Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionmicrotubule binding

CEP290 KIF20B KIF7 CCDC88A HOOK3 CDK5RAP2 MACF1 CEP295 ARHGEF2 KIF17

1.48e-0530811810GO:0008017
GeneOntologyMolecularFunctionsmall GTPase binding

TNPO1 ROCK2 DOCK3 SIKE1 IQGAP1 MICALL1 GCC2 RNF41 ARHGEF2 GOLGA4

2.11e-0532111810GO:0031267
GeneOntologyMolecularFunctiontubulin binding

TPR CEP290 KIF20B KIF7 CCDC88A HOOK3 CDK5RAP2 MACF1 CEP295 ARHGEF2 KIF17

4.72e-0542811811GO:0015631
GeneOntologyMolecularFunctionmitogen-activated protein kinase binding

TPR ATF7 IQGAP1 NBR1

5.27e-05351184GO:0051019
GeneOntologyMolecularFunctionGTPase binding

TNPO1 ROCK2 DOCK3 SIKE1 IQGAP1 MICALL1 GCC2 RNF41 ARHGEF2 GOLGA4

5.56e-0536011810GO:0051020
GeneOntologyMolecularFunctionvascular endothelial growth factor receptor binding

ANGPT1 ANGPT2 CCDC88A

1.29e-04171183GO:0005172
GeneOntologyMolecularFunctionprotein kinase binding

TPR ATF7 SIKE1 ANGPT1 ANGPT2 E2F1 NBEA TRIM34 UFL1 IQGAP1 SLC12A5 CCDC88A CDK5RAP2 RNF41 NBR1

1.96e-0487311815GO:0019901
GeneOntologyMolecularFunctioncytoskeletal protein binding

ROCK2 TPR SYNE1 SPTBN2 CEP290 KIF20B IQGAP1 KIF7 BLOC1S6 CCDC88A HOOK3 CDK5RAP2 MACF1 CEP295 ARHGEF2 CROCC KIF17

2.50e-04109911817GO:0008092
GeneOntologyMolecularFunctionkinase binding

TPR ATF7 SIKE1 ANGPT1 ANGPT2 E2F1 NBEA TRIM34 UFL1 IQGAP1 SLC12A5 CCDC88A CDK5RAP2 RNF41 NBR1

5.90e-0496911815GO:0019900
GeneOntologyBiologicalProcessmicrotubule-based process

ROCK2 TPR CEP290 APOB DZIP1 CNTROB KIF20B KIF7 FSIP2 BLOC1S6 CCDC88A HOOK3 GCC2 CEP250 NAV1 CDK5RAP2 MACF1 CEP295 CFAP57 ARHGEF2 CROCC SPAG17 KIF17

2.79e-08105811823GO:0007017
GeneOntologyBiologicalProcessmicrotubule cytoskeleton organization

ROCK2 TPR CEP290 DZIP1 CNTROB FSIP2 CCDC88A HOOK3 GCC2 CEP250 NAV1 CDK5RAP2 CEP295 CFAP57 ARHGEF2 CROCC SPAG17

7.31e-0772011817GO:0000226
GeneOntologyBiologicalProcesscilium organization

SYNE1 CEP290 DZIP1 CNTROB CEP164 FSIP2 BLOC1S6 CCDC88A CEP250 CFAP57 CROCC SPAG17 KIF17

3.44e-0647611813GO:0044782
GeneOntologyBiologicalProcessregulation of organelle assembly

TPR SYNE1 SPTBN2 DZIP1 CNTROB CCDC88A CDK5RAP2 CEP295 ARHGEF2 CROCC

4.86e-0628011810GO:1902115
GeneOntologyBiologicalProcesspositive regulation of protein localization to cilium

DZIP1 CCDC88A CROCC

6.28e-0671183GO:1903566
GeneOntologyBiologicalProcessmicrotubule organizing center organization

ROCK2 DZIP1 CNTROB GCC2 CEP250 CDK5RAP2 CEP295 CROCC

8.93e-061791188GO:0031023
GeneOntologyBiologicalProcesscilium assembly

SYNE1 CEP290 DZIP1 CNTROB CEP164 FSIP2 BLOC1S6 CCDC88A CEP250 CFAP57 CROCC SPAG17

9.28e-0644411812GO:0060271
GeneOntologyBiologicalProcessorganelle assembly

TPR SYNE1 SPTBN2 CEP290 FASTKD2 DZIP1 CNTROB CEP164 FSIP2 BLOC1S6 CCDC88A CEP250 CDK5RAP2 CEP295 CFAP57 ARHGEF2 CROCC SPAG17 VPS13B

2.41e-05113811819GO:0070925
GeneOntologyBiologicalProcessregulation of protein localization to cilium

DZIP1 CCDC88A CROCC

2.91e-05111183GO:1903564
GeneOntologyBiologicalProcessslow endocytic recycling

MICALL1 VPS13B

3.25e-0521182GO:0032458
GeneOntologyBiologicalProcessprotein localization to organelle

TNPO1 ROCK2 TPR ANGPT1 SYNE1 NBEA DZIP1 TEX15 KIF20B MICALL1 FSIP2 VPS13D CCDC88A HOOK3 GCC2 CEP250 MACF1 CROCC

4.73e-05109111818GO:0033365
GeneOntologyBiologicalProcessintracellular transport

TNPO1 DDX19B TPR CCHCR1 ANGPT1 SYNE1 CEP290 KIF20B MICALL1 BLOC1S6 VPS13D CCDC88A HOOK3 GCC2 SNX8 ARHGEF2 SPAG17 KIF17 VPS13B DOP1B CREB3L2

1.08e-04149611821GO:0046907
GeneOntologyBiologicalProcesscanonical NF-kappaB signal transduction

ROCK2 DHX36 TRAF1 TANK ANGPT1 TRIM34 UFL1 TLR3 FLOT1

1.19e-043301189GO:0007249
GeneOntologyBiologicalProcessneuron projection development

ROCK2 DHX36 PLEKHG4 SYNE1 CDH23 KIF20B MFN1 IQGAP1 SLC12A5 MICALL1 ARHGAP4 BLOC1S6 CCDC88A TENM3 MACF1 FLOT1 VPS13B GOLGA4 CREB3L2

1.23e-04128511819GO:0031175
GeneOntologyBiologicalProcessregulation of protein localization

ROCK2 TPR ANGPT1 CEP290 NBEA TRIM34 UFL1 DZIP1 TEX15 IDUA KIF20B IQGAP1 CCDC88A GCC2 CEP250 CEP295 CROCC

1.50e-04108711817GO:0032880
GeneOntologyBiologicalProcessregulation of cellular localization

ROCK2 TPR DHX36 ANGPT1 CEP290 NBEA TRIM34 UFL1 DZIP1 TEX15 IDUA KIF20B IQGAP1 CCDC88A GCC2 CEP250 CEP295 CROCC

1.79e-04121211818GO:0060341
GeneOntologyBiologicalProcessnuclear matrix organization

TPR SYNE1

1.93e-0441182GO:0043578
GeneOntologyBiologicalProcessregulation of organelle organization

ROCK2 TPR DHX36 EXOSC10 SYNE1 SPTBN2 UFL1 DZIP1 CNTROB KIF20B MFN1 VPS13D CCDC88A VAMP1 CDK5RAP2 RNF41 CEP295 ARHGEF2 CROCC

2.15e-04134211819GO:0033043
GeneOntologyBiologicalProcessneuron development

ROCK2 DHX36 PLEKHG4 SYNE1 CEP290 CDH23 KIF20B MFN1 IQGAP1 SLC12A5 MICALL1 ARHGAP4 BLOC1S6 CCDC88A TENM3 MACF1 FLOT1 VPS13B GOLGA4 CREB3L2

2.29e-04146311820GO:0048666
GeneOntologyBiologicalProcesspositive regulation of cellular component organization

ROCK2 TPR DHX36 ANGPT1 SYNE1 UFL1 DZIP1 MFN1 IQGAP1 VPS13D CCDC88A TENM3 CDK5RAP2 MACF1 CEP295 CROCC FLOT1 GOLGA4 CREB3L2

2.69e-04136611819GO:0051130
GeneOntologyBiologicalProcessregulation of canonical NF-kappaB signal transduction

DHX36 TRAF1 TANK ANGPT1 TRIM34 UFL1 TLR3 FLOT1

3.20e-042981188GO:0043122
GeneOntologyBiologicalProcessTie signaling pathway

ANGPT1 ANGPT2

3.21e-0451182GO:0048014
GeneOntologyBiologicalProcesscentrosome cycle

ROCK2 CNTROB CEP250 CDK5RAP2 CEP295 CROCC

3.65e-041641186GO:0007098
GeneOntologyBiologicalProcessregulation of establishment of cell polarity

ROCK2 KIF20B RNF41

3.83e-04251183GO:2000114
GeneOntologyBiologicalProcessregulation of cilium assembly

SYNE1 DZIP1 CNTROB CCDC88A CROCC

3.92e-041081185GO:1902017
GeneOntologyBiologicalProcesspositive regulation of organelle organization

ROCK2 TPR DHX36 UFL1 DZIP1 MFN1 VPS13D CCDC88A CDK5RAP2 CEP295 CROCC

4.59e-0457411811GO:0010638
GeneOntologyBiologicalProcessplasma membrane bounded cell projection assembly

SYNE1 CEP290 DZIP1 CNTROB CEP164 FSIP2 BLOC1S6 CCDC88A CEP250 CFAP57 CROCC SPAG17

4.62e-0467011812GO:0120031
GeneOntologyBiologicalProcessciliary basal body organization

DZIP1 CROCC

4.80e-0461182GO:0032053
GeneOntologyBiologicalProcesspositive regulation of centrosome duplication

ROCK2 CEP295

4.80e-0461182GO:0010825
GeneOntologyBiologicalProcesspositive regulation of cell projection organization

DHX36 DZIP1 MFN1 IQGAP1 CCDC88A TENM3 MACF1 CROCC GOLGA4 CREB3L2

5.49e-0449411810GO:0031346
GeneOntologyBiologicalProcesscell projection assembly

SYNE1 CEP290 DZIP1 CNTROB CEP164 FSIP2 BLOC1S6 CCDC88A CEP250 CFAP57 CROCC SPAG17

5.62e-0468511812GO:0030031
GeneOntologyBiologicalProcesspost-Golgi vesicle-mediated transport

NBEA GCC2 MACF1 GOLGA4 DOP1B

6.12e-041191185GO:0006892
GeneOntologyBiologicalProcessregulation of establishment or maintenance of cell polarity

ROCK2 KIF20B RNF41

6.62e-04301183GO:0032878
GeneOntologyBiologicalProcessestablishment or maintenance of cell polarity

ROCK2 CEP290 KIF20B CDK5RAP2 MACF1 RNF41 ARHGEF2

7.00e-042571187GO:0007163
GeneOntologyCellularComponentcentriole

CCHCR1 CEP290 DZIP1 CNTROB CEP164 CCDC88A CEP250 CEP295 CROCC

7.19e-071721219GO:0005814
GeneOntologyCellularComponentmicrotubule organizing center

ROCK2 CCHCR1 CEP290 CDH23 E2F1 DZIP1 CNTROB KIF20B CEP164 KIF7 CCDC88A HOOK3 CEP112 CEP250 CDK5RAP2 CEP295 CROCC FLOT1 KIF17

1.37e-0691912119GO:0005815
GeneOntologyCellularComponentcentrosome

ROCK2 CEP290 CDH23 E2F1 DZIP1 CNTROB KIF20B CEP164 CCDC88A HOOK3 CEP112 CEP250 CDK5RAP2 CEP295 CROCC FLOT1

9.55e-0677012116GO:0005813
GeneOntologyCellularComponentmicrotubule

KIF20B IQGAP1 KIF7 ARHGAP4 HOOK3 NAV1 CDK5RAP2 MACF1 CEP295 ARHGEF2 SPAG17 KIF17

6.28e-0553312112GO:0005874
GeneOntologyCellularComponenttrans-Golgi network

NBEA MICALL1 SLC30A5 GCC2 GOLGA1 VPS13B GOLGA4 ECE2 DOP1B

7.39e-053061219GO:0005802
GeneOntologyCellularComponentphotoreceptor inner segment

SPTBN2 CDH23 CEP250 CROCC KIF17

9.01e-05781215GO:0001917
GeneOntologyCellularComponentpolymeric cytoskeletal fiber

KRT78 KRT33A KIF20B IQGAP1 KIF7 ARHGAP4 BLOC1S6 HOOK3 NAV1 CDK5RAP2 MACF1 CEP295 ARHGEF2 SPAG17 KIF17

2.18e-0489912115GO:0099513
GeneOntologyCellularComponentGolgi apparatus subcompartment

NBEA MICALL1 SLC30A5 GCC2 CHPF2 GOLGA1 VPS13B GOLGA4 ECE2 DOP1B

2.57e-0444312110GO:0098791
GeneOntologyCellularComponentsupramolecular fiber

KRT78 KRT33A SYNE1 KIF20B IQGAP1 KIF7 ARHGAP4 BLOC1S6 HOOK3 NAV1 CDK5RAP2 MACF1 CEP295 ARHGEF2 SPAG17 KIF17 NBR1

4.49e-04117912117GO:0099512
GeneOntologyCellularComponentsupramolecular polymer

KRT78 KRT33A SYNE1 KIF20B IQGAP1 KIF7 ARHGAP4 BLOC1S6 HOOK3 NAV1 CDK5RAP2 MACF1 CEP295 ARHGEF2 SPAG17 KIF17 NBR1

4.85e-04118712117GO:0099081
GeneOntologyCellularComponentciliary basal body

CEP290 DZIP1 KIF7 CCDC88A CEP250 KIF17

9.65e-041951216GO:0036064
GeneOntologyCellularComponentribonucleoprotein granule

ROCK2 DDX19B DHX36 SYNE1 FASTKD2 IQGAP1 TAF5L

1.42e-032871217GO:0035770
GeneOntologyCellularComponentciliary transition fiber

DZIP1 CEP164

1.45e-03101212GO:0097539
DomainPrefoldin

TPR TANK ANGPT1 KIF20B WTAP CFAP57 CROCC

3.73e-07721197IPR009053
Domain-

GCC2 GOLGA1 GOLGA4

2.93e-051011931.10.220.60
DomainGrip

GCC2 GOLGA1 GOLGA4

4.01e-05111193SM00755
DomainGRIP

GCC2 GOLGA1 GOLGA4

4.01e-05111193PF01465
DomainGRIP_dom

GCC2 GOLGA1 GOLGA4

5.32e-05121193IPR000237
DomainGRIP

GCC2 GOLGA1 GOLGA4

5.32e-05121193PS50913
DomainCH

SYNE1 SPTBN2 IQGAP1 MICALL1 MACF1

5.87e-05651195SM00033
DomainCH

SYNE1 SPTBN2 IQGAP1 MICALL1 MACF1

8.39e-05701195PF00307
Domain-

SYNE1 SPTBN2 IQGAP1 MICALL1 MACF1

8.98e-057111951.10.418.10
DomainCH

SYNE1 SPTBN2 IQGAP1 MICALL1 MACF1

1.03e-04731195PS50021
DomainCH-domain

SYNE1 SPTBN2 IQGAP1 MICALL1 MACF1

1.17e-04751195IPR001715
DomainSHR-BD

VPS13D VPS13B

2.40e-0441192IPR009543
DomainLRRC37AB_C

LRRC37A2 LRRC37A

2.40e-0441192IPR029423
DomainLRRC37AB_C

LRRC37A2 LRRC37A

2.40e-0441192PF14914
DomainVPS13_C

VPS13D VPS13B

2.40e-0441192PF16909
DomainLRRC37_N

LRRC37A2 LRRC37A

2.40e-0441192IPR032754
DomainVPS13_C

VPS13D VPS13B

2.40e-0441192IPR031645
DomainLRRC37

LRRC37A2 LRRC37A

2.40e-0441192PF15779
DomainSHR-BD

VPS13D VPS13B

2.40e-0441192PF06650
DomainLRRC37A/B-like

LRRC37A2 LRRC37A

2.40e-0441192IPR015753
DomainBZIP_BASIC

ATF7 CREBRF MAFB CREB3L2

3.61e-04531194PS00036
DomainbZIP

ATF7 CREBRF MAFB CREB3L2

3.87e-04541194IPR004827
DomainSpectrin

SYNE1 SPTBN2 MACF1

4.07e-04231193PF00435
DomainACTININ_2

SYNE1 SPTBN2 MACF1

4.07e-04231193PS00020
DomainACTININ_1

SYNE1 SPTBN2 MACF1

4.07e-04231193PS00019
DomainActinin_actin-bd_CS

SYNE1 SPTBN2 MACF1

4.07e-04231193IPR001589
DomainHOOK

CCDC88A HOOK3

5.94e-0461192PF05622
DomainHook-related_fam

CCDC88A HOOK3

5.94e-0461192IPR008636
DomainPH

ROCK2 PLEKHG4 SPTBN2 PLEKHA6 PRKD3 PLEKHO2 ARHGEF2

6.66e-042291197PF00169
DomainZF_DAG_PE_1

ROCK2 PRKD3 ARHGEF2 ARHGAP45

7.41e-04641194PS00479
DomainZF_DAG_PE_2

ROCK2 PRKD3 ARHGEF2 ARHGAP45

7.41e-04641194PS50081
DomainC1

ROCK2 PRKD3 ARHGEF2 ARHGAP45

7.86e-04651194SM00109
DomainSpectrin_repeat

SYNE1 SPTBN2 MACF1

8.17e-04291193IPR002017
DomainPeptidase_M13_C

ECEL1 ECE2

8.28e-0471192IPR018497
DomainPeptidase_M13

ECEL1 ECE2

8.28e-0471192IPR000718
DomainPeptidase_M13_N

ECEL1 ECE2

8.28e-0471192PF05649
DomainPeptidase_M13_N

ECEL1 ECE2

8.28e-0471192IPR008753
DomainPeptidase_M13

ECEL1 ECE2

8.28e-0471192PF01431
DomainPE/DAG-bd

ROCK2 PRKD3 ARHGEF2 ARHGAP45

8.33e-04661194IPR002219
DomainSPEC

SYNE1 SPTBN2 MACF1

1.09e-03321193SM00150
DomainSpectrin/alpha-actinin

SYNE1 SPTBN2 MACF1

1.09e-03321193IPR018159
DomainChorein_N

VPS13D VPS13B

1.10e-0381192PF12624
DomainVPS13_N

VPS13D VPS13B

1.10e-0381192IPR026854
DomainTF_DNA-bd

ATF7 MAFB CREB3L2

1.67e-03371193IPR008917
DomainPH

ROCK2 PLEKHG4 SPTBN2 PLEKHA6 PRKD3 PLEKHO2 ARHGEF2

2.04e-032781197SM00233
DomainPH_DOMAIN

ROCK2 PLEKHG4 SPTBN2 PLEKHA6 PRKD3 PLEKHO2 ARHGEF2

2.08e-032791197PS50003
DomainPH_domain

ROCK2 PLEKHG4 SPTBN2 PLEKHA6 PRKD3 PLEKHO2 ARHGEF2

2.12e-032801197IPR001849
DomainKinesin_motor_CS

KIF20B KIF7 KIF17

2.25e-03411193IPR019821
DomainKinesin-like_fam

KIF20B KIF7 KIF17

2.58e-03431193IPR027640
Domain-

KIF20B KIF7 KIF17

2.76e-034411933.40.850.10
DomainKinesin

KIF20B KIF7 KIF17

2.76e-03441193PF00225
DomainKISc

KIF20B KIF7 KIF17

2.76e-03441193SM00129
DomainKINESIN_MOTOR_1

KIF20B KIF7 KIF17

2.76e-03441193PS00411
DomainKinesin_motor_dom

KIF20B KIF7 KIF17

2.76e-03441193IPR001752
DomainKINESIN_MOTOR_2

KIF20B KIF7 KIF17

2.76e-03441193PS50067
DomainBRLZ

ATF7 MAFB CREB3L2

4.44e-03521193SM00338
DomainBZIP

ATF7 MAFB CREB3L2

4.69e-03531193PS50217
DomainLRR_TYP

LRRC37A2 LRRC37A ELFN1 LRFN5 TLR3

5.53e-031771195SM00369
DomainLeu-rich_rpt_typical-subtyp

LRRC37A2 LRRC37A ELFN1 LRFN5 TLR3

5.53e-031771195IPR003591
DomainC1_1

ROCK2 PRKD3 ARHGEF2

5.75e-03571193PF00130
DomainPH_dom-like

ROCK2 PLEKHG4 SPTBN2 NBEA PLEKHA6 PRKD3 PLEKHO2 ARHGEF2

5.96e-034261198IPR011993
DomainARM-type_fold

TNPO1 DOCK3 USP34 NBEA APOB USP9Y ARFGEF3

6.04e-033391197IPR016024
PathwayREACTOME_ACTIVATION_OF_PUMA_AND_TRANSLOCATION_TO_MITOCHONDRIA

PPP1R13B E2F1 TP53BP2

2.06e-059903M26946
PathwayREACTOME_RHOA_GTPASE_CYCLE

ROCK2 PLEKHG4 IQGAP1 ARHGAP4 ARHGEF2 FLOT1 ARHGAP45

4.59e-05149907M41805
Pubmed

A Conserved Role for Girdin in Basal Body Positioning and Ciliogenesis.

CEP290 CEP164 CCDC88A CEP250 CROCC

2.72e-118122527623382
Pubmed

The human cytoplasmic dynein interactome reveals novel activators of motility.

CCHCR1 TANK ESYT1 SPTBN2 CEP290 PPP1R13B CEP164 IQGAP1 KIF7 MICALL1 CCDC88A HOOK3 CEP250 CEP295 MINDY4 ARHGEF2 FLOT1 TP53BP2

1.19e-098531221828718761
Pubmed

A central chaperone-like role for 14-3-3 proteins in human cells.

DDX19B KRT78 ESYT1 DZIP1 WDR59 MICALL1 ARFGEF3 FSIP2 VPS13D CCDC88A KCNQ5 CEP112 NAV1 MACF1 ARHGEF2 GOLGA4 TP53BP2 DOP1B

1.38e-098611221836931259
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

SYNE1 SLC12A5 ARFGEF3 TENM3 GCC2 NAV1 MACF1 CHPF2 CROCC KIF17 VPS13B DOP1B

2.29e-084071221212693553
Pubmed

ASPP1 and ASPP2 are new transcriptional targets of E2F.

PPP1R13B E2F1 TP53BP2

4.21e-083122315731768
Pubmed

The tumor suppressor proteins ASPP1 and ASPP2 interact with C-Nap1 and regulate centrosome linker reassembly.

PPP1R13B CEP250 TP53BP2

4.21e-083122325660448
Pubmed

Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.

ROCK2 TPR SYNE1 SPTBN2 NBEA IQGAP1 KIF7 SLC12A5 CCDC88A HOOK3 NAV1 CDK5RAP2 MACF1 ARHGEF2 GOLGA1 GOLGA4 TP53BP2

4.85e-089631221728671696
Pubmed

Novel asymmetrically localizing components of human centrosomes identified by complementary proteomics methods.

CEP290 CNTROB CEP164 CEP112 CEP250 CDK5RAP2 CEP295 CROCC

5.11e-08146122821399614
Pubmed

The trans-Golgi network GRIP-domain proteins form alpha-helical homodimers.

GCC2 GOLGA1 GOLGA4

1.68e-074122315654769
Pubmed

A BioID-Derived Proximity Interactome for SARS-CoV-2 Proteins.

SYNE1 PLEKHA6 MICALL1 CCDC88A HOOK3 SLC30A5 TENM3 PLEKHO2 SNX8 NAV1 SNU13 MACF1 NBR1 GOLGA4

2.52e-077191221435337019
Pubmed

The CP110-interacting proteins Talpid3 and Cep290 play overlapping and distinct roles in cilia assembly.

CEP290 CEP164 CEP250 CROCC

5.36e-0719122424421332
Pubmed

Interaction of Arl1-GTP with GRIP domains recruits autoantigens Golgin-97 and Golgin-245/p230 onto the Golgi.

GCC2 GOLGA1 GOLGA4

8.36e-076122312972563
Pubmed

Cep44 functions in centrosome cohesion by stabilizing rootletin.

CEP250 CDK5RAP2 CROCC

8.36e-076122331974111
Pubmed

Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.

TNPO1 EXOSC10 ESYT1 SYNE1 SPTBN2 MRPL28 UFL1 FASTKD2 DZIP1 KIF7 MICALL1 CCDC88A CDK5RAP2 MACF1 FLOT1 NBR1 VPS13B GOLGA4 MAST3

1.08e-0614871221933957083
Pubmed

Disrupted in Schizophrenia 1 Interactome: evidence for the close connectivity of risk genes and a potential synaptic basis for schizophrenia.

SYNE1 PPP1R13B NBEA CCDC88A MACF1 CEP295 GOLGA4

1.12e-06151122717043677
Pubmed

A human MAP kinase interactome.

TPR SYNE1 SPTBN2 CEP290 PPP1R13B PLEKHA6 BLOC1S6 CCDC88A CEP250 NAV1 MACF1

1.23e-064861221120936779
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

ROCK2 DOCK3 ANGPT1 SPTBN2 CEP290 PLEKHA6 WDR59 SMYD4 VPS13D MACF1 MAST3

1.42e-064931221115368895
Pubmed

Prediction of the coding sequences of unidentified human genes. XI. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.

USP34 ESYT1 SYNE1 PPP1R13B UFL1 MACF1

1.59e-0610112269872452
Pubmed

Proximity interactions among centrosome components identify regulators of centriole duplication.

CCHCR1 CNTROB KIF7 CEP250 CDK5RAP2 CEP295

1.59e-06101122624613305
Pubmed

Proteomic characterization of the human centrosome by protein correlation profiling.

CEP290 CEP164 CDK5RAP2 CROCC

2.03e-0626122414654843
Pubmed

Novel link between E2F and p53: proapoptotic cofactors of p53 are transcriptionally upregulated by E2F.

PPP1R13B E2F1 TP53BP2

2.33e-068122315706352
Pubmed

A Multipronged Unbiased Strategy Guides the Development of an Anti-EGFR/EPHA2-Bispecific Antibody for Combination Cancer Therapy.

ROCK2 ESYT1 PPP1R13B UFL1 DZIP1 PLEKHA6 CCDC88A SLC30A5 TENM3 MACF1

2.51e-064211221036976175
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

USP34 DHX36 UFL1 FASTKD2 DZIP1 IQGAP1 MICALL1 ARHGAP4 CCDC88A CDK5RAP2 NBR1

2.79e-065291221114621295
Pubmed

HENA, heterogeneous network-based data set for Alzheimer's disease.

SYNE1 PPP1R13B CCDC88A NAV1 MACF1 GOLGA4

4.34e-06120122631413325
Pubmed

E-cadherin interactome complexity and robustness resolved by quantitative proteomics.

ESYT1 SPTBN2 PPP1R13B PLEKHA6 IQGAP1 MICALL1 TENM3 PLEKHO2 MACF1 FLOT1 TP53BP2

5.22e-065651221125468996
Pubmed

Comparative proximity biotinylation implicates the small GTPase RAB18 in sterol mobilization and biosynthesis.

TNPO1 ROCK2 TPR ESYT1 UFL1 VPS13D SLC30A5 GCC2 CROCC VPS13B GOLGA4

5.48e-065681221137774976
Pubmed

Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method.

TNPO1 DMTF1 TPR CCHCR1 USP34 EXOSC10 SALL4 APOB BRD8 CEP112 CDK5RAP2 MACF1 P2RY14 CEP295 VPS13B

6.34e-0610841221511544199
Pubmed

Protein-protein interactions between large proteins: two-hybrid screening using a functionally classified library composed of long cDNAs.

SPTBN2 VPS13D NAV1 CDK5RAP2 MACF1 MAST3

6.88e-06130122612421765
Pubmed

Probing nuclear pore complex architecture with proximity-dependent biotinylation.

DDX19B TPR ESYT1 SYNE1 CEP250

7.90e-0677122524927568
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

DOCK3 USP34 MAN2A2 ESYT1 MED14 ZNF236 IDUA CNTROB WDR59 MICALL1 PLEKHO2 SNX8 NAV1 MLLT1 ARHGEF2

7.97e-0611051221535748872
Pubmed

Cep120 and TACCs control interkinetic nuclear migration and the neural progenitor pool.

CEP290 CEP164 CDK5RAP2

1.17e-0513122317920017
Pubmed

C5orf51 is a component of the MON1-CCZ1 complex and controls RAB7A localization and stability during mitophagy.

ESYT1 NBEA WDR59 PRKD3 ARFGEF3 VPS13D SLC30A5 VPS13B GOLGA4 DOP1B

1.21e-055041221034432599
Pubmed

Admission angiopoietin levels in children with septic shock.

ANGPT1 ANGPT2

1.22e-052122218092380
Pubmed

Dynamic changes in serum angiopoietin-1, angiopoietin-2, and angiopoietin-2/angiopoietin-1 ratio in acute myocardial infarction patients treated with primary percutaneous coronary intervention.

ANGPT1 ANGPT2

1.22e-052122222642477
Pubmed

Sonic hedgehog inversely regulates the expression of angiopoietin-1 and angiopoietin-2 in fibroblasts.

ANGPT1 ANGPT2

1.22e-052122217273793
Pubmed

Preliminary observations on ANGPT1 and ANGPT2 polymorphisms in systemic sclerosis: ANGPT2 rs2442598 and rs3739390 are associated with disease susceptibility and diffuse disease subtype.

ANGPT1 ANGPT2

1.22e-052122234643357
Pubmed

Interaction between p230 and MACF1 is associated with transport of a glycosyl phosphatidyl inositol-anchored protein from the Golgi to the cell periphery.

MACF1 GOLGA4

1.22e-052122215265687
Pubmed

Endothelial function in patients with metabolic syndrome and erectile dysfunction: a question of angiopoietin imbalance?

ANGPT1 ANGPT2

1.22e-052122223785018
Pubmed

Angiopoietin-2 levels as a biomarker of cardiovascular risk in patients with hypertension.

ANGPT1 ANGPT2

1.22e-052122218382887
Pubmed

Downregulated mRNA expression of ASPP and the hypermethylation of the 5'-untranslated region in cancer cell lines retaining wild-type p53.

PPP1R13B TP53BP2

1.22e-052122215757645
Pubmed

Angiopoietin-1 and -2 exert antagonistic functions in tumor angiogenesis, yet both induce lymphangiogenesis.

ANGPT1 ANGPT2

1.22e-052122221778249
Pubmed

Angiogenic axis angiopoietin-1 and angiopoietin-2/Tie-2 in non-small cell lung cancer: a bronchoalveolar lavage and serum study.

ANGPT1 ANGPT2

1.22e-052122223835996
Pubmed

Angiopoietin-1 protects myocardial endothelial cell function blunted by angiopoietin-2 and high glucose condition.

ANGPT1 ANGPT2

1.22e-052122221113176
Pubmed

Angiopoietin-1 and angiopoietin-2 as serum biomarkers for ectopic pregnancy and missed abortion: a case-control study.

ANGPT1 ANGPT2

1.22e-052122223099117
Pubmed

Angiopoietin-2 causes pericyte dropout in the normal retina: evidence for involvement in diabetic retinopathy.

ANGPT1 ANGPT2

1.22e-052122215047628
Pubmed

The role of angiopoietins in the development of endothelial cells from cord blood CD34+ progenitors.

ANGPT1 ANGPT2

1.22e-052122215213103
Pubmed

Changes in circulating levels and ratios of angiopoietins during pregnancy but not during the menstrual cycle and controlled ovarian stimulation.

ANGPT1 ANGPT2

1.22e-052122219476937
Pubmed

Pro-Angiogenic Actions of CMC-Derived Extracellular Vesicles Rely on Selective Packaging of Angiopoietin 1 and 2, but Not FGF-2 and VEGF.

ANGPT1 ANGPT2

1.22e-052122231102187
Pubmed

Selective functions of angiopoietins and vascular endothelial growth factor on blood vessels: the concept of "vascular domain".

ANGPT1 ANGPT2

1.22e-052122212858538
Pubmed

Overexpression of angiopoietin-1 and angiopoietin-2 in hepatocellular carcinoma.

ANGPT1 ANGPT2

1.22e-052122215094228
Pubmed

Effect of HIV-1 Infection on Angiopoietin 1 and 2 Levels and Measures of Microvascular and Macrovascular Endothelial Dysfunction.

ANGPT1 ANGPT2

1.22e-052122234726064
Pubmed

Systemic Angiopoietin-1/2 Dysregulation in Pediatric Sepsis and Septic Shock.

ANGPT1 ANGPT2

1.22e-052122230745813
Pubmed

Imbalance of angiopoietin-1 and angiopoetin-2 in severe dengue and relationship with thrombocytopenia, endothelial activation, and vascular stability.

ANGPT1 ANGPT2

1.22e-052122222949515
Pubmed

Levels of angiopoietins 1 and 2 in induced sputum supernatant in patients with COPD.

ANGPT1 ANGPT2

1.22e-052122222483377
Pubmed

A high angiopoietin-2/angiopoietin-1 ratio is associated with a high risk of septic shock in patients with febrile neutropenia.

ANGPT1 ANGPT2

1.22e-052122223915833
Pubmed

Differential regulation of angiopoietin 1 and angiopoietin 2 during dengue virus infection of human umbilical vein endothelial cells: implications for endothelial hyperpermeability.

ANGPT1 ANGPT2

1.22e-052122223989887
Pubmed

[Promoter methylation of ASPP1 and ASPP2 genes in non-small cell lung cancers].

PPP1R13B TP53BP2

1.22e-052122222169642
Pubmed

Intrahepatic angiopoietin-2 correlates with chronic hepatitis C progression and is induced in hepatitis C virus replicon systems.

ANGPT1 ANGPT2

1.22e-052122228027429
Pubmed

Arterial stiffness in hypertensives in relation to expression of angiopoietin-1 and 2 genes in peripheral monocytes.

ANGPT1 ANGPT2

1.22e-052122220072144
Pubmed

Regulation of angiopoietin expression by bacterial lipopolysaccharide.

ANGPT1 ANGPT2

1.22e-052122218310225
Pubmed

Increased levels of angiopoietins 1 and 2 in sputum supernatant in severe refractory asthma.

ANGPT1 ANGPT2

1.22e-052122222229541
Pubmed

Angiopoietin-2, Angiopoietin-1 and subclinical cardiovascular disease in Chronic Kidney Disease.

ANGPT1 ANGPT2

1.22e-052122227991547
Pubmed

Epigenetic silence of ankyrin-repeat-containing, SH3-domain-containing, and proline-rich-region- containing protein 1 (ASPP1) and ASPP2 genes promotes tumor growth in hepatitis B virus-positive hepatocellular carcinoma.

PPP1R13B TP53BP2

1.22e-052122220034025
Pubmed

Reduced Ang2 expression in aging endothelial cells.

ANGPT1 ANGPT2

1.22e-052122227137842
Pubmed

Angiopoietins as serum biomarkers for lymphatic anomalies.

ANGPT1 ANGPT2

1.22e-052122227990590
Pubmed

Evaluation of angiopoietin 1 and 2, vascular endothelial growth factor, and tumor necrosis factor alpha levels in asthmatic children.

ANGPT1 ANGPT2

1.22e-052122225584916
Pubmed

Ratio of angiopoietin-2 to angiopoietin-1 predicts mortality in acute lung injury induced by paraquat.

ANGPT1 ANGPT2

1.22e-052122223302768
Pubmed

Endothelial Tie2/Tek ligands angiopoietin-1 (ANGPT1) and angiopoietin-2 (ANGPT2): regional localization of the human genes to 8q22.3-q23 and 8p23.

ANGPT1 ANGPT2

1.22e-05212229545648
Pubmed

Contrasting actions of selective inhibitors of angiopoietin-1 and angiopoietin-2 on the normalization of tumor blood vessels.

ANGPT1 ANGPT2

1.22e-052122219815705
Pubmed

Angiopoietin-1/angiopoietin-2 ratio for prediction of preeclampsia.

ANGPT1 ANGPT2

1.22e-052122219478794
Pubmed

ASPP1/2-PP1 complexes are required for chromosome segregation and kinetochore-microtubule attachments.

PPP1R13B TP53BP2

1.22e-052122226595804
Pubmed

Resveratrol induces apoptosis in breast cancer cells by E2F1-mediated up-regulation of ASPP1.

PPP1R13B E2F1

1.22e-052122221479363
Pubmed

Angiogenic response to major lung resection for non-small cell lung cancer with video-assisted thoracic surgical and open access.

ANGPT1 ANGPT2

1.22e-052122223024612
Pubmed

Increased Angiopoietin-1 and -2 levels in human vitreous are associated with proliferative diabetic retinopathy.

ANGPT1 ANGPT2

1.22e-052122236662891
Pubmed

Vitreous levels of angiopoietin-1 and angiopoietin-2 in eyes with retinopathy of prematurity.

ANGPT1 ANGPT2

1.22e-052122221168819
Pubmed

Angiopoietins and Tie-2 expression in angiogenesis and proliferation of human hepatocellular carcinoma.

ANGPT1 ANGPT2

1.22e-052122212717391
Pubmed

Interleukin-24 inhibits influenza A virus replication in vitro through induction of toll-like receptor 3 dependent apoptosis.

IL24 TLR3

1.22e-052122226367324
Pubmed

Association of Angiopoietin Dysregulation in Placental Malaria with Adverse Birth Outcomes.

ANGPT1 ANGPT2

1.22e-052122232399088
Pubmed

Deregulation of levels of angiopoietin-1 and angiopoietin-2 is associated with severe courses of hantavirus infection.

ANGPT1 ANGPT2

1.22e-052122228734140
Pubmed

A quantitative gene expression study suggests a role for angiopoietins in focal nodular hyperplasia.

ANGPT1 ANGPT2

1.22e-052122212612904
Pubmed

Analysis of angiogenic markers in oral squamous cell carcinoma-gene and protein expression.

ANGPT1 ANGPT2

1.22e-052122226044849
Pubmed

Dysregulation of angiopoietins is associated with placental malaria and low birth weight.

ANGPT1 ANGPT2

1.22e-052122220208992
Pubmed

Angiopoietin-1 is an apoptosis survival factor for endothelial cells.

ANGPT1 ANGPT2

1.22e-052122210218485
Pubmed

Angiopoietin-1 and -2 as markers for disease severity in hemolytic uremic syndrome induced by enterohemorrhagic Escherichia coli.

ANGPT1 ANGPT2

1.22e-052122226945868
Pubmed

Gingipains from the Periodontal Pathogen Porphyromonas gingivalis Play a Significant Role in Regulation of Angiopoietin 1 and Angiopoietin 2 in Human Aortic Smooth Muscle Cells.

ANGPT1 ANGPT2

1.22e-052122226283334
Pubmed

Angiopoietin 1 and angiopoietin 2 are associated with medial thickening of hepatic arterial branches in biliary atresia.

ANGPT1 ANGPT2

1.22e-052122224126820
Pubmed

Angiopoietin-1 and angiopoietin-2 in diabetes mellitus: relationship to VEGF, glycaemic control, endothelial damage/dysfunction and atherosclerosis.

ANGPT1 ANGPT2

1.22e-052122215823283
Pubmed

Angiopoietin-1 and -2 mRNA and protein expression in mouse preimplantation embryos and uteri suggests a role in angiogenesis during implantation.

ANGPT1 ANGPT2

1.22e-052122216836957
Pubmed

The ratio of plasma angiopoietin-2 to angiopoietin-1 as a prognostic biomarker in patients with sepsis.

ANGPT1 ANGPT2

1.22e-052122232059166
Pubmed

Angiopoietin 1 and angiopoietin 2 in follicular fluid of women undergoing a long protocol.

ANGPT1 ANGPT2

1.22e-052122222000910
Pubmed

Rootletin interacts with C-Nap1 and may function as a physical linker between the pair of centrioles/basal bodies in cells.

CEP250 CROCC

1.22e-052122216339073
Pubmed

Serum angiopoietin-1 and -2 levels discriminate cerebral malaria from uncomplicated malaria and predict clinical outcome in African children.

ANGPT1 ANGPT2

1.22e-052122219300530
Pubmed

Angiopoietin-2/angiopoietin-1 as non-invasive biomarker of cirrhosis in chronic hepatitis C.

ANGPT1 ANGPT2

1.22e-052122227956798
Pubmed

Endometrial angiopoietin expression and modulation by thrombin and steroid hormones: a mechanism for abnormal angiogenesis following long-term progestin-only contraception.

ANGPT1 ANGPT2

1.22e-052122215161644
Pubmed

C-NAP1 and rootletin restrain DNA damage-induced centriole splitting and facilitate ciliogenesis.

CEP250 CROCC

1.22e-052122223070519
Pubmed

A prospective study of endothelial activation biomarkers, including plasma angiopoietin-1 and angiopoietin-2, in Kenyan women initiating antiretroviral therapy.

ANGPT1 ANGPT2

1.22e-052122223734875
Pubmed

Apoptosis stimulating protein of p53 (ASPP) 1 and ASPP2 m-RNA expression in oral cancer.

PPP1R13B TP53BP2

1.22e-052122232987288
Pubmed

The angiopoietin 1/angiopoietin 2 balance as a prognostic marker in primary glioblastoma multiforme.

ANGPT1 ANGPT2

1.22e-052122218991494
Pubmed

Angiopoietin-2 is required for postnatal angiogenesis and lymphatic patterning, and only the latter role is rescued by Angiopoietin-1.

ANGPT1 ANGPT2

1.22e-052122212361603
Pubmed

Angiopoietins bind thrombomodulin and inhibit its function as a thrombin cofactor.

ANGPT1 ANGPT2

1.22e-052122229323190
InteractionCEP135 interactions

CCHCR1 TANK CEP290 PPP1R13B CNTROB KIF20B CEP164 KIF7 CCDC88A CEP112 CEP250 NAV1 CDK5RAP2 CEP295 NBR1 TP53BP2

6.90e-1227212016int:CEP135
InteractionNDC80 interactions

ROCK2 CCHCR1 KRT78 CEP290 PPP1R13B CNTROB CEP164 KIF7 BLOC1S6 GCC2 CEP250 NAV1 CDK5RAP2 CEP295 TP53BP2

5.51e-1031212015int:NDC80
InteractionWHAMMP3 interactions

CCHCR1 ATF7 SYNE1 HOOK3 GCC2 CEP250 CDK5RAP2 CROCC GOLGA1 TP53BP2

2.36e-0911912010int:WHAMMP3
InteractionPCM1 interactions

CCHCR1 CEP290 PPP1R13B CNTROB CEP164 KIF7 HOOK3 CEP112 GCC2 CEP250 NAV1 CDK5RAP2 CEP295 MINDY4 GOLGA1 TP53BP2

6.51e-0943412016int:PCM1
InteractionAPC interactions

IL24 TPR TRAF1 SYNE1 SPTBN2 PPP1R13B IQGAP1 KIF7 BLOC1S6 HOOK3 CEP250 NAV1 MACF1 FLOT1 GOLGA1

1.10e-0838912015int:APC
InteractionKRT19 interactions

CCHCR1 KRT78 CEP290 PPP1R13B CNTROB CEP164 KIF7 FANCG HOOK3 GCC2 CDK5RAP2 CEP295 TP53BP2

1.38e-0828212013int:KRT19
InteractionNIN interactions

CCHCR1 CEP290 PPP1R13B CEP164 IQGAP1 KIF7 ARFGEF3 CEP250 SNU13 CEP295 ARHGEF2 FLOT1 TP53BP2

2.31e-0735912013int:NIN
InteractionRALBP1 interactions

CCHCR1 PPP1R13B CEP164 KIF7 HOOK3 CEP250 CDK5RAP2 CROCC GOLGA4 TP53BP2

3.04e-0719812010int:RALBP1
InteractionSYNE3 interactions

CCHCR1 ESYT1 PPP1R13B UFL1 CNTROB CEP164 KIF7 KCNQ5 NAV1 CDK5RAP2 MACF1 CEP295 NBR1 TP53BP2

4.13e-0744412014int:SYNE3
InteractionGOLGA1 interactions

PPP1R13B ARFGEF3 GCC2 NAV1 MACF1 NBR1 GOLGA1 GOLGA4 TP53BP2

1.52e-061831209int:GOLGA1
InteractionMAPRE1 interactions

DHX36 CEP290 PPP1R13B CCDC88A HOOK3 GCC2 CEP250 NAV1 SNU13 CDK5RAP2 MACF1 ARHGEF2 NBR1 GOLGA1

2.33e-0651412014int:MAPRE1
InteractionCGN interactions

PPP1R13B IQGAP1 MICALL1 HOOK3 NAV1 ARHGEF2 MAST3 TP53BP2

3.58e-061521208int:CGN
InteractionTBK1 interactions

TPR SIKE1 TRAF1 TANK UFL1 APOB CNTROB BLOC1S6 TLR3 CDK5RAP2 RNF41 NBR1

5.11e-0640212012int:TBK1
InteractionDTNBP1 interactions

CCHCR1 SYNE1 CEP290 NBEA BLOC1S6 NAV1 CDK5RAP2 MACF1

5.75e-061621208int:DTNBP1
InteractionSSX2IP interactions

CCHCR1 CEP290 PPP1R13B KIF7 FANCG HOOK3 CEP250 CDK5RAP2 GOLGA1 TP53BP2

8.84e-0628812010int:SSX2IP
InteractionYWHAZ interactions

KRT78 ESYT1 SPTBN2 UFL1 DZIP1 WTAP MICALL1 FSIP2 VPS13D CCDC88A KCNQ5 PLEKHO2 CEP112 GCC2 NAV1 CDK5RAP2 MACF1 RNF41 ARHGEF2 CWF19L1 MAST3 TP53BP2

9.67e-06131912022int:YWHAZ
InteractionPPP1R13B interactions

CCHCR1 TRAF1 PPP1R13B E2F1 CEP250 FLOT1 ARHGAP45 GOLGA1

1.06e-051761208int:PPP1R13B
InteractionLZTS2 interactions

TPR CEP290 PPP1R13B CNTROB CEP164 IQGAP1 KIF7 CCDC88A CEP112 CEP250 RNF41 CEP295 FLOT1

1.16e-0551212013int:LZTS2
InteractionTRIM52 interactions

CEP290 CEP164 CCDC88A HOOK3 CDK5RAP2 CEP295 ARHGEF2

1.49e-051331207int:TRIM52
InteractionYWHAE interactions

ESYT1 UFL1 FASTKD2 WTAP IQGAP1 MICALL1 CCDC88A KCNQ5 PLEKHO2 CEP112 GCC2 CEP250 NAV1 MACF1 MINDY4 ARHGEF2 ARHGAP45 NBR1 CWF19L1 MAST3 TP53BP2

1.53e-05125612021int:YWHAE
InteractionLURAP1 interactions

ROCK2 CCHCR1 PLEKHG4 KIF7 BLOC1S6 CDK5RAP2 TP53BP2

1.81e-051371207int:LURAP1
InteractionSEPTIN10 interactions

CNTROB KIF20B KIF7 CCDC88A HOOK3 GCC2 CDK5RAP2

2.49e-051441207int:SEPTIN10
InteractionYWHAH interactions

KRT78 ESYT1 CEP290 DZIP1 IQGAP1 KIF7 MICALL1 ARFGEF3 VPS13D CCDC88A KCNQ5 CEP112 NAV1 MACF1 ARHGEF2 GOLGA4 MAST3 TP53BP2 DOP1B

2.71e-05110212019int:YWHAH
InteractionCEP89 interactions

CEP164 KIF7 NAV1 MLLT1 CEP295 FLOT1 TP53BP2

2.85e-051471207int:CEP89
InteractionIRF3 interactions

TANK UFL1 CCDC88A MAFB RNF41 FLOT1 NBR1

3.11e-051491207int:IRF3
InteractionPXN interactions

CNTROB IQGAP1 KIF7 MICALL1 GCC2 CDK5RAP2 MACF1 ARHGEF2 GOLGA4 CREB3L2

3.17e-0533412010int:PXN
InteractionCCDC8 interactions

TNPO1 TPR KRT78 SPTBN2 CEP290 UFL1 APOB IQGAP1 KIF7 HOOK3 CEP250 MACF1 ARHGEF2 FLOT1

3.64e-0565612014int:CCDC8
InteractionNUP62 interactions

DDX19B TPR CCHCR1 TANK PPP1R13B KIF7 BLOC1S6 CCDC88A CEP250

3.80e-052731209int:NUP62
InteractionOFD1 interactions

TANK CEP290 CNTROB CEP164 IQGAP1 CDK5RAP2 CEP295 FLOT1 GOLGA1 TP53BP2

4.37e-0534712010int:OFD1
InteractionGJA1 interactions

ROCK2 ESYT1 NBEA UFL1 APOB DZIP1 CCDC88A SLC30A5 GCC2 MACF1 NBR1 VPS13B GOLGA4

4.49e-0558312013int:GJA1
InteractionSASS6 interactions

TANK CEP290 CNTROB CEP164 KIF7 CEP250 CDK5RAP2

4.70e-051591207int:SASS6
InteractionSTX4 interactions

ESYT1 SYNE1 PPP1R13B UFL1 CCDC88A KCNQ5 VAMP1 NAV1 NBR1 GOLGA4 TP53BP2

5.08e-0542812011int:STX4
InteractionDISC1 interactions

CCHCR1 DHX36 SYNE1 CEP290 CEP164 KIF7 CCDC88A KCNQ5 NAV1 MACF1 FLOT1

5.19e-0542912011int:DISC1
InteractionCCDC18 interactions

CEP290 KIF7 CEP250 CDK5RAP2 GOLGA1

5.32e-05681205int:CCDC18
InteractionMLF1 interactions

TANK APOB KIF20B CCDC88A CDK5RAP2 CEP295

5.91e-051131206int:MLF1
InteractionRPS6 interactions

ROCK2 DHX36 EXOSC10 PPP1R13B MRPL28 UFL1 APOB USP9Y ZC3H3 IQGAP1 GVINP1 CEP250 SNU13 MINDY4 ARHGEF2 TP53BP2

6.20e-0587412016int:RPS6
InteractionKRT13 interactions

CCHCR1 KRT78 FANCG BLOC1S6 HOOK3 MINDY4

6.84e-051161206int:KRT13
InteractionBORCS6 interactions

CCHCR1 CNTROB CEP164 WTAP CEP250 NAV1 CDK5RAP2

7.18e-051701207int:BORCS6
InteractionPEX14 interactions

CNTROB KIF20B IQGAP1 VPS13D GCC2 NAV1 ARHGEF2 CROCC

8.81e-052371208int:PEX14
InteractionDUSP16 interactions

ROCK2 CEP164 CCDC88A HOOK3 NAV1 CDK5RAP2 CEP295 NBR1

8.81e-052371208int:DUSP16
InteractionTNIK interactions

TPR SIKE1 SYNE1 SPTBN2 PPP1R13B NBEA KIF7 MACF1 ARHGEF2 GOLGA4

9.51e-0538112010int:TNIK
InteractionCEP63 interactions

CCHCR1 TANK SYNE1 PPP1R13B KIF7 HOOK3 MACF1

9.92e-051791207int:CEP63
InteractionLAMTOR1 interactions

ROCK2 SPTBN2 NBEA WDR59 IQGAP1 MICALL1 PRKD3 ARFGEF3 BLOC1S6 CCDC88A GCC2 FLOT1 VPS13B GOLGA4

1.01e-0472212014int:LAMTOR1
InteractionYWHAB interactions

ESYT1 DZIP1 IQGAP1 MICALL1 VPS13D CCDC88A HOOK3 KCNQ5 PLEKHO2 CEP112 GCC2 NAV1 MACF1 ARHGEF2 CWF19L1 MAST3 TP53BP2

1.06e-04101412017int:YWHAB
InteractionSYCE1 interactions

CCHCR1 TRAF1 HOOK3 CROCC GOLGA1 GOLGA4

1.13e-041271206int:SYCE1
InteractionTPM3 interactions

CCHCR1 DHX36 UFL1 WTAP IQGAP1 BLOC1S6 HOOK3 ARHGEF2 CROCC GOLGA4

1.15e-0439012010int:TPM3
InteractionYWHAG interactions

DDX19B ESYT1 DZIP1 IQGAP1 KIF7 MICALL1 VPS13D CCDC88A KCNQ5 CEP112 GCC2 CEP250 NAV1 MACF1 MAFB ARHGEF2 NBR1 MAST3 TP53BP2

1.43e-04124812019int:YWHAG
InteractionCEP43 interactions

CCHCR1 CEP290 ARFGEF3 NAV1 CDK5RAP2 CEP295 GOLGA1

1.44e-041901207int:CEP43
InteractionRAB2A interactions

ROCK2 SPTBN2 CEP290 NBEA CNTROB IQGAP1 ARFGEF3 CCDC88A SLC30A5 GCC2 FLOT1 GOLGA4

1.46e-0456712012int:RAB2A
InteractionSQSTM1 interactions

TNPO1 TRAF1 CEP290 PPP1R13B FASTKD2 CEP164 IQGAP1 KIF7 ARFGEF3 CEP112 CEP250 TLR3 NAV1 CDK5RAP2 CROCC FLOT1 NBR1 GOLGA1 TP53BP2

1.57e-04125712019int:SQSTM1
InteractionCDC5L interactions

TNPO1 ROCK2 DDX19B TPR EXOSC10 SYNE1 PPP1R13B UFL1 IQGAP1 BRD8 MACF1 MAFB ARHGEF2 CWF19L1 TP53BP2

1.71e-0485512015int:CDC5L
InteractionDCTN1 interactions

TPR SPTBN2 CEP290 MED14 UFL1 KIF7 CCDC88A HOOK3 NAV1 MACF1 ARHGEF2

1.90e-0449712011int:DCTN1
InteractionPIBF1 interactions

CCHCR1 CEP290 KIF7 CDK5RAP2 ARHGAP45 GOLGA1 TP53BP2

1.97e-042001207int:PIBF1
InteractionPHF21A interactions

TPR CCHCR1 USP34 TRAF1 KIF20B CCDC88A GCC2 NAV1 TP53BP2

2.15e-043431209int:PHF21A
InteractionEXOC1 interactions

CCHCR1 SIKE1 CCDC88A MACF1 CEP295 GOLGA4

2.16e-041431206int:EXOC1
InteractionRAB9A interactions

TANK ESYT1 NBEA UFL1 WDR59 MICALL1 ARFGEF3 VPS13D GCC2 VPS13B GOLGA4 DOP1B

2.28e-0459512012int:RAB9A
InteractionFPR1 interactions

PLEKHG4 UFL1 ARFGEF3 FANCG NAV1 DOP1B

2.51e-041471206int:FPR1
InteractionRHOA interactions

ROCK2 PLEKHG4 ESYT1 SPTBN2 UFL1 FASTKD2 IQGAP1 MICALL1 VPS13D CCDC88A SLC30A5 TENM3 MACF1 ARHGEF2 FLOT1 NBR1 VPS13B GOLGA4

2.58e-04119912018int:RHOA
InteractionLAMP2 interactions

ROCK2 DDX19B ESYT1 SPTBN2 NBEA WDR59 ARFGEF3 SLC30A5 KCNQ5 GCC2 GOLGA4 DOP1B

2.81e-0460912012int:LAMP2
InteractionCD40 interactions

TNPO1 TRAF1 TANK PPP1R13B ARFGEF3 HOOK3

3.11e-041531206int:CD40
InteractionE2F2 interactions

PPP1R13B E2F1 NBR1 TP53BP2

3.23e-04551204int:E2F2
InteractionRAC3 interactions

ROCK2 PLEKHG4 ESYT1 SPTBN2 IQGAP1 MICALL1 CCDC88A SLC30A5 TENM3 MACF1 FLOT1 GOLGA4

3.26e-0461912012int:RAC3
InteractionFHIP2A interactions

NBEA HOOK3 SLC30A5 GOLGA4

3.46e-04561204int:FHIP2A
InteractionP2RY14 interactions

APOB P2RY14

3.48e-0451202int:P2RY14
InteractionZFPL1 interactions

SPTBN2 PPP1R13B NBEA MICALL1 VPS13D CCDC88A SLC30A5 GCC2 VPS13B GOLGA4

3.51e-0444812010int:ZFPL1
InteractionSCGB2A2 interactions

MAN2A2 TEX15 IDUA TENM3 CHPF2 ECEL1 TAF5L

3.82e-042231207int:SCGB2A2
InteractionGJD3 interactions

ESYT1 SYNE1 SPTBN2 UFL1 CCDC88A SLC30A5 GCC2 NBR1 VPS13B GOLGA4

3.89e-0445412010int:GJD3
InteractionCEP128 interactions

TANK CEP290 PPP1R13B CNTROB CEP164 KIF7 NAV1 TP53BP2

4.09e-042971208int:CEP128
InteractionIKBKE interactions

ROCK2 SIKE1 TANK VAMP1 MAFB

4.32e-041061205int:IKBKE
InteractionTICAM1 interactions

TRAF1 TANK TLR3 RNF41

4.51e-04601204int:TICAM1
InteractionMAPRE3 interactions

ROCK2 KIF7 CCDC88A NAV1 CDK5RAP2 MACF1 ARHGEF2

4.59e-042301207int:MAPRE3
InteractionGSK3A interactions

TANK LRRC37A2 CNTROB PRKD3 ARFGEF3 VPS13D CCDC88A MACF1 NBR1 TP53BP2

4.62e-0446412010int:GSK3A
InteractionCEP57 interactions

CCHCR1 CEP290 PPP1R13B IQGAP1 MMRN1 CDK5RAP2

4.65e-041651206int:CEP57
InteractionPLEKHA5 interactions

PPP1R13B PLEKHA6 BLOC1S6 CEP250 ARHGEF2 FLOT1 MAST3

4.71e-042311207int:PLEKHA5
InteractionSYNGAP1 interactions

DOCK3 SPTBN2 NBEA IQGAP1 CCDC88A ELFN1 CEP250 ARHGEF2

5.09e-043071208int:SYNGAP1
InteractionZNF252P-AS1 interactions

PLEKHG4 ARHGAP4 VPS13B

5.43e-04271203int:ZNF252P-AS1
InteractionAMOT interactions

TANK PPP1R13B CNTROB KIF7 CEP250 NAV1 NBR1 TP53BP2

5.66e-043121208int:AMOT
InteractionNUP155 interactions

TNPO1 DDX19B ESYT1 UFL1 KIF7 VPS13D SLC30A5 GCC2 VPS13B GOLGA4

5.72e-0447712010int:NUP155
InteractionCTAG1B interactions

DDX19B CCHCR1 USP34 SIKE1 WDR59

5.79e-041131205int:CTAG1B
InteractionKRT38 interactions

CCHCR1 KRT78 CEP164 KIF7 NAV1 CDK5RAP2

5.80e-041721206int:KRT38
GeneFamilyPleckstrin homology domain containing|Rho guanine nucleotide exchange factors|C2 domain containing

ROCK2 PLEKHG4 SPTBN2 PLEKHA6 PRKD3 PLEKHO2 ARHGEF2

3.26e-05206797682
GeneFamilyKinesins|Pleckstrin homology domain containing

KIF20B KIF7 KIF17

1.06e-0346793622
GeneFamilyBasic leucine zipper proteins

ATF7 MAFB CREB3L2

1.28e-0349793506
CoexpressionHALLMARK_MITOTIC_SPINDLE

CNTROB KIF20B ARHGAP4 CCDC88A HOOK3 CEP250 CDK5RAP2 ARHGEF2

4.41e-061991228M5893
CoexpressionGSE6674_CPG_VS_PL2_3_STIM_BCELL_DN

IL24 TNPO1 DMTF1 TPR UFL1 KCNQ5 P2RY14 CEP295

4.57e-062001228M6938
CoexpressionGSE7509_FCGRIIB_VS_TNFA_IL1B_IL6_PGE_STIM_DC_DN

CCHCR1 BRD8 HOOK3 CEP250 CROCC CCDC157 GOLGA1

8.02e-061541227M6824
CoexpressionBUSSLINGER_GASTRIC_IMMUNE_CELLS

DMTF1 TPR USP34 TRAF1 TANK MAN2A2 ESYT1 SYNE1 IQGAP1 PRKD3 CREBRF ARHGAP4 CCDC88A GVINP1 PLEKHO2 VAMP1 MACF1 ARHGAP45 VPS13B MAST3

1.81e-05149212220M40023
CoexpressionGSE17721_12H_VS_24H_GARDIQUIMOD_BMDC_UP

ESYT1 IQGAP1 UBA7 PLEKHO2 TLR3 P2RY14 ECE2

4.19e-051991227M4148
CoexpressionGSE2405_0H_VS_1.5H_A_PHAGOCYTOPHILUM_STIM_NEUTROPHIL_DN

EXOSC10 E2F1 DZIP1 PRKD3 TAF5L CWF19L1 MAST3

4.19e-051991227M6211
CoexpressionGSE28726_ACT_CD4_TCELL_VS_ACT_VA24NEG_NKTCELL_DN

USP34 SYNE1 WTAP ARHGAP4 UBA7 ARHGAP45 VPS13B

4.33e-052001227M8306
CoexpressionBLANCO_MELO_BRONCHIAL_EPITHELIAL_CELLS_INFLUENZA_A_INFECTION_UP

ROCK2 TRAF1 FSD1L MACF1 MAFB KIF17

4.49e-051371226M34024
CoexpressionBOYLAN_MULTIPLE_MYELOMA_C_D_UP

DDX19B IQGAP1 KIF7 BRD8 HOOK3 CROCC

5.71e-051431226MM788
CoexpressionBOYLAN_MULTIPLE_MYELOMA_C_D_UP

DDX19B IQGAP1 KIF7 BRD8 HOOK3 CROCC

5.71e-051431226M16927
CoexpressionHAMAI_APOPTOSIS_VIA_TRAIL_UP

TNPO1 DHX36 CEP290 UFL1 DZIP1 KIF20B CCDC88A SLC30A5 CEP112 GCC2 CDK5RAP2 GOLGA4

5.78e-0565612212M18979
CoexpressionHOEBEKE_LYMPHOID_STEM_CELL_UP

TPR USP34 MACF1 P2RY14 ARHGAP45

9.21e-05971225M14698
CoexpressionGSE34156_UNTREATED_VS_6H_NOD2_AND_TLR1_TLR2_LIGAND_TREATED_MONOCYTE_DN

DHX36 TRIM34 GVINP1 TLR3 P2RY14 ARHGEF2

1.06e-041601226M8664
CoexpressionAtlasFacebaseRNAseq_e10.5_Maxillary Arch_top-relative-expression-ranked_1000_k-means-cluster#3

ROCK2 TPR MAN2A2 ANGPT1 SYNE1 CEP290 KIF20B GCC2 CDK5RAP2 MACF1 MAFB CEP295 ARHGEF2

1.15e-0643212113Facebase_RNAseq_e10.5_Maxillary Arch_1000_K3
CoexpressionAtlasFacebaseRNAseq_e10.5_Maxillary Arch_top-relative-expression-ranked_1000

ROCK2 TPR MAN2A2 ENOX1 ANGPT1 SYNE1 CEP290 SALL4 KIF20B WTAP KIF7 GCC2 NAV1 CDK5RAP2 MACF1 MAFB CEP295 ARHGEF2 KIF17

3.20e-0698912119Facebase_RNAseq_e10.5_Maxillary Arch_1000
CoexpressionAtlasFacebaseRNAseq_e10.5_Neural Epithelium Overlying Central Eminence_top-relative-expression-ranked_1000_k-means-cluster#1

ROCK2 TPR PLEKHG4 KIF20B GCC2 MACF1 MAFB

4.70e-051661217Facebase_RNAseq_e10.5_Neural Epithelium Overlying Central Eminence_1000_K1
CoexpressionAtlasFacebaseRNAseq_e10.5_Neural Epithelium Flanking Eminence_top-relative-expression-ranked_1000_k-means-cluster#2

ROCK2 DHX36 CEP290 MED14 KIF20B CCDC88A GCC2 CEP295 GOLGA4

7.43e-053111219Facebase_RNAseq_e10.5_Neural Epithelium Flanking Eminence_1000_K2
CoexpressionAtlasFacebaseRNAseq_e10.5_Mandibular Arch_top-relative-expression-ranked_500_k-means-cluster#5

TPR CEP290 KIF20B CCDC88A GCC2 NAV1 MACF1

9.63e-051861217Facebase_RNAseq_e10.5_Mandibular Arch_500_K5
CoexpressionAtlasFacebaseRNAseq_e10.5_Maxillary Arch_top-relative-expression-ranked_500_k-means-cluster#3

ROCK2 MAN2A2 ANGPT1 SYNE1 CEP290 KIF20B GCC2 MAFB

1.08e-042551218Facebase_RNAseq_e10.5_Maxillary Arch_500_K3
CoexpressionAtlasFacebaseRNAseq_e10.5_Maxillary Arch_top-relative-expression-ranked_500

ROCK2 MAN2A2 ENOX1 ANGPT1 SYNE1 CEP290 SALL4 KIF20B GCC2 MAFB KIF17

1.19e-0449212111Facebase_RNAseq_e10.5_Maxillary Arch_500
ToppCellTCGA-Pancreas-Primary_Tumor-Pancreatic_Adenocarcinoma-Ductal_Adenocarcinoma-1|TCGA-Pancreas / Sample_Type by Project: Shred V9

ROCK2 TPR USP34 MED14 VPS13D GCC2 CEP295 VPS13B

4.73e-08186122803db813598b67b1e08f759758a1c2023396921fa
ToppCelldroplet-Marrow-nan-3m|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ROCK2 TPR IQGAP1 CCDC88A GCC2 MACF1 GOLGA4

7.69e-0718412271154a5ad7b8512272b7476f949ddac350910bfb7
ToppCellsevere-low-quality_cells|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

USP34 DHX36 SYNE1 ELFN1 GCC2 MACF1 GOLGA4

1.21e-06197122757ebd552f10d6278623b52a3d484d4b91ae1d028
ToppCellmild-low-quality_cells|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

DMTF1 USP34 SYNE1 USP9Y MACF1 VPS13B GOLGA4

1.30e-061991227f0b0097df0026496470a80d8cc9375ffd8389b00
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Sst-Sst_Myh8_Etv1_|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

ELFN1 SNX8 MAFB ECEL1 ECE2 CREB3L2

3.38e-0614812264d43efee96a6493abd78e9ca41aab73db0c80626
ToppCellfacs-Brain_Non-Myeloid-Striatum-24m-Neuronal-SPN_Neuron_STR|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DDX19B SLC12A5 KCNQ5 TENM3 LRFN5 KIF17

7.00e-061681226b87fc63f9e35dfcfc46cb129ea569e73c5e018bb
ToppCellfacs-Brain_Non-Myeloid-Striatum-24m-Neuronal-medium_spiny_neuron|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DDX19B SLC12A5 KCNQ5 TENM3 LRFN5 KIF17

7.00e-061681226b96a48552f4236a95bbcdce2f1b05041086d7101
ToppCellfrontal_cortex-Neuronal-GABAergic_neuron-Sst-Sst_Myh8_Etv1_|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

ELFN1 SNX8 MAFB ECEL1 CREB3L2

7.13e-06971225f3c3fb260954f594a9ab8e1ac9a01115767cbc7a
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Sst|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

ELFN1 SNX8 MAFB ECEL1 ECE2 CREB3L2

7.49e-0617012268ab67e2b6e30fdf9e9a2c02e31d4df34e751a3ed
ToppCellfacs-Lung-EPCAM-18m-Lymphocytic-Alox5+_Lymphocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TRAF1 ARHGAP4 KCNQ5 CDK5RAP2 P2RY14 CWF19L1

1.04e-051801226b28363626f4d2a552abde3434cc1df2e2121aba5
ToppCellfacs-Lung-EPCAM-18m-Lymphocytic-lymphocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TRAF1 ARHGAP4 KCNQ5 CDK5RAP2 P2RY14 CWF19L1

1.04e-05180122667b062f2ef7e20f392e00c646f4985c415d40de9
ToppCellHealthy-multiplets|World / disease group, cell group and cell class

ENOX1 PLEKHA6 TLR3 SNX8 NAV1 P2RY14

1.07e-051811226f8dbac3cd500cc8d80853312b00d124c27b8fd85
ToppCelldroplet-Marrow-nan-3m-Myeloid-nan|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ROCK2 TPR IQGAP1 CCDC88A GCC2 MACF1

1.11e-051821226f8c73baaaca145e2efc48f10f636feb79c8fc779
ToppCelldroplet-Marrow-nan-3m-Myeloid|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ROCK2 TPR IQGAP1 CCDC88A GCC2 MACF1

1.21e-0518512267adfa929930cfa795cbfbd9f1a0b439e08aa765d
ToppCellLPS_anti-TNF-Mesenchymal_fibroblastic-Fibroblasts-Activated_MatrixFB|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

ANGPT1 SYNE1 PLEKHA6 TENM3 LRFN5 MACF1

1.73e-051971226fdb92985f7df0c280b87d3e43c2394e70786a2c7
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ROCK2 SYNE1 NBEA SLC12A5 KCNQ5 LRFN5

1.78e-0519812268ab40fae14fe02e39bc8c8da187a5cd60c787643
ToppCell(11)_FOXN4+-(2)_GFP_FOXI1|(11)_FOXN4+ / shred by cell type by condition

CEP290 KIF20B VPS13D CCDC88A GCC2 GOLGA4

1.78e-05198122676d40b8c2f8399725b3a62ee2ae0896559cf91eb
ToppCell(03)_KRT6B+-(2)_GFP_FOXI1|(03)_KRT6B+ / shred by cell type by condition

ROCK2 TPR CEP290 BRD8 GCC2 GOLGA4

1.83e-051991226c425e7975f492ed5cfcca022248adb627e1d27d4
ToppCellControl-Fibroblasts-Mesothelial_FB|Control / group, cell type (main and fine annotations)

ENOX1 DZIP1 TENM3 LRFN5 WDR87

4.06e-051391225e769beb031b262dd92c9605b07dbf3c29fb82520
ToppCellPBMC-Severe-Myeloid-cDC-cDC-cDC_11|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

ENOX1 PLEKHA6 TEX15 NAV1 MINDY4

6.61e-0515412255967a0a33456d5930fc492a700ebb015ac050abb
ToppCellPBMC-Severe-Myeloid-cDC-cDC-cDC_11|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

ENOX1 PLEKHA6 TEX15 NAV1 MINDY4

6.82e-051551225fab281db4c275d51240b122be78713c839ba5a95
ToppCellCOVID-19_Moderate-multiplets|World / disease group, cell group and cell class

ENOX1 SYNE1 TLR3 MACF1 GOLGA4

7.03e-051561225afdc025fa75e7926b1cc182c4a33654a2186abb1
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Sst-Sst_Calb2_Pdlim5|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

ELFN1 SNX8 MAFB ECEL1 CREB3L2

7.92e-051601225dd16ca90feb3ae88b6409d6c278b4765da565514
ToppCellfrontal_cortex-Neuronal-GABAergic_neuron-Sst|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

ELFN1 SNX8 MAFB ECE2 CREB3L2

8.16e-051611225dccb61d5e17a8f1c6d1fc146ee389f567659a0f0
ToppCell10x5'-blood-Lymphocytic_T_CD4-T_CD4/CD8|blood / Manually curated celltypes from each tissue

USP34 TRAF1 USP9Y LRRC37A MACF1

8.40e-051621225b4535bcb3f469bc139e73f1122f4070013e5a1de
ToppCellfacs-Lung-3m-Hematologic-myeloid-classical_monocyte-classical_monocyte_l15|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

IL24 CDH23 E2F1 ECE2 MAST3

8.64e-051631225f558ad9569e5137e62a601ba4f073e69ed8f8650
ToppCellfacs-Aorta-Heart-3m-Mesenchymal-fibrocyte|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TRAF1 NUDT17 ARHGAP4 ARHGAP45 MAST3

9.16e-0516512258a52f2dbcbd2bc1662b5e3fac381463fdcc3bf14
ToppCellwk_15-18-Epithelial-Airway_epithelial_progenitor-epi-prox-progenitor_intermediate_|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

DMTF1 SPTBN2 PPP1R13B CHRNA1 ARFGEF3

9.16e-051651225f6887c64af0f26e33316bc5587487e24d76ece2a
ToppCellDendritic_Cells-Donor_02|World / lung cells shred on cell class, cell subclass, sample id

SLC12A5 BRD8 P2RY14 MAFB ARHGAP45

9.42e-051661225fbeb74b98b58085de323f744b18d4a8f7b22d5d4
ToppCellfacs-Marrow-T-cells-3m-Myeloid-promonocyte|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ESYT1 USP9Y CCDC88A TLR3 NAV1

1.05e-041701225a78d9789c3e7c84a36e1bd380192d7aba4a4d443
ToppCellfacs-Marrow-T-cells-3m-Myeloid-monocyte_+_promonocyte|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ESYT1 USP9Y CCDC88A TLR3 NAV1

1.05e-041701225ff68600b945b3a5437b14e5411b3db800d0ccbe5
ToppCellControl-B_naive-1|Control / disease group and sub_cluster of B and Plasma cells(res = 0.5)

IL24 SNU13 MACF1 CEP295 ARHGAP45

1.08e-041711225d18855b24aadea38fd1e4592f945cf15b85e05f1
ToppCellE16.5-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-SCMF-SCMF_mature|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SYNE1 DZIP1 SMYD4 P2RY14 CCDC157

1.21e-0417512251d8aab491dcc27ea5dbfb6462d18ee280b21a05e
ToppCellE16.5-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-SCMF|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SYNE1 DZIP1 SMYD4 P2RY14 CCDC157

1.21e-041751225427a7ee92fe16a90625946492062d37aa0f7235b
ToppCelldroplet-Heart-nan-3m|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ROCK2 TPR CCDC88A CEP112 MACF1

1.24e-041761225749b47eac5436fa34e0d243ffbc6f1897f4e431e
ToppCellfacs-Lung-18m-Hematologic-Lymphocytic_NK_ILC-Alox5+_lymphocyte-Alox5+_lymphocyte|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

TRAF1 KCNQ5 CDK5RAP2 P2RY14 CWF19L1

1.27e-041771225b7cfa3776f58377e35830780650d236b5cceecee
ToppCellfacs-Lung-18m-Hematologic-Lymphocytic_NK_ILC-Alox5+_lymphocyte|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

TRAF1 KCNQ5 CDK5RAP2 P2RY14 CWF19L1

1.27e-0417712251730e640986e50943bd781b7d949bcc5b7c12dde
ToppCellE16.5-Immune-Immune_Myeloid-Megakaryocyte/Platelet-Megakaryocyte/Platelet|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SYNE1 CDH23 MMRN1 UBA7 ARHGAP45

1.27e-04177122584591e28482ab62a5ef41e61043eb64912766356
ToppCellE16.5-Immune-Immune_Myeloid-Megakaryocyte/Platelet-Megakaryocyte/Platelet-Megakaryocyte/Platelet_mature|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SYNE1 CDH23 MMRN1 UBA7 ARHGAP45

1.27e-0417712254bc100062891d07cacd10ffba38966cc6302c92f
ToppCellE16.5-Immune-Immune_Myeloid-Megakaryocyte/Platelet|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SYNE1 CDH23 MMRN1 UBA7 ARHGAP45

1.27e-0417712259f3a2adb9cd4f0a059afc87b6e377a9702154bb1
ToppCellICU-NoSEP-Myeloid-cDC1|ICU-NoSEP / Disease, Lineage and Cell Type

ENOX1 PLEKHA6 TLR3 NAV1 P2RY14

1.27e-04177122533cd2c183ee8b597012efcbcae72131ac6beaf4e
ToppCellASK454-Endothelial-Lymphatic|ASK454 / Donor, Lineage and Cell class of Lung cells from Dropseq

ANGPT2 MMRN1 KCNN3 TAF5L KIF17

1.34e-041791225fd84a79f76a01c0377dff5b20016b004d369f96f
ToppCellfacs-Marrow-T-cells-3m-Hematologic|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TANK CDH23 UFL1 ARFGEF3 CREB3L2

1.41e-04181122557f0cc749ae8b6a3d77e2af31f9a6e4739c57049
ToppCellfacs-Marrow-T-cells-3m-Hematologic-hematopoietic_stem_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TANK CDH23 UFL1 ARFGEF3 CREB3L2

1.41e-041811225d01b35cc2fc57991a35be6a06cb7351fbabd9a11
ToppCellControl-APC-like-Dendritic_cells|Control / group, cell type (main and fine annotations)

ENOX1 CCDC88A SNX8 NAV1 P2RY14

1.49e-0418312258f9c8e2436f18ea7c265b08e4e149e19cb513a16
ToppCellControl-APC-like|Control / group, cell type (main and fine annotations)

ENOX1 CCDC88A SNX8 NAV1 P2RY14

1.49e-041831225c313ac72cc9fa1583456d452393f61f0a4ca33a8
ToppCellLPS_only|World / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

TRAF1 TANK WTAP VPS13B TP53BP2

1.56e-041851225a72ccb147ca505880e2da8f6a70b9d570464a691
ToppCell10x_3'_v3-tissue-resident_(10x_3'_v3)-myeloid-myeloid_dendritic-CD1c-positive_myeloid_dendritic_cell|tissue-resident_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

IL24 TRAF1 WTAP SNX8 NAV1

1.60e-0418612250dce13e15c3bf32610bf2dad31253b52a39cff87
ToppCellnormal_Lung-Myeloid_cells-pDCs|normal_Lung / Location, Cell class and cell subclass

UFL1 CCDC88A KCNQ5 CEP112 KIF17

1.64e-041871225d36751372fd40a46441f07735c9c3c5dcb503f24
ToppCell367C-Lymphocytic-NK_cells-NK_cell_B0|NK_cells / Donor, Lineage, Cell class and subclass (all cells)

TRAF1 CDK5RAP2 CWF19L1 DOP1B CREB3L2

1.64e-041871225816d37a70f7ec382a268fe828b3dfe737a36a4bf
ToppCell(04)_Pre-ciliated-(3)_72hpi|(04)_Pre-ciliated / shred by cell type and Timepoint

CNTROB CEP164 VPS13D CFAP57 SPAG17

1.69e-041881225f911dc61b008b60aaa2a1e9354085f480a669e2c
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast-|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

SYNE1 KIF7 TENM3 LRFN5 CREB3L2

1.77e-0419012251121eb607a984c59fbffe7220837fc178745aa55
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

SYNE1 KIF7 TENM3 LRFN5 CREB3L2

1.77e-041901225048b581e3f7ea9fc2f87c0532974bba85c7292c2
ToppCellPND10|World / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

HOOK3 NAV1 MACF1 P2RY14 GOLGA4

1.77e-041901225d67e2814047c8df2ae4b7bc8be9539f5df6ecef2
ToppCelldroplet-Large_Intestine-COLON_PROXIMAL|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TPR USP34 DHX36 APOB IQGAP1

1.81e-04191122560c986d2dcbc19d9338c03da6cb5e1d92fd48f8e
ToppCellDendritic_Cells-Myositis-ILD_01|World / lung cells shred on cell class, cell subclass, sample id

SLC12A5 BRD8 NAV1 MAFB ARHGAP45

1.81e-041911225b51c8ff1279581088557bb36760c70209c77148c
ToppCelldroplet-Large_Intestine-COLON_PROXIMAL-30m-Epithelial|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TPR USP34 APOB IQGAP1 GOLGA4

1.81e-04191122509db184cb90fe282a14474d7217068c58092c6f8
ToppCelldroplet-Large_Intestine-COLON_PROXIMAL-30m|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TPR USP34 DHX36 APOB IQGAP1

1.81e-041911225973117730d6ba5f127e7a0bfabfd0ff2ca7ac131
ToppCellTCGA-Prostate-Primary_Tumor-Prostate_Adenocarcinoma-Acinar_Adenocarcinoma-6|TCGA-Prostate / Sample_Type by Project: Shred V9

TNPO1 USP34 ARFGEF3 GCC2 VPS13B

1.90e-041931225abd71b2cf667ef2b1c4d88acd0c1dd19a12ff659
ToppCellsevere-low-quality_cells|severe / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

SYNE1 USP9Y ELFN1 MACF1 VPS13B

1.90e-0419312259337bc93e3904c7fc7c93c328518bcd6453b1e8c
ToppCellPosterior_cortex-Neuronal|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

DOCK3 NBEA SLC12A5 ARFGEF3 GCC2

1.90e-041931225b4989e3436e84dbec3789b46057e0f7a0ebf09d4
ToppCellDendritic_Cells|World / lung cells shred on cell class, cell subclass, sample id

BRD8 NAV1 P2RY14 MAFB ARHGAP45

1.90e-0419312257792eb6e247af2d7a8f80476f37dcd880922d625
ToppCellControl-Lymphoid-pDC|Lymphoid / Condition, Lineage and Cell class

NBEA MMRN1 CCDC88A P2RY14 KIF17

1.95e-0419412255f95a5a35f73222dbe2ca52cc580f4774f641403
ToppCell3'-Broncho-tracheal-Immune_Myeloid-Myeloid_macrophage-lung_macrophage|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

IQGAP1 ARHGAP4 CCDC88A P2RY14 MAFB

1.95e-04194122548c37251518f96524807b5bd1bbc2820637666ad
ToppCell3'-Broncho-tracheal-Immune_Myeloid-Myeloid_macrophage-lung_macrophage-Interstitial_macrophage_perivascular-Interstitial_macrophage_perivascular_L.1.2.1.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

IQGAP1 ARHGAP4 CCDC88A P2RY14 MAFB

1.95e-0419412257b6a34d1f8922b71dcc931421666c1822cec8345
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic-i_Gaba_3|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ENOX1 TENM3 ELFN1 MAFB ECE2

1.95e-041941225e5990880961d2469759ce4b3b20ae93ace3ebd1f
ToppCell10x5'-bone_marrow-Myeloid_Dendritic|bone_marrow / Manually curated celltypes from each tissue

ENOX1 NUDT17 CCDC88A P2RY14 KIF17

1.95e-041941225768271ae45ff9f6aa3cd9b0ed15fa3caaa68a7b0
ToppCell3'-Broncho-tracheal-Immune_Myeloid-Myeloid_macrophage-lung_macrophage-Interstitial_macrophage_perivascular|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

IQGAP1 ARHGAP4 CCDC88A P2RY14 MAFB

1.95e-041941225435406ebe626c702f7d5a99a3d68ee85aa09be95
ToppCell368C-Myeloid-Macrophage-M2-like_Macrophage_(MARCO_negative)|Macrophage / Donor, Lineage, Cell class and subclass (all cells)

SYNE1 SLC12A5 P2RY14 MAFB ARHGAP45

1.95e-04194122558046894446cb250814252a23f60fdd59c114d77
ToppCellIPF-Multiplet-Multiplet|IPF / Disease state, Lineage and Cell class

SYNE1 NBEA ARFGEF3 CEP112 SPAG17

2.00e-041951225fce0c29574bb7aab181b9c00feb42681e285d1f2
ToppCellIPF-Multiplet|IPF / Disease state, Lineage and Cell class

SYNE1 NBEA ARFGEF3 CEP112 SPAG17

2.00e-041951225eacc0449ae6f3ad8002268cd061467684c6fb9a7
ToppCelldroplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NBEA ZC3H3 IQGAP1 MACF1 GOLGA4

2.00e-0419512253e519cffa6144a62b06124642a14c9ff39b76554
ToppCell343B-Myeloid-Macrophage-M2-like_Macrophage_(MARCO_negative)|Macrophage / Donor, Lineage, Cell class and subclass (all cells)

SYNE1 E2F1 SLC12A5 MAFB ARHGAP45

2.00e-04195122567b05a0cd2ca9924eca81a92cc6330eecb9d963c
ToppCelldroplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NBEA ZC3H3 IQGAP1 MACF1 GOLGA4

2.00e-0419512257796ea9247f4c63762f0de8490fed08b9717fa23
ToppCellMid-temporal_gyrus_(MTG)-Neuronal|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SYNE1 NBEA SLC12A5 KCNQ5 LRFN5

2.05e-041961225676c56b44ac29f7baecb62f49bb8597cc74c0a88
ToppCellCOVID-mDC2|COVID / Condition, Cell_class and T cell subcluster

BLOC1S6 CCDC88A NAV1 P2RY14 KIF17

2.05e-041961225bb13926bb664be917017edb0ce7f184abe31744b
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW09-Macroglial-Glia_progenitor_cell|GW09 / Sample Type, Dataset, Time_group, and Cell type.

SPTBN2 FASTKD2 NUDT17 TENM3 CREB3L2

2.05e-0419612257be50b9156394dea44d7b8b476d4dd516abfafae
ToppCellCOVID-mDC2-|COVID / Condition, Cell_class and T cell subcluster

BLOC1S6 CCDC88A NAV1 P2RY14 KIF17

2.05e-0419612256d02a4c5c19be7e036150cf945585cf5a773bc87
ToppCell367C-Myeloid-Macrophage-M2-like_Macrophage_(MARCO_negative)|Macrophage / Donor, Lineage, Cell class and subclass (all cells)

SYNE1 SLC12A5 P2RY14 MAFB ARHGAP45

2.05e-041961225e8c4eeb4b6c6d9bccca2adb942d4cfbaab39636c
ToppCell3'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SYNE1 CEP290 KCNN3 CFAP57 SPAG17

2.09e-04197122574a2c6cb8fcfe53dd9a2b36492a16c58f38e51c9
ToppCellH1299-infected-SARSCoV2|infected / Cell line, Condition and Strain

CEP290 CEP164 CCDC88A CDK5RAP2 CEP295

2.09e-0419712250fa3e4cf93e77d78b1f97b906c5b13ca741ae17e
ToppCellmild-pDC|mild / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

CDH23 NUDT17 CCDC88A P2RY14 KIF17

2.09e-04197122515230a54fa5903dd728de1a0ad633bd2d2c7a04d
ToppCellIPF-Stromal-Myofibroblast|Stromal / Disease state, Lineage and Cell class

ANGPT1 CDH23 TENM3 MACF1 VPS13B

2.09e-041971225f304d42fc4936fe20996e07c8dccc698a6e5e5ef
ToppCellsystemic_lupus_erythematosus-flare|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

TPR SYNE1 GCC2 MACF1 ARHGAP45

2.14e-0419812254c93ee921d56132d80832d8e94563f32ccf13bbc
ToppCellSomatosensory_Cortex_(S1)-Neuronal|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SYNE1 NBEA SLC12A5 KCNQ5 LRFN5

2.14e-041981225c01091ef18e096d792ea2a7a715764a5b215355f
ToppCellprimary_auditory_cortex_(A1C)-Neuronal|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SYNE1 NBEA SLC12A5 KCNQ5 LRFN5

2.14e-0419812256d18b45eda4014759e6dd282d78ffd28df8a6044
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SYNE1 NBEA SLC12A5 KCNQ5 LRFN5

2.14e-0419812254ca5ff320905ab4ff60ed90a5522227c782142a6
ToppCellParenchymal-NucSeq-Immune_Myeloid-Dendritic_cell-DC_plasmacytoid|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

NUDT17 KIF20B CCDC88A VAMP1 P2RY14

2.14e-041981225c64238379798ae6b292cc1914d60548c88e652de
ToppCell(10)_Ciliated-(2)_GFP_FOXI1|(10)_Ciliated / shred by cell type by condition

CEP290 VPS13D GCC2 SPAG17 GOLGA4

2.19e-04199122561b1ed2db71b96157b92b7535d1955a4033098da
ToppCell(09)_Interm._secr.>cil.-(2)_GFP_FOXI1|(09)_Interm._secr.>cil. / shred by cell type by condition

TPR CEP290 IQGAP1 GCC2 GOLGA4

2.19e-041991225fc680f85ebd3bab4c72876a19a461b0afb5f51ce
ToppCell(01)_IL1RL1+-(2)_GFP_FOXI1|(01)_IL1RL1+ / shred by cell type by condition

ROCK2 TPR CCDC88A GCC2 GOLGA4

2.19e-041991225a2f7d0cabf35b80fe239fae34a77bf9344d5d743
ToppCellControl_saline-Mesenchymal_fibroblastic|Control_saline / Treatment groups by lineage, cell group, cell type

ANGPT1 SYNE1 PLEKHA6 TEX15 MACF1

2.25e-04200122564ae5cf6cb4fc94cf1052abd82648f6b8e6445fe
ToppCellControl_saline-Endothelial-Endothelial-FOXM1|Control_saline / Treatment groups by lineage, cell group, cell type

E2F1 CNTROB KIF20B CCDC88A CDK5RAP2

2.25e-0420012259bbc7b5561151f6ff65f40b3226271def732e5d9
ToppCellTCGA-Bile_Duct-Primary_Tumor-Cholangiocarcinoma-Intrahepatic|TCGA-Bile_Duct / Sample_Type by Project: Shred V9

ATF7 ESYT1 SLC30A5 MLLT1 RNF41

2.25e-0420012251fa8422fd820d21e285a7e7c4c6fbd8b7277d2af
ToppCellNeuronal|World / cells hierarchy compared to all cells using T-Statistic

SYNE1 NBEA SLC12A5 KCNQ5 LRFN5

2.25e-04200122548d801219bc771d6c7e151dc88ca4c179988de85
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW13-Mesenchymal-Mesoderm|GW13 / Sample Type, Dataset, Time_group, and Cell type.

LRRC37A2 NUDT17 MICALL1 SMYD4 TAF5L

2.25e-0420012250f4b8b0868bda406fe6bf01d1b722510fdfd0168
ToppCellParenchymal-NucSeq-Immune_Lymphocytic-NK-ILC-T_NK-ILC|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

SALL4 MMRN1 KCNQ5 ELFN1 SNU13

2.25e-04200122549ad6e2337886367fbfa2a7c7366687b701ddf39
ToppCellControl_saline-Mesenchymal_fibroblastic-Fibroblasts|Control_saline / Treatment groups by lineage, cell group, cell type

ANGPT1 SYNE1 PLEKHA6 TEX15 MACF1

2.25e-042001225a1fc74c1b27e104895910bc7cdce7ba33d30df7e
ToppCellControl_saline-Mesenchymal_fibroblastic-Fibroblasts-MatrixFB|Control_saline / Treatment groups by lineage, cell group, cell type

ANGPT1 SYNE1 PLEKHA6 TEX15 MACF1

2.25e-042001225bd8cf33502adea320e91ca2af14e1911d88ad374
Drug(-) -Levobunolol hydrochloride [27912-14-7]; Down 200; 12.2uM; MCF7; HT_HG-U133A

TPR SIKE1 SPTBN2 CEP290 VPS13D CCDC88A SLC30A5 CEP250

1.01e-0519412284134_DN
DrugTranylcypromine hydrochloride [1986-47-6]; Down 200; 23.6uM; MCF7; HT_HG-U133A

FASTKD2 PLEKHA6 IDUA WDR59 PRKD3 UBA7 CEP250 ARHGEF2

1.05e-0519512282264_DN
DrugGSK-3 Inhibitor IX; Up 200; 0.5uM; PC3; HT_HG-U133A

IL24 MAN2A2 CEP290 ZNF236 IDUA CEP112 CHPF2 MAST3

1.05e-0519512287048_UP
Drugfluphenazine dihydrochloride; Down 200; 10uM; HL60; HT_HG-U133A

ROCK2 DZIP1 MFN1 ARHGAP4 VPS13D SLC30A5 MAFB MAST3

1.09e-0519612281178_DN
DrugAlfuzosin hydrochloride [81403-68-1]; Up 200; 9.4uM; HL60; HG-U133A

TPR USP34 TANK UFL1 MICALL1 VPS13D MAFB CHPF2

1.09e-0519612281586_UP
DrugMidecamycin [35457-80-8]; Down 200; 5uM; MCF7; HT_HG-U133A

TANK CEP290 MED14 VPS13D MACF1 MAFB TAF5L ARHGAP45

1.17e-0519812285345_DN
DrugEstriol [50-27-1]; Down 200; 13.8uM; MCF7; HT_HG-U133A

USP34 E2F1 ZC3H3 CCDC88A CDK5RAP2 MAFB ARHGAP45 GOLGA1

1.22e-0519912283563_DN
Drugdiethyl acetylenedicarboxylate

SYNE1 SPAG17

2.85e-0521222CID000069803
DrugRitodrine hydrochloride [23239-51-2]; Up 200; 12.4uM; HL60; HT_HG-U133A

IL24 ROCK2 TPR WDR59 PRKD3 MAFB MAST3

5.74e-0518212271280_UP
DrugAdenosine 5'-monophosphate monohydrate [18422-05-4]; Up 200; 11uM; HL60; HG-U133A

SIKE1 MICALL1 SLC30A5 VAMP1 MACF1 MAFB GOLGA1

7.28e-0518912271622_UP
DrugImipenem [74431-23-5]; Down 200; 13.4uM; MCF7; HT_HG-U133A

USP34 PLEKHA6 ZC3H3 MICALL1 PLEKHO2 MAFB VPS13B

8.04e-0519212272873_DN
DrugPindolol [13523-86-9]; Down 200; 16.2uM; PC3; HT_HG-U133A

ROCK2 SYNE1 WDR59 TENM3 CDK5RAP2 TAF5L ARHGEF2

8.04e-0519212274496_DN
Drugbis(dicyclohexylphosphino)methane

UBA7 SPAG17

8.51e-0531222CID000618458
DrugAcacetin [480-44-4]; Down 200; 14uM; MCF7; HT_HG-U133A

PLEKHA6 ZNF236 SLC30A5 TENM3 PLEKHO2 CEP250 MAST3

8.86e-0519512273942_DN
DrugOxymetazoline hydrochloride [2315-02-8]; Down 200; 13.4uM; MCF7; HT_HG-U133A

ZNF236 IDUA WDR59 PRKD3 SLC30A5 CEP250 MAST3

8.86e-0519512272278_DN
DrugCondelphine [7633-69-4]; Down 200; 8.8uM; HL60; HT_HG-U133A

TPR SIKE1 CEP290 DZIP1 ZNF236 MAFB CWF19L1

9.15e-0519612272976_DN
DrugHydrastine hydrochloride [5936-28-7]; Down 200; 9.6uM; MCF7; HT_HG-U133A

E2F1 PLEKHA6 ZC3H3 MICALL1 PRKD3 CEP250 MAST3

9.15e-0519612272889_DN
DrugGuanabenz acetate [23256-50-0]; Up 200; 13.8uM; PC3; HG-U133A

CEP290 IQGAP1 MICALL1 VPS13D PLEKHO2 CDK5RAP2 RNF41

9.15e-0519612271961_UP
DrugScopolamin-N-oxide hydrobromide [6106-81-6]; Down 200; 10uM; MCF7; HT_HG-U133A

MED14 FASTKD2 WDR59 MICALL1 VPS13D CHPF2 VPS13B

9.44e-0519712275436_DN
DrugHydroxyzine dihydrochloride [2192-20-3]; Down 200; 9uM; PC3; HG-U133A

IL24 E2F1 KIF20B PLEKHO2 VAMP1 RNF41 ARHGEF2

9.44e-0519712271941_DN
DrugMeclocycline sulfosalicylate [73816-42-9]; Down 200; 5.8uM; MCF7; HT_HG-U133A

TPR USP34 TANK CEP290 PLEKHA6 MICALL1 MAFB

9.44e-0519712273277_DN
DrugCarbetapentane citrate [23142-01-0]; Up 200; 7.6uM; MCF7; HT_HG-U133A

ANGPT2 SYNE1 UBA7 TENM3 MAFB CROCC VPS13B

9.75e-0519812272623_UP
DrugOxprenolol hydrochloride [6452-73-9]; Down 200; 13.2uM; PC3; HT_HG-U133A

ROCK2 MAN2A2 E2F1 VPS13D PLEKHO2 RNF41 DOP1B

9.75e-0519812275871_DN
Druggenistein; Up 200; 10uM; MCF7; HT_HG-U133A

IL24 USP34 SIKE1 ZNF236 CCDC88A CEP250 VPS13B

9.75e-0519812275595_UP
DrugAmoxapine [14028-44-5]; Down 200; 12.8uM; HL60; HG-U133A

ROCK2 MAN2A2 ZC3H3 VPS13D CCDC88A MACF1 CHPF2

9.75e-0519812272013_DN
DrugSulfamethoxazole [723-46-6]; Down 200; 15.8uM; PC3; HT_HG-U133A

TPR TANK CEP290 CDK5RAP2 CWF19L1 GOLGA1 MAST3

9.75e-0519812277366_DN
DrugChenodiol [474-25-9]; Up 200; 10.2uM; MCF7; HT_HG-U133A

DMTF1 USP34 TANK MED14 CCDC88A ARHGAP45 MAST3

9.75e-0519812277433_UP
DrugCefixime [79350-37-1]; Down 200; 8.8uM; MCF7; HT_HG-U133A

TANK CEP290 MED14 ZC3H3 MFN1 SLC12A5 ARHGEF2

1.01e-0419912274390_DN
Drug2-Chloropyrazine [14508-49-7]; Down 200; 35uM; HL60; HT_HG-U133A

TRAF1 TEX15 CEP164 VPS13D SLC30A5 MACF1 KIF17

1.01e-0419912276148_DN
DrugFenspiride hydrochloride [5053-08-7]; Up 200; 13.4uM; PC3; HT_HG-U133A

SPTBN2 TEX15 IDUA CEP164 UBA7 TENM3 VAMP1

1.01e-0419912277298_UP
Drug(-)-Eseroline fumarate salt [104015-29-4]; Down 200; 12uM; PC3; HT_HG-U133A

USP34 MAN2A2 CCDC88A SLC30A5 PLEKHO2 RNF41 VPS13B

1.01e-0419912277267_DN
DrugMephenesin [59-47-2]; Up 200; 22uM; PC3; HT_HG-U133A

IL24 ENOX1 DZIP1 CEP164 PLEKHO2 ARHGAP45 DOP1B

1.01e-0419912277374_UP
DrugCanavanine sulfate monohydrate (L,+) [206996-57-8]; Up 200; 13.6uM; HL60; HT_HG-U133A

ROCK2 TRAF1 NBEA TEX15 VPS13D KIF17 VPS13B

1.04e-0420012272141_UP
DiseaseDuane Retraction Syndrome, Type 2

SALL4 MAFB

4.83e-0531192C0751083
DiseaseDuane Retraction Syndrome, Type 3

SALL4 MAFB

4.83e-0531192C0751084
DiseaseType 1 Duane Retraction Syndrome

SALL4 MAFB

4.83e-0531192C0994516
DiseaseDuane retraction syndrome (is_implicated_in)

SALL4 MAFB

4.83e-0531192DOID:12557 (is_implicated_in)
DiseaseOkihiro Syndrome

SALL4 MAFB

4.83e-0531192C1623209
Diseasegastric ulcer (biomarker_via_orthology)

ANGPT1 ANGPT2 IDUA

8.07e-05211193DOID:10808 (biomarker_via_orthology)
DiseaseDuane Retraction Syndrome

SALL4 MAFB

1.60e-0451192C0013261
Diseasepost-traumatic stress disorder symptom measurement

SYNE1 LRRC37A2 NBEA UBA7

3.45e-04821194EFO_0008535
DiseaseSpinocerebellar Ataxia Type 4

PLEKHG4 SPTBN2 CWF19L1

3.81e-04351193C0752122
DiseaseMalignant neoplasm of breast

IL24 TANK SYNE1 LRRC37A2 MED14 E2F1 NUDT17 MICALL1 HOOK3 LRRC37A MACF1 VPS13B TP53BP2

4.04e-04107411913C0006142
DiseaseColorectal Carcinoma

SYNE1 SPTBN2 APOB MFN1 SLC12A5 FANCG KCNQ5 SNX8 P2RY14 SPAG17

5.66e-0470211910C0009402
Diseasepolymeric immunoglobulin receptor measurement

IL24 CHPF2

7.11e-04101192EFO_0008267
Diseaseendometrial adenocarcinoma (is_marker_for)

ANGPT1 ANGPT2

8.66e-04111192DOID:2870 (is_marker_for)
DiseaseRenal dysplasia and retinal aplasia (disorder)

CEP290 CEP164

1.04e-03121192C0403553
DiseaseEmery-Dreifuss muscular dystrophy (implicated_via_orthology)

SYNE1 HOOK3

1.04e-03121192DOID:11726 (implicated_via_orthology)
DiseaseCiliopathies

CEP290 CDH23 CEP164 KIF7

1.04e-031101194C4277690
Diseasemammographic density measurement

NBEA GVINP1 SPAG17

1.09e-03501193EFO_0005941
Diseasebone fracture

DMTF1 MRPL28 IDUA MINDY4

1.12e-031121194EFO_0003931
DiseasePolydactyly

CEP290 SALL4 CEP164 KIF7

1.31e-031171194C0152427
DiseaseMammary Carcinoma, Human

IL24 TANK SYNE1 LRRC37A2 E2F1 NUDT17 LRRC37A TP53BP2

1.33e-035251198C4704874
DiseaseMammary Neoplasms, Human

IL24 TANK SYNE1 LRRC37A2 E2F1 NUDT17 LRRC37A TP53BP2

1.33e-035251198C1257931
DiseaseMammary Neoplasms

IL24 TANK SYNE1 LRRC37A2 E2F1 NUDT17 LRRC37A TP53BP2

1.36e-035271198C1458155
Diseaseisoleucine measurement

TNPO1 DDX19B CFAP57

1.52e-03561193EFO_0009793
DiseaseBreast Carcinoma

IL24 TANK SYNE1 LRRC37A2 E2F1 NUDT17 LRRC37A TP53BP2

1.55e-035381198C0678222
Diseasecortical thickness

ANGPT1 SPTBN2 IDUA KIF20B MICALL1 VPS13D CCDC88A CEP112 NAV1 CDK5RAP2 MACF1 CFAP57

1.82e-03111311912EFO_0004840
DiseaseBardet-Biedl syndrome 1 (disorder)

CEP290 KIF7

2.11e-03171192C2936862
Diseaserefractive error

NBEA CNTROB RD3L KCNQ5 LRFN5 ECEL1

2.12e-033261196MONDO_0004892
Diseasehistidine measurement

TNPO1 SNX8 MAFB

2.43e-03661193EFO_0009769
Diseasealkaline phosphatase measurement

USP34 ATF7 APOB SLC12A5 SLC30A5 GCC2 MACF1 MAFB CHPF2 KIF17 CREB3L2

2.72e-03101511911EFO_0004533
DiseaseFamilial aplasia of the vermis

CEP290 KIF7

2.92e-03201192cv:C0431399
Diseaseprogranulin measurement

CDH23 LRFN5

3.53e-03221192EFO_0004625
Diseaseotitis media (implicated_via_orthology)

SALL4 IDUA

3.53e-03221192DOID:10754 (implicated_via_orthology)
Diseasenephrosis (biomarker_via_orthology)

ANGPT1 ANGPT2

3.53e-03221192DOID:2527 (biomarker_via_orthology)
Diseaseplatelet component distribution width

TANK ANGPT1 SYNE1 MICALL1 BRD8 PLEKHO2 GCC2 MACF1 MAFB

3.56e-037551199EFO_0007984
Diseaseunipolar depression, bipolar disorder

DMTF1 ENOX1 SYNE1 LRFN5

3.73e-031561194EFO_0003761, MONDO_0004985

Protein segments in the cluster

PeptideGeneStartEntry
ELEEVLQVNSLIQTQ

ESYT1

776

Q9BSJ8
QQINSTIVDLRLNEN

ELFN1

56

P0C7U0
QRDVLEQIQQFLATQ

BRD8

801

Q9H0E9
VINSIKQEIVNRVQN

CREBRF

566

Q8IUR6
VSLQNLIVRDIANQE

ARHGEF2

521

Q92974
EQVNISQFSQLIEIL

GVINP1

626

Q7Z2Y8
EAQVLNQTTRLELQL

ANGPT2

146

O15123
ELINVNSQRKQQLVE

CEP112

736

Q8N8E3
QVLNQTSRLEIQLLE

ANGPT1

151

Q15389
NIQLSNEVTLLRNEV

ATF7

371

P17544
QVQQLEAQVQLLVGR

CCDC157

401

Q569K6
SNRRENSVQVVIQVL

CDH23

2486

Q9H251
TQIQILQNEQLDEIS

DMTF1

106

Q9Y222
QEVQTAILRVDQLSQ

PPP1R13B

226

Q96KQ4
QIEAQQQLLATKEQR

TP53BP2

141

Q13625
VQEEVKLRQQLLSQN

CDK5RAP2

1536

Q96SN8
VITLIRSNQQLENDL

IQGAP1

896

P46940
ALLTNVDQIVQETQR

LRFN5

701

Q96NI6
NALVLQTQQEIIENL

MFN1

466

Q8IWA4
QLIQLINVDEVNQIV

CHRNA1

56

P02708
TALRQIQEVIRQSDQ

ARHGAP45

486

Q92619
TQLIQQVEQLKQEVS

MAFB

271

Q9Y5Q3
QELQALIQQLSIDLQ

GOLGA1

266

Q92805
DQFEIQLTQQLQSLI

LRRC37A2

1471

A6NM11
DQFEIQLTQQLQSLI

LRRC37A

1471

A6NMS7
LLVISQESQQQLQAR

NUDT17

186

P0C025
AQLRQLTEEQNTLNI

GOLGA4

1276

Q13439
VTNERDQALQLQVLN

MMRN1

886

Q13201
ESINLQQEALQRIIS

FSD1L

31

Q9BXM9
IQRLRDQIQEQEQVT

CFAP57

1211

Q96MR6
LDSNVLVQRNNLEIV

DOP1B

236

Q9Y3R5
SVQNLIRSTEELNIQ

KCNQ5

831

Q9NR82
SLIVNEEVQNLISNI

FSIP2

881

Q5CZC0
FITQAQEQQIELLEI

CWF19L1

436

Q69YN2
QQVLELEIQLANITV

ECE2

346

P0DPD6
AQILALQRQTVSLQE

CCDC88A

1081

Q3V6T2
EQRVQVQVVERAQQV

FLOT1

251

O75955
LRQQQQQLLSAIIEA

KCNN3

681

Q9UGI6
TQNQRIKELINIIDQ

KIF20B

761

Q96Q89
AQQLLTLQNQVARLE

KIF7

486

Q2M1P5
VVRTQETQEIRTLNN

KRT78

106

Q8N1N4
LSQVQRLITNVESQL

KRT33A

311

O76009
QESQLRNEVAILQNL

PRKD3

616

O94806
QLKQQIQSIQQSIER

SNU13

111

P55769
QELVTLIEQRNAIIN

MICALL1

786

Q8N3F8
IQRSLERVLETQEQQ

FANCG

96

O15287
QLQTQLEQLQEETFR

HOOK3

246

Q86VS8
QEILQVEQQLANITV

ECEL1

311

O95672
RLEQDQTTAQLQVQK

MACF1

5701

Q9UPN3
QRIIQQETLQLINSN

MED14

1221

O60244
AEQAISVRQQVVLEN

EXOSC10

761

Q01780
QTIIVVLENVQRNLK

APOB

2086

P04114
QRQIQQLEAQVVVLE

CROCC

1921

Q5TZA2
LTQDLRQLQESEQQL

E2F1

206

Q01094
IQVVENKNQELRSLI

DOCK3

1511

Q8IZD9
IARRQVEILNAQQQS

CEP290

1161

O15078
REEQIVQLLNSVQAK

DHX36

91

Q9H2U1
TLQLRQRQENTIIEN

ARFGEF3

171

Q5TH69
LQLVLEEQVLALQQQ

CEP250

16

Q9BV73
LLLSQREQEIVVLQQ

CEP250

1771

Q9BV73
IRSNLVDNTNQVEVL

DDX19B

66

Q9UMR2
TRLENQNLLIQVEEV

GCC2

871

Q8IWJ2
ITSARLLQQEVLQNV

IL24

86

Q13007
ALSQQAEVIVRQLQE

CCHCR1

86

Q8TD31
QNQVVLLDTLEQEIS

BLOC1S6

76

Q9UL45
SILEQEKVVAQQIRQ

IDUA

271

P35475
QISVLQNRIEQLEQL

MAN2A2

46

P49641
RNQIQQVFVERDILT

MAST3

406

O60307
ERNVLQQIVNLIEET

MLLT1

511

Q03111
TILVLQQQLKETRQQ

WTAP

221

Q15007
ENLTILQEQSQIQRV

CEP295

1161

Q9C0D2
VVQQQQTRIAELEKT

RNF41

141

Q9H4P4
LQQIQLTEQIRIQVN

SALL4

226

Q9UJQ4
VLTVALVNQDRENNI

ENOX1

541

Q8TC92
SLQTRVLELQQQLAV

CNTROB

206

Q8N137
EVLENTNRTLLQQLQ

CREB3L2

341

Q70SY1
QLLVLVRVDQDQNVV

SLC12A5

696

Q9H2X9
VDQQQVLARLQLLEQ

KIF17

736

Q9P2E2
TVQNVLDLRQNLEET

NAV1

261

Q8NEY1
VIEQLQTTQTIQDIL

TAF5L

136

O75529
VQTERQRIQTEFDQL

TRIM34

176

Q9BYJ4
NRRLQQTQAQVEEVV

VAMP1

31

P23763
VSRLQDLQQQVRVAQ

SMYD4

651

Q8IYR2
QLESRIVEQENAIQT

SNX8

371

Q9Y5X2
LQLIQALQNEVVSQA

SYNE1

1696

Q8NF91
EQQLAAQLVTLQNEL

TMEM191B

171

P0C7N4
ILQVVTELLQLNNND

NBR1

946

Q14596
QSNQRIQALELVQTL

PLEKHG4

441

Q58EX7
QNTILVQTLLRVTQE

FASTKD2

246

Q9NYY8
RQITDLVDQSIQINA

NBEA

2666

Q8NFP9
ILLSQENTQIRDLQQ

SIKE1

71

Q9BRV8
IREQQEQLSLQQTII

TANK

41

Q92844
NIILTNQSVREVTQI

P2RY14

156

Q15391
VTEQRQLEVLCSQVQ

RD3L

76

P0DJH9
QEQNELIITQRQQIK

DZIP1

426

Q86YF9
LQGRVNQLVQTLIVQ

ARHGAP4

676

P98171
QDILQQINEINTLVG

SPAG17

71

Q6Q759
LESQVDLLQAQSQQL

CEP164

1011

Q9UPV0
SEIEQLQAQIRNLTV

CHPF2

331

Q9P2E5
SLQNQLINIRVELSQ

PLEKHA6

591

Q9Y2H5
LERQVQLSQGQNVVI

ZC3H3

111

Q8IXZ2
VQQAIEQNLDSIILV

TLR3

836

O15455
LANQQEQIRLTIDTT

MINDY4

706

Q4G0A6
IEQTIVTLNDRQLAN

SPTBN2

321

O15020
SQELLAQLNRAVQVV

UBA7

91

P41226
ARNLQEQTVQLQSEL

TPR

1511

P12270
QVEQQVKELQNRLSQ

SOGA1

861

O94964
QISTEKVNQLQRQLD

ROCK2

551

O75116
SLEQRVVELQQTLAQ

TRAF1

231

Q13077
DNNVVLQITENRQVR

TENM3

1361

Q9P273
VAELIQQLQQQALSE

MRPL28

231

Q13084
IQQNNILSIVLQDSL

USP9Y

391

O00507
TIQRTVQQKLEQLNQ

TNPO1

36

Q92973
NQGNQIVSLIIIQEE

ZSCAN4

211

Q8NAM6
LQQEFSLINVQIRNV

WDR59

391

Q6PJI9
RVVNNVNIVINNLIL

VPS13B

146

Q7Z7G8
QVTSDVLEQRIVQQV

SLC30A5

696

Q8TAD4
QLSITVGINQDILQQ

ZNF236

381

Q9UL36
QAVEQLRQATQVLQE

PLEKHO2

446

Q8TD55
LINLVIAQVQVLRDQ

USP34

66

Q70CQ2
QSINENLVLQSIELE

TEX15

661

Q9BXT5
TDLQILSTQVEQRLN

WDR87

1021

Q6ZQQ6
RVNIVDLQQVINVDL

UFL1

76

O94874
QVISLQVNNLDIILN

VPS13D

1101

Q5THJ4