Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyBiologicalProcess	homophilic cell adhesion via plasma membrane adhesion molecules	CADM3 PCDHGC4 PCDHGB5 PSG9 CDHR1 CEACAM8 DSCAML1 HMCN2 PCDHGB4	7.17e-06	187	145	9	GO:0007156
GeneOntologyBiologicalProcess	negative regulation of lipid metabolic process	CRTC3 PDE3B PSG9 CEACAM8 NFKB1 SIK2 ALK SORL1	8.70e-06	145	145	8	GO:0045833
GeneOntologyBiologicalProcess	tube morphogenesis	CDK20 TMEM67 CXCR3 PDE3B UTS2R COL15A1 PSG9 IFT172 HIF3A LGR5 TFAP2A LUZP1 RASIP1 AGO1 PXDN RTL1 KLF5 CC2D2A KDM6A MED12 NOTCH1 FOXF1	1.26e-05	1125	145	22	GO:0035239
GeneOntologyBiologicalProcess	tube development	CDK20 TMEM67 CXCR3 PDE3B UTS2R COL15A1 PSG9 IFT172 HIF3A SIM2 LGR5 TFAP2A LUZP1 TYMS RASIP1 AGO1 PXDN RTL1 KLF5 CC2D2A KDM6A BAG6 MED12 NOTCH1 FOXF1	1.46e-05	1402	145	25	GO:0035295
GeneOntologyBiologicalProcess	somitogenesis	DLL3 ATM KDM6A MED12 NOTCH1 FOXF1	1.59e-05	76	145	6	GO:0001756
GeneOntologyBiologicalProcess	pattern specification process	TMEM67 IFT172 SIM2 TFAP2A DSCAML1 MFNG DLL3 CC2D2A ATM KDM6A MED12 NOTCH1 FOXF1 DOP1B	2.13e-05	526	145	14	GO:0007389
GeneOntologyBiologicalProcess	primary neural tube formation	CDK20 IFT172 TFAP2A LUZP1 CC2D2A KDM6A MED12	2.25e-05	120	145	7	GO:0014020
GeneOntologyBiologicalProcess	epithelial tube morphogenesis	CDK20 TMEM67 IFT172 LGR5 TFAP2A LUZP1 RASIP1 CC2D2A KDM6A MED12 NOTCH1 FOXF1	4.39e-05	421	145	12	GO:0060562
GeneOntologyBiologicalProcess	neural tube formation	CDK20 IFT172 TFAP2A LUZP1 CC2D2A KDM6A MED12	4.58e-05	134	145	7	GO:0001841
GeneOntologyBiologicalProcess	somite development	DLL3 ATM KDM6A MED12 NOTCH1 FOXF1	5.33e-05	94	145	6	GO:0061053
GeneOntologyBiologicalProcess	tube formation	CDK20 IFT172 TFAP2A LUZP1 CC2D2A KDM6A MED12 NOTCH1	5.43e-05	187	145	8	GO:0035148
GeneOntologyBiologicalProcess	morphogenesis of embryonic epithelium	CDK20 IFT172 TFAP2A LUZP1 LLGL2 CC2D2A KDM6A MED12	6.08e-05	190	145	8	GO:0016331
GeneOntologyBiologicalProcess	circulatory system development	TMEM67 CXCR3 PDE3B UTS2R COL15A1 PSG9 IFT172 SPEG HIF3A TFAP2A LUZP1 RASIP1 LLGL2 AGO1 PXDN RTL1 KLF5 CC2D2A ATM RBM24 KDM6A MED12 NOTCH1 FOXF1	6.69e-05	1442	145	24	GO:0072359
GeneOntologyBiologicalProcess	cell-cell adhesion via plasma-membrane adhesion molecules	CADM3 PCDHGC4 PCDHGB5 PSG9 CDHR1 CEACAM8 DSCAML1 MAGI2 HMCN2 PCDHGB4	7.60e-05	313	145	10	GO:0098742
GeneOntologyBiologicalProcess	epithelium development	CDK20 TMEM67 FRAS1 PSG9 IFT172 PPHLN1 LGR5 CLOCK TFAP2A LUZP1 TYMS MAGI2 RASIP1 FAM20C LLGL2 KLF5 DLL3 CC2D2A ATM KDM6A HYDIN MED12 NOTCH1 FOXF1	8.93e-05	1469	145	24	GO:0060429
GeneOntologyBiologicalProcess	negative regulation of lipid catabolic process	CRTC3 PDE3B ALK SORL1	9.22e-05	34	145	4	GO:0050995
GeneOntologyBiologicalProcess	neural tube development	CDK20 IFT172 TFAP2A LUZP1 CC2D2A KDM6A MED12 NOTCH1	9.33e-05	202	145	8	GO:0021915
GeneOntologyBiologicalProcess	anatomical structure formation involved in morphogenesis	CDK20 CXCR3 PDE3B UTS2R COL15A1 PSG9 IFT172 HIF3A TFAP2A LUZP1 RASIP1 FAM20C MFNG AGO1 PXDN RTL1 KLF5 DLL3 CC2D2A ATM KDM6A MED12 NOTCH1 FOXF1	1.03e-04	1483	145	24	GO:0048646
GeneOntologyBiologicalProcess	morphogenesis of an epithelium	CDK20 TMEM67 FRAS1 IFT172 LGR5 TFAP2A LUZP1 RASIP1 LLGL2 CC2D2A KDM6A MED12 NOTCH1 FOXF1	1.22e-04	619	145	14	GO:0002009
GeneOntologyBiologicalProcess	embryonic epithelial tube formation	CDK20 IFT172 TFAP2A LUZP1 CC2D2A KDM6A MED12	1.34e-04	159	145	7	GO:0001838
GeneOntologyBiologicalProcess	neural tube closure	CDK20 IFT172 TFAP2A CC2D2A KDM6A MED12	1.48e-04	113	145	6	GO:0001843
GeneOntologyBiologicalProcess	tube closure	CDK20 IFT172 TFAP2A CC2D2A KDM6A MED12	1.56e-04	114	145	6	GO:0060606
GeneOntologyBiologicalProcess	chordate embryonic development	CDK20 IFT172 SPEG TFAP2A DSCAML1 LUZP1 MFNG LLGL2 RTL1 SUV39H1 DLL3 CC2D2A ATM KDM6A MED12 NOTCH1 FOXF1	2.17e-04	906	145	17	GO:0043009
GeneOntologyBiologicalProcess	epithelial tube formation	CDK20 IFT172 TFAP2A LUZP1 CC2D2A KDM6A MED12	2.26e-04	173	145	7	GO:0072175
GeneOntologyBiologicalProcess	segmentation	DLL3 ATM KDM6A MED12 NOTCH1 FOXF1	2.35e-04	123	145	6	GO:0035282
GeneOntologyBiologicalProcess	embryo development ending in birth or egg hatching	CDK20 IFT172 SPEG TFAP2A DSCAML1 LUZP1 MFNG LLGL2 RTL1 SUV39H1 DLL3 CC2D2A ATM KDM6A MED12 NOTCH1 FOXF1	2.91e-04	929	145	17	GO:0009792
HumanPheno	Abnormality of calvarial morphology	TMEM67 FRAS1 PCDHGC4 EBF3 MMP23B CHD3 ADAR YWHAG TFAP2A BRWD3 LUZP1 FAM20C AGO1 WASHC5 RTL1 NFKB1 SCN4A DLL3 TONSL CC2D2A MBD5 KDM6A KYNU PHIP MED12 NOTCH1 MAN1B1 FOXF1	1.02e-05	1134	58	28	HP:0002648
MousePheno	delayed somite formation	DLL3 KDM6A NOTCH1 FOXF1	1.02e-05	16	125	4	MP:0003794
Domain	G2F	NID2 HMCN2	3.60e-04	4	146	2	PF07474
Domain	COE	EBF3 EBF1	3.60e-04	4	146	2	PS01345
Domain	NIDOGEN_G2	NID2 HMCN2	3.60e-04	4	146	2	PS50993
Domain	Transcription_factor_COE	EBF3 EBF1	3.60e-04	4	146	2	IPR003523
Domain	GFP	NID2 HMCN2	3.60e-04	4	146	2	IPR009017
Domain	COE_HLH	EBF3 EBF1	3.60e-04	4	146	2	IPR032201
Domain	COE_DBD	EBF3 EBF1	3.60e-04	4	146	2	IPR032200
Domain	Transcription_factor_COE_CS	EBF3 EBF1	3.60e-04	4	146	2	IPR018350
Domain	COE1_HLH	EBF3 EBF1	3.60e-04	4	146	2	PF16423
Domain	COE1_DBD	EBF3 EBF1	3.60e-04	4	146	2	PF16422
Domain	G2_nidogen/fibulin_G2F	NID2 HMCN2	3.60e-04	4	146	2	IPR006605
Pubmed	Dynamic Protein Interactions of the Polycomb Repressive Complex 2 during Differentiation of Pluripotent Cells.	CHD3 LUZP1 LIG1 NIFK AAAS YKT6 PRRC2C NFKB1 KDM6A BAG6 PHIP HYDIN MOV10	1.53e-07	469	151	13	27634302
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	FRAS1 ZSWIM5 IFT172 SPEG R3HDM2 ERBIN MAGI2 GANAB PXDN PRRC2C ARHGAP21 DOP1B	2.44e-07	407	151	12	12693553
Pubmed	Herpesvirus deconjugases inhibit the IFN response by promoting TRIM25 autoubiquitination and functional inactivation of the RIG-I signalosome.	MARS1 XPO1 ADAR YWHAG BAG6 MOV10	4.86e-07	67	151	6	29357390
Pubmed	Proteomic analyses reveal distinct chromatin-associated and soluble transcription factor complexes.	CDK20 UTP6 EBF3 RBL2 SIM2 ADAR TFAP2A MDN1 PRRC2C NFKB1 ADGRL2 NOTCH1 FOXF1 MOV10 SORL1	5.36e-06	857	151	15	25609649
Pubmed	Integrative genomic analysis of early neurogenesis reveals a temporal genetic program for differentiation and specification of preplate and Cajal-Retzius neurons.	CALB2 EBF3 EBF1 JPH3	5.54e-06	27	151	4	33760820
Pubmed	Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein.	DIP2B FRAS1 PDE3B CHD3 LLGL2 WASHC5 PRRC2C TONSL SIK2 KYNU ARHGAP21 MAN1B1 SORL1	5.72e-06	650	151	13	38777146
Pubmed	Prediction of the coding sequences of unidentified human genes. XVII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.	DIP2B RELCH FRAS1 UBAP2 ZSWIM5 MBD5	6.13e-06	103	151	6	10819331
Pubmed	Notch1 expression and ligand interactions in progenitor cells of the mouse olfactory epithelium.	MFNG DLL3 NOTCH1	6.61e-06	9	151	3	17605079
Pubmed	Localisation of members of the notch system and the differentiation of vibrissa hair follicles: receptors, ligands, and fringe modulators.	MFNG DLL3 NOTCH1	1.29e-05	11	151	3	10878608
Pubmed	Crosstalk between TLR5 and Notch1 signaling in epithelial cells during intestinal inflammation.	TLR5 NOTCH1	1.87e-05	2	151	2	24048326
Pubmed	[Proteasome inhibitor induces apoptosis and influences the expression of Notch1 and NF-kappaB in multiple myeloma RPMI8226 cells].	NFKB1 NOTCH1	1.87e-05	2	151	2	18549623
Pubmed	Inhibitory effect of curcumin on oral carcinoma CAL-27 cells via suppression of Notch-1 and NF-κB signaling pathways.	NFKB1 NOTCH1	1.87e-05	2	151	2	21308734
Pubmed	Induction of Epstein-Barr Virus Oncoprotein LMP1 by Transcription Factors AP-2 and Early B Cell Factor.	EBF1 TFAP2A	1.87e-05	2	151	2	26819314
Pubmed	CRM1 mediates the export of ADAR1 through a nuclear export signal within the Z-DNA binding domain.	XPO1 ADAR	1.87e-05	2	151	2	11604520
Pubmed	NACK is an integral component of the Notch transcriptional activation complex and is critical for development and tumorigenesis.	PRAG1 NOTCH1	1.87e-05	2	151	2	25038227
Pubmed	Nuclear factor κB-dependent neurite remodeling is mediated by Notch pathway.	NFKB1 NOTCH1	1.87e-05	2	151	2	21832199
Pubmed	[Notch1 signaling participates in the release of inflammatory mediators in mouse RAW264.7 cells via activating NF-κB pathway].	NFKB1 NOTCH1	1.87e-05	2	151	2	29169413
Pubmed	Down-regulation of EBV-LMP1 radio-sensitizes nasal pharyngeal carcinoma cells via NF-κB regulated ATM expression.	NFKB1 ATM	1.87e-05	2	151	2	22096476
Pubmed	Association analyses of the interaction between the ADSS and ATM genes with schizophrenia in a Chinese population.	ADSS2 ATM	1.87e-05	2	151	2	19115993
Pubmed	Notch inhibition in Kaposi's sarcoma tumor cells leads to mitotic catastrophe through nuclear factor-kappaB signaling.	NFKB1 NOTCH1	1.87e-05	2	151	2	17604336
Pubmed	Inhibition of SUV39H1 reduces tumor angiogenesis via Notch1 in oral squamous cell carcinoma.	SUV39H1 NOTCH1	1.87e-05	2	151	2	38650654
Pubmed	Interaction between NF-κB signaling and Notch signaling in gliogenesis of mouse mesencephalic neural crest cells.	NFKB1 NOTCH1	1.87e-05	2	151	2	21983543
Pubmed	Tumor necrosis factor-α and interferon-γ stimulate MUC16 (CA125) expression in breast, endometrial and ovarian cancers through NFκB.	MUC16 NFKB1	1.87e-05	2	151	2	26918940
Pubmed	Increased levels of NOTCH1, NF-kappaB, and other interconnected transcription factors characterize primitive sets of hematopoietic stem cells.	NFKB1 NOTCH1	1.87e-05	2	151	2	19686049
Pubmed	Krüppel-Like Factor 5 Promotes Epithelial Proliferation and DNA Damage Repair in the Intestine of Irradiated Mice.	LGR5 KLF5	1.87e-05	2	151	2	26681925
Pubmed	Human Notch-1 inhibits NF-kappa B activity in the nucleus through a direct interaction involving a novel domain.	NFKB1 NOTCH1	1.87e-05	2	151	2	11418662
Pubmed	Regulation of T-cell receptor D beta 1 promoter by KLF5 through reiterated GC-rich motifs.	ZNF600 KLF5	1.87e-05	2	151	2	12576331
Pubmed	Respiratory syncytial virus promoted the differentiation of Th17 cells in airway microenvironment through activation of Notch-1/Delta3.	DLL3 NOTCH1	1.87e-05	2	151	2	30843783
Pubmed	Notch1 induces cell cycle arrest and apoptosis in human cervical cancer cells: involvement of nuclear factor kappa B inhibition.	NFKB1 NOTCH1	1.87e-05	2	151	2	17316355
Pubmed	Early B-cell factors 2 and 3 (EBF2/3) regulate early migration of Cajal-Retzius cells from the cortical hem.	CALB2 EBF3 EBF1	2.22e-05	13	151	3	22421355
Pubmed	MTG8 interacts with LHX6 to specify cortical interneuron subtype identity.	CALB2 EBF1 DLL3 NOTCH1	2.50e-05	39	151	4	36064547
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	DIP2B CRTC3 PDE3B UBAP2 PRAG1 ERBIN YWHAG LUZP1 MDN1 PRRC2C SIK2 ARHGAP21 KLC3 DOP1B	2.52e-05	861	151	14	36931259
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	FRAS1 ARSJ FNTB SPEG PRAG1 HDDC3 FAM20C LLGL2 MDN1 PLA2G4B MBD5 ALKBH6 ARHGAP21 MED12 NOTCH1 ABCC10	2.69e-05	1105	151	16	35748872
Pubmed	TRIM65 regulates microRNA activity by ubiquitination of TNRC6.	UBAP2 ADAR ADARB2 NIFK AGO1 PNRC1 BAG6 MOV10 SORL1	3.27e-05	364	151	9	24778252
Pubmed	Functional genomic landscape of cancer-intrinsic evasion of killing by T cells.	UTP6 FAXC DHX33 TFAP2A GANAB SMG7 MSMO1 MTRR MED12 FOXF1	3.35e-05	457	151	10	32968282
Pubmed	Expression of Notch pathway genes in the embryonic mouse metanephros suggests a role in proximal tubule development.	MFNG DLL3 NOTCH1	3.51e-05	15	151	3	12971992
Pubmed	Prdm13 is required for Ebf3+ amacrine cell formation in the retina.	CALB2 EBF3 TFAP2A	4.31e-05	16	151	3	29258872
Pubmed	Expression of Notch pathway components in fetal and adult mouse small intestine.	MFNG DLL3 NOTCH1	4.31e-05	16	151	3	12617809
Pubmed	Human transcription factor protein interaction networks.	UBAP2 MARS1 R3HDM2 CHD3 ERBIN NIFK PHC3 CHCHD4 GANAB AGO1 SMG7 PRRC2C KLF5 NFKB1 PCCA KDM6A MOV10 SORL1	5.13e-05	1429	151	18	35140242
Pubmed	Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.	RELCH XPO1 ERBIN YWHAG TFAP2A LUZP1 NIFK AAAS GANAB SMG7 WASHC5 NFKB1 ADGRL2 KDM6A NOTCH1	5.58e-05	1049	151	15	27880917
Pubmed	Cellular aspect ratio and cell division mechanics underlie the patterning of cell progeny in diverse mammalian epithelia.	LGR5 NOTCH1	5.60e-05	3	151	2	29897330
Pubmed	Combined stimulation of Toll-like receptor 5 and NOD1 strongly potentiates activity of NF-κB, resulting in enhanced innate immune reactions and resistance to Salmonella enterica serovar Typhimurium infection.	NFKB1 TLR5	5.60e-05	3	151	2	23897616
Pubmed	Interactions of 5'-UTR thymidylate synthase polymorphism with 677C → T methylene tetrahydrofolate reductase and 66A → G methyltetrahydrofolate homocysteine methyl-transferase reductase polymorphisms determine susceptibility to coronary artery disease.	TYMS MTRR	5.60e-05	3	151	2	20962453
Pubmed	Fringe modifies O-fucose on mouse Notch1 at epidermal growth factor-like repeats within the ligand-binding site and the Abruptex region.	MFNG NOTCH1	5.60e-05	3	151	2	12486116
Pubmed	1, 25(OH)2D3-induced interaction of vitamin D receptor with p50 subunit of NF-κB suppresses the interaction between KLF5 and p50, contributing to inhibition of LPS-induced macrophage proliferation.	KLF5 NFKB1	5.60e-05	3	151	2	27856242
Pubmed	Krüppel-like Factor 5 Regulates Stemness, Lineage Specification, and Regeneration of Intestinal Epithelial Stem Cells.	LGR5 KLF5	5.60e-05	3	151	2	31778829
Pubmed	Cloning and chromosomal mapping of three novel genes, GPR9, GPR10, and GPR14, encoding receptors related to interleukin 8, neuropeptide Y, and somatostatin receptors.	CXCR3 UTS2R	5.60e-05	3	151	2	8666380
Pubmed	T cell leukemia-associated human Notch/translocation-associated Notch homologue has I kappa B-like activity and physically interacts with nuclear factor-kappa B proteins in T cells.	NFKB1 NOTCH1	5.60e-05	3	151	2	8642313
Pubmed	Purinergic signaling is required for fluid shear stress-induced NF-κB translocation in osteoblasts.	P2RX7 NFKB1	5.60e-05	3	151	2	21237152
Pubmed	Mutations in 3 genes (MKS3, CC2D2A and RPGRIP1L) cause COACH syndrome (Joubert syndrome with congenital hepatic fibrosis).	TMEM67 CC2D2A	5.60e-05	3	151	2	19574260
Pubmed	A promoter-proximal transcript targeted by genetic polymorphism controls E-cadherin silencing in human cancers.	AGO1 SUV39H1	5.60e-05	3	151	2	28555645
Pubmed	The intracellular region of Notch ligands Dll1 and Dll3 regulates their trafficking and signaling activity.	DLL3 NOTCH1	5.60e-05	3	151	2	18676613
Pubmed	Regulation of platelet-derived growth factor-A chain by Krüppel-like factor 5: new pathway of cooperative activation with nuclear factor-kappaB.	KLF5 NFKB1	5.60e-05	3	151	2	14573617
Pubmed	Association of XPO1 Overexpression with NF-κB and Ki67 in Colorectal Cancer.	XPO1 NFKB1	5.60e-05	3	151	2	31870117
Pubmed	Loss of transcription factor KLF5 in the context of p53 ablation drives invasive progression of human squamous cell cancer.	KLF5 NOTCH1	5.60e-05	3	151	2	21868761
Pubmed	ATM-dependent activation of SIM2s regulates homologous recombination and epithelial-mesenchymal transition.	SIM2 ATM	5.60e-05	3	151	2	30531838
Pubmed	The p53 transcriptional pathway is preserved in ATMmutated and NOTCH1mutated chronic lymphocytic leukemias.	ATM NOTCH1	5.60e-05	3	151	2	25587027
Pubmed	The characterization of the Olf-1/EBF-like HLH transcription factor family: implications in olfactory gene regulation and neuronal development.	EBF3 EBF1	5.60e-05	3	151	2	9151732
Pubmed	P2X7 receptor positively regulates MyD88-dependent NF-κB activation.	P2RX7 NFKB1	5.60e-05	3	151	2	21621419
Pubmed	Fringe is a glycosyltransferase that modifies Notch.	MFNG NOTCH1	5.60e-05	3	151	2	10935626
Pubmed	Conditioned medium mimicking the tumor microenvironment augments chemotherapeutic resistance via ataxia‑telangiectasia mutated and nuclear factor‑κB pathways in gastric cancer cells.	NFKB1 ATM	5.60e-05	3	151	2	30106453
Pubmed	Prognostic Impact of LGR5, Prox1, and Notch1 Biomarkers in Stage II to III Colon Cancer.	LGR5 NOTCH1	5.60e-05	3	151	2	34657081
Pubmed	A CRM1-dependent nuclear export signal controls nucleocytoplasmic translocation of HSCARG, which regulates NF-κB activity.	XPO1 NFKB1	5.60e-05	3	151	2	22348310
Pubmed	Unidirectional and stage-dependent roles of Notch1 in Wnt-responsive Lgr5+ cells during mouse inner ear development.	LGR5 NOTCH1	5.60e-05	3	151	2	31598881
Pubmed	Nuclear factor-(kappa)B modulates the p53 response in neurons exposed to DNA damage.	NFKB1 ATM	5.60e-05	3	151	2	15044535
Pubmed	Inhibition of MAPK and NF-κB signaling pathways alleviate carbon tetrachloride (CCl4)-induced liver fibrosis in Toll-like receptor 5 (TLR5) deficiency mice.	NFKB1 TLR5	5.60e-05	3	151	2	26845355
Pubmed	The tumor suppressor Rb and its related Rbl2 genes are regulated by Utx histone demethylase.	RBL2 KDM6A	5.60e-05	3	151	2	20650264
Pubmed	JMJD3 and NF-κB-dependent activation of Notch1 gene is required for keratinocyte migration during skin wound healing.	NFKB1 NOTCH1	5.60e-05	3	151	2	28747631
Pubmed	Notch1 augments NF-kappaB activity by facilitating its nuclear retention.	NFKB1 NOTCH1	5.60e-05	3	151	2	16319921
Pubmed	Notch-1 signaling activates NF-κB in human breast carcinoma MDA-MB-231 cells via PP2A-dependent AKT pathway.	NFKB1 NOTCH1	5.60e-05	3	151	2	26945854
Pubmed	Aberrant fucosylation sustains the NOTCH and EGFR/NF-κB pathways and has a prognostic value in human intrahepatic cholangiocarcinoma.	NFKB1 NOTCH1	5.60e-05	3	151	2	36789652
Pubmed	Suv39h1 mediates AP-2α-dependent inhibition of C/EBPα expression during adipogenesis.	TFAP2A SUV39H1	5.60e-05	3	151	2	24732798
Pubmed	Singleminded-2s (Sim2s) promotes delayed involution of the mouse mammary gland through suppression of Stat3 and NFκB.	SIM2 NFKB1	5.60e-05	3	151	2	21292822
Pubmed	Hes5 expression in the postnatal and adult mouse inner ear and the drug-damaged cochlea.	CALB2 NOTCH1	5.60e-05	3	151	2	19373512
Pubmed	Study of the roles of caspase-3 and nuclear factor kappa B in myenteric neurons in a P2X7 receptor knockout mouse model of ulcerative colitis.	P2RX7 NFKB1	5.60e-05	3	151	2	37389242
Pubmed	Papillomavirus-mediated neoplastic progression is associated with reciprocal changes in JAGGED1 and manic fringe expression linked to notch activation.	MFNG NOTCH1	5.60e-05	3	151	2	15280477
Pubmed	Targeting Notch1 and IKKα Enhanced NF-κB Activation in CD133+ Skin Cancer Stem Cells.	NFKB1 NOTCH1	5.60e-05	3	151	2	29959199
Pubmed	Notch is a direct negative regulator of the DNA-damage response.	ATM NOTCH1	5.60e-05	3	151	2	25895060
Pubmed	Unfractionated heparin suppresses lipopolysaccharide-induced monocyte chemoattractant protein-1 expression in human microvascular endothelial cells by blocking Krüppel-like factor 5 and nuclear factor-κB pathway.	KLF5 NFKB1	5.60e-05	3	151	2	25023776
Pubmed	In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.	PCDHGC4 PCDHGB5 ZSWIM5 CHD3 ERBIN YWHAG LUZP1 NFE2L3 MFNG MDN1 PXDN SACS PRRC2C SCN4A PCDHGB4 CC2D2A ATM ARHGAP21	5.76e-05	1442	151	18	35575683
Pubmed	Irisin Mediates Effects on Bone and Fat via αV Integrin Receptors.	NID2 UBAP2 SPEG XPO1 ADAR YWHAG LUZP1 ME3 MAGI2 LIG1 CHCHD4 AAAS GANAB GVINP1 MSMO1 PCCA BAG6 MAN1B1	6.24e-05	1451	151	18	30550785
Pubmed	Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.	UTP6 MARS1 DHX33 XPO1 ADAR ERBIN YWHAG LUZP1 NIFK AAAS MDN1 ADSS2 WASHC5 BAG6 PHIP MED12 MOV10	8.66e-05	1353	151	17	29467282
Pubmed	Atlas of gene expression in the developing kidney at microanatomic resolution.	SIM2 TFAP2A ME3 FOXF1	9.12e-05	54	151	4	19000842
Pubmed	Proteomic analysis of human parotid gland exosomes by multidimensional protein identification technology (MudPIT).	ATP6V1B1 PCDHGB5 MUC16 ANGPTL1 YWHAG FAM20C GANAB LPO DOP1B	9.27e-05	417	151	9	19199708
Pubmed	A Human Tyrosine Phosphatase Interactome Mapped by Proteomic Profiling.	UTP6 DIP2B FNTB IFT172 XPO1 YWHAG LUZP1 TYMS AAAS GANAB ADGRL2 BAG6 MAN1B1 SORL1	9.45e-05	974	151	14	28675297
Pubmed	The Tbr2 Molecular Network Controls Cortical Neuronal Differentiation Through Complementary Genetic and Epigenetic Pathways.	EBF3 EBF1 KDM6A	1.01e-04	21	151	3	27600842
Pubmed	The RNA binding protein MEX3A promotes tumor progression of breast cancer by post-transcriptional regulation of IGFBP4.	CHD3 ADAR TRMU PXDN SACS PRRC2C NFKB1 ADGRL2	1.08e-04	332	151	8	37433992
Pubmed	Association of maternal polymorphisms in folate metabolizing genes with chromosome damage and risk of Down syndrome offspring.	TYMS MTRR	1.12e-04	4	151	2	18983896
Pubmed	One-carbon metabolism-related gene polymorphisms and risk of head and neck squamous cell carcinoma: case-control study.	TYMS MTRR	1.12e-04	4	151	2	17596206
Pubmed	Notch signalling pathway mediates hair cell development in mammalian cochlea.	DLL3 NOTCH1	1.12e-04	4	151	2	10080181
Pubmed	Identification of novel argonaute-associated proteins.	AGO1 MOV10	1.12e-04	4	151	2	16289642
Pubmed	Gene-gene interactions in the folate metabolic pathway influence the risk for acute lymphoblastic leukemia in children.	TYMS MTRR	1.12e-04	4	151	2	17454638
Pubmed	KLF5 regulates the integrity and oncogenicity of intestinal stem cells.	LGR5 KLF5	1.12e-04	4	151	2	24626089
Pubmed	Notch signaling protects retina from nuclear factor-κB- and poly-ADP-ribose-polymerase-mediated apoptosis under high-glucose stimulation.	NFKB1 NOTCH1	1.12e-04	4	151	2	21813561
Pubmed	Epigenetic regulation of HYAL-1 hyaluronidase expression. identification of HYAL-1 promoter.	TFAP2A NFKB1	1.12e-04	4	151	2	18718911
Pubmed	Re-sequencing of candidate genes FOXF1, HSPA6, HAAO, and KYNU in 522 individuals with VATER/VACTERL, VACTER/VACTERL-like association, and isolated anorectal malformation.	KYNU FOXF1	1.12e-04	4	151	2	35362267
Pubmed	Notch signalling is linked to epidermal cell differentiation level in basal cell carcinoma, psoriasis and wound healing.	MFNG NOTCH1	1.12e-04	4	151	2	11978185
Pubmed	Significance of the transcription factor KLF5 in cardiovascular remodeling.	KLF5 NFKB1	1.12e-04	4	151	2	16102021
Pubmed	SUMOylation regulates nuclear localization of Krüppel-like factor 5.	XPO1 KLF5	1.12e-04	4	151	2	18782761
Pubmed	The single IgG IL-1-related receptor controls TLR responses in differentiated human intestinal epithelial cells.	NFKB1 TLR5	1.12e-04	4	151	2	20130217
Coexpression	BOYAULT_LIVER_CANCER_SUBCLASS_G1_UP	UBAP2 ADAR LLGL2 SMG7 PRRC2C TLR5 ABCC10	4.84e-06	116	150	7	M14146
Coexpression	GSE17721_POLYIC_VS_CPG_16H_BMDC_UP	EBF3 SPEG SLC22A23 ADAR BRWD3 ATM PHIP DOP1B	2.08e-05	200	150	8	M3950
Coexpression	GSE11924_TH1_VS_TH2_CD4_TCELL_UP	ARHGAP9 RSPH6A MFNG AAAS SMG7 MCM9 BAG6 KLC3	2.08e-05	200	150	8	M3159
Coexpression	PEDERSEN_METASTASIS_BY_ERBB2_ISOFORM_6	AOX1 PRAG1 SACS RBM24	2.19e-05	29	150	4	M2412
CoexpressionAtlas	placenta	CADM3 NID2 ATP6V1B1 COL15A1 PSG9 HIF3A LGR5 ANGPTL1 TFAP2A NFE2L3 RTL1 SP6	6.81e-06	349	149	12	placenta
ToppCell	facs-Marrow-T_cells-18m-Lymphocytic-Klrb1a/b/c(-)_NK_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CXCR3 DRP2 CHD3 SIT1 P2RX7 SP6 JPH3 DOP1B	9.82e-08	165	151	8	eeb58d4db64ad37dc6b441eab22b05c24862e1a9
ToppCell	Control-Endothelial-Endothelial-Alv_Cap\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	FRAS1 PDE3B LUZP1 RASIP1 MFNG P2RX7 ADGRL2 ARHGAP21	2.56e-07	187	151	8	ea9d34bcd3bd1f36745846309ede349773de501a
ToppCell	human_hepatoblastoma\|World / Sample and Cell Type and Tumor Cluster (all cells)	FRAS1 HIF3A PRAG1 ERBIN PRRC2C MBD5 KDM6A PHIP	3.26e-07	193	151	8	e6a688bc834f845ff64dae1be64f073eec5091a1
ToppCell	Hippocampus-Endothelial-ENDOTHELIAL_TIP-Dcn_1\|Hippocampus / BrainAtlas - Mouse McCarroll V32	NID2 COL15A1 AOX1 MMP23B CPED1 TFAP2A PCCA	1.21e-06	159	151	7	92049a8d8fc9997d8d0d76500c72596a9b2394e0
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell__prolif\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	COL15A1 TYMS RASIP1 GVINP1 SCN4A SP6 FOXF1	1.75e-06	168	151	7	37249f38f8f04ec5743097259de67b106ca2b02f
ToppCell	droplet-Heart-nan-3m\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL15A1 CPED1 CLOCK ERBIN PRRC2C KDM6A ARHGAP21	2.39e-06	176	151	7	749b47eac5436fa34e0d243ffbc6f1897f4e431e
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	NID2 FRAS1 SIM2 ADARB2 DSCAML1 MAGI2 HYDIN	3.44e-06	186	151	7	f0c8de4f6ae9047b9108a47a2af8c5f42bc103b0
ToppCell	Adult-Endothelial-alveolar_capillary_endothelial_cell_(Cap2;_aerocyte)\|Adult / Lineage, Cell type, age group and donor	HIF3A LGR5 RASIP1 PXDN SP6 ADGRL2 FOXF1	3.69e-06	188	151	7	e5cad03f4a64147fe8174e7f614cf45233ffb9b7
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	NID2 COL15A1 EBF3 EBF1 HIF3A HMCN2 KLF5	3.96e-06	190	151	7	efb757f11c2809e66ddb48a5c84f5433f111cb7c
ToppCell	10x_3'_v3-tissue-resident_(10x_3'_v3)-mesenchymal-mesenchymal-mesenchymal_stem_cell\|tissue-resident_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	NID2 COL15A1 EBF3 AOX1 HIF3A ANGPTL1 PXDN	5.02e-06	197	151	7	3bb92dd8a94e2be3b7fe51c9a21b241215477ac7
ToppCell	10x_3'_v3-tissue-resident_(10x_3'_v3)-mesenchymal\|tissue-resident_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	NID2 COL15A1 EBF3 AOX1 HIF3A ANGPTL1 PXDN	5.02e-06	197	151	7	17344464fdcc5ba0c03959696b97c195f11e644c
ToppCell	10x_3'_v3-tissue-resident_(10x_3'_v3)-mesenchymal-mesenchymal\|tissue-resident_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	NID2 COL15A1 EBF3 AOX1 HIF3A ANGPTL1 PXDN	5.02e-06	197	151	7	5b8d0d7116b20d8e27541e88ec80c9f1f477e384
ToppCell	Brain_organoid-organoid_Velasco_nature-3_mon-Neuronal-Immature_CPNs\|3_mon / Sample Type, Dataset, Time_group, and Cell type.	SLC22A23 CHD3 PRAG1 DISP3 ARHGAP21 DOP1B SORL1	5.19e-06	198	151	7	32d58379a89be19b6b1a494bf033416546771c19
ToppCell	LPS_IL1RA-Epithelial_alveolar-AT_1-Differentiating_AT1\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	NID2 FRAS1 ARSJ SLC22A23 DSCAML1 LLGL2 PLA2G4B	5.19e-06	198	151	7	b598ab958e31f1e98bd06dc0097b58ac3a3f90a3
ToppCell	LPS_anti-TNF-Epithelial_alveolar-AT_1-Differentiating_AT1\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	NID2 FRAS1 SLC22A23 DSCAML1 LLGL2 PLA2G4B KLC3	5.37e-06	199	151	7	d43c605a4ff221cf78d91678c15d2ad20f831c7f
ToppCell	Parenchymal-NucSeq-Endothelial-Endothelia_vascular-VE_alveolar_capillary_Car4_aerocyte\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	PDE3B HIF3A LGR5 RASIP1 PXDN ADGRL2 FOXF1	5.37e-06	199	151	7	dc88ce36cc066eb6c28cfd5b9b60fe07f8cc7b53
ToppCell	3'-Broncho-tracheal-Mesenchymal-Fibroblastic-fibroblastic_type_1-Adventitial_fibroblasts-Adventitial_fibroblasts_L.2.1.2.2\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CADM3 EBF3 AOX1 MMP23B EBF1 ANGPTL1 PXDN	5.37e-06	199	151	7	1fd7bbb8727607e6507848602a19bc86882ef2d5
ToppCell	Parenchymal-10x5prime-Endothelial-Endothelia_vascular-VE_alveolar_capillary_Car4_aerocyte\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	HIF3A LGR5 RASIP1 PXDN SP6 ADGRL2 FOXF1	5.37e-06	199	151	7	14a7c4cf4bb3d43fd32ec9cc74f6625b225ffaa1
ToppCell	Bronchus_Control_(B.)-Stromal-TX-Fibroblasts-2,_SCARA5\|Bronchus_Control_(B.) / Sample group, Lineage and Cell type	CADM3 EBF3 AOX1 MMP23B EBF1 HIF3A ANGPTL1	5.55e-06	200	151	7	2022df85df94ab8cbb4e80e3fe9894c01051c5e0
ToppCell	Tracheal-NucSeq-Epithelial-Epi_submucosal-gland-SMG_Mucous\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	SLC22A23 MUC16 ADARB2 LLGL2 MSMO1 KYNU DOP1B	5.55e-06	200	151	7	c450a15e21fa72d071ed6e3b9f22de557a0f3cea
ToppCell	Bronchus_Control_(B.)-Stromal-TX\|Bronchus_Control_(B.) / Sample group, Lineage and Cell type	CADM3 EBF3 AOX1 MMP23B EBF1 HIF3A ANGPTL1	5.55e-06	200	151	7	69b41f5fb370aa8840a9ad7919d03ef1e57d1b5b
ToppCell	Brain_organoid-organoid_Tanaka_cellReport-10w-Neuronal-Neuron\|10w / Sample Type, Dataset, Time_group, and Cell type.	CDHR1 EBF1 PRAG1 TFAP2A DISP3 PNRC1 ARHGAP21	5.55e-06	200	151	7	332905a686356cd1e024d40679be98e9d8b1b5e8
ToppCell	Tracheal-10x5prime-Stromal-Fibroblastic-Fibro_alveolar\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	CADM3 NID2 AOX1 MMP23B EBF1 ANGPTL1 FAM20C	5.55e-06	200	151	7	3e0041c04e42a47257517dae8707a6454570c256
ToppCell	Brain_organoid-organoid_Tanaka_cellReport-1m-Neuronal-Interneuron\|1m / Sample Type, Dataset, Time_group, and Cell type.	ARSJ EBF3 ZSWIM5 BRWD3 DLL3 ARHGAP21 FOXF1	5.55e-06	200	151	7	fc839e9c33ea1d4ee0f42f21fd32a54e7cbe1f5a
ToppCell	Biopsy_Control_(H.)-Mesenchymal-PLIN2+_Fibroblasts\|Biopsy_Control_(H.) / Sample group, Lineage and Cell type	CADM3 NID2 DRP2 AOX1 MMP23B ANGPTL1 PXDN	5.55e-06	200	151	7	cdaf462b1db29dab61038eeab5ddd3eef3386763
ToppCell	(02)_Cycling_Basal_(regeneration)-(2)_48hpi\|(02)_Cycling_Basal_(regeneration) / shred by cell type and Timepoint	XPO1 ME3 NFE2L3 PNRC1 RBM24 MOV10	1.15e-05	148	151	6	a061a745c09254e063411b7d835d5597a0007e29
ToppCell	facs-Trachea-3m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell-smooth_muscle_cell_of_trachea_l1-41\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	R3HDM2 LGR5 NIFK P2RX7 SUV39H1 MAN1B1	1.67e-05	158	151	6	6d2709b387945c015faa223c20d22b52a4082140
ToppCell	droplet-Heart-nan-18m-Mesenchymal-nan\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL15A1 DRP2 MMP23B DHX33 HDDC3 ATM	2.21e-05	166	151	6	9adceb746e67e955fd8b3e0984f4eed44b64a270
ToppCell	Hippocampus-Endothelial-ENDOTHELIAL_TIP\|Hippocampus / BrainAtlas - Mouse McCarroll V32	NID2 COL15A1 MMP23B CPED1 TFAP2A PCCA	2.36e-05	168	151	6	26aa96b2b547d11941cb803995ea3d302ee0518c
ToppCell	TCGA-Bile_Duct-Primary_Tumor-Cholangiocarcinoma-Intrahepatic-2\|TCGA-Bile_Duct / Sample_Type by Project: Shred V9	TMEM67 CRTC3 TRIM6 TLR5 CC2D2A KLC3	2.36e-05	168	151	6	c70bf73bb800e4722cedc35bbc17ea3113d1012d
ToppCell	PND28-Immune-Immune_Myeloid-Monocytic-Macrophage-iMON-iMON_prolif\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CYP39A1 SIT1 SMG7 GVINP1 SUV39H1 MBD5	2.36e-05	168	151	6	27cdf5cfa1d906868cfd60fdfab3cd51f3b3602f
ToppCell	3'-GW_trimst-2-LargeIntestine-Epithelial-epithelial_progenitor_cell\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CDHR1 LGR5 LLGL2 KLF5 SP6 SLC39A5	2.61e-05	171	151	6	3ef44a5e3e8f81424f1e9aa302860b6688a549b8
ToppCell	3'-GW_trimst-2-LargeIntestine-Epithelial-epithelial_progenitor_cell-Stem_cells\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CDHR1 LGR5 LLGL2 KLF5 SP6 SLC39A5	2.61e-05	171	151	6	3a2fefcb62e9d47ae6b3a946c45d3f2dd32c576c
ToppCell	Frontal_cortex-Neuronal-Inhibitory-iN2(Gad1Gad2)-Cplx3\|Frontal_cortex / BrainAtlas - Mouse McCarroll V32	ADARB2 RTL1 PRRC2C DISP3 ALK	2.80e-05	104	151	5	b5ca6e589f414e549f4990fe334d4ee54829b298
ToppCell	E18.5-Epithelial-Epithelial_Airway-Neurosecretory-PNEC-PNEC_mature\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CADM3 CDHR1 NFE2L3 HMCN2 DLL3 ABCC10	2.87e-05	174	151	6	742c73c9e090848b464323cb17579b86658c6792
ToppCell	E18.5-Epithelial-Epithelial_Airway-Neurosecretory-PNEC\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CADM3 CDHR1 NFE2L3 HMCN2 DLL3 ABCC10	2.87e-05	174	151	6	7fed9722e64c60843092f2ba71256e3043011ef6
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-Adaptive_/_Maladaptive_/_Repairing_Fibroblast\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	PDE3B COL15A1 EBF3 AOX1 CPED1 RBM24	3.16e-05	177	151	6	9ec7f1e64312d26d434b3312b58386715dbad644
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	PDE3B COL15A1 EBF3 AOX1 CPED1 RBM24	3.16e-05	177	151	6	016277dfd59b1793fddaaadc2b3f41622d76ce3a
ToppCell	E17.5-Endothelial-capillary_endothelial_cell-capillary_endothelial_cell_of_alveolus\|E17.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	IFT172 SLC22A23 RASIP1 MFNG ADGRL2 FOXF1	3.26e-05	178	151	6	982205ba117a4c7b7e9b713689a5b69190f0bca9
ToppCell	COPD-Endothelial-VE_Capillary_A\|World / Disease state, Lineage and Cell class	HIF3A RASIP1 PXDN SP6 ADGRL2 FOXF1	3.58e-05	181	151	6	61608123959483ff60f07d8467996853c4371b6a
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	FRAS1 SIM2 ADARB2 DSCAML1 MAGI2 PXDN	3.58e-05	181	151	6	9d782ba5cf5a172cb4f447763fc50e5b13ef7dd9
ToppCell	Adult-Endothelial-alveolar_capillary_endothelial_cell_(Cap2;_aerocyte)-D175\|Adult / Lineage, Cell type, age group and donor	HIF3A LGR5 RASIP1 PXDN ADGRL2 FOXF1	3.70e-05	182	151	6	8b4a07ebd7a133a33ef333cfa29d12c4f3d4d9ac
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_3\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	FRAS1 SIM2 ADARB2 DSCAML1 MAGI2 PXDN	3.70e-05	182	151	6	eb138aa1dca9373f1586600f258df06dcf56d81f
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_2\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	FRAS1 TFAP2A ME3 LLGL2 ADGRL2 SORL1	3.81e-05	183	151	6	2e831a4d99c6f983793df71c0994124c943c6da9
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FRAS1 DRP2 DSCAML1 DISP3 DNAH9 HYDIN	3.93e-05	184	151	6	2cbed6462fea2622871bb7e49b0df3d984239281
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FRAS1 DRP2 DSCAML1 DISP3 DNAH9 HYDIN	3.93e-05	184	151	6	ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FRAS1 DRP2 DSCAML1 DISP3 DNAH9 HYDIN	3.93e-05	184	151	6	2b19a8c5f823e00812908b23e66bb4e563278aff
ToppCell	droplet-Large_Intestine-COLON_PROXIMAL-30m-Epithelial-Lgr5+_undifferentiated_cell\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LGR5 CPED1 MFNG PXDN CC2D2A NOTCH1	3.93e-05	184	151	6	e7b9c69fc77040c5191ad8089697051e2589c30e
ToppCell	COPD-Endothelial-VE_Capillary_A\|COPD / Disease state, Lineage and Cell class	HIF3A RASIP1 PXDN SP6 ADGRL2 FOXF1	3.93e-05	184	151	6	5f4f7775d488ececf086c71441defecbee9d8a9c
ToppCell	droplet-Kidney-KIDNEY-1m-Epithelial-Pecam____kidney_capillary_endothelial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL15A1 SPEG MMP23B PXDN PCDHGB4 HYDIN	3.93e-05	184	151	6	1c857126c0ea0671f0d60b048efca288d348d653
ToppCell	pdx-Tumor_cells-T0\|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)	AOX1 R3HDM2 LGR5 DSCAML1 FAM20C SLC39A5	4.05e-05	185	151	6	1d874608aa2062024323512f68889219471b2f00
ToppCell	390C-Lymphocytic-CD4_T-cell-Treg_cell_1\|390C / Donor, Lineage, Cell class and subclass (all cells)	TBC1D19 CADM3 RBL2 NFE2L3 SUV39H1 RPUSD2	4.17e-05	186	151	6	064b6047215597465bb51a8a1547ef5a226552f9
ToppCell	pdx\|World / Sample and Cell Type and Tumor Cluster (all cells)	FRAS1 ZSWIM5 SLC22A23 R3HDM2 LGR5 LLGL2	4.17e-05	186	151	6	de8e538c8767d41b8a52f5e58ba1affd4e7244c4
ToppCell	pdx-Tumor_cells\|World / Sample and Cell Type and Tumor Cluster (all cells)	FRAS1 ZSWIM5 SLC22A23 R3HDM2 LGR5 LLGL2	4.17e-05	186	151	6	0b88a87158a9ca8de3bf40a4ff1687150707a5f0
ToppCell	LA-01._Fibroblast_I\|World / Chamber and Cluster_Paper	PDE3B COL15A1 AOX1 EBF1 PXDN HMCN2	4.30e-05	187	151	6	4ea486991f66c29728d127171a07b81404ec0b78
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Degenerative_Descending_Thin_Limb_Cell_Type_3\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	NID2 SIM2 ADARB2 DSCAML1 MAGI2 HYDIN	4.30e-05	187	151	6	c31130fc2f9f882944b2ba366a034a03f051c4b9
ToppCell	Adult-Endothelial-capillary_endothelial_cell_(Cap1)-D175\|Adult / Lineage, Cell type, age group and donor	HIF3A RASIP1 PXDN SP6 ADGRL2 FOXF1	4.30e-05	187	151	6	f3548817f2fded5978137bb252cb628ac199e4f6
ToppCell	-Unknown-Endothelial-Myofibroblast\| / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	RELCH PCDHGB5 CPED1 CLOCK LUZP1 MAGI2	4.43e-05	188	151	6	6468fa95ad0395395301115286f2d8c0df5d3882
ToppCell	-Unknown-Endothelial\| / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	RELCH PCDHGB5 CPED1 CLOCK LUZP1 MAGI2	4.43e-05	188	151	6	7a81ac5c79c3eb26639b52d2b9fd5e7ef9798fd6
ToppCell	-Unknown\| / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	RELCH PCDHGB5 CPED1 CLOCK LUZP1 MAGI2	4.43e-05	188	151	6	9cb718bfe1358c6fd842f096e228eb0abb9aefc6
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-Adaptive_/_Maladaptive_/_Repairing_Fibroblast\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	NID2 EBF3 EBF1 HIF3A HMCN2 KLF5	4.43e-05	188	151	6	ce85a56ac27a6432421dde93a1bafa8b943244b9
ToppCell	COVID-19-Heart-Fib_1\|COVID-19 / Disease (COVID-19 only), tissue and cell type	NID2 COL15A1 EBF3 EBF1 PXDN HMCN2	4.43e-05	188	151	6	fe361215f4ba841aa5e1e581fb56f2f4d3ccd201
ToppCell	TCGA-Breast-Primary_Tumor-Breast_Carcinoma-Infiltrating_Lobular_Carcinoma-6\|TCGA-Breast / Sample_Type by Project: Shred V9	UTS2R MMP23B PRAG1 MFNG HMCN2 PLA2G4B	4.43e-05	188	151	6	c90669b51e1902fe7726555290c91c92a911df83
ToppCell	renal_cortex_nuclei-Adult_normal_reference\|renal_cortex_nuclei / Celltypes from Cells and Nuclei per compartment and clinical group	FRAS1 SLC22A23 AOX1 CPNE6 PRRC2C SIK2	4.56e-05	189	151	6	a48df46274d51e84ffb40264646de7346104efb9
ToppCell	Children_(3_yrs)-Endothelial-alveolar_capillary_endothelial_cell_(Cap2;_aerocyte)-D139\|Children_(3_yrs) / Lineage, Cell type, age group and donor	HIF3A LGR5 RASIP1 PXDN ADGRL2 FOXF1	4.70e-05	190	151	6	0a351609a72fd638c84b2435782e312ee6a33aac
ToppCell	3'-GW_trimst-1-LargeIntestine-Neuronal-neuron_precursor\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	EBF3 TFAP2A MFNG DLL3 RBM24 NOTCH1	4.84e-05	191	151	6	a53616c84178eb6c29b48662358765b082df3f97
ToppCell	human_hepatoblastoma-Tumor_cells\|World / Sample and Cell Type and Tumor Cluster (all cells)	FRAS1 HIF3A PRAG1 MBD5 KDM6A PHIP	4.98e-05	192	151	6	916fbec1c7ab7969bda711886ac88e877e30c280
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-Adaptive_/_Maladaptive_/_Repairing_Fibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	NID2 COL15A1 EBF3 EBF1 HIF3A CPED1	5.27e-05	194	151	6	c49f72441b3557e2c3a9c4239e68c0cf0652814b
ToppCell	COPD-Endothelial-VE_Capillary_B\|World / Disease state, Lineage and Cell class	HIF3A RASIP1 PXDN SP6 ADGRL2 FOXF1	5.27e-05	194	151	6	68705a6eca947c5b42b943d5224a7aef2a744007
ToppCell	(5)_Fibroblasts-(5)_Fibroblast-J_(Lipofibroblast)\|(5)_Fibroblasts / Lung cell shreds - cell class (v4) and cell subclass (v4)	CADM3 CALB2 MUC16 NFE2L3 KLF5 PNRC1	5.27e-05	194	151	6	784b15119c91ace33d34bfb3d68c182566a3e9a8
ToppCell	COPD-Endothelial-VE_Capillary_B\|COPD / Disease state, Lineage and Cell class	HIF3A RASIP1 PXDN SP6 ADGRL2 FOXF1	5.27e-05	194	151	6	18b7f901c12ca4f21f9a1eafd092aefe4d668b6d
ToppCell	proximal-Endothelial-Capillary_Aerocyte\|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	PCDHGB5 LGR5 RASIP1 MFNG ADGRL2 FOXF1	5.43e-05	195	151	6	f1cbf82484f489fe7e0b5de6a49ea28d69f04e1a
ToppCell	proximal-Endothelial-Capillary_Aerocyte-3\|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	PCDHGB5 LGR5 RASIP1 MFNG ADGRL2 FOXF1	5.43e-05	195	151	6	13168c9632b58dd65ecb365df3832d95e7325919
ToppCell	PCW_10-12-Mesenchymal-Mesenchymal_fibroblastic-mes_immature5_(6)\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	PDE3B PRAG1 MAGI2 MBD5 ADGRL2 PCCA	5.43e-05	195	151	6	0e55fa5b3cbeb7baee3d4ac272a3bf80381ec937
ToppCell	LA-02._Fibroblast_II\|World / Chamber and Cluster_Paper	PDE3B COL15A1 AOX1 EBF1 PXDN HMCN2	5.43e-05	195	151	6	a78b605b49acd8c9d68716266ca269dafcd910b9
ToppCell	proximal-3-Endothelial-Capillary_Aerocyte\|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	PCDHGB5 LGR5 RASIP1 MFNG ADGRL2 FOXF1	5.43e-05	195	151	6	36b2e754ed7ff138ac05fb51f4494e5339669828
ToppCell	facs-Lung-ENDOMUCIN-18m-Endothelial-Capillary_Aerocyte_endothelial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLC22A23 PPHLN1 RASIP1 MFNG ADGRL2 FOXF1	5.43e-05	195	151	6	cad21edd90bf3e2fefdf5773a59cb1a664a69ddd
ToppCell	15-Trachea-Mesenchymal\|Trachea / Age, Tissue, Lineage and Cell class	NID2 COL15A1 MMP23B EBF1 ANGPTL1 FOXF1	5.58e-05	196	151	6	7e178c76285e61c721c38d7a995ebf89dc428f9f
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	COL15A1 SPEG EBF1 HIF3A CPED1 HMCN2	5.58e-05	196	151	6	1522958a92e0126326a9f0d9fb1c5b5c50b001ea
ToppCell	Bronchial-NucSeq-Stromal-Mesofibroblastic\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	NID2 CALB2 AOX1 MUC16 PPOX DNAH9	5.58e-05	196	151	6	96e5c6d155273e82ebafa180df8bb589c3e3e54e
ToppCell	PBMC-Severe-Lymphocyte-T/NK-Other_T-gd_T\|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)	RBL2 CHD3 ERBIN ZNF600 LLGL2 ATM	5.58e-05	196	151	6	418e8e0a51c5cb60e3b903e7d2d800dc8b9f3d5c
ToppCell	COVID-19-lung-Capillary_Aerocytes\|COVID-19 / Disease (COVID-19 only), tissue and cell type	PDE3B HIF3A RASIP1 PXDN ADGRL2 FOXF1	5.58e-05	196	151	6	49cc0a2b9739abad61dff7292ea0b14d28ff35c4
ToppCell	PBMC-Severe-Lymphocyte-T/NK-Other_T-gd_T-\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	RBL2 CHD3 ERBIN ZNF600 LLGL2 ATM	5.58e-05	196	151	6	581fc8c8d42005aacd7b401a2c9d1fc331fb4af7
ToppCell	Control-Stromal-Fibroblast\|Control / Disease state, Lineage and Cell class	CADM3 AOX1 MMP23B EBF1 ANGPTL1 PXDN	5.58e-05	196	151	6	7ca94477498a84cafcdd9933ee92a6cbde76c70e
ToppCell	Bronchial-NucSeq-Stromal-Mesofibroblastic-Mesothelia\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	NID2 CALB2 AOX1 MUC16 PPOX DNAH9	5.58e-05	196	151	6	ce13af36fc2932e8125013041742593ff3d07e86
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast-\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	COL15A1 SPEG EBF1 HIF3A CPED1 HMCN2	5.58e-05	196	151	6	1c8294014713684b50885e638668f2ce75f357f0
ToppCell	PBMC-Severe-Lymphocyte-T/NK-Other_T-gd_T-\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	RBL2 CHD3 ERBIN ZNF600 LLGL2 ATM	5.58e-05	196	151	6	6beaf0c2799424c59819b286fbb5c1a83d85e4d1
ToppCell	NS-control-d_0-4-Epithelial-Ciliated\|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	TMEM67 EFHB PPOX CC2D2A DNAH9 HYDIN	5.58e-05	196	151	6	d46ab80554dd3c1cc81e1938ea2acfd5e85c6d2a
ToppCell	PBMC-Severe-Lymphocyte-T/NK-Other_T-gd_T\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	RBL2 CHD3 ERBIN ZNF600 LLGL2 ATM	5.58e-05	196	151	6	c35f2349dfe35baa845f790b9f31673dceac54c0
ToppCell	15-Trachea-Mesenchymal-Mesenchyme_SERPINF1-high\|Trachea / Age, Tissue, Lineage and Cell class	NID2 COL15A1 MMP23B EBF1 ANGPTL1 FOXF1	5.58e-05	196	151	6	54aefcebf13704f51de84379e2e22ec0734b9461
ToppCell	COVID-19-lung-Capillary_Aerocytes\|lung / Disease (COVID-19 only), tissue and cell type	PDE3B HIF3A RASIP1 PXDN ADGRL2 FOXF1	5.58e-05	196	151	6	4ac4073380d939a73cec7413e9f3f5ef616d2924
ToppCell	proximal-Endothelial-Capillary-3\|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	PDE3B RASIP1 SP6 ADGRL2 FOXF1 MOV10	5.74e-05	197	151	6	ddb8ea895f0f34d4f20a0740b708fa0f3e378801
ToppCell	5'-Airway_Nasal-Epithelial-Airway_ciliated\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	IFT172 MUC16 EFHB CC2D2A DNAH9 HYDIN	5.74e-05	197	151	6	91637bdeab85024b5a02d1066f76cb803a2d6420
ToppCell	proximal-Endothelial-Capillary\|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	PDE3B RASIP1 SP6 ADGRL2 FOXF1 MOV10	5.74e-05	197	151	6	53baef54bd85c60ae24a3c163b3a3d937fb6ff0b
ToppCell	control-Epithelial-Ciliated\|Epithelial / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	TMEM67 EFHB PPOX CC2D2A DNAH9 HYDIN	5.74e-05	197	151	6	e453d085182364ca347cbcc9dc995c62c3353016
ToppCell	proximal-3-Endothelial-Capillary\|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	PDE3B RASIP1 SP6 ADGRL2 FOXF1 MOV10	5.74e-05	197	151	6	a1a61c03d67272693ec23e0d15f0a12bf618e2da
ToppCell	control-Epithelial-Ciliated\|control / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	TMEM67 EFHB PPOX CC2D2A DNAH9 HYDIN	5.74e-05	197	151	6	d4e963c1f82996371bf3d63578ee9fce8e00c5a8
ToppCell	Brain_organoid-organoid_Kanton_Nature-Organoid-2M-IPC_like\|Organoid-2M / Sample Type, Dataset, Time_group, and Cell type.	SLC22A23 CHD3 MFNG DLL3 DISP3 DOP1B	5.91e-05	198	151	6	6d12ecaa9532c134d9c4562534dcb59a6420b4d3
ToppCell	Brain_organoid-organoid_Kanton_Nature-Organoid-2M-IPC_like-IPs_and_early_cortical_neurons\|Organoid-2M / Sample Type, Dataset, Time_group, and Cell type.	SLC22A23 CHD3 MFNG DLL3 DISP3 DOP1B	5.91e-05	198	151	6	7943e4f67c3d6efb5c8b00aa0ff3cfe7be10c48d
ToppCell	Control-Stromal\|Control / Disease state, Lineage and Cell class	CADM3 AOX1 MMP23B EBF1 ANGPTL1 PXDN	5.91e-05	198	151	6	ae726b6b7f0a4107899be4d32ac256ffa0bd8d59
Disease	Colorectal Carcinoma	RELCH LGR5 ADARB2 DSCAML1 PPOX TYMS LIG1 P2RX7 SACS KLF5 MTRR KDM6A PHIP JPH3 SORL1	2.70e-06	702	148	15	C0009402
Disease	Neoplasm of uncertain or unknown behavior of bladder	ATM KDM6A NOTCH1	5.38e-05	15	148	3	C0496930
Disease	Benign neoplasm of bladder	ATM KDM6A NOTCH1	5.38e-05	15	148	3	C0154017
Disease	Carcinoma in situ of bladder	ATM KDM6A NOTCH1	5.38e-05	15	148	3	C0154091
Disease	cancer (implicated_via_orthology)	RBL2 HIF3A LIG1 PHC3 LLGL2 ATM ALK NOTCH1	6.57e-05	268	148	8	DOID:162 (implicated_via_orthology)
Disease	COACH syndrome	TMEM67 CC2D2A	7.47e-05	3	148	2	cv:C1857662
Disease	Hepatic Fibrosis, Congenital	TMEM67 CC2D2A	7.47e-05	3	148	2	C0009714
Disease	amelogenesis imperfecta (is_implicated_in)	FAM20C SP6	7.47e-05	3	148	2	DOID:2187 (is_implicated_in)
Disease	Carcinoma of bladder	ATM KDM6A NOTCH1	9.55e-05	18	148	3	C0699885
Disease	COACH syndrome	TMEM67 CC2D2A	1.49e-04	4	148	2	C1857662
Disease	chronic obstructive pulmonary disease, interleukin-8 measurement	P2RX7 HYDIN	1.49e-04	4	148	2	EFO_0000341, EFO_0004811
Disease	creatinine measurement	ATP6V1B1 SPEG R3HDM2 ADARB2 BRWD3 RASIP1 PRRC2C NFKB1 SP6 PCDHGB4 FAM47E MBD5 ADGRL2 ABCC10 SORL1	1.51e-04	995	148	15	EFO_0004518
Disease	Adenoid Cystic Carcinoma	ERBIN MAGI2 ATM KDM6A NOTCH1	1.52e-04	100	148	5	C0010606
Disease	Chronic Lymphocytic Leukemia	RBL2 XPO1 P2RX7 ATM	1.70e-04	55	148	4	C0023434
Disease	testosterone measurement	DIP2B ARSJ PNMA6E MARS1 FAXC ARHGAP9 R3HDM2 EBF1 ADAR NFKB1 MCM9 FAM47E ADGRL2 PHIP ARHGAP21 MED12 ABCC10	2.34e-04	1275	148	17	EFO_0004908
Disease	neuroblastoma (implicated_via_orthology)	LLGL2 ALK	2.47e-04	5	148	2	DOID:769 (implicated_via_orthology)
Disease	Prostatic Neoplasms	COL15A1 AOX1 NDST2 CHD3 XPO1 TYMS AAAS TLR5 ATM KDM6A MED12	2.91e-04	616	148	11	C0033578
Disease	Malignant neoplasm of prostate	COL15A1 AOX1 NDST2 CHD3 XPO1 TYMS AAAS TLR5 ATM KDM6A MED12	2.91e-04	616	148	11	C0376358
Disease	Polydactyly	TMEM67 FRAS1 IFT172 TFAP2A CC2D2A	3.17e-04	117	148	5	C0152427
Disease	Alcoholic Intoxication, Chronic	CDK20 UBAP2 CLOCK DSCAML1 AGO1 NFKB1 ALK	4.24e-04	268	148	7	C0001973
Disease	childhood trauma measurement, alcohol consumption measurement	PCDHGC4 PCDHGB5 SIM2 PCDHGB4	4.55e-04	71	148	4	EFO_0007878, EFO_0007979
Disease	serum urea measurement	R3HDM2 EBF1 PCDHGB4 ADGRL2 ABCC10 SORL1	4.67e-04	195	148	6	EFO_0009795
Disease	blood urea nitrogen measurement	PPHLN1 R3HDM2 EBF1 TRMU PCDHGB4 MBD5 ADGRL2 ABCC10 SORL1	4.82e-04	452	148	9	EFO_0004741
Disease	birth measurement, spontaneous preterm birth	ADGRL2 SORL1	5.16e-04	7	148	2	EFO_0006917, EFO_0006921
Disease	Hyperammonemia	TYMS TLR5	5.16e-04	7	148	2	C0220994
Disease	alkaline phosphatase measurement	RBL2 CHD3 EBF1 TRIM6 PRAG1 RASIP1 AAAS YKT6 P2RX7 TONSL FAM47E ARHGAP21 NOTCH1 ABCC10	6.11e-04	1015	148	14	EFO_0004533
Disease	Scoliosis, unspecified	DLL3 NOTCH1	6.86e-04	8	148	2	C0036439
Disease	Meckel syndrome (implicated_via_orthology)	TMEM67 CC2D2A	6.86e-04	8	148	2	DOID:0050778 (implicated_via_orthology)
Disease	lung non-small cell carcinoma (is_implicated_in)	XPO1 NFKB1 ATM KDM6A BAG6	6.96e-04	139	148	5	DOID:3908 (is_implicated_in)
Disease	Neoplastic Cell Transformation	EBF1 NFKB1 SUV39H1 ALK NOTCH1	6.96e-04	139	148	5	C0007621
Disease	Bladder Neoplasm	LIG1 KLF5 ATM KDM6A NOTCH1	7.19e-04	140	148	5	C0005695
Disease	mean reticulocyte volume	FNTB XPO1 CPED1 ME3 TYMS NFKB1 TONSL CC2D2A ATM BAG6 ARHGAP21 ABCC10	7.27e-04	799	148	12	EFO_0010701
Disease	Malignant neoplasm of urinary bladder	LIG1 KLF5 ATM KDM6A NOTCH1	7.42e-04	141	148	5	C0005684
Disease	visceral heterotaxy (implicated_via_orthology)	TMEM67 MTRR CC2D2A	8.48e-04	37	148	3	DOID:0050545 (implicated_via_orthology)
Disease	Nephronophthisis	TMEM67 IFT172	8.79e-04	9	148	2	cv:C0687120
Disease	Malignant neoplasm of breast	NID2 UTS2R ZSWIM5 PPHLN1 ADAR TFAP2A TYMS LLGL2 ATM DNAH9 ALK MED12 NOTCH1 SORL1	1.05e-03	1074	148	14	C0006142
Disease	Inherited neuropathies	SACS WASHC5 ATM	1.07e-03	40	148	3	C0598589
Disease	Meckel-Gruber syndrome	TMEM67 CC2D2A	1.10e-03	10	148	2	cv:C0265215
Disease	cystic kidney disease (implicated_via_orthology)	TMEM67 IFT172	1.10e-03	10	148	2	DOID:2975 (implicated_via_orthology)
Disease	Small Lymphocytic Lymphoma	P2RX7 ATM	1.10e-03	10	148	2	C0855095
Disease	B-CELL MALIGNANCY, LOW-GRADE	P2RX7 ATM	1.10e-03	10	148	2	C1868683
Disease	Congenital small ears	FRAS1 TFAP2A KDM6A	1.15e-03	41	148	3	C0152423
Disease	interleukin 2 measurement	EBF1 CPED1 ADARB2	1.15e-03	41	148	3	EFO_0008331
Disease	Congenital Abnormality	DLL3 NOTCH1	1.33e-03	11	148	2	C0000768
Disease	Macrocephaly	CHD3 BRWD3	1.33e-03	11	148	2	C0221355
Disease	sleep disorder (implicated_via_orthology)	CLOCK TFAP2A	1.33e-03	11	148	2	DOID:535 (implicated_via_orthology)
Disease	Mammary Carcinoma, Human	ZSWIM5 ADAR TFAP2A TYMS LLGL2 ATM ALK MED12 NOTCH1	1.38e-03	525	148	9	C4704874
Disease	Mammary Neoplasms, Human	ZSWIM5 ADAR TFAP2A TYMS LLGL2 ATM ALK MED12 NOTCH1	1.38e-03	525	148	9	C1257931
Disease	Mammary Neoplasms	ZSWIM5 ADAR TFAP2A TYMS LLGL2 ATM ALK MED12 NOTCH1	1.42e-03	527	148	9	C1458155
Disease	triglyceride measurement, alcohol drinking	R3HDM2 EBF1 NFE2L3 SP6	1.58e-03	99	148	4	EFO_0004329, EFO_0004530
Disease	Breast Carcinoma	ZSWIM5 ADAR TFAP2A TYMS LLGL2 ATM ALK MED12 NOTCH1	1.63e-03	538	148	9	C0678222
Disease	triglyceride measurement, alcohol consumption measurement	R3HDM2 EBF1 NFE2L3 SP6	1.70e-03	101	148	4	EFO_0004530, EFO_0007878
Disease	Gastrointestinal Stromal Sarcoma	IFT172 CC2D2A FOXF1	1.71e-03	47	148	3	C3179349
Disease	Bardet-Biedl Syndrome	TMEM67 IFT172	1.88e-03	13	148	2	C0752166
Disease	Gastrointestinal Stromal Tumors	IFT172 CC2D2A FOXF1	2.04e-03	50	148	3	C0238198
Disease	superior frontal gyrus grey matter volume measurement	TBC1D19 NFE2L3	2.19e-03	14	148	2	EFO_0006516
Disease	hepatocellular carcinoma (is_implicated_in)	XPO1 TYMS NFKB1 MTRR KDM6A	2.24e-03	181	148	5	DOID:684 (is_implicated_in)
Disease	amino acid measurement	UTP6 ARHGAP9 ADARB2 LIG1 PXDN MCM9 SCN4A ADGRL2 ALK NOTCH1	2.29e-03	678	148	10	EFO_0005134
Disease	nervous system disorder	TYMS MTRR NOTCH1	2.41e-03	53	148	3	C0027765
Disease	Meckel-Gruber syndrome	TMEM67 CC2D2A	2.51e-03	15	148	2	C0265215
Disease	Down syndrome (implicated_via_orthology)	DSCAML1 DOP1B	2.51e-03	15	148	2	DOID:14250 (implicated_via_orthology)
Disease	Lymphoma, Follicular, Grade 2	EBF1 TYMS	2.51e-03	15	148	2	C1956132
Disease	Lymphoma, Follicular, Grade 3	EBF1 TYMS	2.51e-03	15	148	2	C1956131
Disease	Lymphoma, Follicular, Grade 1	EBF1 TYMS	2.51e-03	15	148	2	C1956130
Disease	Lymphoma, Large-Cell, Follicular	EBF1 TYMS	2.51e-03	15	148	2	C0079745
Disease	Lymphoma, Small Cleaved-Cell, Follicular	EBF1 TYMS	2.51e-03	15	148	2	C0079765
Disease	Lymphoma, Mixed-Cell, Follicular	EBF1 TYMS	2.51e-03	15	148	2	C0079758
Disease	acute lymphoblastic leukemia (is_implicated_in)	TYMS MTRR KDM6A	2.68e-03	55	148	3	DOID:9952 (is_implicated_in)
Disease	Colorectal Neoplasms	LGR5 PPOX TYMS KLF5 MTRR JPH3	2.81e-03	277	148	6	C0009404
Disease	vision disorder	MAGI2 PXDN	2.86e-03	16	148	2	MONDO_0021084
Disease	Malignant lymphoma, lymphocytic, intermediate differentiation, diffuse	ATM NOTCH1	2.86e-03	16	148	2	C0334634
Disease	free androgen index	R3HDM2 ADAR MCM9 FAM47E PHIP ARHGAP21 ABCC10	2.89e-03	374	148	7	EFO_0007005
Disease	glycoprotein measurement	R3HDM2 PRAG1 ARHGAP21 HYDIN	3.09e-03	119	148	4	EFO_0004555
Disease	pre-malignant neoplasm (biomarker_via_orthology)	SUV39H1 ATM	3.23e-03	17	148	2	DOID:0060071 (biomarker_via_orthology)
Disease	Squamous cell carcinoma	TYMS KLF5 ATM NOTCH1	3.58e-03	124	148	4	C0007137
Disease	Meckel syndrome type 1	TMEM67 CC2D2A	3.63e-03	18	148	2	C3714506
Disease	hydrocephalus (implicated_via_orthology)	TMEM67 HYDIN	4.04e-03	19	148	2	DOID:10908 (implicated_via_orthology)
Disease	Familial aplasia of the vermis	TMEM67 CC2D2A	4.47e-03	20	148	2	cv:C0431399
Disease	Lymphoma, Follicular	EBF1 TYMS	4.47e-03	20	148	2	C0024301
Disease	non-word reading	ADARB2 PCDHGB4 SORL1	4.68e-03	67	148	3	EFO_0005299
Disease	retinal vasculature measurement	ARHGAP9 PRAG1 ADARB2 DSCAML1 LUZP1 RASIP1 PXDN DNAH9	4.69e-03	517	148	8	EFO_0010554
Disease	haptoglobin measurement	CALB2 HYDIN	4.93e-03	21	148	2	EFO_0004640

Protein segments in the cluster

Peptide	Gene	Start	Entry
QPTHPIRLGLALNYS	YWHAG	166	P61981
PANHVLVNQYLPGEG	ALKBH6	96	Q3KRA9
LNIVHATQLYRRGPP	CXCR3	151	P49682
GQPLRPQANYSQIHH	ERBIN	1261	Q96RT1
PPRGQVTLYEHNNEL	AAAS	11	Q9NRG9
GQFLLYPPHQRIAAS	CDK20	266	Q8IZL9
VEGYLLAGENLPPHQ	DISP3	1256	Q9P2K9
IRIVDLNNHPPTFYG	CDHR1	341	Q96JP9
NFRSPYHVRGPINQV	CPED1	996	A4D0V7
QHYLGGQEPTPSNIR	BAG6	791	P46379
VLLLVHNLPQDPRGY	CEACAM8	51	P31997
SLLDPHIYRVTNFPQ	GVINP1	596	Q7Z2Y8
RDGVPEGQLPQILHY	AGO1	666	Q9UL18
VNDPYSLNPLHAQPQ	TFAP2A	76	P05549
GDVPHLPVNRAYSVN	BRWD3	666	Q6RI45
RQPADLLSYPGHQEQ	BRWD3	1326	Q6RI45
YLLTNPLLRPHGTNN	ADGRL2	1171	O95490
PLLRPHGTNNPYNTL	ADGRL2	1176	O95490
QHIPNSQQYTPGLLG	ANGPTL1	221	O95841
GQRQHLLFPYPSSIL	DLL3	601	Q9NYJ7
LLHCEGRGNPVPQQY	CADM3	251	Q8N126
NYSPQGILHTRGPDQ	AOX1	1221	Q06278
PRQPNHYLQALRAVG	CPNE6	331	O95741
QLTPGVVYVRHLPNL	NIFK	41	Q9BYG3
LSHPVAYSPQRGQQL	R3HDM2	536	Q9Y2K5
QQELPANYRHGPPVA	RASIP1	946	Q5U651
FGVQQLHPALIQRPF	RBM24	101	Q9BX46
VGQLPASYRHNRPLL	ADARB2	606	Q9NS39
QRLPHSQPQLQELQY	IQCC	151	Q4KMZ1
LSARYGPQFTLQHVP	PCDHGB4	866	Q9UN71
GPQFTLQHVPDYRQN	PCDHGB4	871	Q9UN71
RRIQLSQNHPVYISP	RBL2	1046	Q08999
DVHSGYDIPLNPLNL	MSMO1	226	Q15800
PPDLLQLYRDFGNHQ	RELCH	301	Q9P260
ILHQFARPNNGVPSL	FAXC	101	Q5TGI0
HLNPQSPGLDREQLY	MUC16	13086	Q8WXI7
IQLFLDLPNHNPQAY	ABCC10	571	Q5T3U5
IPRGPVLHRNNIADY	MDN1	1711	Q9NU22
YNLVRSPQLHGAPLG	NOTCH1	2116	P46531
IVYNITLPLHPNQGI	FRAS1	1501	Q86XX4
PYFPQILNRTSQHLV	MAGEB6	231	Q8N7X4
PPQPLQLQGHENSYR	MAGI2	1056	Q86UL8
EHPRDPNQILIGYSR	LLGL2	196	Q6P1M3
AAQYRQQARHPLILP	NUDT18	166	Q6ZVK8
YLQPRPGHFISIEDN	TRMU	236	O75648
YNAARGPQPQLVQHL	HMCN2	4566	Q8NDA2
PYEEHGLILPNGNIN	CHCHD4	36	Q8N4Q1
QAVHSPLQAPGRYFE	ARSJ	266	Q5FYB0
QYVQPHPLTSQGLLV	DOP1B	1486	Q9Y3R5
QQRRKDPEGTPYINH	HDDC3	21	Q8N4P3
PPEYLQVHLQESLGQ	MTRR	246	Q9UBK8
NVPYLQRNALTLPHN	KDM6A	606	O15550
EYLNRSLIPHQIPGN	PNMA6E	71	A0A0J9YXQ4
QYQQHRPSLEGGRSP	PNRC1	116	Q12796
YLTTRPVPGLQQIHN	PDE3B	751	Q13370
AVNQEVSDHGLPYLP	LPO	331	P22079
DDQGRPVNPNHYALQ	NFE2L3	651	Q9Y4A8
GHLNAGDNVVLLYPP	DIP2B	1041	Q9P265
LQQRPSGYVHQQAPT	MED12	1991	Q93074
HLEFLGQLRQYDPPA	KLC3	146	Q6P597
LSHGQNPLPIYCALN	PLA2G4B	426	P0C869
LSARYGPQFTLQHVP	PCDHGB5	866	Q9Y5G0
GPQFTLQHVPDYRQN	PCDHGB5	871	Q9Y5G0
LSARYGPQFTLQHVP	PCDHGC4	881	Q9Y5F7
GPQFTLQHVPDYRQN	PCDHGC4	886	Q9Y5F7
LPSIGRLSQYQEPLH	PCCA	411	P05165
RLSQYQEPLHLPGVR	PCCA	416	P05165
APLLQTSAHQYLAPR	NUDT13	56	Q86X67
QQALHRPPSSAAQYL	PHC3	51	Q8NDX5
PARTQGTPVHLNYRQ	MAN1B1	236	Q9UKM7
IVHFNLYPQPGRRDV	MAN1B1	571	Q9UKM7
QALALYVQHGAPANP	IFT172	1461	Q9UG01
NDGRAYTAISHIPQP	NID2	561	Q14112
IDFPGHNYTTRNILP	P2RX7	196	Q99572
QLLPQQRHGERTPYV	ATM	441	Q13315
RPVLHNQYGNPLLLF	HYDIN	3481	Q4G0P3
PTHNADYPLGQVLVR	CC2D2A	1086	Q9P2K1
EHRQLRYQQPGPGSS	ADAR	21	P55265
NPQQYHPVPLTGRIQ	DSCAML1	731	Q8TD84
GDQVAPVLYQPHLEA	FAM20C	531	Q8IXL6
RRAAYLNLSQEPAHP	CHD3	1811	Q12873
QQLRLTQYHGGSLPN	CRTC3	51	Q6UUV7
APVLYLEGRQHPIQV	DHX33	246	Q9H6R0
LYSVPRNHNQLPALA	EBF1	411	Q9UH73
YRQLHNSLDPSELPG	LUZP1	1036	Q86V48
EQHLSQGRLYPPLST	ME3	526	Q16798
QQELHPVYPRQRLGS	MBD5	191	Q9P267
RANDPQIAPYLTHGI	EFHB	311	Q8N7U6
ENALQPTHPVYNIGP	FNTB	391	P49356
QQPPYLHLAELTASQ	CALB2	6	P22676
QSYLHLVGVPQPEGQ	CYP39A1	446	Q9NYL5
LSPQNGSPHYQVDLD	DNAH9	966	Q9NYC9
ALYSVPRNHNQIPTL	EBF3	411	Q9H4W6
GPPLDLAYLRHFLNN	COL15A1	1011	P39059
LYLSLNHLGPPQQGL	LIG1	331	P18858
FHPQYQEVNGTLPLI	SACS	3666	Q9NZJ4
SHPSDGYNRLVNIVP	PPHLN1	21	Q8NEY8
RHLPSGPERYQALLQ	CCDC103	111	Q8IW40
HPQRGYLPVQSVLEA	DRP2	686	Q13474
YHLNLSPQRVQGTPE	MFNG	26	O00587
QSLRLDANHISYVPP	LGR5	141	O75473
SVHLVPNTINGNIYP	TMEM67	471	Q5HYA8
LHTSFPENPGEQYQR	MCM9	616	Q9NXL9
APAELQGIPRYHSQS	FOXF1	321	Q12946
LQFLGHPILNDPIYN	RPUSD2	376	Q8IZ73
PQEGHLPALRQNRYL	RTL1	1206	A6NKG5
AQHGPYIRDDPALQF	RSPH6A	161	Q9H0K4
VEGFLPQIYHRAPQL	FAM47E	71	Q6ZV65
DINGQPINPHSRIYP	ATP6V1B1	146	P15313
LNHPLGRPENCGQIY	UTP6	556	Q9NYH9
QQRSVILDNLPHPYA	SORL1	951	Q92673
HLNFINNPYLTIQVP	SCN4A	911	P35499
NYRSHPTILDIPNQL	MOV10	731	Q9HCE1
QPSDLRIGFYPINHT	MMP23B	136	O75900
LPENISNGEHYTRQP	SLC22A23	626	A1A5C7
VLLLVHNLPQNLPGY	PSG9	51	Q00887
QALPPLFSLGYHQSR	GANAB	386	Q14697
QLNASEQLPRAYHRP	HIF3A	501	Q9Y2N7
RHAAQLVPSNGQPYN	SMG7	176	Q92540
IPIYAPLQGQHQAQL	PRRC2C	2431	Q9Y520
TQPIPILYEHQLGQA	PRRC2C	2516	Q9Y520
APAQLPFVLLNYHRV	SIM2	591	Q14190
HPQLSPRQSLETQYL	SIK2	666	Q9H0K1
EYDFHLLPSGIINPN	ADSS2	76	P30520
PPRLDLQPLQTYQGH	SP6	21	Q3SY56
TPRHLDPSLANYLVQ	SUV39H1	106	O43463
VPNLGPAEQEQNHYL	SLC39A5	26	Q6ZMH5
QPSGRYIAQLLPHNE	ALK	356	Q9UM73
GQLQLYRHPDRSQPA	ATF6B	566	Q99941
PPQQFLQTSRLLHGN	CLOCK	781	O15516
ALGNHQPLPYIERFT	C10orf120	176	Q5SQS8
PALDGHLSRYQNPRE	YKT6	121	O15498
NPPQISEIFQGYHQR	PRY	81	O14603
PVRGDHPAAQNRFLY	PPOX	86	P50336
QPQPLGPYLRSLSQH	LINC00173	76	Q6ZV60
GSQHFDVPPRRQLYL	XPO1	396	O14980
NLPQGVPPLLHNQYL	UBAP2	796	Q5T6F2
GNYGHELPNITNALP	ZSWIM5	456	Q9P217
YPLPEHRSTALANQA	WASHC5	241	Q12768
VDVDGNPHPSRYQRL	PHIP	591	Q8WWQ0
SAQPYNPQALRPLGH	SPEG	3106	Q15772
QDLVRQGHPLNPRDY	TONSL	546	Q96HA7
PASYHQPEGVARILN	SOGA1	1321	O94964
AINIQRGRDHGIPPY	PXDN	1156	Q92626
PPHGELQYLGQIQHI	TYMS	26	P04818
GLRDYQVNPSAPLLH	NDST2	196	P52849
DPAAHALYPGQLVQL	ARHGAP9	726	Q9BRR9
QTGILIYELLHQPNP	PRAG1	1256	Q86YV5
AQYHQAPLAPRTARI	UTS2R	281	Q9UKP6
VLYLNHNYLNSLPPG	TLR5	506	O60602
RISPRPQIHISNNYG	ZNF600	126	Q6ZNG1
QTPQPLRHQSYILAV	ARHGAP21	746	Q5T5U3
LPQLFYHLREIGAQP	TBC1D19	426	Q8N5T2
IVAYGNLHPQPLQDS	TRIM62	316	Q9BVG3
ALPYVNNVPHLGNII	MARS1	271	P56192
GNLHYLQTGRLSQDP	SIT1	91	Q9Y3P8
TSYQPGNLRPNRHLA	TRIM6	61	Q9C030
VPTQQGHLYQLLNTP	KLF5	221	Q13887
PSFQHRENGLEYQRP	JPH3	421	Q8WXH2
NGIRVAPVPLYNSFH	KYNU	431	Q16719
NPGLLVHPDLAYLQA	NFKB1	166	P19838