Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionaspartic-type endopeptidase activity

ERVK-6 ERVK-7 ERVK-21 ERVK-9 ERVK-10 ERVK-8 ERVK-19 ERVK-25 ERVK-24

2.55e-12371369GO:0004190
GeneOntologyMolecularFunctionaspartic-type peptidase activity

ERVK-6 ERVK-7 ERVK-21 ERVK-9 ERVK-10 ERVK-8 ERVK-19 ERVK-25 ERVK-24

3.33e-12381369GO:0070001
GeneOntologyMolecularFunctionRNA-directed DNA polymerase activity

ERVK-6 ERVK-7 ERVK-10 ERVK-8 POLQ

2.59e-08141365GO:0003964
GeneOntologyMolecularFunctionRNA stem-loop binding

ERVK-6 EPRS1 ERVK-7 ERVK-10 ERVK-8

2.54e-07211365GO:0035613
GeneOntologyMolecularFunctionRNA-DNA hybrid ribonuclease activity

ERVK-6 ERVK-7 ERVK-10 ERVK-8

6.55e-07111364GO:0004523
GeneOntologyMolecularFunctionendopeptidase activity

ERVK-6 CASP14 USP9X PRSS37 ADAM29 ERVK-7 ERVK-21 ERVK-9 ERVK-10 USP20 ERVK-8 ERVK-19 ERVK-25 ERVK-24

1.46e-0643013614GO:0004175
GeneOntologyMolecularFunctionDNA polymerase activity

ERVK-6 ERVK-7 ERVK-10 ERVK-8 POLQ

5.70e-06381365GO:0034061
GeneOntologyMolecularFunctionendonuclease activity

ERVK-6 EME1 ERVK-7 ERVK-10 ERVK-8 ZC3H12C POLQ

4.09e-051361367GO:0004519
GeneOntologyMolecularFunctioncatalytic activity, acting on DNA

ERVK-6 EME1 SMARCAD1 ERVK-7 ERVK-10 METTL4 BPTF ERVK-8 POLQ

7.89e-052621369GO:0140097
GeneOntologyMolecularFunctionRNA endonuclease activity, producing 5'-phosphomonoesters

ERVK-6 ERVK-7 ERVK-10 ERVK-8

1.14e-04371364GO:0016891
GeneOntologyMolecularFunctionzinc ion binding

ERVK-6 UBR2 EPRS1 ESRRB ESRRG ERVK-7 ERVK-21 ERVK-9 ERVK-10 ESCO1 USP20 GDA THRA ERVK-8 PEX2 ERVK-19 ERVK-24

1.19e-0489113617GO:0008270
GeneOntologyMolecularFunctionpeptidase activity

ERVK-6 CASP14 USP9X PRSS37 ADAM29 ERVK-7 ERVK-21 ERVK-9 ERVK-10 USP20 ERVK-8 ERVK-19 ERVK-25 ERVK-24

1.53e-0465413614GO:0008233
GeneOntologyMolecularFunctionRNA endonuclease activity

ERVK-6 ERVK-7 ERVK-10 ERVK-8 ZC3H12C

2.05e-04791365GO:0004521
GeneOntologyMolecularFunctionendonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters

ERVK-6 ERVK-7 ERVK-10 ERVK-8

2.69e-04461364GO:0016893
GeneOntologyMolecularFunctionbeta-adrenergic receptor kinase activity

GRK2 GRK3

2.74e-0441362GO:0047696
GeneOntologyMolecularFunctiontranslation elongation factor activity

EIF5A2 EIF5AL1 EIF5A

3.24e-04201363GO:0003746
GeneOntologyMolecularFunctionG protein-coupled receptor kinase activity

GRK2 GRK3

9.46e-0471362GO:0004703
GeneOntologyMolecularFunctionclathrin light chain binding

CLTCL1 CLTC

9.46e-0471362GO:0032051
GeneOntologyMolecularFunctionATP-dependent activity

HYOU1 ACSS1 CCT4 SMARCAD1 ABCA10 ABCA9 BPTF ACSBG1 ABCC12 POLQ DNAH6 ATP2B1

1.02e-0361413612GO:0140657
GeneOntologyMolecularFunctionnuclease activity

ERVK-6 EME1 ERVK-7 ERVK-10 ERVK-8 ZC3H12C POLQ

1.05e-032311367GO:0004518
GeneOntologyMolecularFunctiontransition metal ion binding

ERVK-6 UBR2 EPRS1 ESRRB ESRRG AOX1 ERVK-7 ERVK-21 ERVK-9 ERVK-10 ESCO1 USP20 GDA THRA ERVK-8 PEX2 ERVK-19 ERVK-24

1.19e-03118913618GO:0046914
GeneOntologyMolecularFunctioncatalytic activity, acting on a nucleic acid

ERVK-6 EPRS1 EME1 FBL SMARCAD1 ERVK-7 ERVK-10 METTL4 BPTF ERVK-8 ZC3H12C POLQ

1.54e-0364513612GO:0140640
GeneOntologyBiologicalProcesspositive regulation of translational termination

EIF5A2 EIF5AL1 EIF5A

1.09e-0641353GO:0045905
GeneOntologyBiologicalProcessDNA integration

ERVK-6 ERVK-7 ERVK-10 ERVK-8

1.20e-06131354GO:0015074
GeneOntologyBiologicalProcessRNA-templated DNA biosynthetic process

ERVK-6 CCT4 ERVK-7 ERVK-10 HNRNPU ERVK-8 POLQ

1.21e-06831357GO:0006278
GeneOntologyBiologicalProcesspositive regulation of translational elongation

EIF5A2 EIF5AL1 EIF5A

2.72e-0651353GO:0045901
GeneOntologyBiologicalProcessDNA synthesis involved in DNA repair

ERVK-6 ERVK-7 ERVK-10 ERVK-8 POLQ

1.52e-05481355GO:0000731
GeneOntologyBiologicalProcesscell-cell fusion

ERVK-6 CACNA1S ERVK-21 ERVK-9 ERVK-8 ERVK-19

2.01e-05851356GO:0140253
GeneOntologyBiologicalProcesssyncytium formation by plasma membrane fusion

ERVK-6 CACNA1S ERVK-21 ERVK-9 ERVK-8 ERVK-19

2.01e-05851356GO:0000768
GeneOntologyBiologicalProcessestablishment of cell polarity

EYA1 OPHN1 FAT1 INSC PKD1 DOCK7 CORO7 EXOC4

2.20e-051771358GO:0030010
GeneOntologyBiologicalProcessregulation of translational termination

EIF5A2 EIF5AL1 EIF5A

2.24e-0591353GO:0006449
GeneOntologyBiologicalProcesssyncytium formation

ERVK-6 CACNA1S ERVK-21 ERVK-9 ERVK-8 ERVK-19

2.62e-05891356GO:0006949
GeneOntologyBiologicalProcessregulation of translational elongation

EIF5A2 EIF5AL1 EIF5A

9.47e-05141353GO:0006448
GeneOntologyBiologicalProcesstrophectodermal cellular morphogenesis

ESRRB NODAL

1.27e-0431352GO:0001831
GeneOntologyBiologicalProcesspositive regulation of protein-containing complex disassembly

EIF5A2 EIF5AL1 EIF5A PLEK

1.47e-04411354GO:0043243
GeneOntologyBiologicalProcessDNA-templated DNA replication

ERVK-6 EME1 ERVK-7 ERVK-10 METTL4 ERVK-8 POLQ

1.73e-041781357GO:0006261
GeneOntologyBiologicalProcesstranslational termination

EIF5A2 EIF5AL1 EIF5A

1.74e-04171353GO:0006415
GeneOntologyBiologicalProcessone-carbon metabolic process

MTHFD1L MAT1A AHCYL2 MTHFS

1.94e-04441354GO:0006730
GeneOntologyBiologicalProcessDNA replication

ERVK-6 EME1 ERVK-7 ERVK-10 METTL4 ESCO1 ERVK-8 CDC25A POLQ

2.18e-043121359GO:0006260
GeneOntologyBiologicalProcessestablishment or maintenance of cell polarity

EYA1 OPHN1 FAT1 INSC PKD1 DOCK7 CORO7 EXOC4

2.96e-042571358GO:0007163
GeneOntologyCellularComponentclathrin complex

CLTCL1 CLTC VPS41

2.20e-0591363GO:0071439
GeneOntologyCellularComponentmitotic spindle microtubule

HAUS7 HNRNPU CLTC

9.30e-05141363GO:1990498
DomainIF5A_HYPUSINE

EIF5A2 EIF5AL1 EIF5A

3.22e-0731293PS00302
DomainTransl_elong_IF5A_C

EIF5A2 EIF5AL1 EIF5A

3.22e-0731293IPR020189
DomainTransl_elong_IF5A

EIF5A2 EIF5AL1 EIF5A

3.22e-0731293IPR001884
DomaineIF-5a

EIF5A2 EIF5AL1 EIF5A

3.22e-0731293PF01287
DomainTrans_elong_IF5A_hypusine_site

EIF5A2 EIF5AL1 EIF5A

3.22e-0731293IPR019769
DomaineIF-5a

EIF5A2 EIF5AL1 EIF5A

3.22e-0731293SM01376
DomainCLH

CLTCL1 CLTC VPS41

3.22e-0731293SM00299
DomainClathrin

CLTCL1 CLTC VPS41

1.10e-0571293PF00637
DomainCHCR

CLTCL1 CLTC VPS41

1.10e-0571293PS50236
DomainClathrin_H-chain/VPS_repeat

CLTCL1 CLTC VPS41

1.76e-0581293IPR000547
DomainClathrin_H-chain_propeller_rpt

CLTCL1 CLTC

4.73e-0521292IPR022365
DomainClathrin-link

CLTCL1 CLTC

4.73e-0521292PF09268
Domain-

CLTCL1 CLTC

4.73e-05212922.130.10.110
DomainClathrin_heavy_chain

CLTCL1 CLTC

4.73e-0521292IPR016341
DomainClathrin_H-chain_propeller_N

CLTCL1 CLTC

4.73e-0521292IPR001473
DomainClathrin_H-chain_link/propller

CLTCL1 CLTC

4.73e-0521292IPR016025
DomainClathrin_propel

CLTCL1 CLTC

4.73e-0521292PF01394
DomainClathrin_H-chain_linker_core

CLTCL1 CLTC

4.73e-0521292IPR015348
DomainClathrin_H-chain_linker

CLTCL1 CLTC

1.41e-0431292IPR012331
DomainOest-rel_rcp

ESRRB ESRRG

1.41e-0431292IPR027289
DomainTranslation_prot_SH3-like

EIF5A2 EIF5AL1 EIF5A

2.04e-04171293IPR008991
DomainRib_L2_dom2

EIF5A2 EIF5AL1 EIF5A

2.43e-04181293IPR014722
Domain-

EIF5A2 EIF5AL1 EIF5A

2.43e-041812932.30.30.30
DomainOest_rcpt/oest-rel_rcp

ESRRB ESRRG

4.67e-0451292IPR024178
DomainGPCR_kinase

GRK2 GRK3

9.72e-0471292IPR000239
PathwayREACTOME_HYPUSINE_SYNTHESIS_FROM_EIF5A_LYSINE

EIF5A2 EIF5AL1 EIF5A

3.43e-0651003MM14823
PathwayWP_ONECARBON_METABOLISM

MTHFD1L MAT1A AHCYL2 MTHFS

4.94e-05291004M39471
PathwayWP_ONECARBON_METABOLISM

MTHFD1L MAT1A AHCYL2 MTHFS

9.39e-05341004MM15859
Pubmed

A revised nomenclature for transcribed human endogenous retroviral loci.

ERVK-6 ERVK-7 ERVK-21 ERVK-9 ERVK-10 ERVK-8 ERVK-19 ERVK-25 ERVK-24

1.50e-1094138921542922
Pubmed

Many human endogenous retrovirus K (HERV-K) proviruses are unique to humans.

ERVK-6 ERVK-7 ERVK-10 ERVK-24

2.37e-104138410469592
Pubmed

Genomewide screening for fusogenic human endogenous retrovirus envelopes identifies syncytin 2, a gene conserved on primate evolution.

ERVK-6 ERVK-21 ERVK-9 ERVK-8 ERVK-19

7.08e-1012138514557543
Pubmed

Quantitation of HERV-K env gene expression and splicing in human breast cancer.

ERVK-6 ERVK-7 ERVK-21 ERVK-19

1.18e-095138412629516
Pubmed

Expression patterns of transcribed human endogenous retrovirus HERV-K(HML-2) loci in human tissues and the need for a HERV Transcriptome Project.

ERVK-21 ERVK-9 ERVK-10 ERVK-25 ERVK-24

7.52e-0918138518664271
Pubmed

In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.

PTBP3 EPRS1 EME1 CLTCL1 HYOU1 RAPH1 REL CCT4 AHCYL2 EPB41L3 GRPEL2 HNRNPU BPTF FRA10AC1 TKT CLTC DLD SPAG17 POLQ DNAH6 ATP2B1 CUX1 LCMT1

1.28e-0814421382335575683
Pubmed

Human eIF5A2 on chromosome 3q25-q27 is a phylogenetically conserved vertebrate variant of eukaryotic translation initiation factor 5A with tissue-specific expression.

EIF5A2 EIF5AL1 EIF5A

6.11e-083138311161802
Pubmed

New K50R mutant mouse models reveal impaired hypusination of eif5a2 with alterations in cell metabolite landscape.

EIF5A2 EIF5AL1 EIF5A

6.11e-083138336848144
Pubmed

Differential expression of eIF5A-1 and eIF5A-2 in human cancer cells.

EIF5A2 EIF5AL1 EIF5A

6.11e-083138316519677
Pubmed

Human endogenous retrovirus K10: expression of Gag protein and detection of antibodies in patients with seminomas.

ERVK-6 ERVK-10 ERVK-19

2.44e-07413837983737
Pubmed

Biological Relevance and Therapeutic Potential of the Hypusine Modification System.

EIF5A2 EIF5AL1 EIF5A

6.08e-075138326037925
Pubmed

Exploring an Alternative Cysteine-Reactive Chemistry to Enable Proteome-Wide PPI Analysis by Cross-Linking Mass Spectrometry.

EPRS1 CLTCL1 FBL USP9X CCT4 EPB41L3 HNRNPU CDC123 CLTC EIF5A ALDOC

8.26e-074111381136652389
Pubmed

Loss of ER retention motif of AGR2 can impact mTORC signaling and promote cancer metastasis.

EPRS1 CLTCL1 HYOU1 EIF5A2 CCT4 PGD HNRNPU EPG5 SLC12A2 TKT CLTC EIF5A DLD SPAG17 ALDOC

8.29e-078071381530575818
Pubmed

KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.

EPRS1 HYOU1 USP9X EIF5A2 CCT4 MTHFS EPB41L3 OPHN1 HNRNPU GDA GRK2 TKT CLTC DOCK7 DLD CORO7 ALDOC DNAH6 ATP2B1 EXOC4

1.01e-0614311382037142655
Pubmed

Human endogenous retrovirus HERV-K(HML-2) proviruses with Rec protein coding capacity and transcriptional activity.

ERVK-6 ERVK-9 ERVK-19

1.21e-066138315063128
Pubmed

Oct4 links multiple epigenetic pathways to the pluripotency network.

ESRRB ESRRG CCT4 SALL4 POU5F1B HNRNPU BPTF PBRM1

1.63e-06203138822083510
Pubmed

Nanog and Oct4 associate with unique transcriptional repression complexes in embryonic stem cells.

ESRRB SALL4 POU5F1B PBRM1

2.37e-0624138418454139
Pubmed

The murine homolog of SALL4, a causative gene in Okihiro syndrome, is essential for embryonic stem cell proliferation, and cooperates with Sall1 in anorectal, heart, brain and kidney development.

SALL4 POU5F1B NODAL

3.37e-068138316790473
Pubmed

Prediction of the coding sequences of unidentified human genes. XIX. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.

RAPH1 NBPF1 DOCK7 ZC3H12C DNAH6 EXOC4

3.45e-06102138611214970
Pubmed

mTORC2 interactome and localization determine aggressiveness of high-grade glioma cells through association with gelsolin.

EPRS1 HYOU1 CASP14 CCT4 HNRNPU CLTC DLD ATP2B1 EXOC4

4.67e-06312138937120454
Pubmed

USP45 and Spindly are part of the same complex implicated in cell migration.

EPRS1 CLTCL1 USP9X CCT4 HNRNPU PBRM1 CLTC DIAPH2

4.81e-06235138830258100
Pubmed

Autophagy negatively regulates cancer cell proliferation via selectively targeting VPRBP.

EPRS1 CLTCL1 HNRNPU CLTC

6.00e-0630138422963397
Pubmed

LOXL2 Upregulates Phosphorylation of Ezrin to Promote Cytoskeletal Reorganization and Tumor Cell Invasion.

EPRS1 HYOU1 CASP14 EIF5A2 CCT4 HNRNPU TKT CLTC ALDOC

6.82e-06327138931409639
Pubmed

The human ATP-binding cassette (ABC) transporter superfamily.

ABCA10 ABCA9 ABCC12

7.19e-0610138311435397
Pubmed

Survey of human genes of retroviral origin: identification and transcriptome of the genes with coding capacity for complete envelope proteins.

ERVK-6 ERVK-21 ERVK-19

7.19e-0610138312970426
Pubmed

Identification of SUMO Binding Proteins Enriched after Covalent Photo-Cross-Linking.

EPRS1 USP9X CCT4 SMARCAD1 HNRNPU BPTF PBRM1 CLTC EIF5A

7.70e-06332138932786267
Pubmed

A Human Tyrosine Phosphatase Interactome Mapped by Proteomic Profiling.

HYOU1 MTHFD1L CCT4 EYA1 PGD ARMCX3 TKT EIF5A PEX2 DLD UPP1 CORO7 CDC25A ZNF598 ATP2B1

8.13e-069741381528675297
Pubmed

Nuclear reprogramming by interphase cytoplasm of two-cell mouse embryos.

ESRRB SALL4 POU5F1B

9.85e-0611138324670652
Pubmed

LCP1 preferentially binds clasped αMβ2 integrin and attenuates leukocyte adhesion under flow.

MTHFD1L USP9X CCT4 EIF5AL1 GRK2 TKT CLTC EIF5A ALDOC

1.02e-05344138930333137
Pubmed

Suppression of ACE2 SUMOylation protects against SARS-CoV-2 infection through TOLLIP-mediated selective autophagy.

EPRS1 CASP14 FBL MTHFD1L CCT4 EPB41L3 PGD HNRNPU TKT CLTC EIF5A ZNF598

1.02e-056411381236057605
Pubmed

Assembly of the U5 snRNP component PRPF8 is controlled by the HSP90/R2TP chaperones.

EPRS1 HYOU1 RAPH1 INTS7 FBL MTHFD1L USP9X EIF5A2 CCT4 SMARCAD1 AHCYL2 ARMCX3 HNRNPU GDA TKT CLTC EIF5A UPP1

1.33e-0514151381828515276
Pubmed

Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.

EPRS1 HYOU1 FBL MTHFD1L USP9X CCT4 SMARCAD1 EPB41L3 PGD HNRNPU PBRM1 TKT CLTC EIF5A DOCK7 DLD ALDOC ATP2B1

1.46e-0514251381830948266
Pubmed

Identifying biological pathways that underlie primordial short stature using network analysis.

EPRS1 HYOU1 CASP14 FBL USP9X CCT4 HNRNPU BPTF PBRM1 SLC12A2 GLE1 CLTC EIF5A DOCK7 ATP2B1

1.46e-0510241381524711643
Pubmed

Comparison of Human Eukaryotic Translation Initiation Factors 5A1 and 5AL1: Identification of Amino Acid Residues Important for EIF5A1 Lysine 50 Hypusination and Its Protein Stability.

EIF5AL1 EIF5A

1.56e-052138237047039
Pubmed

Expression of estrogen-related receptors in ovarian cancer and impact on survival.

ESRRB ESRRG

1.56e-052138234089362
Pubmed

Constitutive expression of c-REL in uveal melanoma patients: correlation with clinicopathological parameters and patient outcome.

MAP3K14 REL

1.56e-052138231768922
Pubmed

Polyamines and eIF5A Hypusination Modulate Mitochondrial Respiration and Macrophage Activation.

EIF5AL1 EIF5A

1.56e-052138231130465
Pubmed

The N-terminal region of eukaryotic translation initiation factor 5A signals to nuclear localization of the protein.

EIF5AL1 EIF5A

1.56e-052138217707773
Pubmed

Proteomic analysis of ubiquitin-proteasome effects: insight into the function of eukaryotic initiation factor 5A.

EIF5AL1 EIF5A

1.56e-052138212894223
Pubmed

Altered airway and cardiac responses in mice lacking G protein-coupled receptor kinase 3.

GRK2 GRK3

1.56e-052138210198406
Pubmed

G-protein coupled receptor kinase 2 and 3 expression in human detrusor cultured smooth muscle cells.

GRK2 GRK3

1.56e-052138211762794
Pubmed

Transcriptional activity of multiple copies of a subtelomerically located olfactory receptor gene that is polymorphic in number and location.

OR4F4 OR4F17

1.56e-052138211689484
Pubmed

Comparative sequencing of a multicopy subtelomeric region containing olfactory receptor genes reveals multiple interactions between non-homologous chromosomes.

OR4F4 OR4F17

1.56e-052138211689483
Pubmed

Exosomal EIF5A derived from Lewis lung carcinoma induced adipocyte wasting in cancer cachexia.

EIF5AL1 EIF5A

1.56e-052138237743008
Pubmed

Characterization of a second human clathrin heavy chain polypeptide gene (CLH-22) from chromosome 22q11.

CLTCL1 CLTC

1.56e-05213828733129
Pubmed

Cloning of GRK2 cDNA from S49 murine lymphoma cells.

GRK2 GRK3

1.56e-05213828638670
Pubmed

Dissecting the roles of GRK2 and GRK3 in μ-opioid receptor internalization and β-arrestin2 recruitment using CRISPR/Cas9-edited HEK293 cells.

GRK2 GRK3

1.56e-052138233060647
Pubmed

G protein--coupled receptor kinases.

GRK2 GRK3

1.56e-05213828035170
Pubmed

Independent roles of eIF5A and polyamines in cell proliferation.

EIF5AL1 EIF5A

1.56e-052138215377278
Pubmed

CHC22 and CHC17 clathrins have distinct biochemical properties and display differential regulation and function.

CLTCL1 CLTC

1.56e-052138229097553
Pubmed

Expression of human endogenous retrovirus type K envelope glycoprotein in insect and mammalian cells.

ERVK-6 ERVK-19

1.56e-05213829060628
Pubmed

Sequence determination and cDNA cloning of eukaryotic initiation factor 4D, the hypusine-containing protein.

EIF5AL1 EIF5A

1.56e-05213822492279
Pubmed

Evolutionary relationships within a subgroup of HERV-K-related human endogenous retroviruses.

ERVK-6 ERVK-19

1.56e-05213829460924
Pubmed

The associations of polymorphisms of TSH receptor and thyroid hormone receptor genes with L-thyroxine treatment in hypothyroid patients.

TSHR THRA

1.56e-052138225079464
Pubmed

c-Rel Regulates Inscuteable Gene Expression during Mouse Embryonic Stem Cell Differentiation.

REL INSC

1.56e-052138226694615
Pubmed

The clathrin heavy chain isoform CHC22 functions in a novel endosomal sorting step.

CLTCL1 CLTC

1.56e-052138220065094
Pubmed

Identification of two hERR2-related novel nuclear receptors utilizing bioinformatics and inverse PCR.

ESRRB ESRRG

1.56e-052138210072763
Pubmed

Targeted inhibition of eIF5Ahpu suppresses tumor growth and polarization of M2-like tumor-associated macrophages in oral cancer.

EIF5AL1 EIF5A

1.56e-052138237653021
Pubmed

An ERRbeta/gamma agonist modulates GRalpha expression, and glucocorticoid responsive gene expression in skeletal muscle cells.

ESRRB ESRRG

1.56e-052138219631715
Pubmed

Identification of a new member of the human eIF-5A gene family.

EIF5AL1 EIF5A

1.56e-05213827622067
Pubmed

Eukaryotic initiation factor 5A is a cellular target of the human immunodeficiency virus type 1 Rev activation domain mediating trans-activation.

EIF5AL1 EIF5A

1.56e-05213828253832
Pubmed

Recurrent EZH1 mutations are a second hit in autonomous thyroid adenomas.

TSHR EZH1

1.56e-052138227500488
Pubmed

Eukaryotic initiation factor 4D. Purification from human red blood cells and the sequence of amino acids around its single hypusine residue.

EIF5AL1 EIF5A

1.56e-05213823095320
Pubmed

The deubiquitylase USP9X controls ribosomal stalling.

USP9X ZNF598

1.56e-052138233507233
Pubmed

Homology modelling of the human eukaryotic initiation factor 5A (eIF-5A).

EIF5AL1 EIF5A

1.56e-052138211742107
Pubmed

The unique hypusine modification of eIF5A promotes islet beta cell inflammation and dysfunction in mice.

EIF5AL1 EIF5A

1.56e-052138220501948
Pubmed

Combined Overexpression of JARID2, PRDM14, ESRRB, and SALL4A Dramatically Improves Efficiency and Kinetics of Reprogramming to Induced Pluripotent Stem Cells.

ESRRB SALL4 POU5F1B

1.70e-0513138326523946
Pubmed

Defining the membrane proteome of NK cells.

EPRS1 CLTCL1 HYOU1 MTHFD1L USP9X PHRF1 HNRNPU GRK2 GLE1 CLTC EIF5A PEX2 PLEK CORO7 ATP2B1 EXOC4

1.70e-0511681381619946888
Pubmed

A protein interaction network for pluripotency of embryonic stem cells.

ESRRB SALL4 SMARCAD1 POU5F1B

2.14e-0541138417093407
Pubmed

The C-terminal cytoplasmic tail of hedgehog receptor Patched1 is a platform for E3 ubiquitin ligase complexes.

EPRS1 FBL GRK2 GRK3 CLTC

2.46e-0586138526885983
Pubmed

Identification of different proteins binding to Na, K-ATPase α1 in LPS-induced ARDS cell model by proteomic analysis.

EPRS1 FBL PGD TKT CLTC DLD

2.49e-05144138635681168
Pubmed

AMPK, a Regulator of Metabolism and Autophagy, Is Activated by Lysosomal Damage via a Novel Galectin-Directed Ubiquitin Signal Transduction System.

EPRS1 HYOU1 FBL MTHFD1L USP9X CCT4 HNRNPU SLC12A2 CLTC EIF5A

2.51e-054841381031995728
Pubmed

BioID-based intact cell interactome of the Kv1.3 potassium channel identifies a Kv1.3-STAT3-p53 cellular signaling pathway.

UBE2J1 EPRS1 HYOU1 DSC2 USP9X CCT4 EPB41L3 HNRNPU EIF5A DOCK7 ATP2B1 EXOC4

2.72e-057081381239231216
Pubmed

CHK2-BRCA1 tumor-suppressor axis restrains oncogenic Aurora-A kinase to ensure proper mitotic microtubule assembly.

UBR2 EPRS1 HYOU1 FBL CCT4 PGD HNRNPU BPTF TKT CLTC

2.99e-054941381026831064
Pubmed

A balanced Oct4 interactome is crucial for maintaining pluripotency.

ESRRB SALL4 POU5F1B

3.30e-0516138335171666
Pubmed

Inactivation of the microRNA-183/96/182 cluster results in syndromic retinal degeneration.

AOX1 MTHFS USP20 THRA SLC25A15 CCL15 EXOC4

3.41e-05225138723341629
Pubmed

Two-Dimensional Fractionation Method for Proteome-Wide Cross-Linking Mass Spectrometry Analysis.

PTBP3 EPRS1 CLTCL1 USP9X CCT4 HNRNPU CKM PBRM1 CLTC DLD ALDOC DNAH6 ATP2B1

3.48e-058471381335235311
Pubmed

Proteomic Analysis of the Spinophilin Interactome in Rodent Striatum Following Psychostimulant Sensitization.

CCT4 AHCYL2 EPB41L3 HNRNPU GDA CLTC DLD ALDOC ATP2B1

3.54e-05403138930562941
Pubmed

Esrrb function is required for proper primordial germ cell development in presomite stage mouse embryos.

ESRRB POU5F1B UPP1

3.99e-0517138331315026
Pubmed

The E3 ubiquitin ligase and RNA-binding protein ZNF598 orchestrates ribosome quality control of premature polyadenylated mRNAs.

EPRS1 CASP14 USP9X CCT4 TKT CLTC ZNF598 ATP2B1

4.43e-05320138828685749
Pubmed

Human NK cells express CC chemokine receptors 4 and 8 and respond to thymus and activation-regulated chemokine, macrophage-derived chemokine, and I-309.

GRK2 GRK3

4.68e-053138210754297
Pubmed

Combined inhibition of polyamine metabolism and eIF5A hypusination suppresses colorectal cancer growth through a converging effect on MYC translation.

EIF5AL1 EIF5A

4.68e-053138236893894
Pubmed

Functional equivalence of the clathrin heavy chains CHC17 and CHC22 in endocytosis and mitosis.

CLTCL1 CLTC

4.68e-053138219509056
Pubmed

The NFKB Inducing Kinase Modulates Hematopoiesis During Stress.

MAP3K14 REL

4.68e-053138226037670
Pubmed

Ectopic expression of Cux1 is associated with reduced p27 expression and increased apoptosis during late stage cyst progression upon inactivation of Pkd1 in collecting ducts.

PKD1 CUX1

4.68e-053138221465620
Pubmed

GH substitution reverses the growth phenotype but not the defective ossification in thyroid hormone receptor alpha 1-/-beta-/- mice.

TSHR THRA

4.68e-053138211572786
Pubmed

Essential role of eIF5A-1 and deoxyhypusine synthase in mouse embryonic development.

EIF5AL1 EIF5A

4.68e-053138221850436
Pubmed

Estrogen-Related Receptors Mediate the Adaptive Response of Brown Adipose Tissue to Adrenergic Stimulation.

ESRRB ESRRG

4.68e-053138229888756
Pubmed

Identification of an active reverse transcriptase enzyme encoded by a human endogenous HERV-K retrovirus.

ERVK-6 ERVK-9

4.68e-05313829971820
Pubmed

Thyroid hormone receptors control developmental maturation of the middle ear and the size of the ossicular bones.

TSHR THRA

4.68e-053138222253431
Pubmed

Cux1 promotes cell proliferation and polycystic kidney disease progression in an ADPKD mouse model.

PKD1 CUX1

4.68e-053138228701314
Pubmed

Expression and functional study of estrogen receptor-related receptors in human prostatic cells and tissues.

ESRRB ESRRG

4.68e-053138215598686
Pubmed

Identification and characterization of eukaryotic initiation factor 5A-2.

EIF5A2 EIF5A

4.68e-053138214622290
Pubmed

The role of polyamines in supporting growth of mammalian cells is mediated through their requirement for translation initiation and elongation.

EIF5AL1 EIF5A

4.68e-053138220181941
Pubmed

Evidences of a role for eukaryotic translation initiation factor 5A (eIF5A) in mouse embryogenesis and cell differentiation.

EIF5AL1 EIF5A

4.68e-053138220458750
Pubmed

Subcellular localization of the hypusine-containing eukaryotic initiation factor 5A by immunofluorescent staining and green fluorescent protein tagging.

EIF5AL1 EIF5A

4.68e-053138212210765
Pubmed

Deoxyhypusine synthase mutations alter the post-translational modification of eukaryotic initiation factor 5A resulting in impaired human and mouse neural homeostasis.

EIF5AL1 EIF5A

4.68e-053138237333770
Pubmed

Differential effects of CC chemokines on CC chemokine receptor 5 (CCR5) phosphorylation and identification of phosphorylation sites on the CCR5 carboxyl terminus.

GRK2 GRK3

4.68e-053138210085131
Pubmed

Cardiac function in mice overexpressing the beta-adrenergic receptor kinase or a beta ARK inhibitor.

GRK2 GRK3

4.68e-05313827761854
Pubmed

A novel nodal enhancer dependent on pluripotency factors and smad2/3 signaling conditions a regulatory switch during epiblast maturation.

POU5F1B NODAL

4.68e-053138224960041
InteractionRICTOR interactions

UBE2J1 EPRS1 HYOU1 CASP14 USP9X CCT4 SMARCAD1 EPB41L3 HNRNPU PBRM1 CDC123 CLTC DLD UPP1 ATP2B1 CUX1 EXOC4

5.13e-0675912617int:RICTOR
ToppCellfacs-Marrow-T-cells-3m-Hematologic|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

UBE2J1 CACNA1S HYOU1 CKM SLC25A43 INSC NODAL

1.00e-06181129757f0cc749ae8b6a3d77e2af31f9a6e4739c57049
ToppCellfacs-Marrow-T-cells-3m-Hematologic-hematopoietic_stem_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

UBE2J1 CACNA1S HYOU1 CKM SLC25A43 INSC NODAL

1.00e-061811297d01b35cc2fc57991a35be6a06cb7351fbabd9a11
ToppCellfacs-Marrow-T-cells-3m-Hematologic-Unknown_Progenitor|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

UBE2J1 CACNA1S HYOU1 CKM SLC25A43 INSC NODAL

1.08e-061831297b0b835f3b1de1bd46a47e1b805aa8994cd3a4e3e
ToppCell3'-Broncho-tracheal-Immune_Myeloid-Myeloid_macrophage|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

REL EPB41L3 STAB1 UPP1 ZC3H12C PLEK ATP2B1

1.83e-0619812973a1707318814dabdec48f91fa6bd223f5b879653
ToppCellfacs-Tongue-nan-3m-Epithelial-nan|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PTBP3 USP9X CCT4 HNRNPU PBRM1 SLC12A2 VPS41

1.89e-0619912978d50e1ee58710d896c0204937331d9f4dcd38de0
ToppCellsevere-HLA-DR-_S100A+_Monocyte|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

UBE2J1 DSC2 PGD TKT UPP1 PLEK ATP2B1

1.95e-062001297db7046741706376682d164c385c4701aebefc2e6
ToppCellsevere-Classical_Monocyte|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

UBE2J1 DSC2 PGD TKT UPP1 PLEK ATP2B1

1.95e-062001297f46689940fdea500ce2457eec412dd2c46705819
ToppCell3'-Broncho-tracheal-Immune_Myeloid-Myeloid_monocytic-non-classical_monocyte-Non-classical_monocytes-|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

KLHL10 REL STAB1 CILP2 GRK3 PLEK

3.83e-0614312967adc34d8ad11e57950a5a258ae9bf8f52259385a
ToppCelldroplet-Lung-18m-Hematologic-myeloid-non-classical_monocyte|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

MAP3K14 REL GDA GRK3 SLC12A2 PLEK

9.65e-061681296689c41f6e9f65381570991cc311cba49a57ec955
ToppCelldroplet-Lung-nan-18m-Myeloid-non-classical_monocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MAP3K14 REL GDA GRK3 SLC12A2 PLEK

9.98e-061691296ba023ee7bb165c2bfbefc2d969ff32ca1eeed33b
ToppCelldroplet-Lung-nan-18m-Myeloid-Nonclassical_Monocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MAP3K14 REL GDA GRK3 SLC12A2 PLEK

9.98e-061691296c96e0f3241d13926dbee9f91c0c8c5bfa7479a0d
ToppCellkidney_cells-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_1|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ESRRB ESRRG ABCA10 ABCA9 GSDME SLC12A2

1.14e-0517312960c74bdb40e635d906fd180412c23bf7fed61621e
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_1|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ESRRB ESRRG ABCA10 ABCA9 OPHN1 SLC12A2

1.14e-0517312964bc6d93716f093b460c8b047199db8cab5fea720
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ESRRB ESRRG ABCA10 ABCA9 OPHN1 SLC12A2

1.47e-051811296e0abf2707d9e0aa942c657eef7d2cbcd02f060dd
ToppCellAdult-Epithelial-ciliated_cell-D122|Adult / Lineage, Cell type, age group and donor

NWD1 MAT1A ESRRG EYA1 SPAG17 DNAH6

1.52e-0518212967ded554a4b441e6496db673ba206c0d76ccad7d9
ToppCellChildren_(3_yrs)-Epithelial-ciliated_cell-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

NWD1 ESRRG EYA1 CFAP20DC SPAG17 DNAH6

1.62e-0518412965daff849625f2f41d56615569c0ed59cd733b34c
ToppCellAdult-Epithelial-ciliated_cell-D175|Adult / Lineage, Cell type, age group and donor

NWD1 ESRRG EYA1 CFAP20DC SPAG17 DNAH6

1.67e-05185129630f4980dee6cd5959655f8d74049f3bfb5312611
ToppCellSmart-seq2-blood_(Smart-seq2)-myeloid-myeloid_monocytic-classical_monocyte|blood_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

TOPAZ1 REL STAB1 GRK2 DIAPH2 SPAG17

1.72e-05186129623b8d51d20b05795a73892d3e20e0f9b6a207820
ToppCell3'-Broncho-tracheal-Immune_Myeloid-Myeloid_macrophage-elicited_macrophage-Monocyte-derived_macrophage-Monocyte-derived_macrophage_L.1.2.3.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

REL EPB41L3 UPP1 ZC3H12C PLEK ATP2B1

2.00e-0519112960b296404ebad0aadb75737f8c0462ec6934fc8bb
ToppCellfacs-Brain_Non-Myeloid-Hippocampus-3m-Macroglial-astrocyte|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NWD1 ACSS1 EYA1 GRK3 ACSBG1 ALDOC

2.06e-051921296261211a86e6f63b09c2ddce1d2d9257d311f1770
ToppCellrenal_cortex_nuclei|World / Celltypes from Cells and Nuclei per compartment and clinical group

ESRRG AHCYL2 EPB41L3 SNX29 CUX1 EXOC4

2.06e-051921296e8cc4d08fcfceeab75a02558817e4ccd7dbafe3a
ToppCellTCGA-Prostate-Primary_Tumor-Prostate_Adenocarcinoma-Acinar_Adenocarcinoma-6|TCGA-Prostate / Sample_Type by Project: Shred V9

EPRS1 C2orf69 USP9X BPTF PBRM1 CLTC

2.12e-051931296abd71b2cf667ef2b1c4d88acd0c1dd19a12ff659
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Connecting_Tubule_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

RAPH1 ESRRG MAP3K14 HS3ST5 FAT1 DOCK7

2.18e-05194129646070fbb0ee0eb9e1801c43b73a15707471056dc
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

RAPH1 ESRRG MAP3K14 HS3ST5 FAT1 DOCK7

2.18e-051941296abacb6a8d7a9003f2f6c2be0305507f1c1c50347
ToppCell3'-Broncho-tracheal-Immune_Myeloid-Myeloid_monocytic-non-classical_monocyte-Non-classical_monocytes-Non-classical_monocytes_L.1.2.2.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

REL EPB41L3 GRK2 GRK3 PLEK ATP2B1

2.18e-05194129616c6fcbd36d473b883fb5361caca86eb134767ab
ToppCellMild/Remission-B_memory-0|World / disease group and sub_cluster of B and Plasma cells(res = 0.5)

REL CHPT1 NXT1 EIF5A CORO7 ATP2B1

2.24e-0519512963c51f005d8546c570752f5f0ce6b8ac242d3c54b
ToppCellRA-02._Fibroblast_II|RA / Chamber and Cluster_Paper

MTHFD1L AOX1 ABCA10 ABCA9 OPHN1 DIAPH2

2.24e-0519512966a02ebbeb3199447ddce64d92d8809436e040eba
ToppCell3'-Broncho-tracheal-Immune_Myeloid-Myeloid_macrophage-elicited_macrophage|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

REL EPB41L3 STAB1 ZC3H12C PLEK ATP2B1

2.31e-051961296c2bbb48c4aa979b03cb6f4ce9f351f492977c992
ToppCell3'-Broncho-tracheal-Immune_Myeloid-Myeloid_macrophage-elicited_macrophage-Monocyte-derived_macrophage|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

REL EPB41L3 STAB1 ZC3H12C PLEK ATP2B1

2.31e-05196129664c2abc0087bf2ae547932377f3662e3be1cc63e
ToppCellCOVID-19_Mild-Classical_Monocyte-cMono_3|COVID-19_Mild / Disease condition and Cell class

DSC2 PGD STAB1 GRK2 GRK3 TKT

2.31e-051961296f245e929a286cb097130572e1027b4f01be8b04d
ToppCell10x_3'_v2v3-Non-neoplastic-Myeloid-Mono-Mono_anti-infl-Z|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

PTBP3 DSC2 EPB41L3 STAB1 GRK2 CLTC

2.51e-051991296994e885b8d1874006302a081d13f1ee881d64612
ToppCellMacroglial-Astrocytes|Macroglial / cells hierarchy compared to all cells using T-Statistic

NWD1 ACSS1 AHCYL2 EYA1 ACSBG1 DOCK7

2.59e-052001296941536b7c32f1e63c70535233b2ccce0cd7bf96e
ToppCellSubstantia_nigra-Macroglia-ASTROCYTE|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

NWD1 CHPT1 ACSBG1 ABCC12 ALDOC

4.45e-051341295a632d78890fcc20db81d2cf6b299470706d2e182
ToppCellSubstantia_nigra-Macroglia-ASTROCYTE-Gja1|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

NWD1 CHPT1 ACSBG1 ABCC12 ALDOC

4.45e-0513412958be2db71d9d29f9a57a64efdc89cf8c3e32b363b
ToppCellPND07-Immune-Immune_Myeloid-Granulocytic-Neutrophil-Neutrophil_mature|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

PGD GDA GSDME GRK2 PLEK

5.48e-05140129590298cac4bcec614a48e60b5c139c86daa9f0321
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

CIART ESRRG EPB41L3 ABCA10 GSDME

5.48e-0514012955e81fa3a19d23f0e9cae3878431ca1f78dff7238
ToppCellPND07-Immune-Immune_Myeloid-Granulocytic-Neutrophil|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

PGD GDA GSDME GRK2 PLEK

5.48e-051401295671ab1f5cbd8568bf93ebdf961c2a1ede06d2bcb
ToppCell367C-Myeloid-Macrophage-SPP1+_Macrophage_2|367C / Donor, Lineage, Cell class and subclass (all cells)

RBM44 REL HNRNPU UPP1 PLEK

5.67e-051411295e409da87da5a38ba4d0ccc5e3f8bd89f480f9dab
ToppCellParenchymal-NucSeq-Epithelial-Epi_submucosal-gland-SMG_Serous|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

CIART ESRRG ADAM29 TECTA SLC12A2

6.06e-05143129592ddc3e3f6ba78dd9daeb272c12503ec2650a874
ToppCellCiliated_cells-A-IPF_02|World / lung cells shred on cell class, cell subclass, sample id

NWD1 EYA1 CCL15 SPAG17 DNAH6

7.85e-0515112959d03ce73af15ef40c592d19b36aff46bebc14c40
ToppCellfacs-Brain_Non-Myeloid-Hippocampus_-18m-Macroglial-astrocyte|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NWD1 AOX1 ACSBG1 ALDOC NODAL

8.61e-0515412955ed64bbf603290e6dc34f81d145982690b89dd0d
ToppCellLPS_only-Epithelial_airway-Ciliated_cells-Ciliated|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

NWD1 MAT1A TSHR SPAG17 DNAH6

8.61e-0515412959ca71d440c4f87781e6525b8141e7d8d470b6a8e
ToppCelldroplet-Fat-SCAT-30m-Myeloid|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RBM44 REL CKM GRK3 PLEK

8.61e-05154129573de626b210ec5482ba89a65e784c1e77ff2894e
ToppCelldroplet-Fat-SCAT-30m-Myeloid-myeloid_cell|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RBM44 REL CKM GRK3 PLEK

8.61e-05154129556fe9953e58f71626d3ddf63d340ed35dfc4ce9f
ToppCellLPS_only-Epithelial_airway-Ciliated_cells|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

NWD1 MAT1A TSHR SPAG17 DNAH6

8.61e-05154129558072ce422d09f2de602580325eaac6c4ec6c136
ToppCell5'-Adult-Appendix-Hematopoietic-B_cells-Cycling_B_cell|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

EME1 SNX29 CFAP20DC GRK3 PLEK

9.15e-051561295203ef22eb76bd2b829b027c30af0557080f4006c
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_2|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ESRRB ESRRG EPB41L3 ABCA10 OPHN1

9.72e-0515812957960337d87afecf2692ab65e5991f052ceddfacc
ToppCellPBMC_fresh-frozen-Mild-Moderate_progression_d02_child-Lymphocytic-Lymphocytic_B|Mild-Moderate_progression_d02_child / Compartment, severity and other cell annotations on 10x 3' data (130k)

SNX29 GRK3 CHPT1 PLEK ATP2B1

1.12e-0416312956bed27d2f67a430a847da5eb47878d14b4949c45
ToppCellCiliated_cells-B-Cryobiopsy_01|World / lung cells shred on cell class, cell subclass, sample id

NWD1 EYA1 CCL15 SPAG17 DNAH6

1.16e-0416412950e9961acbb1d6c0089e6805ba6756736fa4d8bed
ToppCelldroplet-Fat-Mat-18m-Myeloid-monocyte|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PGD GDA GSDME UPP1 PLEK

1.16e-041641295a27b9b3380f29bb17c9f787423f2591f2b9cf33e
ToppCellPND14-Immune-Immune_Myeloid-DC-maDC|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CACNA1S MAP3K14 REL GRK3 ZC3H12C

1.19e-0416512951c3709ac9f96ace1f3b28e1f2f15b4a8d65885ca
ToppCellPND14-Immune-Immune_Myeloid-DC-maDC-maDC_mature|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CACNA1S MAP3K14 REL GRK3 ZC3H12C

1.19e-041651295fbc7d97e6f30975d35c76a7c97947a34cf5975d2
ToppCelldroplet-Spleen-nan-24m-Myeloid-granulocyte|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TMEM216 PGD GDA GSDME UPP1

1.19e-0416512953cdb921f5b9facf04f81995d5641ac14ef3dbb6f
ToppCellPosterior_cortex-Neuronal-Excitatory-eN1(Slc17a7)-eN1_2-Fezf2|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

CASP14 MAT1A PROKR2 ABCC12

1.19e-04871294aaca22b97a42a1c4a10c5da708d1462101814386
ToppCelldroplet-Lung-30m-Hematologic-myeloid-non-classical_monocyte-nonclassical_monocyte_l4|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

MAP3K14 REL GRK3 SLC12A2 PLEK

1.30e-041681295d823979335ac6b5d1f062ebb741c759d2f919dbf
ToppCelldroplet-Spleen-SPLEEN-30m-Myeloid-granulocyte|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TMEM216 PGD GDA GSDME UPP1

1.30e-041681295c0ff30e2c47005514131a0866cf10a1c228128fc
ToppCelldroplet-Lung-18m-Hematologic-myeloid-non-classical_monocyte-nonclassical_monocyte_l4|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

MAP3K14 REL GRK3 SLC12A2 PLEK

1.30e-0416812954b5be7c6662eceddf90a65015f12908278d1664e
ToppCellfacs-Lung-24m-Hematologic-myeloid-non-classical_monocyte-nonclassical_monocyte_l4|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

GDA GRK2 GRK3 SLC12A2 PLEK

1.30e-041681295c0aef5947b1d7e2c81a7481c509feda1687fcd7f
ToppCellfacs-Lung-24m-Hematologic-myeloid-non-classical_monocyte|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

GDA GRK2 GRK3 SLC12A2 PLEK

1.30e-041681295c861f80aa12caf54a94d93e38539ff41dc5227a6
ToppCellImmune_cells-Neutrophils|Immune_cells / Lineage and Cell class

TMEM216 PGD GDA GSDME TKT

1.30e-0416812953539f802fe0143da1462df0618f78f9f15143f71
ToppCelldroplet-Lung-30m-Hematologic-myeloid-non-classical_monocyte|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

MAP3K14 REL GRK3 SLC12A2 PLEK

1.30e-041681295f377ff4c066a9857ad14d245e56325ad220e22e1
ToppCelldroplet-Lung-LUNG-30m-Myeloid-Nonclassical_Monocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MAP3K14 REL GRK3 SLC12A2 PLEK

1.33e-041691295411556e93adcbb7e4d79b02f3dc72963ec8a0759
ToppCelldroplet-Lung-LUNG-30m-Myeloid-non-classical_monocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MAP3K14 REL GRK3 SLC12A2 PLEK

1.33e-04169129539b1acfd099abb9de18c29c05c7a67709ea76775
ToppCelldroplet-Lung-21m-Hematologic-myeloid-non-classical_monocyte-nonclassical_monocyte_l4|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

REL GDA GRK3 SLC12A2 PLEK

1.33e-041691295b059304543876f514d5c7214f1f0a2da00f10a67
ToppCelldroplet-Lung-21m-Hematologic-myeloid-non-classical_monocyte|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

REL GDA GRK3 SLC12A2 PLEK

1.33e-041691295945f737984c4de70a4e9c214053b005358053dd5
ToppCellPBMC_fresh-frozen-Mild-Moderate_progression_d02_child-Lymphocytic-Lymphocytic_B-B_cell|Mild-Moderate_progression_d02_child / Compartment, severity and other cell annotations on 10x 3' data (130k)

SNX29 GRK3 CHPT1 PLEK ATP2B1

1.49e-041731295d56e337eae727a29cd53cfd628e1b3c0a98e1f51
ToppCelldroplet-Marrow-nan-18m-Myeloid-granulocyte|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TMEM216 PGD GSDME TKT UPP1

1.53e-0417412954b749ac9f05776c0c56b74daca833bd0b5704299
ToppCellfacs-Large_Intestine-Proximal-3m-Epithelial-nan|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PTBP3 DSC2 USP9X EPB41L3 ATP2B1

1.61e-0417612951dd54bfaa58541de51e5a8328651d390833bd480
ToppCellfacs-Lung-EPCAM-3m-Myeloid-dendritic_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CACNA1S MAP3K14 REL ZC3H12C LYPD8

1.65e-041771295d445167dae956e641386f84ab3ae9f47c089e09a
ToppCellFetal_29-31_weeks-Epithelial-ciliated_cell-D062|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

NWD1 MAT1A EYA1 SPAG17 DNAH6

1.70e-041781295de5d50d7ca9ee9eb62f50c88a0c6d47f0694b2e6
ToppCellControl-Epithelial_cells-Airway_ciliated|Control / group, cell type (main and fine annotations)

NWD1 ESRRG EYA1 SPAG17 DNAH6

1.88e-041821295fb725d10d9ed25dfc6d5bb69cfef78513f7d3e8f
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

ESRRB ESRRG ABCA10 UPP1 DNAH6

1.88e-041821295a8cc56f32efe180e8fb5d69dbe606a794b3db700
ToppCell5'-Adult-LargeIntestine-Epithelial-mature_enterocytic-Paneth|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CLYBL TKT EIF5A PEX2 DLD

1.88e-04182129542e3d32911d5d5cc14d8391623968af594cf2e5f
ToppCellkidney_cells-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_2|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ESRRG ABCA10 OPHN1 SLC12A2 DOCK7

1.93e-0418312952f0ee40e69ad1259e56e8ee4b352736900eb8901
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_2|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ESRRB ESRRG EPB41L3 OPHN1 SLC12A2

1.93e-0418312952e831a4d99c6f983793df71c0994124c943c6da9
ToppCellPND03-Immune-Immune_Myeloid-Monocytic-Macrophage-AM-AM_mature|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

PTBP3 PGD GDA TKT PLEK

1.98e-041841295fe9ea4d0e0be820e95eaf9bb42a5560d0e177574
ToppCellSmart-start-Cell-Wel_seq-Neoplastic-Differentiated-like-AC-like-AC-like-C|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

OPHN1 ACSBG1 EIF5A DPY19L2P2 EXOC4

1.98e-041841295629cfed10e1112cf30f6a828ce9efbbc6b207789
ToppCell3'-Broncho-tracheal-Immune_Myeloid-Myeloid_macrophage-elicited_macrophage-Monocyte-derived_macrophage-Monocyte-derived_macrophage_L.1.2.5.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

REL EPB41L3 STAB1 PLEK ATP2B1

1.98e-041841295d1ea2b60fb1ca1a0b809d131310c43903a9e84ce
ToppCell3'-Parenchyma_lung-Immune_Myeloid-Myeloid_macrophage-elicited_macrophage-Monocyte-derived_macrophage-Monocyte-derived_macrophage_L.1.2.3.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

REL EPB41L3 STAB1 PLEK ATP2B1

1.98e-041841295b45b1fdba13c8ed2a04a4fb3b62d8ad92785c768
ToppCelldroplet-Lung-18m-Hematologic-myeloid-classical_monocyte_proliferating-classical_monocyte_proliferating_l33-52|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

EME1 MTHFD1L CDC25A SPAG17 POLQ

2.03e-04185129547c69500877b851c0c9744f5e1ef2ee0bff99168
ToppCellCV-Moderate-7|Moderate / Virus stimulation, Condition and Cluster

UBR2 EPRS1 CLTC POLQ EXOC4

2.03e-041851295a6c9203ce6c2892a4a369c9bcfb85720f01cbb3f
ToppCellCOVID-19-Epithelial_cells-Airway_ciliated|COVID-19 / group, cell type (main and fine annotations)

NWD1 ESRRG EYA1 SPAG17 DNAH6

2.03e-04185129518a40f0a338aa398d81384b5159fb80ce8a2020c
ToppCellPrimary_Visual_cortex_(V1C)-Non-neuronal-Macroglial-Astro-Astrocyte-Astro_L1-6_FGFR3_ETNPPL|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

CACNA1S NWD1 ACSS1 EYA1 ACSBG1

2.08e-04186129573cf266aeecd3cc15e8cb6094588a393bca8fbe6
ToppCellCiliated_cells-B-IPF_01|World / lung cells shred on cell class, cell subclass, sample id

NWD1 ESRRG CCL15 SPAG17 DNAH6

2.08e-041861295f72267d533fd0c5280d9741ceee3dd116300a7e4
ToppCellCV-Moderate-7|CV / Virus stimulation, Condition and Cluster

UBR2 EPRS1 CLTC POLQ EXOC4

2.08e-0418612958571956890fc9894d766ba294a28e376b4aba428
ToppCellPND03-Immune-Immune_Myeloid-Monocytic-Macrophage-AM|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

PTBP3 PGD GDA TKT PLEK

2.08e-0418612957950e03ea080238c168b9d807e217f459acdfb28
ToppCellfacs-Brain_Non-Myeloid-Striatum-3m-Macroglial-astrocyte|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NWD1 ACSS1 GRK3 ACSBG1 ALDOC

2.08e-041861295ac7a84b11b4550c4ac01eab370dc8ab88e4fb72b
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

ESRRB ESRRG ABCA10 ABCA9 UPP1

2.13e-04187129577886f99c229610abd28c4c370d2c7d1536c9782
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_1|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

ESRRB ESRRG EYA1 ABCA10 ABCA9

2.13e-041871295f124d2c699b717b7c02a1a70493f515b83dc2f4c
ToppCellEpithelial-ciliated_cell|World / Lineage, Cell type, age group and donor

NWD1 ESRRG EYA1 SPAG17 DNAH6

2.19e-04188129561a459f3fe57e5728efc72637ff2edc2d343492b
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_1|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ESRRB ESRRG ABCA10 OPHN1 GSDME

2.19e-041881295bc089cd73d283ed7d2ecbb3936673b4edc89f666
ToppCellCOVID-19-kidney-DCT|kidney / Disease (COVID-19 only), tissue and cell type

ACSS1 ESRRB ESRRG ABCA10 ABCA9

2.19e-041881295df1fd0819d301679f3c9ea404e942e39095912eb
ToppCellAdult-Epithelial-ciliated_cell-D231|Adult / Lineage, Cell type, age group and donor

NWD1 ESRRG EYA1 SPAG17 DNAH6

2.19e-04188129534b11f72ca73153d02edcd09b38983ad1a504659
ToppCellChildren_(3_yrs)-Epithelial-ciliated_cell|Children_(3_yrs) / Lineage, Cell type, age group and donor

NWD1 ESRRG EYA1 SPAG17 DNAH6

2.19e-0418812952b6dfc88be9ded7b88da9fe78a9cd9f9b3af8af3
ToppCellfacs-Brain_Myeloid-Striatum-3m-Myeloid-nan|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HYOU1 ABCA9 STAB1 CLTC PLEK

2.24e-0418912956dd4ec5ce4beb856f0d2d1654e3c4676d1d63736
ToppCellRA-14._Fibroblast_III|RA / Chamber and Cluster_Paper

MTHFD1L REL EPB41L3 FAT1 SLC9B2

2.24e-04189129546e9a58aacd79db5a02898a8c7244e1884adcfd1
ToppCellChildren_(3_yrs)-Epithelial-ciliated_cell-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

NWD1 ESRRG EYA1 SPAG17 DNAH6

2.24e-04189129568a3cf7763d6f9b95d6d6524eff7a16042703f1d
ToppCellRA-14._Fibroblast_III|World / Chamber and Cluster_Paper

MTHFD1L REL EPB41L3 FAT1 SLC9B2

2.24e-041891295b6e12d24d2b0735730bdc625f8318c1c9c2a9b3b
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

ESRRB ESRRG EYA1 ABCA10 ABCA9

2.24e-041891295e32172ad09e93f6ac6ea2b92145b2b73003f7970
ToppCellfacs-Brain_Myeloid-Striatum-3m-Myeloid|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HYOU1 ABCA9 STAB1 CLTC PLEK

2.24e-0418912953ae479ec7e00c57127cbe51a398329b10ca9848c
DrugET-18-OCH3

CLTCL1 ESRRB ESRRG GSDME ACSBG1 CLTC PEX2 PLEK

4.74e-071201318CID000001392
Drugketononestrol aziridine

ESRRB ESRRG GSDME TKT

7.19e-07131314CID000130642
Drug2-phenylindole

ESRRB ESRRG GSDME TKT

7.19e-07131314CID000013698
Drugexemestane

ESRRB ESRRG FAT1 GSDME ACSBG1

4.72e-06431315CID000060198
DrugCEDO

MAP3K14 AOX1 DIAPH2

6.41e-0671313CID000130738
Druggluconate

ERVK-6 CLTCL1 ESRRB ESRRG PGD GSDME ACSBG1 TKT CLTC ALDOC

6.53e-0628713110CID000000604
Drugtamoxifen aziridine

ESRRB ESRRG GSDME TKT

7.07e-06221314CID003033894
DrugU23,469

ESRRB ESRRG GSDME

1.52e-0591313CID000161922
Drugsodium molybdate

ESRRB ESRRG AOX1 CCT4 GSDME

1.92e-05571315CID000061424
DrugNSC406942

CACNA1S CLTCL1 FBL ESRRB ESRRG GSDME PBRM1 GRK2 CLTC EIF5A CORO7 ALDOC ATP2B1

2.37e-0556513113CID000001115
Drugcarbodiimide

MAT1A AOX1 TSHR MTHFS GRK2 GRK3 SLC12A2

2.76e-051511317CID000009864
DrugBadg

CLTCL1 CLTC

3.29e-0521312CID000125951
DrugN'-((1E)-(4-(diethylamino)phenyl)methylene)-4-hydroxybenzohydrazide

ESRRB ESRRG

3.29e-0521312ctd:C501618
DrugPacMI

ERVK-6 DLD

3.29e-0521312CID000098723
Drugraloxifene

ESRRB ESRRG AOX1 HNRNPU CKM GSDME THRA ACSBG1 EIF5A NODAL

3.69e-0535113110CID000005035
DrugAC1L1K7W

ESRRB ESRRG GSDME ACSBG1

4.25e-05341314CID000005377
Drugcentchroman

ESRRB ESRRG CCT4 GSDME

4.25e-05341314CID000035805
Drugpentofuranose

ERVK-6 PTBP3 EPRS1 FBL AHCYL2 TKT UPP1 ALDOC

4.32e-052211318CID000000993
Drug1H-1,2,4-triazole-3-carboxamide

MAP3K14 AHCYL2 UPP1

5.10e-05131313CID000065125
Drugtyrphostin 23

CLTCL1 HNRNPU GRK2 GRK3 CLTC PLEK

5.72e-051161316CID000002052
DrugAC1NR9P8

CLTCL1 GRK2 GRK3 CLTC

6.64e-05381314CID005287445
Diseasehearing impairment

ESRRB SALL4 EYA1 TECTA GSDME

5.34e-05981215C1384666
DiseaseGeneralized Thyroid Hormone Resistance

TSHR THRA

9.95e-0541212C4722330
Diseaseunipolar depression

ESRRG GRIK3 EYA1 METTL4 SNX29 BPTF EIF5AL1 FAT1 GSDME TKT PKD1 EIF5A VPS41 DLD DNAH6

1.27e-04120612115EFO_0003761
DiseaseBlastocyst Disintegration

GRK2 LCMT1

3.46e-0471212C0012684
DiseaseEmbryo Loss

GRK2 LCMT1

3.46e-0471212C0752351
DiseaseEmbryo Death

GRK2 LCMT1

3.46e-0471212C0752350
DiseaseEmbryo Resorption

GRK2 LCMT1

3.46e-0471212C0013937
DiseaseOROFACIODIGITAL SYNDROME VI

TCTN3 TMEM216

3.46e-0471212C2745997
DiseaseEmbryo Disintegration

GRK2 LCMT1

3.46e-0471212C1136082
Diseaseinter-alpha-trypsin inhibitor heavy chain h4 measurement

STAB1 TKT

3.46e-0471212EFO_0020481
DiseaseHereditary hearing loss and deafness

ESRRB EYA1 TECTA GSDME DLD

3.47e-041461215cv:C0236038
DiseaseCarcinomatosis

TSHR GDA SLC12A2 TKT EIF5A

5.74e-041631215C0205699
DiseaseCarcinoma, Spindle-Cell

TSHR GDA SLC12A2 TKT EIF5A

5.74e-041631215C0205697
DiseaseUndifferentiated carcinoma

TSHR GDA SLC12A2 TKT EIF5A

5.74e-041631215C0205698
DiseaseAnaplastic carcinoma

TSHR GDA SLC12A2 TKT EIF5A

5.74e-041631215C0205696
DiseaseCarcinoma

TSHR GDA SLC12A2 TKT EIF5A

5.90e-041641215C0007097
DiseaseColorectal Carcinoma

MTHFD1L ADAM29 GRIK3 ABCA10 ABCA9 FAT1 SPAG17 NODAL CUX1 EXOC4

6.45e-0470212110C0009402
Diseaseurinary albumin to creatinine ratio

CACNA1S RAPH1 STAB1 FAT1 FBXL20

8.75e-041791215EFO_0007778
DiseaseCongenital Abnormality

EYA1 GRK2

8.95e-04111212C0000768
Diseasecalcium measurement

ESRRG EYA1 ABCA9 CILP2 SLC12A2 ABCC12 FBXL20 POLQ ATP2B1

1.16e-036281219EFO_0004838
DiseasePolydactyly

TCTN3 USP9X TMEM216 SALL4

1.40e-031171214C0152427
Diseaseautosomal recessive polycystic kidney disease (implicated_via_orthology)

PKD1 CDC25A

1.93e-03161212DOID:0110861 (implicated_via_orthology)
DiseaseAnimal Mammary Neoplasms

GDA SLC12A2 TKT EIF5A

2.83e-031421214C0024667
DiseaseMammary Carcinoma, Animal

GDA SLC12A2 TKT EIF5A

2.83e-031421214C1257925
DiseaseFamilial aplasia of the vermis

TCTN3 TMEM216

3.02e-03201212cv:C0431399
Diseaseadiponectin measurement

STAB1 EIF5AL1 PBRM1 EIF5A

3.12e-031461214EFO_0004502
Diseasebreast carcinoma

ESRRG ADAM29 POU5F1B EPB41L3 EIF5AL1 SLC12A2 INSC EIF5A SPAG17 DPY19L2P2 CUX1

3.19e-03101912111EFO_0000305
Diseasephosphatidylcholine 34:3 measurement

METTL4 SNX29

3.65e-03221212EFO_0010377
Diseasecoronary artery disease

CLTCL1 CIART MTHFD1L EFCAB13 OPHN1 EPG5 GRK3 CDC123 FBXL20 CORO7 CDC25A ATP2B1

3.71e-03119412112EFO_0001645
DiseaseNonsyndromic genetic hearing loss

ESRRB TECTA GSDME

3.80e-03761213cv:C5680182
Diseasereticulocyte count

EPRS1 KLHL10 USP9X EYA1 FAT1 ACSBG1 PKD1 C4BPA FBXL20 ATP2B1 CUX1

3.85e-03104512111EFO_0007986
DiseaseMammary Neoplasms, Experimental

GDA SLC12A2 TKT EIF5A

3.87e-031551214C0024668
Diseasereticulocyte measurement

KLHL10 USP9X EYA1 FAT1 SLC12A2 ACSBG1 C4BPA FBXL20 CORO7 ATP2B1 CUX1

4.08e-03105312111EFO_0010700

Protein segments in the cluster

PeptideGeneStartEntry
TKDIFNVKRCGNGVV

ADAM29

391

Q9UKF5
DTIVFKCQKGFVLRG

C4BPA

261

P04003
LGQVFISGIKSECRK

EPG5

1701

Q9HCE0
AKCKVVITFNQGLRG

ACSS1

211

Q9NUB1
LFRIKGGKQFVLQCE

GRK3

621

P35626
GFQNLKKRDEVICRF

ANTXRL

276

A6NF34
IGFSKGCVVLNQLLF

C2orf69

261

Q8N8R5
AIRNVSFCVKKGEVL

ABCA10

1221

Q8WWZ4
QVLFSADDRVKKCIG

ALDOC

61

P09972
LAKNGICQRIFGEKV

CUX1

956

P39880
NVSFCVKKGEVIGLL

ABCA9

1311

Q8IUA7
NILITKQGIIKICDF

CDKL4

131

Q5MAI5
KQGIIKICDFGFAQI

CDKL4

136

Q5MAI5
VKLDGQFEFCLLRGK

GSDME

226

O60443
CIIRSVFLGKIKDAF

PGD

366

P52209
GSFIRLKQFLEKCLQ

GLE1

666

Q53GS7
GVIFLTKKGRQVCAK

CCL15

81

Q16663
AQSLGFKINFLCKIR

DIAPH2

851

O60879
CAEVLESFFVQKLKG

BPTF

3016

Q12830
EKFFNIKCRASGLVP

MTHFD1L

721

Q6UB35
EKLVGRVNLKECFTA

DSC2

46

Q02487
FLKEFQVCADKVLGI

ARMCX3

336

Q9UH62
CFKILSANGEAKVFR

ATP2B1

611

P20020
LLKIRGGKQFILQCD

GRK2

621

P25098
KFLATDKVFCVGQLV

AOX1

661

Q06278
LLNFKAVCEETLKVG

CLYBL

176

Q8N0X4
GEVRCVKIFAKGTLA

NWD1

911

Q149M9
FLNKDFLELRKACGI

RBM44

556

Q6ZP01
GKAKVSRDLVCFLQL

RAPH1

431

Q70E73
VFRVGNNFLRLCVLK

INTS7

71

Q9NVH2
ELNEVGFKFVRKCIN

OPHN1

381

O60890
GFKFVRKCINIIETK

OPHN1

386

O60890
LGVLFGKVFSQKTIC

POU5F1B

171

Q06416
IGVRILNVFQKLCAG

FAT1

3726

Q14517
EIIKDIFQRGKICFI

MTHFS

66

P49914
FRKRKVISFGGCIAQ

OR4F21

86

O95013
FFIKIRDELCKNGEI

PBRM1

871

Q86U86
FLVVIFLKGNCANKE

MAGEB5

136

Q9BZ81
QCSALRKNGFVVLKG

EIF5A2

21

Q9GZV4
ALVGTACKDKQLRIF

CORO7

181

P57737
RVEKEVISGKGQFFC

FRA10AC1

161

Q70Z53
RFNIIFNKCLAGSKG

HS3ST5

296

Q8IZT8
QRKVISFKGCLVQIF

OR4F5

81

Q8NH21
SFGKVKQCVNFVIGL

PEX2

131

P28328
KIGKESCFERIIQRF

EYA1

531

Q99502
VFICRGKEDALVTKN

FBL

96

P22087
FAGFQRKAVVVCPKD

HNRNPU

596

Q00839
LFKCICIRAQFGGKI

PHRF1

151

Q9P1Y6
AKGFDFKTCNVLVAL

MAT1A

96

Q00266
QCSALRKNGFVVLKG

EIF5A

21

P63241
LCVKFVKVFSRIFGE

PRSS37

176

A4D1T9
QRKVISFKGCLVQIF

OR4F17

81

Q8NGA8
AKIFGIQSFCKDLVE

GRPEL2

101

Q8TAA5
RNLKEKCFVTQLAGF

NBPF1

36

Q3BBV0
KFVCKPGARNITVIF

EXOC4

486

Q96A65
GICFFHAIIQERKKF

DNAH6

3691

Q9C0G6
EKLAELRKLCQGLFF

HYOU1

796

Q9Y4L1
QCSALRKNGFVVLKG

EIF5AL1

21

Q6IS14
GKLCDVVIKVNGFEF

KLHL10

36

Q6JEL2
FGQRLLVKCLSLKFE

DOCK7

261

Q96N67
AEFRCFVKENKLIGI

CDC123

176

O75794
GVQLFKGKFFRCTDL

CACNA1S

946

Q13698
EACKAFFKRTIQGNI

ESRRG

146

P62508
VKNCKRDGFVQTILG

POLQ

2431

O75417
FVLKILERDQQICKG

CENPJ

596

Q9HC77
RAAVEVFGKLKDLNC

HAUS7

26

Q99871
LVLAKVRQALGFAKC

ACSBG1

431

Q96GR2
AAIKAAQLGFKTVCI

DLD

56

P09622
AFQDALKIFCRIKGG

EFCAB13

221

Q8IY85
KTLGGVIFRKFECAN

LYPD8

186

Q6UX82
IAKEGGVVALFKVCR

INSC

276

Q1MX18
ITDKFGQRAFVGKVC

GDA

156

Q9Y2T3
FISNDKKVVGCLIAE

ESCO1

711

Q5FWF5
GKALSLVIVDQEKCF

EME1

356

Q96AY2
EACKAFFKRTIQGNI

ESRRB

121

O95718
KKACDQLALGVVAIF

GRIK3

96

Q13003
CFIQTLVDVFTKRKG

CASP14

186

P31944
NICGRAFTTKGNLKV

SALL4

901

Q9UJQ4
VEKRSRGQVLFDKVC

EPB41L3

126

Q9Y2J2
GKKRKRCVVFNQGEL

METTL4

131

Q8N3J2
CFIFKKTVGDISRVL

DPY19L2P2

316

Q6ZN68
GKFANLIKEFVIIDC

CDC25A

371

P30304
FCGQRGRFKYEILVK

PKD1

3111

P98161
QTGFQCAVKKVRLEV

MAP3K14

421

Q99558
VLVVICGSVKFEGNK

NXT1

91

Q9UKK6
FRKRKVISFGGCIAQ

OR4F3;

86

Q6IEY1
QRKVISFKGCLVQIF

OR4F4

81

Q96R69
TCFKAEFEQIVLGKR

UPP1

161

Q16831
ERFFKAVNCREGKLV

USP9X

741

Q93008
KGDIIQLQRRGFFIC

EPRS1

666

P07814
FCVKNIKQAEFGRRE

AHCYL2

186

Q96HN2
VKQCQIRFGGRKEIA

SNX29

21

Q8TEQ0
FRVLGCILSELKQKG

SMARCAD1

856

Q9H4L7
RRFCVGLQKIEEIFK

CKM

251

P06732
GVSQLIKAFLRKTEC

LCMT1

76

Q9UIC8
LCRKVKFQVDFNLIG

NODAL

246

Q96S42
ILKEEFRGVIIKQGC

PLEK

236

P08567
VVENISKRCGGFLRK

FBXL20

81

Q96IG2
DQDKLVCKRTFLVLG

SLC9B2

331

Q86UD5
VEKAKIGLIQFCLSA

CCT4

241

P50991
DCFRQIVKAQGVLGL

SLC25A43

251

Q8WUT9
FVVRKGKILGICGNV

ABCC12

501

Q96J65
GFCQQVVRKVAGLDK

SLC25A15

86

Q9Y619
KFLFLKCIGNNLAVV

SPATA1

96

Q5VX52
TVVKLKNVGVDFCRF

SPAG17

2096

Q6Q759
DGIVVSANCKLRKIF

CFAP20DC

31

Q6ZVT6
DLLFAQKCKELQGFI

CIART

116

Q8N365
FRACFLKVKIQGPQE

CILP2

936

Q8IUL8
KFICIREKVGEQAQV

CLTC

36

Q00610
KFICIREKVGEQAQV

CLTCL1

36

P53675
FGCVFAKVSQKLVVA

CHPT1

301

Q8WUD6
TLKKVRIFQDCEAGL

CNGA3

476

Q16281
SKCKLFQLGFEREGV

TECTA

1816

O75443
KLRYFIIEGGCQNLK

TECTA

1991

O75443
AVSVVFPLCQFERKK

RNF212

281

Q495C1
VCKAIIQGKQFEGLV

ERVK-9

11

P63127
VCKAIIQGKQFEGLV

ERVK-24

11

P63129
KAVELAANTKGICFI

TKT

456

P29401
VCKAIIQGKQFEGLV

HERVK_113

11

P63121
DCKIRVFIGGKINRI

SLC12A2

1051

P55011
VCKAIIQGKQFEGLV

ERVK-7

11

P63131
IARLLGTKTCKQVFQ

EZH1

456

Q92800
VCKAIIQGKQFEGLV

ERVK-6

11

Q9Y6I0
VCKAIIQGKQFEGLV

ERVK-25

11

P63125
NGRFEVGKKICLSIS

UBE2J1

81

Q9Y385
SFVRGQVLFKGCDVK

STAB1

21

Q9NY15
VLFIVKSQEKIFCGQ

PROKR2

196

Q8NFJ6
FFQNLGIRCVKKKEV

REL

101

Q04864
VCKAIIQGKQFEGLV

ERVK-10

11

P10265
CKQFVTGGKKLLLFE

VPS41

141

P49754
LKNLFIEAGCSVKAF

PTBP3

491

O95758
QFFLECGGLVRTDKK

USP20

171

Q9Y2K6
AVCREELRQVVFGKK

ZNF598

66

Q86UK7
TCEIFKREKNVGVFQ

TOPAZ1

1071

Q8N9V7
EGCKGFFRRTIQKNL

THRA

71

P10827
NKEVFSCRGIKLAVD

ZC3H12C

261

Q9C0D7
VCKAIIQGKQFEGLV

ERVK-8

11

P63122
QFGVNAISGCKLRLK

TCTN3

421

Q6NUS6
VRECQVLFLAGKTKG

UBR2

1676

Q8IWV8
VIRLFFGTKGNLCQR

TMEM216

71

Q9P0N5
VCKAIIQGKQFEGLV

ERVK-21

11

P63119
KLCFGKQLFLEAVER

TANGO2

166

Q6ICL3
QRDVFILLSKFGICK

TSHR

686

P16473
VCKAIIQGKQFEGLV

HERV-K104

11

P63124
VCKAIIQGKQFEGLV

ERVK-19

11

P63120