECW2 DOCK6 PPFIBP1 INTS6 MACF1 EPB41L2	3.22e-05	186	213	7	20340a5b5cc7f07386498a4ef937d6fbc9e347c4
ToppCell	Entopeduncular-Endothelial-ENDOTHELIAL_TIP-Dcn_1\|Entopeduncular / BrainAtlas - Mouse McCarroll V32	FBLN7 COL12A1 PI16 LAMB1 FANCI MEDAG	3.22e-05	126	213	6	fe6900eb37e4f09465a1276586c73dd38545fa2a
ToppCell	Entopeduncular-Endothelial-ENDOTHELIAL_TIP\|Entopeduncular / BrainAtlas - Mouse McCarroll V32	FBLN7 COL12A1 PI16 LAMB1 FANCI MEDAG	3.22e-05	126	213	6	3d507f829882d043f633db2612b76936e2042445
ToppCell	Entopeduncular-Endothelial-ENDOTHELIAL_TIP-Dcn_1-Dcn_1_1-Endothelial_Tip.Dcn_(Dcn)-\|Entopeduncular / BrainAtlas - Mouse McCarroll V32	FBLN7 COL12A1 PI16 LAMB1 FANCI MEDAG	3.22e-05	126	213	6	f1f24b06d301c266226d1a59dd28585f5ac68f29
ToppCell	Entopeduncular-Endothelial-ENDOTHELIAL_TIP-Dcn_1-Dcn_1_1\|Entopeduncular / BrainAtlas - Mouse McCarroll V32	FBLN7 COL12A1 PI16 LAMB1 FANCI MEDAG	3.22e-05	126	213	6	1ac4cc747e466bc79e33b97608b19ad29a7a6a41
ToppCell	Entopeduncular-Endothelial-ENDOTHELIAL_TIP-Dcn_1-Dcn_1_1-Endothelial_Tip.Dcn_(Dcn)\|Entopeduncular / BrainAtlas - Mouse McCarroll V32	FBLN7 COL12A1 PI16 LAMB1 FANCI MEDAG	3.22e-05	126	213	6	2de551d7a8765afec1da8852727c79fec90f45f8
ToppCell	COVID-19-Fibroblasts-Airway_smooth_muscle\|COVID-19 / group, cell type (main and fine annotations)	RYR2 SLIT2 CACNA1H COL12A1 FAM13C SMTN MYOCD	3.33e-05	187	213	7	464a0c3b92b778911b5f9cd73642e09e3472063a
Drug	cis-diammineplatinum(II	RYR1 RYR2 RYR3	7.96e-07	3	212	3	CID000159790
Drug	2-hydroxyheptanoic acid	RYR1 RYR2 RYR3	7.96e-07	3	212	3	CID002750949
Drug	8N3-cADPR	RYR1 RYR2 RYR3	7.96e-07	3	212	3	CID000127713
Drug	aminodantrolene	RYR1 RYR2 RYR3	7.96e-07	3	212	3	CID009570289
Drug	2-hydroxycarbazole	RYR1 RYR2 RYR3	7.96e-07	3	212	3	CID000093551
Drug	Ryanodyl 3-(pyridine-3-carboxylate	RYR1 RYR2 RYR3	7.96e-07	3	212	3	CID005748312
Drug	Yohimbine hydrochloride [65-19-0]; Up 200; 10.2uM; MCF7; HT_HG-U133A	STK17B SSTR4 NF1 SCN1A ATP13A3 LTB4R DOCK6 SOAT2 BLZF1 SLF2 FANCI	2.67e-06	198	212	11	2755_UP
Drug	gadolinium	RYR1 RYR2 RYR3 NEU1 NF1 CANT1 PKD1 CACNA1H USH2A TRPV1 KCNK10	2.80e-06	199	212	11	CID000023982
Drug	gallopamil	RYR1 RYR2 RYR3 PKD1 CACNA1H MGAM IK	2.98e-06	67	212	7	CID000001234
Drug	PCB74	RYR1 RYR2 RYR3	3.16e-06	4	212	3	CID000036218
Drug	148504-47-6	RYR1 RYR2 RYR3	3.16e-06	4	212	3	CID006444275
Drug	SC 38249	RYR1 RYR2 RYR3	3.16e-06	4	212	3	CID000134834
Drug	AC1L1U7A	RYR1 RYR2 RYR3	3.16e-06	4	212	3	CID000035682
Drug	ethosuximide	SPAST LIN9 RYR1 RYR2 RYR3 PKD1 CACNA1H	5.83e-06	74	212	7	CID000003291
Drug	loperamide	RYR1 RYR2 RYR3 CGN PKD1 CACNA1H SORBS2 GRIN2A	6.37e-06	105	212	8	CID000003954
Drug	Thimerosal	MYO9A CDHR1 PRPF6 STK35 LIN9 RYR3 MAP3K3 CEP350 NF1 DENND1B PIK3C2A KMT2A SRL CDT1 ATP13A3 DOCK6 SORBS2 MAGEL2 PPFIBP1 CPS1 JMJD1C KCNRG INTS6 MEDAG PC CSPP1 DCAF4 SNX2	7.13e-06	1199	212	28	ctd:D013849
Drug	CNS 1145	RYR1 RYR2 RYR3 PKD1 CACNA1H	1.28e-05	33	212	5	CID000190902
Drug	IHC-64	RYR1 RYR2 RYR3 PKD1 CACNA1H	1.28e-05	33	212	5	CID000162753
Drug	chloro-m-cresol	RYR1 RYR2 RYR3	1.56e-05	6	212	3	CID000012008
Drug	MBED	RYR1 RYR2 RYR3	1.56e-05	6	212	3	CID000129958
Drug	AC1O528X	RYR1 RYR2 RYR3	1.56e-05	6	212	3	CID006475857
Drug	NSC114784	RYR1 RYR2 RYR3	1.56e-05	6	212	3	CID000419425
Drug	Pindolol [13523-86-9]; Down 200; 16.2uM; HL60; HG-U133A	MYO9A TUBGCP2 MET DGUOK KMT2A ADAM17 LTB4R AMBRA1 SPATA20 RPAP1	1.68e-05	197	212	10	1392_DN
Drug	Diethylcarbamazine citrate [1642-54-2]; Down 200; 10.2uM; MCF7; HT_HG-U133A	SPAST MNX1 ANKMY1 MRPS30 NF1 DOCK6 SLC4A2 PPP2R1B SLF2 GABPB1	1.76e-05	198	212	10	5485_DN
Drug	Isocarboxazid [59-63-2]; Down 200; 17.2uM; MCF7; HT_HG-U133A	STK17B FAAH HIRA MET ZBED4 ADAM17 NUP98 LAMB1 SMTN CAPRIN2	1.76e-05	198	212	10	3424_DN
Drug	bepridil	ASIC3 RYR1 RYR2 RYR3 PKD1 CACNA1H SPAG5 IK	2.43e-05	126	212	8	CID000002351
Drug	AC1L380G	RYR1 RYR2 RYR3 MGAM	2.54e-05	19	212	4	CID000084698
Drug	[[(2R,3S,4R)-5-(2-amino-6-oxo-3H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl] [(2R,3S,4R,5R)-3,4,5-trihydroxyoxolan-2-yl]methyl hydrogen phosphate	RYR1 RYR2 RYR3	2.71e-05	7	212	3	CID009547999
Drug	Azumoleno	RYR1 RYR2 RYR3	2.71e-05	7	212	3	CID000056259
Drug	mag-indo-1	RYR1 RYR3 MGAM	2.71e-05	7	212	3	CID000131881
Drug	Br2BAPTA	RYR1 RYR2 RYR3	2.71e-05	7	212	3	CID003081001
Drug	gabapentin	ASIC3 RYR1 RYR2 RYR3 CGN PKD1 CACNA1H GRIN2A GRM2	3.06e-05	169	212	9	CID000003446
Drug	lavendustin A	RYR1 RYR2 RYR3 MET PIK3C2A PKD1 CACNA1H GRIN2A IK	3.36e-05	171	212	9	CID000003894
Drug	riluzole	ASIC3 RYR1 RYR2 RYR3 PKD1 CACNA1H GRIN2A GRM2 KCNK10	3.85e-05	174	212	9	CID000005070
Drug	indo-1/AM	RYR1 RYR2 RYR3 IK	3.86e-05	21	212	4	CID000123918
Drug	lanthanum	RYR1 RYR2 RYR3 PKD1 CACNA1H MGAM IK MAPK7	4.20e-05	136	212	8	CID000023926
Drug	AC1L2AC7	RYR1 RYR2 RYR3 PKD1 CACNA1H SOAT2	4.47e-05	69	212	6	CID000068733
Drug	Securinine [5610-40-2]; Up 200; 18.4uM; MCF7; HT_HG-U133A	CDK18 STK17B RYR1 LAPTM5 CASP4 CPS1 PPP2R1B RBFOX1 GABPB1	6.47e-05	186	212	9	6831_UP
Drug	Dantrolene-13C3	RYR1 RYR2 RYR3 PIK3C2A PKD1 CACNA1H GRIN2A GRM2	6.62e-05	145	212	8	CID000002951
Drug	Ketanserin tartrate hydrate [83846-83-7]; Down 200; 7uM; PC3; HT_HG-U133A	CEP350 MET NF1 KMT2A CDT1 CPLANE1 RBL2 NUMA1 AMBRA1	7.31e-05	189	212	9	6649_DN
Drug	AC1L1KS5	RYR1 RYR2 RYR3 PIK3C2A PKD1 CACNA1H TRPV1 RBL2 GRM2 INTS6 KCNK10 MAPK7	7.46e-05	334	212	12	CID000005631
Drug	T0702	RYR1 RYR2 RYR3 TRPV1	7.93e-05	25	212	4	CID000005908
Drug	Butylparaben [94-26-8]; Down 200; 20.6uM; PC3; HT_HG-U133A	ANKMY1 HIRA CDT1 PRRC2B PPFIBP1 NUMA1 UBA6 CSPP1 DCAF4	7.93e-05	191	212	9	4647_DN
Drug	Bay K 8644	RYR1 RYR2 RYR3 NF1 PKD1 CACNA1H MGAM IK	8.40e-05	150	212	8	CID000002303
Drug	5'-adenylyl (beta,gamma-methylene)diphosphonate	RYR1 RYR3	8.63e-05	2	212	2	ctd:C005147
Drug	K-Cl	GIPC1 MYO9A RYR1 RYR2 RYR3 CGN LTB4R MGAM POLE2 LAMB1 GRIN2A GRM2 SMTN KCNK10 IK MAPK7	8.84e-05	567	212	16	CID000004873
Drug	nisoldipine	RYR1 RYR2 RYR3 PKD1 CACNA1H IK	8.93e-05	78	212	6	CID000004499
Drug	Azaguanine-8 [134-58-7]; Down 200; 26.2uM; MCF7; HT_HG-U133A	SPAST TUBGCP2 FAAH ZBED4 ZBTB40 KMT2A SMTN MACF1 CSPP1	8.93e-05	194	212	9	1670_DN
Drug	Tadjakonine [11087-94-8]; Down 200; 7.4uM; MCF7; HT_HG-U133A	HIRA MET NF1 HS3ST3A1 ARAP1 LAMB4 TRPV1 RBFOX1 MAPK7	8.93e-05	194	212	9	4424_DN
Drug	PCB 95	RYR1 RYR2 RYR3	9.10e-05	10	212	3	CID000038012
Drug	JZL 184	FAAH SLIT2 ROBO1	9.10e-05	10	212	3	ctd:C534333
Drug	Fluorometholone [426-13-1]; Down 200; 10.6uM; MCF7; HT_HG-U133A	TUBGCP2 HIRA NF1 CANT1 DOCK6 AMBRA1 SMTN PC EPB41L2	9.66e-05	196	212	9	6247_DN
Drug	Naltrexone hydrochloride dihydrate [16676-29-2]; Down 200; 9.6uM; PC3; HT_HG-U133A	KDM4C NKX3-2 NF1 ZBED4 TRPV1 NUMA1 AMBRA1 MAPK7 PC	9.66e-05	196	212	9	5765_DN
Drug	Dorzolamide hydrochloride [130693-82-2]; Down 200; 11uM; PC3; HT_HG-U133A	ZNF671 TUBGCP2 RYR2 HIRA NF1 DOCK6 USB1 MAPK7 DCAF4	1.00e-04	197	212	9	5785_DN
Drug	(-) -Levobunolol hydrochloride [27912-14-7]; Up 200; 12.2uM; MCF7; HT_HG-U133A	CDK18 NF1 SRGAP3 CACNA1H SOAT2 ARAP1 PPP2R1B RBFOX1 MAPK7	1.00e-04	197	212	9	4134_UP
Drug	Nicergoline; Down 200; 8.2uM; PC3; HT_HG-U133A	ZNF671 RYR2 HIRA NF1 ZBED4 PRRC2B TRPV1 MAPK7 PC	1.00e-04	197	212	9	5775_DN
Drug	Sulfadiazine [68-35-9]; Down 200; 16uM; PC3; HT_HG-U133A	MNX1 ARAP1 TRPV1 AMBRA1 BLZF1 NSMF RPAP1 SLF2 CSPP1	1.00e-04	197	212	9	1810_DN
Drug	Terbutaline hemisulfate [23031-32-5]; Down 200; 7.2uM; MCF7; HT_HG-U133A	SPAST NUP98 AMBRA1 INPP5F BLZF1 UBA6 MACF1 ROBO1 GABPB1	1.00e-04	197	212	9	6240_DN
Drug	Solasodine [126-17-0]; Up 200; 9.6uM; MCF7; HT_HG-U133A	RYR1 CAMKV SRGAP3 LILRB4 LAMB4 GRIN2A CPS1 PPP2R1B KCNK10	1.04e-04	198	212	9	6025_UP
Drug	Dienestrol [84-17-3]; Down 200; 15uM; PC3; HT_HG-U133A	KDM4C ASIC3 NF1 CDT1 DOCK6 AMBRA1 PPP2R1B MAPK7 PC	1.04e-04	198	212	9	5727_DN
Drug	Noscapine [128-62-1]; Up 200; 9.6uM; MCF7; HT_HG-U133A	CEP350 NF1 ADAM17 LTB4R USB1 LAMB1 BLZF1 FANCI RBFOX1	1.08e-04	199	212	9	2745_UP
Drug	Stachydrine hydrochloride; Down 200; 22.2uM; HL60; HG-U133A	HIRA KMT2A PRRC2B RBL2 GPATCH2 SRGAP2 JMJD1C UBA6 SNX2	1.08e-04	199	212	9	1751_DN
Drug	lamotrigine	ASIC3 RYR1 RYR2 RYR3 PKD1 CACNA1H GRIN2A	1.09e-04	116	212	7	CID000003878
Drug	AC1NBU2S	RYR1 RYR2 RYR3 PKD1 CACNA1H LTB4R MGAM	1.15e-04	117	212	7	CID004473765
Drug	AC1L1G72	LAMB4 LAMB1 LAMB2	1.24e-04	11	212	3	CID000003553
Drug	PCB 66	RYR1 RYR2 RYR3	1.24e-04	11	212	3	CID000036185
Drug	R 478	RYR1 RYR2 RYR3	1.24e-04	11	212	3	CID000084223
Drug	8-amino-cADPR	RYR1 RYR2 RYR3	1.24e-04	11	212	3	CID003081323
Drug	Ryanodine	RYR1 RYR2 RYR3	1.65e-04	12	212	3	ctd:D012433
Drug	nonivamide	RYR1 MGAM TRPV1	1.65e-04	12	212	3	CID000002998
Drug	Cinildipine	RYR1 RYR2 RYR3 PKD1 CACNA1H	1.73e-04	56	212	5	CID000002752
Disease	congenital myopathy 1A (implicated_via_orthology)	RYR1 RYR2 RYR3	3.35e-07	3	206	3	DOID:3529 (implicated_via_orthology)
Disease	malignant hyperthermia (implicated_via_orthology)	RYR1 RYR2 RYR3	3.35e-07	3	206	3	DOID:8545 (implicated_via_orthology)
Disease	Lissencephaly	LAMB1 MACF1 CTNNA2	6.60e-06	6	206	3	C0266463
Disease	autistic disorder (is_implicated_in)	KDM4C MET NF1 LAMB1 TPH2	1.09e-05	42	206	5	DOID:12849 (is_implicated_in)
Disease	Autistic Disorder	MET NF1 CACNA1H MAGEL2 LAMB1 GRIN2A JMJD1C RBFOX1 TPH2 ROBO1	1.64e-05	261	206	10	C0004352
Disease	attention deficit hyperactivity disorder, substance abuse, antisocial behaviour measurement	STIMATE RYR2 MRPS30 SLIT2 MET HSPA12A DENND1B USH2A PRRC2B GRIN2A STK32C CDCA7 FEZF1 RBFOX1 PRKDC CTNNA2 SCAI	5.20e-05	801	206	17	EFO_0003888, EFO_0007052, MONDO_0002491
Disease	Intellectual Disability	PCDH12 NF1 SRGAP3 SCN1A ZBTB40 DYNC1H1 DOCK8 SPECC1L WDR37 MACF1 CTNNA2	3.30e-04	447	206	11	C3714756
Disease	HIV-1 infection, Susceptibility to viral and mycobacterial infections	KDM4C ADAM17 PC	4.06e-04	21	206	3	EFO_0000180, Orphanet_391311
Disease	Arthrogryposis	MYO9A DYNC1H1 MAGEL2	4.06e-04	21	206	3	C0003886
Disease	Varicose veins	KMT2A SRL FBLN7 SORBS2 DOCK8 PPFIBP1 RP1L1	4.33e-04	193	206	7	HP_0002619
Disease	urate measurement, bone density	GIPC1 DDX59 DOCK5 USH2A PRRC2B PPFIBP1 FEZF1 RBFOX1 TPH2 ROBO1 UGGT2 PRKDC CTNNA2	4.43e-04	619	206	13	EFO_0003923, EFO_0004531
Disease	Profound Mental Retardation	NF1 SRGAP3 SCN1A ZBTB40 DYNC1H1 DOCK8	4.48e-04	139	206	6	C0020796
Disease	Mental Retardation, Psychosocial	NF1 SRGAP3 SCN1A ZBTB40 DYNC1H1 DOCK8	4.48e-04	139	206	6	C0025363
Disease	Mental deficiency	NF1 SRGAP3 SCN1A ZBTB40 DYNC1H1 DOCK8	4.48e-04	139	206	6	C0917816
Disease	Pachygyria	LAMB1 CTNNA2	4.78e-04	5	206	2	C0266483
Disease	Agyria	LAMB1 CTNNA2	4.78e-04	5	206	2	C1879312
Disease	response to silica exposure, pneumoconiosis	LAMB4 LAMB1	4.78e-04	5	206	2	EFO_0005853, MONDO_0015926
Disease	generalised epilepsy	RYR2 SCN1A RBFOX1 PADI6	4.81e-04	52	206	4	EFO_0005917
Disease	Neurodevelopmental Disorders	SPAST SRGAP3 SCN1A KMT2A DOCK8	4.99e-04	93	206	5	C1535926
Disease	Epilepsy, Benign Psychomotor, Childhood	SLIT2 TRPV1 GRM2	5.36e-04	23	206	3	C0393672
Disease	Epilepsy, Lateral Temporal	SLIT2 TRPV1 GRM2	5.36e-04	23	206	3	C0393682
Disease	Uncinate Epilepsy	SLIT2 TRPV1 GRM2	5.36e-04	23	206	3	C0014558
Disease	Epilepsy, Temporal Lobe	SLIT2 TRPV1 GRM2	5.36e-04	23	206	3	C0014556
Disease	primary pulmonary hypertension (is_implicated_in)	RYR1 ATP13A3	7.14e-04	6	206	2	DOID:14557 (is_implicated_in)
Disease	Epilepsy, Generalized	SCN1A CACNA1H	7.14e-04	6	206	2	C0014548
Disease	X-16570 measurement	FAAH CPS1	7.14e-04	6	206	2	EFO_0800759
Disease	diastolic blood pressure, systolic blood pressure	MYO9A RBBP8NL RYR2 CEP350 DOCK5 MET DENND1B FAM13C DNAH7 KIAA1671 RBFOX1 MYOCD SNX2	9.18e-04	670	206	13	EFO_0006335, EFO_0006336
Disease	abnormal vaginal discharge smell	CYP24A1 SORBS2	9.95e-04	7	206	2	EFO_0009408
Disease	N-palmitoylglycine measurement	FAAH CPS1	9.95e-04	7	206	2	EFO_0800342
Disease	urolithiasis	GIPC1 CYP24A1 CPS1 EPB41L2	9.96e-04	63	206	4	MONDO_0024647
Disease	Malignant mesothelioma	AGO2 RYR2 MET BCL10 COL12A1	1.03e-03	109	206	5	C0345967
Disease	diet measurement	ILDR2 GATAD2B MRPS30 NF1 HECW2 CACNA1H HS3ST3B1 ANAPC4 MGAM JMJD1C SMTN RPAP1 FEZF1 RBFOX1 ROBO1 PRKDC CTNNA2	1.17e-03	1049	206	17	EFO_0008111
Disease	Acute erythroleukemia - M6a subtype	KMT2A NUP98	1.32e-03	8	206	2	C2930975
Disease	Acute myeloid leukemia FAB-M6	KMT2A NUP98	1.32e-03	8	206	2	C2930976
Disease	Acute erythroleukemia - M6b subtype	KMT2A NUP98	1.32e-03	8	206	2	C2930977
Disease	Acute erythroleukemia	KMT2A NUP98	1.32e-03	8	206	2	C2930974
Disease	tyrosine-protein kinase receptor TYRO3 measurement	MGAM RPAP1	1.32e-03	8	206	2	EFO_0020829
Disease	smoking status measurement	STK17B STIMATE RYR2 SLIT2 MET DENND1B CAMKV HECW2 CC2D2A USH2A PRRC2B FAT3 GRIN2A STK32C FEZF1 RBFOX1 CTNNA2 SCAI	1.37e-03	1160	206	18	EFO_0006527
Disease	response to ketamine	SLIT2 ALOX12B DOCK8 KIAA1671	1.40e-03	69	206	4	EFO_0009748
Disease	Polydactyly	DDX59 CC2D2A CPLANE1 IFT88 CSPP1	1.41e-03	117	206	5	C0152427
Disease	mean reticulocyte volume	AGO2 KDM4C STK17B CEP350 C20orf203 ZBTB40 CC2D2A SRL HSF2BP SPECC1L JMJD1C PPP2R1B CDCA7 EPB41L2	1.55e-03	799	206	14	EFO_0010701
Disease	22q11 partial monosomy syndrome	HIRA JMJD1C	1.69e-03	9	206	2	C3266101
Disease	Autosomal Recessive Polycystic Kidney Disease	SLC4A2 IFT88	1.69e-03	9	206	2	C0085548
Disease	Congenital ocular coloboma (disorder)	LAMB1 WDR37	1.69e-03	9	206	2	C0009363
Disease	serine measurement	DYNC1H1 GRIN2A CPS1	1.86e-03	35	206	3	EFO_0009774
Disease	aortic measurement	RYR2 SRL JMJD1C SMTN DCAF4 SNX2 SCAI	2.00e-03	251	206	7	EFO_0020865
Disease	cystic kidney disease (implicated_via_orthology)	SLIT2 ROBO1	2.10e-03	10	206	2	DOID:2975 (implicated_via_orthology)
Disease	Asymmetric crying face association	HIRA JMJD1C	2.10e-03	10	206	2	C0431406
Disease	decadienedioic acid (C10:2-DC) measurement	ACOT2 DCAF4	2.10e-03	10	206	2	EFO_0800598
Disease	22q11 Deletion Syndrome	HIRA JMJD1C	2.10e-03	10	206	2	C2936346
Disease	Drugs used in diabetes use measurement	STK17B NF1 ARAP1 DNAH7 JMJD1C RPAP1 MACF1	2.18e-03	255	206	7	EFO_0009924
Disease	polymyositis (is_marker_for)	SLIT2 ROBO1	2.56e-03	11	206	2	DOID:0080745 (is_marker_for)
Disease	Congenital ichthyosis of skin	CASP14 ALOX12B	2.56e-03	11	206	2	cv:C0020758
Disease	serum metabolite measurement	DDX47 KDM4C CYP24A1 FAAH SLIT2 HSPA12A SULT2A1 DOCK6 LAMB4 SORBS2 MAGEL2 LAMB1 CPS1 SLC9A3 RBFOX1	2.75e-03	945	206	15	EFO_0005653
Disease	acute myeloid leukemia (implicated_via_orthology)	KMT2A NUP98	3.06e-03	12	206	2	DOID:9119 (implicated_via_orthology)
Disease	volumetric bone mineral density	FHAD1 ZBTB40 RBFOX1	3.15e-03	42	206	3	EFO_0007620
Disease	colorectal cancer	STIMATE DCBLD1 HAO1 HSPA12A ZBTB40 CHST3 LILRB4 RBFOX1 CAPRIN2 TPH2 MACF1	3.64e-03	604	206	11	MONDO_0005575
Disease	hemoglobin A1 measurement	STIMATE SRGAP3 CDT1 ARAP1 ANAPC4 MGAM SRGAP2 JMJD1C RP1L1 MACF1	3.75e-03	520	206	10	EFO_0007629
Disease	esophagus squamous cell carcinoma (is_implicated_in)	KDM4C CYP24A1 RICTOR	3.83e-03	45	206	3	DOID:3748 (is_implicated_in)
Disease	anti-thyroglobulin antibody measurement	CYP24A1 HS3ST3A1 SLC9A3	4.08e-03	46	206	3	EFO_0009896
Disease	autosomal dominant polycystic kidney disease (implicated_via_orthology)	PKD1 IFT88	4.18e-03	14	206	2	DOID:898 (implicated_via_orthology)
Disease	lentiform nucleus measurement	GATAD2B EPB41L2	4.18e-03	14	206	2	EFO_0004913
Disease	Testicular Germ Cell Tumor	BCL10 ALOX12B	4.18e-03	14	206	2	C1336708
Disease	fasting blood glucose measurement	MNX1 DCBLD1 LIN9 ARAP1 FAT3 JMJD1C TPH2	4.18e-03	287	206	7	EFO_0004465
Disease	Meckel-Gruber syndrome	CC2D2A CSPP1	4.80e-03	15	206	2	C0265215
Disease	overall survival, pancreatic carcinoma	RBFOX1 KCNK10 CTNNA2	4.88e-03	49	206	3	EFO_0000638, EFO_0002618
Disease	mean corpuscular hemoglobin concentration	AGO2 STIMATE LIN9 AGO4 HECW2 CC2D2A CDT1 HSF2BP CPS1 SLC4A2 CDCA7 RP1L1 RBFOX1 MACF1 PRKDC EPB41L2	4.88e-03	1105	206	16	EFO_0004528
Disease	heart rate	TAS2R16 SRGAP2C ADAM17 FAM13C HVCN1 RBFOX1	5.13e-03	225	206	6	EFO_0004326
Disease	serum gamma-glutamyl transferase measurement	CDK18 MYO9A RYR2 MET NF1 PKD1 KMT2A SORBS2 SPECC1L CPS1 JMJD1C RP1L1 ROBO1 DCAF4	5.15e-03	914	206	14	EFO_0004532
Disease	suicide	RPS6KC1 HS3ST3B1 RP1L1	5.16e-03	50	206	3	EFO_0007624
Disease	alkaline phosphatase measurement	CYP24A1 KIF9 NF1 SULT2A1 PKD1 ZBTB40 ANAPC4 B4GALNT4 RBL2 CPS1 JMJD1C SLF2 RP1L1 MACF1 SCAI	5.30e-03	1015	206	15	EFO_0004533
Disease	DiGeorge Syndrome	HIRA JMJD1C	5.46e-03	16	206	2	C0012236
Disease	CONOTRUNCAL ANOMALY FACE SYNDROME	HIRA JMJD1C	5.46e-03	16	206	2	C0795907
Disease	Intrahepatic cholestasis of pregnancy	SULT2A1 ENPP7	5.46e-03	16	206	2	EFO_0009048
Disease	lower body strength measurement	KIAA1671 RBFOX1	5.46e-03	16	206	2	EFO_0007999
Disease	N-acetyl-beta-alanine measurement	RYR3 HS3ST3A1	5.46e-03	16	206	2	EFO_0021430
Disease	autosomal recessive polycystic kidney disease (implicated_via_orthology)	PKD1 IFT88	5.46e-03	16	206	2	DOID:0110861 (implicated_via_orthology)
Disease	Shprintzen syndrome	HIRA JMJD1C	5.46e-03	16	206	2	C0220704
Disease	blood cobalt measurement	RBBP8NL SLIT2 CC2D2A USH2A	5.56e-03	101	206	4	EFO_0007577
Disease	age at first sexual intercourse measurement	MRPS30 MET GABPB2 ANAPC4 AMBRA1 FEZF1 RBFOX1 GABPB1	5.70e-03	383	206	8	EFO_0009749
Disease	anti-anoctamin 2 antibody measurement	NEU1 RBFOX1	6.16e-03	17	206	2	EFO_0010150
Disease	non-Hodgkin lymphoma (is_implicated_in)	KMT2A BCL10	6.16e-03	17	206	2	DOID:0060060 (is_implicated_in)
Disease	dermatomyositis (is_marker_for)	SLIT2 ROBO1	6.16e-03	17	206	2	DOID:10223 (is_marker_for)
Disease	Retinitis Pigmentosa	CDHR1 PRPF6 USH2A IFT88	6.16e-03	104	206	4	C0035334
Disease	chronic kidney disease	MRPS30 HS3ST3B1 GPATCH2 GRIN2A CPS1 DCAF4	6.32e-03	235	206	6	EFO_0003884
Disease	body mass index, osteoarthritis	CAMKV CACNA1H ANAPC4	6.40e-03	54	206	3	EFO_0004340, MONDO_0005178
Disease	Meckel syndrome type 1	CC2D2A CSPP1	6.89e-03	18	206	2	C3714506
Disease	Bone marrow hypocellularity	MYSM1 FANCI	6.89e-03	18	206	2	C1855710
Disease	Myeloid Leukemia	AGO2 KMT2A	6.89e-03	18	206	2	C0023470
Disease	Leukemia, Monocytic, Chronic	AGO2 KMT2A	6.89e-03	18	206	2	C0023466

Protein segments in the cluster

Peptide	Gene	Start	Entry
APSFRATEASDSRKM	PI16	216	Q6UXB8
PMVRRAAASKLGEFA	PPP2R1B	191	P30154
PRDRKTFLFSATMTK	DDX47	196	Q9H0S4
IRSMDPSALASDRFN	DCAF4	161	Q8WV16
FLSRPTMAFVRLREA	SLC4A2	526	P04920
SSPDLDRIAASMRAL	AKT1S1	211	Q96B36
TLSRSPMAAFLIQTK	CDHR1	681	Q96JP9
PEVTRMARKFTHISA	ANAPC4	246	Q9UJX5
RRMDAPTSAAVTRAF	AKR7L	21	Q8NHP1
RRMDAPTSAAVTRAF	AKR7A3	21	O95154
APRLGVFTRSMAKKT	CSMD2	2246	Q7Z408
FATPMEAELARRSLA	CTAG1A	96	P78358
ARDMESALRAFATRP	CASP4	181	P49662
RRFSMEDVSKRLSLP	CDK18	86	Q07002
FPFSSALQRMSVVAR	ATP13A3	626	Q9H7F0
ATSEKVGRAMSRAAF	GRM2	236	Q14416
LRSVFVSERKPALSM	CDT1	461	Q9H211
RVPAMESAKTLSVSR	SPECC1L	931	Q69YQ0
LFLSRLRAPFSSMAK	DGUOK	6	Q16854
RSEFKMASSPAVLRA	ACOT2	16	P49753
RPEMLKEETRSSAAA	CUEDC2	116	Q9H467
MAPERLRSRALSAFK	POLE2	1	P56282
LTEPRKAFDMISQRS	GIPC1	211	O14908
MDDAALRAVSRPAAS	DNHD1	3311	Q96M86
TSTMIKATARSAPDR	AGO4	351	Q9HCK5
SRREPFAVVKTASEM	AMBRA1	166	Q9C0C7
AADNRKITPLMAAFR	ANKRD17	1381	O75179
RFRPELKVLVASATM	DHX16	541	O60231
EMLSDPVKRRAFNSV	DNAJC2	146	Q99543
LLTARRMVTAKDSDP	CDAN1	331	Q8IWY9
KLMRSASFNTDPYVR	AGO2	381	Q9UKV8
RPSGDAFIQMKSADR	ESRP1	486	Q6NXG1
KDPSDRTRMSLIFAN	CYB5R2	171	Q6BCY4
AVETFMKLRARDPAS	INTS6	31	Q9UL03
SMPVEAASEALRRLS	PCDH12	1126	Q9NPG4
RMRRTFEEPTSSLAA	KCNG3	156	Q8TAE7
LNKDRTSRDSSPVMR	RBL2	956	Q08999
TLKEADPSSKAAMRR	ANKRD36C	556	Q5JPF3
KLRSSFPTDTRLNAM	HECW2	446	Q9P2P5
SNLKTPITLFRMATA	FBLN7	346	Q53RD9
EKPAAVATAMARVLR	FANCI	1231	Q9NVI1
RMLRFEPSARISAAA	MAPK7	326	Q13164
SAEGRAMSKTLRDFL	PADI6	446	Q6TGC4
PADVSRFAALMSCRS	INKA1	261	Q96EL1
MPASSLESRSFLLAK	PTCD3	96	Q96EY7
DMALDQRFSRLPSKA	NUP98	1006	P52948
VTREAPARISAMSKD	HS3ST3B1	206	Q9Y662
VEMPFRNSKRSRLFS	LIN9	51	Q5TKA1
ERRAPSKDRMIFAAT	MAGEL2	741	Q9UJ55
PRAFLETSKMLVLRF	MAGEL2	1186	Q9UJ55
FNKAVFLRPSSSTMI	KIAA1671	131	Q9BY89
RSKFLASRVMADELT	BLZF1	216	Q9H2G9
SRSKNSPMEFFRIDS	RPS6KC1	591	Q96S38
SRSPMDTFLLIKERA	LILRB4	146	Q8NHJ6
MFKDFAARSPSASIT	PPFIBP1	991	Q86W92
LSRPKRFEVATSLML	MNX1	266	P50219
APAERMSKFLRHFTV	HVCN1	16	Q96D96
FNDMFIRISTRLPSK	MGAM	2011	O43451
KAFMEPLRSVASTSA	JMJD1C	961	Q15652
ARTKVDRTPLHMAAS	GABPB1	66	Q06547
AVPMAVLSRRESSLA	BEND2	256	Q8NDZ0
RLASFPFTKTGMLSR	C20orf203	31	Q8NBC4
VIMRALFESKTPSAL	DDX59	261	Q5T1V6
PVLASMTKAADPRFR	CANT1	26	Q8WVQ1
ASISELKRNFMESTP	EPB41L2	646	O43491
PRRRAASMDSSSKLL	FOXO4	191	P98177
SFKRDRAPFVLTSDM	PIK3C2A	1281	O00443
RMPRDDTSDFLKNSL	CSPP1	1081	Q1MSJ5
LRMKNFETSTLSFSP	HAO1	181	Q9UJM8
PKRVKARFSTASDMR	KDM4C	991	Q9H3R0
KTFRPAAMLIERSSD	LAMB1	141	P07942
TFKTFRPAAMLVERS	LAMB2	151	P55268
LRSEAMSSVAAKVRA	NSMF	11	Q6X4W1
ELALRMSTANTDPFK	TUBGCP2	556	Q9BSJ2
VTREAPARISAMSKD	HS3ST3A1	221	Q9Y663
MLSPEKRSVFAALDT	KCNK10	391	P57789
STIKQFPASRLARML	KCNRG	21	Q8N5I3
AKELSMVRIPSRAAA	ASIC3	376	Q9UHC3
DLMIAFESRKRAAAP	HSPA12A	381	O43301
LRFASRMKLVTTEPA	KIF9	331	Q9HAQ2
PRSSSRMEERLKAAN	GATAD2B	136	Q8WXI9
AMRKLSFADEVTTSP	INSM2	221	Q96T92
RSVPSEKLTTAMNRF	MLKL	51	Q8NB16
MKANSFESRLTPSRF	RICTOR	1366	Q6R327
FESRLTPSRFMKALS	RICTOR	1371	Q6R327
REHEMKRAVTSLPFT	PHOSPHO2	61	Q8TCD6
RAPDSSSEFGKVTRM	GPR84	306	Q9NQS5
KMSEPLIRRSSFSDR	MEDAG	241	Q5VYS4
SGTKTALMDRLRPFQ	MYOCD	391	Q8IZQ8
RKPMTRAELVAISSS	MACF1	566	Q9UPN3
MSLDRSLAVARPFVS	LTB4R	111	Q15722
TKRRQMAADLLASAP	NKX3-2	261	P78367
LSLDSFLRASRPSAM	RBBP8NL	261	Q8NC74
PNRETLMDLSTKAFA	CPS1	601	P31327
RANIRRAFTEMTPSF	DNAH6	3661	Q9C0G6
ASGLFPAEMRERTTK	FBXL19-AS1	91	Q494R0
ASHRRPVSANKEMFS	FHAD1	161	B1AJZ9
VTRPMTAVRAAGFTK	IFT88	91	Q13099
KFATDRTSMPSANII	BMP10	91	O95393
RTSMPSANIIRSFKN	BMP10	96	O95393
PSRSSRMFSEKHAAS	CC2D2A	1066	Q9P2K1
TLMKRLRAPEQSSTA	CAMKV	321	Q8NCB2
FTDLSSMDLIRPRVS	DOCK5	281	Q9H7D0
DLFKFLADMRRPSSL	DOCK6	471	Q96HP0
MATLPSAERRAFALK	DOCK8	1	Q8NF50
KIILDPMTFSEARFR	CTNNA2	286	P26232
MSSPISKSRSLAAFL	CYP24A1	1	Q07973
ASDSDPMRQRFSIKA	CPLANE1	391	Q9H799
RNLKTSDPTMSSFRV	COL12A1	1091	Q99715
ANSSEMFLPLRSRTV	BCL10	216	O95999
LMESPISDRTRNTFK	DNAH7	1876	Q8WXX0
IDSISMRKFRIDPST	FAT3	1501	Q8TDW7
SLLPSESHRRFNMEK	CEP350	1626	Q5VT06
PMTSSFRKELDARIF	ANKMY1	181	Q9P2S6
MRVAFSAARTSNLAP	CAPRIN2	996	Q6IMN6
KTASFFVRLGPMALA	ALOX12B	206	O75342
FRSLAMTKPDRQLIA	DYNC1H1	2036	Q14204
VQLKSARRATSMDLP	KMT2A	3801	Q03164
LTFKTFRPAAMLVER	LAMB4	131	A4D0S4
ALKARTTINFSRMPI	FAM172BP	336	A6NC97
LPRLSAFLSNMKSRS	FAAH	426	O00519
PMKAFDSRFTERSKA	HIRA	561	P54198
VTRKGSTFRPMDTDA	DCBLD1	551	Q8N8Z6
DSDDQMLVAKRRPSS	GPATCH2	116	Q9NW75
RPRKLFMQTVSSDDS	FAM216A	226	Q8WUB2
DMKTIFRAVGPSFRA	ENPP7	361	Q6UWV6
LPAQRQMSRFKEAST	GPRIN3	286	Q6ZVF9
LRFESTMKRDPTAEQ	CASP14	46	P31944
ARKVSVSRMLSLPND	CACNA1H	1916	O95180
ALFNTAMTKATPAVR	DENND1B	431	Q6P3S1
RAVSPFAKIRSSMVQ	INPP5F	1066	Q9Y2H2
IKAFSMTAAETARRT	RYR1	1981	P21817
FLPDMRAAASLDTAT	RYR1	2526	P21817
PRMAFFSILTVRSAL	RYR2	4231	Q92736
LDRSADSPSFRKSRM	MAP3K3	231	Q99759
DSPSFRKSRMSRAQS	MAP3K3	236	Q99759
LFLFRMSRSKVAGSP	PKD1	3341	P98161
PASTKQADRRQSMAF	NUMA1	2036	Q14980
ARTKVDRTPLHMAAA	GABPB2	66	Q8TAK5
MRPSFSELVSRISAI	MET	1326	P08581
PIVASMTADSKAARL	MRPS30	46	Q9NP92
NPSMKARFTALRSLA	TAS2R16	216	Q9NYV7
FRSSLPLQRILAMSK	HSF2BP	296	O75031
PRSHSMRFIDKTSAL	USH2A	2676	O75445
AMNAFAPLTDAKTRS	RBFOX1	356	Q9NWB1
KSMSAPVIFDRSREE	SNX2	116	O60749
PSDVRGMTKLDRTAF	TRMT5	76	Q32P41
KSAFTRVASMVSLQP	SPAG5	946	Q96R06
KSRSRNLSMDSLVVP	TMEM200A	316	Q86VY9
FMRAASVLKSLPFTI	DNTT	191	P04053
RSRASSSKFPLMTLQ	LAPTM5	126	Q13571
AKARSSAPTARVFMK	PRPF6	666	O94906
SKPLAFSIERIMART	FEZF1	26	A0PJY2
QRDFTAAFPRMLTTR	HAVCR2	141	Q8TDQ0
LMPFRLSSKSVDSFL	SLC9A3	801	P48764
PRGTLLAFAEARKMS	NEU1	86	Q99519
SSDEGAKFIALRRSM	NEU1	101	Q99519
ENIPEDSSMVSKRFR	STK17B	341	O94768
FMLSVPFVASSAALR	SSTR4	96	P31391
TSFQRKELRMSLPAR	SHROOM1	156	Q2M3G4
RSAMPLRDAAKLAVT	SLC39A3	221	Q9BRY0
VSETFMSKPSIAKRR	SRGAP2C	426	P0DJJ0
SETFMSKPSIAKRRA	SRGAP2B	426	P0DMP2
KSTRESMIPKARESF	SLF2	346	Q8IX21
RFSRALMAAKRSSGA	SPAST	81	Q9UBP0
IAFPTMGFRSETLRK	SULT2A1	11	Q06520
VDSVLRPSMGNFKSR	FAM13C	76	Q8NE31
SASMASDFRKRRKSE	SORBS2	246	O94875
SRSSRMLAVFPANGK	SCN1A	626	P35498
MSREPFSTRALVLSI	SOAT2	326	O75908
SMSAATARRPVFDDK	STK32C	71	Q86UX6
FSSQVSKPRRLMASR	B4GALNT4	226	Q76KP1
LSSMDSASVRIIKPF	ADAM17	716	P78536
EMRRSVAAFTADPLS	ARAP1	1431	Q96P48
RVAMKFPARSTRGAT	CDCA7	71	Q9BWT1
RRSAQDPTMLQFKST	CGN	281	Q9P2M7
RDPRAVLASRMVAFA	CHST3	301	Q7LGC8
FSMRKVPNREATEIS	CLTRN	56	Q9HBJ8
PAALRVSSQRKDFME	TNRC18	2886	O15417
SNLRAKMYSIEPADR	UBA6	866	A0AVT1
STKLRPAAAARAMDP	STK35	161	Q8TDR2
ASLGIAFSRSRAVMK	ZNF671	86	Q8TAW3
MLRRVALKNVDSSPS	TLR3	486	O15455
RSSRVPNDDMDIFSK	nan	131	Q6ZSR9
MPARTVLFTNARKFD	MTREX	491	P42285
MFSRATSLPDIAKTA	SPATA46	26	Q5T0L3
IESPEKRRMATFGSA	SRGAP3	906	O43295
MTTFKPALSARLAGA	SRGAP3	1036	O43295
RTPAMKNARRSEAET	RP1L1	226	Q8IWN7
FLQRRPSMKTLFVDS	TRPV1	496	Q8NER1
FRHSQPRSKSEMLSR	ILDR2	401	Q71H61
NAMPLSAAIFRSEEK	RYR3	1466	Q15413
RDKDRSATVSSSVPM	SPATA20	31	Q8TB22
MAADSARSFSPLEKF	SRL	151	Q86TD4
RSAPEAASMLAAELR	SCARF2	766	Q96GP6
VSETFMSKPSIAKRR	SRGAP2	426	O75044
PFRASLTKMESTALL	nan	31	Q9UF83
DTKPTRAAMLRAISQ	VWA2	586	Q5GFL6
NADTPVSKFMDRLLS	NF1	886	P21359
SFPTADLTLKMESAR	PRRC2B	1846	Q5JSZ5
RSRTEFALKEIMSSG	SCAI	31	Q8N9R8
SVASFNHMPKLRTFR	SLIT2	191	O94813
FRKLLMTPRAAPTSA	IK	36	Q13123
LPSMDARTDRSSDRK	ROBO1	1511	Q9Y6N7
VVAFSTLMLKRFREP	STIMATE	46	Q86TL2
PQSSDEVKAARRSML	RPAP1	1321	Q9BWH6
PFVQALKARMTSFHR	USB1	136	Q9BQ65
LVASFSERVRNMSPD	SAP30BP	101	Q9UHR5
KMRDFAKSITRPFSV	TPH2	431	Q8IWU9
DLLKRAFVRMSTSPE	PRKDC	3881	P78527
AFVRMSTSPEAFLAL	PRKDC	3886	P78527
KNMRSPIATIRTDSA	WDR37	396	Q9Y2I8
MASSASARTPAGKRV	ZNF830	1	Q96NB3
KDRFSAEMPDATLAT	TRBV12-5	81	A0A1B0GX78
MSSNVPHERVFKASR	TMC2	676	Q8TDI7
LMSSVPKRASRYDVT	UGGT2	931	Q9NYU1
HPTAATKMSRALAEF	PC	436	P11498
RDRVHKFTSDSPMAA	SMTN	331	P53814
SPEASLRAVLSRAME	ZBTB40	621	Q9NUA8
LRAVLSRAMEKSVPA	ZBTB40	626	Q9NUA8
PDALTMFSRLKASES	UBALD1	76	Q8TB05
ALKPFEAASREMSTQ	ZBED4	936	O75132
ASDSDIRPQRAKMRF	MYO9A	1746	B2RTY4
HSSVPMDKIFRRDSD	MYSM1	756	Q5VVJ2
NSSRMDSPKRAADFI	GRIN2A	911	Q12879