Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionp53 binding

CDKN2AIP TRIM24 SIRT1 TP53BP1

9.62e-0577624GO:0002039
GeneOntologyMolecularFunctionmitogen-activated protein kinase binding

TNIP1 SIRT1 MAP3K1

1.74e-0435623GO:0051019
GeneOntologyMolecularFunctionmodification-dependent protein binding

UBAC1 TNIP1 TRIM24 SIRT1 TP53BP1

4.47e-04206625GO:0140030
DomainGroES-like

FASN TRIM55

2.68e-0324602IPR011032
Domainzf-C4

NR2F6 RORA

9.59e-0346602PF00105
DomainZnf_hrmn_rcpt

NR2F6 RORA

9.59e-0346602IPR001628
DomainNuclear_hrmn_rcpt

NR2F6 RORA

9.59e-0346602IPR001723
DomainNUCLEAR_REC_DBD_2

NR2F6 RORA

9.59e-0346602PS51030
DomainNUCLEAR_REC_DBD_1

NR2F6 RORA

9.59e-0346602PS00031
DomainZnF_C4

NR2F6 RORA

9.59e-0346602SM00399
Domain-

NR2F6 RORA

1.00e-02476021.10.565.10
DomainHOLI

NR2F6 RORA

1.04e-0248602SM00430
DomainNucl_hrmn_rcpt_lig-bd

NR2F6 RORA

1.04e-0248602IPR000536
DomainHormone_recep

NR2F6 RORA

1.04e-0248602PF00104
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

NR2F6 FASN KMT2D TKFC KIF26A TMCC2 ZNF516 KBTBD11 IRS1 ZC3H7B TIMM22 CRAMP1

4.98e-071105621235748872
Pubmed

Neuron-specific protein network mapping of autism risk genes identifies shared biological mechanisms and disease-relevant pathologies.

SHISA9 IQSEC3 UBE2O TXNDC5 CAMKV BASP1 TMCC2 CBARP EIF3B PCDH8 MARCKS TP53BP1

6.85e-071139621236417873
Pubmed

Proteomic analyses reveal distinct chromatin-associated and soluble transcription factor complexes.

CRACD NR2F6 FASN KMT2D TXNDC5 TNIP1 TAF10 TRIM24 CUX1 TP53BP1

2.64e-06857621025609649
Pubmed

Qualitative and quantitative analyses of protein phosphorylation in naive and stimulated mouse synaptosomal preparations.

IQSEC3 SNAP91 BASP1 PRRT3 KBTBD11 CBARP MARCKS

2.85e-0634762717114649
Pubmed

Intratumoral heterogeneity for inactivating frameshift mutation of CUX1 and SIRT1 genes in gastric and colorectal cancers.

SIRT1 CUX1

3.13e-06262229363918
Pubmed

Nuclear actin interactome analysis links actin to KAT14 histone acetyl transferase and mRNA splicing.

CRACD FASN UBE2O BASP1 BOD1L1 EIF3B TAF10 TP53BP1

3.23e-0650662830890647
Pubmed

Phosphoproteomic analysis of the developing mouse brain.

SNAP91 CAMKV TELO2 TMCC2 EIF3B MARCKS

5.20e-0624662615345747
Pubmed

Human transcription factor protein interaction networks.

UBE2O KMT2D BASP1 ATF7IP ZNF516 TNIP1 EIF3B TAF10 TRIM24 SIRT1 CUX1 TP53BP1

7.11e-061429621235140242
Pubmed

Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.

IQSEC3 UBE2O SNAP91 CAMKV BASP1 ATF7IP ZNF516 PCDH8 CUX1 TP53BP1

7.38e-06963621028671696
Pubmed

MEK kinase 1 interacts with focal adhesion kinase and regulates insulin receptor substrate-1 expression.

IRS1 MAP3K1

9.37e-06362212458213
Pubmed

1,25(OH)2-vitamin D3 upregulates glucose uptake mediated by SIRT1/IRS1/GLUT4 signaling cascade in C2C12 myotubes.

IRS1 SIRT1

9.37e-06362229188534
Pubmed

KAP1 Deacetylation by SIRT1 Promotes Non-Homologous End-Joining Repair.

SIRT1 TP53BP1

9.37e-06362225905708
Pubmed

Genetic Susceptibility to Posttraumatic Stress Disorder: Analyses of the Oxytocin Receptor, Retinoic Acid Receptor-Related Orphan Receptor A and Cannabinoid Receptor 1 Genes.

OXTR RORA

9.37e-06362231291229
Pubmed

The motility-associated proteins GAP-43, MARCKS, and CAP-23 share unique targeting and surface activity-inducing properties.

BASP1 MARCKS

9.37e-0636229344590
Pubmed

GAP43, MARCKS, and CAP23 modulate PI(4,5)P(2) at plasmalemmal rafts, and regulate cell cortex actin dynamics through a common mechanism.

BASP1 MARCKS

9.37e-06362210871285
Pubmed

The direct involvement of SirT1 in insulin-induced insulin receptor substrate-2 tyrosine phosphorylation.

IRS1 SIRT1

9.37e-06362217901049
Pubmed

Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.

FASN KMT2D ATF7IP ZNF516 TNIP1 TRIM24 CUX1

9.59e-0641862734709266
Pubmed

Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.

UBE2O TXNDC5 TELO2 BASP1 TNIP1 CBARP GNAS TRIM24 MARCKS SIRT1 CUX1 TP53BP1

1.06e-051487621233957083
Pubmed

Phosphoinositide 3-kinase as a novel functional target for the regulation of the insulin signaling pathway by SIRT1.

IRS1 SIRT1

1.87e-05462221241768
Pubmed

PRISMA and BioID disclose a motifs-based interactome of the intrinsically disordered transcription factor C/EBPα.

FASN KMT2D TXNDC5 CDKN2AIP ZNF516 TAF10 TRIM24 SIRT1 CUX1 TP53BP1

2.38e-051103621034189442
Pubmed

Charting the landscape of tandem BRCT domain-mediated protein interactions.

FASN UBE2O CDKN2AIP EIF3B SIRT1 CUX1 MAP3K1 TP53BP1

2.46e-0567062822990118
Pubmed

Genome-wide contribution of genotype by environment interaction to variation of diabetes-related traits.

SLC22A23 NRG3 MAP3K1

2.83e-053362324204828
Pubmed

Targeting Neurons with Functional Oxytocin Receptors: A Novel Set of Simple Knock-In Mouse Lines for Oxytocin Receptor Visualization and Manipulation.

OXTR CUX1

3.12e-05562235082173
Pubmed

Feedback regulation of hepatic gluconeogenesis through modulation of SHP/Nr0b2 gene expression by Sirt1 and FoxO1.

IRS1 SIRT1

3.12e-05562221081708
Pubmed

BPA modulates the WDR5/TET2 complex to regulate ERβ expression in eutopic endometrium and drives the development of endometriosis.

FASN UBE2O KMT2D TKFC TXNDC5 CDKN2AIP EIF3B TAF10

3.75e-0571162833022573
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

UBE2O TELO2 KIF26A ZNF516 KBTBD11 ZC3H7B CRAMP1

4.32e-0552962714621295
Pubmed

p53 regulates cell cycle and microRNAs to promote differentiation of human embryonic stem cells.

TRIM24 SIRT1

4.67e-05662222389628
Pubmed

The N-terminal part of TIF1, a putative mediator of the ligand-dependent activation function (AF-2) of nuclear receptors, is fused to B-raf in the oncogenic protein T18.

TAF10 TRIM24

4.67e-0566227744009
Pubmed

SRCAP complex promotes lung cancer progression by reprograming the oncogenic transcription of Hippo-YAP/TAZ signaling pathway.

FASN UBE2O KMT2D TNIP1 BOD1L1 CUX1 TP53BP1

5.46e-0554962738280479
Pubmed

Differential ligand-dependent interactions between the AF-2 activating domain of nuclear receptors and the putative transcriptional intermediary factors mSUG1 and TIF1.

TAF10 TRIM24

6.53e-0576228598193
Pubmed

Large-scale characterization of HeLa cell nuclear phosphoproteins.

NR2F6 TBC1D10B FASN KMT2D ZNF516 EIF3B SIRT1 TP53BP1

6.80e-0577462815302935
Pubmed

HAPSTR1 localizes HUWE1 to the nucleus to limit stress signaling pathways.

TBC1D10B FASN UBE2O TELO2 EIF3B GNAS SIRT1

6.98e-0557162737167062
Pubmed

DNA damage response in microcephaly development of MCPH1 mouse model.

CUX1 TP53BP1

8.69e-05862223683352
Pubmed

Identification and characterisation of spontaneous mutations causing deafness from a targeted knockout programme.

KMT2D TBX1

1.12e-04962235296311
Pubmed

Extracellular secretagogin is internalized into the cells through endocytosis.

FASN IRS1

1.12e-04962234967502
Pubmed

Spatiotemporal Gradient of Cortical Neuron Death Contributes to Microcephaly in Knock-In Mouse Model of Ligase 4 Syndrome.

CUX1 TP53BP1

1.12e-04962231541646
Pubmed

Suppression of DNA Double-Strand Break Formation by DNA Polymerase β in Active DNA Demethylation Is Required for Development of Hippocampal Pyramidal Neurons.

CUX1 TP53BP1

1.70e-041162233087478
Pubmed

Telencephalic embryonic subtractive sequences: a unique collection of neurodevelopmental genes.

BASP1 ATF7IP SIRT1 TP53BP1

2.20e-0416562416107646
Pubmed

Pro-prion, as a membrane adaptor protein for E3 ligase c-Cbl, facilitates the ubiquitination of IGF-1R, promoting melanoma metastasis.

XKR7 UBE2O TXNDC5 ZNF516 FGD5 TAF10 TRIM24

2.22e-0468962736543142
Pubmed

Thalamocortical axons control the cytoarchitecture of neocortical layers by area-specific supply of VGF.

RORA CUX1

2.41e-041362235289744
Pubmed

N-Terminal Acetyltransferase Naa40p Whereabouts Put into N-Terminal Proteoform Perspective.

CRACD FASN UBE2O ATF7IP CDKN2AIP BOD1L1 MARCKS TP53BP1

2.46e-0493462833916271
Pubmed

Arid5a regulates naive CD4+ T cell fate through selective stabilization of Stat3 mRNA.

RORA TBX1

2.81e-041462227022145
Pubmed

The BRCT-domain containing protein PTIP links PAX2 to a histone H3, lysine 4 methyltransferase complex.

KMT2D TP53BP1

3.23e-041562217925232
Pubmed

Tip60/KAT5 Histone Acetyltransferase Is Required for Maintenance and Neurogenesis of Embryonic Neural Stem Cells.

CUX1 TP53BP1

3.69e-041662236768434
Pubmed

Sex-stratified genome-wide association studies including 270,000 individuals show sexual dimorphism in genetic loci for anthropometric traits.

IRS1 MAP3K1

4.18e-041762223754948
Pubmed

The MEKK1 PHD ubiquitinates TAB1 to activate MAPKs in response to cytokines.

UBAC1 TNIP1 MAP3K1

4.32e-048262325260751
Pubmed

Identification of the SOX2 Interactome by BioID Reveals EP300 as a Mediator of SOX2-dependent Squamous Differentiation and Lung Squamous Cell Carcinoma Growth.

KMT2D TRIM24 CUX1

4.48e-048362328794006
Pubmed

Defining the proximal interaction networks of Arf GTPases reveals a mechanism for the regulation of PLD1 and PI4KB.

TENT4B BASP1 ATF7IP KBTBD11 CBARP MARCKS CUX1

4.58e-0477762735844135
Pubmed

Genome-wide association of mood-incongruent psychotic bipolar disorder.

SNAP91 BASP1

4.70e-041862223092984
Pubmed

PTIP associates with MLL3- and MLL4-containing histone H3 lysine 4 methyltransferase complex.

KMT2D TP53BP1

4.70e-041862217500065
Pubmed

BCL6 controls neurogenesis through Sirt1-dependent epigenetic repression of selective Notch targets.

SIRT1 CUX1

5.24e-041962223160044
Pubmed

Diminished dosage of 22q11 genes disrupts neurogenesis and cortical development in a mouse model of 22q11 deletion/DiGeorge syndrome.

CUX1 TBX1

5.24e-041962219805316
Pubmed

Lunatic fringe potentiates Notch signaling in the developing brain.

RORA CUX1

5.24e-041962220510365
Pubmed

A cohesin-RAD21 interactome.

FASN UBE2O CDKN2AIP EIF3B

5.29e-0420862422145905
Pubmed

Genome-wide CRISPR screens identify novel regulators of wild-type and mutant p53 stability.

ATF7IP ZNF516 TNIP1 GNAS SIRT1 TP53BP1

6.27e-0458862638580884
Pubmed

Structural basis for activity regulation of MLL family methyltransferases.

KMT2D BOD1L1

7.06e-042262226886794
Pubmed

A signature motif mediating selective interactions of BCL11A with the NR2E/F subfamily of orphan nuclear receptors.

NR2F6 RORA

7.06e-042262223975195
Pubmed

Identification and functional characterization of transcriptional activators in human cells.

KMT2D ATF7IP ZNF516 TRIM24 CUX1

7.25e-0439862535016035
Pubmed

The treasury of the commons: making use of public gene expression resources to better characterize the molecular diversity of inhibitory interneurons in the cerebellar cortex.

IQSEC3 RORA CUX1

7.27e-049862319554387
Pubmed

Cortical Development Requires Mesodermal Expression of Tbx1, a Gene Haploinsufficient in 22q11.2 Deletion Syndrome.

CUX1 TBX1

7.72e-042362227005988
Pubmed

Identification of new ciliary signaling pathways in the brain and insights into neurological disorders.

CAMKV BASP1 CBARP PCDH8 MARCKS

7.84e-0440562538187761
Pubmed

CHFR regulates chemoresistance in triple-negative breast cancer through destabilizing ZEB1.

UBE2O ZNF516 SIRT1

7.94e-0410162334462429
Pubmed

Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.

FASN UBE2O TENT4B TXNDC5 BOD1L1 FGD5 EIF3B GNAS MARCKS

9.09e-04142562930948266
Pubmed

Direct binding of CoREST1 to SUMO-2/3 contributes to gene-specific repression by the LSD1/CoREST1/HDAC complex.

ATF7IP CUX1 TP53BP1

9.13e-0410662319394292
Pubmed

TNF-α inhibits glucocorticoid receptor-induced gene expression by reshaping the GR nuclear cofactor profile.

KMT2D TXNDC5 ZNF516 FGD5 TRIM24 CUX1

9.58e-0463862631182584
Pubmed

A high-throughput approach for measuring temporal changes in the interactome.

FASN UBE2O TKFC TXNDC5 TELO2 BASP1 EIF3B MARCKS SIRT1

1.05e-03145562922863883
Pubmed

SETD1A Methyltransferase Is Physically and Functionally Linked to the DNA Damage Repair Protein RAD18.

TBC1D10B KMT2D BOD1L1 TP53BP1

1.06e-0325162431076518
Pubmed

Bulk and mosaic deletions of Egfr reveal regionally defined gliogenesis in the developing mouse forebrain.

NRG3 CUX1

1.07e-032762236915679
Pubmed

ATDC (Ataxia Telangiectasia Group D Complementing) Promotes Radioresistance through an Interaction with the RNF8 Ubiquitin Ligase.

BASP1 MARCKS

1.15e-032862226381412
Pubmed

Quantitative dissection and stoichiometry determination of the human SET1/MLL histone methyltransferase complexes.

KMT2D BOD1L1 TP53BP1

1.28e-0311962323508102
Pubmed

Histone methyltransferase DOT1L coordinates AR and MYC stability in prostate cancer.

KMT2D TKFC TELO2 GNAS

1.28e-0326462432814769
Pubmed

Systematic proteomics of endogenous human cohesin reveals an interaction with diverse splicing factors and RNA-binding proteins required for mitotic progression.

FASN RORA BOD1L1 EIF3B

1.43e-0327262431010829
Pubmed

Mutations of the Transcriptional Corepressor ZMYM2 Cause Syndromic Urinary Tract Malformations.

ATF7IP ZNF516 TRIM24

1.47e-0312562332891193
Pubmed

The Nse5/6-like SIMC1-SLF2 complex localizes SMC5/6 to viral replication centers.

SNAP91 ATF7IP CDKN2AIP BOD1L1 TRIM24 CUX1 TP53BP1

1.51e-0395462736373674
Pubmed

EVI1 oncoprotein interacts with a large and complex network of proteins and integrates signals through protein phosphorylation.

UBAC1 ZNF516 TP53BP1

1.57e-0312862323858473
Pubmed

FGF11 induced by hypoxia interacts with HIF-1α and enhances its stability.

FASN UBE2O SIRT1

1.57e-0312862328027390
Pubmed

Synaptic GAP and GEF Complexes Cluster Proteins Essential for GTP Signaling.

IQSEC3 BASP1 KBTBD11 GNAS

1.61e-0328162428706196
Pubmed

PINK1 Content in Mitochondria is Regulated by ER-Associated Degradation.

FASN UBE2O EIF3B MARCKS CUX1

1.62e-0347762531300519
Pubmed

VCP phosphorylation-dependent interaction partners prevent apoptosis in Helicobacter pylori-infected gastric epithelial cells.

TBC1D10B TELO2 CDKN2AIP TP53BP1

1.76e-0328862423383273
InteractionACTC1 interactions

CRACD FASN UBE2O BASP1 TMCC2 TNIP1 BOD1L1 FGD5 EIF3B TAF10 TP53BP1

6.50e-066946111int:ACTC1
InteractionSUMO2 interactions

FASN BASP1 ATF7IP TNIP1 BOD1L1 TRIM24 MARCKS SIRT1 CUX1 TP53BP1

1.02e-055916110int:SUMO2
InteractionMYOD1 interactions

UBE2O KMT2D RORA TRIM24 SIRT1 CUX1

2.63e-05194616int:MYOD1
InteractionPRKCZ interactions

SLC35G1 FASN UBE2O TXNDC5 BASP1 IRS1 EIF3B MARCKS

3.25e-05412618int:PRKCZ
InteractionFLNB interactions

FASN BASP1 ATF7IP TRIM55 TNIP1 FGD5 MAP3K1

3.60e-05304617int:FLNB
Cytoband10q23.33

SLC35G1 TBC1D12

4.46e-042362210q23.33
CytobandEnsembl 112 genes in cytogenetic band chr3p25

OXTR PRRT3 FGD5

1.23e-03155623chr3p25
CytobandEnsembl 112 genes in cytogenetic band chr10q23

SLC35G1 TBC1D12 NRG3

2.37e-03195623chr10q23
CoexpressionGSE40666_WT_VS_STAT1_KO_CD8_TCELL_DN

NR2F6 RORA FGD5 EIF3B ANKRD63 ZC3H7B

7.89e-06200626M9207
CoexpressionPEREZ_TP53_TARGETS

SHISA9 CRACD KIF26A SLC22A23 NRK TMCC2 PRRT3 RORA PRR22 FGD5 GNAS CRAMP1

2.09e-0512016212M4391
ToppCellCOVID|World / Condition, Cell_class and T cell subcluster

ARHGAP22 BASP1 UBAC1 BOD1L1 GNAS TAF10 MARCKS

1.23e-0820062704a932fe2431e7886120c219ce666f90d3030a1c
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_1-Inh_L1_VIP_PRSS8|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

CRACD ADRA1D KIF26A TRIM55 FGD5 PCDH8

2.26e-071856264c42bd3cd72f91f4d4ebb849069a03761a2cd662
ToppCellILEUM-non-inflamed-(7)_Endothelial_cell-(7)_Lymphatics|(7)_Endothelial_cell / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

KBTBD11 EIF3B GNAS MARCKS TBX1 MAP3K1

2.65e-071906269ce301841ce9486701fa28eb2a9929e35d476878
ToppCell3'-GW_trimst-2-SmallIntestine-Endothelial-lymphatic_endothelial-LEC3_(ADGRG3+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TXNDC5 MAGED4 KIF26A SLC22A23 TBX1

4.55e-0617562543be63976da5ad0764d24d90919a77ce46068f52
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_PAX6-Inh_L1_PAX6_GRIP2|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

CRACD ADRA1D TRIM55 FGD5 PCDH8

4.55e-061756250c648e7f67ffbe3b476a2ca77d246554f8cd1882
ToppCell3'_v3-Lung-Myeloid_Dendritic-migDC|Lung / Manually curated celltypes from each tissue

ARHGAP22 BASP1 SLC22A23 TMCC2 MARCKS

5.50e-06182625cd6e3a9f4eb4fe73b28da61d1d35c64fd9ffa892
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_1-Inh_L1-6_VIP_RCN1|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

CRACD KIF26A FGD5 PCDH8 MAP3K1

5.96e-06185625538db481c82b02e5d3b8e03b166f754cc936901e
ToppCellnormal_Lung-Myeloid_cells-Activated_DCs|normal_Lung / Location, Cell class and cell subclass

ARHGAP22 CRACD BASP1 SLC22A23 MARCKS

6.12e-061866250987c9a39503eb6c75a2bf4db98b2b2fd46956fb
ToppCellnormal_Lung-Myeloid_cells-Activated_DCs|Myeloid_cells / Location, Cell class and cell subclass

ARHGAP22 CRACD BASP1 SLC22A23 MARCKS

6.12e-0618662500ad1239b952119b3fd2e6af8f034cba3488f9c1
ToppCell390C-Endothelial_cells-Endothelial-F_(Lymphatics)|390C / Donor, Lineage, Cell class and subclass (all cells)

IQSEC3 KBTBD11 FGD5 MARCKS TBX1

6.44e-06188625aa69e3f44d506f5ef358a3374ac5160d847c858f
ToppCell390C-Endothelial_cells-Endothelial-F_(Lymphatics)-|390C / Donor, Lineage, Cell class and subclass (all cells)

IQSEC3 KBTBD11 FGD5 MARCKS TBX1

6.44e-061886251f40b959777d18ad88d239df8cca304f062ba04c
ToppCellBrain_organoid-organoid_Paulsen_bioRxiv-3.5_mon-Neuronal-Immature_INs|3.5_mon / Sample Type, Dataset, Time_group, and Cell type.

CRACD BASP1 GNAS MARCKS MAP3K1

6.78e-06190625842760bfe0a52e67bad800efa7d99448a4a23ebb
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_2|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

CRACD FGD5 IRS1 GNAS PCDH8

7.14e-06192625025fac36b862f9ca7f96fb4a1946c44ba7cbc382
ToppCell367C-Myeloid-Dendritic-cDC_activated|Dendritic / Donor, Lineage, Cell class and subclass (all cells)

ARHGAP22 SLC22A23 TMCC2 ZC3H7B MARCKS

7.14e-06192625e44e37e5aeba8628556020d05e1606b28e2faa4f
ToppCellILEUM-inflamed-(7)_Endothelial_cell-(7)_Lymphatics|(7)_Endothelial_cell / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

KBTBD11 GNAS MARCKS TBX1 MAP3K1

7.14e-06192625d43caf42ec744e895137f31ef65a990e250669d2
ToppCellfacs-Brain_Non-Myeloid-Cortex-3m-Neuronal-neuron|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IQSEC3 SNAP91 CAMKV CBARP NRG3

7.32e-06193625461919ab422bc9d1fcff7a3a4757c75239041d7e
ToppCellfacs-Brain_Non-Myeloid-Cortex-3m-Neuronal-nan|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IQSEC3 SNAP91 CAMKV CBARP NRG3

7.32e-061936250dd810ad900d3e586551622b2c1de39d76fd6a7f
ToppCellCOPD-Endothelial-Lymphatic|Endothelial / Disease state, Lineage and Cell class

SLC22A23 KBTBD11 RORA MARCKS TBX1

7.69e-06195625e91ce548ae7224661ee5d2f2639794a5f69798ee
ToppCelltumor_Lung-Endothelial_cells-Lymphatic_ECs|Endothelial_cells / Location, Cell class and cell subclass

TXNDC5 SLC22A23 KBTBD11 MARCKS TBX1

8.08e-06197625a05237ee6d31d9eab491dd7007859d6285cf1424
ToppCellLPS-antiTNF-Hematopoietic_Mast-Mast_cells-T-cells|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

IQSEC3 TBC1D10B RORA PCDH8

5.27e-051476241ecd7c084e73eb6fae1ab1f9aae17115d3d62cbd
ToppCellLPS-antiTNF-Hematopoietic_Mast-Mast_cells|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

IQSEC3 TBC1D10B RORA PCDH8

5.55e-0514962459aa1f2a5cbeba64c4529fb05f544db17fd8b188
ToppCellLPS-antiTNF-Hematopoietic_Mast|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

IQSEC3 TBC1D10B RORA PCDH8

5.55e-051496241527cdd98a2734cbf8ce4c6170557280b71c55cb
ToppCellCOVID-19-Heart-CM_5_(RYR2-)|Heart / Disease (COVID-19 only), tissue and cell type

OXTR SLC22A23 UBAC1 TBX1

6.47e-05155624d7e26696fd9c0a759524f331243db43059b33ed9
ToppCellfacs-Marrow-KLS-24m-Hematologic-megakaryocyte-erythroid_progenitor_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CRACD UBE2O SLC22A23 TMCC2

7.68e-05162624860ebf2390b4ad86475ad54717cbefcf61cd3b2a
ToppCellfacs-Marrow-KLS-24m-Hematologic-megakaryocyte-erythroid_progenitor_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CRACD UBE2O SLC22A23 TMCC2

7.68e-0516262414e9f8aaba308619eb9da90796c336e76cedac1f
ToppCellPND10-Immune-Immune_Myeloid-Monocytic-Macrophage-AM|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

NR2F6 TBC1D10B SLC9A4 TRIM55

7.68e-0516262416d625ac6702f79a83af444d2b3bf6759fd17cf6
ToppCellE12.5-Endothelial-lymphatic_endothelial_cell-endothelial_cell_of_lymphatic_vessel|E12.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

KBTBD11 FGD5 GNAS TBX1

7.86e-05163624c21114826bee1b05b411984326fef6b6e0d05316
ToppCell3'-GW_trimst-1.5-LargeIntestine-Neuronal-neuron_precursor|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SCRT1 MAGED4 CAMKV TMCC2

7.86e-0516362499cf60dc87f7ce288553091bffcd85109a02bd8f
ToppCell3'-GW_trimst-1.5-LargeIntestine-Neuronal-neuron_precursor-Neuroblast|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SCRT1 MAGED4 CAMKV TMCC2

7.86e-05163624510c0af66e82c5a8cf8edd0547dae4018a87dbbf
ToppCellE12.5-Endothelial-lymphatic_endothelial_cell|E12.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

KBTBD11 FGD5 GNAS TBX1

7.86e-051636245d49414432db259a19df50d7944581d00b69f537
ToppCellfacs-Marrow-B-cells-24m-Hematologic|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

UBE2O SLC22A23 UBAC1 TMCC2

8.05e-0516462418eeda51e69722992c3a7f699be293535a90868b
ToppCellfacs-Spleen-nan-24m-Hematologic-proerythroblast|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NR2F6 BASP1 SLC22A23 TMCC2

8.64e-0516762416bb7293fc8ca582b7cb4450917aff07b34fc70a
ToppCellfacs-Spleen-nan-24m-Hematologic|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NR2F6 BASP1 SLC22A23 TMCC2

8.64e-05167624515988c7035c550a2f072430d9d7027869593d17
ToppCellfacs-Spleen-nan-24m-Hematologic-nan|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NR2F6 BASP1 SLC22A23 TMCC2

8.64e-05167624f12d00e6c600b0bba3e4e1b1c80b791e095de931
ToppCellfacs-Marrow-B-cells-18m-Hematologic-megakaryocyte-erythroid_progenitor_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

UBE2O SLC22A23 UBAC1 TMCC2

8.84e-0516862417fb9426eeea407b26fb895b8397faca95b7552d
ToppCellfacs-Marrow-B-cells-24m-Hematologic-megakaryocyte-erythroid_progenitor_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

UBE2O SLC22A23 UBAC1 TMCC2

8.84e-0516862408fe8fa43c343c03f9a2f0b982192fde04a7c027
ToppCellfacs-Marrow-B-cells-18m-Hematologic-megakaryocyte-erythroid_progenitor_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

UBE2O SLC22A23 UBAC1 TMCC2

8.84e-05168624a61b39884851384cffd430079040546d125b2b40
ToppCellfacs-Marrow-B-cells-24m-Hematologic-megakaryocyte-erythroid_progenitor_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

UBE2O SLC22A23 UBAC1 TMCC2

8.84e-05168624d4053b2fffb19e0376b8ceb92e87ec4447d96a3e
ToppCelldroplet-Spleen-SPLEEN-1m-Myeloid-nan|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ARHGAP22 NR2F6 BASP1 MARCKS

9.04e-051696243f8aa6d2f9aa060ae1a0ea3eb47e794099fc2c2c
ToppCell3'-GW_trimst-1.5-LargeIntestine-Neuronal-neurons_A|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SHISA9 SCRT1 CAMKV CBARP

9.04e-05169624606aa4ff25380d9470ec116ca86cd20f8b19587a
ToppCelldroplet-Spleen-SPLEEN-1m-Myeloid|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ARHGAP22 NR2F6 BASP1 MARCKS

9.04e-0516962426de495c7562e0740689d0f78e803698e3e793db
ToppCell3'-GW_trimst-1.5-LargeIntestine-Neuronal-neurons_A-Branch_A1_(iMN)|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SHISA9 SCRT1 CAMKV CBARP

9.04e-05169624052aae2af5446a0de071d5dda5381b0b9a0ed54d
ToppCellFrontal_cortex-Neuronal-Inhibitory|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

CRACD SCRT1 GNAS PCDH8

9.04e-0516962478eb70dd916724e476eabccf18fb7fcec4210308
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Endothelial-lymphatic_endothelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SLC22A23 FGD5 NRG3 TBX1

9.25e-051706246035c92cd39c5ac54e7ec57d94888ee19f574639
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell_of_renal_medulla|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SLC22A23 FGD5 NRG3 TBX1

9.25e-05170624c8c42eda44b61440c96b202e7f54650046eb95d3
ToppCelldroplet-Spleen-SPLEEN-1m-Myeloid-macrophage|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ARHGAP22 NR2F6 BASP1 MARCKS

9.25e-05170624670027daec5a10dfa12246f1497b58db21d32a22
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell_of_renal_medulla-lymphatic_endothelial_cell_of_renal_medulla|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SLC22A23 FGD5 NRG3 TBX1

9.25e-05170624dcc64b73134e89ae37990d4878813b86ce91dae9
ToppCell(7)_MNP-(7)_DC_activated|(7)_MNP / Spleen cell shreds - cell class (v1) and cell subclass (v1)

ARHGAP22 CRACD SLC22A23 TMCC2

9.25e-051706244ab495b38a071fa8207331df2ce0d78a2dcd034e
ToppCelldroplet-Spleen-nan-24m-Myeloid-macrophage|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ARHGAP22 NR2F6 BASP1 MARCKS

9.46e-0517162435acc5c3e36bc605603c0d45375f2cf3c3e9d4cd
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_2-Inh_L1_VIP_PCDH20|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

CRACD ADRA1D FGD5 PCDH8

9.68e-0517262435e961c88bfe79046533396912cedf00ca81db7b
ToppCell3'_v3-lymph-node_spleen-Myeloid_Dendritic-migDC|lymph-node_spleen / Manually curated celltypes from each tissue

ARHGAP22 BASP1 SLC22A23 TRIM55

9.68e-051726241b24bed3cd8e3fa463c5e7cefdf9e99e639e2f84
ToppCellkidney_cells-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Degenerative_Medullary_Thick_Ascending_Limb_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

KIF26A NRK TNIP1 GNAS

9.90e-051736247a3115e7cf7e2f345192cde0656a7f0193594a5f
ToppCellHippocampus|World / BrainAtlas - Mouse McCarroll V32

CRACD SLC9A4 OXTR CAMKV

1.06e-04176624f120a703f6d2f2d5f55eae1aea2e6382a485828f
ToppCellfacs-Pancreas-Endocrine-24m-Epithelial-pancreatic_A_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

OXTR BASP1 GNAS PCDH8

1.06e-041766243027d34fd663c8a08544d469183dc45138916749
ToppCell3'-Broncho-tracheal-Immune_Myeloid-Dendritic-dendritic_cell|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ARHGAP22 CRACD BASP1 MARCKS

1.08e-04177624aa56129d2d5a73a10e33b7162233a4d9337ee535
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_1-Inh_L1-3_VIP_SSTR1|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

CRACD TRIM55 FGD5 PCDH8

1.08e-04177624fdab7b7ddfb06f913b8224c0c80574dc3cf4cbd4
ToppCell3'-Broncho-tracheal-Immune_Myeloid-Dendritic-dendritic_cell-Migratory_DCs-Migratory_DCs_L.1.2.1.2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ARHGAP22 CRACD BASP1 MARCKS

1.08e-04177624d78a6003ce2d15d7771ae385de252eec7e3c3eea
ToppCell3'-Broncho-tracheal-Immune_Myeloid-Dendritic-dendritic_cell-Migratory_DCs|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ARHGAP22 CRACD BASP1 MARCKS

1.08e-0417762470ca5b6fde2e38af1eb88a7d6e8746edba298191
ToppCellCOVID-19-Heart-Lymph_EC|COVID-19 / Disease (COVID-19 only), tissue and cell type

SLC22A23 KBTBD11 NRG3 TBX1

1.08e-04177624326fde0734ef0d7272693966d346ca479b9d8147
ToppCellCOVID-19-Heart-Lymph_EC|Heart / Disease (COVID-19 only), tissue and cell type

SLC22A23 KBTBD11 NRG3 TBX1

1.13e-04179624411620201a860716a8773b92f50f7b94ef34a586
ToppCellfacs-Brain_Non-Myeloid-Hippocampus-3m-Epithelial-neuronal_stem_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC22A23 ZNF516 IRS1 MARCKS

1.18e-041816244e81ec1580e9acb22c32c465eb46f83d1e9e424e
ToppCellfacs-Brain_Non-Myeloid-Hippocampus-3m-Epithelial|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC22A23 ZNF516 IRS1 MARCKS

1.18e-04181624ad30c01290fb98adbd0caed301a584761212c977
ToppCellVE-matDC|VE / Condition, Cell_class and T cell subcluster

ARHGAP22 BASP1 SLC22A23 MARCKS

1.18e-04181624982fd96ef75bc9ab2c2f4970c01b76ba7a164871
ToppCellfacs-Brain_Non-Myeloid-Hippocampus-3m-Epithelial-nan|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC22A23 ZNF516 IRS1 MARCKS

1.18e-041816243a3268a4dff8ffcb79e09f46490e138c96f8d916
ToppCellVE-matDC-|VE / Condition, Cell_class and T cell subcluster

ARHGAP22 BASP1 SLC22A23 MARCKS

1.18e-041816246252184ef098b911df50be4fe1b5565849a5b6b8
ToppCellwk_15-18-Hematologic-Meg-ery-Definitive_erythroblast|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

UBE2O SLC22A23 UBAC1 TMCC2

1.20e-0418262493841f730ca1a735eaaf5f2ccbe5c45ab0e029d1
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_2-Inh_L1-6_VIP_RGS16|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

CRACD KIF26A FGD5 PCDH8

1.20e-04182624724c33ad2fb525cbcfa5efa3362675eb42a5636d
ToppCellFetal_29-31_weeks-Immune-enucleated_erythrocyte-D062|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

UBE2O UBAC1 TMCC2 TIMM22

1.20e-04182624a99d48084aa6f5c34f4a622ae6c2165db7f0beff
ToppCell10x_3'_v3-spleen_(10x_3'_v3)-hematologic-erythrocytic-erythrocyte|spleen_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

KIF26A SLC22A23 UBAC1 TMCC2

1.23e-04183624b52d7683dc6652766e814ebe935c264ecd610c4b
ToppCellP03-Endothelial-lymphatic_endothelial_cell-endothelial_cell_of_lymphatic_vessel|P03 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

OXTR KBTBD11 GNAS TBX1

1.23e-0418362489727b4f65949ed2dce9d2e0228c79fe4280230c
ToppCell10x_3'_v3-spleen_(10x_3'_v3)-hematologic-erythrocytic|spleen_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

KIF26A SLC22A23 UBAC1 TMCC2

1.23e-041836241d77d8d8c8f78f43dd8864e76f294ee66d4942c2
ToppCellcellseq-Immune-Immune_Myeloid-Myeloid_Dendritic-maDC|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

ARHGAP22 CRACD BASP1 MARCKS

1.23e-04183624e01dacb08a9c36cf09c0b6764ce032a7232d4cdc
ToppCellFetal_29-31_weeks-Endothelial-endothelial_cell_of_lymph_vessel-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

KBTBD11 FGD5 NRG3 TBX1

1.23e-04183624bc98df870de65aff6dab295c24cbc199c7f2aa15
ToppCellP03-Endothelial-lymphatic_endothelial_cell|P03 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

OXTR KBTBD11 GNAS TBX1

1.23e-04183624113e6d8d4bb271be984af06cd6c22b180425dcfc
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Macula_Densa_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

SNAP91 NRK GNAS NRG3

1.25e-041846248fd8bd3d28d0ee6f0ef1f14e354d8eaf63a8081b
ToppCellFetal_29-31_weeks-Immune-enucleated_erythrocyte-D150|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

UBE2O SLC22A23 UBAC1 TMCC2

1.28e-04185624c4bf3ac684c1a8876b51f7af4d3a62dc47e961ee
ToppCell3'-Broncho-tracheal-Immune_Lymphocytic-Lymphocytic_B-B_cell-B_cells-B_cells_L.1.5.0.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

BASP1 BOD1L1 MARCKS SIRT1

1.28e-04185624e913c64f9b4873443d88dce270f0b7b6d1b4cbce
ToppCellFetal_29-31_weeks-Immune-enucleated_erythrocyte-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

UBE2O SLC22A23 UBAC1 TMCC2

1.28e-04185624e8f7da9641b6cf1db1093b4f301ce828fd3a529c
ToppCell3'-GW_trimst-1-SmallIntestine-Endothelial-lymphatic_endothelial-LEC4_(STAB2+)|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

IQSEC3 SLC22A23 KBTBD11 TBX1

1.28e-04185624fb84fcf7f51f53489bcb3962fa9cb483e48257ed
ToppCellPCW_05-06-Neuronal-Neuronal_postreplicative|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

SHISA9 XKR7 SCRT1 CAMKV

1.28e-04185624512f489daeb3b72d4578dc6f4d0ebb5f38d5bbab
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_2-Inh_L1-4_VIP_CHRNA2|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

CRACD KIF26A FGD5 PCDH8

1.28e-041856243189e91fe26df59bd605d2b6223ceb1779daf0b8
ToppCellPBMC-Control-cDC_10|Control / Compartment, Disease Groups and Clusters

ARHGAP22 CRACD SLC22A23 TBX1

1.28e-041856244b5a7450fed912f340da16065c1e65d626dbe8d1
ToppCellEndoth-Lymph|World / shred by cell class for parenchyma

IQSEC3 KBTBD11 MARCKS TBX1

1.28e-0418562497a6c4cd00684d4085d36ef32f7dbb99563ed357
ToppCellImmune-enucleated_erythrocyte|World / Lineage, Cell type, age group and donor

UBE2O SLC22A23 UBAC1 TMCC2

1.31e-04186624f9d5ec5cc8fd6e63bf25abe390307ec8a4a2d5a3
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_1-Inh_L1_VIP_PRSS8|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ADRA1D TRIM55 FGD5 PCDH8

1.31e-04186624fef543f188edb0d1704d9c6ace366a0f8017bf53
ToppCell3'-Child04-06-SmallIntestine-Endothelial-lymphatic_endothelial-LEC3_(ADGRG3+)|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

IQSEC3 KBTBD11 GNAS TBX1

1.31e-0418662430dd4164c101006c8d95922d89652b82dbe4b5ea
ToppCell3'-Child04-06-SmallIntestine-Endothelial-lymphatic_endothelial|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

IQSEC3 KBTBD11 GNAS TBX1

1.31e-04186624eeacf59a9e6bf1c9fd59b6b13d35e8abae228cf0
ToppCellTCGA-Pancreas-Primary_Tumor-Pancreatic_Adenocarcinoma-Ductal_Adenocarcinoma-1|TCGA-Pancreas / Sample_Type by Project: Shred V9

CRACD BOD1L1 IRS1 MAP3K1

1.31e-0418662403db813598b67b1e08f759758a1c2023396921fa
ToppCellfacs-Trachea-3m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell-smooth_muscle_cell_of_trachea_l20-23|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

IQSEC3 PRRT3 GNAS CUX1

1.34e-0418762469b47f00598d647e2a99427ebddf42c339428e47
ToppCellfacs-Brain_Non-Myeloid-Hippocampus-24m-Neuronal-neuron|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IQSEC3 ADRA1D CAMKV BASP1

1.34e-04187624e04a84989d624378141042768383b9c846901f2d
ToppCellfacs-Brain_Non-Myeloid-Hippocampus-24m-Neuronal-nan|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IQSEC3 ADRA1D CAMKV BASP1

1.34e-0418762424cc03c748e15f7ef0e6509ca5a6ca583fb9c573
ToppCellfacs-Brain_Non-Myeloid-Hippocampus-24m-Neuronal|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IQSEC3 ADRA1D CAMKV BASP1

1.34e-041876242f153b203fe79f206319603cf94d3a03ab49a05d
ToppCellChildren_(3_yrs)-Endothelial-endothelial_cell_of_lymph_vessel|Children_(3_yrs) / Lineage, Cell type, age group and donor

SLC22A23 KBTBD11 NRG3 TBX1

1.36e-04188624c2805232618a7b6f844d34e37ad458a9923dbfe1
ToppCellEndothelial-B-IPF_03|World / lung cells shred on cell class, cell subclass, sample id

KIF26A CDKN2AIP KBTBD11 TBX1

1.36e-04188624ecb74d67314a43b5805b7f2a7bb9ff6c5a60200a
ToppCellChildren_(3_yrs)-Endothelial-endothelial_cell_of_lymph_vessel-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

SLC22A23 KBTBD11 NRG3 TBX1

1.36e-041886242db80767903703e7e0a1a37c598f7877a909ee94
ToppCellPBMC_fresh-frozen-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_B-B_cell-B_c01-TCL1A|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)

BASP1 ATF7IP BOD1L1 MARCKS

1.39e-04189624b13f315f617840eb5143a4e8a33a657c20365c21
ToppCellFetal_29-31_weeks-Immune-enucleated_erythrocyte|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

UBE2O SLC22A23 UBAC1 TMCC2

1.39e-041896241900e574870fc647bfa11c732a72f3d38aab717c
ToppCellFetal_29-31_weeks-Endothelial-endothelial_cell_of_lymph_vessel|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

KBTBD11 FGD5 NRG3 TBX1

1.39e-0418962455a1776a4ce049959b3f13a43744c7314bc1f00a
ToppCell(2)_Fibroblasts-(22)_Fibro-3|World / Cell class and subclass of bone marrow stroma cells in homeostatis

ARHGAP22 TELO2 BASP1 MARCKS

1.42e-041906243aed03b87ba2c8d479048c3ceef3ff5e38746c28
ToppCell10x5'-GI_large-bowel-Lymphocytic_B-GC_B_(II)|GI_large-bowel / Manually curated celltypes from each tissue

CRACD BASP1 TRIM55 CUX1

1.42e-04190624fee64bacbb330d04dc1dc63909838f2c605d9f1f
DrugHigh Fructose Corn Syrup

FASN IRS1 SIRT1

3.82e-076623ctd:D066248
DiseaseMalignant neoplasm of breast

NR2F6 FASN KMT2D TNIP1 BOD1L1 FGD5 PCDH8 SIRT1 CUX1 MAP3K1 TP53BP1

9.43e-0610746011C0006142
DiseaseMammary Carcinoma, Human

NR2F6 FASN KMT2D TNIP1 FGD5 SIRT1 MAP3K1 TP53BP1

1.08e-05525608C4704874
DiseaseMammary Neoplasms, Human

NR2F6 FASN KMT2D TNIP1 FGD5 SIRT1 MAP3K1 TP53BP1

1.08e-05525608C1257931
DiseaseMammary Neoplasms

NR2F6 FASN KMT2D TNIP1 FGD5 SIRT1 MAP3K1 TP53BP1

1.11e-05527608C1458155
DiseaseBreast Carcinoma

NR2F6 FASN KMT2D TNIP1 FGD5 SIRT1 MAP3K1 TP53BP1

1.29e-05538608C0678222
DiseaseInsulin Sensitivity

IRS1 GNAS SIRT1

2.52e-0460603C0920563
DiseaseInsulin Resistance

IRS1 GNAS SIRT1

2.52e-0460603C0021655
Diseasenon-alcoholic fatty liver disease (biomarker_via_orthology)

FASN IRS1 SIRT1

3.19e-0465603DOID:0080208 (biomarker_via_orthology)
Diseaseintellectual disability (implicated_via_orthology)

ATF7IP BOD1L1 IRS1

4.86e-0475603DOID:1059 (implicated_via_orthology)
DiseaseSystemic Scleroderma

TNIP1 SIRT1

6.80e-0419602C0036421
DiseaseC-reactive protein measurement

ZNF469 SLC9A4 CAMKV TMCC2 TNIP1 RORA CUX1 MAP3K1 TP53BP1

6.99e-041206609EFO_0004458
DiseaseObesity

FASN IRS1 GNAS SIRT1

8.14e-04205604C0028754
Diseasediet measurement, fasting blood insulin measurement

SLC22A23 NRG3

9.15e-0422602EFO_0004466, EFO_0008111
DiseaseAdenocarcinoma of large intestine

CAMKV NRK CUX1

9.98e-0496603C1319315
DiseaseOvarian Serous Adenocarcinoma

CAMKV TRIM24

1.00e-0323602C1335177
Diseasediet measurement, HOMA-IR

SLC22A23 NRG3

1.00e-0323602EFO_0004501, EFO_0008111
Diseasereticulocyte count

ZNF469 UBE2O UBAC1 TMCC2 RORA IRS1 CUX1 MAP3K1

1.20e-031045608EFO_0007986
Diseasetype 2 diabetes mellitus (implicated_via_orthology)

NR2F6 IRS1 SIRT1

1.29e-03105603DOID:9352 (implicated_via_orthology)
Diseaselifestyle measurement, depressive symptom measurement

SNAP91 KBTBD11 RORA

1.29e-03105603EFO_0007006, EFO_0010724
Diseaseimmature platelet count

TMCC2 GNAS CUX1

1.33e-03106603EFO_0803544
DiseaseProstatic Neoplasms

KMT2D TXNDC5 IRS1 PCDH8 SIRT1 MAP3K1

1.56e-03616606C0033578
DiseaseMalignant neoplasm of prostate

KMT2D TXNDC5 IRS1 PCDH8 SIRT1 MAP3K1

1.56e-03616606C0376358
Diseaseimmature platelet fraction

TMCC2 GNAS CUX1

1.64e-03114603EFO_0009187
Diseaseblood vanadium measurement

RORA GNAS

1.71e-0330602EFO_0021533
DiseaseDiabetes Mellitus

IRS1 SIRT1

1.94e-0332602C0011849
DiseaseSchizophrenia

OXTR TXNDC5 GNAS NRG3 PCDH8 SIRT1 TBX1

2.04e-03883607C0036341
DiseaseMalignant Neoplasms

FASN GNAS CUX1

2.28e-03128603C0006826
Diseasehippocampal CA3 volume

SLC22A23 MAP3K1

2.45e-0336602EFO_0009395
Diseaseresponse to lamotrigine, maculopapular eruption, epilepsy

ADRA1D CRAMP1

3.32e-0342602EFO_0000474, EFO_0007661, EFO_1001253
Diseasehousehold income

CAMKV ATF7IP SLC22A23 MARCKS

3.42e-03304604EFO_0009695
Diseasenasopharyngeal neoplasm

IRS1 NRG3 PCDH8

3.63e-03151603EFO_0004252
Diseaseesophagus squamous cell carcinoma (is_implicated_in)

KMT2D MAP3K1

3.81e-0345602DOID:3748 (is_implicated_in)

Protein segments in the cluster

PeptideGeneStartEntry
EPEGAGSDSGDSPAS

TBC1D12

211

O60347
LEAAEAAGGASPDSP

CBARP

386

Q8N350
AAEAEAASGPSESPS

EIF3B

71

P55884
APEDAATSAAAAPGE

CUX1

1416

P39880
GDAFAASPGEAPAAS

SNAP91

441

O60641
ASPGEAPAASEGAAA

SNAP91

446

O60641
GNDPFAPSEGSAEAA

SNAP91

476

O60641
FSGDPEAADSAGNSP

ANKRD63

106

C9JTQ0
AGGYPRAAEDDSASP

NR2F6

21

P10588
RAAEDDSASPPGAAS

NR2F6

26

P10588
DSASPPGAASDAEPG

NR2F6

31

P10588
PGAASAAAASAEEGT

NRG3

11

P56975
AAVPAADPADSASGS

TENT4B

61

Q8NDF8
APAQEAATEGPSAAS

MAGED4

256

Q96JG8
AAAPAESAAPAAGEE

BASP1

126

P80723
GAPASDSKPGSSEAA

BASP1

166

P80723
LAPAGGAASASTDEA

CDKN2AIP

46

Q9NXV6
GADASSPAGAGTPEA

PCDH8

381

O95206
AGEDSVAPAAPGAGA

FGD5

116

Q6ZNL6
APDSMSESGAASPGA

KIF26A

1676

Q9ULI4
AEAANASAAPPGAEG

OXTR

11

P30559
GTSPALAGDEAASAA

IRS1

501

P35568
EAAASGAADGATAPK

IQSEC3

556

Q9UPP2
DAPPGTSASQEGDGS

BOD1L1

1766

Q8NFC6
AAAASGATSAPEGDA

CAMKV

356

Q8NCB2
AAGAPTSTAAPEAGE

DNLZ

151

Q5SXM8
GDSADAGPPAAGSAR

CRACD

876

Q6ZU35
SGESSPESAPGEGAA

CRAMP1

486

Q96RY5
SGDAPSGDVSPGDAT

ATF7IP

176

Q6VMQ6
SGAPASTDPASDDLA

ATF7IP

241

Q6VMQ6
PGSPTAAEGEAASAA

MARCKS

116

P29966
AAEDFPNGSGSPSAA

FASN

846

P49327
APDGAAAAASGSSLD

PRRT3

891

Q5FWE3
DLDSGFASGSPAPSS

PPP4R1L

296

Q9P1A2
ESVAAPDSGASSPAA

MAP3K1

126

Q13233
EASNAIDSGAAPSAP

NRK

1111

Q7Z2Y5
APSTASAAAPDGDAG

SCRT1

136

Q9BWW7
SGADPEAAPASAASA

TAF10

6

Q12962
ANSAGGPTSDAGAAA

TMCC2

41

O75069
AASDTVPAAPEGAGA

NKX1-1

56

Q15270
AEENGSLPPGDAAAS

SLC22A23

21

A1A5C7
DSGAFAADPDSGAAP

GNAS

421

Q5JWF2
AADPDSGAAPAAPAD

GNAS

426

Q5JWF2
SGAAPAAPADPDSGA

GNAS

431

Q5JWF2
AGFSDDDSSDPGSPS

SLC9A4

676

Q6AI14
PGGSPSAAGADREAA

SIRT1

11

Q96EB6
SGEASEGAEASDAPP

SHISA9

51

B4DS77
ASPQPAGDGASEAGT

TELO2

441

Q9Y4R8
PGAAGESESEGAASP

KBTBD11

16

O94819
DEAGAGASNSEPSEP

ARHGAP22

571

Q7Z5H3
FEGPRPDSSAGGSSA

ADRA1D

11

P25100
DPGGSVPSGEASAAF

TNIP1

11

Q15025
GPALPDSSGGNSADD

PRR22

311

Q8IZ63
AAADSPGSGLADEAA

ZNF516

576

Q92618
GGPSAAPSGENEAES

TRIM24

21

O15164
AAPASGSGADSEPAR

TRIM55

521

Q9BYV6
DGAAASASPDPEGAA

XKR7

6

Q5GH72
AAPDPAASEPGSSGA

RORA

6

P35398
AASEPGSSGADAAAG

RORA

11

P35398
DSASGPSSDSGPEAG

UBE2O

41

Q9C0C9
ATSASAGQAPEDPSG

TBC1D10B

201

Q4KMP7
AGPSDGLDASSPGNS

TP53BP1

1471

Q12888
DSASATALADAGSPG

ZNF469

3261

Q96JG9
PNAGGSAPETAGSAE

TIMM22

6

Q9Y584
AAAAAADGPPAADGE

TXNDC5

41

Q8NBS9
GATEEPAAAEAAGAP

SLC35G1

26

Q2M3R5
AGAATSAAAEPEGPG

TBX1

76

O43435
PPEAEGATAAASEAA

UBAC1

246

Q9BSL1
EPQEAPDSTAAGGSA

TKFC

356

Q3LXA3
PAPGAVDADSAGSDS

UHRF1BP1

886

Q6BDS2
DGDLAGATPEAPAAA

ZC3H7B

956

Q9UGR2
AADGPAASEDPSATE

KMT2D

16

O14686