Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	L-leucine binding	SESN3 SESN1 SESN2	1.45e-05	7	151	3	GO:0070728
GeneOntologyBiologicalProcess	cell-substrate junction assembly	ENPP2 ITGA6 DST TESK2 MACF1 MAP4K4 SMAD3	1.41e-05	108	150	7	GO:0007044
GeneOntologyBiologicalProcess	cell-substrate junction organization	ENPP2 ITGA6 DST TESK2 MACF1 MAP4K4 SMAD3	2.13e-05	115	150	7	GO:0150115
GeneOntologyBiologicalProcess	intracellular transport	SNF8 VPS11 TPCN2 GBF1 CRACR2A KIF1A SYNE1 GRAMD1A LRRK2 DYNC2I1 IPO4 ALS2CL DENND1A B3GAT3 TBC1D10B ARSB DST MDN1 SYNE2 LRP6 AKAP13 TRAPPC9 SEC23B SMAD3 DOP1B	7.67e-05	1496	150	25	GO:0046907
GeneOntologyBiologicalProcess	cellular response to leucine starvation	SESN3 SESN1 SESN2	7.90e-05	12	150	3	GO:1990253
GeneOntologyBiologicalProcess	response to reactive oxygen species	TRPA1 GPR37 LRRK2 SESN3 SESN1 STAT1 BTK FER SESN2	8.13e-05	246	150	9	GO:0000302
GeneOntologyBiologicalProcess	positive regulation of molecular function	CAB39 CRACR2A HIPK1 SPTA1 LRRK2 ITGA6 TLR9 DENND1A STAT1 B3GAT3 TBC1D10B TCL1A BTK RXFP2 FER LRP6 SESN2 CDT1 PIH1D1 MAP4K4 TSSK4 TRAPPC9 SMAD3 CRTC2	1.02e-04	1430	150	24	GO:0044093
GeneOntologyBiologicalProcess	regulation of response to reactive oxygen species	SESN3 SESN1 SESN2	1.02e-04	13	150	3	GO:1901031
GeneOntologyBiologicalProcess	cellular response to L-leucine	SESN3 SESN1 SESN2	1.02e-04	13	150	3	GO:0071233
GeneOntologyBiologicalProcess	regulation of plasma membrane bounded cell projection organization	DCDC2 KIF1A ENPP2 DISC1 SYNE1 LRRK2 ITGA6 SYNGAP1 TBC1D10B NEO1 ARSB SYNE2 FER LRP6 MACF1 MAP4K4 CEP97	1.46e-04	846	150	17	GO:0120035
GeneOntologyBiologicalProcess	establishment of organelle localization	SNF8 GBF1 KIF1A EML4 SYNE1 LRRK2 MDN1 PIK3CD ABRAXAS1 BTK SYNE2 CDT1 TRAPPC9	1.83e-04	546	150	13	GO:0051656
GeneOntologyBiologicalProcess	regulation of cell projection organization	DCDC2 KIF1A ENPP2 DISC1 SYNE1 LRRK2 ITGA6 SYNGAP1 TBC1D10B NEO1 ARSB SYNE2 FER LRP6 MACF1 MAP4K4 CEP97	1.85e-04	863	150	17	GO:0031344
GeneOntologyBiologicalProcess	organelle localization	SNF8 RABEPK VPS11 GBF1 KIF1A EML4 SYNE1 LRRK2 MDN1 PIK3CD ABRAXAS1 BTK SYNE2 CDT1 TRAPPC9	1.93e-04	703	150	15	GO:0051640
GeneOntologyBiologicalProcess	response to L-leucine	SESN3 SESN1 SESN2	1.97e-04	16	150	3	GO:0043201
GeneOntologyCellularComponent	GATOR2 complex	SESN3 SESN1 SESN2	8.22e-05	12	154	3	GO:0061700
GeneOntologyCellularComponent	Wnt signalosome	LRRK2 ADGRA2 LRP6	2.05e-04	16	154	3	GO:1990909
GeneOntologyCellularComponent	Seh1-associated complex	SESN3 SESN1 SESN2	2.05e-04	16	154	3	GO:0035859
GeneOntologyCellularComponent	supramolecular fiber	LRRC39 CAB39 VPS11 DCDC2 KRT13 KIF1A EML4 DISC1 SYNE1 MYOM3 TMEM214 DST SYNJ2 TTLL6 SYNE2 MACF1 AKAP13 DNAH9 PLS3 TTLL13	4.25e-04	1179	154	20	GO:0099512
GeneOntologyCellularComponent	supramolecular polymer	LRRC39 CAB39 VPS11 DCDC2 KRT13 KIF1A EML4 DISC1 SYNE1 MYOM3 TMEM214 DST SYNJ2 TTLL6 SYNE2 MACF1 AKAP13 DNAH9 PLS3 TTLL13	4.63e-04	1187	154	20	GO:0099081
MousePheno	increased chromosomal stability	ZSCAN5A ZSCAN5B ZSCAN5C	1.18e-05	6	119	3	MP:0010095
Domain	SCAN	ZSCAN5A ZSCAN9 ZNF215 ZSCAN5B ZSCAN10 ZSCAN30 ZSCAN5C ZNF287	1.72e-08	56	153	8	SM00431
Domain	SCAN_BOX	ZSCAN5A ZSCAN9 ZNF215 ZSCAN5B ZSCAN10 ZSCAN30 ZSCAN5C ZNF287	2.29e-08	58	153	8	PS50804
Domain	SCAN	ZSCAN5A ZSCAN9 ZNF215 ZSCAN5B ZSCAN10 ZSCAN30 ZSCAN5C ZNF287	2.29e-08	58	153	8	PF02023
Domain	SCAN_dom	ZSCAN5A ZSCAN9 ZNF215 ZSCAN5B ZSCAN10 ZSCAN30 ZSCAN5C ZNF287	2.29e-08	58	153	8	IPR003309
Domain	Retrov_capsid_C	ZSCAN5A ZSCAN9 ZNF215 ZSCAN5B ZSCAN10 ZSCAN30 ZSCAN5C ZNF287	2.63e-08	59	153	8	IPR008916
Domain	Sestrin	SESN3 SESN1 SESN2	5.39e-07	3	153	3	IPR006730
Domain	AhpD-like	SESN3 SESN1 SESN2	5.39e-07	3	153	3	IPR029032
Domain	PA26	SESN3 SESN1 SESN2	5.39e-07	3	153	3	PF04636
Domain	-	SESN3 SESN1 SESN2	5.39e-07	3	153	3	1.20.1290.10
Domain	Spectrin	SYNE1 SPTA1 DST SYNE2 MACF1	1.03e-06	23	153	5	PF00435
Domain	ACTININ_2	SYNE1 DST SYNE2 MACF1 PLS3	1.03e-06	23	153	5	PS00020
Domain	ACTININ_1	SYNE1 DST SYNE2 MACF1 PLS3	1.03e-06	23	153	5	PS00019
Domain	Actinin_actin-bd_CS	SYNE1 DST SYNE2 MACF1 PLS3	1.03e-06	23	153	5	IPR001589
Domain	Spectrin_repeat	SYNE1 SPTA1 DST SYNE2 MACF1	3.50e-06	29	153	5	IPR002017
Domain	SPEC	SYNE1 SPTA1 DST SYNE2 MACF1	5.82e-06	32	153	5	SM00150
Domain	Spectrin/alpha-actinin	SYNE1 SPTA1 DST SYNE2 MACF1	5.82e-06	32	153	5	IPR018159
Domain	LRR	LRRC39 LRRIQ3 LRRC32 LRRK2 TLR9 ADGRA2 PXDN RXFP2 LINGO4 CEP97	6.29e-06	201	153	10	PS51450
Domain	Leu-rich_rpt_4	LRRC39 LRRIQ3 LRRK2	6.20e-05	10	153	3	IPR025875
Domain	LRR_4	LRRC39 LRRIQ3 LRRK2	6.20e-05	10	153	3	PF12799
Domain	Leu-rich_rpt	LRRC39 LRRIQ3 LRRC32 LRRK2 TLR9 ADGRA2 PXDN RXFP2 LINGO4 CEP97	8.14e-05	271	153	10	IPR001611
Domain	LRR_1	LRRC39 LRRC32 LRRK2 TLR9 ADGRA2 PXDN RXFP2 LINGO4 CEP97	8.23e-05	219	153	9	PF00560
Domain	LRR_8	LRRC39 LRRC32 LRRK2 TLR9 ADGRA2 PXDN RXFP2 LINGO4	8.41e-05	171	153	8	PF13855
Domain	LRR_TYP	LRRC39 LRRC32 LRRK2 TLR9 ADGRA2 PXDN RXFP2 LINGO4	1.07e-04	177	153	8	SM00369
Domain	Leu-rich_rpt_typical-subtyp	LRRC39 LRRC32 LRRK2 TLR9 ADGRA2 PXDN RXFP2 LINGO4	1.07e-04	177	153	8	IPR003591
Domain	CH	SYNE1 DST SYNE2 MACF1 PLS3	1.92e-04	65	153	5	SM00033
Domain	RTT107_BRCT_5	MDC1 PAXIP1	1.99e-04	3	153	2	PF16770
Domain	CH	SYNE1 DST SYNE2 MACF1 PLS3	2.72e-04	70	153	5	PF00307
Domain	-	SYNE1 DST SYNE2 MACF1 PLS3	2.91e-04	71	153	5	1.10.418.10
Domain	-	LRRC39 LRRIQ3 LRRC32 LRRK2 TLR9 ADGRA2 PXDN RXFP2 LINGO4 CEP97	3.21e-04	321	153	10	3.80.10.10
Domain	CH	SYNE1 DST SYNE2 MACF1 PLS3	3.31e-04	73	153	5	PS50021
Domain	CH-domain	SYNE1 DST SYNE2 MACF1 PLS3	3.76e-04	75	153	5	IPR001715
Domain	L_dom-like	LRRC39 LRRIQ3 LRRC32 LRRK2 TLR9 ADGRA2 PXDN RXFP2 LINGO4 CEP97	3.81e-04	328	153	10	IPR032675
Domain	KASH	SYNE1 SYNE2	3.96e-04	4	153	2	IPR012315
Domain	KASH	SYNE1 SYNE2	3.96e-04	4	153	2	PS51049
Domain	KASH	SYNE1 SYNE2	3.96e-04	4	153	2	SM01249
Domain	KASH	SYNE1 SYNE2	3.96e-04	4	153	2	PF10541
Domain	ARM-type_fold	DOCK2 CAB39 USP34 VPS11 GBF1 LRRK2 IPO4 FOCAD PSME4 PIK3CD	4.93e-04	339	153	10	IPR016024
Domain	Kinase-like_dom	HIPK1 SPEG LRRK2 GRK1 DST PIK3CD TESK2 BTK ETNK2 FER MACF1 MAP4K4 TSSK4	5.30e-04	542	153	13	IPR011009
Domain	EF-hand_7	CRACR2A CETN3 DST MACF1 PLS3	6.69e-04	85	153	5	PF13499
Domain	-	DST MACF1	9.79e-04	6	153	2	3.90.1290.10
Domain	GAR	DST MACF1	9.79e-04	6	153	2	PS51460
Domain	GAS2	DST MACF1	9.79e-04	6	153	2	PF02187
Domain	-	DST MACF1	9.79e-04	6	153	2	3.30.920.20
Domain	GAS_dom	DST MACF1	9.79e-04	6	153	2	IPR003108
Domain	GAS2	DST MACF1	9.79e-04	6	153	2	SM00243
Domain	Plectin	DST MACF1	1.36e-03	7	153	2	PF00681
Domain	Plectin_repeat	DST MACF1	1.36e-03	7	153	2	IPR001101
Domain	PLEC	DST MACF1	1.36e-03	7	153	2	SM00250
Domain	EFh	CRACR2A CETN3 SPTA1 DST MACF1 PLS3	1.94e-03	158	153	6	SM00054
Domain	SH3	DOCK2 MACC1 MYO7B SPTA1 DST BTK MACF1	2.05e-03	216	153	7	PS50002
Domain	SH3_domain	DOCK2 MACC1 MYO7B SPTA1 DST BTK MACF1	2.27e-03	220	153	7	IPR001452
Domain	DUF1220	NBPF4 NBPF6	2.31e-03	9	153	2	SM01148
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	GBF1 TEX2 WDR26 DENND1A USP31 TBC1D10B DST MDN1 SYNJ2 TESK2 SYNE2 KMT2A MACF1 AKAP13 RASSF8 MAP4K4 TRAPPC9 SEC23B CRTC2 DOP1B	2.67e-09	861	158	20	36931259
Pubmed	Sestrin1, 2, and 3 are dispensable for female fertility in mice.	SESN3 SESN1 SESN2	9.20e-08	3	158	3	38297375
Pubmed	PA26 is a candidate gene for heterotaxia in humans: identification of a novel PA26-related gene family in human and mouse.	SESN3 SESN1 SESN2	9.20e-08	3	158	3	12607115
Pubmed	Sestrins are evolutionarily conserved mediators of exercise benefits.	SESN3 SESN1 SESN2	9.20e-08	3	158	3	31929512
Pubmed	Circulating Sestrin Levels Are Increased in Hypertension Patients.	SESN3 SESN1 SESN2	9.20e-08	3	158	3	32626541
Pubmed	Interactions between microRNA-200 family and Sestrin proteins in endometrial cancer cell lines and their significance to anoikis.	SESN3 SESN1 SESN2	9.20e-08	3	158	3	31073887
Pubmed	The functions and roles of sestrins in regulating human diseases.	SESN3 SESN1 SESN2	9.20e-08	3	158	3	34979914
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	USP34 GBF1 SPEG MYOM3 SFI1 HES2 ADGRA2 DENND1A ITPR3 FOCAD ORC1 DST MDN1 PSME4 PIK3CD CSAD PAXIP1 AKAP13 ZFYVE26 TRAPPC9	1.61e-07	1105	158	20	35748872
Pubmed	Zscan5b Deficiency Impairs DNA Damage Response and Causes Chromosomal Aberrations during Mitosis.	ZSCAN5A ZSCAN5B ZSCAN5C	3.67e-07	4	158	3	31155506
Pubmed	ZSCAN5B and primate-specific paralogs bind RNA polymerase III genes and extra-TFIIIC (ETC) sites to modulate mitotic progression.	ZSCAN5A ZSCAN5B ZSCAN5C	3.67e-07	4	158	3	27732952
Pubmed	Maintenance of metabolic homeostasis by Sestrin2 and Sestrin3.	SESN3 SESN1 SESN2	3.67e-07	4	158	3	22958918
Pubmed	Sestrin2 is a leucine sensor for the mTORC1 pathway.	SESN3 SESN1 SESN2	9.14e-07	5	158	3	26449471
Pubmed	Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.	USP34 DCDC2 GBF1 SYNE1 ADGRA2 DST SYNE2 MACF1 DOP1B	9.85e-07	225	158	9	12168954
Pubmed	Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.	USP34 KIF1A PRPF6 IPO4 ITPR3 DST MDN1 GTF3C1 ATAD2B MDC1 SYNE2 KMT2A MACF1 SEC23B	1.89e-06	653	158	14	22586326
Pubmed	Protein interactome mining defines melatonin MT1 receptors as integral component of presynaptic protein complexes of neurons.	USP34 COMT PKD1L2 IPO4 ITPR3 DST PSME4 SYNE2 PAXIP1 MACF1	2.40e-06	322	158	10	26514267
Pubmed	A human MAP kinase interactome.	KRT13 HIPK1 SYNE1 STAT1 DST SYNJ2 BTK MACF1 AKAP13 YY1AP1 COG5 MAP4K4	2.53e-06	486	158	12	20936779
Pubmed	Sestrins function as guanine nucleotide dissociation inhibitors for Rag GTPases to control mTORC1 signaling.	SESN3 SESN1 SESN2	3.18e-06	7	158	3	25259925
Pubmed	VCP phosphorylation-dependent interaction partners prevent apoptosis in Helicobacter pylori-infected gastric epithelial cells.	CAB39 GBF1 COMT STAT1 TBC1D10B MDN1 GTF3C1 SESN2 COG5	7.39e-06	288	158	9	23383273
Pubmed	E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins.	KIF1A GPR37 DISC1 MYOM3 RNF213 FOCAD FRY ARHGEF33 DST MDN1 GTF3C1 ATAD2B AKAP13 DOP1B	7.42e-06	736	158	14	29676528
Pubmed	Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein.	EML4 TBC1D10B DST PSME4 GTF3C1 SHCBP1 KMT2A AKAP13 YY1AP1 GALNT6 MAP4K4 SEC23B CRTC2	9.38e-06	650	158	13	38777146
Pubmed	The role of microtubule actin cross-linking factor 1 (MACF1) in the Wnt signaling pathway.	DST LRP6 MACF1	1.48e-05	11	158	3	16815997
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	HIPK1 SYNE1 SPEG FOCAD USP31 PXDN ACOT11 MACF1 YY1AP1 DOP1B	1.85e-05	407	158	10	12693553
Pubmed	The Sestrins interact with GATOR2 to negatively regulate the amino-acid-sensing pathway upstream of mTORC1.	SESN3 SESN1 SESN2	1.96e-05	12	158	3	25263562
Pubmed	Combination of the MEK inhibitor pimasertib with BTK or PI3K-delta inhibitors is active in preclinical models of aggressive lymphomas.	PIK3CD BTK	2.05e-05	2	158	2	26961147
Pubmed	The Bruton Tyrosine Kinase (BTK) Inhibitor Acalabrutinib Demonstrates Potent On-Target Effects and Efficacy in Two Mouse Models of Chronic Lymphocytic Leukemia.	TCL1A BTK	2.05e-05	2	158	2	27903679
Pubmed	Common variants in psychiatric risk genes predict brain structure at birth.	COMT DISC1	2.05e-05	2	158	2	23283688
Pubmed	Nesprins: a novel family of spectrin-repeat-containing proteins that localize to the nuclear membrane in multiple tissues.	SYNE1 SYNE2	2.05e-05	2	158	2	11792814
Pubmed	Acf7 (MACF) is an actin and microtubule linker protein whose expression predominates in neural, muscle, and lung development.	DST MACF1	2.05e-05	2	158	2	11002341
Pubmed	TORC2 regulates germinal center repression of the TCL1 oncoprotein to promote B cell development and inhibit transformation.	TCL1A CRTC2	2.05e-05	2	158	2	17548807
Pubmed	Nesprin-1 and nesprin-2 regulate endothelial cell shape and migration.	SYNE1 SYNE2	2.05e-05	2	158	2	24931616
Pubmed	Effects of age, genes, and pulse pressure on executive functions in healthy adults.	COMT ACE	2.05e-05	2	158	2	19559505
Pubmed	Autophagosome-lysosome fusion triggers a lysosomal response mediated by TLR9 and controlled by OCRL.	OCRL TLR9	2.05e-05	2	158	2	27398910
Pubmed	A crucial role for the p110delta subunit of phosphatidylinositol 3-kinase in B cell development and activation.	PIK3CD BTK	2.05e-05	2	158	2	12235209
Pubmed	Sestrin as a feedback inhibitor of TOR that prevents age-related pathologies.	SESN1 SESN2	2.05e-05	2	158	2	20203043
Pubmed	SESN3 Inhibited SMAD3 to Relieve Its Suppression for MiR-124, Thus Regulating Pre-Adipocyte Adipogenesis.	SESN3 SMAD3	2.05e-05	2	158	2	34946801
Pubmed	Interaction between angiotensin-converting enzyme and catechol-O-methyltransferase genotypes in schizophrenics with poor response to conventional neuroleptics.	COMT ACE	2.05e-05	2	158	2	12729939
Pubmed	Combined BTK and PI3Kδ Inhibition with Acalabrutinib and ACP-319 Improves Survival and Tumor Control in CLL Mouse Model.	PIK3CD BTK	2.05e-05	2	158	2	28645939
Pubmed	FGF23-induced hypophosphatemia persists in Hyp mice deficient in the WNT coreceptor Lrp6.	PHEX LRP6	2.05e-05	2	158	2	23652555
Pubmed	HGK-sestrin 2 signaling-mediated autophagy contributes to antitumor efficacy of Tanshinone IIA in human osteosarcoma cells.	SESN2 MAP4K4	2.05e-05	2	158	2	30258193
Pubmed	Multiple novel nesprin-1 and nesprin-2 variants act as versatile tissue-specific intracellular scaffolds.	SYNE1 SYNE2	2.05e-05	2	158	2	22768332
Pubmed	Bruton tyrosine kinase mediates TLR9-dependent human dendritic cell activation.	TLR9 BTK	2.05e-05	2	158	2	24612681
Pubmed	Zonated leucine sensing by Sestrin-mTORC1 in the liver controls the response to dietary leucine.	SESN1 SESN2	2.05e-05	2	158	2	35771919
Pubmed	Cardioprotective roles of sestrin 1 and sestrin 2 against doxorubicin cardiotoxicity.	SESN1 SESN2	2.05e-05	2	158	2	31026186
Pubmed	Defective Toll-like receptor 9-mediated cytokine production in B cells from Bruton's tyrosine kinase-deficient mice.	TLR9 BTK	2.05e-05	2	158	2	17725607
Pubmed	Syne-1 and Syne-2 play crucial roles in myonuclear anchorage and motor neuron innervation.	SYNE1 SYNE2	2.05e-05	2	158	2	17267447
Pubmed	Dysregulation of lysosomal morphology by pathogenic LRRK2 is corrected by TPC2 inhibition.	TPCN2 LRRK2	2.05e-05	2	158	2	25416817
Pubmed	Nesprins: tissue-specific expression of epsilon and other short isoforms.	SYNE1 SYNE2	2.05e-05	2	158	2	24718612
Pubmed	Targeted ablation of nesprin 1 and nesprin 2 from murine myocardium results in cardiomyopathy, altered nuclear morphology and inhibition of the biomechanical gene response.	SYNE1 SYNE2	2.05e-05	2	158	2	24586179
Pubmed	Parkinson's disease-associated receptor GPR37 is an ER chaperone for LRP6.	GPR37 LRP6	2.05e-05	2	158	2	28341812
Pubmed	Nesprin-1 and -2 are involved in the pathogenesis of Emery Dreifuss muscular dystrophy and are critical for nuclear envelope integrity.	SYNE1 SYNE2	2.05e-05	2	158	2	17761684
Pubmed	Fbxl18 targets LRRK2 for proteasomal degradation and attenuates cell toxicity.	LRRK2 FBXL18	2.05e-05	2	158	2	27890708
Pubmed	Nesprin-1-alpha2 associates with kinesin at myotube outer nuclear membranes, but is restricted to neuromuscular junction nuclei in adult muscle.	SYNE1 SYNE2	2.05e-05	2	158	2	31578382
Pubmed	Association between plasma activities of semicarbazide-sensitive amine oxidase and angiotensin-converting enzyme in patients with type 1 diabetes mellitus.	ACE AOC3	2.05e-05	2	158	2	15830186
Pubmed	Sestrins orchestrate cellular metabolism to attenuate aging.	SESN3 SESN2	2.05e-05	2	158	2	24055102
Pubmed	[A study of recombinant human sestrin 1 and sestrin 2 proteins produced in a prokaryotic system].	SESN1 SESN2	2.05e-05	2	158	2	28707664
Pubmed	DOCK2 and phosphoinositide-3 kinase δ mediate two complementary signaling pathways for CXCR5-dependent B cell migration.	DOCK2 PIK3CD	2.05e-05	2	158	2	36341455
Pubmed	Protective LRRK2 R1398H Variant Enhances GTPase and Wnt Signaling Activity.	LRRK2 LRP6	2.05e-05	2	158	2	27013965
Pubmed	CD49f protein expression varies among genetic subgroups of B lymphoblastic leukemia and is distinctly low in KMT2A-rearranged cases.	ITGA6 KMT2A	2.05e-05	2	158	2	31894899
Pubmed	Sestrins induce natural killer function in senescent-like CD8+ T cells.	SESN3 SESN1	2.05e-05	2	158	2	32231301
Pubmed	C5orf51 is a component of the MON1-CCZ1 complex and controls RAB7A localization and stability during mitophagy.	GBF1 KIF1A TEX2 GRAMD1A ITGA6 TMEM214 ITPR3 NEO1 DST SYNE2 DOP1B	2.11e-05	504	158	11	34432599
Pubmed	Characterization of the EGFR interactome reveals associated protein complex networks and intracellular receptor dynamics.	GBF1 RNF213 IPO4 WDR26 STAT1 COG5 DOP1B	2.17e-05	183	158	7	23956138
Pubmed	Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.	USP34 KIF1A ENPP2 HIPK1 SYNE1 SESN3 DYNC2I1 WDR26 GTF3C4 STAT1 SYNGAP1 FOCAD FRY DST MACF1 YY1AP1 MAP4K4 DOP1B	2.38e-05	1285	158	18	35914814
Pubmed	Menin and Menin-Associated Proteins Coregulate Cancer Energy Metabolism.	RNF213 PRPF6 GTF3C1 MDC1 UBXN7 PAXIP1 PUS1 KMT2A YY1AP1	2.81e-05	341	158	9	32971831
Pubmed	Multilevel proteomics reveals host perturbations by SARS-CoV-2 and SARS-CoV.	USP34 VPS11 GBF1 RETREG2 COMT EML4 GPR37 ITGA6 RNF213 TMEM214 STEAP2 B3GAT3 FOCAD NEO1 MDN1 MACF1	2.89e-05	1061	158	16	33845483
Pubmed	Association of gene polymorphisms with chronic kidney disease in Japanese individuals.	MYO7B COL23A1 PXDN TRAPPC9	2.98e-05	39	158	4	19724895
Pubmed	A protein-interaction network of interferon-stimulated genes extends the innate immune system landscape.	USP34 GRAMD1A RNF213 PRPF6 IPO4 WDR26 DENND1A ITPR3 LIPT1 DST MDN1 PXDN GTF3C1 MDC1 SYNE2 KMT2A COG5 PLS3 TRAPPC9	3.15e-05	1440	158	19	30833792
Pubmed	A pilot multivariate parallel ICA study to investigate differential linkage between neural networks and genetic profiles in schizophrenia.	DCDC2 COMT DISC1	4.02e-05	15	158	3	19944766
Pubmed	Voltage-dependent conformational changes of Kv1.3 channels activate cell proliferation.	AFF2 LRRK2 RNF213 ORC1 KMT2A TRPM1 PLS3	4.92e-05	208	158	7	33230847
Pubmed	Cytoplasmic Metadherin (MTDH) provides survival advantage under conditions of stress by acting as RNA-binding protein.	DOCK2 SYNE1 RNF213 ADGRA2 ITPR3 NEO1 DOP1B	5.88e-05	214	158	7	22199357
Pubmed	Antagonistic regulation of type I collagen gene expression by interferon-gamma and transforming growth factor-beta. Integration at the level of p300/CBP transcriptional coactivators.	STAT1 SMAD3	6.13e-05	3	158	2	11134049
Pubmed	Successful in vitro fertilization and generation of transgenics in Black and Tan Brachyury (BTBR) mice.	DISC1 ITPR3	6.13e-05	3	158	2	27515175
Pubmed	Expression of the mouse Macf2 gene during inner ear development.	DST MACF1	6.13e-05	3	158	2	12399109
Pubmed	Mutations in origin recognition complex gene ORC4 cause Meier-Gorlin syndrome.	ORC1 CDT1	6.13e-05	3	158	2	21358631
Pubmed	CCL21 mediates CD4+ T-cell costimulation via a DOCK2/Rac-dependent pathway.	DOCK2 PIK3CD	6.13e-05	3	158	2	19451552
Pubmed	Association of functional polymorphisms in 3'-untranslated regions of COMT, DISC1, and DTNBP1 with schizophrenia: a meta-analysis.	COMT DISC1	6.13e-05	3	158	2	30252773
Pubmed	RBX1 (RING box protein 1) E3 ubiquitin ligase is required for genomic integrity by modulating DNA replication licensing proteins.	ORC1 CDT1	6.13e-05	3	158	2	21115485
Pubmed	Phagocytosis-dependent activation of a TLR9-BTK-calcineurin-NFAT pathway co-ordinates innate immunity to Aspergillus fumigatus.	TLR9 BTK	6.13e-05	3	158	2	25637383
Pubmed	A transgenic insertion causing cryptorchidism in mice.	FRY RXFP2	6.13e-05	3	158	2	11353515
Pubmed	The inner nuclear membrane protein Sun1 mediates the anchorage of Nesprin-2 to the nuclear envelope.	SYNE1 SYNE2	6.13e-05	3	158	2	16079285
Pubmed	Mapping of the X-linked immune deficiency mutation (xid) of CBA/N mice.	PHEX BTK	6.13e-05	3	158	2	7365241
Pubmed	Sestrin 3 protein enhances hepatic insulin sensitivity by direct activation of the mTORC2-Akt signaling.	SESN3 SESN2	6.13e-05	3	158	2	25377878
Pubmed	Bruton's tyrosine kinase regulates TLR9 but not TLR7 signaling in human plasmacytoid dendritic cells.	TLR9 BTK	6.13e-05	3	158	2	24375473
Pubmed	Signaling by Toll-like receptors 8 and 9 requires Bruton's tyrosine kinase.	TLR9 BTK	6.13e-05	3	158	2	17932028
Pubmed	Integrin alpha6beta4 promotes expression of autotaxin/ENPP2 autocrine motility factor in breast carcinoma cells.	ENPP2 ITGA6	6.13e-05	3	158	2	15897878
Pubmed	The Parkinson's Disease Protein LRRK2 Interacts with the GARP Complex to Promote Retrograde Transport to the trans-Golgi Network.	LRRC32 LRRK2	6.13e-05	3	158	2	32375042
Pubmed	Role of phosphoinositide 3-kinase p110 delta in TLR4- and TLR9-mediated B cell cytokine production and differentiation.	TLR9 PIK3CD	6.13e-05	3	158	2	19362372
Pubmed	FLT3-ITD and TLR9 use Bruton tyrosine kinase to activate distinct transcriptional programs mediating AML cell survival and proliferation.	TLR9 BTK	6.13e-05	3	158	2	25605370
Pubmed	SESN1, negatively regulated by miR-377-3p, suppresses invasive growth of head and neck squamous cell carcinoma by interaction with SMAD3.	SESN1 SMAD3	6.13e-05	3	158	2	35622213
Pubmed	Syne-1, a dystrophin- and Klarsicht-related protein associated with synaptic nuclei at the neuromuscular junction.	SYNE1 SYNE2	6.13e-05	3	158	2	10878022
Pubmed	STAT1-independent down-regulation of interferon-gamma-induced class II transactivator and HLA-DR expression by transforming growth factor beta-1 in human glomerular endothelial cells.	STAT1 SMAD3	6.13e-05	3	158	2	15824515
Pubmed	Impact of COMT, PRODH and DISC1 Genetic Variants on Cognitive Performance of Patients with Schizophrenia.	COMT DISC1	6.13e-05	3	158	2	35367090
Pubmed	Macrophage neogenin deficiency exacerbates myocardial remodeling and inflammation after acute myocardial infarction through JAK1-STAT1 signaling.	STAT1 NEO1	6.13e-05	3	158	2	37824022
Pubmed	The nesprins are giant actin-binding proteins, orthologous to Drosophila melanogaster muscle protein MSP-300.	SYNE1 SYNE2	6.13e-05	3	158	2	12408964
Pubmed	Elevated FBXL18 promotes RPS15A ubiquitination and SMAD3 activation to drive HCC.	FBXL18 SMAD3	6.13e-05	3	158	2	37378633
Pubmed	Meier-Gorlin syndrome genotype-phenotype studies: 35 individuals with pre-replication complex gene mutations and 10 without molecular diagnosis.	ORC1 CDT1	6.13e-05	3	158	2	22333897
Pubmed	Polymorphisms of plasminogen activator inhibitor-1, angiotensin converting enzyme and coagulation factor XIII genes in patients with recurrent spontaneous abortion.	ACE F13A1	6.13e-05	3	158	2	20822334
Pubmed	Distinct functional domains in nesprin-1alpha and nesprin-2beta bind directly to emerin and both interactions are disrupted in X-linked Emery-Dreifuss muscular dystrophy.	SYNE1 SYNE2	6.13e-05	3	158	2	17462627
Pubmed	Combinations of fibrinolytic gene polymorphisms (plasminogen activator inhibitor type 1 4G/5G, factor XIII Val34Leu and angiotensin-converting enzyme I/D) in women with idiopathic infertility.	ACE F13A1	6.13e-05	3	158	2	33555692
Pubmed	Tumor suppressive role of sestrin2 during colitis and colon carcinogenesis.	SESN3 SESN2	6.13e-05	3	158	2	26913956
Pubmed	Genetic variations in a Sestrin2/Sestrin3/mTOR Axis and development of new-onset diabetes after kidney transplantation.	SESN3 SESN2	6.13e-05	3	158	2	37918578
Interaction	YWHAH interactions	GBF1 TEX2 SPEG LRRK2 PRPF6 WDR26 DENND1A SYNGAP1 USP31 TBC1D10B DST SYNJ2 TESK2 SHCBP1 SYNE2 KMT2A MACF1 AKAP13 RASSF8 MAP4K4 TRAPPC9 SEC23B CRTC2 DOP1B	3.33e-06	1102	154	24	int:YWHAH
GeneFamily	Spectrin repeat containing nuclear envelope family	SYNE1 SYNE2	1.99e-04	4	105	2	1252
GeneFamily	Neuroblastoma breakpoint family	NBPF4 NBPF6 NBPF5P	3.10e-04	23	105	3	662
GeneFamily	Blood group antigens\|CD molecules\|I-set domain containing\|Immunoglobulin like domain containing	SPEG MYOM3 IGFBPL1 NEO1 PXDN LINGO4	3.54e-04	161	105	6	593
GeneFamily	EF-hand domain containing\|Plakins	DST MACF1	9.14e-04	8	105	2	939
GeneFamily	EF-hand domain containing	CRACR2A CETN3 SPTA1 DST MACF1 PLS3	1.75e-03	219	105	6	863
GeneFamily	Tubulin tyrosine ligase family	TTLL6 TTLL13	2.90e-03	14	105	2	779
GeneFamily	AAA ATPases	ORC1 MDN1 ATAD2B	3.61e-03	53	105	3	413
Coexpression	HU_FETAL_RETINA_RPE	DCDC2 TEX2 ENPP2 SESN3 ITGA6 PXDN ACOT11 TRPM1 RASSF8 PLS3 SMAD3	1.37e-06	291	155	11	M39271
Coexpression	GSE38696_LIGHT_ZONE_VS_DARK_ZONE_BCELL_UP	TPCN2 SYNE1 SESN3 ALS2CL STAT1 PSME4 MACF1 MAP4K4 CEP97	1.59e-06	184	155	9	M9005
Coexpression	GSE14350_IL2RB_KO_VS_WT_TREG_UP	ALS2CL STAT1 ITPR3 FOCAD ARSB MDN1 SYNJ2 GALNT6 PDE11A	3.02e-06	199	155	9	M3421
Coexpression	NAKAYA_PLASMACYTOID_DENDRITIC_CELL_FLUMIST_AGE_18_50YO_7DY_UP	VPS11 RETREG2 COMT KIF1A EML4 CETN3 ENPP2 PRPF6 OCRL SESN1 MDN1 ST3GAL6 TCL1A ATAD2B BTK SYNE2 PAXIP1 KMT2A MACF1 SEC23B SMAD3	1.03e-05	1215	155	21	M41122
Coexpression	LAKE_ADULT_KIDNEY_C29_UNKNOWN_NOVEL_PT_CFH_POS_SUBPOPULATION_S2	DCDC2 SYNE1 DST FER MACF1 TRAPPC9	1.24e-05	86	155	6	M39248
Coexpression	LAKE_ADULT_KIDNEY_C6_PROXIMAL_TUBULE_EPITHELIAL_CELLS_FIBRINOGEN_POS_S3	CAB39 MACC1 LRRK2 RNF213 STAT1 SYNE2 MACF1 ALDH6A1	1.28e-05	181	155	8	M39225
Coexpression	GSE11057_EFF_MEM_VS_CENT_MEM_CD4_TCELL_DN	USP34 SESN3 SFI1 ALS2CL MDN1 KMT2A MACF1 MAP4K4	1.76e-05	189	155	8	M3112
Coexpression	GSE30083_SP1_VS_SP4_THYMOCYTE_DN	ITGA6 RNF213 ALS2CL SESN1 ARSB DNAJA4 SYNE2 KMT2A	2.64e-05	200	155	8	M5030
Coexpression	GSE15330_LYMPHOID_MULTIPOTENT_VS_MEGAKARYOCYTE_ERYTHROID_PROGENITOR_IKAROS_KO_UP	GRAMD1A SESN3 ALS2CL SESN1 MDN1 LRP6 CEP97	6.10e-05	166	155	7	M7009
Coexpression	GSE15330_HSC_VS_MEGAKARYOCYTE_ERYTHROID_PROGENITOR_DN	SESN3 ALS2CL SESN1 MDN1 ABRAXAS1 LRP6 CEP97	6.58e-05	168	155	7	M7007
Coexpression	GSE3565_CTRL_VS_LPS_INJECTED_DUSP1_KO_SPLENOCYTES_DN	GRAMD1A ALS2CL WDR26 SESN1 MDN1 AKAP13 MAP4K4	7.36e-05	171	155	7	M6321
Coexpression	GSE14415_ACT_TCONV_VS_ACT_NATURAL_TREG_UP	ITGA6 RNF213 ALS2CL SESN1 STAT1 MAP4K4 CEP97	7.63e-05	172	155	7	M2945
CoexpressionAtlas	CD positive, CD4 Control, 4+ 8- B220-, Spleen, avg-4	GRAMD1A LRRC32 SESN3 ITGA6 ALS2CL MDN1 KMT2A MACF1 GALNT6 CEP97	3.22e-06	210	154	10	GSM403995_500
CoexpressionAtlas	FacebaseRNAseq_e10.5_Maxillary Arch_top-relative-expression-ranked_1000_k-means-cluster#3	AFF2 SYNE1 DYNC2I1 RNF213 PRPF6 STEAP2 F13A1 FUT11 ACOT11 ABRAXAS1 ATAD2B MACF1 TRPM1	1.67e-05	432	154	13	Facebase_RNAseq_e10.5_Maxillary Arch_1000_K3
CoexpressionAtlas	FacebaseRNAseq_e10.5_Maxillary Arch_top-relative-expression-ranked_1000	DCDC2 KRT13 AFF2 SYNE1 DYNC2I1 RNF213 PRPF6 SFI1 STEAP2 RFX4 IGFBPL1 F13A1 FUT11 ZSCAN10 ACOT11 ABRAXAS1 ATAD2B SYNE2 MACF1 TRPM1	3.26e-05	989	154	20	Facebase_RNAseq_e10.5_Maxillary Arch_1000
CoexpressionAtlas	CD positive, CD4 Test DB, 4+8-B220-, Spleen, avg-1	GRAMD1A LRRC32 SESN3 ITGA6 ALS2CL STAT1 MDN1 MACF1 GALNT6 CEP97 PDE11A	3.75e-05	338	154	11	GSM403987_500
CoexpressionAtlas	CD positive, CD4 Control, 4+8-B220-, Spleen, avg-2	GRAMD1A LRRC32 SESN3 ITGA6 ALS2CL MDN1 MACF1 GALNT6 CEP97	3.88e-05	224	154	9	GSM403994_500
CoexpressionAtlas	CD positive, CD4 Test NA, 4+8-B220-, Spleen, avg-1	GRAMD1A LRRC32 SESN3 ITGA6 ALS2CL SESN1 FOCAD GALNT6 CEP97 ZNF287 PDE11A	6.14e-05	357	154	11	GSM403986_500
CoexpressionAtlas	FacebaseRNAseq_e10.5_Maxillary Arch_top-relative-expression-ranked_500	KRT13 AFF2 SYNE1 DYNC2I1 RNF213 SFI1 RFX4 IGFBPL1 F13A1 ZSCAN10 ACOT11 ATAD2B TRPM1	6.37e-05	492	154	13	Facebase_RNAseq_e10.5_Maxillary Arch_500
CoexpressionAtlas	BM Top 100 - medulla	GPR37 RFX4 SYNJ2 UGT8 MAP4K4	1.02e-04	64	154	5	BM Top 100 - medulla
CoexpressionAtlas	FacebaseRNAseq_e10.5_Medial Nasal Eminence_top-relative-expression-ranked_2500_k-means-cluster#4	LRRC39 SYNE1 LRRK2 DYNC2I1 RNF213 ALS2CL ADGRA2 F13A1 ACOT11 TESK2 ATAD2B MDC1 MACF1 AKAP13 TRPM1 ZNF287	1.05e-04	744	154	16	Facebase_RNAseq_e10.5_Medial Nasal Eminence_2500_K4
CoexpressionAtlas	BM Top 100 - spinal cord	GPR37 RFX4 SYNJ2 UGT8 MAP4K4	1.09e-04	65	154	5	BM Top 100 - spinal cord
CoexpressionAtlas	BM Top 100 - nodose nucleus	GPR37 ENPP2 SYNJ2 UGT8 MAP4K4	1.18e-04	66	154	5	BM Top 100 - nodose nucleus
CoexpressionAtlas	BM Top 100 - corpus callosum	GPR37 ENPP2 SYNJ2 UGT8 MAP4K4	1.18e-04	66	154	5	BM Top 100 - corpus callosum
CoexpressionAtlas	alpha beta T cells, T.4Nve.PP, TCR+ CD4+ CD44low CD62Lhigh, Peyer's Patch, avg-2	GRAMD1A SESN3 ITGA6 ALS2CL MDN1 MACF1 GALNT6 CEP97 ZNF287 PDE11A	1.42e-04	327	154	10	GSM538380_500
CoexpressionAtlas	alpha beta T cells, T.4Nve.LN, 4+ 8- 25- 62Lhi 44lo, Lymph Node, avg-3	GRAMD1A SESN3 ITGA6 ALS2CL STAT1 FOCAD GALNT6 CEP97 ZNF287 PDE11A	1.77e-04	336	154	10	GSM538374_500
CoexpressionAtlas	alpha beta T cells, T.8Nve.PP, TCRb+ CD8+ CD44low CD62L high, Peyer's Patch, avg-1	CRACR2A GRAMD1A SESN3 ITGA6 ALS2CL MDN1 KMT2A MACF1 GALNT6 CEP97	1.77e-04	336	154	10	GSM538413_500
CoexpressionAtlas	Mesoderm Day 15_vs_Mesoderm Day 5-Confounder_removed-fold2.0_adjp0.05	HDHD3 GBF1 TEX2 ENPP2 SESN3 TMEM214 SFI1 ADGRA2 DENND1A SESN1 ST3GAL6 ACOT11 TESK2 GGTLC1 ETNK2 SESN2 ALDH6A1 DGAT1 SMAD3	2.19e-04	1049	154	19	PCBC_ratio_MESO-15_vs_MESO-5_cfr-2X-p05
CoexpressionAtlas	alpha beta T cells, T.4Mem.LN, TCRb CD44high CD122lo CD4, Lymph Node, avg-3	GRAMD1A LRRC32 SESN3 ITGA6 ALS2CL STAT1 SYNJ2 GALNT6 CEP97 PDE11A	2.34e-04	348	154	10	GSM538362_500
CoexpressionAtlas	alpha beta T cells, T.4SP24-.Th, 4+ 8- TCRhi 24-/lo, Thymus, avg-3	GRAMD1A LRRC32 SESN3 ITGA6 RNF213 ALS2CL STAT1 FOCAD GALNT6 CEP97	3.42e-04	365	154	10	GSM399370_500
ToppCell	mild-MAIT\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	EML4 SYNE1 ITGA6 RNF213 SESN1 NEO1 GTF3C1 SYNE2 MACF1	4.11e-08	199	158	9	cbe1fb6d2c5fca7a1baf1ad20afcdf8e8e11bd84
ToppCell	LPS_IL1RA-Endothelial-Endothelial-Gen_Cap\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	USP34 ENPP2 ITGA6 RNF213 ACE DST SYNE2 KMT2A MACF1	4.29e-08	200	158	9	dccec522ab0d7fff62ad6273b02aa9022dbbb8eb
ToppCell	3'_v3-lymph-node_spleen-Lymphocytic_T_CD4-T_CD4/CD8\|lymph-node_spleen / Manually curated celltypes from each tissue	EML4 HIPK1 SYNE1 SESN3 RNF213 SFI1 SYNE2 MACF1	1.83e-07	171	158	8	2e9a20f8980b78325c52065a9c14ab3656267c05
ToppCell	severe-low-quality_cells\|severe / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	EML4 SYNE1 SESN3 RNF213 SFI1 ATAD2B SYNE2 MACF1	4.61e-07	193	158	8	9337bc93e3904c7fc7c93c328518bcd6453b1e8c
ToppCell	severe-low-quality_cells\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	USP34 EML4 SYNE1 SESN3 RNF213 SYNE2 KMT2A MACF1	5.38e-07	197	158	8	57ebd552f10d6278623b52a3d484d4b91ae1d028
ToppCell	3'_v3-blood-Lymphocytic_T_CD4-T_CD4/CD8\|blood / Manually curated celltypes from each tissue	EML4 SYNE1 RNF213 SFI1 SYNE2 MACF1 AKAP13	5.48e-07	135	158	7	ae2d3a42e567b5bade304c0caa497eb725be3565
ToppCell	mild-low-quality_cells\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	USP34 EML4 SYNE1 RNF213 SFI1 ATAD2B SYNE2 MACF1	5.81e-07	199	158	8	f0b0097df0026496470a80d8cc9375ffd8389b00
ToppCell	Brain_organoid-organoid_Tanaka_cellReport-6m-Mesenchymal-BMP_responsible_cell\|6m / Sample Type, Dataset, Time_group, and Cell type.	DCDC2 ENPP2 ZBBX FOCAD ACOT11 SYNE2 TRPM1 PDE11A	6.03e-07	200	158	8	5fb90118d3abc28d72bc483e68317255090a04c7
ToppCell	mild\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	USP34 RNF213 STAT1 ATAD2B SYNE2 KMT2A MACF1 AKAP13	6.03e-07	200	158	8	12f1685ce8f218433068e090c9d839cd5a1910bf
ToppCell	COVID-19-COVID-19_Mild-Lymphocyte-T/NK-CD4+_T_activated\|COVID-19_Mild / Disease, condition lineage and cell class	SESN3 ITGA6 RNF213 ALS2CL STAT1 DST MDN1 SYNE2	6.03e-07	200	158	8	d9e8a0d047d4403fb7265fde7448e23a7780785c
ToppCell	droplet-Heart-HEART_(ALL_4:4:4:1:1)-30m-Hematologic-leukocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DOCK2 TLR9 F13A1 ORC1 ARL10 SESN2 GALNT6	1.22e-06	152	158	7	bfc7ef4ee26165d18ac4f475a9519e8d52453ba2
ToppCell	COVID-19_Moderate-multiplets\|World / disease group, cell group and cell class	EML4 SYNE1 RNF213 SFI1 ITPR3 SYNE2 MACF1	1.45e-06	156	158	7	afdc025fa75e7926b1cc182c4a33654a2186abb1
ToppCell	10x5'-blood-Lymphocytic_T_CD4-T_CD4/CD8\|blood / Manually curated celltypes from each tissue	USP34 EML4 SPEG SESN3 SFI1 SYNE2 MACF1	1.86e-06	162	158	7	b4535bcb3f469bc139e73f1122f4070013e5a1de
ToppCell	356C-Myeloid-Macrophage-FABP4+_Macrophage\|Myeloid / Donor, Lineage, Cell class and subclass (all cells)	SYNE1 DYNC2I1 NEO1 ZSCAN30 LRP6 C6orf141 PLS3	2.19e-06	166	158	7	89e2b8453180983533faccb4275867861876d7ee
ToppCell	368C-Lymphocytic-CD4_T-cell-Treg_cell_1\|CD4_T-cell / Donor, Lineage, Cell class and subclass (all cells)	DOCK2 TEX2 DISC1 WDR26 GTF3C4 F13A1 ITPR3	2.88e-06	173	158	7	efb8072475000888efe088d00e870c56ffad4172
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Immune-Myeloid-Macrophage_Dendritic-Plasmacytoid_Dendritic_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	DOCK2 DISC1 PHEX PIK3CD TCL1A BTK ZFYVE26	3.23e-06	176	158	7	8488997e0f02e874f53fae1690da63e0dd1d0780
ToppCell	Adult-Immune-interstitial_macrophage_(C1Q_positive)-D175\|Adult / Lineage, Cell type, age group and donor	DOCK2 CAB39 ENPP2 DISC1 DENND1A F13A1 ARSB	4.48e-06	185	158	7	ab5704b96f1d368911308797d10c7c52766ab134
ToppCell	10x5'-GI_small-bowel-Lymphocytic_T_CD4-T_CD4/CD8\|GI_small-bowel / Manually curated celltypes from each tissue	USP34 EML4 HIPK1 RNF213 SYNE2 KMT2A MACF1	4.98e-06	188	158	7	ab9b725d6e0cdab8e9ddda6dee09e14730e9a578
ToppCell	10x5'-lymph-node_spleen-Lymphocytic_T_CD4-T_CD4/CD8\|lymph-node_spleen / Manually curated celltypes from each tissue	EML4 HIPK1 RNF213 SFI1 SYNE2 KMT2A MACF1	5.72e-06	192	158	7	47646d7e4990be85072987f92bf18d52f8da752e
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive\|renal_cortex_nuclei / Celltypes from Cells and Nuclei per compartment and clinical group	CAB39 EML4 SYNJ2 MACF1 AKAP13 MAP4K4 SMAD3	5.72e-06	192	158	7	8b86db2ebe0199fee0e9800566a619a24bfdeed5
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Intermediate_tubule_epithelial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	MACC1 DCDC2 SYNE1 LRRK2 RNF213 ITPR3 SYNE2	6.12e-06	194	158	7	e577d9e88390b36b5a09b97fe1026089892275a3
ToppCell	COVID_non-vent-Lymphocytic-T_cell-CD4+_Memory_T_cell\|COVID_non-vent / Disease condition, Lineage, Cell class and subclass	EML4 SESN3 ITGA6 ALS2CL DST SYNE2 KMT2A	6.33e-06	195	158	7	22191d361af136942508f1553ff41a626ed982ad
ToppCell	10x_3'_v2v3-Non-neoplastic-Glial-Neuronal-Oligodendrocyte-Oligodendrocyte-B\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	KIF1A GPR37 ENPP2 USP31 DST SYNJ2 UGT8	6.77e-06	197	158	7	82b8e22317cad6d3786bd70d91107007c0ccd7cd
ToppCell	Bronchial-10x5prime-Epithelial-Epi_alveolar-Dividing_AT2\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	ORC1 GGTLC1 SHCBP1 PAXIP1 UGT8 CDT1 C6orf141	6.77e-06	197	158	7	49689a03ab31e53386dbe15c77c09ca3a14ebf4e
ToppCell	Control_saline-Endothelial-Endothelial-Gen_Cap\|Control_saline / Treatment groups by lineage, cell group, cell type	ENPP2 LRRC32 ITGA6 ACE DST MACF1 MAP4K4	7.47e-06	200	158	7	3b97920e1e6e2f09ddba2a861baa9c00c2970f4c
ToppCell	Bronchial-NucSeq-Epithelial-Epi_submucosal-gland\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	CRACR2A ITGA6 SYNJ2 ACOT11 UGT8 GALNT6 DOP1B	7.47e-06	200	158	7	85c0f038bcfb42669dca2b80273b0f8a1421405e
ToppCell	TCGA-Bone_and_Soft_Tissue-Primary_Tumor-Sarcoma-Monophasic_Synovial_Sarcoma\|TCGA-Bone_and_Soft_Tissue / Sample_Type by Project: Shred V9	HES2 ZBBX EIF4E1B COL23A1 ZSCAN10 SLC27A5	9.59e-06	137	158	6	576ca865b8e8e59d23aa35cb9dafee0cf7d38e6a
ToppCell	frontal_cortex-Neuronal-glutamatergic_neuron-L2/3_IT-L2/3_IT_ALM_Macc1_Lrg1\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	MACC1 ENPP2 DISC1 LRRC32 ETNK2 SMAD3	1.18e-05	142	158	6	d08e1880425d285c4433014fe0242ac7ff7734af
ToppCell	droplet-Heart-HEART_(ALL_4:4:4:1:1)-30m-Hematologic\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DOCK2 TLR9 F13A1 ORC1 ARL10 GALNT6	1.18e-05	142	158	6	39ada235a46f2202c093cf2336de224a5957ed1a
ToppCell	droplet-Heart-HEART_(ALL_4:4:4:1:1)-30m-Hematologic-leukocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DOCK2 TLR9 F13A1 ARL10 SESN2 GALNT6	1.49e-05	148	158	6	7c7c87b57aa16f8b91698489df39ace5a3a53df8
ToppCell	10x5'-bone_marrow-Lymphocytic_T_CD4-T_CD4/CD8\|bone_marrow / Manually curated celltypes from each tissue	EML4 HIPK1 RNF213 PSME4 SYNE2 MACF1	2.01e-05	156	158	6	1545169694f686d28648a68b552c2ae606599d66
ToppCell	wk_08-11-Mesenchymal-Myofibro_&_SMC-Myofibro_2\|wk_08-11 / Celltypes from embryonic and fetal-stage human lung	IPO4 ZBBX COL23A1 MTMR11 DNAH9 SMAD3	3.25e-05	170	158	6	fefb07a7e308b620f946b9ff2b01e1796446fe38
ToppCell	368C-Lymphocytic-CD4_T-cell-Treg_cell_1\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	TEX2 DISC1 WDR26 GTF3C4 F13A1 FOCAD	3.71e-05	174	158	6	58300d64d3b6fd9ba1b6c87ea83b2777eb6be2f4
ToppCell	droplet-Marrow-nan-3m-Lymphocytic-NK_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	AFF2 SYNE1 LRRK2 ACE TESK2 SYNE2	3.83e-05	175	158	6	cf53a15bfb37b6019e7052ffdf594a9ac040900e
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Neuronal-Glutamatergic_Excit-Glut_E_(THEMIS)-Glut_D_(IT_RORB_THEMIS_LINC00507)_6-Exc_L5-6_THEMIS_TMEM233\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	COL23A1 PXDN SYNJ2 RXFP2 AKAP13 SMAD3	4.34e-05	179	158	6	747a32460b257fffca30527b56a74720eb9c12e4
ToppCell	5'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.3.0\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	DYNC2I1 ZBBX SYNGAP1 ZSCAN5B TTLL6 DNAH9	4.34e-05	179	158	6	5e5f1cdf4aa66868d45b74ba91e20e848a3cbaff
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	MACC1 MYO7B LRRK2 MYOM3 COL23A1 SMAD3	4.34e-05	179	158	6	58ae5a97fe2a14e1c6fdeb886397eb06fdaf0428
ToppCell	10x5'-Liver-Lymphocytic_T_CD4-T_CD4/CD8\|Liver / Manually curated celltypes from each tissue	USP34 EML4 RNF213 SFI1 SYNE2 MACF1	4.62e-05	181	158	6	f2315414e714ac86211546a935660c4be6e85f1b
ToppCell	P28-Epithelial-airway_epithelial_cell-club_cell\|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	DCDC2 ZBBX TTLL6 UGT8 KIAA2012 DNAH9	5.37e-05	186	158	6	a26811481668fa25c48a064a56c198685693ad8d
ToppCell	control-Myeloid-pDC\|control / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs	TEX2 ENPP2 PHEX TCL1A RASSF8 PLS3	5.37e-05	186	158	6	fe31e9cf4575ee40b50489593c51d8c36c3cc532
ToppCell	healthy_donor-Lymphocytic-Dendritic\|healthy_donor / Disease condition, Lineage, Cell class and subclass	TEX2 ENPP2 TLR9 PHEX RASSF8 PLS3	5.37e-05	186	158	6	916f2aeea4989ba7a29e071e348a51010f010223
ToppCell	P28-Epithelial-airway_epithelial_cell\|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	DCDC2 ZBBX TTLL6 UGT8 KIAA2012 DNAH9	5.37e-05	186	158	6	df80f101954b8ec6ccdb03e702de22e70b65181f
ToppCell	healthy_donor-Lymphocytic-Dendritic-pDC\|healthy_donor / Disease condition, Lineage, Cell class and subclass	TEX2 ENPP2 TLR9 PHEX RASSF8 PLS3	5.37e-05	186	158	6	45f66619e45d590c7365a51782d4ac46b7d31fde
ToppCell	facs-Lung-EPCAM-3m-Epithelial-Ciliated_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CCDC60 DCDC2 ZBBX TTLL6 KIAA2012 DNAH9	5.53e-05	187	158	6	04dba2ed09ee4180830bdf0191921696697ea234
ToppCell	facs-Lung-EPCAM-3m-Epithelial-ciliated_columnar_cell_of_tracheobronchial_tree\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CCDC60 DCDC2 ZBBX TTLL6 KIAA2012 DNAH9	5.53e-05	187	158	6	805dafe22f835ece4dd091d8030d0a63b52a48dd
ToppCell	tumor_Lymph_Node_/_Brain-Fibroblasts-Undetermined\|tumor_Lymph_Node_/_Brain / Location, Cell class and cell subclass	TEX2 ZSCAN5A LRRC32 ARL10 SYNJ2 ETNK2	5.70e-05	188	158	6	8231e635706a296db6b6da1029a33bbc1b52478e
ToppCell	-Unknown-Endothelial-Myofibroblast\| / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	LRRK2 ATAD2B PAXIP1 KMT2A RASSF8 SMAD3	5.70e-05	188	158	6	6468fa95ad0395395301115286f2d8c0df5d3882
ToppCell	-Unknown-Endothelial\| / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	LRRK2 ATAD2B PAXIP1 KMT2A RASSF8 SMAD3	5.70e-05	188	158	6	7a81ac5c79c3eb26639b52d2b9fd5e7ef9798fd6
ToppCell	-Unknown\| / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	LRRK2 ATAD2B PAXIP1 KMT2A RASSF8 SMAD3	5.70e-05	188	158	6	9cb718bfe1358c6fd842f096e228eb0abb9aefc6
ToppCell	Epithelial-Epithelial-D_(Ciliated)\|Epithelial / shred on cell class and cell subclass (v4)	SYNE1 DYNC2I1 ZBBX TTLL6 KIAA2012 DNAH9	5.70e-05	188	158	6	8f30535a32968a81a304315a49c0d90a77d36948
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	MACC1 DCDC2 LRRK2 RNF213 ITPR3 DST	5.87e-05	189	158	6	aadb7a2de4cbe7f0958651f2739bba430b93f5c1
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	MACC1 DCDC2 AFF2 MYO7B MYOM3 SYNE2	5.87e-05	189	158	6	28b502611829e4a24caff2562545c7db97686099
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Thick_Ascending_Limb_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	MACC1 DCDC2 LRRK2 RNF213 ITPR3 DST	5.87e-05	189	158	6	8977f3295b7df7c7474b3f371de90a82ae4bb50c
ToppCell	COVID-19-kidney-PCT-S2\|kidney / Disease (COVID-19 only), tissue and cell type	MACC1 AFF2 MYO7B MYOM3 COL23A1 SYNE2	5.87e-05	189	158	6	0be5c669b6b308bd98ddb70c84877c62a6244bbd
ToppCell	BALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c03-ITGA4\|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)	GRAMD1A SESN3 ACE SYNE2 MACF1 SMAD3	6.04e-05	190	158	6	91ba66d4b56c59523485b17738e93f14bb00afa4
ToppCell	facs-Lung-nan-3m-Epithelial-Ciliated_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CCDC60 DCDC2 RFX4 ZBBX KIAA2012 DNAH9	6.04e-05	190	158	6	e243b5fbb17b9ec3cc90bbe970c1d30b0fd1c2e1
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	MACC1 DCDC2 SYNE1 LRRK2 ITPR3 UGT8	6.04e-05	190	158	6	3fc9e18c7441c0ae8cda65753cc42d0520f4e116
ToppCell	Mesenchymal_cells-Smooth_muscle\|World / Lineage and Cell class	SPEG LRRC32 MYOM3 ETNK2 AOC3 PLS3	6.04e-05	190	158	6	5aa62a363a25f4a110136263b21289a11e8c1e6d
ToppCell	facs-Lung-nan-3m-Epithelial-ciliated_columnar_cell_of_tracheobronchial_tree\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CCDC60 DCDC2 RFX4 ZBBX KIAA2012 DNAH9	6.04e-05	190	158	6	fe844559b95832845d2e8d3ab4b57e3d558bc372
ToppCell	PND03-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Ciliated\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	DCDC2 DYNC2I1 ZBBX TTLL6 KIAA2012 DNAH9	6.22e-05	191	158	6	bda8faf92495c8b362850c0aff4fc6fbdd9c563b
ToppCell	PND03-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Ciliated-Ciliated_mature\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	DCDC2 DYNC2I1 ZBBX TTLL6 KIAA2012 DNAH9	6.22e-05	191	158	6	6880fb348bb0915db9a5da4f3566ca9ff93ed258
ToppCell	facs-Pancreas-Endocrine-3m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GBF1 KIF1A ENPP2 DST ACOT11 PAXIP1	6.40e-05	192	158	6	5b7093d5af5ae7b0e6d3a464cc56272440ecedad
ToppCell	PND03-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	DCDC2 DYNC2I1 ZBBX TTLL6 KIAA2012 DNAH9	6.40e-05	192	158	6	b5cdc2dae3154b1e4ade88f841f38584402ffe33
ToppCell	systemic_lupus_erythematosus-flare-Lymphocytic_T-CytoT_GZMK+\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	EML4 SYNE1 RNF213 SYNE2 MACF1 CDT1	6.40e-05	192	158	6	6779b0294bb058e748e22b795b6a381c4add37e9
ToppCell	PND03-Epithelial-Epithelial_Airway\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	DCDC2 DYNC2I1 ZBBX TTLL6 KIAA2012 DNAH9	6.40e-05	192	158	6	2d8d5a38e205339eda9c8aca1ca9ba3dcbe5ae56
ToppCell	nucseq\|World / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	USP34 DENND1A ARL10 AKAP13 COG5 TRAPPC9	6.59e-05	193	158	6	779276e775cb2492e8dd36436295a536084a6415
ToppCell	10x_3'_v2v3-Non-neoplastic-Glial-Neuronal-Oligodendrocyte-Oligodendrocyte-D\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	KIF1A GPR37 ENPP2 DST SYNJ2 UGT8	6.59e-05	193	158	6	947200ef6c3a2e35ad7e6b4af29d92384bdf73f5
ToppCell	10x5'-GI_small-bowel-Lymphocytic_T_CD4\|GI_small-bowel / Manually curated celltypes from each tissue	EML4 RNF213 STAT1 NEO1 SYNE2 MAP4K4	6.78e-05	194	158	6	4547b57669be5d4f0de55175802ee04372288a6a
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	MACC1 DCDC2 RNF213 ITPR3 DST SMAD3	6.98e-05	195	158	6	938b31dbf1674ee6fd0123bc88391ddcaf151217
ToppCell	facs-Pancreas-Endocrine-18m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GBF1 KIF1A ENPP2 DST ACOT11 PAXIP1	6.98e-05	195	158	6	bd8e24dd598990204998d1dd853ba7a53dc0107e
ToppCell	COVID-19-Heart-CM_2\|Heart / Disease (COVID-19 only), tissue and cell type	MYOM3 FRY DST ST3GAL6 ACOT11 AKAP13	6.98e-05	195	158	6	75fc81bddb246dca3b437fb60827b1d4fe416405
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Thick_Ascending_Limb_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	MACC1 DCDC2 RNF213 ITPR3 DST SMAD3	6.98e-05	195	158	6	d39e9e6544f49e677ebe528c6fe60b99a3630e30
ToppCell	ILEUM-inflamed-(6)_ILC3\|inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)	EML4 PRPF6 NEO1 DST LINGO4 RASSF8	6.98e-05	195	158	6	c6968da7d2b60c2163e1ff0ffa41340e1ec1d2ed
ToppCell	PBMC_fresh-frozen-Mild-Moderate_progression_d12-25-Lymphocytic\|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)	USP34 EML4 HIPK1 SESN3 SYNE2 KMT2A	6.98e-05	195	158	6	ed5f772c82d4dfd1c8735224446ec9feae3fb8c2
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Glial-Neuronal-Oligodendrocyte-Oligodendrocyte-E\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	KIF1A GPR37 ENPP2 USP31 DST UGT8	7.18e-05	196	158	6	37a5f9f3988778655580bd0383811bb4930c1551
ToppCell	3'_v3-bone_marrow-Lymphocytic_T_CD4-T_CD4/CD8\|bone_marrow / Manually curated celltypes from each tissue	EML4 SYNE1 RNF213 SYNE2 MACF1	7.18e-05	121	158	5	19333a660800b583fa27b495c1f7828e6636a257
ToppCell	5'-Airway_Nasal-Epithelial-Airway_ciliated\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	SYNE1 DYNC2I1 ZBBX DNAJA4 KIAA2012 DNAH9	7.38e-05	197	158	6	91637bdeab85024b5a02d1066f76cb803a2d6420
ToppCell	5'-Airway_Nasal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	SYNE1 DYNC2I1 ZBBX DNAJA4 KIAA2012 DNAH9	7.38e-05	197	158	6	22c87dd15dc57bd0aa98a204c9fc9b3b9b573b45
ToppCell	3'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.2\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	SYNE1 DYNC2I1 ZBBX TTLL6 SYNE2 DNAH9	7.38e-05	197	158	6	74a2c6cb8fcfe53dd9a2b36492a16c58f38e51c9
ToppCell	5'-Airway_Nasal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.0.0\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	SYNE1 DYNC2I1 ZBBX DNAJA4 KIAA2012 DNAH9	7.38e-05	197	158	6	3bbf068d2ad8196fbc85d3f311a7c54c9aece856
ToppCell	5'-Airway_Nasal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	SYNE1 DYNC2I1 ZBBX DNAJA4 KIAA2012 DNAH9	7.38e-05	197	158	6	87db09f341e2b20eb6e1c3e917cb5c960387b3e9
ToppCell	facs-Brain_Non-Myeloid-Cortex-3m-Macroglial\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GPR37 ENPP2 NEO1 UGT8 GALNT6 ALDH6A1	7.59e-05	198	158	6	731a90f7e68b19e387499d63e3979af78b503b0c
ToppCell	Tracheal-NucSeq-Stromal-Myofibroblastic-Muscle_smooth_systemic_arterial\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	SPEG LRRC32 ADGRA2 FRY AOC3 PLS3	7.59e-05	198	158	6	7dd874b09c81cc512ccc1e9b65f290a5f94d736e
ToppCell	IPF-Endothelial-VE_Peribronchial\|Endothelial / Disease state, Lineage and Cell class	ENPP2 MDN1 SYNJ2 SYNE2 AKAP13 SMAD3	7.59e-05	198	158	6	b8bd1ba268480f54451648e01631b615a3401144
ToppCell	Sigmoid-(1)_T_cell-(14)_Tcm\|Sigmoid / shred on region, Cell_type, and subtype	SYNE1 SESN3 OCRL ALS2CL FBXL18 CDT1	7.80e-05	199	158	6	ec454fa22fb7f50a947bdf4c4bb6f0ba13f62b4c
ToppCell	mild-CD4+_Tcm\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	EML4 ITGA6 STAT1 SYNE2 KMT2A MACF1	7.80e-05	199	158	6	06c8a0e39f7a33736548f04a5e2263334c8541cf
ToppCell	normal_Lung-Endothelial_cells-Tip-like_ECs\|normal_Lung / Location, Cell class and cell subclass	ENPP2 LRRC32 ITGA6 ACE FRY PXDN	7.80e-05	199	158	6	1ae0b47fade7b1cd74c0faabcf4f12f56f62264e
ToppCell	10x_3'_v2v3-Non-neoplastic-Endothelial-Endothelial_mature-Endo_capilar-F\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	LRRC32 ITGA6 ACE ALS2CL ADGRA2 FRY	7.80e-05	199	158	6	236b1417ed0875e98c6ec1ec714003bfce438d65
ToppCell	Tracheal-NucSeq\|Tracheal / Cell types per location group and 10X technology with lineage, and cell group designations	USP34 DENND1A FOCAD FER COG5 TRAPPC9	7.80e-05	199	158	6	94b94b17ca18b8dc27b91da1f2ccf89e03cc7035
ToppCell	Sigmoid-T_cell-Tcm\|Sigmoid / Region, Cell class and subclass	SYNE1 SESN3 OCRL ALS2CL FBXL18 CDT1	7.80e-05	199	158	6	f7c729eaa3c8fd5a05cb6f79cac9b8f199c8092b
ToppCell	Bronchial-10x5prime-Endothelial-Endothelia_vascular-VE_systemic_arterial\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	ENPP2 LRRC32 MYOM3 GRK1 SYNJ2 PLS3	7.80e-05	199	158	6	6a2943a23fdd2ec814662db7c21a0d6804a6cbbc
ToppCell	Transverse-B_cell-B_cell_cycling\|B_cell / Region, Cell class and subclass	AFF2 CRACR2A LRRK2 ORC1 SHCBP1 CDT1	7.80e-05	199	158	6	170ae68963d31f3b821b6f0e8f0c039bea0bc981
ToppCell	LPS_IL1RA-Endothelial-Endothelial\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	ITGA6 RNF213 ACE DST SYNE2 MACF1	8.02e-05	200	158	6	72ea9882a8ed26fa1534aeb6ba0d1897dccc20c5
ToppCell	LPS_IL1RA-Endothelial-Endothelial-Activated_Gen_Cap\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	ENPP2 ITGA6 RNF213 ACE KMT2A MACF1	8.02e-05	200	158	6	2d07237022b409c4fac6fcf99b68c8affb3007cd
ToppCell	Bronchial-NucSeq-Epithelial-Epi_submucosal-gland-SMG_Serous\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	CRACR2A ITGA6 ST3GAL6 SYNJ2 UGT8 GALNT6	8.02e-05	200	158	6	030efc36bbb848da31b0db3f74d46aac9c79cc9b
ToppCell	LPS_IL1RA-Endothelial\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	ITGA6 RNF213 ACE DST SYNE2 MACF1	8.02e-05	200	158	6	5c092b2ecc081b5d04476c56333c338cd89ab984
ToppCell	LPS_only-Endothelial\|LPS_only / Treatment groups by lineage, cell group, cell type	LRRC32 ITGA6 ACE DST SYNE2 MACF1	8.02e-05	200	158	6	81e76508c9050d533853d5fd2f3097b27613d836
ToppCell	mild-MAIT\|mild / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	EML4 ITGA6 SESN1 NEO1 GTF3C1 SYNE2	8.02e-05	200	158	6	1e3ef15ce48b9a19a6ac3e08ea0234a9376e6596
ToppCell	LPS_IL1RA-Endothelial-Endothelial-Activated_Alv_Cap\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	RNF213 ACE FRY DST SYNE2 MACF1	8.02e-05	200	158	6	79e51afb57ca38aacebd0298e5e727b55c0cfff9
ToppCell	VE\|World / Condition, Cell_class and T cell subcluster	RNF213 STAT1 SYNE2 KMT2A MACF1 AKAP13	8.02e-05	200	158	6	8ae7cb81de3ffac5acdf3466d4b516d80cac95d3
Computational	Genes upregulated in subsets of cells of a given type within various tumors	EML4 SYNE1 SYNE2 KMT2A MACF1	5.83e-05	49	92	5	GAVISH_3CA_METAPROGRAM_CD8_T_CELLS_CHROMATIN
Computational	Genes upregulated in subsets of cells of a given type within various tumors	SYNE1 RNF213 DST MACF1 MAP4K4	6.44e-05	50	92	5	GAVISH_3CA_METAPROGRAM_FIBROBLASTS_CAF_4
Drug	plakin	SYNE1 SPTA1 ITGA6 DST SYNE2 MACF1 PLS3	1.40e-06	82	154	7	CID000018752
Disease	Autosomal dominant Emery-Dreifuss muscular dystrophy	SYNE1 SYNE2	1.61e-04	4	154	2	cv:CN293514
Disease	Coughing	TRPA1 ACE	1.61e-04	4	154	2	C0010200
Disease	lung carcinoma (is_marker_for)	ACE MDC1	2.68e-04	5	154	2	DOID:3905 (is_marker_for)
Disease	Autosomal Recessive Emery-Dreifuss Muscular Dystrophy	SYNE1 SYNE2	2.68e-04	5	154	2	C1450051
Disease	Autosomal Dominant Emery-Dreifuss Muscular Dystrophy (disorder)	SYNE1 SYNE2	2.68e-04	5	154	2	C0410190
Disease	Emery-Dreifuss muscular dystrophy	SYNE1 SYNE2	4.00e-04	6	154	2	cv:C0410189
Disease	Muscular Dystrophy, Emery-Dreifuss	SYNE1 SYNE2	4.00e-04	6	154	2	C0410189
Disease	proteinuria (is_implicated_in)	TLR9 ACE	5.59e-04	7	154	2	DOID:576 (is_implicated_in)
Disease	EAR, PATELLA, SHORT STATURE SYNDROME	ORC1 CDT1	5.59e-04	7	154	2	C1868684
Disease	X-Linked Emery-Dreifuss Muscular Dystrophy	SYNE1 SYNE2	5.59e-04	7	154	2	C0751337
Disease	pre-malignant neoplasm (implicated_via_orthology)	ACE SMAD3	9.51e-04	9	154	2	DOID:0060071 (implicated_via_orthology)
Disease	Malignant neoplasm of breast	DPAGT1 COMT SYNE1 ALS2CL STAT1 SYNJ2 ABRAXAS1 BTK SYNE2 PUS1 MACF1 ZFYVE26 DNAH9 PLS3	1.54e-03	1074	154	14	C0006142
Disease	hemoglobin A1 measurement	SPTA1 STEAP2 WDR26 SYNE2 MACF1 AKAP13 CDT1 COG5 DGAT1	1.70e-03	520	154	9	EFO_0007629
Disease	pulmonary fibrosis (implicated_via_orthology)	ACE STAT1	1.73e-03	12	154	2	DOID:3770 (implicated_via_orthology)
Disease	Emery-Dreifuss muscular dystrophy (implicated_via_orthology)	SYNE1 SYNE2	1.73e-03	12	154	2	DOID:11726 (implicated_via_orthology)
Disease	hemolysis	SPTA1 ATAD2B CDT1	1.91e-03	47	154	3	EFO_0009473
Disease	Pain, Migratory	TRPA1 COMT DISC1	2.15e-03	49	154	3	C0751407
Disease	Suffering, Physical	TRPA1 COMT DISC1	2.15e-03	49	154	3	C0751408
Disease	Pain, Crushing	TRPA1 COMT DISC1	2.15e-03	49	154	3	C0458259
Disease	Pain, Splitting	TRPA1 COMT DISC1	2.15e-03	49	154	3	C0458257
Disease	Pain	TRPA1 COMT DISC1	2.15e-03	49	154	3	C0030193
Disease	Radiating pain	TRPA1 COMT DISC1	2.15e-03	49	154	3	C0234254
Disease	Pain, Burning	TRPA1 COMT DISC1	2.15e-03	49	154	3	C0234230
Disease	Ache	TRPA1 COMT DISC1	2.15e-03	49	154	3	C0234238
Disease	type 2 diabetes mellitus (implicated_via_orthology)	AFF2 PIK3CD AOC3 CRTC2	2.27e-03	105	154	4	DOID:9352 (implicated_via_orthology)
Disease	Crohn Disease	LRRK2 TLR9 SMAD3	2.28e-03	50	154	3	C0010346
Disease	eosinophil measurement	USP34 ARSB PXDN SESN2	2.51e-03	108	154	4	EFO_0803540
Disease	episodic memory	SYNGAP1 RXFP2 UGT8	2.55e-03	52	154	3	EFO_0004333
Disease	corneal resistance factor	SYNJ2 TTLL6 FER LRP6 KMT2A AKAP13 GALNT6 SMAD3	2.63e-03	451	154	8	EFO_0010067
Disease	Down syndrome (implicated_via_orthology)	SYNJ2 DOP1B	2.72e-03	15	154	2	DOID:14250 (implicated_via_orthology)
Disease	mean platelet volume	TEX2 SPTA1 LRRK2 ITGA6 DYNC2I1 NBPF6 FRY FBXL18 ST3GAL6 TESK2 ATAD2B SYNE2 PLS3	2.75e-03	1020	154	13	EFO_0004584
Disease	diabetic retinopathy (is_marker_for)	ACE F13A1 AOC3	2.85e-03	54	154	3	DOID:8947 (is_marker_for)
Disease	Small cell carcinoma of lung	FER KMT2A RASSF8	2.85e-03	54	154	3	C0149925
Disease	cancer (implicated_via_orthology)	SNF8 CAB39 ITGA6 DST PIK3CD MACF1	2.91e-03	268	154	6	DOID:162 (implicated_via_orthology)
Disease	teratocarcinoma-derived growth factor 1 measurement	ALS2CL KMT2A	3.10e-03	16	154	2	EFO_0008297
Disease	macula measurement	DENND1A SYNGAP1 ATAD2B TRPM1 COG5	3.20e-03	189	154	5	EFO_0008375
Disease	Night blindness, congenital stationary	GRK1 TRPM1	3.50e-03	17	154	2	C0339535
Disease	chronic lymphocytic leukemia	GPR37 SFI1 ARSB SMAD3	3.56e-03	119	154	4	EFO_0000095
Disease	Schizophrenia	COMT DISC1	3.92e-03	18	154	2	cv:C0036341
Disease	Chronic myeloproliferative disorder	ORC1 CDT1	4.37e-03	19	154	2	C1292778
Disease	Fetal Growth Retardation	COMT ORC1	4.83e-03	20	154	2	C0015934
Disease	attention deficit hyperactivity disorder (is_implicated_in)	DCDC2 COMT	4.83e-03	20	154	2	DOID:1094 (is_implicated_in)
Disease	eosinophil count	LRRC32 SESN3 ITGA6 SESN1 GTF3C4 STAT1 ITPR3 MDN1 PXDN ST3GAL6 PIK3CD AKAP13 SESN2 KIAA2012 MAP4K4 SMAD3	4.93e-03	1488	154	16	EFO_0004842

Protein segments in the cluster

Peptide	Gene	Start	Entry
PQIIKHKALDLDDRW	ABRAXAS1	341	Q6UWZ7
QLLEFLDVQKHLWPL	ALS2CL	801	Q60I27
LDVQKHLWPLKDLTL	ALS2CL	806	Q60I27
SLVPRLHWLLVEDAE	B3GAT3	101	O94766
FKPLLDWLRTENELH	ACE	1201	P12821
PTEELRKRWIHQLKN	BTK	116	Q06187
LVDEHLLWLAQREDK	ADGRA2	496	Q96PE1
LQEPLLHDIRKSVDW	CTSL3P	51	Q5NE16
PLRDHENLKNLWVKI	AFF2	791	P51816
LVLAFRHLKLPTEWN	AKAP13	136	Q12802
RHLKLPTEWNVLGTD	AKAP13	141	Q12802
LDLLHALQERVLKWP	ARHGEF33	321	A8MVX0
EKHLLLLSELLPDWL	CDT1	496	Q9H211
LLLSDLRQRPEWDKH	ACOT11	441	Q8WXI4
IRHEPLAKIILWSEQ	CAB39	151	Q9Y376
QLWLQLKKEEPHLLS	CRACR2A	181	Q9BSW2
LVIFPEKHWLSLEKL	DNAJA4	326	Q8WW22
EKHWLSLEKLPQLEA	DNAJA4	331	Q8WW22
ERLLKLAVPNHLIWL	DGAT1	321	O75907
LKVLEEWKTHLIPSL	DISC1	746	Q9NRI5
EKTLSPRELWHLVHQ	GRAMD1A	201	Q96CP6
ELLVNHKALDPARWT	AOC3	246	Q16853
RPHVLLKVLQDLRIW	CCDC60	491	Q8IWA6
RWLNKHLKTLLTPDD	NBPF4	121	Q96M43
TLIEKWRDTERHLAP	RASSF8	41	Q8NHQ8
EEQHWTLLKFDTLLP	RABEPK	276	Q7Z6M1
DEWLKVALHDLPENL	RFX4	291	Q33E94
TWDVKDTLLRLRHPL	HDHD3	11	Q9BSH5
VLVDVLHWPELLFLE	ITPR3	1616	Q14573
LWRLENGELEHIRPK	PAFAH1B3	81	Q15102
LPWARQELHKLLDKD	ARL10	161	Q8N8L6
LDAWRVPLKVSAELL	PAXIP1	811	Q6ZW49
KWLPELVEHAKNLRV	ALDH6A1	331	Q02252
WLRNKILHNDPEVEK	MAP4K4	996	O95819
HKLIWLPLREAFEEL	MDN1	721	Q9NU22
KLLVVSLEEAWPLHG	MDC1	561	Q14676
ELSHLQELLRKWTPR	MTMR11	661	A4FU01
LWRLKTPEEHELETG	HIPK1	436	Q86Z02
VLEPAVSARLLEHLW	HES2	106	Q9Y543
WLTDTERHLLASKPL	DST	6501	Q03001
DHWLPLEIRDKLNSS	LIPT1	316	Q9Y234
ILQIHTRDWNPKLSD	ATAD2B	581	Q9ULI0
IWSEHPLQIELLKLL	DOP1B	1431	Q9Y3R5
EVKLELHPLQNRWAL	EIF4E1B	56	A6NMX2
DLEVKIRDWHLKQSP	KRT13	131	P13646
QEWQLHRTGLLKIPE	LRRC39	86	Q96DD0
RLLLQEALWPEGKLH	DYNC2I1	1051	Q8WVS4
AWAEPHLERLLREKL	COL23A1	86	Q86Y22
ERELAWLKEHLSQLE	ETNK2	226	Q9NVF9
DVLNLRWRHKLLLPT	DPAGT1	116	Q9H3H5
KLSPEELLLRWANFH	PLS3	266	P13797
RKDELPRLQLEWIDS	PDE11A	861	Q9HCR9
VKWAVEEPRLHNQLL	GGTLC1	151	Q9BX51
DHEATAWILINPLRK	IGFBPL1	221	Q8WX77
RGPWRKLDLELHTLQ	KIAA2012	96	Q0VF49
REPLTELKHLWENLG	MACF1	2321	O94854
VLVWKDLDSPRALAL	LRP6	741	O75581
LSKIWDLPLDELHLN	LRRK2	1291	Q5S007
PLKETLRNVWVHLDG	F13A1	656	P00488
HWQLQPEDKRLLLVG	ITGA6	51	P23229
DIIREPLTELKHLWE	MACF1	6191	Q9UPN3
IQLHWRPDIALTLSL	PKD1L2	1196	Q7Z442
DDQRLLLPHWAKVVL	GBA	321	P04062
TWLDLRENKLLHFPD	LRRC32	246	Q14392
LFDWPTHKEARLVVL	ORC1	636	Q13415
QWLDDHPSEKDRLLL	COG5	786	Q9UP83
DHWKDRYLPDTLLLE	COMT	191	P21964
PLVIFHELTKKWLLE	GPR37	316	O15354
LTHLKDLIAWQIPFL	DOCK2	1566	Q92608
RESWVREKVLFLLHP	C6orf141	81	Q5SZD1
HEAVLKLQDWELRLL	FER	11	P16591
EGLKELVHLEWLNLA	CEP97	96	Q8IW35
IEENLLDDKHLLKPW	CRTC2	216	Q53ET0
HGWLEPLLARIAEDK	GALNT6	276	Q8NCL4
DSLKHREWGVNDPLL	FUT11	366	Q495W5
KLIEWLPQNDLLGHS	UGT8	336	Q16880
TDWILERDPHEEILK	CETN3	91	O15182
WKEPEELKQLLDLEL	CSAD	46	Q9Y600
DQILLHDLEWLKNDR	MACC1	161	Q6ZN28
GVKNRELIHISDWLP	ARSB	341	P15848
ELIHISDWLPTLVKL	ARSB	346	P15848
NQWNELLETLHKLPI	DENND1A	126	Q8TEH3
ALLVHDLQKLDALEW	GBF1	1571	Q92538
ERHPAEWRLALEKEL	KMT2A	1626	Q03164
RKIILWDHDLNPERE	EML4	531	Q9HC35
RELANITHDGPKWIL	DNAH9	2211	Q9NYC9
LPWLHNIELVDSRLL	FRY	1361	Q5TBA9
LQSAEKHLPALELWK	GRK1	76	Q15835
LHALPLKEDLEEWVT	IPO4	986	Q8TEX9
ILTILQWLTLPDHER	ENPP2	286	Q13822
LLIPRKTLNQWDHVL	DCDC2	156	Q9UHG0
LLISAPLWIKHISDE	FOCAD	1466	Q5VW36
LILDHQWELEKLSLL	KIF1A	1371	Q12756
KELEIHLWPSLEALD	LINGO4	231	Q6UY18
QKKERELLPLLHAAW	SFI1	431	A8K8P3
EINKLLAHRPWLITK	SESN2	161	P58004
ELNKVLAHRPWLITK	SESN1	166	Q9Y6P5
ILELIKKHLLPLWND	STAT1	561	P42224
EKPHLNLWLEAPDLL	PIH1D1	206	Q9NWS0
KLHLEQLDERWRDLP	SYNE1	1736	Q8NF91
EPWLEIKHLHESLLQ	SYNE2	2221	Q8WXH0
TLLRPQLKLHWEDFD	SYNJ2	351	O15056
RWLNKHLKTLLTPDD	NBPF5P	121	Q86XG9
RWLNKHLKTLLTPDD	NBPF6	121	Q5VWK0
HSTPLWLLLSRLEEK	PRPF6	741	O94906
WLIDDILEKINSHLP	PUS1	161	Q9Y606
WSLLKNLPFLEHLEL	FBXL18	476	Q96ME1
PDLWIHHERLELKPI	NEO1	1161	Q92859
QRLLVWEKPLHSLVT	RETREG2	71	Q8NC44
LTAFKPHDLRWLLEL	ST3GAL6	186	Q9Y274
KDLHQLTWLILDDNP	RXFP2	206	Q8WXD0
LWDLRHLLVGKILID	STEAP2	101	Q8NFT2
LDLKEHRLPLQELWV	SHCBP1	166	Q8NEM2
PLQVPKEIWLLVDHL	OCRL	731	Q01968
DELKIPIRSWHDIEK	SEC23B	306	Q15437
QVLEHLLKEGLAWLD	SNF8	211	Q96H20
QHAWLPLTIEIKDRL	TCL1A	31	P56279
IWQHLELIDGRPLKT	CNBD2	306	Q96M20
PILWHFLQKEAELRL	RNF213	4766	Q63HN8
HRDLKLENLLLDKWE	TSSK4	146	Q6SA08
HWLRPALHTKKQILE	ZSCAN10	16	Q96SZ4
ELHTSLEKKLPLWFL	TRPA1	981	O75762
LLELRLQNWAHEKDP	VPS11	626	Q9H270
WLRPEVHSKEQILEL	ZSCAN30	76	Q86W11
KWLRPEIHSKEQILE	ZNF287	76	Q9HBT7
LHLDVKPENLLVWDG	SPEG	1716	Q15772
TLHALLWEVLPQLSK	SYNGAP1	691	Q96PV0
WLPADVIFLAKILHL	SLC27A5	86	Q9Y2P5
WSLHFLPKLEVLDLA	TLR9	671	Q9NR96
IELHLNGPLQWLDKV	SMAD3	396	P84022
NEINKLLAHRPWLIT	SESN3	156	P58005
LWLRPDLHTKEQILD	ZSCAN5B	71	A6NJL1
QWLRPEIHSKKHILE	ZNF75CP	76	Q92670
NRIATELLKLNPHWD	PXDN	996	Q92626
LLLEHLLSSWEQIPK	TMEM214	416	Q6NUQ4
LWLRPDLHTKEQILD	ZSCAN5A	71	Q9BUG6
HFPEALARLLLVTKW	PIK3CD	541	O00329
WLRHNVDLKLKELLE	PHEX	106	P78562
DPKWLDVIEKDLHRQ	TBC1D10B	396	Q4KMP7
LRHLWDLLLELTLEK	SPTA1	136	P02549
LWKPTHEDSKILLVD	GTF3C4	596	Q9UKN8
FDILLDHKLKPWLLE	TTLL6	346	Q8N841
DPRKLHWLFELLLES	PSME4	1436	Q14997
DWQLELPKLLISVHG	TRPM1	91	Q7Z4N2
WLKASLPSIQEELRH	YY1AP1	376	Q9H869
WLRPEIHTKKQIIEL	ZNF215	76	Q9UL58
LDPRTGQKLVEWHQL	UBXN7	231	O94888
LVLEHLQLAPLQWDV	TRAPPC9	1006	Q96Q05
LSILPKELQGWVREH	ZSCAN9	101	O15535
PFVLHLEKTIAWDLL	USP31	476	Q70CQ4
DHLQDWLKKLTLLIP	USP34	1651	Q70CQ2
IWQVDPDTHLLKLLK	WDR26	381	Q9H7D7
LRHWNTRSLDIKEPE	TEX2	531	Q8IWB9
PWLLHSVRLKDREDA	GTF3C1	1811	Q12789
LLDSNLHLPWTVRVK	TESK2	141	Q96S53
ILELAWKSLPEADLH	WDR87	2846	Q6ZQQ6
HWPLQNALVDLIRKA	ZFYVE26	186	Q68DK2
LWLRPDLHTKEQILD	ZSCAN5C	71	A6NGD5
ALILENFLHKWDPRS	TPCN2	691	Q8NHX9
IWREPLNIELKEDIL	ZBBX	301	A8MT70
DILLDHKLKPWLLEV	TTLL13	376	A6NNM8
RHVLVNSIWPLKALD	LRRIQ3	141	A6PVS8
QPLLKRVHANVDLWD	MYO7B	1651	Q6PIF6
TTLDEIWLHILDPKD	MYOM3	1271	Q5VTT5