Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionG protein-coupled receptor activity

OR51G2 S1PR5 HTR1B OR14A2 GPR37 OR6C4 NTSR1 GPR78 OR13H1 GPR45 CXCR1

1.39e-048846611GO:0004930
GeneOntologyBiologicalProcessmaintenance of location in cell

HEXB IL13 NTSR1 OS9 TMED2 CCL21 ADCY6

1.38e-05259637GO:0051651
GeneOntologyBiologicalProcessG protein-coupled receptor signaling pathway

OR51G2 S1PR5 DEFB1 HTR1B OR14A2 GPR37 OR6C4 NTSR1 GPR78 OR13H1 CCL20 CCL21 ADCY6 GPR45 CXCR1

1.46e-0513956315GO:0007186
GeneOntologyBiologicalProcessmaintenance of location

HEXB IL13 MOSPD2 NTSR1 OS9 TMED2 CCL21 ADCY6

2.65e-05396638GO:0051235
GeneOntologyBiologicalProcesscellular response to temperature stimulus

HTR1B KCNK4

9.13e-055632GO:0071502
GeneOntologyCellularComponentcell surface

IL13 LRRC24 MUC17 GPR37 ADAM15 B2M NTSR1 DCSTAMP CCL21 BTNL9 CRLF2 PTPRT CXCR1

3.71e-0511116613GO:0009986
GeneOntologyCellularComponentexternal side of plasma membrane

IL13 LRRC24 MUC17 B2M CCL21 BTNL9 CRLF2 CXCR1

2.22e-04519668GO:0009897
GeneOntologyCellularComponentnuclear outer membrane-endoplasmic reticulum membrane network

RNF186 MOSPD2 ERGIC3 CYP2F1 GPR37 B2M RGPD1 OS9 TMED2 TMEM119 DCSTAMP TMBIM6 STT3A

2.23e-0413276613GO:0042175
GeneOntologyCellularComponentside of membrane

IL13 LRRC24 MUC17 B2M NTSR1 PRSS55 CCL21 BTNL9 CRLF2 CXCR1

3.94e-048756610GO:0098552
GeneOntologyCellularComponentendoplasmic reticulum membrane

RNF186 MOSPD2 ERGIC3 CYP2F1 GPR37 B2M OS9 TMED2 TMEM119 DCSTAMP TMBIM6 STT3A

6.53e-0412936612GO:0005789
GeneOntologyCellularComponentendoplasmic reticulum subcompartment

RNF186 MOSPD2 ERGIC3 CYP2F1 GPR37 B2M OS9 TMED2 TMEM119 DCSTAMP TMBIM6 STT3A

6.80e-0412996612GO:0098827
GeneOntologyCellularComponentsecretory granule

HEXB MOSPD2 MS4A3 ABCA12 ADAM15 B2M PRSS55 SERPING1 TMED2 CXCR1

1.23e-0310146610GO:0030141
DomainHMGI/Y_DNA-bd_CS

PRB1 PRB3 PRB4 PRB2

3.92e-0631654IPR000637
DomainPro-rich

PRR4 PRB1

3.57e-053652SM01412
DomainPro-rich

PRR4 PRB1

3.57e-053652IPR026086
DomainPro-rich

PRR4 PRB1

3.57e-053652PF15240
DomainGPCR_Rhodpsn_7TM

OR51G2 S1PR5 HTR1B GPR37 OR6C4 NTSR1 GPR78 OR13H1 GPR45 CXCR1

9.94e-056706510IPR017452
Domain7tm_1

OR51G2 S1PR5 HTR1B GPR37 OR6C4 NTSR1 GPR78 OR13H1 GPR45 CXCR1

1.08e-046776510PF00001
DomainG_PROTEIN_RECEP_F1_1

OR51G2 S1PR5 HTR1B GPR37 OR6C4 NTSR1 GPR78 OR13H1 GPR45 CXCR1

1.19e-046856510PS00237
DomainG_PROTEIN_RECEP_F1_2

OR51G2 S1PR5 HTR1B GPR37 OR6C4 NTSR1 GPR78 OR13H1 GPR45 CXCR1

1.28e-046916510PS50262
DomainGPCR_Rhodpsn

OR51G2 S1PR5 HTR1B GPR37 OR6C4 NTSR1 GPR78 OR13H1 GPR45 CXCR1

1.30e-046926510IPR000276
DomainSMALL_CYTOKINES_CC

CCL20 CCL21

3.67e-0326652PS00472
DomainChemokine_CC_CS

CCL20 CCL21

3.67e-0326652IPR000827
PathwayREACTOME_G_ALPHA_I_SIGNALLING_EVENTS

S1PR5 HTR1B GPR37 CCL20 CCL21 ADCY6 CXCR1

9.73e-05289537MM15057
PathwayREACTOME_G_ALPHA_I_SIGNALLING_EVENTS

S1PR5 HTR1B GPR37 CCL20 CCL21 ADCY6 CXCR1

1.63e-04314537M600
PathwayREACTOME_CLASS_A_1_RHODOPSIN_LIKE_RECEPTORS

S1PR5 HTR1B GPR37 NTSR1 CCL20 CCL21 CXCR1

2.21e-04330537M18334
PathwayREACTOME_CLASS_A_1_RHODOPSIN_LIKE_RECEPTORS

S1PR5 HTR1B GPR37 NTSR1 CCL20 CCL21 CXCR1

2.33e-04333537MM14963
Pubmed

The involvement of proline-rich protein Mus musculus predicted gene 4736 in ocular surface functions.

PRB1 PRB3 PRB4 PRB2

1.18e-11466427588265
Pubmed

Length polymorphisms in human proline-rich protein genes generated by intragenic unequal crossing over.

PRB1 PRB3 PRB4 PRB2

1.18e-1146642851479
Pubmed

Differential RNA splicing and post-translational cleavages in the human salivary proline-rich protein gene system.

PRB1 PRB3 PRB4 PRB2

1.77e-1066642993301
Pubmed

Molecular genetics of human salivary proteins and their polymorphisms.

PRB1 PRB3 PRB4

6.53e-0936633055850
Pubmed

The structure and evolution of the human salivary proline-rich protein gene family.

PRB1 PRB4 PRB2

6.53e-0936638422499
Pubmed

cDNA clones for mouse parotid proline-rich proteins. mRNA regulation by isoprenaline and the nucleotide sequence of proline-rich protein cDNA MP5.

PRB1 PRB3 PRB4

2.61e-0846631339347
Pubmed

The intriguing heterogeneity of human salivary proline-rich proteins: Short title: Salivary proline-rich protein species.

PRB3 PRB4 PRB2

6.51e-08566326375204
Pubmed

Dissociation of heterotrimeric g proteins in cells.

S1PR5 HTR1B NTSR1 CCL20 CCL21 CXCR1

1.20e-0617966618577758
Pubmed

Salivary proline-rich proteins.

PRB1 PRB4

3.55e-0626626810092
Pubmed

PRB1, PRB2, and PRB4 coded polymorphisms among human salivary concanavalin-A binding, II-1, and Po proline-rich proteins.

PRB4 PRB2

3.55e-0626628554050
Pubmed

Identification of Lys-Pro-Gln as a novel cleavage site specificity of saliva-associated proteases.

PRB3 PRB4

3.55e-06266218463091
Pubmed

Enhanced glycosylation and sulfation of secretory proteoglycans is coupled to the expression of a basic secretory protein.

PRB1 PRB4

3.55e-0626629487127
Pubmed

Fractionation and characterization of basic proline-rich peptides of human parotid saliva and the amino acid sequence of proline-rich peptide P-E.

PRB1 PRB2

3.55e-0626627118863
Pubmed

Basic proline-rich proteins from human parotid saliva: complete covalent structure of protein IB-9 and partial structure of protein IB-6, members of a polymorphic pair.

PRB1 PRB2

3.55e-0626626924859
Pubmed

Clones from the human gene complex coding for salivary proline-rich proteins.

PRB1 PRB2

3.55e-0626626089212
Pubmed

NANOS2 promotes male germ cell development independent of meiosis suppression.

PRB3 PRB4 PRB2

5.22e-061866324183939
Pubmed

OS9 interacts with DC-STAMP and modulates its intracellular localization in response to TLR ligation.

OS9 DCSTAMP

1.06e-05366218952287
Pubmed

The Role of TSLP in IL-13-induced atopic march.

IL13 CRLF2

1.06e-05366222355542
Pubmed

Thymic stromal lymphopoietin-induced human asthmatic airway epithelial cell proliferation through an IL-13-dependent pathway.

IL13 CRLF2

1.06e-05366220236697
Pubmed

Deficient human β-defensin 1 underlies male infertility associated with poor sperm motility and genital tract infection.

DEFB1 CCL20

1.06e-05366225122636
Pubmed

IL-13 induces skin fibrosis in atopic dermatitis by thymic stromal lymphopoietin.

IL13 CRLF2

1.06e-05366221576506
Pubmed

The structure of human macrophage inflammatory protein-3alpha /CCL20. Linking antimicrobial and CC chemokine receptor-6-binding activities with human beta-defensins.

DEFB1 CCL20

1.06e-05366212149255
Pubmed

Proteolytic processing of a human salivary proline-rich protein precursor by proprotein convertases.

PRB1 PRB4

1.06e-05366211422372
Pubmed

Essential role of CCL21 in establishment of central self-tolerance in T cells.

B2M CCL21

1.06e-05366228611158
Pubmed

Induction of functional IL-8 receptors by IL-4 and IL-13 in human monocytes.

IL13 CXCR1

2.12e-05466210725748
Pubmed

Finding new posttranslational modifications in salivary proline-rich proteins.

PRB3 PRB4

2.12e-05466220879038
Pubmed

Fate mapping of Spp1 expression reveals age-dependent plasticity of disease-associated microglia-like cells after brain injury.

MS4A3 TMEM119

2.12e-05466238309272
Pubmed

DC-STAMP interacts with ER-resident transcription factor LUMAN which becomes activated during DC maturation.

OS9 DCSTAMP

2.12e-05466220546900
Pubmed

Basic proline-rich proteins from human parotid saliva: relationships of the covalent structures of ten proteins from a single individual.

PRB4 PRB2

2.12e-0546621849422
Pubmed

Beta-defensins: linking innate and adaptive immunity through dendritic and T cell CCR6.

DEFB1 CCL20

2.12e-05466210521347
Pubmed

CCR7 signals are essential for cortex-medulla migration of developing thymocytes.

B2M CCL21

3.53e-05566215302902
Pubmed

Basophil-derived interleukin-4 controls the function of natural helper cells, a member of ILC2s, in lung inflammation.

IL13 CRLF2

3.53e-05566224837103
Pubmed

Redefining the ontogeny of hyalocytes as yolk sac-derived tissue-resident macrophages of the vitreous body.

HEXB TMEM119

3.53e-05566238961498
Pubmed

Critical link between TRAIL and CCL20 for the activation of TH2 cells and the expression of allergic airway disease.

IL13 CCL20

3.53e-05566217934471
Pubmed

T helper cell IL-4 drives intestinal Th2 priming to oral peanut antigen, under the control of OX40L and independent of innate-like lymphocytes.

IL13 B2M

3.53e-05566224781052
Pubmed

Thymic stromal lymphopoietin amplifies the differentiation of alternatively activated macrophages.

IL13 CRLF2

5.29e-05666223275605
Pubmed

Flexible Accelerated STOP Tetracycline Operator-knockin (FAST): a versatile and efficient new gene modulating system.

HTR1B MLC1

5.29e-05666220163789
Pubmed

IL-25 and type 2 innate lymphoid cells induce pulmonary fibrosis.

IL13 CRLF2

5.29e-05666224344271
Pubmed

A comparative analysis of microglial inducible Cre lines.

HEXB TMEM119

7.40e-05766237635351
Pubmed

Polymorphisms in PARP, IL1B, IL4, IL10, C1INH, DEFB1, and DEFA4 in meningococcal disease in three populations.

DEFB1 SERPING1

7.40e-05766220016407
Pubmed

IL-33, but not thymic stromal lymphopoietin or IL-25, is central to mite and peanut allergic sensitization.

IL13 CRLF2

7.40e-05766223006545
Pubmed

Tissue signals imprint ILC2 identity with anticipatory function.

IL13 CRLF2

7.40e-05766230201992
Pubmed

Dermis resident macrophages orchestrate localized ILC2 eosinophil circuitries to promote non-healing cutaneous leishmaniasis.

IL13 CRLF2

9.86e-05866238030609
Pubmed

IL-33 and thymic stromal lymphopoietin mediate immune pathology in response to chronic airborne allergen exposure.

IL13 CRLF2

9.86e-05866225015831
Pubmed

MafB-restricted local monocyte proliferation precedes lung interstitial macrophage differentiation.

MS4A3 TMEM119

1.27e-04966236928411
Pubmed

Homeostatic IL-13 in healthy skin directs dendritic cell differentiation to promote TH2 and inhibit TH17 cell polarization.

IL13 CRLF2

1.27e-04966234795444
Pubmed

IL-33, IL-25 and TSLP contribute to development of fungal-associated protease-induced innate-type airway inflammation.

IL13 CRLF2

1.58e-041066230575775
Pubmed

TRAIL deficiency and PP2A activation with salmeterol ameliorates egg allergen-driven eosinophilic esophagitis.

IL13 CCL20

1.58e-041066227742702
Pubmed

CISH constrains the tuft-ILC2 circuit to set epithelial and immune tone.

IL13 CRLF2

1.58e-041066234290377
Pubmed

Airway uric acid is a sensor of inhaled protease allergens and initiates type 2 immune responses in respiratory mucosa.

IL13 CRLF2

1.58e-041066224663677
Pubmed

New genetic associations detected in a host response study to hepatitis B vaccine.

DEFB1 IL13 MS4A3 GPR37 B2M SERPING1 CCL20 CXCR1

1.64e-0482466820237496
Pubmed

Multilevel proteomics reveals host perturbations by SARS-CoV-2 and SARS-CoV.

S1PR5 MOSPD2 GPR37 B2M TMED2 STRA6 ADCY6 RUSF1 STT3A

1.72e-04106166933845483
Pubmed

Versican interacts with chemokines and modulates cellular responses.

CCL20 CCL21

1.93e-041166211083865
Pubmed

The Additive Inflammatory In Vivo and In Vitro Effects of IL-7 and TSLP in Arthritis Underscore the Therapeutic Rationale for Dual Blockade.

IL13 CRLF2

1.93e-041166226110994
Pubmed

Tuft-cell-derived IL-25 regulates an intestinal ILC2-epithelial response circuit.

IL13 CRLF2

1.93e-041166226675736
Pubmed

A Novel GLP1 Receptor Interacting Protein ATP6ap2 Regulates Insulin Secretion in Pancreatic Beta Cells.

ERGIC3 B2M TMBIM6

2.07e-046066326272612
Pubmed

Epithelial-stromal interaction via Notch signaling is essential for the full maturation of gut-associated lymphoid tissues.

CCL20 CCL21

2.31e-041266225378482
Pubmed

A tissue checkpoint regulates type 2 immunity.

IL13 CRLF2

2.31e-041266227749840
Pubmed

A type 2 immune circuit in the stomach controls mammalian adaptation to dietary chitin.

IL13 CRLF2

2.73e-041366237676935
Pubmed

CD40 Mediates Maturation of Thymic Dendritic Cells Driven by Self-Reactive CD4+ Thymocytes and Supports Development of Natural Regulatory T Cells.

B2M CRLF2

2.73e-041366229321275
Pubmed

TGFβ attenuates cartilage extracellular matrix degradation via enhancing FBXO6-mediated MMP14 ubiquitination.

ERGIC3 ADAM15 OS9 STT3A

2.74e-0416466432409323
Pubmed

Comprehensive copy number variant (CNV) analysis of neuronal pathways genes in psychiatric disorders identifies rare variants within patients.

HTR1B NTSR1 SDK1

2.87e-046766320398908
Pubmed

Innate type 2 immunity controls hair follicle commensalism by Demodex mites.

IL13 CRLF2

3.18e-041466236044899
Pubmed

Chitin activates parallel immune modules that direct distinct inflammatory responses via innate lymphoid type 2 and γδ T cells.

IL13 CRLF2

3.18e-041466224631157
Pubmed

HIV type 1 glycoprotein 120 inhibits human B cell chemotaxis to CXC chemokine ligand (CXCL) 12, CC chemokine ligand (CCL)20, and CCL21.

CCL20 CCL21

3.18e-041466215972662
Pubmed

Presence of three distinct molecular species of Gi protein alpha subunit. Structure of rat cDNAs and human genomic DNAs.

S1PR5 HTR1B CXCR1

4.00e-04756632834384
Pubmed

ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1.

HEXB MOSPD2 ERGIC3 ADAM15 TMED2 LRP1B RUSF1 STT3A TPCN1

4.28e-04120166935696571
Pubmed

Natural selection on the olfactory receptor gene family in humans and chimpanzees.

OR51G2 OR13H1

4.74e-041766212908129
Pubmed

An antibody-based proximity labeling map reveals mechanisms of SARS-CoV-2 inhibition of antiviral immunity.

CUL4B MOSPD2 ADAM15 OS9 ESPL1 RUSF1 STT3A

4.76e-0473366734672954
Pubmed

Identification of ectodysplasin target genes reveals the involvement of chemokines in hair development.

CCL20 CXCR1

5.32e-041866222277947
Pubmed

Reviews in molecular biology and biotechnology: transmembrane signaling by G protein-coupled receptors.

HTR1B CCL20 CCL21 CXCR1

5.79e-0420066418240029
Pubmed

Spatial and temporal heterogeneity of mouse and human microglia at single-cell resolution.

CST1 TMEM119

5.94e-041966230760929
Pubmed

Polymorphisms in innate immunity genes and risk of childhood leukemia.

DEFB1 SERPING1 CCL20 CXCR1

6.47e-0420666420438785
Pubmed

Risk of meningioma and common variation in genes related to innate immunity.

DEFB1 SERPING1 CCL20 CXCR1

6.58e-0420766420406964
Pubmed

CBAP functions as a novel component in chemokine-induced ZAP70-mediated T-cell adhesion and migration.

CCL20 CCL21

6.59e-042066223620790
Pubmed

Fine mapping of collagen-induced arthritis quantitative trait loci in an advanced intercross line.

B2M TPCN1

6.59e-042066217082620
Pubmed

Fibroblastic reticular cell lineage convergence in Peyer's patches governs intestinal immunity.

CCL20 CCL21

6.59e-042066233707780
Pubmed

Common variation in genes related to innate immunity and risk of adult glioma.

DEFB1 SERPING1 CCL20 CXCR1

6.70e-0420866419423540
Pubmed

Many chemokines including CCL20/MIP-3alpha display antimicrobial activity.

CCL20 CCL21

7.28e-042166212949249
Pubmed

Variants in inflammation genes and the risk of biliary tract cancers and stones: a population-based study in China.

IL13 CXCR1

7.99e-042266218676870
Pubmed

Shotgun proteomics reveals specific modulated protein patterns in tears of patients with primary open angle glaucoma naïve to therapy.

PRR4 B2M CST1

8.22e-049666323580065
Pubmed

Genome-wide association study of chronic periodontitis in a general German population.

PRB2 LRP1B PTPRT

8.22e-049666324024966
Pubmed

Mesenchymal expression of Foxl1, a winged helix transcriptional factor, regulates generation and maintenance of gut-associated lymphoid organs.

IL13 CCL21

8.75e-042366212648490
Pubmed

Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.

CUL4B MLC1 ADCY6 TPCN1

8.98e-0422566412168954
Pubmed

Proteomics of endoplasmic reticulum-Golgi intermediate compartment (ERGIC) membranes from brefeldin A-treated HepG2 cells identifies ERGIC-32, a new cycling protein that interacts with human Erv46.

ERGIC3 TMED2

9.53e-042466215308636
Pubmed

Cytokine and cytokine receptor single-nucleotide polymorphisms predict risk for non-small cell lung cancer among women.

IL13 CXCR1

1.12e-032666219505916
Pubmed

Modulation of cytokine release and gene expression by the immunosuppressive domain of gp41 of HIV-1.

IL13 SERPING1 CCL20

1.16e-0310866323383108
Pubmed

A subpopulation of embryonic microglia respond to maternal stress and influence nearby neural progenitors.

HEXB TMEM119

1.21e-032766233887203
Pubmed

Extracellular matrix secretion by cardiac fibroblasts: role of microRNA-29b and microRNA-30c.

ADAM15 B2M CST1 SERPING1

1.29e-0324866424006456
Pubmed

Candidate gene analysis in an on-going genome-wide association study of attention-deficit hyperactivity disorder: suggestive association signals in ADRA1A.

DOCK3 HTR1B

1.30e-032866219352218
Pubmed

Signal sequence and keyword trap in silico for selection of full-length human cDNAs encoding secretion or membrane proteins from oligo-capped cDNA libraries.

S1PR5 ERGIC3 ADAM15 TMEM119 C16orf89

1.36e-0343066516303743
Pubmed

CC chemokine ligand 20 (CCL20) positively regulates collagen type I production in 3D skin equivalent tissues.

CCL20 CCL21

1.39e-032966236398464
Pubmed

Defining the membrane proteome of NK cells.

HEXB MOSPD2 ERGIC3 B2M MARF1 TMBIM6 RUSF1 STT3A

1.62e-03116866819946888
Pubmed

Role of inflammation gene polymorphisms on pain severity in lung cancer patients.

IL13 CXCR1

1.80e-033366219773451
InteractionTMEM107 interactions

GJA5 ERGIC3 MS4A3 PDZK1IP1 CCL21

5.44e-0752625int:TMEM107
InteractionTMEM140 interactions

ERGIC3 MS4A3 PDZK1IP1 TMEM140

3.26e-0559624int:TMEM140
InteractionTMEM106B interactions

HEXB ERGIC3 ADAM15 B2M OS9 TMED2 STT3A

4.45e-05309627int:TMEM106B
InteractionIGFBP5 interactions

GJA5 ERGIC3 MS4A3 PDZK1IP1 CXCR1

4.80e-05129625int:IGFBP5
InteractionDCSTAMP interactions

OS9 DCSTAMP

5.57e-054622int:DCSTAMP
InteractionODF4 interactions

TMEM119 TMBIM6 RUSF1

7.69e-0527623int:ODF4
InteractionMZT2B interactions

MLC1 BTNL9 GPR45 RUSF1

7.95e-0574624int:MZT2B
Cytoband12p13.2

PRB1 PRB3 PRB4 PRB2

5.55e-074566412p13.2
Cytoband12q12-q13

TMBIM6 ADCY6

5.67e-05866212q12-q13
CytobandEnsembl 112 genes in cytogenetic band chr12p13

PRR4 PRB1 PRB3 PRB4 PRB2

1.59e-04353665chr12p13
CytobandEnsembl 112 genes in cytogenetic band chr12q13

OR6C4 OS9 TMBIM6 ESPL1 ADCY6

3.65e-04423665chr12q13
Cytoband9q31.1

SMC2 TEX10

1.61e-03416629q31.1
GeneFamilyProline rich proteins

PRB1 PRB3 PRB4 PRB2

8.39e-106514972
GeneFamilyG protein-coupled receptors, Class A orphans

GPR37 GPR78 GPR45

1.39e-0378513262
CoexpressionMIKKELSEN_MEF_LCP_WITH_H3K27ME3

GJA5 PDZK1IP1 STRA6 BTNL9 C16orf89

7.25e-0771625M1965
CoexpressionMIKKELSEN_MEF_LCP_WITH_H3K27ME3

GJA5 PDZK1IP1 STRA6 BTNL9 C16orf89

1.09e-0677625MM839
CoexpressionTRAVAGLINI_LUNG_SEROUS_CELL

PRR4 PRB1 PRB3 PRB4 PRB2

3.25e-0696625M41657
CoexpressionFULLER_PBMC_F_TULARENSIS_VACCINE_LVS_AGE_22_54YO_48HR_UP

B2M CCL20 DCSTAMP CCL21

1.25e-0560624M40883
CoexpressionFULLER_PBMC_F_TULARENSIS_VACCINE_LVS_AGE_22_54YO_18HR_DN

B2M CCL20 CCL21

1.63e-0521623M40919
CoexpressionFAN_OVARY_CL16_LYMPHATIC_ENDOTHELIAL_CELL

HEXB B2M SERPING1 OS9 CCL21 TMBIM6

1.83e-05232626M41718
CoexpressionTABULA_MURIS_SENIS_MESENTERIC_ADIPOSE_TISSUE_CD4_POSITIVE_ALPHA_BETA_T_CELL_AGEING

HEXB B2M CST1 MARF1

2.59e-0572624MM3778
CoexpressionTABULA_MURIS_SENIS_MESENTERIC_ADIPOSE_TISSUE_B_CELL_AGEING

HEXB CST1 SERPING1 CRLF2

4.32e-0582624MM3777
CoexpressionFULLER_PBMC_F_TULARENSIS_VACCINE_LVS_AGE_22_54YO_336HR_DN

B2M CCL20 DCSTAMP

5.95e-0532623M40918
CoexpressionSENGUPTA_NASOPHARYNGEAL_CARCINOMA_WITH_LMP1_DN

PRR4 DEFB1 ABCA12 PDZK1IP1 BTNL9

5.96e-05175625M6750
CoexpressionFULLER_PBMC_F_TULARENSIS_VACCINE_LVS_AGE_22_54YO_192HR_DN

B2M CCL20 DCSTAMP

6.54e-0533623M40917
CoexpressionYAMAZAKI_TCEB3_TARGETS_UP

B2M CST1 SERPING1 TMED2 STRA6

6.63e-05179625MM660
CoexpressionLUI_TARGETS_OF_PAX8_PPARG_FUSION

ERGIC3 B2M TMBIM6

7.16e-0534623M13314
CoexpressionTABULA_MURIS_SENIS_BROWN_ADIPOSE_TISSUE_B_CELL_AGEING

HEXB B2M CST1 SERPING1 OS9 CRLF2

9.35e-05311626MM3674
CoexpressionHE_LIM_SUN_FETAL_LUNG_C2_GMP_CELL

DEFB1 MS4A3 MLC1

1.26e-0441623M45727
CoexpressionMARTENS_TRETINOIN_RESPONSE_UP

IL13 GJA5 SLC7A4 RNF186 HTR1B CCL20 STRA6 DCSTAMP CXCR1

1.73e-04855629M2098
CoexpressionLUI_THYROID_CANCER_PAX8_PPARG_DN

ERGIC3 B2M TMBIM6

1.78e-0446623M4902
CoexpressionVAN_DEN_BIGGELAAR_PBMC_PREVNAR_9MO_INFANT_STIMULATED_VS_UNSTIMULATED_9MO_UP

IL13 MLC1 SERPING1 ESPL1

2.36e-04127624M40952
CoexpressionAtlassalivary gland

PRR4 PRB1 PRB3 PRB4 PRB2 CST1

1.69e-0783636salivary gland
CoexpressionAtlasdev lower uro neuro_e14.5_PelvicGanglion_Sox10_k-means-cluster#4_top-relative-expression-ranked_100

GJA5 TMEM119 STRA6

6.16e-0526633gudmap_dev lower uro neuro_e14.5_PelvicGanglion_Sox10_k4_100
CoexpressionAtlascervix, uterine

DEFB1 RGPD1 TMEM119 STRA6 SDK1

8.06e-05149635cervix, uterine
CoexpressionAtlaskidney_adult_CortVasc_Tie2_top-relative-expression-ranked_200

DEFB1 GJA5 MOSPD2 TMEM140 C16orf89

1.19e-04162635gudmap_kidney_adult_CortVasc_Tie2_200
ToppCellcellseq-Epithelial-Epithelial_Glandular|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

PRR4 CYP2F1 PRB1 PRB3 PRB4 PDZK1IP1 PRB2 CST1 STRA6

1.28e-11194669d0fb1ff5cf0738881e114a58f0b27489f781d72b
ToppCell5'-Parenchyma_lung-Epithelial-Epithelial_transtional-secretory-club_cell-Club_(non-nasal)-Club_(non-nasal)_L.0.4.0.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

PRR4 CYP2F1 PRB1 PRB2 CST1 STRA6 SDK1 C16orf89

3.29e-101856685dee5645240637e135677732a35fd416b37367d4
ToppCellSerous|World / shred by cell class for bronchial biopsy

PRR4 PRB1 PRB3 PRB4 PDZK1IP1 PRB2 C16orf89

1.08e-0818466709d0d1525c11dd326efd942684c03f79d992cf3b
ToppCell3'-Airway_Nasal-Epithelial-Epithelial_transtional-secretory-SMG_serous_secreting_cell-SMG_serous_(nasal)-SMG_serous_(nasal)_L.0.6.0.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

PRR4 PRB1 PRB3 PRB4 PDZK1IP1 PRB2 TMED2

1.26e-0818866702b3aae071ff1f469d52a4d513a4eb46ae70bba3
ToppCell3'-Broncho-tracheal_SMG-Epithelial-Epithelial_transtional-secretory-SMG_tracheobronchial_serous_cell-SMG_serous_(bronchial)|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

PRR4 PRB1 PRB3 PRB4 PDZK1IP1 PRB2 TMED2

1.51e-0819366756145861ef5e7655db9ad0d11b82f72dcadf285d
ToppCell3'-Broncho-tracheal_SMG-Epithelial-Epithelial_transtional-secretory-SMG_tracheobronchial_serous_cell|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

PRR4 PRB1 PRB3 PRB4 PDZK1IP1 PRB2 TMED2

1.51e-081936673d1710a6060d3a70994a206334ccb16cd63e5f20
ToppCellTracheal-10x3prime_v2-Epithelial-Epi_submucosal-gland|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

PRR4 DEFB1 PRB1 PRB3 PRB4 PDZK1IP1 PRB2

1.56e-08194667e90f6717e3421f8978d1fc1b2f30dcf69f6fcce7
ToppCell3'-Distal_airway-Epithelial-Epithelial_transtional-secretory-tracheobronchial_goblet_cell-Goblet_(subsegmental)|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CYP2F1 CST1 TMED2 STRA6 TMBIM6 SDK1 C16orf89

1.62e-08195667576142b4e75457c0973051bccc4163bd624496af
ToppCell3'-Distal_airway-Epithelial-Epithelial_transtional-secretory-tracheobronchial_goblet_cell|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CYP2F1 CST1 TMED2 STRA6 TMBIM6 SDK1 C16orf89

1.62e-081956678f151066ad3ebd9661ea0b733f03c2ce1518f9ad
ToppCellcellseq2-Epithelial-Epithelial_Glandular-Serous|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

PRR4 PRB1 PRB3 PRB4 PDZK1IP1 PRB2 TMED2

1.74e-08197667d3539607d5477f5dfd85f1fa99b74677c0fa8937
ToppCellcellseq2-Epithelial-Epithelial_Glandular-Serous-Serous|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

PRR4 PRB1 PRB3 PRB4 PDZK1IP1 PRB2 TMED2

1.74e-0819766740bd7c314ff5254d87737822078e7b9eaf23edf3
ToppCellcellseq-Epithelial-Epithelial_Glandular-Serous|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

PRR4 PRB1 PRB3 PRB4 PDZK1IP1 PRB2

3.20e-07184666f0cbb5b76e092be4188a9804ef5cf7a83cd7644f
ToppCellcellseq-Epithelial-Epithelial_Glandular-Serous-Serous|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

PRR4 PRB1 PRB3 PRB4 PDZK1IP1 PRB2

3.20e-071846665433ba7bbab553ff668619822d1a9208e15cd59f
ToppCell3'-Airway_Nasal-Epithelial-Epithelial_transtional-secretory-SMG_serous_secreting_cell-SMG_serous_(nasal)|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

PRR4 PRB1 PRB3 PDZK1IP1 PRB2 TMED2

3.86e-07190666e3a07dcffb75375693738bef1668353f4cdba5d7
ToppCell3'-Airway_Nasal-Epithelial-Epithelial_transtional-secretory-SMG_serous_secreting_cell|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

PRR4 PRB1 PRB3 PDZK1IP1 PRB2 TMED2

3.86e-07190666f6f8451eef5a387b0a1fd2e90ab965928ea2ea82
ToppCell3'-Broncho-tracheal_SMG-Epithelial-Epithelial_transtional-secretory-SMG_tracheobronchial_serous_cell-SMG_serous_(bronchial)-SMG_serous_(bronchial)_L.0.6.1.2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

PRR4 PRB1 PRB3 PRB4 PDZK1IP1 PRB2

3.98e-0719166613460059a0c1ed9f476cef28b8ad4c06349056c6
ToppCell3'-Broncho-tracheal_SMG-Epithelial-Epithelial_transtional-secretory-SMG_tracheobronchial_serous_cell-SMG_serous_(bronchial)-SMG_serous_(bronchial)_L.0.6.1.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

PRR4 PRB1 PRB3 PRB4 PDZK1IP1 PRB2

4.10e-0719266648b69d6f46e583378186d2993a202f9584688bfa
ToppCell3'-Broncho-tracheal_SMG-Epithelial|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

PRR4 PRB1 PRB3 PRB4 PDZK1IP1 PRB2

4.36e-07194666f1d057c4bf57e75ad5a821e5f3de335dbff69062
ToppCell3'-Broncho-tracheal_SMG|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

PRR4 PRB1 PRB3 PRB4 PDZK1IP1 PRB2

4.36e-0719466642558822d7e260e7d8cf2539f1f7426e5774edfb
ToppCell3'-Broncho-tracheal_SMG-Epithelial-Epithelial_transtional-secretory|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

PRR4 PRB1 PRB3 PRB4 PDZK1IP1 PRB2

4.36e-071946660d97dee07846416c77a861994912a9207f29ceb3
ToppCell3'-Broncho-tracheal_SMG-Epithelial-Epithelial_transtional-secretory-SMG_tracheobronchial_serous_cell-SMG_serous_(bronchial)-SMG_serous_(bronchial)_L.0.6.1.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

PRR4 PRB3 PRB4 PDZK1IP1 B2M TMED2

4.36e-07194666a8238f312a973cadf6eb29c1e02ba898c0a20412
ToppCell3'-Distal_airway-Epithelial-Epithelial_transtional-secretory-tracheobronchial_goblet_cell-Goblet_(subsegmental)-Goblet_(subsegmental)_L.0.4.3.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CYP2F1 TMED2 STRA6 TMBIM6 SDK1 C16orf89

4.49e-071956662a9a36df1dbc4eac77a8ddbe939ec8a8d6c41464
ToppCellParenchymal-10x5prime-Stromal-Fibroblastic-Fibro_immune_recruiting|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

LRRC24 SPINK9 TMEM119 CCL21 SDK1 KCNK4

4.63e-07196666614a07334707eafe238d5cb7b080a3ca796a1920
ToppCellcellseq2|World / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

PRR4 PRB1 PRB3 PRB4 PDZK1IP1 PRB2

4.63e-07196666d9e1b8386817a668eca90288b6d0e20be4138bf8
ToppCellBronchial-10x5prime-Epithelial-Epi_submucosal-gland-SMG_Serous|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

PRR4 PRB1 PRB3 PRB4 PDZK1IP1 PRB2

4.77e-0719766692a66e3b5ddc3d55527c31e0d9cff15c2203ecfc
ToppCellBronchial-10x5prime-Epithelial-Epi_submucosal-gland|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

PRR4 PRB1 PRB3 PRB4 PDZK1IP1 PRB2

4.77e-07197666e2c820c4e4a6cd01ceb020473286e3f5d4e3718e
ToppCellTracheal-10x5prime-Epithelial-Epi_submucosal-gland-SMG_Serous|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

PRR4 PRB1 PRB3 PRB4 PDZK1IP1 PRB2

5.21e-07200666e9908b6cba21a59023cf8d0f98fbd1d1f7de6b44
ToppCellTracheal-10x5prime-Epithelial-Epi_submucosal-gland|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

PRR4 DEFB1 PRB1 PRB3 PRB4 PDZK1IP1

5.21e-07200666a3e044468de437948b63c517e0a4773cc247c906
ToppCellTracheal-10x3prime_v2-Epithelial-Epi_airway_secretory-Secretory_Goblet|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

DEFB1 CYP2F1 PDZK1IP1 CCL20 STRA6 C16orf89

5.21e-07200666133853d0f55c63ebe94dd54151f9f1f90650a0d8
ToppCellfacs-Tongue-nan-24m-Epithelial|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CYP2F1 PDZK1IP1 B2M SERPING1 CCL20

4.94e-0616766573fdf4b81a45ec686d2929eaf641b434f70b7898
ToppCellfacs-Tongue-nan-24m|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CYP2F1 PDZK1IP1 B2M SERPING1 CCL20

4.94e-06167665c4157fb31b44fe7c44be4215dda8ae2d37cf49a8
ToppCellP28-Epithelial-epithelial_progenitor_cell|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

RNF186 CYP2F1 MLC1 PDZK1IP1 CCL20

5.08e-0616866503c95ad3684caec7a6d581006b237cc5fa230685
ToppCellP28-Epithelial-epithelial_progenitor_cell-epithelial_progenitor_cell|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

RNF186 CYP2F1 MLC1 PDZK1IP1 CCL20

5.39e-06170665d0ed3a8a7ad96c05641ec409b0a69c4fb094893c
ToppCellcellseq2-Epithelial-Epithelial_Glandular-Goblet-Goblet|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

CYP2F1 ABCA12 RGPD1 STRA6 C16orf89

5.54e-0617166525c1979e972c959e1ce4c57804f976f53a247ad7
ToppCelldroplet-Lung-nan-18m-Epithelial-Club_Cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DEFB1 SLC7A4 CYP2F1 PDZK1IP1 C16orf89

5.54e-061716653b02dc5609f5bcd055b532bb4631d2a7183804e9
ToppCellcellseq2-Epithelial-Epithelial_Glandular-Goblet|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

CYP2F1 ABCA12 RGPD1 STRA6 C16orf89

5.54e-06171665fe27bf581c75ef33c2848878e51ed16b275a4c8e
ToppCelldroplet-Lung-nan-18m-Epithelial-club_cell_of_bronchiole|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DEFB1 SLC7A4 CYP2F1 PDZK1IP1 C16orf89

5.54e-0617166588309bfb1cf427783c853dfd6709cd5edc9074b9
ToppCellTCGA-Head_and_Esophagus-Solid_Tissue_Normal-Head_and_Neck-Head_and_Neck_normal_tissue-5|TCGA-Head_and_Esophagus / Sample_Type by Project: Shred V9

PRR4 CYP2F1 PRB1 PRB3 PRB4

5.70e-061726656b8a8d3b97c10b9d092307eed3cacbd2745df185
ToppCell(03)_Secretory|World / shred by cell type and Timepoint

CYP2F1 PDZK1IP1 B2M TMBIM6 C16orf89

6.37e-06176665cb7b1945788196ca79007f0768b6576ec885a0e5
ToppCell5'-Adult-Appendix-Hematopoietic-T_cells-CX3CR1+_CD8_Tmem|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

S1PR5 CYP2F1 MLC1 RGPD1 CXCR1

6.37e-061766656b06da40eb97ea2db09f3a769494738b3e5fe3fa
ToppCelldroplet-Heart-HEART_(LV+RV_ONLY)|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADAM15 B2M BTNL9 TMEM140 C16orf89

6.92e-06179665fca111789d7354de7ae4cd38253aa0685c0cb2d2
ToppCelldroplet-Heart-HEART_(LV+RV_ONLY)-30m|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADAM15 B2M BTNL9 TMEM140 C16orf89

6.92e-06179665c3e53a3b8e59f7245d737386a1dd0f9d7aa5fb61
ToppCelldroplet-Heart-HEART_(LV+RV_ONLY)-30m-Endothelial-nan|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADAM15 B2M BTNL9 TMEM140 C16orf89

7.50e-06182665506b63a233baf5e3baf924c13c88ab283b6e894f
ToppCell3'-Distal_airway-Epithelial-Epithelial_transtional-secretory-tracheobronchial_goblet_cell-Goblet_(subsegmental)-Goblet_(subsegmental)_L.0.4.3.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CYP2F1 CST1 STRA6 TMBIM6 C16orf89

7.50e-0618266594e70746e35a3062015d4b83ee545f4f84f47420
ToppCellmoderate-Epithelial-IRC-IFNG_responsive_cell|Epithelial / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

DEFB1 B2M SERPING1 CCL20 TMEM140

7.70e-061836654ba879552e2101a341f3224826d364ac64c72260
ToppCellPND07-28-samps-Epithelial|PND07-28-samps / Age Group, Lineage, Cell class and subclass

RNF186 CYP2F1 MLC1 PDZK1IP1 C16orf89

7.70e-06183665a98f1d71d82ed6cca996f74352ab834fb6e95206
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Degenerative_Proximal_Tubule_Epithelial_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

S1PR5 RNF186 PDZK1IP1 B2M TMBIM6

7.91e-061846652b83c7a808e97abf836f53aa3243543c8f6762fb
ToppCellControl-Epithelial_cells-Tuft-like|Control / group, cell type (main and fine annotations)

CYP2F1 B2M GPR78 TMED2 TMBIM6

8.34e-061866659aaab2e81b7ed6a75ded2c3fb1170590c57b74ba
ToppCelldroplet-Marrow-nan-21m-Lymphocytic-nan|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ERGIC3 MS4A3 OS9 TMEM119 STT3A

8.78e-061886657e27e49ec1eb02fb74c86ec2ccb84751bc778b21
ToppCelldroplet-Heart-HEART_(LV+RV_ONLY)-30m-Endothelial-endothelial_cell_of_coronary_artery|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADAM15 B2M BTNL9 TMEM140 C16orf89

8.78e-061886658a87daf2851d9404df7c36f279db599574b47c69
ToppCelldroplet-Heart-HEART_(LV+RV_ONLY)-30m-Endothelial|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADAM15 B2M BTNL9 TMEM140 C16orf89

8.78e-061886650f426cca2ad7671fed9c6d2aa09f6a8627a518cd
ToppCelldroplet-Marrow-nan-21m-Lymphocytic|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ERGIC3 MS4A3 OS9 TMEM119 STT3A

8.78e-061886654b14c3ad80507245564d5be96d33fd9361f67dd0
ToppCellcritical-Epithelial-IRC-IFNG_responsive_cell|Epithelial / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

DEFB1 B2M SERPING1 CCL20 TMEM140

8.78e-06188665023f6e34c2db8657d25e70a97b7b9d45166c13ad
ToppCelldroplet-Heart-HEART_(LV+RV_ONLY)-30m-Endothelial-coronary_vascular_endothelial_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADAM15 B2M BTNL9 TMEM140 C16orf89

8.78e-06188665aec7485f1a9412bd3a62b70c801cb7f8dcca232d
ToppCellfacs-Trachea-3m-Epithelial|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

DEFB1 RNF186 CYP2F1 PDZK1IP1 C16orf89

9.01e-06189665f8959cc2c14899c8dfeb1b5e51e187537df2f03e
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Degenerative_Fibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

B2M GPR78 TMEM119 DCSTAMP CCL21

9.01e-061896659e1a51997ef9b6999d9b40cf0a55e561e3b4a84c
ToppCelldroplet-Lung-nan-18m-Epithelial|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC7A4 RNF186 CYP2F1 MLC1 PDZK1IP1

9.24e-06190665b057bea6e55cef872290893b6e439bbcdcee2f2e
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Degenerative_Fibroblast-Degenerative_Fibroblast_119|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

B2M SERPING1 TMEM119 DCSTAMP CCL21

9.24e-061906657f6dafd5418764d67f6d5ec2153233b791910e81
ToppCelldroplet-Lung-18m-Epithelial|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SLC7A4 RNF186 CYP2F1 MLC1 PDZK1IP1

9.48e-061916651b59f1cad6c1a6a5938afa9195164918e3ff4e86
ToppCell3'-Parenchyma_lung-Immune_Myeloid-Myeloid_macrophage-alveolar_macrophage-Alveolar_macrophage_CCL3+-Alveolar_macrophage_CCL3+_L.1.0.2.3|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

HEXB B2M SERPING1 CCL20 TMEM140

9.97e-061936652653f83bc0289abdb4270c176ebdc24242600f9a
ToppCellfacs-Lung-18m-Epithelial|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

DEFB1 SLC7A4 RNF186 CYP2F1 MLC1

9.97e-061936658e934f127bc763e905c788beabfa867bd559b682
ToppCellfacs-Trachea-24m-Epithelial|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

DEFB1 RNF186 CYP2F1 PDZK1IP1 C16orf89

9.97e-06193665ec49a83b24371579d4ad46aad91c25115aa226f9
ToppCellproximal-Epithelial-Serous-3|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

PRR4 PRB1 PRB3 PRB4 PRB2

1.05e-0519566506b73abc1f32543f2a51db52dc6424a2a398fe0f
ToppCellproximal-Epithelial-Serous|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

PRR4 PRB1 PRB3 PRB4 PRB2

1.05e-05195665cb62f04f0e45bfb36eed2e7a3fc54d6d390b2ed1
ToppCellproximal-3-Epithelial-Serous|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

PRR4 PRB1 PRB3 PRB4 PRB2

1.05e-0519566524a6a566143b04e37ad002e4c55037a0460ac2ef
ToppCell3'-Distal_airway-Epithelial-Epithelial_transtional-secretory-club_cell-Club_(non-nasal)-Club_(non-nasal)_L.0.4.0.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CYP2F1 CST1 STRA6 SDK1 C16orf89

1.07e-05196665020110cd79453df9546fb20802fe38ecadd9fe74
ToppCellBronchial_Biopsy-Epithelial-Club|Bronchial_Biopsy / Tissue, Lineage and Cell class of Lung Cells from 10X

DEFB1 CYP2F1 B2M STRA6 C16orf89

1.07e-05196665057d150bdf0cad959fd03ec2d1560a96ba03fae9
ToppCellBronchial_Biopsy-Epithelial-Club|Epithelial / Tissue, Lineage and Cell class of Lung Cells from 10X

DEFB1 CYP2F1 B2M STRA6 C16orf89

1.10e-051976653f5dfa892a1f631b96eeb6f4cfc284aee51d1ce6
ToppCellBronchial_Brush-Epithelial-Club|Bronchial_Brush / Tissue, Lineage and Cell class of Lung Cells from 10X

DEFB1 CYP2F1 PDZK1IP1 STRA6 C16orf89

1.13e-0519866561292a2b5aacb6080a679a31b70a211bdec59a3b
ToppCellASK440|World / Donor, Lineage and Cell class of Lung cells from Dropseq

HEXB DEFB1 SERPING1 CCL21 TMBIM6

1.13e-05198665f3ed6efd521c691debae32a803972bed5d069332
ToppCell10x_3'_v3-tissue-resident_(10x_3'_v3)-lymphocytic-T_lymphocytic-CD8-positive,_alpha-beta_T_cell|tissue-resident_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

PRR4 PRB1 PRB3 PRB4 PRB2

1.13e-05198665162881a04a981741a0e26e32e0c3c694282701c6
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

DEFB1 PDZK1IP1 B2M SERPING1 TMBIM6

1.16e-05199665fe7708eeada20f8e2c78ba526e6e3323422ba033
ToppCellBronchial_Brush-Epithelial-Club|Epithelial / Tissue, Lineage and Cell class of Lung Cells from 10X

DEFB1 CYP2F1 PDZK1IP1 STRA6 C16orf89

1.16e-0519966553b87edccc89a3e8a6c5166472f9ef24fcba416c
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Degenerative_Cortical_Thick_Ascending_Limb_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

DEFB1 PDZK1IP1 B2M SERPING1 TMBIM6

1.16e-05199665d7be5c5bb9bc9e32e47224729de9af39082b3fcc
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

DEFB1 PDZK1IP1 B2M SERPING1 TMBIM6

1.16e-051996656c7d279c96eb6bf9d7a482cfa0367b722515b2cd
ToppCellTracheal-10x3prime_v2-Epithelial-Epi_submucosal-gland-SMG_Serous|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

PRR4 PRB1 PRB3 PRB4 PRB2

1.18e-0520066561bae10c8b12196d9cee766897971b81cb897191
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Degenerative_Medullary_Thick_Ascending_Limb_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

DEFB1 B2M SERPING1 TMBIM6 C16orf89

1.18e-0520066587c453bb3fa35fff6417dce1f9b08a335fd1546d
ToppCellTracheal-10x3prime_v2-Epithelial-Epi_airway_secretory|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

DEFB1 CYP2F1 PDZK1IP1 CCL20 C16orf89

1.18e-052006658f811ddd84c037a250d124496b0fbb2e4717011c
ToppCellCOVID-19-kidney-Technical/muscle_(PCT)|COVID-19 / Disease (COVID-19 only), tissue and cell type

ABCA12 LCN9 LRP1B PTPRT

5.42e-05139664a1945b07f177cde40e7eea03a19236ce76165857
ToppCellPBMC_fresh-frozen-Mild-Moderate_convalescent_d36-51-Myeloid-Granulocytic-Neutrophil-Neu_c3-CST7|Mild-Moderate_convalescent_d36-51 / Compartment, severity and other cell annotations on 10x 3' data (130k)

B2M STRA6 TMEM140 CXCR1

6.22e-05144664b638398f559e7fd9d4294d1c830beeb20f905960
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Immune-Myeloid-Granulocytic-Mast_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

MS4A3 MLC1 GPR37 CRLF2

7.47e-05151664f5ae450e3daa10540ca8437d05efe2d86ac70960
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

IL13 PDZK1IP1 CCL20 SDK1

7.86e-05153664499670e716fc85ce76630fc813cec86f8419f2a1
ToppCellPND01-Epithelial-Epithelial_Airway-Neurosecretory-Secretory|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

RNF186 CYP2F1 CCL20 C16orf89

9.35e-05160664b4844a8c7755a2b2868019791d8d224154973445
ToppCellPND01-Epithelial-Epithelial_Airway-Neurosecretory-Secretory-Secretory_mature|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

RNF186 CYP2F1 CCL20 C16orf89

9.35e-0516066401ae730e9d0d05f3277f862f0c09bafb32b89db5
ToppCellPND01-Epithelial-Epithelial_Airway-Neurosecretory|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

RNF186 CYP2F1 CCL20 C16orf89

9.35e-051606646de9e7be1d860d82d503bfbc779e72f072a6efc3
ToppCellPND07-28-samps-Epithelial-Epithelial-non_alveolar-Club_cell|PND07-28-samps / Age Group, Lineage, Cell class and subclass

RNF186 CYP2F1 PDZK1IP1 C16orf89

9.81e-05162664aed15eef32419b8a4e2afdb9776c2bf2802e96f1
ToppCell390C-Lymphocytic-NK_cells-NK_cell_B2|390C / Donor, Lineage, Cell class and subclass (all cells)

S1PR5 B2M CTRL CXCR1

1.00e-04163664036e65de0f8fc391f3e4d299bf4c05ee5c3b5a37
ToppCell367C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_0.5|367C / Donor, Lineage, Cell class and subclass (all cells)

S1PR5 MLC1 B2M CXCR1

1.03e-041646644a834a7908d8aa643a2096c52430dad795898474
ToppCellLAM-Myeloid-Mast|LAM / Condition, Lineage and Cell class

IL13 SLC7A4 MS4A3 CRLF2

1.08e-04166664e0ce973cc2a091b832c67b3b32dc153379daa2ef
ToppCell3'-Child04-06-SmallIntestine-Hematopoietic-T_cells-Th1|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

S1PR5 SLC7A4 CCL20 CTRL

1.10e-041676649c55ec8f70b86d4d3d5c2a6ecd9bff2dafe68c11
ToppCellILEUM-non-inflamed-(4)_Mast|non-inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

IL13 MS4A3 PDZK1IP1 CRLF2

1.10e-04167664de0cb257def6049830af068f8f74829a708b810f
ToppCellILEUM-non-inflamed-(4)_Mast_cells|non-inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

IL13 MS4A3 PDZK1IP1 CRLF2

1.10e-0416766485b39e05eb6e18e06b47e374d808e479ca65173c
ToppCell3'-Distal_airway-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.2.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DOCK3 LRRC24 CYP2F1 SDK1

1.13e-04168664de0b00bc405c898d08a06b2e585fb62c0ab9a66e
ToppCellASK440-Immune-B_cell|Immune / Donor, Lineage and Cell class of Lung cells from Dropseq

CUL4B CYP2F1 ADCY6 TPCN1

1.13e-04168664127559d1a083c68cda9fce143afcc3eec168df17
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Immune-Myeloid-Granulocytic|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

MLC1 GPR37 CRLF2 CXCR1

1.15e-041696642e15a9317da4017757d184f7cc91bd66b072ac51
ToppCellfacs-Tongue-nan-24m-Epithelial-nan|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CYP2F1 PDZK1IP1 B2M SERPING1

1.15e-041696640054f9bfd4d377c7fd94873c1308622051c59a8e
ToppCellsevere_COVID-19-Neutrophil|World / disease group, cell group and cell class (v2)

B2M SERPING1 TMEM140 CXCR1

1.18e-04170664dfc807e0dd66179490a258ecbe8eb439e715799d
ToppCellfacs-Brain_Myeloid-Hippocampus-24m-Myeloid-microglial_cell|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TMEM119 SDK1 CRLF2 TPCN1

1.18e-04170664b4f2c05db2c2591561fd42febc72eed3b5e8f9fb
ToppCelldroplet-Tongue-nan-24m-Epithelial-suprabasal_interpapillary|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CYP2F1 PDZK1IP1 B2M CCL20

1.24e-041726646ece9bb9f31685c918ca4cb7b82cf6ad1cad48af
ToppCellsevere_COVID-19-Neutrophil|severe_COVID-19 / disease group, cell group and cell class (v2)

B2M SERPING1 TMEM140 CXCR1

1.24e-041726648f4bcb9b2bbf8b4333f673d8ad6bb88dfda4792a
Diseasepulmonary fibrosis (is_marker_for)

DEFB1 IL13 CCL21

4.40e-0532633DOID:3770 (is_marker_for)
Diseaseureteral obstruction (biomarker_via_orthology)

GJA5 B2M ADCY6

1.23e-0445633DOID:5199 (biomarker_via_orthology)
Diseaseanxiety disorder, stress-related disorder

SDK1 PTPRT

2.92e-0412632EFO_0006788, EFO_0010098
Diseasechronic obstructive pulmonary disease (is_implicated_in)

DEFB1 IL13 LRP1B

3.36e-0463633DOID:3083 (is_implicated_in)
DiseaseParkinson's disease (is_marker_for)

GPR37 B2M NTSR1

4.03e-0467633DOID:14330 (is_marker_for)
Diseasefacial attractiveness measurement

LRP1B PTPRT

7.49e-0419632EFO_0009892
Diseaseattention deficit hyperactivity disorder (is_implicated_in)

DOCK3 HTR1B

8.32e-0420632DOID:1094 (is_implicated_in)
Diseaselung disease (is_marker_for)

DEFB1 IL13

1.01e-0322632DOID:850 (is_marker_for)
DiseaseSeizures

CUL4B HEXB HTR1B KCNK4

1.23e-03218634C0036572
Diseasepancreatic cancer (is_marker_for)

IL13 ADAM15 CCL20

1.33e-03101633DOID:1793 (is_marker_for)
Diseasepneumonia (is_marker_for)

DEFB1 IL13

1.64e-0328632DOID:552 (is_marker_for)
Diseasevitamin B12 measurement

MS4A3 SDK1

2.14e-0332632EFO_0004620
DiseaseMalignant neoplasm of lung

ERGIC3 SERPING1 SMC2 PTPRT

2.53e-03266634C0242379
Diseaseatopic dermatitis (is_marker_for)

IL13 CCL20

2.55e-0335632DOID:3310 (is_marker_for)
Diseaseparasitemia measurement

HTR1B GPR78

2.85e-0337632EFO_0005528
Diseaseairway imaging measurement

GJA5 ABCA12

3.00e-0338632EFO_0007627
Diseaseankylosing spondylitis, psoriasis, ulcerative colitis, Crohn's disease, sclerosing cholangitis

RNF186 CCL20 CCL21 CXCR1

3.67e-03295634EFO_0000384, EFO_0000676, EFO_0000729, EFO_0003898, EFO_0004268
Diseaseobesity (biomarker_via_orthology)

DEFB1 GJA5 HTR1B

3.87e-03147633DOID:9970 (biomarker_via_orthology)

Protein segments in the cluster

PeptideGeneStartEntry
MSRSVALAVLALLSL

B2M

1

P61769
MLLLSLTLSLVLLGS

CTRL

1

P40313
LLVMLLALITLATTL

HTR1B

51

P28222
LTSSLVFLMHLLLLQ

BTNL9

16

Q6UXG8
MAQSLALSLLILVLA

CCL21

1

O00585
MASLGLLLLLLLTAL

C16orf89

1

Q6UX73
TGLLLSLLVLLVLVM

ADAM15

696

Q13444
SLTLLMAVLVLLTAV

ADCY6

151

O43306
ISSLIDILVALSILM

ABCA12

1981

Q86UK0
LLLFTLCLLLSEMAS

DEFB1

6

P60022
ILLLLLTSVMFLLSL

SLC7A4

511

O43246
MDSISTAILLLLLAL

CYP2F1

1

P24903
MSEFLLALLTLSGLL

LRP1B

1

Q9NZR2
GSLALSDLLTLLLAM

NTSR1

106

P30989
IVLLLALTLATMFSI

SPINK9

6

Q5DT21
MRSTTLLALLALVLL

KCNK4

1

Q9NYG8
MALLLLSLGLSLIAA

LCN9

1

Q8WX39
LFLSMLALIDLGLSL

OR51G2

66

Q8NGK0
MSALSLLILGLLTAV

PDZK1IP1

1

Q13113
TIVSGLLMLLLFLSE

ERGIC3

31

Q9Y282
SVILLILVMLGLLSS

DCSTAMP

381

Q9H295
ALGLMALLLTTVIAL

IL13

11

P35225
IALLALTALLLVAMI

LRRC24

411

Q50LG9
TSLVLTAMLILSLRL

OR13H1

151

Q8NG92
SSLAILLMVSLLLLS

CRLF2

236

Q9HC73
SLLELMVILLAVVTL

OR6C4

191

Q8NGE1
LLVMVLAVALLSNAL

GPR78

11

Q96P69
LLLATLAFSDIMLSL

GPR45

71

Q9Y5Y3
MASLAALALSLLLRL

PTPRT

1

O14522
LRSIILLLMGSDILS

ESPL1

946

Q14674
MSRLLLLLLLKVSAS

GPR37

11

O15354
SLLDVLLQTLLTIMS

DOCK3

906

Q8IZD9
LLSLMTLTLFSPDLL

MT-CYB

236

P00156
MLAVAALSLLLSLAE

GJA5

211

P36382
LLSLLGNSLVMLVIL

CXCR1

51

P25024
ILMSALSLLLLSSLG

TMBIM6

146

P55061
MASRLTLLTLLLLLL

SERPING1

1

P05155
SLRSLTAQLLVLLMS

MARF1

1411

Q9Y4F3
MAQYLSTLLLLLATL

CST1

1

P01037
ALLLATLLAAMLALL

HEXB

16

P07686
TLLAAMLALLTQVAL

HEXB

21

P07686
LLVMALSSLIVILLV

SDK1

2011

Q7Z5N4
MFLLLGSLTLSDLLA

S1PR5

71

Q9H228
SLLRSLLSMLSDLQI

CUL4B

366

Q13620
MLLILLSVALLAFSS

PRH1;

1

P02810
MLLILLSVALLALSS

PRB2

1

P02812
MLLILLSVALLALSS

PRB4

1

P10163
LLLAYANLMLLTLST

RGPD1

226

P0DJD0
ALMSNLLIITLITLD

OR14A2

36

Q96R54
TMALCLLTLVLSLLP

MUC17

6

Q685J3
VSLLLTLSILSIMAG

MT-ND2

151

P03891
NGMVSLLLILTLLEL

MS4A3

171

Q96HJ5
VLTFIIALALLMSTL

RNF186

181

Q9NXI6
QLLLSLTMLLLAFVT

MOSPD2

496

Q8NHP6
TLVNLAGLLVSLLML

RUSF1

236

Q96GQ5
SAQALLILLLIAMAV

TMEM140

156

Q9NV12
TLLKLLILSMAAVLS

STT3A

16

P46977
MAAETLLSSLLGLLL

OS9

1

Q13438
LASLSILVLLLLAML

STRA6

56

Q9BX79
SLLLAALMSVLLLHL

CCL20

6

P78556
MLLILLSVALLALSS

PRB3

1

Q04118
MLLILLSVALLALSS

PRB1

1

P04280
LMVMSSLLLIIILAL

MT-ND3

86

P03897
LLLNLTLSDIMVSLA

TEX10

431

Q9NXF1
SLVALSLILSMLLFK

SMC2

1091

O95347
MLLVLLSVVLLALSS

PRR4

1

Q16378
MLLFSVLLLLSLVTG

PRSS55

1

Q6UWB4
MVTLAELLVLLAALL

TMED2

1

Q15363
MELATALLLLLLSLC

TPCN1

111

Q9ULQ1
MVSAAAPSLLILLLL

TMEM119

1

Q4V9L6
LILLLLLELLMAATV

MLC1

146

Q15049