Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionpolyol transmembrane transporter activity

AQP7B AQP7P3 AQP7 SLC5A1

6.00e-07131104GO:0015166
GeneOntologyMolecularFunctionwater transmembrane transporter activity

AQP7B AQP7P3 AQP7 SLC5A1

3.95e-06201104GO:0005372
GeneOntologyMolecularFunctionglycerol channel activity

AQP7B AQP7P3 AQP7

5.60e-0671103GO:0015254
GeneOntologyMolecularFunctionurea transmembrane transporter activity

AQP7B AQP7P3 AQP7

1.33e-0591103GO:0015204
GeneOntologyMolecularFunctionglycerol transmembrane transporter activity

AQP7B AQP7P3 AQP7

1.33e-0591103GO:0015168
GeneOntologyMolecularFunctionbone sialoprotein binding

ANXA2 ANXA2P2

3.01e-0521102GO:0044730
GeneOntologyMolecularFunctiontransporter activity

GABRR1 GABRR2 SLC7A13 ANO1 AQP7B APOB AQP7P3 ATP9A AQP7 TMEM38B RYR3 SLC5A1 GRAMD1B KCNK10 KCNK2 SLC25A38 ATP11C ATP11A ATP5PD

7.42e-05128911019GO:0005215
GeneOntologyMolecularFunctioncarbohydrate transmembrane transporter activity

AQP7B AQP7P3 AQP7 SLC5A1

8.30e-05421104GO:0015144
GeneOntologyMolecularFunctionwater channel activity

AQP7B AQP7P3 AQP7

1.05e-04171103GO:0015250
GeneOntologyMolecularFunctionchannel activity

GABRR1 GABRR2 ANO1 AQP7B AQP7P3 AQP7 TMEM38B RYR3 KCNK10 KCNK2 ATP5PD

1.53e-0452511011GO:0015267
GeneOntologyMolecularFunctionpassive transmembrane transporter activity

GABRR1 GABRR2 ANO1 AQP7B AQP7P3 AQP7 TMEM38B RYR3 KCNK10 KCNK2 ATP5PD

1.55e-0452611011GO:0022803
GeneOntologyMolecularFunctionintramembrane lipid transporter activity

ANO1 ATP9A ATP11C ATP11A

1.78e-04511104GO:0140303
GeneOntologyMolecularFunctionphosphatidylserine flippase activity

ATP11C ATP11A

2.97e-0451102GO:0140346
GeneOntologyMolecularFunctionphospholipase A2 inhibitor activity

ANXA2 ANXA2P2

2.97e-0451102GO:0019834
GeneOntologyMolecularFunctionurea channel activity

AQP7P3 AQP7

2.97e-0451102GO:0015265
GeneOntologyMolecularFunctionATPase-coupled intramembrane lipid transporter activity

ATP9A ATP11C ATP11A

4.82e-04281103GO:0140326
GeneOntologyMolecularFunctionorganic hydroxy compound transmembrane transporter activity

AQP7B AQP7P3 AQP7 SLC5A1

6.04e-04701104GO:1901618
GeneOntologyMolecularFunctionaminophospholipid flippase activity

ATP11C ATP11A

6.20e-0471102GO:0015247
GeneOntologyMolecularFunctionphosphatidylethanolamine flippase activity

ATP11C ATP11A

6.20e-0471102GO:0090555
GeneOntologyMolecularFunctionlipid transporter activity

ANO1 APOB ATP9A GRAMD1B ATP11C ATP11A

7.62e-041961106GO:0005319
GeneOntologyMolecularFunctioninorganic molecular entity transmembrane transporter activity

GABRR1 GABRR2 ANO1 AQP7B AQP7P3 AQP7 TMEM38B RYR3 SLC5A1 KCNK10 KCNK2 ATP5PD

9.59e-0475811012GO:0015318
GeneOntologyMolecularFunctionphosphatidylserine floppase activity

ATP11C ATP11A

1.06e-0391102GO:0090556
GeneOntologyMolecularFunctionamide transmembrane transporter activity

AQP7B AQP7P3 AQP7

1.60e-03421103GO:0042887
GeneOntologyMolecularFunctiondipeptidyl-peptidase activity

DPP10 FAP

1.91e-03121102GO:0008239
GeneOntologyMolecularFunctionATP-dependent activity

MYO1D MSH3 ATP9A NLRP10 MOV10L1 ATP11C ATP11A TOR3A FIGNL1 DYNC1H1

2.09e-0361411010GO:0140657
GeneOntologyMolecularFunctioncalcium-dependent protein binding

MYO1D ANXA2 ANXA2P2 SEC31A

2.12e-03981104GO:0048306
GeneOntologyMolecularFunctionphospholipase inhibitor activity

ANXA2 ANXA2P2

2.25e-03131102GO:0004859
GeneOntologyMolecularFunctionmagnesium ion binding

ATP9A MOV10L1 THG1L ATP11C ATP11A FIGNL1

2.47e-032471106GO:0000287
GeneOntologyMolecularFunctionglycerophospholipid flippase activity

ATP11C ATP11A

2.62e-03141102GO:0140333
GeneOntologyMolecularFunctionligand-gated monoatomic anion channel activity

GABRR1 GABRR2 ANO1

2.64e-03501103GO:0099095
GeneOntologyMolecularFunctionS100 protein binding

ANXA2 ANXA2P2

3.01e-03151102GO:0044548
GeneOntologyMolecularFunctionATP hydrolysis activity

ATP9A NLRP10 MOV10L1 ATP11C ATP11A TOR3A FIGNL1 DYNC1H1

3.06e-034411108GO:0016887
GeneOntologyBiologicalProcessglycerol transmembrane transport

AQP7B AQP7P3 AQP7

1.21e-0591103GO:0015793
GeneOntologyBiologicalProcesswater transport

AQP7B AQP7P3 AQP7 SLC5A1

2.45e-05321104GO:0006833
GeneOntologyBiologicalProcesspositive regulation of low-density lipoprotein particle receptor binding

ANXA2 ANXA2P2

2.82e-0521102GO:1905597
GeneOntologyBiologicalProcesspolyol transmembrane transport

AQP7B AQP7P3 AQP7

3.14e-05121103GO:0015791
GeneOntologyBiologicalProcessurea transmembrane transport

AQP7B AQP7P3 AQP7

3.14e-05121103GO:0071918
GeneOntologyBiologicalProcesscentrosome localization

PAFAH1B1 ASPM PKHD1 PLXNA2

3.53e-05351104GO:0051642
GeneOntologyBiologicalProcessmicrotubule organizing center localization

PAFAH1B1 ASPM PKHD1 PLXNA2

3.95e-05361104GO:0061842
GeneOntologyBiologicalProcessurea transport

AQP7B AQP7P3 AQP7

5.15e-05141103GO:0015840
GeneOntologyBiologicalProcessfluid transport

AQP7B AQP7P3 AQP7 SLC5A1

7.33e-05421104GO:0042044
GeneOntologyBiologicalProcessneuroblast division

SOX5 NUMBL ASPM

7.86e-05161103GO:0055057
GeneOntologyBiologicalProcesspositive regulation of receptor-mediated endocytosis involved in cholesterol transport

ANXA2 ANXA2P2

8.43e-0531102GO:1905602
GeneOntologyBiologicalProcessnegative regulation of low-density lipoprotein particle receptor catabolic process

ANXA2 ANXA2P2

8.43e-0531102GO:0032804
GeneOntologyBiologicalProcesspositive regulation of low-density lipoprotein particle clearance

ANXA2 ANXA2P2

1.68e-0441102GO:1905581
GeneOntologyBiologicalProcessnegative regulation of receptor catabolic process

ANXA2 ANXA2P2

1.68e-0441102GO:2000645
GeneOntologyBiologicalProcesspositive regulation of intracellular cholesterol transport

ANXA2 ANXA2P2

1.68e-0441102GO:0032385
GeneOntologyBiologicalProcesspositive regulation of intracellular sterol transport

ANXA2 ANXA2P2

1.68e-0441102GO:0032382
GeneOntologyBiologicalProcessretrograde axonal transport

DST PAFAH1B1 DYNC1H1

2.75e-04241103GO:0008090
GeneOntologyBiologicalProcesspositive regulation of plasma membrane repair

ANXA2 ANXA2P2

2.79e-0451102GO:1905686
GeneOntologyBiologicalProcessregulation of low-density lipoprotein particle receptor binding

ANXA2 ANXA2P2

2.79e-0451102GO:1905595
GeneOntologyBiologicalProcessdermatan sulfate biosynthetic process

CHST14 CHST12

2.79e-0451102GO:0030208
GeneOntologyBiologicalProcesspositive regulation of intracellular lipid transport

ANXA2 ANXA2P2

2.79e-0451102GO:0032379
GeneOntologyBiologicalProcesscarbohydrate transmembrane transport

AQP7B AQP7P3 AQP7 SLC5A1 C3 PRKAG2

2.84e-041681106GO:0034219
GeneOntologyBiologicalProcessmaintenance of centrosome location

PAFAH1B1 ASPM

4.17e-0461102GO:0051661
GeneOntologyBiologicalProcesspositive regulation of low-density lipoprotein receptor activity

ANXA2 ANXA2P2

4.17e-0461102GO:1905599
GeneOntologyBiologicalProcessspindle localization

PAFAH1B1 ASPM PKHD1 DYNC1H1

4.53e-04671104GO:0051653
GeneOntologyBiologicalProcessfibrinolysis

ANXA2 ANXA2P2 FAP

4.87e-04291103GO:0042730
GeneOntologyBiologicalProcesscarbohydrate transport

AQP7B AQP7P3 AQP7 SLC5A1 C3 PRKAG2

4.89e-041861106GO:0008643
GeneOntologyBiologicalProcesscell surface receptor protein tyrosine phosphatase signaling pathway

TRIO PTPRD

5.82e-0471102GO:0007185
GeneOntologyBiologicalProcessaminophospholipid translocation

ATP11C ATP11A

5.82e-0471102GO:0140331
GeneOntologyBiologicalProcessregulation of low-density lipoprotein particle receptor catabolic process

ANXA2 ANXA2P2

5.82e-0471102GO:0032803
GeneOntologyBiologicalProcesslow-density lipoprotein particle receptor catabolic process

ANXA2 ANXA2P2

5.82e-0471102GO:0032802
GeneOntologyBiologicalProcesslow-density lipoprotein receptor particle metabolic process

ANXA2 ANXA2P2

5.82e-0471102GO:0032799
GeneOntologyCellularComponentearly endosome

MYO1D ANXA2 ANXA2P2 VPS8 APOB ATP9A WDFY4 WDFY2 SLC5A1 ASAH1 ATP11C ATP11A

1.16e-0548111312GO:0005769
GeneOntologyCellularComponentlipid droplet

ANXA2 ANXA2P2 APOB AQP7P3 AQP7 ABHD4

4.00e-051161136GO:0005811
GeneOntologyCellularComponentAnxA2-p11 complex

ANXA2 ANXA2P2

8.66e-0531132GO:1990665
GeneOntologyCellularComponentPCSK9-AnxA2 complex

ANXA2 ANXA2P2

8.66e-0531132GO:1990667
GeneOntologyCellularComponentvacuolar lumen

ANXA2 APOB CUBN ASAH1 C3 DYNC1H1

4.17e-041781136GO:0005775
GeneOntologyCellularComponentendosome

MYO1D TRIO ANXA2 ANXA2P2 VPS8 APOB SEC31A CUBN ATP9A WDFY4 WDFY2 SLC5A1 AP4E1 ASAH1 ATP11C ATP11A

5.36e-04116711316GO:0005768
GeneOntologyCellularComponentmyelin sheath adaxonal region

ANXA2 ANXA2P2

5.98e-0471132GO:0035749
GeneOntologyCellularComponenttransporter complex

GABRR1 GABRR2 DPP10 ANO1 RYR3 KCNK10 KCNK2 ATP11C ATP11A ATP5PD

8.06e-0455011310GO:1990351
GeneOntologyCellularComponentside of membrane

SPAM1 HTR2C ANO1 CPM CUBN RYR3 TGFBR2 NLRP10 DST CXCR6 CLPTM1 PKHD1 IL27RA

8.92e-0487511313GO:0098552
GeneOntologyCellularComponentcell cortex

GAD1 MYO1D ANXA2 ANXA2P2 AQP7 DST PAFAH1B1 DYNC1H1

9.26e-043711138GO:0005938
GeneOntologyCellularComponentcell surface

SPAM1 HTR2C ANXA2 ANXA2P2 ANO1 CPM CUBN TGFBR2 FAP CXCR6 CLPTM1 KCNK2 PKHD1 C3 IL27RA

9.45e-04111111315GO:0009986
GeneOntologyCellularComponentbasal part of cell

MYO1D ANXA2 ANXA2P2 AQP7B AQP7P3 AQP7 FAP DST

1.04e-033781138GO:0045178
GeneOntologyCellularComponentmonoatomic ion channel complex

GABRR1 GABRR2 DPP10 ANO1 RYR3 KCNK10 KCNK2 ATP5PD

1.04e-033781138GO:0034702
GeneOntologyCellularComponentbrush border membrane

CUBN AQP7P3 AQP7 SLC5A1

1.07e-03831134GO:0031526
GeneOntologyCellularComponentcluster of actin-based cell projections

MYO1D CUBN AQP7P3 AQP7 SLC5A1 PAFAH1B1

1.35e-032231136GO:0098862
GeneOntologyCellularComponentbrush border

MYO1D CUBN AQP7P3 AQP7 SLC5A1

1.42e-031521135GO:0005903
GeneOntologyCellularComponentpinosome

ANXA2 ANXA2P2

1.54e-03111132GO:0044352
GeneOntologyCellularComponentmacropinosome

ANXA2 ANXA2P2

1.54e-03111132GO:0044354
GeneOntologyCellularComponentsmooth endoplasmic reticulum

MYO1D APOB RYR3

1.97e-03461133GO:0005790
GeneOntologyCellularComponentexternal side of plasma membrane

SPAM1 HTR2C ANO1 CUBN TGFBR2 CXCR6 CLPTM1 PKHD1 IL27RA

2.04e-035191139GO:0009897
GeneOntologyCellularComponentmicrotubule

KNTC1 DCDC1 TMEM214 RMDN2 DST PAFAH1B1 ASPM TTLL1 DYNC1H1

2.44e-035331139GO:0005874
GeneOntologyCellularComponentphospholipid-translocating ATPase complex

ATP11C ATP11A

2.53e-03141132GO:1990531
GeneOntologyCellularComponentcontractile actin filament bundle

ANXA2 ANXA2P2 SIPA1L3 DST

2.72e-031071134GO:0097517
GeneOntologyCellularComponentstress fiber

ANXA2 ANXA2P2 SIPA1L3 DST

2.72e-031071134GO:0001725
GeneOntologyCellularComponentmembrane protein complex

GABRR1 GABRR2 DPP10 ANXA2 ANXA2P2 VPS8 ANO1 SEC31A RYR3 AP4E1 TGFBR2 SCAP KCNK10 KCNK2 SUN3 NNT ATP5PD

2.81e-03149811317GO:0098796
GeneOntologyCellularComponentbasal plasma membrane

MYO1D ANXA2 ANXA2P2 AQP7B AQP7P3 AQP7 DST

3.14e-033541137GO:0009925
GeneOntologyCellularComponentchloride channel complex

GABRR1 GABRR2 ANO1

3.64e-03571133GO:0034707
GeneOntologyCellularComponentSchmidt-Lanterman incisure

ANXA2 ANXA2P2

3.74e-03171132GO:0043220
GeneOntologyCellularComponentactomyosin

ANXA2 ANXA2P2 SIPA1L3 DST

3.76e-031171134GO:0042641
GeneOntologyCellularComponentactin filament bundle

ANXA2 ANXA2P2 SIPA1L3 DST

3.87e-031181134GO:0032432
DomainWD40_repeat_dom

KNTC1 ITFG2 VPS8 SEC31A WDFY4 WDFY2 NWD2 SCAP RACK1 WDR97 PAFAH1B1 WDR12 IFT80

2.14e-0829711013IPR017986
DomainWD40_repeat

VPS8 SEC31A WDFY4 WDFY2 NWD2 SCAP RACK1 WDR97 PAFAH1B1 WDR12 IFT80

6.09e-0727211011IPR001680
Domain-

VPS8 SEC31A WDFY4 WDFY2 NWD2 SCAP RACK1 WDR97 PAFAH1B1 WDR12 IFT80 PLXNA2

6.24e-07333110122.130.10.10
DomainWD40/YVTN_repeat-like_dom

VPS8 SEC31A WDFY4 WDFY2 NWD2 SCAP RACK1 WDR97 PAFAH1B1 WDR12 IFT80 PLXNA2

6.65e-0733511012IPR015943
DomainWD_REPEATS_1

VPS8 SEC31A WDFY4 WDFY2 NWD2 SCAP RACK1 WDR97 PAFAH1B1 WDR12 IFT80

7.55e-0727811011PS00678
DomainWD_REPEATS_2

VPS8 SEC31A WDFY4 WDFY2 NWD2 SCAP RACK1 WDR97 PAFAH1B1 WDR12 IFT80

7.82e-0727911011PS50082
DomainWD_REPEATS_REGION

VPS8 SEC31A WDFY4 WDFY2 NWD2 SCAP RACK1 WDR97 PAFAH1B1 WDR12 IFT80

7.82e-0727911011PS50294
DomainWD40

SEC31A WDFY4 WDFY2 NWD2 SCAP RACK1 WDR97 PAFAH1B1 WDR12 IFT80

4.16e-0626811010SM00320
DomainWD40_repeat_CS

WDFY4 WDFY2 NWD2 SCAP RACK1 WDR97 PAFAH1B1 WDR12

5.71e-061641108IPR019775
DomainWD40

SEC31A WDFY4 WDFY2 SCAP RACK1 WDR97 PAFAH1B1 WDR12 IFT80

2.26e-052591109PF00400
DomainGABAAa_rho_rcpt

GABRR1 GABRR2

3.44e-0521102IPR008057
Domain2pore_dom_K_chnl_TREK

KCNK10 KCNK2

3.44e-0521102IPR003976
DomainP_typ_ATPase_c

ATP9A ATP11C ATP11A

6.90e-05141103IPR032630
DomainP-type_ATPase_N

ATP9A ATP11C ATP11A

6.90e-05141103IPR032631
DomainP-type_ATPase_IV

ATP9A ATP11C ATP11A

6.90e-05141103IPR006539
DomainPhoLip_ATPase_C

ATP9A ATP11C ATP11A

6.90e-05141103PF16212
DomainPhoLip_ATPase_N

ATP9A ATP11C ATP11A

6.90e-05141103PF16209
DomainDAPIN

NLRP9 NLRP14 NLRP10

2.82e-04221103PS50824
DomainPYRIN

NLRP9 NLRP14 NLRP10

2.82e-04221103SM01289
DomainPYRIN

NLRP9 NLRP14 NLRP10

2.82e-04221103PF02758
DomainDAPIN

NLRP9 NLRP14 NLRP10

2.82e-04221103IPR004020
DomainNACHT

NLRP9 NLRP14 NLRP10

3.23e-04231103PS50837
DomainNACHT_NTPase

NLRP9 NLRP14 NLRP10

3.23e-04231103IPR007111
Domain-

DPP10 FAP

5.08e-04611022.140.10.30
DomainDPPIV_N

DPP10 FAP

5.08e-0461102PF00930
DomainPeptidase_S9B_N

DPP10 FAP

5.08e-0461102IPR002469
DomainCarb_sulfotransferase-rel

CHST14 CHST12

7.08e-0471102IPR018011
Domain-

ATP9A ATP11C ATP11A

8.71e-043211033.40.1110.10
Domain-

ATP9A ATP11C ATP11A

8.71e-043211032.70.150.10
DomainATPase_P-typ_cyto_domN

ATP9A ATP11C ATP11A

1.13e-03351103IPR023299
DomainATPase_P-typ_P_site

ATP9A ATP11C ATP11A

1.23e-03361103IPR018303
DomainP_typ_ATPase

ATP9A ATP11C ATP11A

1.23e-03361103IPR001757
DomainATPASE_E1_E2

ATP9A ATP11C ATP11A

1.23e-03361103PS00154
DomainATPase_P-typ_transduc_dom_A

ATP9A ATP11C ATP11A

1.33e-03371103IPR008250
DomainE1-E2_ATPase

ATP9A ATP11C ATP11A

1.33e-03371103PF00122
DomainG-protein_beta_WD-40_rep

WDFY2 RACK1 PAFAH1B1 WDR12

1.60e-03851104IPR020472
DomainPeptidase_S9

DPP10 FAP

1.83e-03111102PF00326
DomainPeptidase_S9

DPP10 FAP

1.83e-03111102IPR001375
DomainDHS-like_NAD/FAD-binding_dom

DHPS NNT

2.18e-03121102IPR029035
DomainSulfotransfer_2

CHST14 CHST12

2.18e-03121102PF03567
DomainSulfotransferase

CHST14 CHST12

2.18e-03121102IPR005331
Domain2pore_dom_K_chnl

KCNK10 KCNK2

3.43e-03151102IPR003280
DomainHMG_box

SOX1 SOX5 KMT2D

3.76e-03531103PF00505
DomainHMG

SOX1 SOX5 KMT2D

3.96e-03541103SM00398
Domain-

SOX1 SOX5 KMT2D

4.17e-035511031.10.30.10
DomainP-loop_NTPase

MYO1D MSH3 NLRP9 NLRP14 NLRP10 NWD2 MTIF2 MOV10L1 ASPM TOR3A FIGNL1 DYNC1H1

4.22e-0384811012IPR027417
Pubmed

Molecular genetics of successful smoking cessation: convergent genome-wide association study results.

SOX5 TRIO ATP9A WDFY4 PTPRD KCNK2 NRG3

4.78e-08101115718519826
Pubmed

Maternal genes and facial clefts in offspring: a comprehensive search for genetic associations in two population-based cleft studies from Scandinavia.

SOX1 SOX5 GAD1 SPAM1 APOB TGFBR2 PAFAH1B1 CLPTM1 TBX1

1.67e-06331115920634891
Pubmed

Protein RS1 (RSC1A1) Downregulates the Exocytotic Pathway of Glucose Transporter SGLT1 at Low Intracellular Glucose via Inhibition of Ornithine Decarboxylase.

ANXA2 SLC5A1 RACK1

2.92e-069115327555600
Pubmed

KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.

MYO1D TRIO NUMBL ANXA2 ANXA2P2 SIPA1L3 KIAA1549 PFKP ATP9A GRAMD1B NWD2 DST RACK1 PAFAH1B1 PRKAG2 ATP5PD DYNC1H1

4.86e-0614311151737142655
Pubmed

ATP9B, a P4-ATPase (a putative aminophospholipid translocase), localizes to the trans-Golgi network in a CDC50 protein-independent manner.

ATP9A ATP11C ATP11A

7.58e-0612115321914794
Pubmed

NODs: intracellular proteins involved in inflammation and apoptosis.

NLRP9 NLRP14 NLRP10

7.58e-0612115312766759
Pubmed

Transcriptome profiling reveals expression signatures of cranial neural crest cells arising from different axial levels.

ANXA2 ANXA2P2 PLXNA2

7.58e-0612115328407732
Pubmed

Differential expression of putative transbilayer amphipath transporters.

ATP9A ATP11C ATP11A

9.83e-0613115311015572
Pubmed

AMP-activated protein kinase inhibits TREK channels.

KCNK10 KCNK2

1.08e-052115219840997
Pubmed

Modulation of K2P 2.1 and K2P 10.1 K(+) channel sensitivity to carvedilol by alternative mRNA translation initiation.

KCNK10 KCNK2

1.08e-052115225168769
Pubmed

Mutations of microsatellite instability target genes in sporadic basal cell carcinomas.

MSH3 TGFBR2

1.08e-052115217950544
Pubmed

Vascular endothelial growth factor upregulates expression of annexin A2 in vitro and in a mouse model of ischemic retinopathy.

ANXA2 ANXA2P2

1.08e-052115219536308
Pubmed

Annexin A2 modulates radiation-sensitive transcriptional programming and cell fate.

ANXA2 ANXA2P2

1.08e-052115223148505
Pubmed

Over-expression of AQP7 contributes to improve insulin resistance in adipocytes.

AQP7P3 AQP7

1.08e-052115222877989
Pubmed

ANXA2 (annexin A2) is crucial to ATG7-mediated autophagy, leading to tumor aggressiveness in triple-negative breast cancer cells.

ANXA2 ANXA2P2

1.08e-052115238290972
Pubmed

Gene-based interaction analysis shows GABAergic genes interacting with parenting in adolescent depressive symptoms.

GABRR1 GABRR2

1.08e-052115228660714
Pubmed

The cDNA sequence for the protein-tyrosine kinase substrate p36 (calpactin I heavy chain) reveals a multidomain protein with internal repeats.

ANXA2 ANXA2P2

1.08e-05211523013423
Pubmed

Activation of Annexin A2 signaling at the blood-brain barrier in a mouse model of multiple sclerosis.

ANXA2 ANXA2P2

1.08e-052115235064931
Pubmed

Complex Roles of Annexin A2 in Host Blood-Brain Barrier Invasion by Cryptococcus neoformans.

ANXA2 ANXA2P2

1.08e-052115228130864
Pubmed

Extracellular acidification exerts opposite actions on TREK1 and TREK2 potassium channels via a single conserved histidine residue.

KCNK10 KCNK2

1.08e-052115219667202
Pubmed

GABRR1 and GABRR2, encoding the GABA-A receptor subunits rho1 and rho2, are associated with alcohol dependence.

GABRR1 GABRR2

1.08e-052115219536785
Pubmed

Localization of annexin II in the paranodal regions and Schmidt-Lanterman incisures in the peripheral nervous system.

ANXA2 ANXA2P2

1.08e-052115217549680
Pubmed

Aquaporin 7 is upregulated through the PI3K-Akt pathway and modulates decidualisation of endometrial stromal cells.

AQP7P3 AQP7

1.08e-052115237879294
Pubmed

Annexin A2 promotes proliferative vitreoretinopathy in response to a macrophage inflammatory signal in mice.

ANXA2 ANXA2P2

1.08e-052115239384746
Pubmed

Prolonged Starvation Causes Up-Regulation of AQP1 in Adipose Tissue Capillaries of AQP7 Knock-Out Mice.

AQP7P3 AQP7

1.08e-052115227455244
Pubmed

Involvement of aquaporin-7 in the cutaneous primary immune response through modulation of antigen uptake and migration in dendritic cells.

AQP7P3 AQP7

1.08e-052115221968069
Pubmed

Annexin A2 mediates up-regulation of NF-κB, β-catenin, and stem cell in response to progastrin in mice and HEK-293 cells.

ANXA2 ANXA2P2

1.08e-052115220826156
Pubmed

Prohibitin/annexin 2 interaction regulates fatty acid transport in adipose tissue.

ANXA2 ANXA2P2

1.08e-052115227468426
Pubmed

Microtubule-binding-induced allostery triggers LIS1 dissociation from dynein prior to cargo transport.

PAFAH1B1 DYNC1H1

1.08e-052115237322240
Pubmed

Homocysteine inhibits neoangiogenesis in mice through blockade of annexin A2-dependent fibrinolysis.

ANXA2 ANXA2P2

1.08e-052115219841537
Pubmed

Aquaporin-7 Facilitates Proliferation and Adipogenic Differentiation of Mouse Bone Marrow Mesenchymal Stem Cells by Regulating Hydrogen Peroxide Transport.

AQP7P3 AQP7

1.08e-052115237432580
Pubmed

Annexin A2 Modulates ROS and Impacts Inflammatory Response via IL-17 Signaling in Polymicrobial Sepsis Mice.

ANXA2 ANXA2P2

1.08e-052115227389701
Pubmed

Aquaporin 7 is a beta-cell protein and regulator of intraislet glycerol content and glycerol kinase activity, beta-cell mass, and insulin production and secretion.

AQP7P3 AQP7

1.08e-052115217576812
Pubmed

Annexin II expressed by osteoblasts and endothelial cells regulates stem cell adhesion, homing, and engraftment following transplantation.

ANXA2 ANXA2P2

1.08e-052115217360942
Pubmed

Annexin A2 regulates phagocytosis of photoreceptor outer segments in the mouse retina.

ANXA2 ANXA2P2

1.08e-052115219587120
Pubmed

Annexin A2 at the interface between F-actin and membranes enriched in phosphatidylinositol 4,5,-bisphosphate.

ANXA2 ANXA2P2

1.08e-052115219022301
Pubmed

Multi-Omics Profiling Identifies Microglial Annexin A2 as a Key Mediator of NF-κB Pro-inflammatory Signaling in Ischemic Reperfusion Injury.

ANXA2 ANXA2P2

1.08e-052115238253182
Pubmed

Migraine-Associated TRESK Mutations Increase Neuronal Excitability through Alternative Translation Initiation and Inhibition of TREK.

KCNK10 KCNK2

1.08e-052115230573346
Pubmed

Aquaporin 7 expression in postimplantation mouse uteri: a potential role for glycerol transport in uterine decidualization.

AQP7P3 AQP7

1.08e-052115221130427
Pubmed

The heart requires glycerol as an energy substrate through aquaporin 7, a glycerol facilitator.

AQP7P3 AQP7

1.08e-052115219297367
Pubmed

Dynamic subcellular localization of aquaporin-7 in white adipocytes.

AQP7P3 AQP7

1.08e-052115225643985
Pubmed

Molecular characterization of human Aquaporin-7 gene and its chromosomal mapping.

AQP7P3 AQP7

1.08e-05211529714739
Pubmed

Annexin A2 is a novel cellular redox regulatory protein involved in tumorigenesis.

ANXA2 ANXA2P2

1.08e-052115222185818
Pubmed

Cryoprotectants up-regulate expression of mouse oocyte AQP7, which facilitates water diffusion during cryopreservation.

AQP7P3 AQP7

1.08e-052115223290745
Pubmed

A competitive hexapeptide inhibitor of annexin A2 prevents hypoxia-induced angiogenic events.

ANXA2 ANXA2P2

1.08e-052115221486955
Pubmed

Structures of human dynein in complex with the lissencephaly 1 protein, LIS1.

PAFAH1B1 DYNC1H1

1.08e-052115236692009
Pubmed

The N-terminal domain of human GABA receptor rho1 subunits contains signals for homooligomeric and heterooligomeric interaction.

GABRR1 GABRR2

1.08e-05211529153229
Pubmed

Lipid raft endocytosis and exosomal transport facilitate extracellular trafficking of annexin A2.

ANXA2 ANXA2P2

1.08e-052115221737841
Pubmed

Expression and effects of modulation of the K2P potassium channels TREK-1 (KCNK2) and TREK-2 (KCNK10) in the normal human ovary and epithelial ovarian cancer.

KCNK10 KCNK2

1.08e-052115223479219
Pubmed

LIS1 promotes the formation of activated cytoplasmic dynein-1 complexes.

PAFAH1B1 DYNC1H1

1.08e-052115232341549
Pubmed

Regulation of the low-dose radiation paracrine-specific anchorage-independent growth response by annexin A2.

ANXA2 ANXA2P2

1.08e-052115219580511
Pubmed

Transactivation of SOX5 by Brachyury promotes breast cancer bone metastasis.

SOX5 TBX1

1.08e-052115231713604
Pubmed

Aquaporin-7 Regulates the Response to Cellular Stress in Breast Cancer.

AQP7P3 AQP7

1.08e-052115232631905
Pubmed

Elimination of the rho1 subunit abolishes GABA(C) receptor expression and alters visual processing in the mouse retina.

GABRR1 GABRR2

1.08e-052115212019334
Pubmed

Genomic structure and insulin-mediated repression of the aquaporin adipose (AQPap), adipose-specific glycerol channel.

AQP7P3 AQP7

1.08e-052115211457862
Pubmed

Selenomethionine promotes ANXA2 phosphorylation for proliferation and protein synthesis of myoblasts and skeletal muscle growth.

ANXA2 ANXA2P2

1.08e-052115236739096
Pubmed

Cardioprotective effect of St. Thomas' Hospital No. 2 solution against age-related changes in aquaporin-7-deficient mice.

AQP7P3 AQP7

1.08e-052115237691043
Pubmed

Methionine-induced hyperhomocysteinemia reverts fibrinolytic pathway activation in a murine model of acute promyelocytic leukemia.

ANXA2 ANXA2P2

1.08e-052115222517898
Pubmed

Aquaporin7 expression during perinatal development of mouse brain.

AQP7P3 AQP7

1.08e-052115217052846
Pubmed

Anxa2 gene silencing attenuates obesity-induced insulin resistance by suppressing the NF-κB signaling pathway.

ANXA2 ANXA2P2

1.08e-052115230462534
Pubmed

The glycine hinge of transmembrane segment 2 modulates the subcellular localization and gating properties in TREK channels.

KCNK10 KCNK2

1.08e-052115228676394
Pubmed

Inhibition of the membrane repair protein annexin-A2 prevents tumor invasion and metastasis.

ANXA2 ANXA2P2

1.08e-052115238092984
Pubmed

Tyrosine 23 phosphorylation-dependent cell-surface localization of annexin A2 is required for invasion and metastases of pancreatic cancer.

ANXA2 ANXA2P2

1.08e-052115221572519
Pubmed

Hypoxia-inducible factor-1 drives annexin A2 system-mediated perivascular fibrin clearance in oxygen-induced retinopathy in mice.

ANXA2 ANXA2P2

1.08e-052115221788340
Pubmed

The Membrane Phospholipid Binding Protein Annexin A2 Promotes Phagocytosis and Nonlytic Exocytosis of Cryptococcus neoformans and Impacts Survival in Fungal Infection.

ANXA2 ANXA2P2

1.08e-052115227371724
Pubmed

Morphologic and functional analysis of sperm and testes in Aquaporin 7 knockout mice.

AQP7P3 AQP7

1.08e-052115217123523
Pubmed

Arsenite transport by mammalian aquaglyceroporins AQP7 and AQP9.

AQP7P3 AQP7

1.08e-052115211972053
Pubmed

Developmental regulation and activity-dependent maintenance of GABAergic presynaptic inhibition onto rod bipolar cell axonal terminals.

GABRR1 GAD1

1.08e-052115223583111
Pubmed

Formation of Functional Heterodimers by TREK-1 and TREK-2 Two-pore Domain Potassium Channel Subunits.

KCNK10 KCNK2

1.08e-052115227129242
Pubmed

Adaptation to fasting by glycerol transport through aquaporin 7 in adipose tissue.

AQP7P3 AQP7

1.08e-052115215591341
Pubmed

Annexin A2 Deficiency Exacerbates Neuroinflammation and Long-Term Neurological Deficits after Traumatic Brain Injury in Mice.

ANXA2 ANXA2P2

1.08e-052115231817350
Pubmed

ANNEXIN A2 FACILITATES NEOVASCULARIZATION TO PROTECT AGAINST MYOCARDIAL INFARCTION INJURY VIA INTERACTING WITH MACROPHAGE YAP AND ENDOTHELIAL INTEGRIN Î’3.

ANXA2 ANXA2P2

1.08e-052115237832154
Pubmed

Cell-surface translocation of annexin A2 contributes to bleomycin-induced pulmonary fibrosis by mediating inflammatory response in mice.

ANXA2 ANXA2P2

1.08e-052115230902828
Pubmed

Progressive adipocyte hypertrophy in aquaporin-7-deficient mice: adipocyte glycerol permeability as a novel regulator of fat accumulation.

AQP7P3 AQP7

1.08e-052115215746100
Pubmed

Cell surface translocation of annexin A2 facilitates glutamate-induced extracellular proteolysis.

ANXA2 ANXA2P2

1.08e-052115224742684
Pubmed

Annexin A2 depletion exacerbates the intracerebral microhemorrhage induced by acute rickettsia and Ebola virus infections.

ANXA2 ANXA2P2

1.08e-052115232687500
Pubmed

Aquaporin7 plays a crucial role in tolerance to hyperosmotic stress and in the survival of oocytes during cryopreservation.

AQP7P3 AQP7

1.08e-052115226634435
Pubmed

Annexin A2 binds to endosomes following organelle destabilization by particulate wear debris.

ANXA2 ANXA2P2

1.08e-052115222453828
Pubmed

Agents that bind annexin A2 suppress ocular neovascularization.

ANXA2 ANXA2P2

1.08e-052115220607799
Pubmed

A new role for host annexin A2 in establishing bacterial adhesion to vascular endothelial cells: lines of evidence from atomic force microscopy and an in vivo study.

ANXA2 ANXA2P2

1.08e-052115231253864
Pubmed

AQP7 is localized in capillaries of adipose tissue, cardiac and striated muscle: implications in glycerol metabolism.

AQP7P3 AQP7

1.08e-052115217077387
Pubmed

X-linked hypoparathyroidism region on Xq27 is evolutionarily conserved with regions on 3q26 and 13q34 and contains a novel P-type ATPase.

ATP11C ATP11A

1.08e-052115215533723
Pubmed

A new role for aquaporin 7 in insulin secretion.

AQP7P3 AQP7

1.08e-052115222415076
Pubmed

Annexin A2 is involved in antiphospholipid antibody-mediated pathogenic effects in vitro and in vivo.

ANXA2 ANXA2P2

1.08e-052115219628708
Pubmed

Two types of type IV P-type ATPases independently re-establish the asymmetrical distribution of phosphatidylserine in plasma membranes.

ATP11C ATP11A

1.08e-052115236162506
Pubmed

Annexin A2 binds to the localization signal in the 3' untranslated region of c-myc mRNA.

ANXA2 ANXA2P2

1.08e-052115215654879
Pubmed

Anti-dsDNA antibodies bind to mesangial annexin II in lupus nephritis.

ANXA2 ANXA2P2

1.08e-052115220847146
Pubmed

The genetics of NOD-like receptors in Crohn's disease.

NLRP9 NLRP14 NLRP10

1.25e-0514115320403135
Pubmed

TREX tetramer disruption alters RNA processing necessary for corticogenesis in THOC6 Intellectual Disability Syndrome.

SOX1 ANXA2 ANXA2P2

1.25e-0514115338388531
Pubmed

NALPs: a novel protein family involved in inflammation.

NLRP9 NLRP14 NLRP10

1.25e-0514115312563287
Pubmed

Quantitative trait loci for body size components in mice.

SOX5 FBXO24 SCAP NRG3 TBX1

1.92e-0598115516783635
Pubmed

Systematically defining selective autophagy receptor-specific cargo using autophagosome content profiling.

TRIO ANXA2 APOB SEC31A PFKP DST RACK1 PAFAH1B1 CLPTM1 C3 WDR12 ATP11A TOR3A ATP5PD DYNC1H1

2.52e-0512971151533545068
Pubmed

STARD3NL inhibits the osteogenic differentiation by inactivating the Wnt/β-catenin pathway via binding to Annexin A2 in osteoporosis.

ANXA2 ANXA2P2

3.24e-053115235098646
Pubmed

Coordinated regulation of fat-specific and liver-specific glycerol channels, aquaporin adipose and aquaporin 9.

AQP7P3 AQP7

3.24e-053115212351427
Pubmed

Anti-obesity effect of carboxymethyl chitin by AMPK and aquaporin-7 pathways in 3T3-L1 adipocytes.

AQP7P3 AQP7

3.24e-053115220573496
Pubmed

The Annexin A2-Notch regulatory loop in hepatocytes promotes liver fibrosis in NAFLD by increasing osteopontin expression.

ANXA2 ANXA2P2

3.24e-053115235413401
Pubmed

Annexin A2 supports pulmonary microvascular integrity by linking vascular endothelial cadherin and protein tyrosine phosphatases.

ANXA2 ANXA2P2

3.24e-053115228694388
Pubmed

High Podocalyxin levels promote cell viability partially through up-regulation of Annexin A2.

ANXA2 ANXA2P2

3.24e-053115227470587
Pubmed

Consensus phosphorylation sites of human GABA(c)/GABArho receptors are not critical for inhibition by protein kinase C activation.

GABRR1 GABRR2

3.24e-05311529839716
Pubmed

Annexins--unique membrane binding proteins with diverse functions.

ANXA2 ANXA2P2

3.24e-053115215169834
GeneFamilyWD repeat domain containing

SEC31A WDFY4 WDFY2 SCAP RACK1 WDR97 PAFAH1B1 WDR12 IFT80

1.34e-06262759362
GeneFamilyATPase phospholipid transporting

ATP9A ATP11C ATP11A

3.01e-05157531210
GeneFamilyNLR family

NLRP9 NLRP14 NLRP10

1.48e-0425753666
GeneFamilyPyrin domain containing|Pyrin and HIN domain family

NLRP9 NLRP14 NLRP10

1.48e-0425753994
GeneFamilyCD molecules|DASH family

DPP10 FAP

3.52e-0477521205
GeneFamilyPotassium two pore domain channel subfamily K

KCNK10 KCNK2

1.72e-0315752277
GeneFamilySRY-boxes

SOX1 SOX5

2.77e-0319752757
GeneFamilyGamma-aminobutyric acid type A receptor subunits

GABRR1 GABRR2

2.77e-0319752563
GeneFamilyAtaxins|Trinucleotide repeat containing

NUMBL KMT2D

4.79e-0325752775
CoexpressionGAVIN_FOXP3_TARGETS_CLUSTER_P6

TMEM38B ABHD4 TGFBR2 MTMR7 ASPM FIGNL1

3.32e-06931146M1735
CoexpressionGAVIN_FOXP3_TARGETS_CLUSTER_P6

TMEM38B ABHD4 TGFBR2 MTMR7 ASPM FIGNL1

3.76e-06951146MM1217
CoexpressionGSE11386_NAIVE_VS_MEMORY_BCELL_UP

KNTC1 RMDN2 CXCR6 CLPTM1 ASPM CRYBG1 FIGNL1

1.70e-051851147M374
CoexpressionGSE17721_0.5H_VS_4H_GARDIQUIMOD_BMDC_UP

APOB ABHD4 TMEM129 MTIF2 UTP20 TTLL1 PRKAG2

2.80e-052001147M4139
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_3|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SLC7A13 KIAA1549 AQP7B CUBN AQP7 SLC5A1 GRAMD1B KCNK10 PKHD1

9.04e-1017711592f81b26be89cc2fd8eafadaf7eae3c6ad6521462
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_3|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SLC7A13 KIAA1549 AQP7B CUBN AQP7 SLC5A1 GRAMD1B PTPRD KCNK10

1.40e-091861159a417e1e21313a7e05951038cdef5ac672a9f727c
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_3|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SLC7A13 AQP7B CUBN SLC5A1 GRAMD1B PTPRD KCNK10 NRG3

2.51e-0818211584a9c13932e7163fd37a3dcc4c6ca3bbea5372459
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_3|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

SLC7A13 KIAA1549 AQP7B CUBN AQP7 SLC5A1 GRAMD1B KCNK10

2.62e-08183115885446581999cd66b171c4f69b7eb8b0bbbaa8617
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_3|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SLC7A13 KIAA1549 AQP7B CUBN AQP7 SLC5A1 GRAMD1B KCNK10

2.74e-0818411589434731f651820b05335085582960f08fbf895de
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_3|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

SLC7A13 SIPA1L3 AQP7B CUBN SLC5A1 GRAMD1B PKHD1 ATP11A

2.98e-081861158b1edc341d6684b347dc9e21b34f62f51d095d735
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

MYO1D TRIO CPM PFKP DST PKHD1 ATP11A NRG3

4.29e-081951158938b31dbf1674ee6fd0123bc88391ddcaf151217
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Thick_Ascending_Limb_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

MYO1D TRIO CPM PFKP DST PKHD1 ATP11A NRG3

4.29e-081951158d39e9e6544f49e677ebe528c6fe60b99a3630e30
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_3|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

SLC7A13 AQP7B CUBN SLC5A1 GRAMD1B PTPRD KCNK10

3.82e-0717611571595dbeee336a81e581325d63208ec6262664ee9
ToppCellwk_15-18-Epithelial-Distal_epithelial_progenitor-epi-tip_intermediate|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

POLE KIAA1549 KMT2D WDR97 PKHD1 ATP11A PLXNA2

5.34e-071851157636505a3d96f75d951ab42bcf8af6ae07abc732d
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SOX5 MXRA5 KIAA1549 SERINC2 AQP7 CRYBG1 PRKAG2

7.35e-0719411574579b4a44f7c731553a284843c296866027d7c0e
ToppCellSubstantia_nigra-Macroglia-POLYDENDROCYTE-P3-Tnr-Polydendrocyte.Tnr.Cspg5-Dad1_(Cspg5)-|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

SERINC2 FNDC1 ASPRV1 FIGNL1 IL27RA

1.82e-0678115583d308b15cb3c0820a27b95c8bc85afadf98370e
ToppCellSubstantia_nigra-Macroglia-POLYDENDROCYTE-P3-Tnr-Polydendrocyte.Tnr.Cspg5-Dad1_(Cspg5)|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

SERINC2 FNDC1 ASPRV1 FIGNL1 IL27RA

1.82e-06781155387e7e07a5a509dc8415a7cb83a2c3940ca1ec85
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Degenerative_Descending_Thin_Limb_Cell_Type_3|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

DCDC1 CPM RYR3 PKHD1 C3 NRG3

4.34e-0616411561cb5fbd7050650047ad6f2ca792118e98d58d22b
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

TRIO CPM PKHD1 C3 ATP11A NRG3

5.70e-0617211560c2d0bb767e5ce089b42ad49e8b303a103de2d5c
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Thick_Ascending_Limb_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

TRIO CPM PKHD1 C3 ATP11A NRG3

5.70e-061721156eeed177a03c116e9815a8e086d24efc9643b16a4
ToppCelllung|World / shred on tissue and cell subclass

ANXA2 CPM TGFBR2 RACK1 ASAH1 C3

6.94e-0617811567b1e371272328d6b6c3994382d64281ffc737db2
ToppCellPND03-Epithelial-Epithelial_Airway-Neurosecretory|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

GAD1 SLC5A1 NWD2 KCNK2 ATP11A TBX1

7.63e-061811156092a971661b0aa06c1cdf428dbfa7339a26fb678
ToppCellPND10-Immune-Immune_Myeloid-Dendritic-cDC1|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

TRIO POLE WDFY4 NLRP10 ASPM FIGNL1

8.13e-061831156ab38264daddccdf5ffb75ff2210b27423eca6bc0
ToppCellPND10-Immune-Immune_Myeloid-Dendritic|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

TRIO POLE WDFY4 NLRP10 ASPM FIGNL1

8.13e-061831156e4911601dca2c0ecb448cdb6b222dedfc0c8bf6c
ToppCellPND10-Immune-Immune_Myeloid-Dendritic-cDC1-cDC1_G2M|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

TRIO POLE WDFY4 NLRP10 ASPM FIGNL1

8.13e-061831156263bfa1d8a7314bc3156c735c403c3bab8ea4dac
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Thick_Ascending_Limb_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

MYO1D ANXA2 CPM PFKP DST PKHD1

9.19e-06187115687b3d0478693d4c54ff06b74e5903036b9c1ee6a
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SLC7A13 CUBN SLC5A1 GRAMD1B PTPRD KCNK10

9.19e-0618711561b82920588f9e26ef1db244d452736d75fcfd342
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Intermediate_tubule_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

MYO1D ANXA2 CPM PFKP DST PKHD1

9.19e-06187115642a1267bfc27b4460b8409ada580a87c4385841c
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

MYO1D ANXA2 CPM PFKP DST PKHD1

9.19e-06187115664afdea159f5e67a1e5cea35ce898aae6e80aea5
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

KIAA1549 CPM CUBN GRAMD1B PTPRD PKHD1

9.19e-061871156dcf6475ece5b34d9d58a0d1f51c18acedb19c119
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SOX5 MYO1D ANO1 KIAA1549 CPM ATP11C

9.19e-06187115615d6e158562d7d85af3ceaf955439b379c8fce81
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

KIAA1549 CPM CUBN GRAMD1B PTPRD PKHD1

9.19e-061871156f1356273bd3587b6883295edf15cb9cdb706c057
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-glomerular_mesenchymal_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SOX5 MYO1D ANO1 KIAA1549 CPM ATP11C

9.19e-061871156f62074b631fd45ad299c69d71b09267b04d656ee
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SLC7A13 CUBN SLC5A1 GRAMD1B PTPRD KCNK10

9.19e-061871156c1e4c0345f9bfa0538730bad5ff3fa5240168b25
ToppCellFetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_1-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

MYO1D ANXA2 CPM PFKP ATP11A PLXNA2

9.48e-06188115643a3a59f92ad93509d4166bd025aed0b1b39a008
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SOX5 AKT3 MXRA5 CWH43 CRYBG1 PRKAG2

9.77e-0618911563a295c215b5c18e7c673f92b7af5be523421682c
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

DCDC1 TRIO PTPRD PKHD1 ATP11A NRG3

9.77e-0618911563b48b0d220cc24d5170713d61fa91f5bb6c21841
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

DCDC1 CUBN PTPRD PKHD1 ATP11A NRG3

9.77e-06189115628b502611829e4a24caff2562545c7db97686099
ToppCelldroplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_ductal_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ANXA2 ANO1 SERINC2 SLC5A1 PKHD1 C3

1.07e-051921156f3133bbbf938a39062a9b1d1181003bb48174695
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Degenerative_Outer_Medullary_Collecting_Duct_Principal_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SOX5 MXRA5 CWH43 ASAH1 CRYBG1 PRKAG2

1.07e-0519211560bb06738e1c3ec0c044a7ee61f6cf1d4781fb53c
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Degenerative_Outer_Medullary_Collecting_Duct_Principal_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SOX5 MXRA5 CWH43 ASAH1 CRYBG1 PRKAG2

1.10e-051931156e7012f7b53971972299db34fa51ff51a4e4987fe
ToppCellCOVID-19-kidney-CD-PC|kidney / Disease (COVID-19 only), tissue and cell type

SOX5 MXRA5 PFKP PKHD1 CRYBG1 PRKAG2

1.10e-051931156738689d009e4b118d7ce3171a207294b95cbe78b
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Degenerative_Outer_Medullary_Collecting_Duct_Principal_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

SOX5 MXRA5 CWH43 ASAH1 CRYBG1 PRKAG2

1.13e-051941156be869e186386d03ebb670971dd24fa656b4b0edf
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Intermediate_tubule_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

DCDC1 MYO1D CPM PFKP PKHD1 ATP11A

1.13e-051941156e577d9e88390b36b5a09b97fe1026089892275a3
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

SOX5 MXRA5 CWH43 ASAH1 CRYBG1 PRKAG2

1.13e-0519411564d6c9b016e3a0641954a8ea10c97d1cd76fadd9f
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

MXRA5 KIAA1549 SERINC2 AQP7 CRYBG1 PRKAG2

1.17e-0519511563d6d3de8ada6dce3dc789c15b50cc066e7100496
ToppCellFibroblasts-DKK3+_Fibroblasts|Fibroblasts / Immune cells in Rheumatoid Arthritis Joint Synovial Tissues

MXRA5 MYO1D TRIO FNDC1 PTPRD PLXNA2

1.20e-05196115624d64b67aa9b0e8215ad06f9101c1314b3483620
ToppCellParenchymal-NucSeq|Parenchymal / Cell types per location group and 10X technology with lineage, and cell group designations

SOX5 MYO1D TRIO SIPA1L3 PTPRD ATP11A

1.27e-0519811561996373bdccc55aac347d349bd22f6aad6d0c668
ToppCellLPS_IL1RA_TNF-Epithelial_alveolar-AT_1|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

MYO1D ANXA2 PKHD1 C3 ATP11A IFT80

1.31e-0519911561c70e7d6bd25980e1b92aa1cac3f3c95d9651b4b
ToppCellCOVID-19-kidney-Epithelial_(EC)|COVID-19 / Disease (COVID-19 only), tissue and cell type

DPP10 SLC7A13 RYR3 PKHD1 NRG3

2.48e-051331155a8abb6b54862123961ae6defbf251ee6e9575258
ToppCellPND28-Epithelial-Epithelial_Airway-Neurosecretory-Secretory-Secretory_mature|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SLC5A1 NWD2 KCNK2 PKHD1 ATP11A

3.74e-0514511559b69bfdbf91ef197b4c483617aa67498d9d2cd79
ToppCellPND28-Epithelial-Epithelial_Airway-Neurosecretory-Secretory|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SLC5A1 NWD2 KCNK2 PKHD1 ATP11A

3.74e-05145115531af9fce1dcd7e8ae1604476598e099232017ee9
ToppCellfacs-Lung-Endomucin-24m-Endothelial-Capillary_Type_1_Cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DPP10 POLE NWD2 MOV10L1 PKHD1

3.74e-05145115596712c68ab759d7ade0d912581a1a7c25dc6def8
ToppCellPND28-Epithelial-Epithelial_Airway-Neurosecretory|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SLC5A1 NWD2 KCNK2 PKHD1 ATP11A

3.74e-05145115576f0cde9acdc3ad5948c007dccf312665972c9e6
ToppCelllung-Type_II_Pneumocytes|lung / shred on tissue and cell subclass

CPM RACK1 C3 ATP11A PLXNA2

4.00e-0514711558a3039de45b8087f8319e2e37329acf7278219b7
ToppCellfacs-Skin-nan-24m-Epithelial-inner_bulge|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ANXA2 KCNK2 PKHD1 PLXNA2 TBX1

5.15e-051551155fa2776d258e0420b2895de1008e292ad7725dac0
ToppCellFetal_29-31_weeks-Immune-dendritic_cell-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

SIPA1L3 WDFY4 TMEM38B GRAMD1B KCNK10

5.15e-0515511559f937ae48767fdcf1a944af4de0530d9c0ab441d
ToppCellPND03-Epithelial-Epithelial_Airway-Neurosecretory-Secretory-Secretory_mature|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SLC5A1 NWD2 KCNK2 ATP11A TBX1

6.16e-051611155c4970501c038ed36de447da70eabff020ad78713
ToppCellPND03-Epithelial-Epithelial_Airway-Neurosecretory-Secretory|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SLC5A1 NWD2 KCNK2 ATP11A TBX1

6.16e-05161115541a89a3d99a9bd6039a3d881d1d9dcd18bc07f25
ToppCellfacs-Pancreas-Endocrine-3m-Epithelial-pancreatic_ductal_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ANXA2 SERINC2 SLC5A1 PKHD1 HSD17B2

6.34e-0516211553a1cbfed5a063131d49e3c1584f62b12660ecb36
ToppCellfacs-Pancreas-Endocrine-3m-Epithelial-pancreatic_ductal_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ANXA2 SERINC2 SLC5A1 PKHD1 HSD17B2

6.34e-05162115504b3c38bb27fa369a9ac5b60883f8b058abc5180
ToppCellfacs-Marrow-B-cells-24m-Lymphocytic-CD4-positive,_alpha-beta_T_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SOX5 CHST14 ATP9A CXCR6 PLXNA2

7.33e-051671155713899690e4acd9d259645e363c26983d6ef3022
ToppCellfacs-Marrow-B-cells-24m-Lymphocytic-BM_CD4_T_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SOX5 CHST14 ATP9A CXCR6 PLXNA2

7.33e-051671155d30b96c39da3dd02500443877a4eb3500e26802c
ToppCellnucseq-Epithelial-Epithelial_Neuro-Secretory-PNEC|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

SOX1 DPP10 MTMR7 KCNK10 FIGNL1

8.19e-051711155f4321133190a3df9d31f5d4021a464d3840145f1
ToppCellnucseq-Epithelial-Epithelial_Neuro-Secretory-PNEC-PNEC|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

SOX1 DPP10 MTMR7 KCNK10 FIGNL1

8.19e-051711155ed4fb6c84579d99df33de5f8f928c3cd2f3d3d72
ToppCellnucseq-Epithelial-Epithelial_Neuro-Secretory|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

SOX1 DPP10 MTMR7 KCNK10 FIGNL1

8.42e-051721155d0cdedd734406988a9a93d7300c7b1a8b4b45c38
ToppCellE18.5-Epithelial-Epithelial_Airway-Neurosecretory-Secretory-Secretory_prolif|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

KNTC1 MTMR7 NWD2 DHPS TBX1

8.42e-0517211551bbf5ed7d13635f9a7e528060341e0652699bd7c
ToppCelldroplet-Heart-HEART-1m-Endothelial-leukocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

VPS8 SERINC2 RYR3 GRAMD1B TBX1

8.65e-0517311559dc7746a84f0e268a7c061e1bbcd5e31903034dc
ToppCellMesenchymal_cells-Osteo-CAR|Mesenchymal_cells / Lineage and Cell class

WDFY4 FAP PTPRD KCNK2 PLXNA2

8.89e-051741155430e3cd61bc2a471959faa40e817aa4dd7d82d28
ToppCellT_cells-Tph_and_Tfh|T_cells / Immune cells in Rheumatoid Arthritis Joint Synovial Tissues

MAGEH1 CPM ATP9A WDFY2 GRAMD1B

9.38e-05176115556c055488e34605d32562571a2fee621b47c9441
ToppCellRV-11._Adipocyte|World / Chamber and Cluster_Paper

SOX5 CPM ATP9A AQP7 NWD2

9.63e-051771155f0edf04930692418953e4f00a917257804ec0ffd
ToppCellRV-11._Adipocyte|RV / Chamber and Cluster_Paper

SOX5 CPM ATP9A AQP7 NWD2

9.89e-051781155278bbea5cf8f0589f71675c7a3d00679391b5253
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_2-Inh_L1-3_VIP_ZNF322P1|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

GAD1 HTR2C ANXA2 RYR3 FNDC1

9.89e-0517811552a36475c260088f69f3b8c282d910e5eaa5c5c2d
ToppCelldroplet-Heart-4Chambers-21m-Mesenchymal-nan|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KIAA1549 SLC35G2 RMDN2 PTPRD TTLL1

1.02e-041791155b44e2d53b82c3c141bfc6539054b19708200a0d9
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_3|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

SLC7A13 KIAA1549 CUBN SLC5A1 GRAMD1B

1.02e-041791155d1ef7e1cb00336118e387b47f4f8120f53584391
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CUBN TMEM38B SLC5A1 PTPRD NRG3

1.02e-04179115558ae5a97fe2a14e1c6fdeb886397eb06fdaf0428
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Outer_Medullary_Collecting_Duct_Principal_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SOX5 KIAA1549 AQP7 PRKAG2 NRG3

1.02e-041791155d3438fed0d85d5ed5afa8ff820c45143d77b6c0d
ToppCellLV|World / Chamber and Cluster_Paper

VPS8 AQP7 SLC5A1 GRAMD1B ASAH1

1.04e-0418011555ac6f485a58bb29462fec02dfbe8eb70864eafe3
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SOX5 MXRA5 CWH43 CRYBG1 PRKAG2

1.04e-041801155788d5fbf688365b5d92d3aa19b9f8e9448f8be5a
ToppCellPBMC_fresh-frozen-Mild-Moderate_progression_d02_child-Lymphocytic-Lymphocytic_B-Plasma_cell-B_c06-MKI67|Mild-Moderate_progression_d02_child / Compartment, severity and other cell annotations on 10x 3' data (130k)

SRA1 ANXA2 SLC35G2 SCAP ASPM

1.07e-041811155c18e5a3f5d99043fa3cb33e2ac33fa98cd15d3db
ToppCellPND28-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial-Mesothelial_mature|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ANO1 TMEM214 RBM28 PTPRD C3

1.07e-041811155330d4322f4c4373f706273c1f4e218b59051b7fd
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_2-Inh_L1-3_VIP_ZNF322P1|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

GAD1 HTR2C ANO1 RYR3 FNDC1

1.07e-041811155062f00736eed96e4f4327615d093558dd7d82b20
ToppCellFetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

MYO1D CPM C3 ATP11A PLXNA2

1.07e-041811155576da14ab3107f89e1f44a4a439d1bef5bb42370
ToppCellmetastatic_Brain-Fibroblasts-Myofibroblasts|metastatic_Brain / Location, Cell class and cell subclass

MXRA5 FAP FNDC1 PTPRD NRG3

1.07e-041811155bd0b5f74f9c81ec0f1592710774a4fdf33d9d5a9
ToppCellPND28-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ANO1 TMEM214 RBM28 PTPRD C3

1.07e-0418111553f4d5d79c1286614514b0e8134079d6128a2a23e
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Cortical_Collecting_Duct_Principal_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

SOX5 MXRA5 CWH43 CRYBG1 PRKAG2

1.07e-041811155b7c85fbef3c06d5dc32a2a58f8d3dfabf1d79d9f
ToppCellfacs-Lung-18m-Epithelial-airway_epithelial-club_cell|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CWH43 SERINC2 GRAMD1B KCNK2 TBX1

1.07e-0418111554a0f1b121570430afb100c589657d931184e124f
ToppCellfacs-Lung-18m-Epithelial-airway_epithelial-club_cell-club_cell|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CWH43 SERINC2 GRAMD1B KCNK2 TBX1

1.07e-04181115534b49092f71128898af3b311170c4ed8adfefcff
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CUBN SLC5A1 GRAMD1B PTPRD KCNK10

1.10e-041821155e1e58176f533092b6b974ca1ce8b02192a6e193d
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Connecting_Tubule_Principal_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SOX5 MXRA5 CWH43 CRYBG1 PRKAG2

1.10e-041821155f96095b81188b52db8fcfca4837129cfcd9bd7b7
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_2-Inh_L1-3_VIP_ZNF322P1|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

GAD1 HTR2C ANO1 RYR3 FNDC1

1.10e-041821155d3a037268f026eb2f84428b1821022503cef7756
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CUBN SLC5A1 GRAMD1B PTPRD KCNK10

1.10e-04182115557bb5a2da976464ba7c4460106bd9f692008ebd9
ToppCelldroplet-Kidney-KIDNEY-1m-Epithelial-Epcam_____kidney_distal_convoluted_tubule_epithelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CWH43 SERINC2 CPM ME3 NNT

1.13e-041831155f3728b1a51951c7349f77a3e4d2671ca3a8d2a44
ToppCellCOVID-19-kidney-PCT-S1|kidney / Disease (COVID-19 only), tissue and cell type

KIAA1549 CUBN SLC5A1 PTPRD PKHD1

1.16e-04184115551ed1ebfdef45149541917c66cbacad87072e51f
ToppCellnormal_Lung-Fibroblasts-Myofibroblasts|normal_Lung / Location, Cell class and cell subclass

MXRA5 FAP FNDC1 PTPRD MOV10L1

1.16e-0418411550b336489c10e8c3c957795dd845454f03404382b
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5-Inh_L1-6_LAMP5_CA13_(Lamp5_Lhx6_1)|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SOX1 GAD1 ANO1 ASPM ATP11C

1.16e-041841155ae0a77e3e520a246b17776bb19503519636b02ee
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive|renal_medulla_nuclei / Celltypes from Cells and Nuclei per compartment and clinical group

TRIO DST PTPRD C3 NRG3

1.16e-041841155d2bf0135eb56bb410997dccea39c5ede88a0617f
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_2|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SOX1 GAD1 HTR2C ANO1 KCNK2

1.16e-04184115532473dbdb2de66391157c5814ef34e790806e4f2
ToppCell3'-GW_trimst-2-LargeIntestine-Endothelial-lymphatic_endothelial-LEC4_(STAB2+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

GAD1 ANXA2 PFKP TGFBR2 TBX1

1.16e-0418411553b0389c3a5a16697de860e98ebc48ed39ede646f
ToppCellAdult-Epithelial-alveolar_epithelial_cell_type_1-D175|Adult / Lineage, Cell type, age group and donor

MYO1D SIPA1L3 SLC5A1 DST NRG3

1.19e-04185115532b4e68e551d435a732f253f6ad83408c759a642
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_2-Inh_L1-3_VIP_ZNF322P1|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

GAD1 HTR2C ANO1 RYR3 FNDC1

1.19e-0418511550b5a0df58ae2ad8261f40f152775747af4f3937a
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5-Inh_L1-6_LAMP5_CA13_(Lamp5_Lhx6_1)|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SOX1 GAD1 ANO1 ASPM ATP11C

1.22e-04186115577592a6397b44b2b59a4fc39d7224dd95343efe6
ToppCellAdult-Epithelial-club_cell-D231|Adult / Lineage, Cell type, age group and donor

DPP10 HTR2C CUBN PTPRD HSD17B2

1.25e-041871155ee59d7d3de5879738ff0b9c3ea5e4847fb48cb86
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Degenerative_Proximal_Tubule_Epithelial_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

SIPA1L3 CUBN GRAMD1B PTPRD PKHD1

1.25e-0418711553ae3b8de1a195d4d5057cf3c64fcdb5f48681ce5
DiseaseN-acetylcarnosine measurement

GABRR1 GABRR2 TGFBR2

3.02e-0681133EFO_0022101
Diseaseproliferative diabetic retinopathy

DPP10 CPM PRKAG2 NNT

8.99e-05611134EFO_0009322
Diseasesusceptibility to rheumatic fever measurement

MSH3 RYR3 PTPRD

1.67e-04281133EFO_0008416
DiseaseX-12244--N-acetylcarnosine measurement

GABRR1 TGFBR2

3.01e-0471132EFO_0021299
Diseaseblood N-acetylcarnosine measurement

GABRR1 TGFBR2

3.01e-0471132EFO_0022217
Diseasesevere acute respiratory syndrome, COVID-19

SOX5 MXRA5 WDFY4 TGFBR2 PTPRD SUN3 ATP11A PRKAG2

3.33e-044471138EFO_0000694, MONDO_0100096
DiseaseAlcoholic Intoxication, Chronic

GABRR1 GABRR2 GAD1 HTR2C SERINC2 RACK1

5.96e-042681136C0001973
Diseaseendometrial carcinoma (is_implicated_in)

POLE MSH3

9.36e-04121132DOID:2871 (is_implicated_in)
Diseasemismatch repair cancer syndrome (is_implicated_in)

POLE TGFBR2

9.36e-04121132DOID:0112182 (is_implicated_in)
Diseasesystemic scleroderma (is_marker_for)

CXCR6 C3 IL27RA

1.11e-03531133DOID:418 (is_marker_for)
DiseaseMalformations of Cortical Development

AKT3 DYNC1H1

1.28e-03141132C1955869
DiseaseCortical Dysplasia

AKT3 DYNC1H1

1.28e-03141132C0431380
Diseaserenal cell carcinoma (biomarker_via_orthology)

ANXA2 ANXA2P2

1.28e-03141132DOID:4450 (biomarker_via_orthology)
DiseaseReplication Error Phenotype

MSH3 TGFBR2

1.48e-03151132C1721098
DiseaseMicrosatellite Instability

MSH3 TGFBR2

1.48e-03151132C0920269
Diseasethird ventricle volume measurement

GABRR2 PTPRD

1.48e-03151132EFO_0010335
Diseasecreatinine measurement

SOX5 DCDC1 SLC7A13 SIPA1L3 SERINC2 CUBN AP4E1 FAP PKHD1 PRKAG2 SOS2

1.54e-0399511311EFO_0004518
Diseasesickle cell anemia (is_implicated_in)

APOB C3

1.68e-03161132DOID:10923 (is_implicated_in)
DiseaseSchizophrenia

SOX5 GABRR1 GAD1 HTR2C NUMBL ASAH1 PAFAH1B1 NRG3 PLXNA2 TBX1

2.12e-0388311310C0036341
Diseaseinterstitial lung disease

CWH43 ATP11A NRG3

2.19e-03671133EFO_0004244
DiseaseHydrops Fetalis

ASAH1 SOS2

2.38e-03191132C0020305
Diseasecumulative dose response to bevacizumab

GRAMD1B TGFBR2

2.38e-03191132EFO_0005944
DiseaseDiGeorge syndrome (implicated_via_orthology)

TGFBR2 TBX1

2.38e-03191132DOID:11198 (implicated_via_orthology)
Diseaseuric acid measurement

SOX5 GAD1 DCDC1 SIPA1L3 CUBN FAP PRKAG2 SOS2

2.44e-036101138EFO_0004761
Diseasewhite matter lesion progression measurement

FNDC1 NRG3 TBX1

2.59e-03711133EFO_0007746
DiseaseEndometrial Carcinoma

POLE MSH3 HSD17B2

2.69e-03721133C0476089
DiseaseRetinal Degeneration

NMNAT1 IFT80

2.91e-03211132C0035304
DiseaseArthrogryposis

VPS8 DYNC1H1

2.91e-03211132C0003886
DiseaseLiver Cirrhosis, Experimental

ANXA2 PFKP RMDN2 AQP7 TGFBR2 MTMR7 PTPRD ASAH1 HSD17B2

2.97e-037741139C0023893
Diseasecortical thickness

SOX5 AKT3 DCDC1 MSH3 CPM PAFAH1B1 KCNK2 PKHD1 PRKAG2 PLXNA2 SOS2

3.66e-03111311311EFO_0004840
Diseaselung squamous cell carcinoma (is_implicated_in)

POLE KMT2D

3.80e-03241132DOID:3907 (is_implicated_in)

Protein segments in the cluster

PeptideGeneStartEntry
LWESKKQSFVGMLTI

PRKAG2

306

Q9UGJ0
QAKRMTWGKVTSLLI

CXCR6

141

O00574
AIVNKTVWDLMVGAK

DNM1P46

66

Q6ZS02
MAGRKLALKTIDWVA

ATP5PD

1

O75947
NSRTKAIMKIAIVWA

HTR2C

166

P28335
TWEILAVSMSDKKGI

C3

801

P01024
TWIDTSTGKKVKMQR

ABHD4

291

Q8TB40
KGTDVPKWISIMTER

ANXA2

206

P07355
LGKKDVMWIGFLTRT

ASAH1

241

Q13510
KGTDVPKWISIMTER

ANXA2P2

206

A6NMY6
ITMVKWVSNTKTVVR

DPP10

321

Q8N608
VLVLQSMWKGKTLRR

ASPM

1951

Q8IZT6
TELQKWREIIKSSVM

GRAMD1B

691

Q3KR37
MSDVTIVKEGWVQKR

AKT3

1

Q9Y243
LMVWSVTNKSGLELK

AP4E1

941

Q9UPM8
VVGMTKSKVLAVSLW

NWD2

1451

Q9ULI1
LKAMGRKSVKSVLWV

NUMBL

106

Q9Y6R0
MKEIKGRTVAVDWAV

RBM28

176

Q9NW13
ILSASRDKTIIMWKL

RACK1

31

P63244
LLSGSRDKTIKMWDV

PAFAH1B1

311

P43034
LKSSWVRTVLLGVME

KIAA1549

1166

Q9HCM3
LSLMLLKWIVVGSVK

NRG3

81

P56975
QTDMKTKGSLLWVLD

MSH3

551

P20585
TSKWVGEGEKMVRAL

FIGNL1

471

Q6PIW4
VWLITKTGMILSRAI

DCDC1

701

M0R2J8
TLKEGRSKTMVIWIE

MOV10L1

281

Q9BXT6
RSKTMVIWIENKGDI

MOV10L1

286

Q9BXT6
IMGNSAKEALVWKVL

MAGEH1

101

Q9H213
KSKKVVEVWIGMTIE

MTIF2

86

P46199
RTLKGFMVLIEKDWI

MTMR7

361

Q9Y216
GTGKTTLARKMVLDW

NLRP10

176

Q86W26
WMKSSLEEGISVLKS

MTO1

531

Q9Y2Z2
LSWITETEKKLMSLG

DST

5841

Q03001
TRGSKMVSWSVIAKI

AQP7P3

11

A6NL99
TRGSKMVSWSVIAKI

AQP7B

11

A0A075B734
MIGDWLRVISKKTKE

KCNK2

306

O95069
EQITLKKMREIVGWS

GAD1

226

Q99259
VIESKKTVMEGWVKV

HTD2

146

P86397
TTKIEGDWKRLNTLM

PLXNA2

1571

O75051
ILVTVWLKSSAAMAK

OR4K5

221

Q8NGD3
GTKISARAMEWITAK

PFKP

686

Q01813
QLTMSDKLLVWGTKA

IL27RA

96

Q6UWB1
VKMVQVWRDISLTKF

CLC

121

Q05315
WRMSVAKTSVDILKI

KNTC1

951

P50748
SMIGDWLRVLSKKTK

KCNK10

316

P57789
TRGSKMVSWSVIAKI

AQP7

11

O14520
MAGVKLTDKVKLTWR

ANO1

496

Q5XXA6
IKVWMLTGDKLETAT

ATP9A

671

O75110
TFRILKSMVVGWVKE

POLE

1791

Q07864
LVSLKKWMLEGQVDS

ITFG2

171

Q969R8
FWVIKTEMGKVLRIT

CUBN

501

O60494
VGSKLIVAMSSWLQK

APOB

1226

P04114
LSMTFDGRLVKKIWV

GABRR1

141

P24046
KIWSKTGMLRSTLAQ

IFT80

131

Q9P2H3
TVAVMKWLKTETFVL

CPM

171

P14384
VKLLSTKMGLKVTWD

FNDC1

46

Q4ZHG4
TEGVKWTPSKMIARL

DHPS

196

P49366
DGWIGVRSVMLKKSL

MTFMT

326

Q96DP5
TLQDRTEKMKEIVGW

FBXO24

531

O75426
EATRKIWMVDSKGLI

ME3

361

Q16798
IWMVDSKGLIVKGRS

ME3

366

Q16798
WLTLVEKEMRVTLAK

DYNC1H1

1701

Q14204
IVIWGTLSIMRSMKS

SPAM1

336

P38567
TSVGSMKVLRGIWVA

CRYBG1

1261

Q9Y4K1
MRLELSKWGIKVASI

HSD17B2

246

P37059
IDMVKSKWGLALAAV

SCAP

306

Q12770
SMIHVQKWLGKETTI

FABP9

91

Q0Z7S8
KSMTFDGRLVKKIWV

GABRR2

121

P28476
VKAVMKTSVLLSWEI

PTPRD

1026

P23468
EVWKSKQVIVMKRSL

NNT

1031

Q13423
KKWMLTLLRIITIGS

CWH43

66

Q9H720
WMLIGETLKNMVKST

UTP20

266

O75691
ISSVRGKAMKKWVES

SOS2

716

Q07890
RSIKEKISMWTALFT

SLC35G2

276

Q8TBE7
IVQRLKVMTSGWETV

SIPA1L3

951

O60292
KLSSTWETGKTRKLM

TGFBR2

196

P37173
VSKLSWIEKKMAATL

RMDN2

316

Q96LZ7
ILVIGLKPSLKVWMT

VPS8

326

Q8N3P4
SSGIKTPKRWELMVS

PKHD1

2456

P08F94
ISKRLGAEWKVMSEA

SOX1

81

O00570
KVVRTESLLGLWKGM

SLC25A38

76

Q96DW6
MKILGVWDTAVSLGK

ASPRV1

251

Q53RT3
GVLIDLWKITKVMDV

CLPTM1

426

O96005
TNWKRVMIVLSGSLL

CHST12

176

Q9NRB3
NWKRVMKVLAGVLDS

CHST14

161

Q8NCH0
IKVWVLTGDKMETAA

ATP11A

681

P98196
LKVWVLTGDKMETAK

ATP11C

671

Q8NB49
IGKTTLLRKVMLDWA

NLRP9

156

Q7RTR0
MKTWVKIVFGVATSA

FAP

1

Q12884
KKTKWTVGVVRESII

TRIM69

386

Q86WT6
SLKVIWKVMSILKGR

TAS2R7

296

Q9NYW3
LLTSGTDKVIKLWDM

WDFY2

381

Q96P53
MAESGKEKIKWTTTI

SPO16

1

Q5VVC0
LKTMLAVGWTVERTK

RYR3

2676

Q15413
RKGTVLIWQKVDEVM

THG1L

236

Q9NWX6
IVSSGGDLTVKMWRV

WDR97

611

A6NE52
GVTRSWKIILSTMLT

SUN3

41

Q8TAQ9
QWMVGVKRLIAEKRS

SRA1

181

Q9HD15
MATKTAGVGRWEVVK

TMEM214

1

Q6NUQ4
VRVWKTEDVKMSVPG

WDFY4

3096

Q6ZS81
QLLASGMKEVTRTWK

TMEM38B

111

Q9NVV0
MLWIVGILTSRGVKE

SLC7A13

141

Q8TCU3
ISKILGSRWKAMTNL

SOX5

586

P35711
EMTQVKEVKGLEWRT

SUOX

271

P51687
KVAGVSVQLEMKALW

TBX1

106

O43435
GARVIVTDTWVMKVT

TMEM129

161

A0AVI4
KTSRIWSLEGKSIMT

WDR12

121

Q9GZL7
KLLKAGWSREEITME

TOR3A

286

Q9H497
TRLITAVVMKNWKEI

SEC31A

626

O94979
KMTDTSEKPLWRTVL

SLC5A1

631

P13866
KPGETRKMISTWTAV

SERINC2

411

Q96SA4
MAGKVKWVTDIEKSV

TTLL1

1

O95922
VIVDMRGSKWDSIKP

TRIO

126

O75962
SKITKVMLLKGWRCV

KMT2D

1411

O14686
GVGKTTLVRKAMLDW

NLRP14

186

Q86W24
MWPEGKLSITEVTKR

MYO1D

546

O94832
KFSILSSGWLRIKSM

MXRA5

531

Q9NR99
RVIMAELATKNSKWV

NMNAT1

66

Q9HAN9