Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctiontransmembrane signaling receptor activity

TNFRSF25 ERBB4 ABCA1 ZNF219 HMCN2 EDAR FZD5 LRP5 GPRC5D LTBP1 NOTCH1 NOTCH2

6.32e-0513534812GO:0004888
GeneOntologyMolecularFunctionextracellular matrix structural constituent

HMCN2 CILP LAMA2 LTBP1 BMPER

8.65e-05188485GO:0005201
GeneOntologyMolecularFunctionWnt receptor activity

FZD5 LRP5

7.52e-0417482GO:0042813
GeneOntologyMolecularFunctionligase activity

TARS3 CAD IARS1 SLC27A5

8.04e-04174484GO:0016874
GeneOntologyMolecularFunctionsphingolipid transporter activity

ABCA1 ATP10B

1.05e-0320482GO:0046624
GeneOntologyMolecularFunctionphosphatidylcholine transporter activity

ABCA1 ATP10B

1.05e-0320482GO:0008525
GeneOntologyMolecularFunctiongap junction channel activity

GJB1 GJB4

1.64e-0325482GO:0005243
GeneOntologyMolecularFunctionNotch binding

DLL4 NOTCH1

1.91e-0327482GO:0005112
GeneOntologyMolecularFunctionATPase-coupled intramembrane lipid transporter activity

ABCA1 ATP10B

2.06e-0328482GO:0140326
GeneOntologyMolecularFunctionprotein kinase activity

ERBB4 CAD LTBP1 MAP3K21 TSSK4 MAP2K7

3.01e-03600486GO:0004672
GeneOntologyMolecularFunctionWnt-protein binding

FZD5 LRP5

3.02e-0334482GO:0017147
GeneOntologyMolecularFunctionwide pore channel activity

GJB1 GJB4

3.57e-0337482GO:0022829
GeneOntologyMolecularFunctionligase activity, forming carbon-oxygen bonds

TARS3 IARS1

4.58e-0342482GO:0016875
GeneOntologyMolecularFunctionaminoacyl-tRNA ligase activity

TARS3 IARS1

4.58e-0342482GO:0004812
GeneOntologyBiologicalProcesssemi-lunar valve development

DLL4 SLIT3 NOTCH1 NOTCH2

5.97e-0650494GO:1905314
GeneOntologyBiologicalProcesspositive regulation of MAPK cascade

ERBB4 EDAR FZD5 ADAM9 BMPER MAP2K7 NOTCH1 NOTCH2 TP73

6.86e-06571499GO:0043410
GeneOntologyBiologicalProcessheart valve morphogenesis

DLL4 SLIT3 NOTCH1 NOTCH2

1.51e-0563494GO:0003179
GeneOntologyBiologicalProcesscellular response to tumor cell

NOTCH1 NOTCH2

1.66e-053492GO:0071228
GeneOntologyBiologicalProcessheart valve development

DLL4 SLIT3 NOTCH1 NOTCH2

3.52e-0578494GO:0003170
GeneOntologyBiologicalProcessMAPK cascade

ERBB4 EDAR FZD5 ADAM9 BMPER MAP3K21 MAP2K7 NOTCH1 NOTCH2 TP73

5.48e-059304910GO:0000165
GeneOntologyBiologicalProcessapoptotic process involved in morphogenesis

FZD5 LRP5 NOTCH1

5.95e-0532493GO:0060561
GeneOntologyBiologicalProcesscardiac atrium morphogenesis

DLL4 NOTCH1 NOTCH2

7.82e-0535493GO:0003209
GeneOntologyBiologicalProcessaortic valve morphogenesis

DLL4 SLIT3 NOTCH1

1.08e-0439493GO:0003180
GeneOntologyBiologicalProcessregulation of MAPK cascade

ERBB4 EDAR FZD5 ADAM9 BMPER MAP2K7 NOTCH1 NOTCH2 TP73

1.11e-04815499GO:0043408
GeneOntologyBiologicalProcesscardiac atrium development

DLL4 NOTCH1 NOTCH2

1.36e-0442493GO:0003230
GeneOntologyBiologicalProcesscardiac chamber development

DLL4 SLIT3 LTBP1 NOTCH1 NOTCH2

1.44e-04212495GO:0003205
GeneOntologyBiologicalProcesscellular response to growth factor stimulus

ERBB4 CAD CILP DLL4 ADAM9 LTBP1 BMPER NOTCH1 NOTCH2

1.53e-04850499GO:0071363
GeneOntologyBiologicalProcessaortic valve development

DLL4 SLIT3 NOTCH1

1.78e-0446493GO:0003176
GeneOntologyBiologicalProcessapoptotic process involved in development

FZD5 LRP5 NOTCH1

1.90e-0447493GO:1902742
GeneOntologyBiologicalProcesspositive regulation of developmental pigmentation

HPS4 ADAMTS20

1.97e-049492GO:0048087
GeneOntologyBiologicalProcessatrioventricular node development

NOTCH1 NOTCH2

1.97e-049492GO:0003162
GeneOntologyBiologicalProcesspericardium morphogenesis

DLL4 NOTCH1

1.97e-049492GO:0003344
GeneOntologyBiologicalProcessresponse to growth factor

ERBB4 CAD CILP DLL4 ADAM9 LTBP1 BMPER NOTCH1 NOTCH2

2.04e-04883499GO:0070848
GeneOntologyBiologicalProcesscellular response to biotic stimulus

ABCA1 FZD5 ADAM9 MAP2K7 NOTCH1 NOTCH2

2.14e-04364496GO:0071216
GeneOntologyBiologicalProcesspositive regulation of ERK1 and ERK2 cascade

ERBB4 BMPER MAP2K7 NOTCH1 NOTCH2

2.57e-04240495GO:0070374
GeneOntologyBiologicalProcesscardiac septum development

SLIT3 LTBP1 NOTCH1 NOTCH2

2.88e-04134494GO:0003279
GeneOntologyBiologicalProcessheart development

ERBB4 CAD DLL4 SLIT3 LTBP1 NOTCH1 NOTCH2 TP73

3.77e-04757498GO:0007507
GeneOntologyBiologicalProcesscirculatory system development

ERBB4 CAD DLL4 FZD5 SLIT3 LRP5 LTBP1 BMPER NOTCH1 NOTCH2 TP73

4.61e-0414424911GO:0072359
GeneOntologyBiologicalProcessresponse to laminar fluid shear stress

ABCA1 ADAM9

4.94e-0414492GO:0034616
GeneOntologyBiologicalProcessnegative regulation of hematopoietic progenitor cell differentiation

N4BP2L2 NOTCH1

4.94e-0414492GO:1901533
GeneOntologyBiologicalProcessleft/right axis specification

NOTCH1 NOTCH2

4.94e-0414492GO:0070986
GeneOntologyBiologicalProcessregulation of cardiac muscle cell proliferation

ERBB4 NOTCH1 TP73

4.96e-0465493GO:0060043
GeneOntologyBiologicalProcessaxon guidance

HMCN2 SLIT3 LAMA2 NOTCH1 NOTCH2

5.64e-04285495GO:0007411
GeneOntologyBiologicalProcessregulation of developmental pigmentation

HPS4 ADAMTS20

5.69e-0415492GO:0048070
GeneOntologyBiologicalProcessneuron projection guidance

HMCN2 SLIT3 LAMA2 NOTCH1 NOTCH2

5.73e-04286495GO:0097485
GeneOntologyBiologicalProcesscardiac chamber morphogenesis

DLL4 SLIT3 NOTCH1 NOTCH2

5.76e-04161494GO:0003206
GeneOntologyBiologicalProcesscardiac ventricle development

DLL4 SLIT3 LTBP1 NOTCH1

5.76e-04161494GO:0003231
GeneOntologyBiologicalProcesstransforming growth factor beta receptor superfamily signaling pathway

CILP ADAM9 LTBP1 BMPER NOTCH1 NOTCH2

6.22e-04445496GO:0141091
GeneOntologyBiologicalProcesscamera-type eye morphogenesis

FZD5 LRP5 NOTCH1 NOTCH2

7.22e-04171494GO:0048593
GeneOntologyBiologicalProcessmorphogenesis of an epithelial sheet

DLL4 NOTCH1 NOTCH2

7.25e-0474493GO:0002011
GeneOntologyBiologicalProcessregulation of pigmentation

HPS4 ADAMTS20

7.35e-0417492GO:0120305
GeneOntologyBiologicalProcessventricular trabecula myocardium morphogenesis

DLL4 NOTCH1

7.35e-0417492GO:0003222
GeneOntologyBiologicalProcessgland morphogenesis

EDAR LRP5 NOTCH1 NOTCH2

8.39e-04178494GO:0022612
GeneOntologyBiologicalProcesspositive regulation of neural precursor cell proliferation

DLL4 NOTCH1 NOTCH2

9.10e-0480493GO:2000179
GeneOntologyBiologicalProcessaorta development

DLL4 LTBP1 NOTCH1

9.10e-0480493GO:0035904
GeneOntologyBiologicalProcesscell surface receptor protein serine/threonine kinase signaling pathway

CILP ADAM9 LTBP1 BMPER NOTCH1 NOTCH2

9.42e-04482496GO:0007178
GeneOntologyBiologicalProcessappendage morphogenesis

ZNF219 LRP5 NOTCH1 NOTCH2

9.69e-04185494GO:0035107
GeneOntologyBiologicalProcesslimb morphogenesis

ZNF219 LRP5 NOTCH1 NOTCH2

9.69e-04185494GO:0035108
GeneOntologyBiologicalProcesscardiac muscle cell proliferation

ERBB4 NOTCH1 TP73

9.78e-0482493GO:0060038
GeneOntologyBiologicalProcesspulmonary valve morphogenesis

NOTCH1 NOTCH2

1.02e-0320492GO:0003184
GeneOntologyBiologicalProcesscardiac muscle tissue development

ERBB4 DLL4 NOTCH1 NOTCH2 TP73

1.05e-03327495GO:0048738
GeneOntologyBiologicalProcesscardiac septum morphogenesis

SLIT3 NOTCH1 NOTCH2

1.24e-0389493GO:0060411
GeneOntologyBiologicalProcessventricular septum development

SLIT3 LTBP1 NOTCH1

1.32e-0391493GO:0003281
GeneOntologyBiologicalProcessregulation of transmembrane receptor protein serine/threonine kinase signaling pathway

CILP LTBP1 BMPER NOTCH1 NOTCH2

1.36e-03347495GO:0090092
GeneOntologyBiologicalProcesseye morphogenesis

FZD5 LRP5 NOTCH1 NOTCH2

1.39e-03204494GO:0048592
GeneOntologyBiologicalProcessstriated muscle tissue development

ERBB4 DLL4 NOTCH1 NOTCH2 TP73

1.40e-03349495GO:0014706
GeneOntologyCellularComponentexternal encapsulating structure

FCGBP HMCN2 CILP LAMA2 ADAMTS20 LTBP1 BMPER PKHD1L1

1.15e-04658488GO:0030312
GeneOntologyCellularComponentextracellular matrix

FCGBP HMCN2 CILP LAMA2 ADAMTS20 LTBP1 BMPER

6.98e-04656487GO:0031012
GeneOntologyCellularComponentconnexin complex

GJB1 GJB4

1.16e-0322482GO:0005922
GeneOntologyCellularComponentcollagen-containing extracellular matrix

HMCN2 CILP LAMA2 ADAMTS20 LTBP1 BMPER

1.28e-03530486GO:0062023
MousePhenoabnormal induced retina neovascularization

DLL4 ADAM9 BMPER

2.79e-0521403MP:0009660
MousePhenoabnormal myocardial trabeculae morphology

ERBB4 DLL4 SLIT3 NOTCH1 NOTCH2

5.33e-05144405MP:0002189
DomainEGF-like_dom

FCGBP HMCN2 DLL4 ADAM9 SLIT3 LAMA2 LRP5 LTBP1 NOTCH1 NOTCH2

6.21e-102494810IPR000742
DomainEGF

FCGBP DLL4 ADAM9 SLIT3 LAMA2 LRP5 LTBP1 NOTCH1 NOTCH2

7.42e-09235489SM00181
DomainEGF_1

HMCN2 DLL4 ADAM9 SLIT3 LAMA2 LRP5 LTBP1 NOTCH1 NOTCH2

1.51e-08255489PS00022
DomainEGF-like_CS

HMCN2 DLL4 ADAM9 SLIT3 LAMA2 LRP5 LTBP1 NOTCH1 NOTCH2

1.85e-08261489IPR013032
DomainEGF_2

HMCN2 DLL4 ADAM9 SLIT3 LAMA2 LRP5 LTBP1 NOTCH1 NOTCH2

2.10e-08265489PS01186
DomainEGF-like_Ca-bd_dom

HMCN2 DLL4 SLIT3 LRP5 LTBP1 NOTCH1 NOTCH2

2.82e-08124487IPR001881
DomainEGF_3

HMCN2 DLL4 ADAM9 SLIT3 LRP5 LTBP1 NOTCH1 NOTCH2

1.36e-07235488PS50026
DomainGrowth_fac_rcpt_

ERBB4 HMCN2 DLL4 SLIT3 LTBP1 NOTCH1 NOTCH2

1.37e-07156487IPR009030
DomainEGF_CA

HMCN2 SLIT3 LRP5 LTBP1 NOTCH1 NOTCH2

1.95e-0799486PS01187
DomainEGF-type_Asp/Asn_hydroxyl_site

HMCN2 DLL4 SLIT3 LTBP1 NOTCH1 NOTCH2

2.93e-07106486IPR000152
DomainEGF_CA

HMCN2 DLL4 SLIT3 LTBP1 NOTCH1 NOTCH2

6.73e-07122486SM00179
DomainEGF

DLL4 SLIT3 LRP5 LTBP1 NOTCH1 NOTCH2

8.14e-07126486PF00008
DomainEGF_Ca-bd_CS

HMCN2 SLIT3 LTBP1 NOTCH1 NOTCH2

4.89e-0697485IPR018097
DomainASX_HYDROXYL

HMCN2 DLL4 LTBP1 NOTCH1 NOTCH2

5.67e-06100485PS00010
DomainDUF3454

NOTCH1 NOTCH2

1.94e-053482PF11936
DomainDUF3454_notch

NOTCH1 NOTCH2

1.94e-053482IPR024600
DomainDUF3454

NOTCH1 NOTCH2

1.94e-053482SM01334
DomainNotch

NOTCH1 NOTCH2

3.87e-054482IPR008297
DomainNODP

NOTCH1 NOTCH2

3.87e-054482PF07684
DomainNotch_NODP_dom

NOTCH1 NOTCH2

3.87e-054482IPR011656
DomainNotch_NOD_dom

NOTCH1 NOTCH2

3.87e-054482IPR010660
DomainNOD

NOTCH1 NOTCH2

3.87e-054482PF06816
DomainNOD

NOTCH1 NOTCH2

3.87e-054482SM01338
DomainNODP

NOTCH1 NOTCH2

3.87e-054482SM01339
DomainLNR

NOTCH1 NOTCH2

6.44e-055482PS50258
DomainEGF_CA

HMCN2 LTBP1 NOTCH1 NOTCH2

6.99e-0586484PF07645
DomainNotch_dom

NOTCH1 NOTCH2

1.35e-047482IPR000800
DomainNotch

NOTCH1 NOTCH2

1.35e-047482PF00066
DomainNL

NOTCH1 NOTCH2

1.35e-047482SM00004
DomainTIL

FCGBP BMPER

4.20e-0412482PF01826
DomainC8

FCGBP BMPER

4.20e-0412482PF08742
DomainEGF_extracell

DLL4 ADAM9 NOTCH1

4.92e-0460483IPR013111
DomainEGF_2

DLL4 ADAM9 NOTCH1

4.92e-0460483PF07974
DomainUnchr_dom_Cys-rich

FCGBP BMPER

4.95e-0413482IPR014853
DomainC8

FCGBP BMPER

4.95e-0413482SM00832
DomainTIL_dom

FCGBP BMPER

5.77e-0414482IPR002919
DomainVWD

FCGBP BMPER

7.58e-0416482SM00216
DomainVWF_type-D

FCGBP BMPER

7.58e-0416482IPR001846
DomainVWFD

FCGBP BMPER

7.58e-0416482PS51233
DomainVWD

FCGBP BMPER

7.58e-0416482PF00094
DomainCONNEXINS_1

GJB1 GJB4

1.08e-0319482PS00407
DomainCONNEXINS_2

GJB1 GJB4

1.19e-0320482PS00408
DomainConnexin

GJB1 GJB4

1.19e-0320482IPR000500
DomainConnexin_CCC

GJB1 GJB4

1.19e-0320482IPR019570
DomainConnexin_N

GJB1 GJB4

1.19e-0320482IPR013092
DomainConnexin

GJB1 GJB4

1.19e-0320482PF00029
DomainConnexin_CCC

GJB1 GJB4

1.19e-0320482SM01089
DomainConnexin_CS

GJB1 GJB4

1.19e-0320482IPR017990
DomainCNX

GJB1 GJB4

1.19e-0320482SM00037
DomainhEGF

NOTCH1 NOTCH2

2.34e-0328482PF12661
DomainTNFR_NGFR_1

TNFRSF25 EDAR

2.51e-0329482PS00652
DomainTNFR_NGFR_2

TNFRSF25 EDAR

2.51e-0329482PS50050
DomainDeath

TNFRSF25 EDAR

3.25e-0333482PF00531
DomainTNFR/NGFR_Cys_rich_reg

TNFRSF25 EDAR

3.25e-0333482IPR001368
DomainDeath_domain

TNFRSF25 EDAR

4.29e-0338482IPR000488
DomainVWC

FCGBP BMPER

4.29e-0338482SM00214
DomainDEATH_DOMAIN

TNFRSF25 EDAR

4.29e-0338482PS50017
DomainLAM_G_DOMAIN

SLIT3 LAMA2

4.29e-0338482PS50025
DomainPeptidase_M12B_N

ADAM9 ADAMTS20

4.51e-0339482IPR002870
DomainPep_M12B_propep

ADAM9 ADAMTS20

4.51e-0339482PF01562
DomainDISINTEGRIN_1

ADAM9 ADAMTS20

4.74e-0340482PS00427
DomainReprolysin

ADAM9 ADAMTS20

4.74e-0340482PF01421
DomainLaminin_G_2

SLIT3 LAMA2

4.74e-0340482PF02210
DomainADAM_MEPRO

ADAM9 ADAMTS20

4.74e-0340482PS50215
DomainDISINTEGRIN_2

ADAM9 ADAMTS20

4.74e-0340482PS50214
DomainPeptidase_M12B

ADAM9 ADAMTS20

4.74e-0340482IPR001590
DomainDisintegrin_dom

ADAM9 ADAMTS20

4.98e-0341482IPR001762
PathwayKEGG_MEDICUS_REFERENCE_NOTCH_SIGNALING_PATHWAY

DLL4 NOTCH1 NOTCH2

5.94e-0613403M47423
PathwayWP_OSTEOBLAST_DIFFERENTIATION_AND_RELATED_DISEASES

DLL4 FZD5 LRP5 NOTCH1 NOTCH2

1.96e-05118405M39852
PathwayWP_CANONICAL_AND_NONCANONICAL_NOTCH_SIGNALING

DLL4 NOTCH1 NOTCH2

5.91e-0527403M39545
PathwayWP_BREAST_CANCER_PATHWAY

DLL4 FZD5 LRP5 NOTCH1 NOTCH2

7.05e-05154405M39739
PathwayREACTOME_DEFECTIVE_LFNG_CAUSES_SCDO3

NOTCH1 NOTCH2

7.81e-055402M27411
PathwayWP_EPITHELIAL_TO_MESENCHYMAL_TRANSITION_IN_COLORECTAL_CANCER

DLL4 FZD5 LRP5 NOTCH1 NOTCH2

8.70e-05161405M39770
PathwayWP_HAIR_FOLLICLE_DEVELOPMENT_CYTODIFFERENTIATION_STAGE_3_OF_3

ADAMTS20 GPRC5D NOTCH1 NOTCH2

1.04e-0487404M39465
PathwayREACTOME_PRE_NOTCH_PROCESSING_IN_THE_ENDOPLASMIC_RETICULUM

NOTCH1 NOTCH2

1.17e-046402M27068
PathwayWP_NEURAL_CREST_DIFFERENTIATION

GJB1 DLL4 NOTCH1 NOTCH2

1.59e-0497404MM15926
PathwayREACTOME_SIGNALING_BY_NOTCH1_T_7_9_NOTCH1_M1580_K2555_TRANSLOCATION_MUTANT

DLL4 NOTCH1

1.63e-047402M27199
PathwayWP_NEURAL_CREST_DIFFERENTIATION

GJB1 DLL4 NOTCH1 NOTCH2

1.86e-04101404M39448
PathwayREACTOME_SIGNALING_BY_RNF43_MUTANTS

FZD5 LRP5

2.17e-048402M27433
PathwayWP_NOTCH_SIGNALING_WP268

DLL4 NOTCH1 NOTCH2

2.77e-0445403M39571
PathwayWP_NOTCH_SIGNALING_PATHWAY

DLL4 NOTCH1 NOTCH2

2.95e-0446403MM15971
PathwayKEGG_NOTCH_SIGNALING_PATHWAY

DLL4 NOTCH1 NOTCH2

3.15e-0447403M7946
PathwayKEGG_MEDICUS_REFERENCE_NOTCH_PROTEOLYTIC_ACTIVATION

NOTCH1 NOTCH2

4.25e-0411402M47865
PathwayBIOCARTA_HES_PATHWAY

NOTCH1 NOTCH2

5.09e-0412402MM1562
PathwayBIOCARTA_HES_PATHWAY

NOTCH1 NOTCH2

5.09e-0412402M22042
PathwayKEGG_MEDICUS_PATHOGEN_HPV_E6_TO_NOTCH_SIGNALING_PATHWAY_N00380

NOTCH1 NOTCH2

5.09e-0412402M47532
PathwayKEGG_MEDICUS_PATHOGEN_HPV_E6_TO_NOTCH_SIGNALING_PATHWAY_N00381

NOTCH1 NOTCH2

5.09e-0412402M47533
PathwayKEGG_MEDICUS_REFERENCE_MLK_JNK_SIGNALING_PATHWAY

MAP3K21 MAP2K7

5.09e-0412402M47929
PathwayKEGG_MEDICUS_PATHOGEN_HPV_E6_TO_NOTCH_SIGNALING_PATHWAY_N00382

NOTCH1 NOTCH2

6.00e-0413402M47534
PathwayPID_NOTCH_PATHWAY

DLL4 NOTCH1 NOTCH2

6.16e-0459403M17
PathwayWP_NOTCH_SIGNALING_WP61

DLL4 NOTCH1 NOTCH2

6.80e-0461403M39540
PathwayREACTOME_DISEASES_OF_GLYCOSYLATION

ADAMTS20 ALG11 NOTCH1 NOTCH2

6.99e-04143404M27275
PathwayKEGG_MEDICUS_REFERENCE_WNT_SIGNALING_MODULATION_SOST_LRP4

FZD5 LRP5

6.99e-0414402M47834
PathwayREACTOME_SIGNALING_BY_NOTCH1_HD_DOMAIN_MUTANTS_IN_CANCER

DLL4 NOTCH1

8.05e-0415402M27202
PathwayKEGG_MEDICUS_VARIANT_NOTCH_OVEREXPRESSION_TO_NOTCH_SIGNALING_PATHWAY

DLL4 NOTCH1

9.19e-0416402M47424
PathwayREACTOME_DISEASES_ASSOCIATED_WITH_O_GLYCOSYLATION_OF_PROTEINS

ADAMTS20 NOTCH1 NOTCH2

9.33e-0468403M27303
PathwayWP_NOTCH1_REGULATION_OF_ENDOTHELIAL_CELL_CALCIFICATION

DLL4 NOTCH1

1.04e-0317402M39389
PathwayREACTOME_PRE_NOTCH_PROCESSING_IN_GOLGI

NOTCH1 NOTCH2

1.17e-0318402M614
PathwayREACTOME_NOTCH4_INTRACELLULAR_DOMAIN_REGULATES_TRANSCRIPTION

NOTCH1 NOTCH2

1.44e-0320402M27881
PathwayREACTOME_REGULATION_OF_FZD_BY_UBIQUITINATION

FZD5 LRP5

1.44e-0320402MM15155
PathwayREACTOME_REGULATION_OF_FZD_BY_UBIQUITINATION

FZD5 LRP5

1.59e-0321402M27401
PathwayREACTOME_SIGNALING_BY_NOTCH4

DLL4 NOTCH1 NOTCH2

1.60e-0382403M594
PathwayWP_DELTANOTCH_SIGNALING_PATHWAY

DLL4 NOTCH1 NOTCH2

1.60e-0382403MM15922
PathwayREACTOME_NOTCH2_ACTIVATION_AND_TRANSMISSION_OF_SIGNAL_TO_THE_NUCLEUS

DLL4 NOTCH2

1.75e-0322402M27210
PathwayKEGG_DORSO_VENTRAL_AXIS_FORMATION

NOTCH1 NOTCH2

2.08e-0324402M11190
PathwayREACTOME_TNFS_BIND_THEIR_PHYSIOLOGICAL_RECEPTORS

TNFRSF25 EDAR

2.44e-0326402MM15270
PathwayPID_WNT_SIGNALING_PATHWAY

FZD5 LRP5

2.83e-0328402M77
PathwayREACTOME_NOTCH_HLH_TRANSCRIPTION_PATHWAY

NOTCH1 NOTCH2

2.83e-0328402M6177
PathwayWP_CANCER_PATHWAYS

DLL4 FZD5 LAMA2 LRP5 NOTCH1 NOTCH2

2.85e-03507406M48302
PathwayREACTOME_EGR2_AND_SOX10_MEDIATED_INITIATION_OF_SCHWANN_CELL_MYELINATION

GJB1 LAMA2

3.04e-0329402M29808
PathwayREACTOME_TNFS_BIND_THEIR_PHYSIOLOGICAL_RECEPTORS

TNFRSF25 EDAR

3.04e-0329402M27555
PathwayREACTOME_ACTIVATED_NOTCH1_TRANSMITS_SIGNAL_TO_THE_NUCLEUS

DLL4 NOTCH1

3.47e-0331402M592
PathwayREACTOME_DISASSEMBLY_OF_THE_DESTRUCTION_COMPLEX_AND_RECRUITMENT_OF_AXIN_TO_THE_MEMBRANE

FZD5 LRP5

3.47e-0331402M27400
PathwayREACTOME_DISASSEMBLY_OF_THE_DESTRUCTION_COMPLEX_AND_RECRUITMENT_OF_AXIN_TO_THE_MEMBRANE

FZD5 LRP5

3.47e-0331402MM15154
PathwayREACTOME_GAP_JUNCTION_ASSEMBLY

GJB1 GJB4

3.69e-0332402MM14730
PathwayWP_HAIR_FOLLICLE_DEVELOPMENT_ORGANOGENESIS_STAGE_2_OF_3

EDAR LRP5

3.69e-0332402M40041
PathwayREACTOME_SIGNALING_BY_NOTCH2

DLL4 NOTCH2

3.92e-0333402M604
PathwayREACTOME_SIGNALING_BY_WNT_IN_CANCER

FZD5 LRP5

4.16e-0334402M27405
PathwayWP_OSX_AND_MIRNAS_IN_TOOTH_DEVELOPMENT

NOTCH1 NOTCH2

4.16e-0334402M39390
Pubmed

Helicobacter pylori Infection of Gastric Epithelial Cells Affects NOTCH Pathway In Vitro.

DLL4 NOTCH1 NOTCH2

2.63e-09349327073072
Pubmed

O-Fucose and Fringe-modified NOTCH1 extracellular domain fragments as decoys to release niche-lodged hematopoietic progenitor cells.

DLL4 NOTCH1 NOTCH2

2.63e-09349333351914
Pubmed

Canonical Notch ligands and Fringes have distinct effects on NOTCH1 and NOTCH2.

DLL4 NOTCH1 NOTCH2

1.05e-08449332820046
Pubmed

Disrupted Slit-Robo signalling results in membranous ventricular septum defects and bicuspid aortic valves.

DLL4 SLIT3 NOTCH1 NOTCH2

1.33e-081949425691540
Pubmed

Intraovarian regulation of gonadotropin-dependent folliculogenesis depends on notch receptor signaling pathways not involving Delta-like ligand 4 (Dll4).

DLL4 NOTCH1 NOTCH2

2.62e-08549323675950
Pubmed

Notch signaling mediated by Delta-like ligands 1 and 4 controls the pathogenesis of chronic GVHD in mice.

DLL4 NOTCH1 NOTCH2

2.62e-08549330181175
Pubmed

Two distinct Notch signals, Delta-like 4/Notch1 and Jagged-1/Notch2, antagonistically regulate chemical hepatocarcinogenesis in mice.

DLL4 NOTCH1 NOTCH2

2.62e-08549335064244
Pubmed

GCNT1-Mediated O-Glycosylation of the Sialomucin CD43 Is a Sensitive Indicator of Notch Signaling in Activated T Cells.

DLL4 NOTCH1 NOTCH2

9.16e-08749332060138
Pubmed

Regulation of monocyte cell fate by blood vessels mediated by Notch signalling.

DLL4 NOTCH1 NOTCH2

9.16e-08749327576369
Pubmed

The ectodomains determine ligand function in vivo and selectivity of DLL1 and DLL4 toward NOTCH1 and NOTCH2 in vitro.

DLL4 NOTCH1 NOTCH2

9.16e-08749330289388
Pubmed

Notch1 signals through Jagged2 to regulate apoptosis in the apical ectodermal ridge of the developing limb bud.

DLL4 NOTCH1 NOTCH2

2.19e-07949316245338
Pubmed

Spatiotemporal expression of Notch receptors and ligands in developing mouse placenta.

DLL4 NOTCH1 NOTCH2

3.13e-071049323665443
Pubmed

Dynamics of Notch pathway expression during mouse testis post-natal development and along the spermatogenic cycle.

DLL4 NOTCH1 NOTCH2

3.13e-071049324015274
Pubmed

Developmental expression of the Notch signaling pathway genes during mouse preimplantation development.

DLL4 NOTCH1 NOTCH2

5.73e-071249315465494
Pubmed

Vascular expression of Notch pathway receptors and ligands is restricted to arterial vessels.

DLL4 NOTCH1 NOTCH2

7.44e-071349311578869
Pubmed

Brg1 plays an essential role in development and homeostasis of the duodenum through regulation of Notch signaling.

DLL4 FZD5 NOTCH1 NOTCH2

7.63e-075049427510977
Pubmed

Endothelial Jarid2/Jumonji is required for normal cardiac development and proper Notch1 expression.

ERBB4 DLL4 NOTCH1

9.46e-071449321402699
Pubmed

Math1 controls cerebellar granule cell differentiation by regulating multiple components of the Notch signaling pathway.

DLL4 NOTCH1 NOTCH2

9.46e-071449314757642
Pubmed

Expression of Notch pathway genes in the embryonic mouse metanephros suggests a role in proximal tubule development.

DLL4 NOTCH1 NOTCH2

1.18e-061549312971992
Pubmed

Expression of Notch pathway components in fetal and adult mouse small intestine.

DLL4 NOTCH1 NOTCH2

1.45e-061649312617809
Pubmed

An essential role for Notch in neural crest during cardiovascular development and smooth muscle differentiation.

DLL4 NOTCH1 NOTCH2

1.45e-061649317273555
Pubmed

Mesenchymal Hox6 function is required for mouse pancreatic endocrine cell differentiation.

FZD5 BMPER NOTCH1 NOTCH2

1.49e-065949426450967
Pubmed

Gamma-secretase activation of notch signaling regulates the balance of proximal and distal fates in progenitor cells of the developing lung.

DLL4 NOTCH1 NOTCH2

1.76e-061749318694942
Pubmed

Segmental expression of Notch and Hairy genes in nephrogenesis.

DLL4 NOTCH1 NOTCH2

1.76e-061749315821257
Pubmed

Unravelling differential Hes1 dynamics during axis elongation of mouse embryos through single-cell tracking.

DLL4 NOTCH1 NOTCH2

1.76e-061749339315665
Pubmed

A role for notch signaling in human corneal epithelial cell differentiation and proliferation.

NOTCH1 NOTCH2

1.94e-06249217652726
Pubmed

Notch1 and Notch2 expression in osteoblast precursors regulates femoral microarchitecture.

NOTCH1 NOTCH2

1.94e-06249224508387
Pubmed

A novel Notch ligand, Dll4, induces T-cell leukemia/lymphoma when overexpressed in mice by retroviral-mediated gene transfer.

DLL4 NOTCH1

1.94e-06249211739188
Pubmed

Clinical role of Notch signaling pathway in intraductal papillary mucinous neoplasm of the pancreas.

NOTCH1 NOTCH2

1.94e-06249225041344
Pubmed

Notch controls generation and function of human effector CD8+ T cells.

NOTCH1 NOTCH2

1.94e-06249223380742
Pubmed

p73α1, a p73 C-terminal isoform, regulates tumor suppression and the inflammatory response via Notch1.

NOTCH1 TP73

1.94e-06249235617425
Pubmed

Endothelium and NOTCH specify and amplify aorta-gonad-mesonephros-derived hematopoietic stem cells.

NOTCH1 NOTCH2

1.94e-06249225866967
Pubmed

Xylosyl Extension of O-Glucose Glycans on the Extracellular Domain of NOTCH1 and NOTCH2 Regulates Notch Cell Surface Trafficking.

NOTCH1 NOTCH2

1.94e-06249232423029
Pubmed

NOTCH1 and DLL4 are involved in the human tuberculosis progression and immune response activation.

DLL4 NOTCH1

1.94e-06249232801053
Pubmed

Differential Notch1 and Notch2 expression and frequent activation of Notch signaling in gastric cancers.

NOTCH1 NOTCH2

1.94e-06249221466361
Pubmed

Notch signaling regulates formation of the three-dimensional architecture of intrahepatic bile ducts in mice.

NOTCH1 NOTCH2

1.94e-06249220069650
Pubmed

Testosterone influenced the expression of Notch1, Notch2 and Jagged1 induced by lipopolysaccharide in macrophages.

NOTCH1 NOTCH2

1.94e-06249215625786
Pubmed

Notch2 signaling is required for potent antitumor immunity in vivo.

NOTCH1 NOTCH2

1.94e-06249220351182
Pubmed

Implications of Dll4-Notch signaling activation in primary glioblastoma multiforme.

DLL4 NOTCH1

1.94e-06249223787764
Pubmed

Ongoing Dll4-Notch signaling is required for T-cell homeostasis in the adult thymus.

DLL4 NOTCH1

1.94e-06249221598246
Pubmed

A novel IgA/Delta-like 4/Notch axis induces immunosuppressive activity in human dendritic cells.

DLL4 NOTCH1

1.94e-06249227117596
Pubmed

The Notch1-Dll4 signaling pathway regulates mouse postnatal lymphatic development.

DLL4 NOTCH1

1.94e-06249221700774
Pubmed

Involvement of Notch in activation and effector functions of γδ T cells.

NOTCH1 NOTCH2

1.94e-06249224489102
Pubmed

Notch1 signaling in NOTCH1-mutated mantle cell lymphoma depends on Delta-Like ligand 4 and is a potential target for specific antibody therapy.

DLL4 NOTCH1

1.94e-06249231676012
Pubmed

Hierarchy of Notch-Delta interactions promoting T cell lineage commitment and maturation.

NOTCH1 NOTCH2

1.94e-06249217261636
Pubmed

Motch A and motch B--two mouse Notch homologues coexpressed in a wide variety of tissues.

NOTCH1 NOTCH2

1.94e-0624928440332
Pubmed

Dll4/Notch1 signalling pathway is required in collective invasion of salivary adenoid cystic carcinoma.

DLL4 NOTCH1

1.94e-06249233469672
Pubmed

The Notch pathway in podocytes plays a role in the development of glomerular disease.

NOTCH1 NOTCH2

1.94e-06249218311147
Pubmed

Recurrent mutations of NOTCH genes in follicular lymphoma identify a distinctive subset of tumours.

NOTCH1 NOTCH2

1.94e-06249225141821
Pubmed

Differential expression of Notch1 and Notch2 in developing and adult mouse brain.

NOTCH1 NOTCH2

1.94e-0624927609614
Pubmed

Notch dimerization and gene dosage are important for normal heart development, intestinal stem cell maintenance, and splenic marginal zone B-cell homeostasis during mite infestation.

NOTCH1 NOTCH2

1.94e-06249233017398
Pubmed

DLL4 regulates NOTCH signaling and growth of T acute lymphoblastic leukemia cells in NOD/SCID mice.

DLL4 NOTCH1

1.94e-06249225355291
Pubmed

Notch2 governs the rate of generation of mouse long- and short-term repopulating stem cells.

NOTCH1 NOTCH2

1.94e-06249221285514
Pubmed

Both Notch1 and Notch2 contribute to the regulation of melanocyte homeostasis.

NOTCH1 NOTCH2

1.94e-06249218353145
Pubmed

Notch signal suppresses Toll-like receptor-triggered inflammatory responses in macrophages by inhibiting extracellular signal-regulated kinase 1/2-mediated nuclear factor κB activation.

NOTCH1 NOTCH2

1.94e-06249222205705
Pubmed

Notch signaling induces cell cycle arrest in small cell lung cancer cells.

NOTCH1 NOTCH2

1.94e-06249211306509
Pubmed

Correlation of asymmetric Notch2 expression and mouse incisor rotation.

NOTCH1 NOTCH2

1.94e-06249210704869
Pubmed

Notch signaling is necessary but not sufficient for differentiation of dendritic cells.

NOTCH1 NOTCH2

1.94e-06249212907456
Pubmed

Notch1 and Notch2 receptors regulate mouse and human gastric antral epithelial cell homoeostasis.

NOTCH1 NOTCH2

1.94e-06249226933171
Pubmed

A role for Notch signaling in trophoblast endovascular invasion and in the pathogenesis of pre-eclampsia.

NOTCH1 NOTCH2

1.94e-06249221693515
Pubmed

Inflammatory cytokines induce NOTCH signaling in nucleus pulposus cells: implications in intervertebral disc degeneration.

NOTCH1 NOTCH2

1.94e-06249223589286
Pubmed

[Influence of Delta-like ligand 4/Notch signal transduction pathway upon the biological behavior of human umbilical vein endothelial cells].

DLL4 NOTCH1

1.94e-06249220193271
Pubmed

Inhibition of granulocytic differentiation by mNotch1.

NOTCH1 NOTCH2

1.94e-0624928917536
Pubmed

Functional conservation of Notch1 and Notch2 intracellular domains.

NOTCH1 NOTCH2

1.94e-06249215897231
Pubmed

Notch signalling suppresses regulatory T-cell function in murine experimental autoimmune uveitis.

NOTCH1 NOTCH2

1.94e-06249227564686
Pubmed

Probing Notch1-Dll4 signaling in regulating osteogenic differentiation of human mesenchymal stem cells using single cell nanobiosensor.

DLL4 NOTCH1

1.94e-06249235725756
Pubmed

Increased surface expression of NOTCH on memory T cells in peripheral blood from patients with asthma.

NOTCH1 NOTCH2

1.94e-06249230296524
Pubmed

Notch1 but not Notch2 is essential for generating hematopoietic stem cells from endothelial cells.

NOTCH1 NOTCH2

1.94e-06249212753746
Pubmed

Notch down-regulation in regenerated epidermis contributes to enhanced expression of interleukin-36α and suppression of keratinocyte differentiation during wound healing.

NOTCH1 NOTCH2

1.94e-06249225982147
Pubmed

Notch1-Dll4 signalling and mechanical force regulate leader cell formation during collective cell migration.

DLL4 NOTCH1

1.94e-06249225766473
Pubmed

Effects of S1 cleavage on the structure, surface export, and signaling activity of human Notch1 and Notch2.

NOTCH1 NOTCH2

1.94e-06249219701457
Pubmed

Notch signaling sustains the expression of Mcl-1 and the activity of eIF4E to promote cell survival in CLL.

NOTCH1 NOTCH2

1.94e-06249226041884
Pubmed

Whole Exome Sequencing of Lacrimal Gland Adenoid Cystic Carcinoma.

NOTCH1 NOTCH2

1.94e-06249228820917
Pubmed

Loss-of-function mutations in Notch receptors in cutaneous and lung squamous cell carcinoma.

NOTCH1 NOTCH2

1.94e-06249222006338
Pubmed

Notch1, Notch2, and Epstein-Barr virus-encoded nuclear antigen 2 signaling differentially affects proliferation and survival of Epstein-Barr virus-infected B cells.

NOTCH1 NOTCH2

1.94e-06249219339697
Pubmed

The possible correlation of Notch-1 and Notch-2 with clinical outcome and tumour clinicopathological parameters in human breast cancer.

NOTCH1 NOTCH2

1.94e-06249215492845
Pubmed

Unravelling disparate roles of NOTCH in bladder cancer.

NOTCH1 NOTCH2

1.94e-06249229643502
Pubmed

Dynamic regulation of notch 1 and notch 2 surface expression during T cell development and activation revealed by novel monoclonal antibodies.

NOTCH1 NOTCH2

1.94e-06249219915064
Pubmed

Expression levels of Notch1 and Delta-like 4 in peripheral lymphocytes and their relationship with T helper 17 (Th17) cells in renal transplant recipients.

DLL4 NOTCH1

1.94e-06249226070613
Pubmed

Programs for the persistence, vigilance and control of human CD8+ lung-resident memory T cells.

NOTCH1 NOTCH2

1.94e-06249227776108
Pubmed

Notch Inhibition Prevents Differentiation of Human Limbal Stem/Progenitor Cells in vitro.

NOTCH1 NOTCH2

1.94e-06249231316119
Pubmed

Liver-specific inactivation of Notch2, but not Notch1, compromises intrahepatic bile duct development in mice.

NOTCH1 NOTCH2

1.94e-06249218666240
Pubmed

In vivo mapping of notch pathway activity in normal and stress hematopoiesis.

NOTCH1 NOTCH2

1.94e-06249223791481
Pubmed

Dll4, a novel Notch ligand expressed in arterial endothelium.

DLL4 NOTCH1

1.94e-06249210837024
Pubmed

Developmental coronary maturation is disturbed by aberrant cardiac vascular endothelial growth factor expression and Notch signalling.

DLL4 NOTCH1 NOTCH2

2.11e-061849318093989
Pubmed

RBPjkappa-dependent Notch function regulates Gata2 and is essential for the formation of intra-embryonic hematopoietic cells.

DLL4 NOTCH1 NOTCH2

2.11e-061849315689374
Pubmed

RBPjkappa-dependent Notch signaling regulates mesenchymal progenitor cell proliferation and differentiation during skeletal development.

DLL4 NOTCH1 NOTCH2

2.51e-061949320335360
Pubmed

Notch 2 and Notch 1/3 segregate to neuronal and glial lineages of the developing olfactory epithelium.

DLL4 NOTCH1 NOTCH2

2.51e-061949316518823
Pubmed

Mutations in the NOTCH pathway regulator MIB1 cause left ventricular noncompaction cardiomyopathy.

DLL4 NOTCH1 NOTCH2

2.95e-062049323314057
Pubmed

Neurovascular EGFL7 regulates adult neurogenesis in the subventricular zone and thereby affects olfactory perception.

DLL4 NOTCH1 NOTCH2

3.43e-062149328656980
Pubmed

Endodermal Hedgehog signals modulate Notch pathway activity in the developing digestive tract mesenchyme.

DLL4 NOTCH1 NOTCH2

3.97e-062249321750033
Pubmed

Notch promotes epithelial-mesenchymal transition during cardiac development and oncogenic transformation.

DLL4 NOTCH1 NOTCH2

4.56e-062349314701881
Pubmed

Lunatic Fringe-mediated Notch signaling is required for lung alveogenesis.

DLL4 NOTCH1 NOTCH2

4.56e-062349319897741
Pubmed

ASH2L Mediates Epidermal Differentiation and Hair Follicle Morphogenesis through H3K4me3 Modification.

EDAR NOTCH1 NOTCH2

4.56e-062349338582368
Pubmed

Aberrant epidermal differentiation and disrupted ΔNp63/Notch regulatory axis in Ets1 transgenic mice.

DLL4 NOTCH1 NOTCH2

4.56e-062349324337118
Pubmed

Loss of function of the maternal membrane oestrogen receptor ERα alters expansion of trophoblast cells and impacts mouse fertility.

DLL4 NOTCH1 NOTCH2

4.56e-062349336239412
Pubmed

Loss of Gata5 in mice leads to bicuspid aortic valve.

DLL4 NOTCH1 NOTCH2

5.21e-062449321633169
Pubmed

Reduced Notch signaling leads to renal cysts and papillary microadenomas.

NOTCH1 NOTCH2

5.83e-06349220378824
Pubmed

Redundant Notch1 and Notch2 signaling is necessary for IFNγ secretion by T helper 1 cells during infection with Leishmania major.

NOTCH1 NOTCH2

5.83e-06349222396647
Pubmed

Clinicopathological analysis of ATRX, DAXX and NOTCH receptor expression in angiosarcomas.

NOTCH1 NOTCH2

5.83e-06349228796347
InteractionIGSF5 interactions

N4BP2L2 NOTCH1 NOTCH2

4.25e-0614473int:IGSF5
InteractionNTN5 interactions

LTBP1 NOTCH1 NOTCH2

2.32e-0524473int:NTN5
InteractionIGFL3 interactions

ADAM9 LRP5 NOTCH1 NOTCH2

2.80e-0575474int:IGFL3
InteractionNOTCH2 interactions

USP53 ZNF219 LTBP1 BMPER ZNF512 NOTCH1 NOTCH2

5.20e-05423477int:NOTCH2
InteractionDLL4 interactions

DLL4 NOTCH1

7.94e-056472int:DLL4
InteractionWNT10A interactions

LRP5 NOTCH1 NOTCH2

8.74e-0537473int:WNT10A
Cytoband2p22-p21

CAD LTBP1

3.11e-0584922p22-p21
GeneFamilyGap junction proteins

GJB1 GJB4

7.74e-0422342314
GeneFamilyCD molecules|Tumor necrosis factor receptor superfamily|Death inducing signaling complex

TNFRSF25 EDAR

1.35e-0329342782
CoexpressionNABA_ECM_GLYCOPROTEINS

HMCN2 CILP SLIT3 LAMA2 LTBP1 BMPER

1.49e-06191496MM17059
CoexpressionNABA_ECM_GLYCOPROTEINS

HMCN2 CILP SLIT3 LAMA2 LTBP1 BMPER

1.73e-06196496M3008
CoexpressionGAO_ESOPHAGUS_25W_C4_FGFR1HIGH_EPITHELIAL_CELLS

TARS3 HMCN2 CILP SLIT3 LAMA2 ZNF512

2.44e-06208496M39139
CoexpressionFUKUSHIMA_TNFSF11_TARGETS

DLL4 NOTCH1 NOTCH2

3.38e-0616493MM1296
CoexpressionFUKUSHIMA_TNFSF11_TARGETS

DLL4 NOTCH1 NOTCH2

3.38e-0616493M2207
CoexpressionGSE37605_TREG_VS_TCONV_C57BL6_FOXP3_IRES_GFP_UP

EDAR CILP FZD5 MAP3K21 TG

3.82e-06126495M8791
CoexpressionNABA_CORE_MATRISOME

HMCN2 CILP SLIT3 LAMA2 LTBP1 BMPER

1.09e-05270496MM17057
CoexpressionNABA_CORE_MATRISOME

HMCN2 CILP SLIT3 LAMA2 LTBP1 BMPER

1.21e-05275496M5884
CoexpressionHALLMARK_NOTCH_SIGNALING

FZD5 NOTCH1 NOTCH2

2.93e-0532493M5903
CoexpressionGSE5542_UNTREATED_VS_IFNA_TREATED_EPITHELIAL_CELLS_24H_DN

USP53 CAD EDAR NOL11 KCNMB4

3.32e-05197495M6525
CoexpressionBRUNEAU_HEART_GREAT_VESSELS_AND_VALVULOGENESIS

NOTCH1 NOTCH2

9.52e-058492M9884
CoexpressionAtlaskidney_P4_CapMesRenVes_Crym_k-means-cluster#4_top-relative-expression-ranked_500

TARS3 LTBP1 BMPER NOTCH2

5.79e-0595474gudmap_kidney_P4_CapMesRenVes_Crym_k4_500
CoexpressionAtlasDevelopingKidney_e15.5_Ureteral Smooth Musc_emap-28812_k-means-cluster#4_top-relative-expression-ranked_1000

CILP LAMA2 ADAMTS20 LTBP1 BMPER

6.96e-05195475gudmap_developingKidney_e15.5_Ureteral Smooth Musc_1000_k4
ToppCellAdult-Mesenchymal-matrix_fibroblast_2_cell-D231|Adult / Lineage, Cell type, age group and donor

HMCN2 CILP SLIT3 LAMA2 LTBP1

1.83e-06185495fb6bd7e849ecf4ed9cd9c4e2a946a2d12d62f804
ToppCellPCW_07-8.5-Mesenchymal-Mesenchymal_fibroblastic-mes_immature3_(17)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

USP53 ADAM9 SLIT3 LAMA2 BMPER

1.93e-06187495a9316e2818217ec5feae9cf8816f7249803caee6
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-Adaptive_/_Maladaptive_/_Repairing_Fibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

HMCN2 SLIT3 LAMA2 LTBP1 BMPER

1.98e-06188495ce85a56ac27a6432421dde93a1bafa8b943244b9
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

HMCN2 SLIT3 LAMA2 LTBP1 BMPER

2.09e-06190495efb757f11c2809e66ddb48a5c84f5433f111cb7c
ToppCellnucseq-Mesenchymal-Fibroblastic-Fibroblastic_2|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

USP53 SLIT3 LAMA2 LTBP1 BMPER

2.20e-0619249599ce9e3c4c50cf64ebb62145f2b5420efa0db309
ToppCelldroplet-Limb_Muscle-nan-18m-Mesenchymal|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CILP SLIT3 LAMA2 LTBP1 BMPER

2.26e-0619349549600db68ed65cafc67bd45a285b364e4f5f88af
ToppCellChildren_(3_yrs)-Mesenchymal-matrix_fibroblast_1_cell-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

USP53 SLIT3 LAMA2 LTBP1 BMPER

2.26e-06193495b3ad5ff480d99217f36cc7471e5a96a519ddb409
ToppCellfacs-GAT-Fat-3m-Mesenchymal-mesenchymal_progenitor|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CILP SLIT3 LAMA2 LTBP1 BMPER

2.37e-0619549569a29d03e664b72f32d41876510c62345c3aed31
ToppCell3'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_1-Adventitial_fibroblasts-Adventitial_fibroblasts_L.2.1.2.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

USP53 CILP SLIT3 LAMA2 LTBP1

2.37e-06195495f54bc4454270ff06e85596f98199372b50d0179f
ToppCellfacs-GAT-Fat-3m-Mesenchymal|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CILP SLIT3 LAMA2 LTBP1 BMPER

2.37e-061954951cffae2b08dbfa1c633ce24023e89b66d28b5431
ToppCellAdult-Mesenchymal-matrix_fibroblast_1_cell-D122|Adult / Lineage, Cell type, age group and donor

USP53 SLIT3 LAMA2 LTBP1 BMPER

2.37e-06195495aa0add081881d349099d12efca5cdee098038d4e
ToppCellfacs-GAT-Fat-3m-Mesenchymal-mesenchymal_stem_cell_of_adipose|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CILP SLIT3 LAMA2 LTBP1 BMPER

2.37e-061954959cef6f18664518060af7c192310dddce6d70345a
ToppCellChildren_(3_yrs)-Mesenchymal|Children_(3_yrs) / Lineage, Cell type, age group and donor

USP53 SLIT3 LAMA2 LTBP1 BMPER

2.43e-06196495bc94909f9b2dc08a59eef1914148b69720569c8f
ToppCellFibroblasts-DKK3+_Fibroblasts|World / Immune cells in Rheumatoid Arthritis Joint Synovial Tissues

HMCN2 CILP SLIT3 LAMA2 LTBP1

2.56e-061984954f4632f26a2043c5e4ab89031b4229b5dca1bd48
ToppCellBiopsy_Other_PF-Mesenchymal-Fibroblasts|Biopsy_Other_PF / Sample group, Lineage and Cell type

HMCN2 CILP SLIT3 LAMA2 LTBP1

2.69e-062004959996b6887cf2b1936e10a1aa396f09fd8da5f4c4
ToppCellParenchymal-NucSeq-Stromal-Fibroblastic|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

USP53 SLIT3 LAMA2 LTBP1 BMPER

2.69e-06200495311fab076f2ceb258e3970eb21e39344b894042a
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Myeloid-Granulocytic-Neutrophil-Neu_c1-IL1B|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

ERBB4 ABCA1 LAMA2 TG

2.81e-05159494fb9a45c1d596226128ce4f1adaebb066766e590a
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell-mesangial_typical|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

USP53 SLIT3 LAMA2 TG

2.95e-051614941b805f77790aeb8a71b08bfac2fe2eed7343258f
ToppCell368C-Fibroblasts-Fibroblast-E|368C / Donor, Lineage, Cell class and subclass (all cells)

CILP SLIT3 LAMA2 LTBP1

3.02e-05162494e17632778a57c71d6005d3abca3a0443a92040e7
ToppCell368C-Fibroblasts-Fibroblast-E-|368C / Donor, Lineage, Cell class and subclass (all cells)

CILP SLIT3 LAMA2 LTBP1

3.02e-05162494ac4a80fd72c9311ea2b3e574c6284bbce4f2756c
ToppCellAdult-Mesenchymal-chondrocyte-D231|Adult / Lineage, Cell type, age group and donor

CILP DLL4 SLIT3 LAMA2

3.17e-051644942ba57dce5f69a88f0d1e450b9780425e2d9ca7d4
ToppCell3'-Broncho-tracheal-Mesenchymal-Fibroblastic-fibroblastic_type_1-Adventitial_fibroblasts-|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

USP53 CILP LAMA2 LTBP1

3.82e-05172494e37c0b5b547a7345179ab258dd2141fec7064c17
ToppCellkidney_cells-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-Adaptive_/_Maladaptive_/_Repairing_Fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CILP LAMA2 ATP10B NOTCH2

4.00e-051744949c916af5eebd932f67dc9117e1d26ff194a2ff2c
ToppCellkidney_cells-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CILP LAMA2 ATP10B NOTCH2

4.00e-05174494bc71521f44a5fe013af42b06b5d1bd2446ecf3b5
ToppCelldroplet-Kidney-nan-18m-Epithelial-collecting_duct_principal_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EDAR SLIT3 LAMA2 ATP10B

4.18e-05176494533d544852038c0612aacf87f4b1c88ff7aace82
ToppCellfacs-Pancreas-Exocrine-18m-Mesenchymal|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CILP SLIT3 LAMA2 BMPER

4.66e-05181494269b39ac65790061d54eab47a8eeb024403f0348
ToppCellfacs-Pancreas-Exocrine-18m-Mesenchymal-pancreatic_stellate_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CILP SLIT3 LAMA2 BMPER

4.66e-05181494cd4f744b6b64ba6c22ec07afd1d3058a2546909d
ToppCellfacs-Pancreas-Exocrine-18m-Mesenchymal-pancreatic_stellate_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CILP SLIT3 LAMA2 BMPER

4.66e-05181494c8395ae872aa80b3ae1ab7c53e57b3ca15aeb0e2
ToppCellAdult-Mesenchymal-matrix_fibroblast_2_cell-D122|Adult / Lineage, Cell type, age group and donor

CILP SLIT3 LAMA2 LTBP1

4.97e-051844942b7e6f91e11c228f0521e099886867d9e998e78d
ToppCellfacs-Spleen-nan-3m-Lymphocytic-CD4-positive,_alpha-beta_T_cell|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TNFRSF25 KCNMB4 IZUMO1R NOTCH1

4.97e-05184494c37c623c4a5ff1628486d8a6461fa355ad5c264c
ToppCellCOVID-19-Endothelial_cells-Arterial_endothelial_cells|COVID-19 / group, cell type (main and fine annotations)

HMCN2 DLL4 KCNMB4 LTBP1

4.97e-051844940f19494789f38ab1a420545e15e748ca7eb345c3
ToppCellCOVID-19-Heart-Fib_2|COVID-19 / Disease (COVID-19 only), tissue and cell type

HMCN2 CILP LAMA2 LTBP1

5.07e-051854948f95d8e591bf7379d13f5a0545b0cb49e2b1ab5d
ToppCell(2)_Fibroblasts-(20)_Fibro-1|(2)_Fibroblasts / Cell class and subclass of bone marrow stroma cells in homeostatis

HMCN2 LAMA2 LTBP1 BMPER

5.18e-05186494e93415b59dd89bc8a966dab0e0b65fe215933598
ToppCellCOVID-19-Fibroblasts-Airway_smooth_muscle|COVID-19 / group, cell type (main and fine annotations)

USP53 SLIT3 LAMA2 LTBP1

5.29e-05187494464a0c3b92b778911b5f9cd73642e09e3472063a
ToppCellControl-Fibroblasts-Alveolar_FB|Control / group, cell type (main and fine annotations)

USP53 SLIT3 LAMA2 BMPER

5.29e-0518749492d468dde81125d51daf7abd4703741abe1ab91c
ToppCelldroplet-Pancreas-Exocrine-18m-Mesenchymal-pancreatic_stellate_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLIT3 LAMA2 BMPER PKHD1L1

5.29e-051874944e553721fa5598cb211f44e3226280b7e6885484
ToppCelldroplet-Pancreas-Exocrine-18m-Mesenchymal|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLIT3 LAMA2 BMPER PKHD1L1

5.29e-05187494d36e7fc6125e7a4310499365022d38f34b757a73
ToppCelldroplet-Pancreas-Exocrine-18m-Mesenchymal-pancreatic_stellate_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLIT3 LAMA2 BMPER PKHD1L1

5.29e-05187494827eae63fabf6892a82ce7779b5f395958d3d628
ToppCellControl-Fibroblasts-Other_FB|Control / group, cell type (main and fine annotations)

SLIT3 LAMA2 LTBP1 BMPER

5.29e-05187494bd3739c4a52aa1ba5deffd778e113a9800f7e158
ToppCell5'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_1-Adventitial_fibroblasts-Adventitial_fibroblasts_L.2.1.2.1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CILP SLIT3 LAMA2 LTBP1

5.51e-05189494d531399749409d614adca13d181830c6e3287508
ToppCellControl-Fibroblasts|Control / group, cell type (main and fine annotations)

USP53 SLIT3 LAMA2 LTBP1

5.63e-051904943a42a9b98d954685d38a741f44545898d0e3e9ce
ToppCelldroplet-Limb_Muscle-nan-24m-Mesenchymal-mesenchymal_stem_cell|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CILP SLIT3 LAMA2 BMPER

5.63e-05190494ad0f5605db6b694445ec9bd5dc8d2d834358c0f9
ToppCelldroplet-Fat-Gat-18m-Mesenchymal-Cd34+|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLIT3 LAMA2 LTBP1 BMPER

5.74e-051914946cab0334f76c973880bd8d1638856f2f6e4a249a
ToppCelldroplet-Fat-Gat-18m-Mesenchymal|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLIT3 LAMA2 LTBP1 BMPER

5.74e-05191494850c6fff6dc795431ef534fdaa41e4ad50f7367a
ToppCelldroplet-Fat-Gat-18m-Mesenchymal-mesenchymal_stem_cell_of_adipose|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLIT3 LAMA2 LTBP1 BMPER

5.74e-051914948b2b00202d3c98bccbae1b4a23713892fad0ff23
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-Adaptive_/_Maladaptive_/_Repairing_Fibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

USP53 SLIT3 LAMA2 LTBP1

5.74e-051914942c51850f5c559d665b8a27a12b75af9ed58dffe1
ToppCellnucseq-Mesenchymal-Fibroblastic-Fibroblastic_2-AF1|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

USP53 SLIT3 LAMA2 BMPER

5.74e-051914946688cee34beee4f151ac17fccbc9c26a9aad72e1
ToppCelldroplet-Kidney-KIDNEY-30m-Mesenchymal-fibroblast|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CILP SLIT3 LAMA2 BMPER

5.86e-05192494853a930e0641ffb50cbb4cef5837c70d75c3fc39
ToppCellPND28-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2-AF2_mature|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

HMCN2 CILP SLIT3 LAMA2

5.86e-0519249429bee88b45e23f16543ffc7cc361bc5da5d16a2b
ToppCelldroplet-Limb_Muscle-MUSCLE-30m-Mesenchymal-mesenchymal_stem_cell|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CILP SLIT3 LAMA2 BMPER

5.86e-0519249411088878043a6ff95ba1970361256a82e434b80a
ToppCellfacs-Limb_Muscle-ForelimbandHindlimb-3m-Mesenchymal-mesenchymal_stem_cell|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADAM9 SLIT3 LAMA2 BMPER

5.86e-05192494beac6b3c191b11add8e39e8d04562b478ea8929e
ToppCelldroplet-Kidney-KIDNEY-30m-Mesenchymal-Stroma____fibroblast|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CILP SLIT3 LAMA2 BMPER

5.86e-05192494d2c03490c5e835d0f0a732803093c64b8d4b4029
ToppCellChildren_(3_yrs)-Mesenchymal-matrix_fibroblast_2_cell-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

CILP SLIT3 LAMA2 LTBP1

5.86e-05192494e0f4e4470a71bfa81d9dcd8594e5f82aafc24f81
ToppCellPND28-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

HMCN2 CILP SLIT3 LAMA2

5.86e-05192494cdc652dbfabe41b324fd85c1ed933d29fb73a49f
ToppCelldroplet-Kidney-KIDNEY-30m-Mesenchymal|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CILP SLIT3 LAMA2 BMPER

5.86e-0519249449281626ecad0456fdbded2378b7028d7b589686
ToppCelldroplet-Limb_Muscle-nan-18m-Mesenchymal-nan|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLIT3 LAMA2 LTBP1 BMPER

5.86e-051924942d9e2262f1342fe17735f21f733c029d1275e955
ToppCellkidney_cells-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Degenerative_Fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

HMCN2 CILP LAMA2 LTBP1

5.98e-05193494dc8e62df6121ee99b156aca6b1b3ae555739b6f2
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

USP53 SLIT3 LAMA2 LTBP1

5.98e-0519349409a9ab029f01234459a88e3e994fe90ef4cbb8c6
ToppCellChildren_(3_yrs)-Mesenchymal-matrix_fibroblast_1_cell|Children_(3_yrs) / Lineage, Cell type, age group and donor

USP53 SLIT3 LAMA2 BMPER

5.98e-0519349499525545552b371c86b18b6ea6f4897dc6e9a9ec
ToppCellChildren_(3_yrs)-Mesenchymal-matrix_fibroblast_2_cell-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

USP53 SLIT3 LAMA2 LTBP1

5.98e-05193494261cafc167c86ab277be4ea7f08b0173e2dde26e
ToppCelldroplet-Limb_Muscle-nan-18m-Mesenchymal-mesenchymal_stem_cell|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CILP SLIT3 LAMA2 BMPER

5.98e-0519349445b5cab4dfeb0ed3b13631db5963740a792b810f
ToppCellkidney_cells-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Degenerative_Fibroblast-Degenerative_Fibroblast_119|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

HMCN2 CILP LAMA2 LTBP1

5.98e-05193494e2ee077fd381bd906e6b4329f22e7d106e422a7f
ToppCellChildren_(3_yrs)-Mesenchymal-matrix_fibroblast_1_cell-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

USP53 SLIT3 LAMA2 BMPER

6.10e-05194494e93de9428c986b8943fc169258847c650cfab0e5
ToppCellCOVID-19-Heart-Fib_2|Heart / Disease (COVID-19 only), tissue and cell type

HMCN2 CILP LAMA2 NOTCH2

6.10e-05194494d91c9f2ec47319051fc398320693fddbe8bbd4d6
ToppCell(5)_Fibroblast-C_(Myofibroblast)|World / Lung cell shreds - cell class (v4) and cell subclass (v4)

SLIT3 LAMA2 LTBP1 BMPER

6.10e-0519449429a72e565c19407bbd198cfbc2a78106fe830d05
ToppCellPCW_07-8.5-Mesenchymal-Mesenchymal_fibroblastic-mes_immature1_(0)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

ADAM9 SLIT3 LAMA2 BMPER

6.10e-05194494a3e5a15cf6c1361207f661ee15eb634f77daf1cb
ToppCellChildren_(3_yrs)-Mesenchymal-matrix_fibroblast_2_cell-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

HMCN2 SLIT3 LAMA2 LTBP1

6.22e-05195494ff0aa455e9844a6d7ae57ff59fb6cea825cf1fc2
ToppCellASK428-Mesenchymal|ASK428 / Donor, Lineage and Cell class of Lung cells from Dropseq

SLIT3 LAMA2 LTBP1 BMPER

6.22e-051954942b156163975d9a3d3fda1402acd9831d0fdc9e25
ToppCellIPF-Stromal-Fibroblast|World / Disease state, Lineage and Cell class

CILP SLIT3 LAMA2 LTBP1

6.22e-051954949c32756edb54f0c211185d9a98073fe01fd1526a
ToppCellAdult-Mesenchymal-matrix_fibroblast_1_cell|Adult / Lineage, Cell type, age group and donor

USP53 SLIT3 LAMA2 BMPER

6.22e-0519549461c9e09fc84d1012e472185d70ad0a06cee30d6e
ToppCellCOVID-19-Fibroblasts-Alveolar_FB|COVID-19 / group, cell type (main and fine annotations)

USP53 SLIT3 LAMA2 BMPER

6.22e-05195494603050beeb33c331d4b2e3fa46cae3f3e0e4bdc7
ToppCell3'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2-Peribronchial_fibroblasts|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CILP SLIT3 LAMA2 LTBP1

6.22e-051954941236dc60288c7dd91868e86e9174a2dacd3b11b3
ToppCellASK428-Mesenchymal-Fibroblast|ASK428 / Donor, Lineage and Cell class of Lung cells from Dropseq

SLIT3 LAMA2 LTBP1 BMPER

6.22e-05195494c269c0d894a0f55da6495b59d4b9abb9f68df684
ToppCellPCW_05-06-Mesenchymal|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

SLIT3 LAMA2 BMPER NOTCH2

6.35e-05196494dca52c57ba35d9395cdbca8b881f12ece721b10f
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

HMCN2 SLIT3 LAMA2 LTBP1

6.35e-051964941522958a92e0126326a9f0d9fb1c5b5c50b001ea
ToppCellIPF-Stromal-Fibroblast|IPF / Disease state, Lineage and Cell class

CILP SLIT3 LAMA2 LTBP1

6.35e-05196494f7ae604ba32b322d86d68b2b54892e7c6ab06c49
ToppCellFibroblasts-DKK3+_Fibroblasts|Fibroblasts / Immune cells in Rheumatoid Arthritis Joint Synovial Tissues

HMCN2 CILP SLIT3 LAMA2

6.35e-0519649424d64b67aa9b0e8215ad06f9101c1314b3483620
ToppCellControl-Stromal-Fibroblast|Control / Disease state, Lineage and Cell class

CILP SLIT3 LAMA2 LTBP1

6.35e-051964947ca94477498a84cafcdd9933ee92a6cbde76c70e
ToppCellControl-Stromal-Fibroblast|World / Disease state, Lineage and Cell class

CILP SLIT3 LAMA2 LTBP1

6.35e-051964941ec7a4daa51b3156db97e1fd6cb925ad311bb4b5
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

HMCN2 SLIT3 LAMA2 LTBP1

6.35e-051964941c8294014713684b50885e638668f2ce75f357f0
ToppCellfacs-Lung-nan|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ABCA1 SLIT3 LAMA2 LTBP1

6.35e-05196494b05f77f3990b662682ffeaf0e4c2fb190e0a6e65
ToppCellfacs-Lung-nan-3m|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ABCA1 SLIT3 LAMA2 LTBP1

6.35e-05196494787c6cd92035e0b1108c2c086c42a229016e476b
ToppCellnucseq-Mesenchymal-Fibroblastic|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

USP53 SLIT3 LAMA2 LTBP1

6.35e-051964947d8505dac15fa59935ccf592afc54b04c4c6554f
ToppCell3'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2-Alveolar_fibroblasts-Alveolar_fibroblasts_L.2.1.1.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

USP53 SLIT3 LAMA2 LTBP1

6.47e-0519749494a9603cbd3516fbcce871909693b88f20d41713
ToppCellInfluenza-Influenza_Severe-Lymphocyte-B-Plasmablast|Influenza_Severe / Disease, condition lineage and cell class

LRP5 GPRC5D PKHD1L1 TP73

6.47e-051974949108edafbf5744ed65f556bcbbf819a9b71176a9
ToppCell5'-Adult-Appendix-Mesenchymal-fibroblastic|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CILP SLIT3 LAMA2 BMPER

6.47e-05197494ab5d3ebc73bd7cfc64381d14b92878b370205186
ToppCell10x_3'_v3-tissue-resident_(10x_3'_v3)-mesenchymal-mesenchymal-mesenchymal_stem_cell|tissue-resident_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

CILP SLIT3 LAMA2 BMPER

6.47e-051974943bb92dd8a94e2be3b7fe51c9a21b241215477ac7
ToppCell10x_3'_v3-tissue-resident_(10x_3'_v3)-mesenchymal|tissue-resident_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

CILP SLIT3 LAMA2 BMPER

6.47e-0519749417344464fdcc5ba0c03959696b97c195f11e644c
ToppCell3'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_1-Adventitial_fibroblasts-Adventitial_fibroblasts_L.2.1.2.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CILP SLIT3 LAMA2 LTBP1

6.47e-05197494c747c496ac090309b7f8a3e9d840928f12c83f2f
ToppCellCOVID-19-Fibroblasts|COVID-19 / group, cell type (main and fine annotations)

USP53 SLIT3 LAMA2 LTBP1

6.47e-05197494fb847f2277609c31fffcdf49517243ce0684facf
ToppCell10x_3'_v3-tissue-resident_(10x_3'_v3)-mesenchymal-mesenchymal|tissue-resident_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

CILP SLIT3 LAMA2 BMPER

6.47e-051974945b8d0d7116b20d8e27541e88ec80c9f1f477e384
ToppCellControl-Stromal|Control / Disease state, Lineage and Cell class

CILP SLIT3 LAMA2 LTBP1

6.60e-05198494ae726b6b7f0a4107899be4d32ac256ffa0bd8d59
ToppCelltumor_Lung-Fibroblasts-COL14A1+_matrix_FBs|tumor_Lung / Location, Cell class and cell subclass

CILP SLIT3 LAMA2 LTBP1

6.60e-0519849474f2c7ef702b25a5b99e56121229e678ed992524
ToppCellnucseq-Mesenchymal|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

USP53 SLIT3 LAMA2 LTBP1

6.60e-051984948f52243ca8b9ba68a75ae411506a3a6de258eb97
ToppCellCOPD-Stromal-Fibroblast|COPD / Disease state, Lineage and Cell class

CILP SLIT3 LAMA2 LTBP1

6.60e-051984947904af61473cb20064f7a3a1e1bfe8d5913cf317
ToppCell5'-Parenchyma_lung-Mesenchymal|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CILP SLIT3 LAMA2 LTBP1

6.60e-05198494aae663c6da70b6e716edeed50cc7d3962d78e697
ToppCellMesenchymal|World / Lineage, Cell type, age group and donor

SLIT3 LAMA2 LTBP1 BMPER

6.73e-051994944bac110c2b3609f6ee5d0e3275da0824a6240270
ToppCellBronchus_Control_(B.)-Stromal-TX-Fibroblasts-3|Bronchus_Control_(B.) / Sample group, Lineage and Cell type

HMCN2 CILP LTBP1 BMPER

6.73e-0519949407b8c33342c62afd9c63ec2d757cfa3ba65d2a98
ToppCellnucseq-Mesenchymal-Fibroblastic-Fibroblastic_1|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

CILP SLIT3 LAMA2 LTBP1

6.73e-05199494f835e7ffe976843b0edbf695762d463da85793f3
ToppCell5'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_1-Adventitial_fibroblasts|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CILP SLIT3 LAMA2 LTBP1

6.73e-051994944e128c705ad36fd840582848f278770f356fcc8b
DrugHyoscyamine (L) [101-31-5]; Up 200; 13.8uM; HL60; HG-U133A

TNFRSF25 ABCA1 EDAR CILP ATP10B NOTCH1

3.74e-061994861424_UP
Diseaselung small cell carcinoma (biomarker_via_orthology)

DLL4 NOTCH1

2.70e-062492DOID:5409 (biomarker_via_orthology)
Diseaselung large cell carcinoma (biomarker_via_orthology)

DLL4 NOTCH1

2.70e-062492DOID:4556 (biomarker_via_orthology)
Diseaselung adenocarcinoma (biomarker_via_orthology)

DLL4 NOTCH1

1.62e-054492DOID:3910 (biomarker_via_orthology)
Diseaseintestinal cancer (implicated_via_orthology)

ERBB4 NOTCH1 NOTCH2

2.06e-0532493DOID:10155 (implicated_via_orthology)
DiseaseAdams Oliver syndrome

DLL4 NOTCH1

4.04e-056492C0265268
DiseaseAdams-Oliver syndrome 1

DLL4 NOTCH1

4.04e-056492C4551482
DiseaseCongenital defect of skull and scalp

DLL4 NOTCH1

4.04e-056492C2931779
DiseaseAdams-Oliver syndrome (is_implicated_in)

DLL4 NOTCH1

4.04e-056492DOID:0060227 (is_implicated_in)
DiseaseNeoplasm of uncertain or unknown behavior of breast

ERBB4 NOTCH1 NOTCH2

4.39e-0541493C0496956
DiseaseBreast adenocarcinoma

ERBB4 NOTCH1 NOTCH2

4.39e-0541493C0858252
Diseasearabinose measurement

ERBB4 ABCA1

5.64e-057492EFO_0021030
Diseaseadenocarcinoma (implicated_via_orthology)

NOTCH1 NOTCH2

5.64e-057492DOID:299 (implicated_via_orthology)
Diseasecentral nervous system cancer (implicated_via_orthology)

NOTCH1 NOTCH2

5.64e-057492DOID:3620 (implicated_via_orthology)
Diseasepantothenate measurement

ABCA1 CAD

7.52e-058492EFO_0021034
Diseasehemangiopericytoma (is_marker_for)

DLL4 NOTCH1

9.65e-059492DOID:264 (is_marker_for)
Diseaseurate measurement, spine bone mineral density

KCNMB4 LTBP1 SLC27A5

1.25e-0458493EFO_0004531, EFO_0007701
DiseaseMalignant neoplasm of skin

ERBB4 NOTCH1 NOTCH2

1.31e-0459493C0007114
DiseaseSkin Neoplasms

ERBB4 NOTCH1 NOTCH2

1.31e-0459493C0037286
Diseaseretinopathy of prematurity (biomarker_via_orthology)

DLL4 NOTCH1

1.76e-0412492DOID:13025 (biomarker_via_orthology)
DiseaseBreast Carcinoma

ERBB4 DLL4 MAP2K7 NOTCH1 NOTCH2 TP73

2.57e-04538496C0678222
DiseaseNeoplasm of uncertain or unknown behavior of bladder

NOTCH1 NOTCH2

2.80e-0415492C0496930
DiseaseBenign neoplasm of bladder

NOTCH1 NOTCH2

2.80e-0415492C0154017
DiseaseCarcinoma in situ of bladder

NOTCH1 NOTCH2

2.80e-0415492C0154091
Diseaseextrahepatic cholestasis (biomarker_via_orthology)

GJB1 ABCA1

3.62e-0417492DOID:13619 (biomarker_via_orthology)
DiseaseCarcinoma of bladder

NOTCH1 NOTCH2

4.06e-0418492C0699885
DiseaseSchizophrenia

ERBB4 ABCA1 HPS4 SLIT3 ADNP2 LAMA2 MAP2K7

6.03e-04883497C0036341
DiseaseCerebral Astrocytoma

NOTCH1 NOTCH2

7.91e-0425492C0750935
DiseaseIntracranial Astrocytoma

NOTCH1 NOTCH2

7.91e-0425492C0750936
DiseasePilocytic Astrocytoma

NOTCH1 NOTCH2

7.91e-0425492C0334583
DiseaseAstrocytoma

NOTCH1 NOTCH2

7.91e-0425492C0004114
DiseaseJuvenile Pilocytic Astrocytoma

NOTCH1 NOTCH2

7.91e-0425492C0280783
DiseaseDiffuse Astrocytoma

NOTCH1 NOTCH2

7.91e-0425492C0280785
DiseaseGrade I Astrocytoma

NOTCH1 NOTCH2

7.91e-0425492C1704230
DiseaseSubependymal Giant Cell Astrocytoma

NOTCH1 NOTCH2

7.91e-0425492C0205768
DiseaseMixed oligoastrocytoma

NOTCH1 NOTCH2

7.91e-0425492C0547065
DiseaseChildhood Cerebral Astrocytoma

NOTCH1 NOTCH2

7.91e-0425492C0338070
Diseasebrain cancer (implicated_via_orthology)

NOTCH1 NOTCH2

8.56e-0426492DOID:1319 (implicated_via_orthology)
DiseaseGemistocytic astrocytoma

NOTCH1 NOTCH2

8.56e-0426492C0334581
DiseaseProtoplasmic astrocytoma

NOTCH1 NOTCH2

8.56e-0426492C0334580
DiseaseFibrillary Astrocytoma

NOTCH1 NOTCH2

8.56e-0426492C0334582
DiseaseAnaplastic astrocytoma

NOTCH1 NOTCH2

9.23e-0427492C0334579
DiseaseLung Neoplasms

GJB1 MAP2K7 NOTCH2 TP73

9.81e-04265494C0024121
DiseaseMalignant neoplasm of lung

GJB1 MAP2K7 NOTCH2 TP73

9.95e-04266494C0242379
Diseasecancer (implicated_via_orthology)

DLL4 NOTCH1 NOTCH2 TP73

1.02e-03268494DOID:162 (implicated_via_orthology)
Diseasecolorectal cancer (implicated_via_orthology)

NOTCH1 NOTCH2

1.14e-0330492DOID:9256 (implicated_via_orthology)
DiseaseSquamous cell carcinoma of lung

ERBB4 NOTCH1

1.30e-0332492C0149782
Diseasecervical cancer

NOTCH1 NOTCH2

1.46e-0334492C4048328
DiseaseUterine Cervical Neoplasm

NOTCH1 NOTCH2

1.55e-0335492C0007873
DiseaseBladder Neoplasm

LAMA2 NOTCH1 NOTCH2

1.64e-03140493C0005695

Protein segments in the cluster

PeptideGeneStartEntry
VGNCTNIVYPPCDVQ

ALG11

271

Q2TAA5
GACVTQCPQTFVYNP

ERBB4

256

Q15303
NSRCYQPEPFACGIE

FBXO34

171

Q9NWN3
QGIICNANNPCFRYP

ABCA1

71

O95477
NQGANYACECPPNFT

DLL4

381

Q9NR61
LYNATCVICNSPTNP

ATP10B

1271

O94823
ECPVVPSSQVYQCIN

ADAMTS20

1636

P59510
CPVCNELFPSNVYQV

ADNP2

696

Q6IQ32
TCPAVCNFQTGEYVV

NOL11

66

Q9H8H0
DTNPLNGQYICTCPQ

NOTCH2

391

Q04721
TCPQGYTGPNCQNLV

NOTCH1

1046

P46531
IQAICFYECSPNLGP

IZUMO1R

91

A6ND01
FNTRGSYQCVDTPCP

HMCN2

4921

Q8NDA2
YYNQTTGLCQECPPC

EDAR

36

Q9UNE0
CCNPIQETYFQQLAP

HPS4

661

Q9NQG7
EPFYTCACPTGVQLQ

LRP5

316

O75197
APPQEAGVQCTCQHY

LBHD1

241

Q9BQE6
EQCVNSPGSYQCVPC

LTBP1

1011

Q14766
CPYIVQCFGTFITNT

MAP2K7

176

O14733
SIAAAVEVCQCPPGY

LAMA2

716

P24043
GVSPGYQTFVSCQQQ

ASIC3

256

Q9UHC3
GCPNCIEYFTSQGLQ

TP73

501

O15350
RTGQVPNCAVPCYQP

FZD5

211

Q13467
PTCPGCVFEGVQYQE

BMPER

161

Q8N8U9
QECPLQGNACPVTAY

GPRC5D

271

Q9NZD1
PPAQYFQGCLLDACQ

FCGBP

4686

Q9Y6R7
FVCNTKQPGCPNVCY

GJB4

51

Q9NTQ9
YSQCTQPCPPDTQGN

ADGRF2

116

Q8IZF7
DVPEYCNGSSQFCQP

ADAM9

481

Q13443
QFCQPDVFIQNGYPC

ADAM9

491

Q13443
FICNTLQPGCNSVCY

GJB1

51

P08034
CRGTSQYPCVQVYVN

KCNMB4

76

Q86W47
SFSPCVPQCQTQGSY

KPRP

226

Q5T749
STCFIYQPVANCQAP

KRTAP29-1

256

A8MX34
YQPVANCQAPCSTKN

KRTAP29-1

261

A8MX34
QLNAPYSCQAEGPCL

TARS3

36

A2RTX5
PSSFLQQTCGNVPYC

MAP3K21

866

Q5TCX8
QTVSTFSLPCCVPYN

RGS22

216

Q8NE09
PGPACAYVNLNICAN

IARS1

1076

P41252
PGQNCSNYTVRFLCP

CILP

126

O75339
FQVRECFGNTPNCPS

USP53

986

Q70EK8
NNYVCICPPNYTGEL

SLIT3

1016

O75094
NQPVGCSPSYRQVNC

TSSK4

176

Q6SA08
FLQQVNVYGVCVPGC

SLC27A5

576

Q9Y2P5
FVYCTGCGPQPVLHQ

VPREB1

11

P12018
VPAQCQGNCTFSYLE

PKHD1L1

1731

Q86WI1
QVSQCVSSSPFYCQP

TNFRSF25

126

Q93038
QFCQTVGYPCVVRPS

CAD

1076

P27708
PCQTQTYVKCPAPCQ

XP32

61

Q5T750
IKSPAPCQTQTCYVQ

XP32

121

Q5T750
PCQTQTCYVQGASPC

XP32

126

Q5T750
YQEQAGSLACVPCPV

TG

1481

P01266
IQCPNQGCEAVYSSV

ZNF512

406

Q96ME7
PPEFRCQVCGQSFTQ

ZNF219

271

Q9P2Y4
YPCNGQVIPTFCDTS

N4BP2L2

246

Q92802